Page last updated: 2024-08-21

s,n,n'-tripropylthiocarbamate and Disease Models, Animal

s,n,n'-tripropylthiocarbamate has been researched along with Disease Models, Animal in 560 studies

Research

Studies (560)

TimeframeStudies, this research(%)All Research%
pre-19909 (1.61)18.7374
1990's12 (2.14)18.2507
2000's134 (23.93)29.6817
2010's329 (58.75)24.3611
2020's76 (13.57)2.80

Authors

AuthorsStudies
Abbate-Daga, G; Aspesi, D; Farinetti, A; Gotti, S; Marraudino, M; Marzola, E; Morgan, GSK1
Asth, L; de Barros, JLVM; de Miranda, AS; Machado, CA; Moreira, FA; Oliveira, BDS; Rosa, MLP; Teixeira, AL; Toscano, ECB1
De Biasi, M; Feinn, R; Kranzler, HR; Perez, EE; Quijano Cardé, NA1
Bui, BV; Burrows, EL; Churilov, L; Hannan, AJ; Lim, JKH; Nguyen, CTO; Shepherd, A; Wong, VHY; Zeleznikow-Johnston, AM1
Bohár, Z; Büki, A; Horvath, G; Kekesi, G; Vécsei, L1
Esmaeilpour, K; Joushi, S; Sheibani, V; Taherizadeh, Z1
Avelar, AJ; Cooper, SY; Henderson, BJ; Richardson, MR; Wright, SK; Wright, TD1
Holloman, FM; Hope, BT; Ramsey, LA; Shaham, Y; Venniro, M1
Caba, M; Daniel Caba-Flores, M; Huerta, C; Meza, E; Morales, T; Paredes, RG1
Majewski, M; Myers, KP; Schaefer, D; Tierney, A1
Ahn, S; Hahm, DH; Jang, JH; Jang, SY; Lee, Y; Park, HJ; Yeom, M1
Achim, C; Deben, D; Geyer, MA; Grant, IE; Kenton, JA; Milienne-Petiot, M; Minassian, A; Perry, W; Young, JW1
Baker, R; Cantor, M; Conlisk, D; de Guglielmo, G; George, O; Kallupi, M; Kimbrough, A; Simpson, S1
Hadjas, LC; Lüscher, C; Simmler, LD1
Alenina, N; Alonso, L; Peeva, P; Ramos-Prats, A; Rivalan, M; Winter, Y1
Awad, G; Befort, K; Massotte, D; Olmstead, MC; Roeckel, LA1
Nawarawong, NN; Olsen, CM1
Cottone, P; Leonard, MZ; Micovic, NM; Miczek, KA; Moore, CF; Sabino, V1
Hara, K; Kakuma, T; Kawahara, Y; Kojima, M; Mifune, H; Mitsuzono, R; Nishi, A; Nishi, Y; Sakai, Y; Sato, T; Tajiri, Y1
Ichitani, Y; Takahashi, K; Toyoshima, M; Yamada, K1
Chen, A; Hajós, M; Kelley, C; Leventhal, L; Martens, LH; Nagy, D; Stoiljkovic, M1
Andrews, AM; Cannella, LA; Corbett, CB; Kahn, J; McGary, H; Ramirez, SH; Razmpour, R1
Berta, B; Dusa, D; Gálosi, R; Kállai, V; Karádi, Z; Kertes, E; Kovács, A; László, K; Lénárd, L; Ollmann, T; Péczely, L; Tóth, A; Zagoracz, O1
Lane, AE; Lane, DA; Qian, L; Trubetckaia, O; Zhou, P1
Ahmed, OJ; Ahrens, AM1
Botha, TL; Brand, SJ; de Brouwer, G; Finger-Baier, K; van Staden, C; Wolmarans, D1
Dieterich, A; Floeder, J; Samuels, BA; Sharif, A; Srivastava, P; Stech, K; Yohn, SE1
Ng, KH; Sangha, S; Seibert, TA; Urbanczyk, PJ; Woon, EP1
Denys, D; Ehmer, I; Feenstra, M; Willuhn, I1
Correa, M; Presby, RE; Rotolo, RA; Salamone, JD; Yang, JH1
Cano, M; Gad, M; Green, KN; Leslie, FM; Linker, KE; Tawadrous, P; Wood, MA1
Nazarian, A; O'Dell, LE; Richardson, JR1
Braccagni, G; De Montis, MG; Gambarana, C; Scheggi, S1
Blanco-Gandía, MDC; Miñarro López, J; Ródenas-González, F; Rodriguez-Arias, M1
Ambrosio, E; Borcel, É; Higuera-Matas, A; Santos-Toscano, R; Ucha, M1
Eagle, DM; Milton, AL; Paulcan, S; Robbins, TW; Vousden, GH1
Cui, J; Song, L; Sun, B; Wang, N; Wang, R; Yan, J1
Radke, AK; Ramsey, OR; Sneddon, EA; Thomas, A1
An, T; Song, Z; Wang, JH1
Chakraborty, S; Raju, TR; Shankaranarayana Rao, BS; Tripathi, SJ1
Haghparast, A; Hesam, S; Karimi, S; Karimi-Haghighi, S; Razavi, Y1
Cope, ZA; Dulcis, D; Kwiatkowski, MA; Lavadia, ML; van de Cappelle, CJA; Young, JW1
Frankowska, M; Gamberini, S; Gawlińska, K; Gawliński, D; Jastrzębska, J; Pieniążek, R; Suder, A; Wydra, K1
Bermúdez, I; Cespedes, C; Esparza, E; Figueroa, C; González-Gutierrez, J; Hödar-Salazar, M; Iturriaga-Vásquez, P; Paillali, P; Quiroz, G; Reyes-Parada, M; Sotomayor-Zárate, R; Viscarra, F1
Fu, J; Ge, S; Lang, B; Li, J; Li, N; Li, Y; Qu, L; Volkow, ND; Wang, GJ; Wang, J; Wang, P; Wang, X; Wang, Y; Wu, H; Zeng, J; Zhang, Y1
Bell, RL; Hauser, SR; Katner, SN; McBride, WJ; Rodd, ZA; Truitt, WA; Waeiss, RA1
Barker, JM; Bryant, KG; Chandler, LJ; Goldwasser, B; Montiel-Ramos, A1
Chalhoub, RM; Kalivas, PW1
Chen, K; Huang, X; Huang, Y; Liu, J; Liu, X; Nie, B; Ren, P; Shen, X; Wu, L; Xu, M; Zhang, T; Zhou, J1
Fadda, P; Fattore, L; Fratta, W; Scherma, M1
Fadda, P; Fattore, L; Fratta, W; Zanda, MT1
Bryce, CA; Floresco, SB1
Banks, ML; Epstein, DH; Heilig, M; Shaham, Y; Venniro, M1
Furuie, H; Nakatake, Y; Ukezono, M; Yamada, M; Yoshizawa, K1
Baracz, SJ; Carey, HA; Cornish, JL; Everett, NA1
Carter, CW; Deisseroth, K; Delcasso, S; Diefenbach, TJ; DiMarco, KS; Drammis, SM; Friedman, A; Gibb, LG; Graybiel, AM; Hu, D; Hueske, E; Lutwak, H; Nelson, ED; Rakocevic, LI; Ramakrishnan, C; Rodriguez, RX; Siciliano, CA; Toro Arana, SE; Xiong, JK; Yoshida, T; Zhang, Q; Zhao, J1
Aleksandrova, LR; Burke, CJ; Euston, DR; Mauro, MH; Modlinska, K; Pellis, SM; Phillips, AG1
Haber, SN; Jezzini, A; Leuthardt, EC; Monosov, IE1
Galaj, E; Xi, ZX1
Barnes, SA; Brian, ML; Featherby, TJ; Hoyer, D; Jacobson, LH; Lawrence, AJ; Metha, JA; Murawski, C; Oberrauch, S1
Johansen, EB; López-Tolsa, GE; Pellón, R; Ramos, S; Sjoberg, EA1
Bilbao, A; Hertle, S; Spanagel, R; Wei, S1
Cirino, TJ; McLaughlin, JP1
Lopez, MJ; Pra Sisto, AJ; Vigorito, M1
Browning, KO; Nall, RW; Nist, AN; Shahan, TA; Sutton, GM1
Aguilar, MA; Calpe-López, C; De la Rubia Ortí, JE; García-Pardo, MP1
Cheng, CN; Chih Wei Huang, A; Chiu, WC; Lee, C; Wang, YC1
Adriani, W; Alleva, E; Curcio, G; Festucci, F; Oggiano, M; Parvopassu, A1
Haghparast, A; Katebi, SN; Riahi, E; Torkaman-Boutorabi, A; Vousooghi, N1
Ahmadi, S; Bradburn, S; Fotouhi, S; Khanizad, A; Masoudi, K; Mohammadi Talvar, S; Zobeiri, M1
Effendy, MA; Hassan, Z; Yunusa, S; Zain, ZM1
Islam, J; Kc, E; Kim, HK; Kim, S; Park, YS1
Adan, RAH; Boekhoudt, L; de Jong, JW; de Leeuw, AE; Luijendijk, MCM; Roelofs, TJM; van der Plasse, G; Wolterink-Donselaar, IG1
Aversa, D; Berretta, N; Cavallucci, V; Coccurello, R; Cordella, A; Cutuli, D; D'Amelio, M; De Bartolo, P; Dell'Acqua, MC; Federici, M; Giacovazzo, G; Keller, F; Krashia, P; Latagliata, EC; Marino, R; Mercuri, NB; Nobili, A; Petrosini, L; Puglisi-Allegra, S; Rizzo, FR; Sancandi, M; Viscomi, MT1
Cao, JL; Deisseroth, K; Ding, HL; Guo, XY; Han, MH; Koo, JW; Li, C; Liu, D; Liu, H; Liu, MJ; Mouzon, E; Nestler, EJ; Qian, YL; Wang, L; Wang, XY; Yang, JX; Zachariou, V; Zhang, H; Zhang, S1
Gajbhiye, SV; Petare, A; Potey, AV; Salve, B; Tripathi, RK1
Ide, S; Inoue, T; Minami, M; Minami, S; Satoyoshi, H; Yoshioka, M1
Aguilar, MA; Aracil-Fernández, A; Blanco-Gandía, MC; Ledesma, JC; Manzanares, J; Miñarro, J; Montagud-Romero, S; Navarrete, F; Rodríguez-Arias, M1
D'Aigle, J; Delville, Y; González-Martínez, LF; Lee, HJ; Lee, SM1
Foldi, CJ; Milton, LK; Oldfield, BJ1
Blanco, C; Hen, R; Nautiyal, KM; Okuda, M1
Aupperle, RL; Kirlic, N; Young, J1
Chang, YC; He, AB; Huang, ACW; Meng, AWY1
Laviolette, SR; Rosen, LG; Rushlow, WJ1
Acheson, SK; Darlow, M; Miller, KM; Risher, ML; Schramm-Sapyta, N; Sexton, HG; Swartzwelder, HS1
Ahmed, SH1
Accoto, A; Andolina, D; Coassin, A; D'Amato, FR; Di Segni, M; Lizzi, AR; Luchetti, A; Luzi, C; Pascucci, T; Ventura, R1
Fisher, DC; Fletcher, PJ; Li, Z; Zack, MH; Zeeb, FD1
Drozd, R; Rojek-Sito, K; Rygula, R1
Augsburger, M; Boutrel, B; Halfon, O; Jadhav, KS; Magistretti, PJ1
Beiser, T; Kohen, R; Numa, R; Yaka, R1
Brown, AR; Chomiak, T; Hu, B; Teskey, GC1
Bortolato, M; Fowler, SC; Hale, L; Hudnall, JL; Jarmolowicz, DP; Lemley, SM; Sofis, MJ1
Hellberg, SN; Levit, JD; Robinson, MJF1
Badve, PS; Barson, JR; Bass, CE; Bernstein, DL; España, RA1
Abel, T; Bowman, N; Commons, K; Grissom, NM; Havekes, R; Mahrt, E; McKee, SE; Nickl-Jockschat, T; O'Brien, WT; Portfors, C; Reyes, TM; Schoch, H; Siegel, S1
Aguilar, MA; Blanco-Gandía, MC; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M1
Brace, LR; Dommett, EJ; Gaeta, V; Rostron, CL1
Andrews, C; Bateson, M; Nettle, D; Neville, V1
Fortress, AM; Pang, KCH; Spiegler, KM1
Amitai, N; Powell, SB; Young, JW1
Hutchinson, CV; Mohammed Jawad, RA; Prados, J1
Belin, D; Everitt, BJ; Giuliano, C1
Amano, T; Asaoka, Y; Ide, S; Kato, T; Minami, M1
Cui, Y; Dong, Y; Hu, H; Ma, S; Ni, Z; Sang, K; Yang, Y1
Cope, ZA; Dulcis, D; Romoli, B; Schrurs, E; Sharp, RF; van Enkhuizen, J; Young, JW1
Bates, V; Bilkey, DK; Maharjan, A; Millar, J; Ward, RD1
Christian, DL; Dantzer, R; Estrada, DJ; Grossberg, AJ; Heijnen, CJ; Kavelaars, A; Laumet, G; Vichaya, EG1
Hamed, A; Kursa, MB1
Andreatini, R; Braun, MD; Kisko, TM; Schwarting, RKW; Vecchia, DD; Wöhr, M1
Balázsa, T; Durst, M; Eyre, MD; Könczöl, K; Tóth, ZE1
Bailey, A; Camarini, R; Chivers, P; Georgiou, P; Rae, M; Zanos, P1
Ballard, I; Diehl, MM; Lempert, KM; Parr, AC; Smith, DV; Steele, VR1
Hildebrandt, BA; Klump, KL; Sinclair, EB; Sisk, CL1
Callan, G; Choi, S; Hurley, MM; Robble, MR; Wheeler, RA1
Duan, Y; Li, M; Li, Y; Liang, J; Meng, X; Qi, K; Shen, F; Sui, N1
Becker, JAJ; Clément, C; Le Merrer, J; Pellissier, LP; Pujol, CN1
Ivanova, SA; Loonen, AJ1
Bossert, JM; Fredriksson, I; Lofaro, OM; Reiner, DJ; Shaham, Y1
Bussey, TJ; Lopez-Cruz, L; Phillips, BU; Saksida, LM1
Blasio, A; Cottone, P; Moore, CF; Sabino, V1
Bi, GH; Gardner, E; Iyer, MR; Martinez, MJ; Paik, P; Rice, KC; Sulima, A; Uhl, GR; Xi, ZX1
Allain, F; Gueye, AB; Samaha, AN1
Gardner, EL; Wang, B; Wise, RA; You, ZB1
Ballestín, R; Castro-Zavala, A; Ferrer-Pérez, C; Filarowska, J; Luján, MÁ; Miñarro, J; Rodríguez-Arias, M; Valverde, O1
Haghparast, A; Karimi, S; Razavi, Y; Riahi, E; Zarrabian, S1
Alexander, L; Clarke, HF; Cockcroft, GJ; Fryer, TD; Gaskin, PLR; Hong, YT; Roberts, AC; Sawiak, SJ1
Fukuhara, S; Hosoi, H; Kodo, K; Kosaka, K; Mori, J; Morimoto, H; Morimoto, M; Moroto, M; Nakajima, H; Shigehara, K; Sugimoto, S; Tsuma, Y1
Aylward, J; Hales, C; Robinson, E; Robinson, OJ1
