s,n,n'-tripropylthiocarbamate and Morphine Abuse

s,n,n'-tripropylthiocarbamate has been researched along with Morphine Abuse in 111 studies

Research

Studies (111)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (9.91)	18.7374
1990's	5 (4.50)	18.2507
2000's	44 (39.64)	29.6817
2010's	36 (32.43)	24.3611
2020's	15 (13.51)	2.80

Authors

Authors	Studies
Chen, DS; Gao, C; Gao, Y; Hao, JR; Li, X; Liu, L; Liu, YY; Sun, N; Tong, K; Yang, L; Yang, X; You, Y; Zhu, L	1
Arezoomandan, R; Nikbakhtzadeh, M; Raeis-Abdollahi, E; Riahi, E	1
Alaei, H; Reisi, P; Rezaei, Z	1
Fatahi, Z; Haghparast, A; Karimi, S; Khodagholi, F; Zeinaddini-Meymand, A	1
Atwal, H; Ayoub, SM; Collins, SA; Di Marzo, V; Farag, M; Iannotti, FA; Leri, F; Lichtman, AH; Limebeer, CL; Mechoulam, R; Parker, LA; Piscitelli, F; Rock, EM; Smoum, R	1
Crystal, JD; Hohmann, AG; Iyer, V; Mackie, K; Slivicki, RA; Thomaz, AC	1
Feng, Z; Gao, G; Lv, Y; Ma, J; Ou, Y; Peng, J; Qi, S; Tian, Z; Wang, X; Zhou, M	1
Chang, Y; Galaj, E; Haishui, S; Jiaqi, L; Li, S; Rulan, D; Wenshuya, L; Xi, Y; Xiaorui, S; Yan, Z; Yipu, Z; Yixiao, L; Yuan, G; Zhenbang, Y	1
Farnam, A; Mahmoudi, J; Sadigh-Eteghad, S; Sarkaki, A; Yazdanfar, N	1
Ebrahimi, Z; Kahvandi, N; Karimi, SA; Komaki, A; Naderishahab, M; Sarihi, A	1
Cheng, CN; Chih Wei Huang, A; Chiu, WC; Lee, C; Wang, YC	1
Haghparast, A; Katebi, SN; Riahi, E; Torkaman-Boutorabi, A; Vousooghi, N	1
Ahmadi, S; Bradburn, S; Fotouhi, S; Khanizad, A; Masoudi, K; Mohammadi Talvar, S; Zobeiri, M	1
Haghparast, A; Jamali, S; Zarrabian, S	1
Ma, Y; Pan, Z; Sun, Y	1
Chen, JX; Huang, KM; Jiang, JX; Liu, JP; Liu, M; Xin, WJ; Yang, C; Zhang, XQ; Zhang, YX	1
Edwards, KN; Edwards, S; McGinn, MA; Pahng, AR; Paulsen, RI	1
Acher, F; Canestrelli, C; Hajasova, Z; Marie, N; Noble, F	1
Haleem, DJ; Nawaz, S; Salman, T	1
Akbarabadi, A; Makki, SM; Nazari, S; Sadat-Shirazi, MS; Safavi, P; Vousooghi, N; Zarrindast, MR; Zeraati, R	1
Farahimanesh, S; Fatahi, Z; Haghparast, A; Katebi, N; Zarrabian, S	1
Evans, CJ; Hsiao, EY; Lee, K; Nusbaum, DJ; Taylor, AMW; Vuong, HE	1
Duan, Y; Jiang, FZ; Jin, SB; Li, M; Liang, J; Shen, F; Sui, N; Zhang, JJ; Zheng, W	1
Assar, N; Haghparast, A; Mahmoudi, D; Mousavi, Z; Zarrabian, S	1
Feng, J; Ferguson, D; Heller, E; Heshmati, M; Koo, JW; Liu, X; Nestler, EJ; Neve, R; Rabkin, J; Renthal, W; Sartorelli, V; Shao, N; Shen, L	1
Franklin, KB; Harvey-Lewis, C; Perdrizet, J	2
Glück, L; Law, PY; Loktev, A; Mollereau, C; Moulédous, L; Schulz, S	1
Hou, YY; Kenny, PJ; Pan, ZZ; Tao, W; Wang, W; Zhang, Z	1
Han, J; Sui, N; Zhang, JJ	1
Franklin, KB; Harvey-Lewis, C	1
Nau, JY	1
Brisebois, AD; Franklin, KB; Harvey-Lewis, C; Yong, H	1
Laorden, ML; Lasheras, MC; Milanés, MV; Núñez, C	1
Gramage, E; Herradón, G; Vicente-Rodríguez, M	1
Chen, YH; Chen, YJ; Chow, LH; Huang, EY; Huang, TY	1
Bai, Y; Li, Y; Liu, Z; Xu, N; Zhang, Y; Zheng, X	1
Brown, RM; Cowen, MS; Lawrence, AJ; Ledent, C; Short, JL	1
Benturquia, N; Le Marec, T; Noble, F; Scherrmann, JM	1
Li, J; Li, SX; Lu, L; Peng, ZG; Wang, ZR; Zhou, M; Zhou, W	1
Kuzumaki, N; Miyatake, M; Narita, M; Suzuki, M; Suzuki, T	2
Barhight, MF; Carlezon, WA; Chartoff, EH; Mague, SD; Sawyer, AM	1
Liu, Y; Su, L; Wan, L; Wang, Y; Wang, Z; Xie, Y	1
Kurokawa, K; Ohkuma, S; Shibasaki, M	1
Esch, T; Kream, RM; Stefano, GB	1
Birnbaum, S; Han, MH; Howland, D; Nestler, EJ; Neve, R; Psifogeorgou, K; Rahman, Z; Renthal, W; Ring, RH; Young, K; Zachariou, V	1
Gieryk, A; Kubik, J; Przewlocki, R; Solecki, W; Ziolkowska, B	1
Elmer, GI; Hamilton, LR; Pieper, JO; Wise, RA	1
Jiang, Z; Liu, QF; Liu, YY; Lu, R; Wang, X; Wang, YH; Wang, ZR; Yuan, Q	1
Alcaro, A; Huber, R; Nathaniel, T; Panksepp, J; Panksepp, JB	1
Ding, ZB; Lu, L; Luo, YX; Shi, HS; Wu, P; Xue, YX; Zhu, WL	1
Contarino, A; Rouibi, K	1
Bai, J; Liu, H; Luo, FC; Lv, T; Nakamura, H; Qi, L; Wang, SD; Yodoi, J	1
Li, M; Li, S; Quan, L; Song, T; Sun, ZS; Tian, W; Zhang, M; Zhao, M	1
Doyle, E; Elmer, GI; Lee, AD; Lee, NH; Luu, TV; Mayo, CL; Tapocik, JD; Wang, BD	1
Graves, SM; Napier, TC; Persons, AL; Riddle, JL	1
Liu, XD; Liu, Z; Yu, LC; Zhang, JJ	1
Balter, RE; Dykstra, LA	1
Chen, J; Chi, ZQ; He, L; Kang, S; Li, M; Liu, JG; Liu, WT; Liu, Y; Wang, WS; Yu, C	1
Hoseini, SE; Mokhtari, M; Razmi, N; Tavakoli, F; Vahdati, A; Vessal, M	1
Cai, S; Huang, M; Liu, C; Peng, Y; Zhang, M	1
Kozela, E; Popik, P; Slusher, BS; Wozniak, KM; Wróbel, M	1
Che, LW; Chen, J; Chi, ZQ; Gao, C; Xu, XJ	1
Castañé, A; Célérier, E; Ghozland, S; Maldonado, R; Nyberg, F; Yazdi, MT	1
Kato, H; Narita, M; Oe, K; Shibasaki, M; Suzuki, T; Yajima, Y; Yamazaki, M	1
Aguilar, MA; Manzanedo, C; Miñarro, J; Navarro, M; Rodríguez-Arias, M	1
Fleck, MW; Glick, SD; He, LW; Jokiel, PA; Kuehne, ME; Maisonneuve, IM; Pace, CJ	1
Alcaro, A; Puglisi-Allegra, S; Ventura, R	1
Chen, JH; Cui, CL; Han, JS; Liang, J; Wang, GB	1
Nagumo, Y; Narita, M; Shibasaki, M; Suzuki, T; Yajima, Y	1
Aguilar, MA; Miñarro, J; Ribeiro Do Couto, B; Rodríguez-Arias, M	1
Burns, LH; Olmstead, MC	1
Alberini, CM; Brown, SD; Castellini, C; Milekic, MH	1
Cao, J; Dong, Z; Han, H; Hao, W; Wang, M; Xu, L	1
Chu, NN; Cui, CL; Guo, CY; Han, JS; Ma, YY	1
Golhasani-Keshtan, F; Haeri-Rohani, A; Rezayof, A; Zarrindast, MR	1
Nabeshima, T; Nakajima, A; Nitta, A; Niwa, M; Noda, Y; Saito, K; Seishima, M; Yamada, Y	1
Cuadra, GR; de Olmos, JS; de Olmos, S; Orsingher, OA; Valdomero, A; Velazquez, EE	1
Brunzell, DH; Hawes, JJ; Langel, U; Narasimhaiah, R; Picciotto, MR; Wynick, D	1
Dong, Y; Hao, Y; Qi, J; Sun, J; Wu, CF; Yang, J	1
Kobayashi, Y; Kurahashi, K; Nanjo, K; Narita, M; Niikura, K; Okutsu, D; Suzuki, T; Tsurukawa, Y	1
Adriani, W; Capone, F; Dambinova, S; Granstrem, O; Izykenova, G; Laviola, G; Shumilina, M	1
Basseda, Z; Dehpour, AR; Esmaeili, B	1
Bozarth, MA; Wise, RA	4
Befort, K; Dierich, A; Dollé, P; Hanoune, J; Kieffer, BL; Kitchen, I; Le Meur, M; Maldonado, R; Matthes, HW; Roques, BP; Simonin, F; Slowe, S; Tzavara, E; Valverde, O	1
Bespalov, AIu; Zvartau, EE	1
Agmo, A; Huston, JP; Schildein, S; Schwarting, RK	1
Collins, ED; Comer, SD; Fischman, MW	1
Kovács, GL; Sarnyai, Z; Szabó, G	1
Gomez, F; Grigson, PS; Leo, NA	1
Betancur, C; Caron, MG; Fauchey, V; Giros, B; Gonon, F; Hamon, M; Jaber, M; Maldonado, R; Roques, BP; Roubert, C; Spielewoy, C	1
Glick, SD; Maisonneuve, IM; Szumlinski, KK	1
De Felipe, C; Hunt, SP; Murtra, P; Sheasby, AM	1
Angeletti, S; Ciccocioppo, R; Massi, M; Sanna, PP; Weiss, F	1
Aoki, T; Narita, M; Suzuki, T	1
Aoki, T; Narita, M; Ozaki, S; Suzuki, T; Yajima, Y	1
