s,n,n'-tripropylthiocarbamate and Heroin Abuse

s,n,n'-tripropylthiocarbamate has been researched along with Heroin Abuse in 77 studies

Research

Studies (77)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (11.69)	18.7374
1990's	7 (9.09)	18.2507
2000's	26 (33.77)	29.6817
2010's	26 (33.77)	24.3611
2020's	9 (11.69)	2.80

Authors

Authors	Studies
Brand, M; Kriegler, J; Richter, F; Scherbaum, N; Wegener, S; Wegmann, E	1
Ferguson, SM; Nooney, MN; O'Neal, TJ; Thien, K	1
Rodríguez Mega, E	1
Haobam, R; Hijam, AC; Jaiswal, P; Koijam, AS; Mukhopadhyay, K; Rajamma, U; Singh, AS	1
Cai, Y; Liu, H; Liu, Y; Ma, B; Wang, F; Zhang, X; Zhou, W; Zhuang, D	1
Chen, J; Liu, J; Luo, J; Shao, Z; Tang, F; Wang, S; Yan, C; Yang, R; Yang, W; Yuan, K; Zhang, J	1
Fonville, L; Hayes, A; Herlinger, K; Hill, R; Lingford-Hughes, A; Nutt, D; Paterson, L	1
Fu, D; Hong, Q; Lai, M; Liu, H; Lou, Z; Zhou, W; Zhu, H; Zhuang, D	1
Bailey, CP; Heal, DJ; Palandri, J; Smith, SL; Wonnacott, S	1
Freiermuth, CE; Kisor, DF; McCorkle, ML; Sprague, JE	1
Haber, P; Morley, K; Moustafa, AA; Scherbaum, S; Underhill, D	1
Ahmed, SH; Brenot, V; Durand, A; Guillem, K	1
Biernacki, K; Labuschagne, I; McLennan, SN; Morton, P; Rendell, PG; Terrett, G	1
Caccamise, A; Dietz, DM; Martin, JA; Polanco, JJ; Sim, FJ; Stewart, AF; Thomas, SA; Viswanathan, R; Werner, CT	1
Chang, S; Chen, D; Fan, Y; Jing, R; Lu, L; Shi, J; Sun, Y; Yue, W; Zhang, D; Zhang, Y	1
Kaye, AD; McAnally, H; Remillard, D	1
Chen, J; Hu, F; Li, Q; Li, W; Li, Y; Liu, J; Liu, Y; Shi, H; Wang, W; Wang, Y; Wei, X; Ye, J; Zhu, J	1
Cadoni, C; Di Chiara, G; Espa, E; Fenu, S; Simola, N	1
Daglish, M; Dias, SR; Dissabandara, LO; Dodd, PR; Loxton, NJ; Stadlin, A	1
Chen, W; Fu, D; Lai, M; Sun, A; Zhang, HT; Zhou, W; Zhu, H; Zhuang, D	1
Cheng, J; González-Vallejo, C	1
Blum, K; Cronjé, FJ; Demetrovics, Z; Febo, M; Gold, MS; Han, D; Liu, Y; Oscar-Berman, M; Simpatico, T; Smolen, A; Wang, W; Wang, Y; Zhang, Y	1
Borgwardt, S; Denier, N; Huber, CG; Lang, UE; Magon, S; Radue, EW; Riecher-Rossler, A; Schmidt, A; Walter, M; Wiesbeck, GA	1
Chan, CC; Cheng, GL; Lee, TM; Liu, YP; So, KF; Zeng, H	1
Alexander, DN; Berg, A; Grigson, PS; Hajnal, A; Levenson, R; Morse, M; Tacelosky, DM	1
Greenwald, MK; Lister, JJ; Lundahl, LH; Stoltman, JJ; Woodcock, EA	1
Bixler, G; Freeman, WM; Grigson, PS; Imperio, CG; McFalls, AJ; Vrana, KE	1
Colechio, EM; Freeman, WM; Grigson, PS; Imperio, CG; Masser, DR; McFalls, AJ; Vrana, KE	1
Barbier, E; Bi, GH; Chiu, YT; Feng, B; He, Y; Liu-Chen, LY; Wang, JB; Wang, XF; Xi, ZX; Zhan, J; Zhang, HY	1
Ho, A; Kreek, MJ; Landthaler, M; Schlussman, SD; Tuschl, T; Yuferov, V; Zhang, Y	1
El Rawas, R; Jaber, M; Lardeux, V; Solinas, M; Thiriet, N	1
Allen, NB; Kettle, JW; Lubman, DI; Mackenzie, T; Scaffidi, A; Simmons, JG; Yücel, M	1
Allison, DW; Bufalino, MR; Clarke, L; Hansen, DM; Razavi, R; Steffensen, SC; Ting-A Kee, R; van der Kooy, D; Vargas-Perez, H; Walton, CH	1
Bossert, JM; Nair, SG; Pickens, CL; Shaham, Y; Wihbey, KA	1
Enoch, MA; Goldman, D; Gorodetsky, E; Hodgkinson, C; Roy, A	1
Allen, C; Blum, K; Bowirrat, A; Downs, BW; Gant, C; Manka, D; Manka, M; Miller, DK; Miller, M; Smolen, A; Stevens, E; Stokes, S; Yeldandi, S	1
Bannon, MJ; Blythe, J; Jia, H; Kapatos, G; Lipovich, L; Michelhaugh, SK	1
Adelson, M; Peles, E; Sason, A; Schreiber, S	1
Edwards, S; Koob, GF; Misra, KK; Park, PE; Schlosburg, JE; Schulteis, G; Vendruscolo, LF; Wee, S	1
Hou, H; Tian, M; Zhang, H	1
Leri, F; Stewart, J	1
Lingford-Hughes, A; Nutt, D	1
Kirby, KN; Petry, NM	1
Lai, M; Liu, H; Tang, S; Yang, G; Zhang, F; Zhou, W	1
Greenwald, MK	1
Bornovalova, MA; Daughters, SB; Hernandez, GD; Lejuez, CW; Richards, JB	1
Gonsai, K; Gonzalez, G; Kosten, TR; Martell, B; Oliveto, A; Petry, N; Poling, J; Sofuoglu, M	1
Chen, SA; Kenny, PJ; Kitamura, O; Koob, GF; Markou, A	1
De Vry, J; Magalas, Z; Tzschentke, TM	1
Keiflin, R; Lenoir, M	1
Barnett, P; Batki, SL; Delucchi, KL; Gruber, V; Hall, S; Haug, NA; Kletter, E; Sorensen, JL; Tulsky, JP	1
Kalivas, PW; Lai, M; Liu, H; Tang, S; Zhang, F; Zhou, W; Zhu, H	1
Hood, S; Sorge, RE; Stewart, J	1
Epstein, DH; Ghitza, UE; Lin, JL; Preston, KL; Schmittner, J; Vahabzadeh, M	1
Bossert, JM; Koya, E; Poles, GC; Shaham, Y; Wihbey, KA	1
Alvarez-Jaimes, L; Parsons, LH; Polis, I	1
Epstein, DH; Ghitza, UE; Preston, KL	1
Bozarth, MA; Wise, RA	2
Comings, DE; Gade, R; Johnson, P; MacMurray, J; Muhleman, D; Saucier, G; Verde, R	1
Kiyatkin, EA; Rebec, GV	1
Chutuape, MA; Silverman, K; Stitzer, ML	1
Bickel, WK; Kirby, KN; Petry, NM	1
Bearn, J; Dolan, RJ; Frackowiak, RS; Friston, KJ; Morris, J; Sell, LA	1
Collins, ED; Comer, SD; Fischman, MW; MacArthur, RB	1