Chen, E; Eugene, AJ; Fowler, CD; Fowler, JP; Lallai, V; Pushkin, AN; Torres-Mendoza, A1
Cachope, R; Carson, BP; Cheer, JF; Cole, EA; Fitoussi, A; Gildish, I; Sesia, T; Zlebnik, NE1
Andersen, JM; Bogen, IL; Boix, F; Kvello, AMS; Mørland, J1
Barron, C; Bashir, A; Cheng, WH; Cheung, H; Cripton, PA; Ladner, T; Martens, KM; McInnes, KA; Stukas, S; Vonder Haar, C; Welch, KA; Wellington, CL; Winstanley, CA1
Golden, SA; Jin, M; Shaham, Y1
Garcia, BJ; Glass, JD; Jacobson, DA; Jones, PC; Prosser, RA; Yaw, AM1
Hernandez, NS; Schmidt, HD1
Alcaraz-Iborra, M; Cubero, I; de la Fuente, L; Rodríguez-Ortega, E1
Duan, Y; Jiang, FZ; Jin, SB; Li, M; Liang, J; Shen, F; Sui, N; Zhang, JJ; Zheng, W1
Fox, ME; Lobo, MK1
Crocker, AJ; Engel, GL; Taber, K; Vinton, E1
Christensen, DR; Dorchak, DL; Euston, DR; Laskowski, CS; Ward, KM1
Chen, JG; Gao, SQ; He, JG; Hu, ZL; Shen, ZC; Wang, F; Xu, JF; Zhang, H; Zhang, PW; Zhao, HH; Zheng, HL1
Carr, ZJ; Karamchandani, K; Kunselman, AR; Miller, L; Ruiz-Velasco, V1
Dawe, GS; Marwari, S1
Fry, BR; Gifford, R; Johnson, AW; Manning, CE; Niwa, M; Robles, CF; Russell, N; Sawa, A1
Clark, JD; Nwaneshiudu, CA; Shi, XY1
Akil, H; Blandino, P; Goldman, D; Hodgkinson, CA; Shen, PH; Virkkunen, M; Watson, SJ; Yuan, Q; Zhou, Z1
Basiri, ML; Breen, G; Bryois, J; Bulik, CM; Guo, W; Hübel, C; Kosyk, O; McHenry, JA; Otis, JM; Rossi, MA; Stuber, GD; Sullivan, PF; van den Munkhof, HE1
Benn, A; Dwyer, DM; Lewis, LR; Robinson, ESJ1
Andrews, AM; Cannella, LA; Collie, C; Kaufman, MJ; Maynard, M; McGary, H; Ramirez, SH; Rawls, SM; Razmpour, R; Tran, F; Tsegaye, T1
Aparicio, MB; Engelmann, AJ; Grant, Y; Kim, A; Mandyam, CD; Sobieraj, JC; Yuan, CJ1
Atkinson, NS; Robinson, BG1
Huston, JP; Komorowski, M; Schulz, D; Silva, MA; Topic, B1
Ahmed, SH; Baekelandt, V; Bezard, E; Cador, M; Engeln, M; Fasano, S; Fernagut, PO1
Butler, P; Munafò, MR; Nutt, DJ; Robinson, ES; Stuart, SA1
Ducat, E; Kreek, MJ; Picetti, R; Ray, B; Schlussman, SD; Yuferov, V; Zhou, Y1
Brown, VJ; Dunnett, SB; Lindgren, HS; Tait, DS; Wickens, R1
Cahill, CM; Grenier, P; Lecour, S; Magnussen, C; Olmstead, MC; Xue, L1
Devineni, AV; Heberlein, U1
Chen, L; Chen, S; He, Y; Li, S; Li, Y; Liu, X; Shi, Z; Sun, L; Sun, X; Zeng, J1
Cui, C; Hu, L; Li, Y; Sun, L1
Akil, H; Aldridge, JW; Flagel, SB; Garcia-Fuster, MJ; Perez-Sepulveda, JA; Slusky, RJ; Watson, S1
Barbier, E; Chen, X; Damaj, MI; Jackson, KJ; Wang, JB1
Collier, AD; Echevarria, DJ1
Ahmed, SH; Augier, E; Lenoir, M; Vouillac, C1
Aihara, M; Inagaki, M1
Arnold, R; Gjeloshi, V; Kalueff, AV; Kondaveeti, D; Mikhaylova, A; Neelkantan, N; Poudel, MK; Stewart, AM1
Boraud, T; Dejean, C; Fourneaux, B; Leinekugel, X; Retailleau, A1
Bamba, T; Bando, K; Fukusaki, E; Horie, H; Ishii, A; Katagi, M; Miyawaki, I; Sato, T; Shima, N; Suzuki, K; Tatsuno, M; Tsuchihashi, H; Zaitsu, K1
D'Souza, MS; Der-Avakian, A; Markou, A; Pizzagalli, DA1
Nylander, I; Roman, E1
Forster, GL; Miiller, LC; Novick, AM; Watt, MJ1
Barnes, SA; Der-Avakian, A; Markou, A1
Drgonova, J; Hall, FS; Uhl, GR1
Diberto, JF; Fish, EW; Krouse, MC; Malanga, CJ; Robinson, JE; Stringfield, SJ1
Bannerman, D; Dix, SL; Garner, JP; Gaskill, BN; Gilmour, G; Pioli, EY; Tricklebank, MD1
Jauch-Chara, K; Oltmanns, KM1
Martin-Fardon, R; Weiss, F2
Cepeda, C; Cui, Y; Evans, CJ; Ge, W; James, AS; Jentsch, JD; Kieffer, BL; Levine, MS; Maidment, NT; Mittal, N; Murphy, NP; Ostlund, SB; Park, CS; Roberts, KW; Sun, YE; Walwyn, WM; Yang, XW1
Lagorio, CH; Winger, G1
Aston-Jones, G; Beckley, JT; Deisseroth, K; Kaufling, J; Keistler, CR; Mahler, SV; McGlinchey, EM; Vazey, EM; Wilson, SP; Woodward, JJ1
Białko, M; Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E1
Brabant, C; Guarnieri, DJ; Quertemont, E1
Cocker, PJ; Hosking, JG; Rogers, RD; Tremblay, M; Winstanley, CA; Zeeb, FD1
Hou, YY; Lu, YG; Pan, ZZ; Tao, W; Wang, W; Zhang, Z1
Brennan, KA; Crowther, A; Putt, F; Roper, V; Truman, P; Waterhouse, U1
Dwoskin, LP; Gauthier, JM; Kantak, KM; Tassin, DH1
Bagdas, D; Damaj, MI; Muldoon, PP; Tyndale, RF; Zhu, AZ1
Caramillo, EM; Collier, AD; Echevarria, DJ; Khan, KM; Mohn, RS1
Dantzer, R; Hunt, SC; Vichaya, EG1
Drucker-Colín, R; Valle-Leija, P1
Blood, A; Breiter, HC; Chen, LL; Chou, CW; Kim, H; Lim, G; Mao, J; Marota, JJ; McCabe, MF; Wang, S1
Kanazawa, M; Kubota, H; Mori, T; Rahmadi, M; Shibasaki, M; Suzuki, T1
Bouchard, C; Ducrot, C; Fortier, E; Gallo, A; Rompré, PP1
Aldavert-Vera, L; Huguet, G; Kádár, E; Morgado-Bernal, I; Ramoneda, M; Segura-Torres, P1
Han, J; Sui, N; Zhang, JJ1
Arndt, SS; Szczodry, O; van der Staay, FJ1
Brown, RM; Chen, A; Chen, NA; Jupp, B; Kim, JH; Lawrence, AJ; Lebow, M; Sztainberg, Y1
Bialy, M; Boguszewski, PM; Nikolaev, E; Nikolaev-Diak, A; Socha, A; Strefnel, M1
Aguiar, DC; Almeida-Santos, AF; Duarte, ID; Ferreira, RC; Gobira, PH; Moreira, FA; Romero, TR; Souza, DP1
Guo, Y; Jin, L; Nie, Z; Pan, L; Zheng, Y; Zhu, R1
Kaniuga, E; Lehner, MH; Płaźnik, A; Skórzewska, A; Sobolewska, A; Taracha, E; Turzyńska, D; Wisłowska-Stanek, A; Wróbel, J1
Donaire, R; Manzo, L; Papini, MR; Sabariego, M; Torres, C1
Grenald, SA; Largent-Milnes, TM; Vanderah, TW1
Gregg, M; Martin, L; Sample, H; Wood, C1
Amaral, AC; Galler, JR; McGaughy, JA; Mokler, DJ; Morgane, PJ; Rosene, DL; Rushmore, RJ1
Caprioli, D; Li, X; Marchant, NJ1
Cocker, PJ; Winstanley, CA1
Braithwaite, VA; Caruso, MJ; Cavigelli, SA; Chaby, LE; Hirrlinger, AM1
Alexander, DN; Anosike, N; Ballard, SM; Carter, AB; Cox, TA; Freet, CS; Grigson, PS; Imperio, CG; Mahmoud, S; Ruiz-Velasco, V1
Li, X; Wolf, ME1
Broekhoven, MH; Damsteegt, R; Limpens, JH; Vanderschuren, LJ; Voorn, P1
Belzung, C; Castelnau, P; Chalon, S; Cortese, S; Emond, P; Faraone, SV; Galineau, L; Lepelletier, FX; Nicolas, C; Solinas, M; Tauber, C1
Caprioli, D; Thorndike, EB; Venniro, M; Zeric, T1
Clementz, MA; Jablonski, J; McLaughlin, JP; Mediouni, S; Paris, JJ; Thenin-Houssier, S; Valente, ST1
Albelda, NS; Goltseker, K; Joel, D; Yankelevitch-Yahav, R1
Becker, A; Grecksch, G1
Cruz, FC; de Guglielmo, G; George, O; Hope, BT; Koob, GF; Leão, RM; Logrip, ML; Planeta, CS; Vendruscolo, LF1
Chefer, VI; Chen, M; DiBerto, JF; Fish, EW; Gigante, E; Heilig, M; Krouse, MC; Malanga, CJ; Robinson, JE; Roth, BL; Sun, H; Thorsell, A; Vardy, E; White, KL1
Grater, DM; Morgan, C; Shannonhouse, JL; Wellman, PJ; York, D1
Burton, AC; Hernandez, A; O'Donnell, P; Roesch, MR; Schoenbaum, G1
Carlson, CR; Danaher, RJ; Kniffin, TC; Ma, F; Miller, CS; Westlund, KN1
Budde, MD; Lim, YW; Meyer, NP; Olsen, CM; Shah, AS; Stemper, BD1
Balsam, PD; Higa, KK; Kahn, JB; Kandel, ER; Simpson, EH; Ward, RD; Winiger, V1
Borkar, CD; Kokare, DM; Shelkar, GP; Subhedar, NK; Upadhya, MA1
Carito, V; Ceccanti, M; Chaldakov, GN; Ciafrè, S; Coccurello, R; Codazzo, C; Ferraguti, G; Fiore, M; Giacovazzo, G; Mancinelli, R; Pascale, E; Tirassa, P1
Jaisinghani, S; Rosenkranz, JA1
Howe, WM; Kozak, R; Oomen, C; Tierney, PL; Young, DA1
Clark, JJ; Lesscher, HM; Spoelder, M; Tsutsui, KT; Vanderschuren, LJ1
Corbit, LH; Leung, HT1
Bharne, AP; Borkar, CD; Kokare, DM; Subhedar, NK1
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Cahill, CM; Castonguay, A; Cook, C; De Koninck, Y; Evans, CJ; Ghogha, A; Murphy, NP; Olmstead, MC; Taylor, AJ; Taylor, AM; Xue, L1
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Cuadra, GR; de Olmos, JS; de Olmos, S; Orsingher, OA; Valdomero, A; Velazquez, EE1
Bassel-Duby, R; Covington, HE; Graham, A; Haggarty, SJ; Kerstetter, KA; Kippin, TE; Krishnan, V; Kumar, A; Maze, I; McKinsey, TA; Nestler, EJ; Neve, RL; Olson, EN; Renthal, W; Russo, SJ; Tsankova, N; Xiao, G1
Hnasko, TS; Palmiter, RD; Sotak, BN1
Bossert, JM; Koya, E; Poles, GC; Shaham, Y; Wihbey, KA1
Lin, Y; Quartermain, D; Stone, EA1
Alvarez-Jaimes, L; Parsons, LH; Polis, I1
Akhavan, A; Festa, ED; Jenab, S; Luine, V; Minerly, AC; Nazarian, A; Niyomchai, T; Quiñones-Jenab, V; Russo, SJ; Sun, WL; Weierstall, K1
Dremencov, E; Friedman, A; Friedman, Y; Yadid, G1
Mizoguchi, H; Nabeshima, T; Yamada, K1
Parelkar, NK; Wang, JQ1
Fratta, W; González-Cuevas, G; López-Moreno, JA; Navarro, M; Rodríguez de Fonseca, F; Scherma, M1
Akbarian, S; Jones, SR; Konradi, C; Matevossian, A; Penta, KL; Schroeder, FA; Tapper, AR1
Kobayashi, Y; Kurahashi, K; Nakamura, A; Narita, M; Niikura, K; Okutsu, D; Ozeki, A; Suzuki, M; Suzuki, T1
Moscovitch, M; Rosenbaum, RS; Sekeres, M; Winocur, G1
Abumaria, N; Flügge, G; Fuchs, E; Havemann-Reinecke, U; Hiemke, C; Rüther, E; Rygula, R; Zernig, G1
Glick, SD; Meibach, RC; Weaver, LM1
Heinrichs, S; Koob, GF; Rassnick, S; Weiss, F1
Belknap, JK; Buck, KJ; Crabbe, JC1
Forbes, NF; Matthews, K; Reid, IC; Stewart, CA1
Stolerman, I2
Epping-Jordan, MP; Koob, GF; Markou, A; Watkins, SS1
Agmo, A; Huston, JP; Schildein, S; Schwarting, RK1
Gurmankin, C; Rudski, J1
Bloom, FE; Koob, GF; Sanna, PP1
Kosofsky, BE; Malanga, CJ1
Grimm, JW; See, RE1
Le Foll, B; Schwartz, JC; Sokoloff, P1
Paré, WP1
De Montis, MG; Gambarana, C; Scheggi, S; Tagliamonte, A; Tolu, P1
Cardinal, RN; Everitt, BJ; Pennicott, DR; Robbins, TW; Sugathapala, CL1
Harrison, AA; Liem, YT; Markou, A1
Crothers, MK; Garcia, SA; Giordano, T; Goyarzu, P; Kowall, NW; Lake, JR; Malin, DH; Plotner, RE; Spell, SH; Tomsic, BJ1
Markou, A; Paterson, NE1
Casu, MA; Colombo, G; Gessa, GL; Pani, L1
Bozarth, MA; Pudiak, CM1
Hirsh, J1
Maldonado, R; Rodríguez de Fonseca, F1
Ahmed, SH; Kenny, PJ; Koob, GF; Markou, A1
Gaudet, L; Le Pen, G; Moreau, JL; Mortas, P; Mory, R1
Binks, SM; Greenwood, DT; Murchie, JK1
Iversen, SD; Tye, NC1
Ramsey, NF; Van Ree, JM1
Muscat, R; Papp, M; Willner, P1
Chen, KS; Squire, LR; Zola-Morgan, S1
Chase, MH; Wyrwicka, W1
Gazzaniga, MS1
Aakre, B; Geist, CR; Strobel, DA; Zimmermann, RR1
Martin, GE; Myers, RD1
Chamove, AS; Davenport, JW1