Elmer, G; Funada, M; Hall, FS; Li, XF; Pieper, J; Sora, I; Uhl, GR	1
Laviolette, SR; Nader, K; van der Kooy, D	1
Cupo, A; Nieto, MM; Noble, F; Roques, BP; Wilson, J	1
Aguilar, MA; Felip, CM; Miñarro, J; Rodríguez-Arias, M	1
Cox, RS; Crane, AM; Glick, SD	1
Iversen, SD; Tye, NC	1
Collier, HO	1
Ladewig, D	1
Glick, SD	1
Goldstein, A	1
Goldberg, SR; Schuster, CR	1

Reviews

6 review(s) available for s,n,n'-tripropylthiocarbamate and Morphine Abuse

Article	Year
Implication of activated astrocytes in the development of drug dependence: differences between methamphetamine and morphine. Annals of the New York Academy of Sciences, 2008, Volume: 1141 Topics: Amphetamine-Related Disorders; Animals; Astrocytes; Cells, Cultured; Culture Media, Conditioned; Cytokines; Gyrus Cinguli; Humans; Janus Kinases; Methamphetamine; Mice; Morphine; Morphine Dependence; Motor Activity; Multipotent Stem Cells; Nerve Tissue Proteins; Neuronal Plasticity; Nucleus Accumbens; Protein Kinase C; Rats; Reward; Signal Transduction; STAT Transcription Factors	2008
Revisiting tolerance from the endogenous morphine perspective. Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:9 Topics: Animals; Brain; Drug Tolerance; Humans; Immune System; Love; Morphine; Morphine Dependence; Narcotics; Protein Isoforms; Receptors, Opioid; Reward; Signal Transduction	2009
Drug-sensitive reward in crayfish: an invertebrate model system for the study of SEEKING, reward, addiction, and withdrawal. Neuroscience and biobehavioral reviews, 2011, Volume: 35, Issue:9 Topics: Amphetamine-Related Disorders; Animals; Astacoidea; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Morphine Dependence; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders	2011
[Role of astrocytes in rewarding effects of drugs of abuse]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2006, Volume: 26, Issue:1 Topics: Animals; Astrocytes; Cyclin-Dependent Kinases; Humans; Morphine Dependence; Neuronal Plasticity; Protein-Tyrosine Kinases; Reward; Substance-Related Disorders	2006
Oxytocin and addiction: a review. Psychoneuroendocrinology, 1998, Volume: 23, Issue:8 Topics: Alcoholism; Animals; Brain; Cocaine-Related Disorders; Humans; Mice; Morphine Dependence; Oxytocin; Rats; Reward; Substance-Related Disorders	1998
Drug dependence: a pharmacological analysis. The British journal of addiction to alcohol and other drugs, 1972, Volume: 67, Issue:4 Topics: Acetylcholine; Animals; Atropine; Brain Chemistry; Catecholamines; Cerebral Cortex; Chemoreceptor Cells; Cycloheximide; Drug Tolerance; Euphoria; Fenclonine; Humans; Indomethacin; Mice; Morphine; Morphine Dependence; Rats; Reward; Self Stimulation; Substance Withdrawal Syndrome; Substance-Related Disorders	1972

Trials

1 trial(s) available for s,n,n'-tripropylthiocarbamate and Morphine Abuse

Article	Year
Choice between money and intranasal heroin in morphine-maintained humans. Behavioural pharmacology, 1997, Volume: 8, Issue:8 Topics: Administration, Intranasal; Adult; Dose-Response Relationship, Drug; Heroin; Humans; Male; Morphine; Morphine Dependence; Narcotics; Psychomotor Performance; Reward; Self Administration; Time Factors	1997

Other Studies

104 other study(ies) available for s,n,n'-tripropylthiocarbamate and Morphine Abuse

Article	Year
dCA1-NAc shell glutamatergic projection mediates context-induced memory recall of morphine. Pharmacological research, 2021, Volume: 172 Topics: Analgesics, Opioid; Animals; CA1 Region, Hippocampal; Conditioning, Operant; Glutamic Acid; Male; Memory; Mice, Inbred C57BL; Morphine; Morphine Dependence; Neurons; Nucleus Accumbens; Reward; Synaptic Transmission	2021
The interaction between sexual reward/ deprivation and the acquisition, extinction and reinstatement of morphine-seeking behavior. Behavioural brain research, 2022, 01-07, Volume: 416 Topics: Animals; Behavior, Animal; Conditioning, Classical; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Mice; Morphine; Morphine Dependence; Reward; Sexual Behavior; Substance-Related Disorders	2022
Effects of electrical stimulation and temporary inactivation of basolateral amygdala on morphine-induced conditioned place preference in rats. Neuroscience letters, 2022, 03-23, Volume: 774 Topics: Amygdala; Animals; Basolateral Nuclear Complex; Electric Stimulation; Lidocaine; Morphine; Morphine Dependence; Rats; Rats, Wistar; Reward	2022
Impairment of cost-benefit decision making in morphine-dependent rats is partly mediated via the alteration of BDNF and p-CREB levels in the nucleus accumbens. Pharmacology, biochemistry, and behavior, 2020, Volume: 194 Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Decision Making; Male; Maze Learning; Morphine; Morphine Dependence; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome	2020
Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats. Psychopharmacology, 2020, Volume: 237, Issue:9 Topics: Alanine; Analgesics, Opioid; Animals; Glycine; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Oleic Acids; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome	2020
The cannabinoid CB European journal of pharmacology, 2020, Nov-05, Volume: 886 Topics: Analgesics; Analgesics, Opioid; Animals; Cannabinoid Receptor Agonists; Conditioning, Operant; Dose-Response Relationship, Drug; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Neuralgia; Nociception; Paclitaxel; Purines; Pyrans; Receptor, Cannabinoid, CB2; Reward; Substance Withdrawal Syndrome	2020
NPY alterations induced by chronic morphine exposure affect the maintenance and reinstatement of morphine conditioned place preference. Neuropharmacology, 2020, 12-15, Volume: 181 Topics: Animals; Conditioning, Classical; Conditioning, Operant; Conditioning, Psychological; Extinction, Psychological; Male; Morphine; Morphine Dependence; Narcotics; Neuronal Plasticity; Neuropeptide Y; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Reward	2020
Exogenous SO European journal of pharmacology, 2021, Apr-05, Volume: 896 Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Humans; Memory Consolidation; Mice, Inbred C57BL; Morphine; Morphine Dependence; Reward; Sulfites; Sulfur Dioxide; Time Factors	2021
Enriched environment and social isolation differentially modulate addiction-related behaviors in male offspring of morphine-addicted dams: The possible role of μ-opioid receptors and ΔFosB in the brain reward pathway. Brain research bulletin, 2021, Volume: 170 Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain; Female; Housing, Animal; Morphine; Morphine Dependence; Proto-Oncogene Proteins c-fos; Rats, Wistar; Receptors, Opioid, mu; Reward; Social Environment; Social Isolation	2021