Epstein, DH; Preston, KL; Umbricht, A	1
Highfield, D; Shaham, Y; Shalev, U; Yap, J	1
Dickinson, A; Everitt, BJ; Hutcheson, DM; Robbins, TW	1
Casini, A; D'Este, L; Pontieri, FE; Renda, TG; Scontrini, A	1
Ottomanelli, GA	1
Eriksson, JH; Götestam, KG; Melin, L; Ost, LG	1
Kauders, F; Schecter, A	1
Hubner, CB; Kornetsky, C	1
De Vry, J; Donselaar, I; Van Ree, JM	1
Van Ree, JM	1
Caffrey, B; Capel, WC	1
Angle, HV; Knowles, RR; Marrazzi, AS; Sletten, IW	1

Reviews

4 review(s) available for s,n,n'-tripropylthiocarbamate and Heroin Abuse

Article	Year
Systematic review of Pharmacogenomics Knowledgebase evidence for pharmacogenomic links to the dopamine reward pathway for heroin dependence. Pharmacogenomics, 2021, Volume: 22, Issue:13 Topics: Animals; Biomarkers; Dopamine; Heroin Dependence; Humans; Knowledge Bases; Neural Pathways; Pharmacogenetics; Reward	2021
Acute intravenous synaptamine complex variant KB220™ "normalizes" neurological dysregulation in patients during protracted abstinence from alcohol and opiates as observed using quantitative electroencephalographic and genetic analysis for reward polymorph Postgraduate medicine, 2010, Volume: 122, Issue:6 Topics: Alcoholism; Alleles; Dopamine Agonists; Electroencephalography; Follow-Up Studies; Heroin Dependence; Humans; Injections, Intravenous; Male; Pilot Projects; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Receptors, Dopamine D2; Reward; Risk Assessment; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult	2010
Positron emission tomography molecular imaging of dopaminergic system in drug addiction. Anatomical record (Hoboken, N.J. : 2007), 2012, Volume: 295, Issue:5 Topics: Animals; Behavior, Addictive; Brain; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Heroin Dependence; Humans; Neural Pathways; Neuroimaging; Positron-Emission Tomography; Receptors, Dopamine; Reinforcement, Psychology; Reward; Signal Transduction; Substance-Related Disorders; Time Factors	2012
Neurobiology of addiction and implications for treatment. The British journal of psychiatry : the journal of mental science, 2003, Volume: 182 Topics: Behavior, Addictive; Dopamine; Heroin Dependence; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders	2003

Trials

10 trial(s) available for s,n,n'-tripropylthiocarbamate and Heroin Abuse

Article	Year
rsfMRI effects of KB220Z™ on neural pathways in reward circuitry of abstinent genotyped heroin addicts. Postgraduate medicine, 2015, Volume: 127, Issue:2 Topics: Adult; Algorithms; Brain; Brain Chemistry; Catecholamines; Cross-Over Studies; Dopamine Agonists; Electroencephalography; Female; Functional Neuroimaging; Genotyping Techniques; Heroin Dependence; Humans; Image Processing, Computer-Assisted; Male; Monoamine Oxidase; Neprilysin; Neural Pathways; Pilot Projects; Reward; Substance Withdrawal Syndrome; Young Adult	2015
Heroin and cocaine abusers have higher discount rates for delayed rewards than alcoholics or non-drug-using controls. Addiction (Abingdon, England), 2004, Volume: 99, Issue:4 Topics: Adult; Alcoholism; Choice Behavior; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Impulsive Behavior; Male; Middle Aged; Motivation; Reward; Surveys and Questionnaires; Time Factors	2004
Opioid craving and seeking behavior in physically dependent volunteers: effects of acute withdrawal and drug reinforcement opportunity. Experimental and clinical psychopharmacology, 2005, Volume: 13, Issue:1 Topics: Adult; Conditioning, Operant; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Heroin Dependence; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; Narcotics; Psychiatric Status Rating Scales; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Surveys and Questionnaires	2005
Six-month trial of bupropion with contingency management for cocaine dependence in a methadone-maintained population. Archives of general psychiatry, 2006, Volume: 63, Issue:2 Topics: Adult; Behavior Therapy; Bupropion; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Comorbidity; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Heroin Dependence; Humans; Male; Methadone; Placebos; Psychiatric Status Rating Scales; Reward; Substance Abuse Detection	2006
Voucher reinforcement improves medication adherence in HIV-positive methadone patients: a randomized trial. Drug and alcohol dependence, 2007, Apr-17, Volume: 88, Issue:1 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Monitoring; Female; Heroin Dependence; HIV Infections; Humans; Male; Methadone; Narcotics; Outcome Assessment, Health Care; Patient Compliance; Reward; Time Factors; Token Economy	2007