Reviews

96 review(s) available for s,n,n'-tripropylthiocarbamate and Disease Models, Animal

ArticleYear
Neural circuits linking sleep and addiction: Animal models to understand why select individuals are more vulnerable to substance use disorders after sleep deprivation.
    Neuroscience and biobehavioral reviews, 2020, Volume: 108

    Topics: Animals; Behavior, Addictive; Brain; Disease Models, Animal; Disease Susceptibility; Humans; Individuality; Motivation; Reward; Sleep Deprivation; Substance-Related Disorders

2020
Non-Opioid Treatments for Opioid Use Disorder: Rationales and Data to Date.
    Drugs, 2020, Volume: 80, Issue:15

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Brain; Buprenorphine; Disease Models, Animal; Endocannabinoids; Glutamic Acid; Humans; Methadone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Orexins; Reward; Secondary Prevention; Signal Transduction; Treatment Outcome

2020
Improving translation of animal models of addiction and relapse by reverse translation.
    Nature reviews. Neuroscience, 2020, Volume: 21, Issue:11

    Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Drug-Seeking Behavior; Recurrence; Reinforcement, Psychology; Reward; Substance-Related Disorders; Translational Research, Biomedical

2020
Anterior Cingulate Cortex and the Control of Dynamic Behavior in Primates.
    Current biology : CB, 2020, 12-07, Volume: 30, Issue:23

    Topics: Animals; Behavior, Animal; Central Nervous System Diseases; Choice Behavior; Cortical Excitability; Disease Models, Animal; Drug Evaluation, Preclinical; Frontal Lobe; Gyrus Cinguli; Humans; Information Seeking Behavior; Learning; Macaca mulatta; Neurons; Reward; Uncertainty

2020
Possible Receptor Mechanisms Underlying Cannabidiol Effects on Addictive-like Behaviors in Experimental Animals.
    International journal of molecular sciences, 2020, Dec-24, Volume: 22, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cannabidiol; Cannabinoids; Disease Models, Animal; Dopamine; Humans; Methamphetamine; Piperidines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptor, Serotonin, 5-HT1A; Recurrence; Reward; Self Administration; Substance-Related Disorders; TRPV Cation Channels

2020
Mini review: Promotion of substance abuse in HIV patients: Biological mediation by HIV-1 Tat protein.
    Neuroscience letters, 2021, 05-14, Volume: 753

    Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Disease Models, Animal; Ethanol; HIV Infections; HIV-1; Humans; Mice; Quality of Life; Reward; Substance-Related Disorders; tat Gene Products, Human Immunodeficiency Virus

2021
A focus on reward in anorexia nervosa through the lens of the activity-based anorexia rodent model.
    Journal of neuroendocrinology, 2017, Volume: 29, Issue:10

    Topics: Animals; Anorexia Nervosa; Brain; Disease Models, Animal; Dopamine; Humans; Mice; Neurosecretory Systems; Rats; Reward; Serotonin

2017
Gambling disorder: an integrative review of animal and human studies.
    Annals of the New York Academy of Sciences, 2017, Volume: 1394, Issue:1

    Topics: Animals; Combined Modality Therapy; Comorbidity; Disease Models, Animal; Gambling; Genetic Predisposition to Disease; Humans; Prognosis; Punishment; Reward; Risk Factors

2017
Animal to human translational paradigms relevant for approach avoidance conflict decision making.
    Behaviour research and therapy, 2017, Volume: 96

    Topics: Animals; Anxiety Disorders; Avoidance Learning; Conflict, Psychological; Decision Making; Disease Models, Animal; Forecasting; Humans; Reward; Translational Research, Biomedical

2017
Individual decision-making in the causal pathway to addiction: contributions and limitations of rodent models.
    Pharmacology, biochemistry, and behavior, 2018, Volume: 164

    Topics: Animals; Causality; Decision Making; Disease Models, Animal; Humans; Impulsive Behavior; Reward; Rodentia; Substance-Related Disorders

2018
Addictive behaviour in experimental animals: prospects for translation.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018, 03-19, Volume: 373, Issue:1742

    Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Humans; Memory; Mice; Pharmaceutical Preparations; Primates; Rats; Reinforcement, Psychology; Reward; Translational Research, Biomedical

2018
The evolutionary old forebrain as site of action to develop new psychotropic drugs.
    Journal of psychopharmacology (Oxford, England), 2018, Volume: 32, Issue:12

    Topics: Animals; Anura; Avoidance Learning; Disease Models, Animal; Dopamine; Drug Development; Humans; Lampreys; Mental Disorders; Prosencephalon; Psychotropic Drugs; Reward

2018
Relapse to opioid seeking in rat models: behavior, pharmacology and circuits.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:3

    Topics: Animals; Brain; Craving; Disease Models, Animal; Extinction, Psychological; Opioid-Related Disorders; Rats; Recurrence; Reward; Substance Withdrawal Syndrome

2019
Translational tests involving non-reward: methodological considerations.
    Psychopharmacology, 2019, Volume: 236, Issue:1

    Topics: Animals; Association Learning; Brain; Conditioning, Classical; Conditioning, Operant; Delay Discounting; Disease Models, Animal; Dopamine; Humans; Male; Motivation; Neurotransmitter Agents; Reinforcement, Psychology; Reversal Learning; Reward; Schizophrenia; Schizophrenic Psychology; Serotonin; Translational Research, Biomedical

2019
The potential role of the orexin reward system in future treatments for opioid drug abuse.
    Brain research, 2020, 03-15, Volume: 1731

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Disease Models, Animal; Drug-Seeking Behavior; Humans; Hypothalamic Area, Lateral; Morphine; Neural Pathways; Opioid-Related Disorders; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Reward

2020
Animal Models of (or for) Aggression Reward, Addiction, and Relapse: Behavior and Circuits.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019, 05-22, Volume: 39, Issue:21

    Topics: Aggression; Animals; Behavior, Addictive; Disease Models, Animal; Mice; Recurrence; Reward

2019
Central GLP-1 receptors: Novel molecular targets for cocaine use disorder.
    Physiology & behavior, 2019, 07-01, Volume: 206

    Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Humans; Reward; Self Administration

2019
The molecular and cellular mechanisms of depression: a focus on reward circuitry.
    Molecular psychiatry, 2019, Volume: 24, Issue:12

    Topics: Anhedonia; Animals; Depression; Depressive Disorder, Major; Disease Models, Animal; Humans; Motivation; Reward; Social Behavior; Weight Loss

2019
Studying alcohol use disorder using Drosophila melanogaster in the era of 'Big Data'.
    Behavioral and brain functions : BBF, 2019, Apr-16, Volume: 15, Issue:1

    Topics: Alcoholism; Animals; Behavior, Animal; Big Data; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Ethanol; Learning; Memory; Reward

2019
Affective biases and their interaction with other reward-related deficits in rodent models of psychiatric disorders.
    Behavioural brain research, 2019, 10-17, Volume: 372

    Topics: Affective Symptoms; Animals; Bias; Cognition; Depressive Disorder, Major; Disease Models, Animal; Emotions; Humans; Learning; Memory; Mental Disorders; Mice; Quality of Life; Rats; Reward

2019
Animal models of extinction-induced depression: loss of reward and its consequences.
    Neuroscience and biobehavioral reviews, 2013, Volume: 37, Issue:9 Pt A

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Extinction, Psychological; Humans; Reinforcement, Psychology; Reward

2013
Addictions and stress: clues for cocaine pharmacotherapies.
    Current pharmaceutical design, 2013, Volume: 19, Issue:40

    Topics: Animals; Behavior, Addictive; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Reward; Sex Factors; Signal Transduction; Stress, Physiological; Substance-Related Disorders

2013
The evolution of Drosophila melanogaster as a model for alcohol research.
    Annual review of neuroscience, 2013, Jul-08, Volume: 36

    Topics: Alcoholism; Animals; Biological Evolution; Disease Models, Animal; Drosophila melanogaster; Ethanol; Humans; Reward; Self Administration

2013
The utility of the zebrafish model in conditioned place preference to assess the rewarding effects of drugs.
    Behavioural pharmacology, 2013, Volume: 24, Issue:5-6

    Topics: Animals; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Motivation; Reward; Self Administration; Substance-Related Disorders; Zebrafish

2013
[Neuroscience of attention deficit/hyperactivity disorder: special focus on the function of the inhibitory and reward systems].
    No to hattatsu = Brain and development, 2010, Volume: 42, Issue:3

    Topics: Animals; Attention; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Humans; Neurosciences; Reward

2010
Perspectives on zebrafish models of hallucinogenic drugs and related psychotropic compounds.
    ACS chemical neuroscience, 2013, Aug-21, Volume: 4, Issue:8

    Topics: Animals; Anxiety; Behavior, Animal; Biomarkers; Biomedical Research; Cognition; Disease Models, Animal; Drug Evaluation, Preclinical; Hallucinogens; Motor Activity; Phenotype; Psychopharmacology; Psychotropic Drugs; Reward; Social Behavior; Zebrafish

2013
Is the rodent maternal separation model a valid and effective model for studies on the early-life impact on ethanol consumption?
    Psychopharmacology, 2013, Volume: 229, Issue:4

    Topics: Age Factors; Alcohol Drinking; Animals; Animals, Newborn; Disease Models, Animal; Ethanol; Female; Humans; Male; Maternal Deprivation; Mice; Rats; Reward; Stress, Psychological

2013
Anhedonia, avolition, and anticipatory deficits: assessments in animals with relevance to the negative symptoms of schizophrenia.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:5

    Topics: Anhedonia; Animals; Anticipation, Psychological; Disease Models, Animal; Humans; Motivation; Neuropsychological Tests; Reward; Schizophrenia; Schizophrenic Psychology

2014
Curious cases: Altered dose-response relationships in addiction genetics.
    Pharmacology & therapeutics, 2014, Volume: 141, Issue:3

    Topics: Animals; Behavior, Addictive; Disease Models, Animal; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Mice; Phenotype; Polymorphism, Single Nucleotide; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders

2014
Obesity--a neuropsychological disease? Systematic review and neuropsychological model.
    Progress in neurobiology, 2014, Volume: 114

    Topics: Animals; Brain; Cognition Disorders; Disease Models, Animal; Eating; Humans; Obesity; Reward

2014
Stimulant and motivational effects of alcohol: lessons from rodent and primate models.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 122

    Topics: Alcohol Drinking; Alcoholism; Animals; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Humans; Motivation; Primates; Reward; Species Specificity

2014
Animal models for opioid addiction drug discovery.
    Expert opinion on drug discovery, 2014, Volume: 9, Issue:11

    Topics: Animals; Disease Models, Animal; Drug Discovery; Drug Tolerance; Humans; Opioid-Related Disorders; Recurrence; Reward; Substance Withdrawal Syndrome

2014
Recent updates on incubation of drug craving: a mini-review.
    Addiction biology, 2015, Volume: 20, Issue:5

    Topics: Animals; Behavior, Addictive; Brain; Craving; Cues; Disease Models, Animal; Dopamine; Drug-Seeking Behavior; Glutamic Acid; Humans; Recurrence; Reward; Substance-Related Disorders

2015
Irrational beliefs, biases and gambling: exploring the role of animal models in elucidating vulnerabilities for the development of pathological gambling.
    Behavioural brain research, 2015, Feb-15, Volume: 279

    Topics: Animals; Conditioning, Operant; Corpus Striatum; Decision Making; Disease Models, Animal; Gambling; Gyrus Cinguli; Humans; Rats; Receptors, Dopamine D2; Receptors, Dopamine D4; Reward; Risk

2015
Multiple faces of BDNF in cocaine addiction.
    Behavioural brain research, 2015, Feb-15, Volume: 279

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corpus Striatum; Craving; Disease Models, Animal; Mice; Neuronal Plasticity; Rats; Receptors, AMPA; Reward; Self Administration

2015
[Depression and addiction comorbidity: towards a common molecular target?].
    Medecine sciences : M/S, 2015, Volume: 31, Issue:5

    Topics: Anhedonia; Animals; Annexin A2; Appetitive Behavior; Cholinergic Neurons; Cocaine; Comorbidity; Depression; Depressive Disorder; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Humans; Interneurons; Mice; Mice, Knockout; Molecular Targeted Therapy; Nerve Tissue Proteins; Neural Pathways; Neurotransmitter Agents; Nucleus Accumbens; Optogenetics; Pleasure; Prevalence; Protein Transport; Receptors, Neurotransmitter; Reward; RNA Interference; S100 Proteins; Substance-Related Disorders

2015
The Two Faces of Social Interaction Reward in Animal Models of Drug Dependence.
    Neurochemical research, 2016, Volume: 41, Issue:3

    Topics: Animals; Cocaine-Related Disorders; Disease Models, Animal; Mice; Rats; Reward; Social Behavior; Substance-Related Disorders

2016
Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia.
    Schizophrenia bulletin, 2015, Volume: 41, Issue:5

    Topics: Animals; Conditioning, Operant; Disease Models, Animal; Humans; Motivation; Neuropsychological Tests; Reward; Rodentia; Schizophrenia; Translational Research, Biomedical

2015
Role of the Brain's Reward Circuitry in Depression: Transcriptional Mechanisms.
    International review of neurobiology, 2015, Volume: 124

    Topics: Animals; Brain; Depression; Disease Models, Animal; Gene Expression Regulation; Humans; Neural Pathways; Reward; Transcription Factors

2015
Skewed by Cues? The Motivational Role of Audiovisual Stimuli in Modelling Substance Use and Gambling Disorders.
    Current topics in behavioral neurosciences, 2016, Volume: 27

    Topics: Acoustic Stimulation; Animals; Attention; Choice Behavior; Conditioning, Classical; Cues; Disease Models, Animal; Gambling; Humans; Motivation; Photic Stimulation; Reward; Rodentia; Substance-Related Disorders

2016
The long pursued Holy Grail of the true "alcoholic" rat.
    Brain research, 2016, 08-15, Volume: 1645

    Topics: Alcohol Drinking; Alcohol-Related Disorders; Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Ethanol; Rats; Reward; Ventral Tegmental Area

2016
The pharmacology of effort-related choice behavior: Dopamine, depression, and individual differences.
    Behavioural processes, 2016, Volume: 127

    Topics: Animals; Choice Behavior; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine; Dopamine Antagonists; Humans; Individuality; Nucleus Accumbens; Reinforcement Schedule; Reward

2016
Common Neurogenetic Diagnosis and Meso-Limbic Manipulation of Hypodopaminergic Function in Reward Deficiency Syndrome (RDS): Changing the Recovery Landscape.
    Current neuropharmacology, 2017, Volume: 15, Issue:1

    Topics: Animals; Behavior, Addictive; Disease Models, Animal; Dopamine; Dopamine Agonists; Genetic Predisposition to Disease; Humans; Limbic System; Reward

