s,s'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea has been researched along with Colonic Neoplasms in 3 studies
S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea: structure in first source
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Previously, we showed that the selective iNOS inhibitor S,S'-1,4-phenylenebis(1,2-ethanediyl)bis-isothiourea (PBIT) caused significant inhibition of colon carcinogenesis induced by azoxymethane (AOM), although it did not completely abrogate NO production due to the exogenous bioavailability of NO and NO generation by eNOS in tumor tissues." | 1.39 | Chemopreventive effects of PBI-Se, a selenium-containing analog of PBIT, on AOM-induced aberrant crypt foci in F344 rats. ( Amin, S; Choi, CI; Desai, D; Janakiram, NB; Mohammed, A; Rao, CV; Ravillah, D; Zhang, Y, 2013) |
| "Malignant melanoma is the most deadly form of skin cancer due to its highly metastatic nature." | 1.35 | PBISe, a novel selenium-containing drug for the treatment of malignant melanoma. ( Amin, S; Desai, D; Huh, SJ; Madhunapantula, SV; Robertson, GP; Sharma, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janakiram, NB | 1 |
| Mohammed, A | 1 |
| Ravillah, D | 1 |
| Choi, CI | 1 |
| Zhang, Y | 1 |
| Desai, D | 2 |
| Amin, S | 2 |
| Rao, CV | 2 |
| Madhunapantula, SV | 1 |
| Sharma, A | 1 |
| Huh, SJ | 1 |
| Robertson, GP | 1 |
| Kawamori, T | 1 |
| Hamid, R | 1 |
| Reddy, BS | 1 |
3 other studies available for s,s'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea and Colonic Neoplasms
| Article | Year |
|---|---|
Chemopreventive effects of PBI-Se, a selenium-containing analog of PBIT, on AOM-induced aberrant crypt foci in F344 rats.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Caco-2 Cells; Cell Line, Tumor; Cell Prolifer | 2013 |
PBISe, a novel selenium-containing drug for the treatment of malignant melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Cell Prolifer | 2008 |
Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Diseases; Colonic Neoplasms; Cu | 1999 |