Randomized trial of prize-based reinforcement density for simultaneous abstinence from cocaine and heroin. Journal of consulting and clinical psychology, 2007, Volume: 75, Issue:5 Topics: Adult; Cocaine-Related Disorders; Comorbidity; Double-Blind Method; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Motivation; Narcotics; Reinforcement Schedule; Reward; Software; Therapy, Computer-Assisted; Token Economy	2007
Contingency management reduces injection-related HIV risk behaviors in heroin and cocaine using outpatients. Addictive behaviors, 2008, Volume: 33, Issue:4 Topics: Adolescent; Adult; Aged; Cocaine-Related Disorders; Counseling; Female; Heroin Dependence; HIV Infections; Humans; Male; Methadone; Middle Aged; Narcotics; Reward; Risk Factors; Substance Abuse Treatment Centers; Substance Abuse, Intravenous	2008
Use of methadone take-home contingencies with persistent opiate and cocaine abusers. Journal of substance abuse treatment, 1999, Volume: 16, Issue:1 Topics: Adult; Analgesics, Opioid; Analysis of Variance; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Male; Methadone; Monitoring, Physiologic; Reward; Single-Blind Method	1999
Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls. Journal of experimental psychology. General, 1999, Volume: 128, Issue:1 Topics: Adult; Analysis of Variance; Choice Behavior; Heroin Dependence; Humans; Impulsive Behavior; Models, Psychological; Reward	1999
Methadone dose increase and abstinence reinforcement for treatment of continued heroin use during methadone maintenance. Archives of general psychiatry, 2000, Volume: 57, Issue:4 Topics: Adult; Behavior Therapy; Behavior, Addictive; Cocaine-Related Disorders; Combined Modality Therapy; Crime; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Heroin Dependence; Humans; Life Style; Male; Methadone; Narcotics; Reward; Substance Abuse Detection; Substance Abuse Treatment Centers; Treatment Outcome	2000

Other Studies

63 other study(ies) available for s,n,n'-tripropylthiocarbamate and Heroin Abuse

Article	Year
Decision making of individuals with heroin addiction receiving opioid maintenance treatment compared to early abstinent users. Drug and alcohol dependence, 2019, 12-01, Volume: 205 Topics: Adult; Analgesics, Opioid; Craving; Decision Making; Female; Gambling; Heroin; Heroin Dependence; Humans; Male; Middle Aged; Opiate Substitution Treatment; Reward; Secondary Prevention; Temperance	2019
Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but not low-risk rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:8 Topics: Animals; Cues; Extinction, Psychological; Heroin; Heroin Dependence; Nucleus Accumbens; Rats; Reward; Self Administration	2020
The psychiatrist at the centre of the opioid crisis. Nature, 2020, Volume: 580, Issue:7802 Topics: Alcoholism; Cocaine-Related Disorders; Dopamine; Drug Overdose; Heroin Dependence; History, 20th Century; History, 21st Century; Humans; Marijuana Abuse; Methadone; Methamphetamine; Naloxone; National Institutes of Health (U.S.); Neurosciences; Opioid-Related Disorders; Positron-Emission Tomography; Prefrontal Cortex; Psychiatry; Reward; Socioeconomic Factors; United States	2020
Association of Dopamine Transporter Gene with Heroin Dependence in an Indian Subpopulation from Manipur. Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:1 Topics: 3' Untranslated Regions; Adolescent; Adult; Alleles; Asian People; Case-Control Studies; Computational Biology; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Ethnicity; Female; Genetic Markers; Haplotypes; Heroin Dependence; Humans; India; Introns; Linkage Disequilibrium; Male; Middle Aged; Minisatellite Repeats; Nerve Net; Polymorphism, Single Nucleotide; Reward; Young Adult	2021
Huperzine A inhibits heroin-seeking behaviors induced by cue or heroin priming in rats. Neuroreport, 2020, 08-05, Volume: 31, Issue:11 Topics: Alkaloids; Animals; Behavior, Animal; Cholinesterase Inhibitors; Cues; Drug-Seeking Behavior; Heroin; Heroin Dependence; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Sesquiterpenes	2020
Novel circuit biomarker of impulsivity and craving in male heroin-dependent individuals. Drug and alcohol dependence, 2021, 02-01, Volume: 219 Topics: Adult; Behavior, Addictive; Biomarkers; Brain; Brain Mapping; Case-Control Studies; Cerebral Cortex; Corpus Striatum; Craving; Diffusion Tensor Imaging; Gyrus Cinguli; Heroin; Heroin Dependence; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Male; Middle Aged; Opioid-Related Disorders; Reward	2021