2017
Neural changes induced by antipsychotic administration in adolescence: A review of studies in laboratory rodents.
    Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:8

    Topics: Adolescent; Adolescent Development; Animals; Antipsychotic Agents; Brain; Disease Models, Animal; Humans; Neural Pathways; Reward; Rodentia; Time Factors

2016
Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials.
    Depression and anxiety, 2016, Volume: 33, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Brain; CREB-Binding Protein; Disease Models, Animal; Dynorphins; Gene Expression Regulation; Humans; Narcotic Antagonists; Nucleus Accumbens; Receptors, Opioid, kappa; Reward; Stress, Psychological; Substance-Related Disorders; Translational Research, Biomedical

2016
Irritability in Youths: A Translational Model.
    The American journal of psychiatry, 2017, 06-01, Volume: 174, Issue:6

    Topics: Adolescent; Amygdala; Anger; Animals; Anxiety; Attention Deficit and Disruptive Behavior Disorders; Child; Child Behavior Disorders; Disease Models, Animal; Fear; Frustration; Humans; Irritable Mood; Longitudinal Studies; Mood Disorders; Prefrontal Cortex; Prognosis; Reward; Translational Research, Biomedical

2017
Modelling depression in animals: at the interface of reward and stress pathways.
    Psychopharmacology, 2017, Volume: 234, Issue:9-10

    Topics: Animals; Brain; Depressive Disorder, Major; Disease Models, Animal; Humans; Neural Pathways; Reward; Self Stimulation; Stress, Psychological; Substance Withdrawal Syndrome

2017
Chronic social stress, hedonism and vulnerability to obesity: lessons from rodents.
    Neuroscience and biobehavioral reviews, 2009, Volume: 33, Issue:4

    Topics: Animals; Body Weight; Disease Models, Animal; Eating; Energy Metabolism; Humans; Obesity; Reward; Social Environment; Stress, Psychological

2009
Insulin, leptin, and food reward: update 2008.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:1

    Topics: Adiposity; Animals; Disease Models, Animal; Dopamine; Eating; Feeding Behavior; Food Preferences; Homeostasis; Humans; Insulin; Leptin; Mesencephalon; Motivation; Neural Pathways; Obesity; Opioid Peptides; Reward; Signal Transduction

2009
Rodent models of nicotine reward: what do they tell us about tobacco abuse in humans?
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:4

    Topics: Animals; Disease Models, Animal; Humans; Mice; Nicotine; Nicotinic Agonists; Rats; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder

2009
Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties.
    Current drug abuse reviews, 2008, Volume: 1, Issue:3

    Topics: Animals; Arachidonic Acids; Brain; Cannabinoids; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Drug Tolerance; Endocannabinoids; Humans; Macaca mulatta; Marijuana Abuse; Mice; Motivation; Polyunsaturated Alkamides; Rats; Receptor, Cannabinoid, CB1; Reward; Self Administration; Substance Withdrawal Syndrome; Synaptic Transmission

2008
Role of BDNF and GDNF in drug reward and relapse: a review.
    Neuroscience and biobehavioral reviews, 2010, Volume: 35, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Choice Behavior; Disease Models, Animal; Extinction, Psychological; Glial Cell Line-Derived Neurotrophic Factor; Humans; Illicit Drugs; Recurrence; Reward; Self Administration; Substance-Related Disorders

2010
Current perspectives on selective dopamine D(3) receptor antagonists as pharmacotherapeutics for addictions and related disorders.
    Annals of the New York Academy of Sciences, 2010, Volume: 1187

    Topics: Alcoholism; Animals; Brain; Conditioning, Psychological; Disease Models, Animal; Dopamine Antagonists; Drug Design; Humans; Mice; Models, Neurological; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Substance-Related Disorders

2010
Adolescence as a critical window for developing an alcohol use disorder: current findings in neuroscience.
    Current opinion in psychiatry, 2010, Volume: 23, Issue:3

    Topics: Adolescent; Age Factors; Alcohol Drinking; Alcoholism; Animals; Brain; Cognition Disorders; Critical Period, Psychological; Disease Models, Animal; Dopamine; Exploratory Behavior; Female; Humans; Male; Motivation; Nerve Net; Neurogenesis; Reward; Risk Factors; Risk-Taking

2010
Nicotine addiction and nicotinic receptors: lessons from genetically modified mice.
    Nature reviews. Neuroscience, 2010, Volume: 11, Issue:6

    Topics: Animals; Behavior, Animal; Central Nervous System; Disease Models, Animal; Gene Expression; Humans; Mice; Mice, Transgenic; Models, Biological; Models, Molecular; Neural Pathways; Nicotine; Protein Subunits; Receptors, Nicotinic; Reward; Tobacco Use Disorder

2010
Animal models of cannabinoid reward.
    British journal of pharmacology, 2010, Volume: 160, Issue:3

    Topics: Animals; Cannabinoid Receptor Modulators; Cannabinoids; Disease Models, Animal; Drug Discovery; Drug Evaluation, Preclinical; Humans; Reward; Self Administration; Substance-Related Disorders

2010
GABAB receptors and depression. Current status.
    Advances in pharmacology (San Diego, Calif.), 2010, Volume: 58

    Topics: Animals; Antidepressive Agents; Cognition; Depression; Disease Models, Animal; Humans; Receptors, GABA-B; Reward

2010
Neuroethics of deep brain stimulation for mental disorders: brain stimulation reward in humans.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:9

    Topics: Animals; Deep Brain Stimulation; Disease Models, Animal; History, 20th Century; History, 21st Century; Humans; Models, Animal; Neurocognitive Disorders; Rats; Reward

2010
The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology.
    Molecular psychiatry, 2010, Volume: 15, Issue:12

    Topics: Adolescent; Animals; Behavioral Research; Brain; Brain Mapping; Disease Models, Animal; Emotions; Genome-Wide Association Study; Humans; Impulsive Behavior; Individuality; Mental Disorders; Patient Selection; Pleasure; Reward

2010
The paradox of drug taking: the role of the aversive effects of drugs.
    Physiology & behavior, 2011, Apr-18, Volume: 103, Issue:1

    Topics: Animals; Avoidance Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Eating; Humans; Models, Psychological; Rats; Reward; Species Specificity; Substance-Related Disorders

2011
Drug-sensitive reward in crayfish: an invertebrate model system for the study of SEEKING, reward, addiction, and withdrawal.
    Neuroscience and biobehavioral reviews, 2011, Volume: 35, Issue:9

    Topics: Amphetamine-Related Disorders; Animals; Astacoidea; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Morphine Dependence; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders

2011
Identification of new drug targets and biomarkers related to obesity and eating disorders: an approach based on reward deficit and addiction.
    Current pharmaceutical design, 2011, Volume: 17, Issue:5

    Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Feeding and Eating Disorders; Genomics; Humans; Models, Neurological; Molecular Targeted Therapy; Neural Pathways; Obesity; Proteomics; Reward; Substance-Related Disorders

2011
Feeding and reward: perspectives from three rat models of binge eating.
    Physiology & behavior, 2011, Jul-25, Volume: 104, Issue:1

    Topics: Animals; Bulimia; Disease Models, Animal; Feeding Behavior; Food Preferences; Rats; Reward

2011
The challenge of studying parallel behaviors in humans and animal models.
    Current topics in behavioral neurosciences, 2013, Volume: 13

    Topics: Alcohols; Animals; Behavior, Addictive; Conditioning, Classical; Conditioning, Operant; Disease Models, Animal; Humans; Impulsive Behavior; Phenotype; Reward; Self Administration

2013
Theoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit disorder.
    Current topics in behavioral neurosciences, 2013, Volume: 13

    Topics: Alcoholism; Animals; Brain; Corticotropin-Releasing Hormone; Disease Models, Animal; Humans; Impulsive Behavior; Models, Biological; Reward

2013
Dysregulation of brain reward systems in eating disorders: neurochemical information from animal models of binge eating, bulimia nervosa, and anorexia nervosa.
    Neuropharmacology, 2012, Volume: 63, Issue:1

    Topics: Animals; Anorexia Nervosa; Brain; Bulimia; Bulimia Nervosa; Disease Models, Animal; Feeding and Eating Disorders; Humans; Reward

2012
[Connectomics of orexin-producing neurons: analysis using mouse models].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2011, Volume: 31, Issue:5-6

    Topics: Animals; Arousal; Disease Models, Animal; Emotions; Energy Metabolism; Feeding Behavior; Humans; Hypothalamus; Intracellular Signaling Peptides and Proteins; Mice; Narcolepsy; Neurons; Neuropeptides; Orexin Receptors; Orexins; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reward; Sleep; Wakefulness

2011
Positron emission tomography molecular imaging of dopaminergic system in drug addiction.
    Anatomical record (Hoboken, N.J. : 2007), 2012, Volume: 295, Issue:5

    Topics: Animals; Behavior, Addictive; Brain; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Heroin Dependence; Humans; Neural Pathways; Neuroimaging; Positron-Emission Tomography; Receptors, Dopamine; Reinforcement, Psychology; Reward; Signal Transduction; Substance-Related Disorders; Time Factors

2012
Schizophrenia in translation: dissecting motivation in schizophrenia and rodents.
    Schizophrenia bulletin, 2012, Volume: 38, Issue:6

    Topics: Anhedonia; Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Humans; Mice; Motivation; Receptors, Dopamine D2; Reward; Schizophrenia; Schizophrenic Psychology

2012
Study of cannabinoid dependence in animals.
    Pharmacology & therapeutics, 2002, Volume: 95, Issue:2

    Topics: Animals; Brain; Cannabinoids; Discrimination Learning; Disease Models, Animal; Drug Tolerance; Marijuana Abuse; Receptors, Cannabinoid; Receptors, Drug; Reinforcement Schedule; Reward; Self Administration; Substance Withdrawal Syndrome

2002
Changes in the immune system in rodent models of depression.
    The international journal of neuropsychopharmacology, 2002, Volume: 5, Issue:4

    Topics: Amnesia; Animals; Antidepressive Agents; Anxiety; Brain; Cytokines; Depressive Disorder; Disease Models, Animal; Humans; Immune System; Mice; Olfactory Bulb; Rats; Reward; Stress, Psychological

2002
Alcoholism: allostasis and beyond.
    Alcoholism, clinical and experimental research, 2003, Volume: 27, Issue:2

    Topics: Alcoholism; Amygdala; Animals; Arousal; Brain Mapping; Corticotropin-Releasing Hormone; Disease Models, Animal; Ethanol; Humans; Motivation; Nerve Net; Neuropeptide Y; Prosencephalon; Reward; Substance Withdrawal Syndrome

2003
The pre-clinical behavioural pharmacology of 3,4-methylenedioxymethamphetamine (MDMA).
    Neuroscience and biobehavioral reviews, 2003, Volume: 27, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Carrier Proteins; Conditioning, Psychological; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hallucinogens; Illicit Drugs; Membrane Glycoproteins; Membrane Transport Proteins; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Reward; Serotonin Plasma Membrane Transport Proteins

2003
The neural circuitry of reward and its relevance to psychiatric disorders.
    Current psychiatry reports, 2004, Volume: 6, Issue:5

    Topics: Animals; Animals, Laboratory; Brain; Disease Models, Animal; Humans; Magnetic Resonance Imaging; Mental Disorders; Positron-Emission Tomography; Receptors, Dopamine; Reward

2004
Novelty reward as a measure of anhedonia.
    Neuroscience and biobehavioral reviews, 2005, Volume: 29, Issue:4-5

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Depression; Disease Models, Animal; Exploratory Behavior; Humans; Nicotine; Nicotinic Agonists; Reward; Substance Withdrawal Syndrome; Weights and Measures

2005
Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS.
    Neuropsychobiology, 2005, Volume: 52, Issue:2

    Topics: Animals; Behavior, Animal; Brain Chemistry; Depression; Disease Models, Animal; Food Preferences; Humans; Individuality; Mice; Neurobiology; Rats; Reward; Stress, Physiological

2005
[Evaluation of the rewarding effect of drug by conditioned place preference paradigm: its bases and applications].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2005, Volume: 126, Issue:1

    Topics: Animals; Central Nervous System Agents; Conditioning, Psychological; Disease Models, Animal; Humans; Reinforcement, Psychology; Reward; Self Administration; Substance-Related Disorders

2005
[Drug-craving animal models and mechanisms].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2005, Volume: 126, Issue:1

    Topics: Acetylcholine; Animals; Cannabinoid Receptor Modulators; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine; Glutamine; Norepinephrine; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Reward; Stress, Physiological; Substance-Related Disorders

2005
Reward-based decision-making and aging.
    Brain research bulletin, 2005, Nov-15, Volume: 67, Issue:5

    Topics: Aging; Animals; Brain; Cognition Disorders; Decision Making; Disease Models, Animal; Humans; Learning Disabilities; Memory Disorders; Neural Pathways; Reward

2005
Behavioural assessment of drug reinforcement and addictive features in rodents: an overview.
    Addiction biology, 2006, Volume: 11, Issue:1

    Topics: Alcoholism; Animals; Association Learning; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Models, Psychological; Motivation; Reinforcement Schedule; Reward; Rodentia; Self Stimulation; Substance Withdrawal Syndrome; Substance-Related Disorders; Wit and Humor as Topic

2006
An endocannabinoid mechanism in relapse to drug seeking: a review of animal studies and clinical perspectives.
    Brain research reviews, 2007, Volume: 53, Issue:1

    Topics: Animals; Brain; Cannabinoid Receptor Modulators; Disease Models, Animal; Endocannabinoids; Humans; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Secondary Prevention; Substance Withdrawal Syndrome; Substance-Related Disorders

2007
The role of dopamine in the pathophysiology of depression.
    Archives of general psychiatry, 2007, Volume: 64, Issue:3

    Topics: Affective Symptoms; Animals; Bipolar Disorder; Brain; Cerebral Cortex; Depressive Disorder, Major; Disease Models, Animal; Dopamine; Down-Regulation; Humans; Positron-Emission Tomography; Receptors, Dopamine; Reward; Serotonin; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon

2007
Running is rewarding and antidepressive.
    Physiology & behavior, 2007, Sep-10, Volume: 92, Issue:1-2

    Topics: Animals; Behavior, Addictive; Cell Proliferation; Depression; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Reward; Running

2007
Stress, dysregulation of drug reward pathways, and the transition to drug dependence.
    The American journal of psychiatry, 2007, Volume: 164, Issue:8

    Topics: Animals; Behavior, Addictive; Brain; Corticotropin-Releasing Hormone; Disease Models, Animal; Electrodes, Implanted; Hydrocortisone; Hypothalamus; Illicit Drugs; Models, Neurological; Prolactin; Rats; Reinforcement, Psychology; Reward; Self Administration; Stress, Physiological; Substance-Related Disorders

2007
Behavioural and physiological effects of electrical stimulation in the nucleus accumbens: a review.
    Acta neurochirurgica. Supplement, 2007, Volume: 97, Issue:Pt 2

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Eating; Electric Stimulation; Exploratory Behavior; Humans; Nucleus Accumbens; Obsessive-Compulsive Disorder; Reward

2007
The role of acetylcholine in cocaine addiction.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:8

    Topics: Acetylcholine; Adaptation, Psychological; Animals; Cocaine; Cocaine-Related Disorders; Cognition; Disease Models, Animal; Humans; Learning; Memory; Neostriatum; Parasympathetic Nervous System; Reward