The role of mGlu4 receptors within the nucleus accumbens in acquisition and expression of morphine-induced conditioned place preference in male rats. BMC neuroscience, 2021, 03-21, Volume: 22, Issue:1 Topics: Anilides; Animals; Conditioning, Classical; Cyclohexanecarboxylic Acids; Male; Morphine Dependence; Neural Pathways; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reward	2021
Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neuroscience letters, 2021, 08-24, Volume: 760 Topics: Amygdala; Animals; Conditioning, Operant; Disease Models, Animal; Hippocampus; Humans; Interleukin-1beta; Male; Morphine; Morphine Dependence; Neuroinflammatory Diseases; Prefrontal Cortex; Rats; Reward; Saccharin; Signal Transduction	2021
Systemic administration of N-acetylcysteine during the extinction period and on the reinstatement day decreased the maintenance of morphine rewarding properties in the rats. Behavioural brain research, 2021, 09-10, Volume: 413 Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Conditioning, Classical; Disease Models, Animal; Locomotion; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Wistar; Reinforcement, Psychology; Reward	2021
Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research, 2021, 09-24, Volume: 414 Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Drug Tolerance; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Wistar; Reward; RNA, Long Noncoding	2021
Similar role of mPFC orexin-1 receptors in the acquisition and expression of morphine- and food-induced conditioned place preference in male rats. Neuropharmacology, 2021, 10-15, Volume: 198 Topics: Animals; Benzoxazoles; Conditioning, Operant; Drug-Seeking Behavior; Food; Male; Morphine; Morphine Dependence; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Prefrontal Cortex; Rats; Rats, Wistar; Reward; Urea	2021
Increased entrances to side compartments indicate incubation of craving in morphine-induced rat and tree shrew CPP models. Pharmacology, biochemistry, and behavior, 2017, Volume: 159 Topics: Animals; Conditioning, Operant; Craving; Cues; Environment; Male; Morphine Dependence; Psychology, Experimental; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Substance Withdrawal Syndrome; Tupaiidae	2017
Activation of TLR4/STAT3 signaling in VTA contributes to the acquisition and maintenance of morphine-induced conditioned place preference. Behavioural brain research, 2017, 09-29, Volume: 335 Topics: Animals; Conditioning, Classical; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Signal Transduction; STAT3 Transcription Factor; Toll-Like Receptor 4; Ventral Tegmental Area	2017
Neurobiological Correlates of Pain Avoidance-Like Behavior in Morphine-Dependent and Non-Dependent Rats. Neuroscience, 2017, Dec-16, Volume: 366 Topics: Analgesics, Opioid; Animals; Avoidance Learning; Brain; Male; Morphine; Morphine Dependence; Motivation; Pain; Rats, Wistar; Reward; Substance Withdrawal Syndrome	2017
Role of mGlu7 receptor in morphine rewarding effects is uncovered by a novel orthosteric agonist. Neuropharmacology, 2018, 03-15, Volume: 131 Topics: Anhedonia; Animals; Anxiety; Chromones; Conditioning, Psychological; Depression; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Morphine; Morphine Dependence; Movement; Narcotics; Receptors, Metabotropic Glutamate; Reward; Spatial Behavior; Spatial Memory	2018
Dopamine and serotonin metabolism associated with morphine reward and its inhibition with buspirone: A study in the rat striatum. Pharmacology, biochemistry, and behavior, 2018, Volume: 170 Topics: Animals; Buspirone; Caudate Nucleus; Corpus Striatum; Dopamine; Male; Morphine; Morphine Dependence; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Reward; Serotonin	2018
Adult rat morphine exposure changes morphine preference, anxiety, and the brain expression of dopamine receptors in male offspring. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2018, Volume: 69 Topics: Aging; Animals; Anxiety; Brain Chemistry; Female; Male; Morphine; Morphine Dependence; Narcotics; Pregnancy; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Dopamine; Reward; Sex Characteristics; Survival Analysis	2018
Involvement of D1- and D2-like dopamine receptors in the dentate gyrus in the acquisition, expression, and extinction of the morphine-induced conditioned place preference in rats. Behavioural brain research, 2018, 11-01, Volume: 353 Topics: Animals; Benzazepines; Conditioning, Psychological; Dentate Gyrus; Dopamine Antagonists; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Morphine; Morphine Dependence; Motor Activity; Narcotics; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Spatial Behavior; Sulpiride	2018
The gut microbiota mediates reward and sensory responses associated with regimen-selective morphine dependence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:13 Topics: Analgesics, Opioid; Animals; Gastrointestinal Microbiome; Intestinal Absorption; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Reward	2018
DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self-administration in rats. Addiction biology, 2020, Volume: 25, Issue:2 Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Self Administration	2020
Role of orexin-1 and -2 receptors within the nucleus accumbens in the acquisition of sensitization to morphine in rats. Behavioural brain research, 2019, 11-05, Volume: 373 Topics: Animals; Benzoxazoles; Conditioning, Classical; Conditioning, Operant; Conditioning, Psychological; Drug Interactions; Drug Tolerance; Isoquinolines; Male; Morphine; Morphine Dependence; Naphthyridines; Nucleus Accumbens; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Pyridines; Rats; Rats, Wistar; Reward; Urea	2019
Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Oct-09, Volume: 33, Issue:41 Topics: Animals; Chromatin Immunoprecipitation; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Immunoblotting; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Reward; Signal Transduction; Sirtuin 1; Sirtuin 2	2013
Delay discounting of oral morphine and sweetened juice rewards in dependent and non-dependent rats. Psychopharmacology, 2014, Volume: 231, Issue:13 Topics: Analgesics, Opioid; Animals; Beverages; Choice Behavior; Delay Discounting; Impulsive Behavior; Male; Morphine; Morphine Dependence; Rats; Rats, Long-Evans; Reward; Sweetening Agents	2014