Functional evaluation of NK Drug and alcohol dependence, 2021, 04-01, Volume: 221 Topics: Adult; Amygdala; Analgesics, Opioid; Brain; Brain Mapping; Conditioning, Psychological; Craving; Cues; Female; Heroin; Heroin Dependence; Humans; Magnetic Resonance Imaging; Male; Neurokinin-1 Receptor Antagonists; Opiate Alkaloids; Opioid-Related Disorders; Receptors, Neurokinin-1; Reward; Young Adult	2021
Akt and its phosphorylation in nucleus accumbens mediate heroin-seeking behavior induced by cues in rats. Addiction biology, 2021, Volume: 26, Issue:5 Topics: Animals; Cues; Drug-Seeking Behavior; Heroin; Heroin Dependence; Male; Nucleus Accumbens; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Substance Withdrawal Syndrome	2021
Contrasting effects of the α7 nicotinic receptor antagonist methyllycaconitine in different rat models of heroin reinstatement. Journal of psychopharmacology (Oxford, England), 2021, Volume: 35, Issue:10 Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Addictive; Conditioning, Psychological; Cues; Drug-Seeking Behavior; Extinction, Psychological; Heroin; Heroin Dependence; Male; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration	2021
Biased and less sensitive: A gamified approach to delay discounting in heroin addiction. Journal of clinical and experimental neuropsychology, 2018, Volume: 40, Issue:2 Topics: Adult; Decision Making; Delay Discounting; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Personality Assessment; Reference Values; Reward; Video Games; Virtual Reality	2018
Neuronal representation of individual heroin choices in the orbitofrontal cortex. Addiction biology, 2018, Volume: 23, Issue:3 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Choice Behavior; Conditioning, Psychological; Heroin; Heroin Dependence; Neurons; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Wistar; Reward; Self Administration	2018
Decision-making, somatic markers and emotion processing in opiate users. Psychopharmacology, 2018, Volume: 235, Issue:1 Topics: Adult; Decision Making; Drug Users; Emotions; Female; Galvanic Skin Response; Gambling; Heroin Dependence; Humans; Male; Middle Aged; Opiate Substitution Treatment; Punishment; Reward	2018
A Novel Role for Oligodendrocyte Precursor Cells (OPCs) and Sox10 in Mediating Cellular and Behavioral Responses to Heroin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:6 Topics: Animals; DNA Helicases; Drug-Seeking Behavior; Gene Expression Regulation; Heroin; Heroin Dependence; Male; Motivation; Narcotics; Nuclear Proteins; Oligodendrocyte Precursor Cells; Prefrontal Cortex; Rats, Sprague-Dawley; Reward; Self Administration; SOXE Transcription Factors; Transcription Factors	2018
GABRA2 rs279858-linked variants are associated with disrupted structural connectome of reward circuits in heroin abusers. Translational psychiatry, 2018, 07-30, Volume: 8, Issue:1 Topics: Adult; Behavior, Addictive; Case-Control Studies; China; Connectome; Diffusion Tensor Imaging; Gene Regulatory Networks; Heroin Dependence; Humans; Linear Models; Male; Polymorphism, Single Nucleotide; Receptors, GABA-A; Reward	2018
Oxycodone's Unparalleled Addictive Potential: Is it Time for a Moratorium? Current pain and headache reports, 2019, Feb-28, Volume: 23, Issue:2 Topics: Adult; Alaska; Analgesics, Opioid; Cross-Sectional Studies; Dopamine Agents; Female; Heroin Dependence; Humans; Male; Middle Aged; Opioid-Related Disorders; Oxycodone; Pain Management; Prescription Drug Misuse; Reward	2019
The polymorphism of dopamine D2 receptor TaqIA gene is associated with brain response to drug cues in male heroin-dependent individuals during methadone maintenance treatment. Drug and alcohol dependence, 2019, 05-01, Volume: 198 Topics: Adult; Alleles; Analgesics, Opioid; Brain; Craving; Cues; Heroin; Heroin Dependence; Humans; Magnetic Resonance Imaging; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Pharmacogenomic Variants; Polymorphism, Genetic; Receptors, Dopamine D2; Recurrence; Reward	2019
Strain dependence of adolescent Cannabis influence on heroin reward and mesolimbic dopamine transmission in adult Lewis and Fischer 344 rats. Addiction biology, 2015, Volume: 20, Issue:1 Topics: Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Dopamine; Dronabinol; Heroin; Heroin Dependence; Male; Microdialysis; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reward; Synaptic Transmission	2015
Dependent heroin use and associated risky behaviour: the role of rash impulsiveness and reward sensitivity. Addictive behaviors, 2014, Volume: 39, Issue:1 Topics: Adult; Case-Control Studies; Criminals; Heroin Dependence; Humans; Impulsive Behavior; Logistic Models; Male; Middle Aged; Multivariate Analysis; Personality; Personality Inventory; Reward; Risk-Taking; Sexual Behavior; Sri Lanka; Young Adult	2014