2008
A final common pathway for depression? Progress toward a general conceptual framework.
    Neuroscience and biobehavioral reviews, 2008, Volume: 32, Issue:3

    Topics: Adrenal Cortex Hormones; Animals; Antidepressive Agents; Brain Mapping; Cytokines; Depressive Disorder; Disease Models, Animal; Humans; Mice; Motivation; Nerve Growth Factors; Neural Pathways; Reward; Stress, Psychological

2008
Neuropsychotoxicity of abused drugs: involvement of matrix metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-2 in methamphetamine-induced behavioral sensitization and reward in rodents.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Disease Models, Animal; Dopamine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Methamphetamine; Mice; Mice, Knockout; Nucleus Accumbens; Oligonucleotides, Antisense; Protease Inhibitors; Reward; Rodentia; Tissue Inhibitor of Metalloproteinase-2; Up-Regulation

2008
Alcohol, the reward system and dependence.
    EXS, 1994, Volume: 71

    Topics: Alcoholism; Animals; Brain; Disease Models, Animal; Endorphins; Humans; Neurotransmitter Agents; Rats; Reinforcement, Psychology; Reward

1994
Genetic animal models of alcohol and drug abuse.
    Science (New York, N.Y.), 1994, Jun-17, Volume: 264, Issue:5166

    Topics: Alcoholism; Animals; Animals, Genetically Modified; Chromosome Mapping; Disease Models, Animal; Ethanol; Genetic Techniques; Mice; Mice, Inbred Strains; Oligonucleotides, Antisense; Rats; Rats, Inbred Strains; Reward; Substance-Related Disorders

1994
Neuroscience of addiction.
    Neuron, 1998, Volume: 21, Issue:3

    Topics: Animals; Brain; Disease Models, Animal; Gene Expression Regulation; Humans; Models, Neurological; Neurons; Neurotransmitter Agents; Psychotropic Drugs; Reward; Substance-Related Disorders; Synapses

1998
Mechanisms of action of drugs of abuse on the developing fetal brain.
    Clinics in perinatology, 1999, Volume: 26, Issue:1

    Topics: Alcoholism; Animals; Brain; Child; Child Development; Child Rearing; Cocaine; Cocaine-Related Disorders; Confounding Factors, Epidemiologic; Disease Models, Animal; Ethanol; Female; Fetus; Humans; Illicit Drugs; Narcotics; Nutritional Physiological Phenomena; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reinforcement, Psychology; Reward; Substance-Related Disorders

1999
Time flies like an arrow. Fruit flies like crack?
    The pharmacogenomics journal, 2001, Volume: 1, Issue:2

    Topics: Animals; Circadian Rhythm; Cocaine-Related Disorders; Disease Models, Animal; Drosophila melanogaster; Reward; Substance-Related Disorders; Tyramine

2001
Cannabinoid addiction: behavioral models and neural correlates.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9

    Topics: Animals; Behavior, Addictive; Cannabinoids; Disease Models, Animal; Dopamine; Drug Tolerance; Humans; Marijuana Abuse; Opioid Peptides; Receptors, Cannabinoid; Receptors, Drug; Reinforcement, Psychology; Reward

2002
Reward and abuse of opiates.
    Pharmacology & toxicology, 1992, Volume: 71, Issue:2

    Topics: Animals; Behavior, Addictive; Brain; Disease Models, Animal; Dopamine; Humans; Narcotics; Reinforcement, Psychology; Reward; Self Administration; Substance-Related Disorders

1992
Chronic mild stress-induced anhedonia: a realistic animal model of depression.
    Neuroscience and biobehavioral reviews, 1992,Winter, Volume: 16, Issue:4

    Topics: Animals; Depressive Disorder; Disease Models, Animal; Reward; Stress, Psychological

1992

Trials

1 trial(s) available for s,n,n'-tripropylthiocarbamate and Disease Models, Animal

ArticleYear
Changes in morphine reward in a model of neuropathic pain.
    Behavioural pharmacology, 2013, Volume: 24, Issue:3

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Conditioning, Operant; Disease Models, Animal; Hyperalgesia; Male; Morphine; Neuralgia; Pain Threshold; Rats; Rats, Long-Evans; Reward; Time Factors

2013

Other Studies

463 other study(ies) available for s,n,n'-tripropylthiocarbamate and Disease Models, Animal

ArticleYear
Maternal separation alters the reward system of activity-based anorexia rats.
    Psychoneuroendocrinology, 2021, Volume: 133

    Topics: Animals; Anorexia; Anxiety; Disease Models, Animal; Dopamine; Dorsal Raphe Nucleus; Female; Male; Maternal Deprivation; Neurons; Orexins; Pars Compacta; Rats; Reward; Serotonin; Ventral Tegmental Area

2021
Role of cytokine and neurotrophic factors in nicotine addiction in the conditioned place preference paradigm.
    Neuroscience letters, 2021, 11-01, Volume: 764

    Topics: Animals; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Corpus Striatum; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Humans; Injections, Intraperitoneal; Interleukin-10; Interleukin-1beta; Male; Mice; Neuroinflammatory Diseases; Nicotine; Prefrontal Cortex; Reward; Tobacco Use Disorder

2021
Antagonism of GluK1-containing kainate receptors reduces ethanol consumption by modulating ethanol reward and withdrawal.
    Neuropharmacology, 2021, 11-01, Volume: 199

    Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Isoquinolines; Mice; Receptors, Ionotropic Glutamate; Receptors, Kainic Acid; Reward; Substance Withdrawal Syndrome

2021
Progressive impairments in executive function in the APP/PS1 model of Alzheimer's disease as measured by translatable touchscreen testing.
    Neurobiology of aging, 2021, Volume: 108

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Disease Progression; Executive Function; Mice, Transgenic; Neuropsychological Tests; Presenilin-1; Reward; Touch; Visual Perception

2021
Wisket rat model of schizophrenia: Impaired motivation and, altered brain structure, but no anhedonia.
    Physiology & behavior, 2022, 02-01, Volume: 244

    Topics: Anhedonia; Animals; Brain; Disease Models, Animal; Humans; Motivation; Rats; Reward; Schizophrenia

2022
Environmental enrichment and intranasal oxytocin administration reverse maternal separation-induced impairments of prosocial choice behavior.
    Pharmacology, biochemistry, and behavior, 2022, Volume: 213

    Topics: Administration, Intranasal; Altruism; Animals; Behavior, Animal; Choice Behavior; Cognition; Disease Models, Animal; Female; Housing, Animal; Male; Maternal Deprivation; Oxytocin; Rats; Rats, Wistar; Reward; Social Behavior

2022
Morphine Exposure Reduces Nicotine-Induced Upregulation of Nicotinic Receptors and Decreases Volitional Nicotine Intake in a Mouse Model.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2022, 07-13, Volume: 24, Issue:8

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Morphine; Nicotine; Receptors, Nicotinic; Reward; Up-Regulation; Ventral Tegmental Area

2022
Waving Through the Window: A Model of Volitional Social Interaction in Female Mice.
    Biological psychiatry, 2022, 06-01, Volume: 91, Issue:11

    Topics: Adolescent; Animals; Conditioning, Operant; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred C57BL; Reinforcement Schedule; Reward; Social Behavior; Social Interaction

2022
Rabbits can be conditioned in a food-induced place preference paradigm.
    Brain research, 2022, 04-15, Volume: 1781

    Topics: Animals; Conditioning, Classical; Disease Models, Animal; Female; Food Preferences; Humans; Mammals; Mice; Motivation; Rabbits; Rats; Reward

2022
Chronic experience with unpredictable food availability promotes food reward, overeating, and weight gain in a novel animal model of food insecurity.
    Appetite, 2022, 09-01, Volume: 176

    Topics: Animals; Disease Models, Animal; Female; Food Insecurity; Humans; Hyperphagia; Obesity; Rats; Reward; Weight Gain

2022
Acupuncture attenuates comorbid anxiety- and depressive-like behaviors of atopic dermatitis through modulating neuroadaptation in the brain reward circuit in mice.
    Biological research, 2022, Sep-10, Volume: 55, Issue:1

    Topics: Acupuncture Therapy; Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Dermatitis, Atopic; Disease Models, Animal; Mice; Reward

2022
Chronic methamphetamine exposure exerts few effects on the iTat mouse model of HIV, but blocks Tat expression-induced slowed reward retrieval.
    Behavioural brain research, 2023, 02-02, Volume: 437

    Topics: Amphetamine-Related Disorders; Animals; Calbindins; Disease Models, Animal; HIV Infections; Humans; Methamphetamine; Mice; Mice, Transgenic; Reward; tat Gene Products, Human Immunodeficiency Virus

2023
Voluntary and forced exposure to ethanol vapor produces similar escalation of alcohol drinking but differential recruitment of brain regions related to stress, habit, and reward in male rats.
    Neuropharmacology, 2023, 01-01, Volume: 222

    Topics: Alcohol Drinking; Alcoholism; Animals; Blood Alcohol Content; Central Amygdaloid Nucleus; Disease Models, Animal; Ethanol; Habits; Male; Rats; Reward

2023
Aberrant habit formation in the Sapap3-knockout mouse model of obsessive-compulsive disorder.
    Scientific reports, 2019, 08-19, Volume: 9, Issue:1

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Genotype; Habits; Locomotion; Mice; Mice, Knockout; Nerve Tissue Proteins; Obsessive-Compulsive Disorder; Phenotype; Reward

2019
Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
    Behavioural brain research, 2020, 01-13, Volume: 377

    Topics: Animals; Behavior, Animal; Cognition; Decision Making; Delay Discounting; Disease Models, Animal; Gambling; Impulsive Behavior; Individuality; Locomotion; Male; Phenotype; Probability Learning; Rats; Rats, Inbred Strains; Reward; Social Behavior; Spatial Behavior

2020
Deletion of mu opioid receptors reduces palatable solution intake in a mouse model of binge eating.
    Behavioural pharmacology, 2020, Volume: 31, Issue:2&3

    Topics: Animals; Binge-Eating Disorder; Body Weight; Bulimia; Disease Models, Animal; Eating; Energy Intake; Feeding Behavior; Female; Food Preferences; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Opioid, mu; Reward; Sucrose

2020
Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Exploratory Behavior; Female; Male; Mice; Mice, Transgenic; Nucleus Accumbens; Prefrontal Cortex; Reward; Sex Characteristics; Stress, Psychological

2020
Reward sensitivity deficits in a rat model of compulsive eating behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:4

    Topics: Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Food Addiction; Male; Microdialysis; Rats; Rats, Wistar; Reward

2020
Voluntary exercise is motivated by ghrelin, possibly related to the central reward circuit.
    The Journal of endocrinology, 2020, 01-01, Volume: 244, Issue:1

    Topics: Animals; Disease Models, Animal; Dopamine; Feeding Behavior; Ghrelin; Motivation; Motor Activity; Obesity; Rats; Receptors, Ghrelin; Reward

2020
Enhanced methamphetamine-induced conditioned place preference in risk-taking rats.
    Behavioural brain research, 2020, 01-27, Volume: 378

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Choice Behavior; Conditioning, Psychological; Disease Models, Animal; Disease Susceptibility; Individuality; Male; Methamphetamine; Rats; Rats, Long-Evans; Reward; Risk-Taking; Substance-Related Disorders

2020
Age-dependent emergence of neurophysiological and behavioral abnormalities in progranulin-deficient mice.
    Alzheimer's research & therapy, 2019, 10-22, Volume: 11, Issue:1

    Topics: Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Frontotemporal Dementia; Male; Mice; Mice, Knockout; Progranulins; Reward

2019
Reward and immune responses in adolescent females following experimental traumatic brain injury.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain Injuries, Traumatic; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Estradiol; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroprotection; Progesterone; Reward; Sex Characteristics

2020
Cognitive performance of the MAM-E17 schizophrenia model rats in different age-periods.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Age Factors; Animals; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Female; Hippocampus; Male; Maze Learning; Memory, Short-Term; Methylazoxymethanol Acetate; Neurotoxins; Rats; Rats, Wistar; Reward; Schizophrenia; Sexual Maturation

2020
Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.
    Communications biology, 2019, Volume: 2

    Topics: alpha-Synuclein; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Disease Susceptibility; Dopaminergic Neurons; Extracellular Space; Immunohistochemistry; Male; Mesencephalon; Mice; Mice, Knockout; Models, Biological; Motivation; Motor Activity; Reward; Signal Transduction

2019
Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Animals; Apomorphine; Behavior, Animal; Citalopram; Conflict, Psychological; Disease Models, Animal; Dopamine Agonists; Feedback, Psychological; Motivation; Obsessive-Compulsive Disorder; Reward; Selective Serotonin Reuptake Inhibitors; Social Behavior; Zebrafish

2020
Chronic corticosterone administration induces negative valence and impairs positive valence behaviors in mice.
    Translational psychiatry, 2019, 12-10, Volume: 9, Issue:1

    Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Corticosterone; Disease Models, Animal; Learning; Male; Mice; Mice, Inbred C57BL; Reward; Steroids

2019
Differential effects of prior stress on conditioned inhibition of fear and fear extinction.
    Behavioural brain research, 2020, 03-02, Volume: 381

    Topics: Animals; Conditioning, Psychological; Disease Models, Animal; Extinction, Psychological; Fear; Inhibition, Psychological; Rats; Rats, Long-Evans; Reward; Stress Disorders, Post-Traumatic; Stress, Psychological

2020
Instrumental learning in a mouse model for obsessive-compulsive disorder: Impaired habit formation in Sapap3 mutants.
    Neurobiology of learning and memory, 2020, Volume: 168

    Topics: Animals; Conditioning, Operant; Disease Models, Animal; Female; Habits; Male; Mice, Knockout; Nerve Tissue Proteins; Obsessive-Compulsive Disorder; Reward

2020
Lisdexamfetamine suppresses instrumental and consummatory behaviors supported by foods with varying degrees of palatability: Exploration of a binge-like eating model.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 189

    Topics: Animals; Binge-Eating Disorder; Body Weight; Bulimia; Chocolate; Conditioning, Operant; Consummatory Behavior; Disease Models, Animal; Eating; Feeding Behavior; Female; Food Preferences; Lisdexamfetamine Dimesylate; Prodrugs; Rats; Rats, Wistar; Reward; Treatment Outcome

2020
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
    Nature communications, 2020, 01-16, Volume: 11, Issue:1

    Topics: Aminopyridines; Animals; Chemokine CX3CL1; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Electronic Nicotine Delivery Systems; Female; Gene Expression Regulation; Male; Microglia; Minocycline; Nicotine; Phenotype; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration; Synaptophysin

2020
Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model.
    Neuroscience letters, 2020, 03-16, Volume: 721

    Topics: Animals; Conditioning, Psychological; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Rats, Wistar; Reward; Saccharin; Self Administration; Species Specificity; Sweetening Agents

2020
Heightened reward response is associated with HCN2 overexpression in the ventral tegmental area in morphine-sensitized rats.
    Behavioural pharmacology, 2020, Volume: 31, Issue:2&3

    Topics: Animals; Bipolar Disorder; Brain; Disease Models, Animal; Dopamine; Gene Expression; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Morphine; Nucleus Accumbens; Potassium Channels; Rats; Rats, Sprague-Dawley; Reward; Transcriptome; Ventral Tegmental Area