Loss of morphine reward and dependence in mice lacking G protein-coupled receptor kinase 5. Biological psychiatry, 2014, Nov-15, Volume: 76, Issue:10 Topics: Analgesics, Opioid; Animals; Benzimidazoles; Conditioning, Psychological; Drug Tolerance; Fentanyl; G-Protein-Coupled Receptor Kinase 3; G-Protein-Coupled Receptor Kinase 5; Gene Knockout Techniques; Mice; Mice, Knockout; Morphine; Morphine Dependence; Nociception; Phosphorylation; Protein Isoforms; Receptors, Opioid, mu; Reward	2014
MeCP2 repression of G9a in regulation of pain and morphine reward. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Jul-02, Volume: 34, Issue:27 Topics: Amygdala; Animals; Brain-Derived Neurotrophic Factor; Chronic Pain; Conditioning, Classical; Crosses, Genetic; Disease Susceptibility; Down-Regulation; Emotions; Epigenesis, Genetic; Exploratory Behavior; Female; Gene Expression Regulation; Gene Knockdown Techniques; Genetic Vectors; Histone-Lysine N-Methyltransferase; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Narcotics; Nerve Tissue Proteins; Recombinant Fusion Proteins; Reinforcement, Psychology; Reward; Transgenes	2014
Okadaic acid blocks the effects of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats. Neuropharmacology, 2014, Volume: 86 Topics: Animals; Azacitidine; CA1 Region, Hippocampal; Cerebral Cortex; Conditioning, Psychological; Decitabine; Disease Models, Animal; DNA Modification Methylases; Enzyme Inhibitors; Male; Memory; Morphine; Morphine Dependence; Narcotics; Okadaic Acid; Rats, Sprague-Dawley; Reward; Spatial Behavior	2014
The effect of acute morphine on delay discounting in dependent and non-dependent rats. Psychopharmacology, 2015, Volume: 232, Issue:5 Topics: Analgesics, Opioid; Animals; Delay Discounting; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Morphine; Morphine Dependence; Rats; Reward; Sucrose	2015
[To destroy or not to destroy the "reward's neural circuitry" in morphine abusers?]. Revue medicale suisse, 2014, Sep-17, Volume: 10, Issue:442 Topics: Cell Death; Cognition; Consciousness; Deep Brain Stimulation; Humans; Morphine Dependence; Nerve Net; Reward	2014
Naloxone-precipitated withdrawal causes an increase in impulsivity in morphine-dependent rats. Behavioural pharmacology, 2015, Volume: 26, Issue:3 Topics: Animals; Delay Discounting; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Long-Evans; Reward; Substance Withdrawal Syndrome	2015
Corticotropin-releasing factor 1 receptor mediates the activity of the reward system evoked by morphine-induced conditioned place preference. Neuropharmacology, 2015, Volume: 95 Topics: Animals; Conditioning, Operant; Hormone Antagonists; Locus Coeruleus; Male; Mice; Morphine; Morphine Dependence; Narcotics; Neurons; Nucleus Accumbens; Pyrimidines; Pyrroles; Random Allocation; Receptors, Corticotropin-Releasing Hormone; Reward; Spatial Behavior; Ventral Tegmental Area	2015
Pleiotrophin modulates morphine withdrawal but has no effects on morphine-conditioned place preference. Neuroscience letters, 2015, Sep-14, Volume: 604 Topics: Animals; Carrier Proteins; Conditioning, Classical; Cytokines; Mice, Knockout; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Reward; Substance Withdrawal Syndrome	2015
Chronic administration of nandrolone increases susceptibility to morphine dependence without correlation with LVV-hemorphin 7 in rats. Neuropeptides, 2016, Volume: 59 Topics: Animals; Association Learning; Brain; Conditioning, Psychological; Dopamine; Hemoglobins; Male; Morphine; Morphine Dependence; Motor Activity; Nandrolone; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reward	2016
The consummatory and motivational behaviors for natural rewards following long-term withdrawal from morphine: no anhedonia but persistent maladaptive behaviors for high-value rewards. Psychopharmacology, 2017, Volume: 234, Issue:8 Topics: Anhedonia; Animals; Behavior, Animal; Feeding Behavior; Female; Male; Morphine; Morphine Dependence; Motivation; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome; Sucrose	2017
A differential role for the adenosine A2A receptor in opiate reinforcement vs opiate-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:4 Topics: Analysis of Variance; Animals; Behavior, Addictive; Conditioning, Operant; Cues; Male; Mice; Mice, Knockout; Morphine; Morphine Dependence; Motor Activity; Receptor, Adenosine A2A; Reward; Self Administration; Spatial Behavior; Sucrose	2009
Effects of nitrous oxide on dopamine release in the rat nucleus accumbens and expectation of reward. Neuroscience, 2008, Aug-13, Volume: 155, Issue:2 Topics: Analgesics, Opioid; Animals; Conditioning, Psychological; Dopamine; Drug Interactions; Male; Mice; Mice, Inbred Strains; Microdialysis; Morphine; Morphine Dependence; Nitrous Oxide; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Spatial Behavior	2008
Inhibition of Period1 gene attenuates the morphine-induced ERK-CREB activation in frontal cortex, hippocampus, and striatum in mice. The American journal of drug and alcohol abuse, 2008, Volume: 34, Issue:6 Topics: Animals; Cell Cycle Proteins; Conditioning, Operant; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; DNA, Catalytic; Drug Delivery Systems; Extracellular Signal-Regulated MAP Kinases; Frontal Lobe; Gene Expression Regulation; Hippocampus; Male; Mice; Mice, Inbred BALB C; Morphine; Morphine Dependence; Nuclear Proteins; Period Circadian Proteins; Phosphorylation; Reward; RNA, Messenger	2008
Anatomically dissociable effects of dopamine D1 receptor agonists on reward and relief of withdrawal in morphine-dependent rats. Psychopharmacology, 2009, Volume: 204, Issue:2 Topics: Animals; Benzazepines; Brain; Conditioning, Operant; Dopamine Agonists; Male; Microinjections; Morphine Dependence; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Substance Withdrawal Syndrome; Ventral Tegmental Area	2009
Protein receptor for activated C kinase 1 is involved in morphine reward in mice. Neuroscience, 2009, Jul-07, Volume: 161, Issue:3 Topics: Analysis of Variance; Animals; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Narcotics; Neuropeptides; Prefrontal Cortex; Random Allocation; Receptors for Activated C Kinase; Reverse Transcriptase Polymerase Chain Reaction; Reward; RNA, Messenger; RNA, Small Interfering; Spatial Behavior	2009