The phosphodiesterase-4 inhibitor rolipram attenuates heroin-seeking behavior induced by cues or heroin priming in rats. The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:9 Topics: Animals; Conditioning, Operant; CREB-Binding Protein; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Heroin; Heroin Dependence; Male; Narcotics; Phosphodiesterase 4 Inhibitors; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Rolipram; Self Administration	2014
Hyperbolic discounting: value and time processes of substance abusers and non-clinical individuals in intertemporal choice. PloS one, 2014, Volume: 9, Issue:11 Topics: Adult; Algorithms; Area Under Curve; Choice Behavior; Drug Users; Female; Heroin Dependence; Humans; Impulsive Behavior; Male; Models, Psychological; Models, Statistical; Reward; Substance-Related Disorders; Time Perception	2014
Increased functional connectivity in the resting-state basal ganglia network after acute heroin substitution. Translational psychiatry, 2015, Mar-24, Volume: 5 Topics: Adult; Basal Ganglia; Brain; Brain Mapping; Cross-Over Studies; Double-Blind Method; Female; Heroin; Heroin Dependence; Humans; Magnetic Resonance Imaging; Male; Morphine; Opiate Substitution Treatment; Rest; Reward	2015
Neurobiological underpinnings of sensation seeking trait in heroin abusers. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:11 Topics: Adult; Alcohol Drinking; Brain; Brain Mapping; Heroin Dependence; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Organ Size; Personality; Personality Tests; Rest; Reward; Smoking	2015
Low expression of D2R and Wntless correlates with high motivation for heroin. Behavioral neuroscience, 2015, Volume: 129, Issue:6 Topics: Animals; Behavior, Addictive; Drug-Seeking Behavior; Gene Expression; Heroin; Heroin Dependence; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Motivation; Narcotics; Nucleus Accumbens; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; Reward; Self Administration	2015
Heroin delay discounting: Modulation by pharmacological state, drug-use impulsivity, and intelligence. Experimental and clinical psychopharmacology, 2015, Volume: 23, Issue:6 Topics: Adult; Delay Discounting; Emotional Intelligence; Female; Heroin; Heroin Dependence; Humans; Impulsive Behavior; Intelligence; Male; Middle Aged; Reward; Substance Withdrawal Syndrome; Young Adult	2015
Reward devaluation and heroin escalation is associated with differential expression of CRF signaling genes. Brain research bulletin, 2016, Volume: 123 Topics: Animals; Corticotropin-Releasing Hormone; Cues; Heroin; Heroin Dependence; Hippocampus; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Reward; Saccharin; Self Administration; Ventral Tegmental Area	2016
Assessment of individual differences in the rat nucleus accumbens transcriptome following taste-heroin extended access. Brain research bulletin, 2016, Volume: 123 Topics: Animals; Brain; Conditioning, Operant; Cues; Heroin; Heroin Dependence; Individuality; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Self Administration; Taste; Taste Perception; Transcriptome	2016
T394A Mutation at the μ Opioid Receptor Blocks Opioid Tolerance and Increases Vulnerability to Heroin Self-Administration in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 10-05, Volume: 36, Issue:40 Topics: Analgesia; Analgesics, Opioid; Animals; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Heroin Dependence; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Mutation; Pain Measurement; Phosphorylation; Point Mutation; Receptors, Opioid, mu; Reward; Self Administration	2016
Mu opioid receptor knockdown in the substantia nigra/ventral tegmental area by synthetic small interfering RNA blocks the rewarding and locomotor effects of heroin. Neuroscience, 2009, Jan-23, Volume: 158, Issue:2 Topics: Analysis of Variance; Animals; Autoradiography; Heroin; Heroin Dependence; Locomotion; Male; Mice; Mice, Inbred C57BL; Reaction Time; Receptors, Opioid, mu; Reward; RNA, Small Interfering; Substantia Nigra; Time Factors; Ventral Tegmental Area	2009
Environmental enrichment decreases the rewarding but not the activating effects of heroin. Psychopharmacology, 2009, Volume: 203, Issue:3 Topics: Animals; Behavior, Animal; Conditioning, Psychological; Environment; Heroin; Heroin Dependence; Male; Mice; Mice, Inbred C57BL; Reward	2009