2020
Behavioral and neuroimmune characterization of resilience to social stress: Rewarding effects of cocaine.
    Adicciones, 2021, Nov-05, Volume: 33, Issue:4

    Topics: Animals; Cocaine; Disease Models, Animal; Humans; Male; Mice; Reward; Stress, Psychological

2021
Maternal immune activation is associated with a lower number of dopamine receptor 3-expressing granulocytes with no alterations in cocaine reward, resistance to extinction or cue-induced reinstatement.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 193

    Topics: Animals; Biomarkers; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Female; Granulocytes; Leukocyte Count; Lipopolysaccharides; Male; Pregnancy; Prepulse Inhibition; Rats; Rats, Inbred Lew; Receptor, Cannabinoid, CB2; Receptors, Dopamine D3; Reward; Schizophrenia; Self Administration; T-Lymphocytes

2020
Checking responses of goal- and sign-trackers are differentially affected by threat in a rodent analog of obsessive-compulsive disorder.
    Learning & memory (Cold Spring Harbor, N.Y.), 2020, Volume: 27, Issue:5

    Topics: Animals; Anxiety; Appetitive Behavior; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Conditioning, Operant; Disease Models, Animal; Fear; Goals; Male; Motivation; Obsessive-Compulsive Disorder; Rats; Reward

2020
Maternal exercise during gestation and lactation decreases high-fat diet preference by altering central reward system gene expression in adult female offspring from high-fat fed dams.
    Behavioural brain research, 2020, 07-15, Volume: 390

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Diet, High-Fat; Disease Models, Animal; Female; Food Preferences; Gene Expression; Hypothalamus; Lactation; Maternal Nutritional Physiological Phenomena; Physical Conditioning, Animal; Pregnancy; Pro-Opiomelanocortin; Rats, Sprague-Dawley; Reward

2020
Increased Responding for Alcohol and Resistance to Aversion in Female Mice.
    Alcoholism, clinical and experimental research, 2020, Volume: 44, Issue:7

    Topics: Alcohol Drinking; Animals; Aversive Agents; Behavior, Animal; Central Nervous System Depressants; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Ethanol; Female; Male; Mice; Motivation; Quinine; Reward; Self Administration; Sex Factors

2020
Molecular mechanism of reward treatment ameliorating chronic stress-induced depressive-like behavior assessed by sequencing miRNA and mRNA in medial prefrontal cortex.
    Biochemical and biophysical research communications, 2020, 07-30, Volume: 528, Issue:3

    Topics: Animals; Depression; Disease Models, Animal; Female; Gene Expression Profiling; Gene Regulatory Networks; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Prefrontal Cortex; Reward; RNA, Messenger; Signal Transduction; Social Behavior; Stress, Physiological

2020
Brain stimulation rewarding experience attenuates neonatal clomipramine-induced adulthood anxiety by reversal of pathological changes in the amygdala.
    Progress in neuro-psychopharmacology & biological psychiatry, 2020, 12-20, Volume: 103

    Topics: Amygdala; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Anxiety; Biogenic Monoamines; Brain; Clomipramine; Corticosterone; Depression; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Female; Male; Pregnancy; Rats; Rats, Wistar; Reward; Self Stimulation

2020
Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the basolateral amygdala.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:11

    Topics: Animals; Basolateral Nuclear Complex; Conditioning, Psychological; Corticosterone; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Humans; Male; Mifepristone; Morphine; Nerve Net; Nucleus Accumbens; Opioid-Related Disorders; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Receptors, Glucocorticoid; Reward; Signal Transduction; Stereotaxic Techniques; Stress, Psychological

2020
Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression.
    Scientific reports, 2020, 06-23, Volume: 10, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Corticosterone; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motivation; Photoperiod; Reversal Learning; Reward; Sensory Gating

2020
The impact of GABA
    European journal of pharmacology, 2020, Sep-15, Volume: 883

    Topics: Animals; Baclofen; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Depression; Disease Models, Animal; Drug-Seeking Behavior; GABA-B Receptor Agonists; Male; Organophosphorus Compounds; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Reinforcement, Psychology; Reward

2020
Nicotinic Antagonist UFR2709 Inhibits Nicotine Reward and Decreases Anxiety in Zebrafish.
    Molecules (Basel, Switzerland), 2020, Jun-30, Volume: 25, Issue:13

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzoates; Disease Models, Animal; Nicotine; Nicotinic Antagonists; Pyrrolidines; Receptors, Nicotinic; Reward; Swimming; Zebrafish

2020
Decreased Neuronal Excitability in Medial Prefrontal Cortex during Morphine Withdrawal is associated with enhanced SK channel activity and upregulation of small GTPase Rac1.
    Theranostics, 2020, Volume: 10, Issue:16

    Topics: Action Potentials; Animals; Conditioning, Psychological; Disease Models, Animal; Humans; Male; Morphine; Neurons; Opioid-Related Disorders; Prefrontal Cortex; rac1 GTP-Binding Protein; Rats; Reward; Small-Conductance Calcium-Activated Potassium Channels; Substance Withdrawal Syndrome; Up-Regulation

2020
Selective breeding for high alcohol preference is associated with increased sensitivity to cannabinoid reward within the nucleus accumbens shell.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 197

    Topics: Alcoholism; Animals; Cannabinoids; Conditioning, Operant; Disease Models, Animal; Ethanol; Female; Marijuana Abuse; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Reward; Selective Breeding; Self Administration

2020
Selective Deficits in Contingency-Driven Ethanol Seeking Following Chronic Ethanol Exposure in Male Mice.
    Alcoholism, clinical and experimental research, 2020, Volume: 44, Issue:9

    Topics: Administration, Inhalation; Alcoholism; Animals; Behavior, Animal; Central Nervous System Depressants; Disease Models, Animal; Drug-Seeking Behavior; Ethanol; Male; Mice; Reward; Self Administration; Sucrose; Sweetening Agents

2020
Meranzin hydrate elicits antidepressant effects and restores reward circuitry.
    Behavioural brain research, 2021, 02-01, Volume: 398

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Coumarins; Dentate Gyrus; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hypothalamo-Hypophyseal System; Male; Rats; Rats, Wistar; Reward; Stress, Psychological

2021
Conditioned Place Preference (CPP) in Rats: From Conditioning to Reinstatement Test.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2201

    Topics: Analgesics, Opioid; Animals; Behavior Control; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Male; Morphine; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reward

2021
Analysis of Opioid-Seeking Behavior Through the Intravenous Self-Administration Reinstatement Model in Rats.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2201

    Topics: Administration, Intravenous; Analgesics, Opioid; Animals; Behavior Control; Behavior, Addictive; Conditioning, Operant; Cues; Disease Models, Animal; Drug-Seeking Behavior; Heroin; Infusions, Intravenous; Male; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration; Substance-Related Disorders

2021
Central CRF and acute stress differentially modulate probabilistic reversal learning in male and female rats.
    Behavioural brain research, 2021, 01-15, Volume: 397

    Topics: Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Discrimination Learning; Disease Models, Animal; Female; Injections, Intraventricular; Male; Motivation; Probability Learning; Rats; Reinforcement, Psychology; Restraint, Physical; Reversal Learning; Reward; Sex Characteristics; Sex Factors; Stress, Psychological

2021
Indirect exposure to socially defeated conspecifics using recorded video activates the HPA axis and reduces reward sensitivity in mice.
    Scientific reports, 2020, 10-09, Volume: 10, Issue:1

    Topics: Anhedonia; Animals; Brain; Choice Behavior; Corticosterone; Depression; Disease Models, Animal; Empathy; Humans; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Neurons; Photic Stimulation; Proto-Oncogene Proteins c-fos; Reward; Social Defeat; Stress, Psychological; Video Recording; Vision, Ocular; Visual Perception

2020
Sign tracking predicts cue-induced but not drug-primed reinstatement to methamphetamine seeking in rats: Effects of oxytocin treatment.
    Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:11

    Topics: Amphetamine-Related Disorders; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Classical; Cues; Disease Models, Animal; Extinction, Psychological; Female; Male; Methamphetamine; Motivation; Oxytocin; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Reward

2020
Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model.
    Cell, 2020, 11-12, Volume: 183, Issue:4

    Topics: Action Potentials; Aging; Animals; Behavior, Animal; Biomarkers; Corpus Striatum; Discrimination Learning; Disease Models, Animal; Huntington Disease; Interneurons; Learning; Mice, Transgenic; Models, Neurological; Nerve Net; Parvalbumins; Photometry; Reward; Task Performance and Analysis

2020
A naturalistic method to test depression: Anticipation of play.
    Behavioural brain research, 2021, 02-01, Volume: 398

    Topics: Age Factors; Animals; Anticipation, Psychological; Depression; Disease Models, Animal; Male; Motivation; Neuropsychological Tests; Play and Playthings; Rats; Rats, Inbred WKY; Rats, Wistar; Reward; Social Behavior; Vocalization, Animal

2021
Reward motivation and cognitive flexibility in tau null-mutation mice.
    Neurobiology of aging, 2021, Volume: 100

    Topics: Alzheimer Disease; Animals; Cognition; Conditioning, Operant; Disease Models, Animal; Female; Frontotemporal Dementia; Learning; Loss of Function Mutation; Male; Mice, Knockout; Motivation; Reward; tau Proteins; Tauopathies

2021
The irrelevancy of the inter-trial interval in delay-discounting experiments on an animal model of ADHD.
    Behavioural brain research, 2021, 06-25, Volume: 408

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Delay Discounting; Disease Models, Animal; Impulsive Behavior; Male; Rats, Inbred SHR; Rats, Inbred WKY; Reward; Time Factors

2021
Female mice are more prone to develop an addictive-like phenotype for sugar consumption.
    Scientific reports, 2021, 04-01, Volume: 11, Issue:1

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Binge-Eating Disorder; Body Weight; Conditioning, Operant; Dietary Sugars; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Motivation; Phenotype; Reward; Self Administration; Sex Factors

2021
Sign Tracking in an Enriched Environment: A Potential Ecologically Relevant Animal Model of Adaptive Behavior Change.
    Cognitive, affective & behavioral neuroscience, 2022, Volume: 22, Issue:4

    Topics: Adaptation, Psychological; Animals; Behavior, Animal; Cues; Disease Models, Animal; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward

2022
Resurgence of alcohol seeking following abstinence induced by punishment in male and female rats.
    Behavioural brain research, 2021, 07-23, Volume: 410

    Topics: Alcohol Abstinence; Alcoholism; Animals; Behavior, Animal; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Female; Male; Punishment; Rats; Rats, Long-Evans; Reward; Self Administration; Sex Characteristics

2021
Role of acute social stress in the rewarding effects of MDMA in adolescent mice.
    Behavioural brain research, 2021, 07-23, Volume: 410

    Topics: Age Factors; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Classical; Disease Models, Animal; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Social Defeat; Stress, Psychological

2021
Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine.
    Neuroscience letters, 2021, 08-24, Volume: 760

    Topics: Amygdala; Animals; Conditioning, Operant; Disease Models, Animal; Hippocampus; Humans; Interleukin-1beta; Male; Morphine; Morphine Dependence; Neuroinflammatory Diseases; Prefrontal Cortex; Rats; Reward; Saccharin; Signal Transduction

2021
Altering the development of the dopaminergic system through social play in rats: Implications for anxiety, depression, hyperactivity, and compulsivity.
    Neuroscience letters, 2021, 08-24, Volume: 760

    Topics: Animals; Anxiety; Attention Deficit Disorder with Hyperactivity; Depression; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Emotions; Female; Humans; Impulsive Behavior; Male; Obsessive-Compulsive Disorder; Rats; Rats, Transgenic; Reward; Social Behavior

2021
Systemic administration of N-acetylcysteine during the extinction period and on the reinstatement day decreased the maintenance of morphine rewarding properties in the rats.
    Behavioural brain research, 2021, 09-10, Volume: 413

    Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Conditioning, Classical; Disease Models, Animal; Locomotion; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Wistar; Reinforcement, Psychology; Reward

2021
Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment.
    Behavioural brain research, 2021, 09-24, Volume: 414

    Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Drug Tolerance; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Wistar; Reward; RNA, Long Noncoding

2021
Real time monitoring of dopamine release evoked by mitragynine (Kratom): An insight through electrochemical sensor.
    Neuroscience letters, 2021, 10-15, Volume: 763

    Topics: Animals; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electrochemical Techniques; Electrodes; Frontal Lobe; Gene Expression Profiling; Humans; Male; Neurophysiological Monitoring; Rats; Reward; Secologanin Tryptamine Alkaloids; Substance-Related Disorders

2021
Stimulating GABAergic Neurons in the Nucleus Accumbens Core Alters the Trigeminal Neuropathic Pain Responses in a Rat Model of Infraorbital Nerve Injury.
    International journal of molecular sciences, 2021, Aug-05, Volume: 22, Issue:16

    Topics: Animals; Disease Models, Animal; Dopamine; Female; GABAergic Neurons; Glutamic Acid; Maxilla; Nervous System Diseases; Nucleus Accumbens; Optogenetics; Rats; Rats, Sprague-Dawley; Reward; Thalamus; Trigeminal Neuralgia

2021
Does activation of midbrain dopamine neurons promote or reduce feeding?
    International journal of obesity (2005), 2017, Volume: 41, Issue:7

    Topics: Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Eating; Feeding Behavior; Male; Mesencephalon; Neural Pathways; Piperazines; Rats; Reward

2017
Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease.
    Nature communications, 2017, 04-03, Volume: 8

    Topics: Alzheimer Disease; Animals; Apoptosis; Cell Death; Dendritic Spines; Dihydroxyphenylalanine; Disease Models, Animal; Dopaminergic Neurons; Food; Hippocampus; Inflammation; Memory; Mice, Transgenic; Nerve Degeneration; Neuronal Plasticity; Nucleus Accumbens; Plaque, Amyloid; Reward; Selegiline; Ventral Tegmental Area

2017
Brain-Derived Neurotrophic Factor in the Mesolimbic Reward Circuitry Mediates Nociception in Chronic Neuropathic Pain.
    Biological psychiatry, 2017, Oct-15, Volume: 82, Issue:8

    Topics: Animals; Baclofen; Benzazepines; Brain-Derived Neurotrophic Factor; Cardiotonic Agents; Disease Models, Animal; Dopaminergic Neurons; Functional Laterality; GABA-B Receptor Agonists; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Neuralgia; Nociception; Pain Threshold; Proto-Oncogene Proteins c-fos; Pyrimidines; Reward

2017
Evaluation of effect of minocycline on rewarding potential and alcohol relapse in place preference model in mice.
    Neuroscience letters, 2017, 05-10, Volume: 649

    Topics: Alcohol Drinking; Alcoholism; Animals; Conditioning, Classical; Conditioning, Operant; Disease Models, Animal; Ethanol; Extinction, Psychological; Male; Mice; Minocycline; Naltrexone; Reward; Secondary Prevention

2017
Suppression of reward-induced dopamine release in the nucleus accumbens in animal models of depression: Differential responses to drug treatment.
    Neuroscience letters, 2017, 05-22, Volume: 650