Role of alpha2/delta subunit in the development of morphine-induced rewarding effect and behavioral sensitization. Neuroscience, 2009, Oct-20, Volume: 163, Issue:3 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Calcium Channels, L-Type; Conditioning, Psychological; Frontal Lobe; Limbic System; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Protein Subunits; Reward; Up-Regulation	2009
Brain region specific actions of regulator of G protein signaling 4 oppose morphine reward and dependence but promote analgesia. Biological psychiatry, 2010, Apr-15, Volume: 67, Issue:8 Topics: Adenoviridae; Analgesics, Opioid; Animals; Behavior, Animal; Blotting, Western; Conditioning, Operant; Electrophysiology; Gene Transfer Techniques; Immunoprecipitation; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Mutation; Pain Measurement; Reaction Time; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Reward; RGS Proteins; Signal Transduction	2010
Forebrain PENK and PDYN gene expression levels in three inbred strains of mice and their relationship to genotype-dependent morphine reward sensitivity. Psychopharmacology, 2010, Volume: 208, Issue:2 Topics: Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Psychological; Cues; Enkephalins; Gene Expression Regulation; Genotype; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine Dependence; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phenotype; Protein Precursors; Receptors, Opioid, kappa; Reward; RNA, Messenger; Species Specificity	2010
Qualitative differences between C57BL/6J and DBA/2J mice in morphine potentiation of brain stimulation reward and intravenous self-administration. Psychopharmacology, 2010, Volume: 208, Issue:2 Topics: Amphetamine; Amphetamine-Related Disorders; Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Genotype; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Morphine Dependence; Phenotype; Reinforcement, Psychology; Reward; Self Administration; Species Specificity	2010
RACK1, a potential target to decrease morphine reward in mice. Archives italiennes de biologie, 2009, Volume: 147, Issue:4 Topics: Animals; Brain; Conditioning, Operant; Disease Models, Animal; Drug Administration Schedule; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinases; Morphine; Morphine Dependence; Narcotics; Neuropeptides; Receptors for Activated C Kinase; Reward	2009
Effects of sleep deprivation on retrieval and reconsolidation of morphine reward memory in rats. Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:2 Topics: Animals; Behavior, Addictive; Conditioning, Psychological; Male; Memory; Morphine Dependence; Rats; Rats, Sprague-Dawley; Reward; Sleep Deprivation	2011
Increased motivation to eat in opiate-withdrawn mice. Psychopharmacology, 2012, Volume: 221, Issue:4 Topics: Analgesics, Opioid; Animals; Cognition; Conditioning, Operant; Eating; Female; Mice; Morphine; Morphine Dependence; Motivation; Reward; Substance Withdrawal Syndrome; Time Factors	2012
Geranylgeranylacetone protects mice against morphine-induced hyperlocomotion, rewarding effect, and withdrawal syndrome. Free radical biology & medicine, 2012, Apr-01, Volume: 52, Issue:7 Topics: Analgesics, Opioid; Animals; Blotting, Western; Brain; Cell Movement; Diterpenes; HSP70 Heat-Shock Proteins; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Reward; Substance Withdrawal Syndrome; Thioredoxins	2012
Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex. PloS one, 2012, Volume: 7, Issue:3 Topics: Animals; Base Sequence; Cocaine-Related Disorders; Conditioning, Psychological; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Food; Male; Methionine; Mice; Mice, Inbred C57BL; Morphine Dependence; Nucleus Accumbens; Prefrontal Cortex; Reward; RNA, Messenger	2012
The effect of morphine dependence on impulsive choice in rats. Psychopharmacology, 2012, Volume: 223, Issue:4 Topics: Animals; Choice Behavior; Impulsive Behavior; Male; Morphine Dependence; Motivation; Random Allocation; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Substance Withdrawal Syndrome; Sucrose; Time Factors	2012
Neuroplasticity, axonal guidance and micro-RNA genes are associated with morphine self-administration behavior. Addiction biology, 2013, Volume: 18, Issue:3 Topics: Adaptation, Physiological; Analysis of Variance; Animals; Axons; Infusions, Intravenous; Mice; Mice, Inbred C57BL; Microarray Analysis; MicroRNAs; Morphine; Morphine Dependence; Narcotics; Neuronal Plasticity; Reinforcement, Psychology; Reward; Self Administration	2013
The atypical antidepressant mirtazapine attenuates expression of morphine-induced place preference and motor sensitization. Brain research, 2012, Sep-07, Volume: 1472 Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Conditioning, Operant; Cues; Disease Models, Animal; Male; Mianserin; Mirtazapine; Morphine; Morphine Dependence; Motor Activity; Rats; Rats, Sprague-Dawley; Reward	2012
Increases in αCaMKII phosphorylated on Thr286 in the nucleus accumbens shell but not the core during priming-induced reinstatement of morphine-seeking in rats. Neuroscience letters, 2012, Sep-20, Volume: 526, Issue:1 Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Male; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration	2012
The effect of environmental factors on morphine withdrawal in C57BL/6J mice: running wheel access and group housing. Psychopharmacology, 2012, Volume: 224, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Hot Temperature; Housing, Animal; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Reward; Running; Substance Withdrawal Syndrome; Temperature; Time Factors	2012
Extinction of aversive memories associated with morphine withdrawal requires ERK-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Oct-03, Volume: 32, Issue:40 Topics: Acetylation; Animals; Association Learning; Avoidance Learning; Brain-Derived Neurotrophic Factor; Butadienes; Chromatin Assembly and Disassembly; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Epigenetic Repression; Extinction, Psychological; Histone Deacetylase Inhibitors; Histones; Male; MAP Kinase Signaling System; Morphine; Morphine Dependence; Nitriles; Prefrontal Cortex; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome; Transcription, Genetic	2012
Role of music in morphine rewarding effects in mice using conditioned place preference method. Neuro endocrinology letters, 2012, Volume: 33, Issue:7 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Choice Behavior; Conditioning, Psychological; Male; Mice; Morphine; Morphine Dependence; Music; Nucleus Accumbens; Random Allocation; Reward; Ventral Tegmental Area	2012