Responsiveness to drug cues and natural rewards in opiate addiction: associations with later heroin use. Archives of general psychiatry, 2009, Volume: 66, Issue:2 Topics: Adult; Affective Symptoms; Alcoholism; Arousal; Attention; Cerebral Cortex; Comorbidity; Cues; Electromyography; Emotions; Event-Related Potentials, P300; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Middle Aged; Motivation; Narcotics; Recurrence; Reflex, Startle; Reward; Risk Factors; Young Adult	2009
Ventral tegmental area BDNF induces an opiate-dependent-like reward state in naive rats. Science (New York, N.Y.), 2009, Jun-26, Volume: 324, Issue:5935 Topics: Animals; Bicuculline; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Dopamine; Dopamine Antagonists; Flupenthixol; GABA Agonists; GABA Antagonists; Heroin Dependence; Male; Morphine; Muscimol; Opioid-Related Disorders; Rats; Rats, Wistar; Receptors, GABA-A; Reward; RNA, Messenger; Signal Transduction; Substance Withdrawal Syndrome; Ventral Tegmental Area	2009
Role of dopamine D(1)-family receptors in dorsolateral striatum in context-induced reinstatement of heroin seeking in rats. Psychopharmacology, 2009, Volume: 206, Issue:1 Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Conditioning, Psychological; Corpus Striatum; Disease Models, Animal; Extinction, Psychological; Heroin; Heroin Dependence; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Reinforcement Schedule; Reward; Secondary Prevention; Self Administration	2009
Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence. Molecular psychiatry, 2011, Volume: 16, Issue:11 Topics: Adult; Alcoholism; Alleles; Black or African American; Cocaine-Related Disorders; Comorbidity; Dopamine; Genetic Predisposition to Disease; Genotype; Haplotypes; Heroin Dependence; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Serotonin, 5-HT3; Reward; Serotonin; Serotonin Plasma Membrane Transport Proteins	2011
Mining Affymetrix microarray data for long non-coding RNAs: altered expression in the nucleus accumbens of heroin abusers. Journal of neurochemistry, 2011, Volume: 116, Issue:3 Topics: Analgesics, Opioid; Brain Chemistry; Data Mining; Gene Expression Regulation; Genetic Markers; Heroin; Heroin Dependence; Humans; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Reward; RNA, Untranslated; Up-Regulation	2011
Earning "take-home" privileges and long-term outcome in a methadone maintenance treatment program. Journal of addiction medicine, 2011, Volume: 5, Issue:2 Topics: Adult; Analgesics, Opioid; Female; Heroin Dependence; Humans; Male; Methadone; Motivation; Patient Compliance; Prospective Studies; Reinforcement Schedule; Reward; Substance Abuse Detection; Substance Abuse Treatment Centers; Treatment Outcome; Young Adult	2011
Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: alleviation by CRF₁ receptor antagonism. Neuropharmacology, 2012, Volume: 62, Issue:2 Topics: Alcoholism; Animals; Cocaine; Cocaine-Related Disorders; Heroin; Heroin Dependence; Hyperalgesia; Male; Pain Perception; Pain Threshold; Physical Stimulation; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reward; Self Administration	2012
The consequences of different "lapses" on relapse to heroin seeking in rats. Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:4 Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Operant; Discrimination Learning; Electric Stimulation; Electroshock; Extinction, Psychological; Heroin; Heroin Dependence; Male; Models, Animal; Photic Stimulation; Rats; Rats, Long-Evans; Recurrence; Reward; Self Administration; Time Factors	2002
Low dose of heroin inhibits drug-seeking elicited by cues after prolonged withdrawal from heroin self-administration in rats. Neuroreport, 2004, Mar-22, Volume: 15, Issue:4 Topics: Animals; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Heroin; Heroin Dependence; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Risk Factors; Self Administration; Substance Withdrawal Syndrome; Time Factors	2004
Differences in impulsivity and risk-taking propensity between primary users of crack cocaine and primary users of heroin in a residential substance-use program. Experimental and clinical psychopharmacology, 2005, Volume: 13, Issue:4 Topics: Age Factors; Analysis of Variance; Behavioral Research; Cocaine-Related Disorders; Crack Cocaine; District of Columbia; Female; Heroin; Heroin Dependence; Humans; Impulsive Behavior; Male; Residential Treatment; Reward; Risk-Taking; Sex Factors; Surveys and Questionnaires; Urban Population	2005