    Topics: Animals; Antidepressive Agents; Citalopram; Depression; Disease Models, Animal; Dopamine; Inhibition, Psychological; Male; Maternal Deprivation; Neural Inhibition; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Stress, Psychological; Treatment Outcome

2017
The rewarding effects of ethanol are modulated by binge eating of a high-fat diet during adolescence.
    Neuropharmacology, 2017, Jul-15, Volume: 121

    Topics: Animals; Animals, Newborn; Bulimia; Central Nervous System Depressants; Conditioning, Operant; Diet, High-Fat; Disease Models, Animal; Drug Administration Routes; Ethanol; Locomotion; Male; Mice; Reward; Self Administration; Time Factors

2017
Social stress in early puberty has long-term impacts on impulsive action.
    Behavioral neuroscience, 2017, Volume: 131, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Food Deprivation; Impulsive Behavior; Inhibition, Psychological; Mesocricetus; Psychomotor Performance; Reaction Time; Reward; Stress, Psychological

2017
Re-evaluation of the reward comparison hypothesis for alcohol abuse.
    Behavioural brain research, 2017, 08-14, Volume: 332

    Topics: Alcoholism; Animals; Central Nervous System Depressants; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Male; Models, Psychological; Psychological Tests; Random Allocation; Rats, Wistar; Reward; Saccharin; Space Perception

2017
Opiate exposure state controls dopamine D3 receptor and cdk5/calcineurin signaling in the basolateral amygdala during reward and withdrawal aversion memory formation.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 10-03, Volume: 79, Issue:Pt B

    Topics: Analgesics, Opioid; Animals; Association Learning; Avoidance Learning; Basolateral Nuclear Complex; Calcineurin; Conditioning, Psychological; Cyclin-Dependent Kinase 5; Disease Models, Animal; Heroin; Male; Memory; Opioid-Related Disorders; Ranolazine; Rats, Sprague-Dawley; Receptors, Dopamine D3; Reward; Signal Transduction; Spatial Behavior; Substance Withdrawal Syndrome

2017
Behavioral Inefficiency on a Risky Decision-Making Task in Adulthood after Adolescent Intermittent Ethanol Exposure in Rats.
    Scientific reports, 2017, 07-05, Volume: 7, Issue:1

    Topics: Alcohol Drinking; Animals; Behavior Rating Scale; Decision Making; Disease Models, Animal; Male; Punishment; Rats; Reward; Risk-Taking

2017
Sensitivity to cocaine in adult mice is due to interplay between genetic makeup, early environment and later experience.
    Neuropharmacology, 2017, Volume: 125

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Disease Susceptibility; Dopamine Uptake Inhibitors; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Inbred DBA; Proto-Oncogene Proteins c-fos; Random Allocation; Reward; Spatial Behavior; Species Specificity

2017
Uncertainty exposure causes behavioural sensitization and increases risky decision-making in male rats: toward modelling gambling disorder.
    Journal of psychiatry & neuroscience : JPN, 2017, Volume: 42, Issue:6

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Decision Making; Disease Models, Animal; Gambling; Male; Motor Activity; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Saccharin; Stress, Psychological; Uncertainty

2017
The trait 'pessimism' does not interact with cognitive flexibility but makes rats more vulnerable to stress-induced motivational deficits: Results from the attentional set-shifting task.
    Behavioural brain research, 2017, 09-29, Volume: 335

    Topics: Animals; Attention; Behavior, Animal; Cognition; Cues; Depression; Depressive Disorder; Discrimination, Psychological; Disease Models, Animal; Executive Function; Judgment; Male; Motivation; Optimism; Pessimism; Rats; Rats, Sprague-Dawley; Reward; Stress, Psychological

2017
A preclinical model for identifying rats at risk of alcohol use disorder.
    Scientific reports, 2017, 08-25, Volume: 7, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Animals; Anxiety; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Ethanol; Humans; Male; Rats; Rats, Wistar; Reward; Risk; Self Administration

2017
Chronic treatment with Tempol during acquisition or withdrawal from CPP abolishes the expression of cocaine reward and diminishes oxidative damage.
    Scientific reports, 2017, 09-11, Volume: 7, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cyclic N-Oxides; Disease Models, Animal; Lipid Peroxidation; Male; Nitric Oxide; Nitrites; Oxidative Stress; Prefrontal Cortex; Rats; Reinforcement, Psychology; Reward; Spin Labels; Treatment Outcome

2017
Motivational wheel running reverses cueing behavioural inflexibility in rodents.
    Journal of neural transmission (Vienna, Austria : 1996), 2017, Volume: 124, Issue:12

    Topics: Acoustic Stimulation; Animals; Association Learning; Autism Spectrum Disorder; Cues; Disease Models, Animal; Enzyme Inhibitors; Male; Motivation; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Valproic Acid

2017
Delay discounting as impaired valuation: Delayed rewards in an animal obesity model.
    Journal of the experimental analysis of behavior, 2017, Volume: 108, Issue:2

    Topics: Animals; Conditioning, Operant; Delay Discounting; Disease Models, Animal; Impulsive Behavior; Male; Obesity; Rats, Zucker; Reward

2017
Under the influence: Effects of adolescent ethanol exposure and anxiety on motivation for uncertain gambling-like cues in male and female rats.
    Behavioural brain research, 2018, Jan-30, Volume: 337

    Topics: Alcohol Drinking; Animals; Animals, Newborn; Anxiety; Central Nervous System Depressants; Conditioning, Operant; Cues; Disease Models, Animal; Ethanol; Female; Gambling; Male; Maze Learning; Motivation; Random Allocation; Rats; Rats, Sprague-Dawley; Reward; Sex Factors; Time Factors; Uncertainty

2018
Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine.
    Addiction biology, 2018, Volume: 23, Issue:5

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Limbic Lobe; Male; Mesencephalon; Motivation; Orexin Receptors; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Signal Transduction; Ventral Tegmental Area

2018
Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders.
    Molecular psychiatry, 2018, Volume: 23, Issue:3

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Chromosome Deletion; Corpus Striatum; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Learning; Male; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 3; Motivation; Neurodevelopmental Disorders; Phosphorylation; Reward; Sex Factors; Signal Transduction

2018
Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat.
    Physiology & behavior, 2018, Jan-01, Volume: 183

    Topics: Animals; Animals, Outbred Strains; Anxiety; Bulimia; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corticosterone; Diet, High-Fat; Disease Models, Animal; Dopamine Uptake Inhibitors; Housing, Animal; Leptin; Male; Mice; Random Allocation; Reward; Social Isolation; Spatial Behavior

2018
Instrumental conditioning for food reinforcement in the spontaneously hypertensive rat model of attention deficit hyperactivity disorder.
    BMC research notes, 2017, Oct-30, Volume: 10, Issue:1

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Food; Inhibition, Psychological; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Reinforcement, Psychology; Reward

2017
Dissociating the effects of alternative early-life feeding schedules on the development of adult depression-like phenotypes.
    Scientific reports, 2017, 11-01, Volume: 7, Issue:1

    Topics: Animals; Depression; Depressive Disorder; Disease Models, Animal; Feeding Behavior; Female; Humans; Male; Motivation; Reward; Starlings

2017
Differential use of danger and safety signals in an animal model of anxiety vulnerability: The behavioral economics of avoidance.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 03-02, Volume: 82

    Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Genetic Predisposition to Disease; Male; Motivation; Philosophy; Psychological Tests; Rats, Inbred WKY; Rats, Sprague-Dawley; Reward; Species Specificity

2018
Phencyclidine increased while isolation rearing did not affect progressive ratio responding in rats: Investigating potential models of amotivation in schizophrenia.
    Behavioural brain research, 2019, 05-17, Volume: 364

    Topics: Affect; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Antagonists; Male; Motivation; N-Methylaspartate; Phencyclidine; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Reward; Schizophrenia; Social Isolation

2019
Dissociation of place preference and tolerance responses to sucrose using a dopamine antagonist in the planarian.
    Psychopharmacology, 2018, Volume: 235, Issue:3

    Topics: Animals; Behavior, Addictive; Benzazepines; Cocaine; Conditioning, Classical; Disease Models, Animal; Dopamine Antagonists; Drug Tolerance; Male; Planarians; Reward; Sucrose

2018
Pregabalin induces conditioned place preference in the rat during the early, but not late, stage of neuropathic pain.
    Neuroscience letters, 2018, 03-06, Volume: 668

    Topics: Analgesics; Animals; Conditioning, Classical; Disease Models, Animal; Hyperalgesia; Male; Neuralgia; Pregabalin; Rats; Rats, Sprague-Dawley; Reward

2018
Ketamine blocks bursting in the lateral habenula to rapidly relieve depression.
    Nature, 2018, 02-14, Volume: 554, Issue:7692

    Topics: Action Potentials; Affect; Anhedonia; Animals; Antidepressive Agents; Calcium Channel Blockers; Calcium Channels; Depression; Disease Models, Animal; Habenula; Ketamine; Male; Mice; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Theta Rhythm

2018
Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:8

    Topics: Animals; Behavior, Animal; Bipolar Disorder; CLOCK Proteins; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Male; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Paraventricular Hypothalamic Nucleus; Photoperiod; Reward; Risk-Taking; RNA, Messenger; Seasons

2018
Spared motivational modulation of cognitive effort in a maternal immune activation model of schizophrenia risk.
    Behavioral neuroscience, 2018, Volume: 132, Issue:1

    Topics: Animals; Attention; Cognition; Discrimination, Psychological; Disease Models, Animal; Extinction, Psychological; Female; Male; Motivation; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Rats, Sprague-Dawley; Reward; Schizophrenia; Schizophrenic Psychology

2018
Motivational changes that develop in a mouse model of inflammation-induced depression are independent of indoleamine 2,3 dioxygenase.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Choice Behavior; Conditioning, Operant; Depression; Disease Models, Animal; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Lipopolysaccharides; Mice; Mice, Knockout; Motivation; Reinforcement Schedule; Reward

2019
Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal.
    Brain structure & function, 2018, Volume: 223, Issue:7

    Topics: Animals; Behavior, Animal; Brain; Conditioning, Psychological; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Male; Morphine; Opioid-Related Disorders; Rats, Sprague-Dawley; Reward; Serotonin; Substance Withdrawal Syndrome; Synaptic Transmission; Time Factors; Ultrasonic Waves; Vocalization, Animal

2018
Sex-specific effects of Cacna1c haploinsufficiency on object recognition, spatial memory, and reversal learning capabilities in rats.
    Neurobiology of learning and memory, 2018, Volume: 155

    Topics: Animals; Behavior, Animal; Calcium Channels, L-Type; Disease Models, Animal; Female; Genotype; Haploinsufficiency; Male; Rats, Sprague-Dawley; Recognition, Psychology; Reversal Learning; Reward; Sex Characteristics; Spatial Learning; Spatial Memory

2018
Reward-representing D1-type neurons in the medial shell of the accumbens nucleus regulate palatable food intake.
    International journal of obesity (2005), 2019, Volume: 43, Issue:4

    Topics: Animals; Disease Models, Animal; Feeding Behavior; Female; Male; Neural Pathways; Neurons; Nucleus Accumbens; Pregnancy; Rats; Rats, Wistar; Reward

2019
Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice.
    Neuropharmacology, 2018, Volume: 138

    Topics: Alcohol Drinking; Alcohol-Related Disorders; Animals; Brain; Central Nervous System Depressants; Conditioning, Psychological; Disease Models, Animal; Environment; Ethanol; Housing, Animal; Mice; Oxytocin; Receptors, Oxytocin; Reward; Spatial Behavior

2018
Toward an integrative perspective on the neural mechanisms underlying persistent maladaptive behaviors.
    The European journal of neuroscience, 2018, Volume: 48, Issue:3

    Topics: Animals; Brain; Congresses as Topic; Decision Making; Disease Models, Animal; Humans; Impulsive Behavior; Models, Neurological; Reward

2018
Exploring reward system responsivity in the nucleus accumbens across chronicity of binge eating in female rats.
    The International journal of eating disorders, 2018, Volume: 51, Issue:8

    Topics: Animals; Binge-Eating Disorder; Brain; Disease Models, Animal; Female; Humans; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward

2018
Pituitary adenylate cyclase-activating polypeptide (PACAP) acts in the nucleus accumbens to reduce hedonic drive.
    International journal of obesity (2005), 2019, Volume: 43, Issue:4

    Topics: Animals; Disease Models, Animal; Feeding Behavior; Male; Nucleus Accumbens; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Reward; Sucrose; Taste

2019
Differential effects of clomipramine on depression-like behaviors induced by the chronic social defeat paradigm in tree shrews.
    Journal of psychopharmacology (Oxford, England), 2018, Volume: 32, Issue:10

    Topics: Anhedonia; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Interpersonal Relations; Male; Motivation; Reward; Social Behavior; Tupaiidae

2018
Back-translating behavioral intervention for autism spectrum disorders to mice with blunted reward restores social abilities.
    Translational psychiatry, 2018, 09-21, Volume: 8, Issue:1

    Topics: Animals; Applied Behavior Analysis; Autism Spectrum Disorder; Behavior Therapy; Behavior, Animal; Disease Models, Animal; Female; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Receptors, Opioid, mu; Reward; Social Behavior

2018
Impulsive choice does not predict binge-like eating in rats.
    Behavioural pharmacology, 2018, Volume: 29, Issue:8

    Topics: Animals; Binge-Eating Disorder; Choice Behavior; Conditioning, Operant; Delay Discounting; Disease Models, Animal; Feeding Behavior; Impulsive Behavior; Male; Predictive Value of Tests; Rats; Rats, Wistar; Reward; Satiety Response

2018
Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 11-06, Volume: 115, Issue:45

    Topics: Animals; Catheters, Indwelling; Cocaine-Related Disorders; Conditioning, Psychological; Coumarins; Disease Models, Animal; Gene Expression Regulation; Humans; Injections, Intravenous; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Narcotic Antagonists; Neurons; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Reward; Self Administration; Signal Transduction; Substance Abuse, Intravenous; Toxicity Tests, Acute; Toxicity Tests, Chronic

2018
Intermittent intake of rapid cocaine injections promotes the risk of relapse and increases mesocorticolimbic BDNF levels during abstinence.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:6

    Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Craving; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Nucleus Accumbens; Prefrontal Cortex; Rats; Reward; Self Administration; Time Factors; Ventral Tegmental Area

2019
Cocaine and cocaine expectancy increase growth hormone, ghrelin, GLP-1, IGF-1, adiponectin, and corticosterone while decreasing leptin, insulin, GIP, and prolactin.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 176

    Topics: Adiponectin; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Drug Substitution; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon-Like Peptide 1; Growth Hormone; Injections, Intravenous; Insulin; Leptin; Prolactin; Rats; Reward; Saline Solution; Self Administration; Signal Transduction

2019
Oxytocin prevents the increase of cocaine-related responses produced by social defeat.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Classical; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Hippocampus; Male; Mice; Oxytocin; Prefrontal Cortex; Reinforcement, Psychology; Reward; Self Administration; Stress, Psychological

2019
Fractionating Blunted Reward Processing Characteristic of Anhedonia by Over-Activating Primate Subgenual Anterior Cingulate Cortex.
    Neuron, 2019, 01-16, Volume: 101, Issue:2