[Effects of sulpiride on morphine-induced reward and its relation to cyclic AMP levels in mice]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 2000, Volume: 31, Issue:3 Topics: Animals; Conditioning, Classical; Cyclic AMP; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Male; Mice; Morphine Dependence; Random Allocation; Reward; Sulpiride	2000
Morphine tolerance and reward but not expression of morphine dependence are inhibited by the selective glutamate carboxypeptidase II (GCP II, NAALADase) inhibitor, 2-PMPA. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Carboxypeptidases; Drug Tolerance; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Male; Mice; Mice, Inbred C57BL; Morphine Dependence; Organophosphorus Compounds; Pain Measurement; Reward	2003
Ohmefentanyl stereoisomers induce changes of CREB phosphorylation in hippocampus of mice in conditioned place preference paradigm. Cell research, 2003, Volume: 13, Issue:1 Topics: Analgesics; Animals; Behavior, Animal; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Fentanyl; Hippocampus; Ketamine; Male; Mice; Morphine; Morphine Dependence; Phosphorylation; Reward; Stereoisomerism; Substance Withdrawal Syndrome; Substance-Related Disorders	2003
Effects of nandrolone on acute morphine responses, tolerance and dependence in mice. European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2 Topics: Anabolic Agents; Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Nandrolone; Nociceptors; Pain; Pain Measurement; Reward; Substance Withdrawal Syndrome; Time Factors	2003
Implication of spinal protein kinase C in the suppression of morphine-induced rewarding effect under a neuropathic pain-like state in mice. Neuroscience, 2004, Volume: 125, Issue:3 Topics: Analgesics, Opioid; Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Indoles; Ligation; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Neuralgia; Protein Kinase C; Pyrroles; Reward; Sciatic Neuropathy; Spinal Cord; Up-Regulation	2004
Cannabinoid agonist-induced sensitisation to morphine place preference in mice. Neuroreport, 2004, Jun-07, Volume: 15, Issue:8 Topics: Animals; Behavior, Animal; Benzoxazines; Brain; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Morphine; Morphine Dependence; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Reward; Rimonabant; Spatial Behavior	2004
Novel iboga alkaloid congeners block nicotinic receptors and reduce drug self-administration. European journal of pharmacology, 2004, May-25, Volume: 492, Issue:2-3 Topics: Amphetamine-Related Disorders; Animals; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Ibogaine; Morphine Dependence; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reward; Self Administration; Tabernaemontana	2004
Prefrontal cortical norepinephrine release is critical for morphine-induced reward, reinstatement and dopamine release in the nucleus accumbens. Cerebral cortex (New York, N.Y. : 1991), 2005, Volume: 15, Issue:12 Topics: Analgesics, Opioid; Animals; Avoidance Learning; Conditioning, Psychological; Dopamine; Extinction, Psychological; Male; Mice; Mice, Inbred C57BL; Microdialysis; Morphine; Morphine Dependence; Norepinephrine; Nucleus Accumbens; Prefrontal Cortex; Reward	2005
Repeated 2 Hz peripheral electrical stimulations suppress morphine-induced CPP and improve spatial memory ability in rats. Experimental neurology, 2005, Volume: 194, Issue:2 Topics: Animals; Brain; Conditioning, Psychological; Disease Models, Animal; Electroacupuncture; Male; Maze Learning; Memory Disorders; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Sprague-Dawley; Recovery of Function; Reward; Substance Withdrawal Syndrome; Treatment Outcome	2005
Implication of cyclin-dependent kinase 5 in the development of psychological dependence on and behavioral sensitization to morphine. Journal of neurochemistry, 2005, Volume: 93, Issue:6 Topics: Animals; Behavior, Animal; Brain Chemistry; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Gyrus Cinguli; Male; Mice; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Neuronal Plasticity; Phosphorylation; Purines; Reward; Roscovitine; Up-Regulation	2005
Long-lasting rewarding effects of morphine induced by drug primings. Brain research, 2005, Jul-19, Volume: 1050, Issue:1-2 Topics: Analgesics, Opioid; Animals; Brain Chemistry; Chronic Disease; Conditioning, Psychological; Extinction, Psychological; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Recurrence; Reward; Time Factors	2005
Ultra-low-dose naltrexone suppresses rewarding effects of opiates and aversive effects of opiate withdrawal in rats. Psychopharmacology, 2005, Volume: 181, Issue:3 Topics: Animals; Avoidance Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Female; Injections, Subcutaneous; Morphine Dependence; Motivation; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Orientation; Oxycodone; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome	2005
Persistent disruption of an established morphine conditioned place preference. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-15, Volume: 26, Issue:11 Topics: Amnesia, Retrograde; Amygdala; Animals; Anisomycin; Association Learning; Conditioning, Classical; Cues; Cycloheximide; Hippocampus; Learning; Male; Mental Recall; Microinjections; Morphine; Morphine Dependence; Nerve Tissue Proteins; Nucleus Accumbens; Organ Specificity; Protein Synthesis Inhibitors; Rats; Rats, Long-Evans; Reward; Spatial Behavior; Time Factors; Ventral Tegmental Area	2006
Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens. Hippocampus, 2006, Volume: 16, Issue:10 Topics: Animals; Conditioning, Psychological; Cues; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Hippocampus; Hormone Antagonists; Male; Memory; Mifepristone; Morphine; Morphine Dependence; Motivation; Narcotics; Nerve Net; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward; Solvents	2006
NR2B-containing NMDA receptor is required for morphine-but not stress-induced reinstatement. Experimental neurology, 2007, Volume: 203, Issue:2 Topics: Amygdala; Animals; Conditioning, Operant; Excitatory Amino Acid Antagonists; Extinction, Psychological; Food Deprivation; Hippocampus; Immunoblotting; Male; Microinjections; Morphine; Morphine Dependence; Narcotics; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Reward; Stress, Psychological; Swimming	2007