Conditioned withdrawal drives heroin consumption and decreases reward sensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, May-31, Volume: 26, Issue:22 Topics: Animals; Conditioning, Classical; Disease Models, Animal; Electric Stimulation; Heroin; Heroin Dependence; Male; Naloxone; Narcotic Antagonists; Rats; Reward; Self Stimulation; Substance Withdrawal Syndrome	2006
Effects of venlafaxine and desipramine on heroin-induced conditioned place preference in the rat. Addiction biology, 2006, Volume: 11, Issue:1 Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Association Learning; Choice Behavior; Conditioning, Classical; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Heroin Dependence; Injections, Intraperitoneal; Male; Premedication; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Social Environment; Substance Abuse, Intravenous; Venlafaxine Hydrochloride	2006
Heroin addiction: anticipating the reward of heroin or the agony of withdrawal? The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-06, Volume: 26, Issue:36 Topics: Animals; Conditioning, Classical; Disease Models, Animal; Electric Stimulation; Heroin; Heroin Dependence; Male; Naloxone; Narcotic Antagonists; Rats; Reward; Self Stimulation; Substance Withdrawal Syndrome	2006
Role of acetylcholine transmission in nucleus accumbens and ventral tegmental area in heroin-seeking induced by conditioned cues. Neuroscience, 2007, Feb-23, Volume: 144, Issue:4 Topics: Acetylcholine; Animals; Cholinergic Fibers; Cholinesterase Inhibitors; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Exploratory Behavior; Heroin; Heroin Dependence; Learning; Male; Microinjections; Muscarinic Antagonists; Narcotics; Neural Pathways; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Synaptic Transmission; Ventral Tegmental Area	2007
Chronic buprenorphine reduces the response to sucrose-associated cues in non food-deprived rats. Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:3 Topics: Animals; Buprenorphine; Cocaine-Related Disorders; Cues; Eating; Extinction, Psychological; Heroin Dependence; Male; Narcotic Antagonists; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration; Sucrose	2007
Differential effects of blockade of dopamine D1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and discrete cues. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Nov-14, Volume: 27, Issue:46 Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Antagonists; Extinction, Psychological; Heroin Dependence; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Reward; Secondary Prevention; Self Administration	2007
Attenuation of cue-induced heroin-seeking behavior by cannabinoid CB1 antagonist infusions into the nucleus accumbens core and prefrontal cortex, but not basolateral amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:10 Topics: Amygdala; Animals; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Heroin; Heroin Dependence; Male; Motivation; Narcotics; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Reward; Rimonabant	2008
Localization of the reward-relevant opiate receptors. NIDA research monograph, 1982, Volume: 41 Topics: Animals; Brain; Heroin Dependence; Humans; Male; Morphine Dependence; Rats; Receptors, Opioid; Reward; Self Administration	1982
Neural substrates of opiate reinforcement. Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6 Topics: Animals; Brain; Conditioning, Operant; Heroin Dependence; Humans; Limbic System; Mesencephalon; Morphine; Morphine Dependence; Neural Pathways; Periaqueductal Gray; Rats; Receptors, Dopamine; Receptors, Opioid; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Tegmentum Mesencephali	1983
Cannabinoid receptor gene (CNR1): association with i.v. drug use. Molecular psychiatry, 1997, Volume: 2, Issue:2 Topics: Administration, Inhalation; Administration, Oral; Adult; Alcoholism; Alleles; Amphetamines; Cocaine; Comorbidity; Disease Susceptibility; Evoked Potentials; Female; Gene Frequency; Genotype; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Male; Middle Aged; Receptors, Cannabinoid; Receptors, Drug; Reward; Risk Factors; Smoking; Substance Abuse, Intravenous; Substance-Related Disorders; Trinucleotide Repeats	1997
Activity of presumed dopamine neurons in the ventral tegmental area during heroin self-administration. Neuroreport, 1997, Jul-28, Volume: 8, Issue:11 Topics: Animals; Dopamine; Heroin; Heroin Dependence; Limbic System; Male; Neurons; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Tegmentum Mesencephali; Time Factors; Videotape Recording	1997