Morphine-induced place preference: involvement of the central amygdala NMDA receptors. Brain research, 2007, Feb-16, Volume: 1133, Issue:1 Topics: Amygdala; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Learning; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reward	2007
Tumor necrosis factor-alpha and its inducer inhibit morphine-induced rewarding effects and sensitization. Biological psychiatry, 2007, Sep-15, Volume: 62, Issue:6 Topics: Animals; Behavior, Animal; Conditioning, Operant; Dipeptides; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Reward; RNA, Messenger; Spatial Behavior; Substance Withdrawal Syndrome; Tumor Necrosis Factor-alpha	2007
Increased rewarding properties of morphine in perinatally protein-malnourished rats. Neuroscience, 2007, Dec-05, Volume: 150, Issue:2 Topics: Amygdala; Animals; Brain; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fetal Nutrition Disorders; Limbic System; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Prefrontal Cortex; Pregnancy; Protein Deficiency; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reward; Up-Regulation	2007
Galanin protects against behavioral and neurochemical correlates of opiate reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:8 Topics: Animals; Behavior, Animal; Blotting, Western; Brain Chemistry; Conditioning, Operant; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Galanin; Genotype; Mice; Mice, Knockout; Morphine; Morphine Dependence; Motor Activity; Narcotics; Reward; Signal Transduction	2008
Lesions of the medial prefrontal cortex prevent the acquisition but not reinstatement of morphine-induced conditioned place preference in mice. Neuroscience letters, 2008, Mar-05, Volume: 433, Issue:1 Topics: Animals; Behavior, Animal; Conditioning, Psychological; Denervation; Extinction, Psychological; Kainic Acid; Male; Mice; Morphine; Morphine Dependence; Narcotics; Neurotoxins; Prefrontal Cortex; Recurrence; Reinforcement Schedule; Reinforcement, Psychology; Reward	2008
Implication of endogenous beta-endorphin in the inhibition of the morphine-induced rewarding effect by the direct activation of spinal protein kinase C in mice. Neuroscience letters, 2008, Mar-05, Volume: 433, Issue:1 Topics: Animals; beta-Endorphin; Brain; Enzyme Activation; Enzyme Activators; Female; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Neural Inhibition; Pain; Protein Kinase C; Reward; Spinal Cord	2008
Autoantibodies against opioid or glutamate receptors are associated with changes in morphine reward and physical dependence in mice. Psychopharmacology, 2008, Volume: 197, Issue:4 Topics: Animals; Arousal; Autoantibodies; Avoidance Learning; Brain; Conditioning, Operant; Dose-Response Relationship, Drug; Down-Regulation; Grooming; Immunization; Male; Mice; Morphine; Morphine Dependence; Motivation; Motor Activity; Naloxone; Peptide Fragments; Receptors, AMPA; Receptors, Opioid, delta; Receptors, Opioid, mu; Reward; Social Environment; Stereotyped Behavior; Substance Withdrawal Syndrome	2008
Antagonism of muscarinic M1 receptors by dicyclomine inhibits the consolidation of morphine-associated contextual memory. Brain research bulletin, 2008, Jul-01, Volume: 76, Issue:4 Topics: Animals; Brain; Conditioning, Psychological; Dicyclomine; Dose-Response Relationship, Drug; Drug Interactions; Learning; Male; Memory; Mice; Morphine; Morphine Dependence; Muscarinic Antagonists; Narcotics; Receptor, Muscarinic M1; Reward; Time Factors	2008
Localization of the reward-relevant opiate receptors. NIDA research monograph, 1982, Volume: 41 Topics: Animals; Brain; Heroin Dependence; Humans; Male; Morphine Dependence; Rats; Receptors, Opioid; Reward; Self Administration	1982
Neural substrates of opiate reinforcement. Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6 Topics: Animals; Brain; Conditioning, Operant; Heroin Dependence; Humans; Limbic System; Mesencephalon; Morphine; Morphine Dependence; Neural Pathways; Periaqueductal Gray; Rats; Receptors, Dopamine; Receptors, Opioid; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Tegmentum Mesencephali	1983
Anatomically distinct opiate receptor fields mediate reward and physical dependence. Science (New York, N.Y.), 1984, May-04, Volume: 224, Issue:4648 Topics: Animals; Brain Chemistry; Humans; Microinjections; Morphine; Morphine Dependence; Naloxone; Rats; Receptors, Opioid; Reward	1984
Dissociation of the rewarding and physical dependence-producing properties of morphine. NIDA research monograph, 1983, Volume: 43 Topics: Animals; Humans; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Rats; Reward; Self Administration; Time Factors	1983
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature, 1996, Oct-31, Volume: 383, Issue:6603 Topics: Analgesics; Animals; Behavior, Animal; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Deletion; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Substance Withdrawal Syndrome	1996
[Effect of kynurenic acid on the intravenous self administration response acquisition in untrained rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 122, Issue:7 Topics: Animals; Depression, Chemical; Excitatory Amino Acid Antagonists; Infusions, Intravenous; Kynurenic Acid; Male; Morphine; Morphine Dependence; Rats; Rats, Wistar; Reward; Self Administration	1996
Intraaccumbens injections of substance P, morphine and amphetamine: effects on conditioned place preference and behavioral activity. Brain research, 1998, Apr-20, Volume: 790, Issue:1-2 Topics: Acute Disease; Amphetamine; Animals; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Dopamine; Grooming; Locomotion; Male; Morphine; Morphine Dependence; Motivation; Narcotics; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Spatial Behavior; Substance P; Sympathomimetics	1998
Morphine-induced suppression of saccharin intake is correlated with elevated corticosterone levels. Brain research, 2000, Apr-28, Volume: 863, Issue:1-2 Topics: Animals; Conditioning, Psychological; Corticosterone; Drug Interactions; Eating; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Self Administration; Stress, Physiological; Sweetening Agents; Taste	2000
Increased rewarding properties of morphine in dopamine-transporter knockout mice. The European journal of neuroscience, 2000, Volume: 12, Issue:5 Topics: Analgesia; Animals; Carrier Proteins; Choice Behavior; Conditioning, Operant; Crosses, Genetic; Cues; Dopamine; Dopamine Plasma Membrane Transport Proteins; Light; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Motor Activity; Nerve Tissue Proteins; Photic Stimulation; Reward	2000