Activation of reward circuitry in human opiate addicts. The European journal of neuroscience, 1999, Volume: 11, Issue:3 Topics: Adult; Brain Chemistry; Brain Stem; gamma-Aminobutyric Acid; Heroin; Heroin Dependence; Humans; Interneurons; Male; Mesencephalon; Narcotics; Neural Pathways; Pain Measurement; Parietal Lobe; Photic Stimulation; Reward; Tomography, Emission-Computed	1999
Comparison of intravenous and intranasal heroin self-administration by morphine-maintained humans. Psychopharmacology, 1999, Volume: 143, Issue:4 Topics: Administration, Inhalation; Administration, Oral; Adult; Analysis of Variance; Choice Behavior; Drug Administration Schedule; Female; Hemodynamics; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Narcotics; Reward; Self Administration; Task Performance and Analysis	1999
Stress and relapse to drug seeking in rats: studies on the generality of the effect. Psychopharmacology, 2000, Volume: 150, Issue:3 Topics: Animals; Electric Stimulation; Electroshock; Food Deprivation; Heroin; Heroin Dependence; Male; Narcotics; Rats; Rats, Long-Evans; Reward; Septum of Brain; Stress, Psychological; Substance-Related Disorders	2000
The role of withdrawal in heroin addiction: enhances reward or promotes avoidance? Nature neuroscience, 2001, Volume: 4, Issue:9 Topics: Animals; Avoidance Learning; Behavior, Animal; Heroin; Heroin Dependence; Male; Rats; Rats, Inbred Strains; Reward; Self Administration; Substance Withdrawal Syndrome	2001
Heroin sensitization as mapped by c-Fos immunoreactivity in the rat striatum. Brain research, 2002, Apr-19, Volume: 933, Issue:2 Topics: Animals; Basal Ganglia; Behavior, Animal; Brain Mapping; Cell Count; Dopamine; Drug Tolerance; Heroin; Heroin Dependence; Immunohistochemistry; Male; Motor Activity; Narcotics; Neostriatum; Neural Pathways; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reward; Up-Regulation	2002
Follow-up of a token economy applied to civilly committed narcotic addicts. The International journal of the addictions, 1976, Volume: 11, Issue:5 Topics: Adolescent; Adult; Aftercare; Eligibility Determination; Evaluation Studies as Topic; Forensic Psychiatry; Heroin Dependence; Humans; Male; MMPI; New York City; Rehabilitation Centers; Reward; Token Economy	1976
A token economy treatment of drug addiction. Behaviour research and therapy, 1975, Volume: 13, Issue:2-3 Topics: Adolescent; Adult; Amphetamines; Female; Heroin Dependence; Humans; Male; Reinforcement Schedule; Reward; Substance-Related Disorders; Sweden; Token Economy	1975
Methadone and l-alpha-acetylmethadol in a treatment program in Brooklyn. The American journal of drug and alcohol abuse, 1975, Volume: 2, Issue:3-4 Topics: Adult; Aged; Consumer Behavior; Drug Evaluation; Employment; Ethnicity; Heroin Dependence; Hostility; Humans; Male; Methadone; Methadyl Acetate; Middle Aged; New York City; Patient Dropouts; Reward; United States; United States Food and Drug Administration	1975
Heroin, 6-acetylmorphine and morphine effects on threshold for rewarding and aversive brain stimulation. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2 Topics: Animals; Aversive Therapy; Brain; Electric Stimulation; Heroin; Heroin Dependence; Male; Morphine; Morphine Derivatives; Rats; Reward	1992
Intraventricular self-administration of heroin in the rat: reward seems dissociated from analgesia and physical dependence. European journal of pharmacology, 1989, Feb-14, Volume: 161, Issue:1 Topics: Analgesics; Animals; Heroin; Heroin Dependence; Injections, Intraventricular; Male; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Reward; Self Administration	1989
Role of pituitary and related neuropeptides in alcoholism and pharmacodependence. Progress in neuro-psychopharmacology & biological psychiatry, 1986, Volume: 10, Issue:2 Topics: Adrenocorticotropic Hormone; Alcoholism; Animals; Arginine Vasopressin; beta-Endorphin; Brain; Endorphins; Haplorhini; Heroin Dependence; Humans; Melanocyte-Stimulating Hormones; Naltrexone; Neurotransmitter Agents; Peptides; Pituitary Gland; Rats; Reinforcement, Psychology; Reward; Substance-Related Disorders	1986
"Faking good" as a problem in comparative studies of heroin addicts. Psychological reports, 1974, Volume: 35, Issue:2 Topics: Attitude; Authoritarianism; Frustration; Goals; Heroin Dependence; Humans; Psychological Tests; Reward; Social Desirability; Social Perception; Stress, Psychological	1974
Method for self-administering methadone by the heroin addict. The International journal of the addictions, 1973, Volume: 8, Issue:3 Topics: Administration, Oral; Adult; Conditioning, Operant; Evaluation Studies as Topic; Female; Heroin Dependence; Humans; Male; Methadone; Methods; Reinforcement Schedule; Reward; Substance Withdrawal Syndrome	1973