The potential anti-addictive agent, 18-methoxycoronaridine, blocks the sensitized locomotor and dopamine responses produced by repeated morphine treatment. Brain research, 2000, May-02, Volume: 864, Issue:1 Topics: Animals; Dopamine; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Ibogaine; Microdialysis; Morphine; Morphine Dependence; Motor Activity; Narcotics; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Synaptic Transmission; Time Factors	2000
Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature, 2000, May-11, Volume: 405, Issue:6783 Topics: Animals; Cocaine; Conditioning, Classical; Corpus Striatum; Cyclic AMP; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurokinin-1; Receptors, Opioid, mu; Reward	2000
Effect of nociceptin/orphanin FQ on the rewarding properties of morphine. European journal of pharmacology, 2000, Sep-15, Volume: 404, Issue:1-2 Topics: Animals; Conditioning, Psychological; Drug Interactions; Male; Morphine; Morphine Dependence; Motor Activity; Nociceptin; Opioid Peptides; Rats; Rats, Wistar; Reward; Swimming; Vasodilator Agents	2000
Molecular evidence for the involvement of NR2B subunit containing N-methyl-D-aspartate receptors in the development of morphine-induced place preference. Neuroscience, 2000, Volume: 101, Issue:3 Topics: Animals; Antibodies; Behavior, Animal; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; N-Methylaspartate; Neurons; Prosencephalon; Receptors, N-Methyl-D-Aspartate; Reward; Seizures	2000
Involvement of protein kinase Cgamma isoform in morphine-induced reinforcing effects. Neuroscience, 2001, Volume: 103, Issue:2 Topics: Analgesics, Opioid; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Isoenzymes; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Protein Kinase C; Reinforcement, Psychology; Reward	2001
Mu opiate receptor gene dose effects on different morphine actions: evidence for differential in vivo mu receptor reserve. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:1 Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Conditioning, Psychological; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Mice; Mice, Knockout; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Nociceptors; Pain Measurement; Receptors, Opioid, mu; Reward; Self Administration	2001
Motivational state determines the functional role of the mesolimbic dopamine system in the mediation of opiate reward processes. Behavioural brain research, 2002, Feb-01, Volume: 129, Issue:1-2 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Conditioning, Operant; Dopamine; Flupenthixol; Limbic System; Lithium Chloride; Male; Microinjections; Morphine; Morphine Dependence; Motivation; Narcotics; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome	2002
Chronic morphine treatment modulates the extracellular levels of endogenous enkephalins in rat brain structures involved in opiate dependence: a microdialysis study. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Feb-01, Volume: 22, Issue:3 Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Cholecystokinin; Conditioning, Psychological; Drug Administration Schedule; Enkephalins; Extracellular Space; Hippocampus; Male; Microdialysis; Morphine; Morphine Dependence; Nucleus Accumbens; Opioid Peptides; Periaqueductal Gray; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome; Wakefulness	2002
Environment associated with morphine and experience of aggression modulate behaviors of postdependent mice. Brain research bulletin, 2002, Jan-15, Volume: 57, Issue:2 Topics: Agonistic Behavior; Animals; Convalescence; Environment; Housing, Animal; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Reward; Single-Blind Method; Substance Withdrawal Syndrome; Tremor	2002
Changes in morphine self-administration and morphine dependence after lesions of the caudate nucleus in rats. Psychopharmacologia, 1975, Volume: 41, Issue:3 Topics: Animals; Body Weight; Caudate Nucleus; Conditioning, Operant; Female; Humans; Morphine; Morphine Dependence; Naloxone; Rats; Reward; Stereotaxic Techniques; Substance Withdrawal Syndrome	1975
Some behavioural signs of morphine withdrawal blocked by condition stimuli. Nature, 1975, May-29, Volume: 255, Issue:5507 Topics: Animals; Behavior, Animal; Conditioning, Classical; Conflict, Psychological; Disease Models, Animal; Extinction, Psychological; Humans; Male; Morphine; Morphine Dependence; Naloxone; Punishment; Reinforcement Schedule; Reward; Substance Withdrawal Syndrome	1975
[Biological and learning-theory aspects of addictive behavior]. Schweizerische medizinische Wochenschrift, 1974, Apr-13, Volume: 104, Issue:15 Topics: Action Potentials; Animals; Anxiety; Avoidance Learning; Behavior; Cerebral Cortex; Defense Mechanisms; Dopamine; Electroencephalography; Evoked Potentials; Haplorhini; Humans; Learning; Morphine Dependence; Psychophysiology; Punishment; Rats; Reward; Social Behavior; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission	1974
Changes in sensitivity to the rewarding property of morphine following lesions of the medial forebrain bundle or caudate nucleus in rats. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2 Topics: Animals; Caudate Nucleus; Dose-Response Relationship, Drug; Female; Humans; Limbic System; Morphine; Morphine Dependence; Neural Pathways; Rats; Reward; Stereotaxic Techniques; Stimulation, Chemical; Time Factors	1974
Heroin addiction and the role of methadone in its treatment. Archives of general psychiatry, 1972, Volume: 26, Issue:4 Topics: Animals; Anxiety; Compulsive Behavior; Conditioning, Classical; Conditioning, Operant; Dogs; Drug Tolerance; Haplorhini; Heroin; Humans; Life Style; Methadone; Mice; Morphine Dependence; Motivation; Narcotic Antagonists; Rats; Recurrence; Reward; Substance Withdrawal Syndrome; Time Factors	1972
Conditioned nalorphine-induced abstinence changes: persistence in post morphine-dependent monkeys. Journal of the experimental analysis of behavior, 1970, Volume: 14, Issue:1 Topics: Animals; Behavior, Animal; Brain; Conditioning, Psychological; Feeding Behavior; Female; Haplorhini; Heart Rate; Humans; Injections, Intravenous; Male; Morphine Dependence; Nalorphine; Respiratory Function Tests; Reward; Salivation; Substance Withdrawal Syndrome; Temperature; Vomiting	1970