    Topics: Anhedonia; Animals; Blood Pressure; Callithrix; Citalopram; Conditioning, Classical; Discrimination, Psychological; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Fluorodeoxyglucose F18; Food Preferences; Gyrus Cinguli; Humans; Ketamine; Locomotion; Male; Proto-Oncogene Proteins c-fos; Reward; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Sucrose

2019
High-fat diet accelerates extreme obesity with hyperphagia in female heterozygous Mecp2-null mice.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Animals; Appetite; Diet, High-Fat; Disease Models, Animal; Dopamine; Feeding Behavior; Female; Heterozygote; Humans; Hyperphagia; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Rett Syndrome; Reward; Severity of Illness Index; Time Factors; Ventral Tegmental Area

2019
Translating a rodent measure of negative bias into humans: the impact of induced anxiety and unmedicated mood and anxiety disorders.
    Psychological medicine, 2020, Volume: 50, Issue:2

    Topics: Adolescent; Adult; Affect; Animals; Anxiety Disorders; Bias; Disease Models, Animal; Female; Humans; Male; Mood Disorders; Reaction Time; Reward; Rodentia; Translational Research, Biomedical; Young Adult

2020
Cannabinoid and nicotine exposure during adolescence induces sex-specific effects on anxiety- and reward-related behaviors during adulthood.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Animals; Anxiety; Benzoxazines; Conditioning, Operant; Disease Models, Animal; Female; Humans; Locomotion; Male; Mice; Morpholines; Naphthalenes; Nicotine; Reward; Sex Characteristics; Sucrose

2019
Motivational Impairment is Accompanied by Corticoaccumbal Dysfunction in the BACHD-Tg5 Rat Model of Huntington's Disease.
    Cerebral cortex (New York, N.Y. : 1991), 2019, 12-17, Volume: 29, Issue:11

    Topics: Animals; Disease Models, Animal; Huntingtin Protein; Huntington Disease; Male; Motivation; Neural Pathways; Neurons; Nucleus Accumbens; Optogenetics; Prefrontal Cortex; Rats, Transgenic; Reward

2019
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: Analgesics, Opioid; Animals; Brain; Conditioning, Psychological; Disease Models, Animal; Heroin; Locomotion; Male; Mice; Mice, Inbred C57BL; Morphine Derivatives; Opioid-Related Disorders; Reward

2020
Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degener
    Experimental neurology, 2019, Volume: 317

    Topics: Animals; Axons; Choice Behavior; Corpus Callosum; Disease Models, Animal; Dopaminergic Neurons; Gliosis; Head Injuries, Closed; Inflammation; Male; Neurodegenerative Diseases; Olfactory Tubercle; Phosphorylation; Rats; Rats, Long-Evans; Reward; tau Proteins; Tauopathies; White Matter

2019
Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice.
    Behavioural brain research, 2019, 07-23, Volume: 367

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Cytokines; Disease Models, Animal; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Fathers; Female; Gene Expression Regulation; Inheritance Patterns; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Sequence Analysis, RNA; Sex Characteristics

2019
Protective and therapeutic benefits of environmental enrichment on binge-like sucrose intake in C57BL/6J mice.
    Appetite, 2019, 07-01, Volume: 138

    Topics: Animals; Behavior, Animal; Binge-Eating Disorder; Disease Models, Animal; Environment; Male; Mice; Mice, Inbred C57BL; Play and Playthings; Reward; Sucrose

2019
DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self-administration in rats.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Male; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Self Administration

2020
Can Slot-Machine Reward Schedules Induce Gambling Addiction in Rats?
    Journal of gambling studies, 2019, Volume: 35, Issue:3

    Topics: Animals; Behavior, Addictive; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Gambling; Motivation; Rats; Rats, Wistar; Reinforcement Schedule; Reward

2019
Neuronal HMGB1 in nucleus accumbens regulates cocaine reward memory.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; HMGB1 Protein; Male; Memory; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward

2020
In a Model of Neuroinflammation Designed to Mimic Delirium, Quetiapine Reduces Cortisol Secretion and Preserves Reversal Learning in the Attentional Set Shifting Task.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2019, Volume: 14, Issue:3

    Topics: Animals; Antipsychotic Agents; Appetitive Behavior; Attention; Delirium; Disease Models, Animal; Drug Evaluation, Preclinical; Executive Function; Female; Frontal Lobe; Hydrocortisone; Inflammation; Lipopolysaccharides; Quetiapine Fumarate; Random Allocation; Rats; Rats, Sprague-Dawley; Reversal Learning; Reward; Set, Psychology; Tumor Necrosis Factor-alpha

2019
Effects of haloperidol on cognitive function and behavioural flexibility in the IntelliCage social home cage environment.
    Behavioural brain research, 2019, 10-03, Volume: 371

    Topics: Animals; Behavior, Animal; Cognition; Discrimination Learning; Disease Models, Animal; Exploratory Behavior; Female; Haloperidol; Mice; Mice, Inbred C57BL; Motor Activity; Reversal Learning; Reward; Schizophrenia; Social Environment

2019
Assessing Reality Testing in Mice Through Dopamine-Dependent Associatively Evoked Processing of Absent Gustatory Stimuli.
    Schizophrenia bulletin, 2020, 01-04, Volume: 46, Issue:1

    Topics: Animals; Antipsychotic Agents; Association Learning; Auditory Perception; Behavior, Animal; Cerebral Cortex; Conditioning, Classical; Delusions; Disease Models, Animal; Dopamine; Hallucinations; Haloperidol; Mice; Mice, Transgenic; Nerve Tissue Proteins; Reality Testing; Reward; Social Isolation; Taste Perception

2020
Incisional Injury Modulates Morphine Reward and Morphine-Primed Reinstatement: A Role of Kappa Opioid Receptor Activation.
    Anesthesia and analgesia, 2020, Volume: 130, Issue:1

    Topics: Acute Pain; Animals; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Enkephalins; Extinction, Psychological; Male; Mice, Inbred C57BL; Morphine; Narcotic Antagonists; Pain Threshold; Protein Precursors; Receptors, Opioid, kappa; Reward; Signal Transduction; Wounds, Penetrating

2020
Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 06-25, Volume: 116, Issue:26

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Cadherins; Carrier Proteins; Case-Control Studies; Disease Models, Animal; Exome Sequencing; Exploratory Behavior; Female; Finland; Genetic Predisposition to Disease; Genotyping Techniques; Humans; Locomotion; Male; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Rats; Reward; Substance-Related Disorders

2019
Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding.
    Science (New York, N.Y.), 2019, 06-28, Volume: 364, Issue:6447

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Glutamic Acid; Hypothalamic Area, Lateral; Mice; Neurons; Obesity; Reward; Transcriptome; Vesicular Glutamate Transport Protein 2

2019
Experimental Traumatic Brain Injury during Adolescence Enhances Cocaine Rewarding Efficacy and Dysregulates Dopamine and Neuroimmune Systems in Brain Reward Substrates.
    Journal of neurotrauma, 2020, 01-01, Volume: 37, Issue:1

    Topics: Age Factors; Animals; Brain; Brain Injuries, Traumatic; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred C57BL; Neuroimmunomodulation; Reward

2020
Chronic wheel running reduces maladaptive patterns of methamphetamine intake: regulation by attenuation of methamphetamine-induced neuronal nitric oxide synthase.
    Brain structure & function, 2014, Volume: 219, Issue:2

    Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Caspase 3; Cell Proliferation; Central Nervous System Stimulants; Disease Models, Animal; Hippocampus; Ki-67 Antigen; Male; Methamphetamine; Neural Stem Cells; Neurons; Neurotoxicity Syndromes; Nitric Oxide Synthase; Oncogene Proteins v-fos; Rats; Rats, Wistar; Reward; Running; Self Administration; Time Factors

2014
Is alcoholism learned? Insights from the fruit fly.
    Current opinion in neurobiology, 2013, Volume: 23, Issue:4

    Topics: Alcoholism; Animals; Brain; Central Nervous System Depressants; Disease Models, Animal; Drosophila; Ethanol; Humans; Learning; Reward

2013
Levodopa gains psychostimulant-like properties after nigral dopaminergic loss.
    Annals of neurology, 2013, Volume: 74, Issue:1

    Topics: Adenoviridae; alpha-Synuclein; Animals; Antiparkinson Agents; Conditioning, Operant; Disease Models, Animal; Dopaminergic Neurons; Food Preferences; Humans; Levodopa; Male; Mutation; Parkinson Disease; Rats; Rats, Wistar; Reward; Saccharin; Substantia Nigra; Sweetening Agents; Taste; Transduction, Genetic; Tyrosine 3-Monooxygenase; Ubiquitin

2013
A translational rodent assay of affective biases in depression and antidepressant therapy.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:9

    Topics: Affect; Animals; Antidepressive Agents; Appetite Depressants; Cannabinoid Receptor Antagonists; Carbolines; Depression; Discrimination Learning; Disease Models, Animal; Environment; Isotretinoin; Male; Piperidines; Pyrazoles; Rats; Reward; Rimonabant; Stress, Psychological; Translational Research, Biomedical

2013
Lesions of the dorsomedial striatum impair formation of attentional set in rats.
    Neuropharmacology, 2013, Volume: 71

    Topics: Animals; Attention; Behavior, Animal; Corpus Striatum; Discrimination Learning; Disease Models, Animal; Female; Learning; Learning Disabilities; Neurons; Quinolinic Acid; Rats; Rats, Inbred Strains; Reward

2013
Chronic scopolamine-injection-induced cognitive deficit on reward-directed instrumental learning in rat is associated with CREB signaling activity in the cerebral cortex and dorsal hippocampus.
    Psychopharmacology, 2013, Volume: 230, Issue:2

    Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cognition Disorders; Conditioning, Operant; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hippocampus; Male; Memory; Muscarinic Antagonists; Phosphorylation; Rats; Rats, Wistar; Reward; Scopolamine; Signal Transduction

2013
Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal.
    Brain structure & function, 2014, Volume: 219, Issue:5

    Topics: Action Potentials; Analgesics, Opioid; Animals; Apomorphine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopaminergic Neurons; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Signal Transduction; Substance Withdrawal Syndrome; Time Factors; Ventral Tegmental Area

2014
Differential impact of a complex environment on positive affect in an animal model of individual differences in emotionality.
    Neuroscience, 2013, Sep-17, Volume: 248

    Topics: Affect; Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Environment; Exploratory Behavior; Genes, fos; Individuality; Locomotion; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger; Stress, Psychological; Ultrasonics

2013
The histidine triad nucleotide binding 1 protein is involved in nicotine reward and physical nicotine withdrawal in mice.
    Neuroscience letters, 2013, Aug-29, Volume: 550

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Nicotine; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder

2013
A choice-based screening method for compulsive drug users in rats.
    Current protocols in neuroscience, 2013, Volume: Chapter 9

    Topics: Animals; Choice Behavior; Cocaine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug-Seeking Behavior; Rats; Rats, Wistar; Reward; Saccharin; Self Administration; Substance Abuse Detection; Sweetening Agents; Time Factors

2013
Why am I lost without dopamine? Effects of 6-OHDA lesion on the encoding of reward and decision process in CA3.
    Neurobiology of disease, 2013, Volume: 59

    Topics: Action Potentials; Adrenergic Agents; Animals; Brain Injuries; CA3 Region, Hippocampal; Decision Making; Disease Models, Animal; Dopamine; Exploratory Behavior; Food Deprivation; Functional Laterality; Male; Maze Learning; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Reward

2013
Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:5

    Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Male; Metabolic Networks and Pathways; Metabolome; Methamphetamine; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders

2014
Assessment of reward responsiveness in the response bias probabilistic reward task in rats: implications for cross-species translational research.
    Translational psychiatry, 2013, Aug-27, Volume: 3

    Topics: Amphetamine; Animals; Benzothiazoles; Conditioning, Operant; Discrimination Learning; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Mood Disorders; Pramipexole; Rats; Rats, Long-Evans; Rats, Wistar; Reinforcement, Psychology; Reward; Translational Research, Biomedical

2013
Adolescent social defeat decreases spatial working memory performance in adulthood.
    Behavioral and brain functions : BBF, 2013, Oct-17, Volume: 9

    Topics: Age Factors; Animals; Conditioning, Psychological; Disease Models, Animal; Dominance-Subordination; Dopamine; Maze Learning; Memory, Short-Term; Mesencephalon; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Sexual Maturation; Social Behavior; Space Perception; Stress, Psychological

2013
Changes in sensitivity of reward and motor behavior to dopaminergic, glutamatergic, and cholinergic drugs in a mouse model of fragile X syndrome.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Blotting, Western; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; Fragile X Syndrome; Immunoenzyme Techniques; Male; Mice; Mice, Knockout; Motor Activity; Muscarinic Antagonists; Piperazines; Pyridines; Quinolones; Receptor, Metabotropic Glutamate 5; Reward; Trihexyphenidyl; Tyrosine 3-Monooxygenase

2013
An automated maze task for assessing hippocampus-sensitive memory in mice.
    Behavioural brain research, 2014, Mar-15, Volume: 261

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Electronic Data Processing; Excitatory Amino Acid Agonists; Hippocampus; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; N-Methylaspartate; Reaction Time; Reward

2014
Blockade of hypocretin receptor-1 preferentially prevents cocaine seeking: comparison with natural reward seeking.
    Neuroreport, 2014, May-07, Volume: 25, Issue:7

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Reward; Self Administration; Sweetening Agents; Urea

2014
Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward.
    Nature neuroscience, 2014, Volume: 17, Issue:2

    Topics: Analysis of Variance; Animals; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine; Enkephalins; Exploratory Behavior; Flow Cytometry; Green Fluorescent Proteins; Mice; Mice, Transgenic; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neural Pathways; Neurons; Pain; Pain Measurement; Protein Precursors; Receptors, Opioid, mu; Reward; Substance Withdrawal Syndrome

2014
Random-ratio schedules produce greater demand for i.v. drug administration than fixed-ratio schedules in rhesus monkeys.
    Psychopharmacology, 2014, Volume: 231, Issue:15

    Topics: Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Ketamine; Macaca mulatta; Male; Motivation; Piperidines; Reinforcement Schedule; Remifentanil; Reward; Self Administration; Substance-Related Disorders

2014
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking.
    Nature neuroscience, 2014, Volume: 17, Issue:4

    Topics: Animals; Basal Ganglia; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopaminergic Neurons; Male; Neural Inhibition; Neural Pathways; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine; Recurrence; Reward; Ventral Tegmental Area

2014
The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression.
    Behavioural brain research, 2014, Jun-01, Volume: 266

    Topics: Acetylcysteine; Animals; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Free Radical Scavengers; Male; Motor Activity; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration

2014
Dissociable effects of basolateral amygdala lesions on decision making biases in rats when loss or gain is emphasized.
    Cognitive, affective & behavioral neuroscience, 2014, Volume: 14, Issue:4

    Topics: Analysis of Variance; Animals; Basolateral Nuclear Complex; Bias; Brain Injuries; Conditioning, Operant; Decision Making; Disease Models, Animal; Exploratory Behavior; Quinolinic Acid; Rats; Rats, Long-Evans; Reaction Time; Reward; Risk-Taking

2014
Persistent pain facilitates response to morphine reward by downregulation of central amygdala GABAergic function.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:9

    Topics: Analgesics, Opioid; Animals; Central Amygdaloid Nucleus; Chronic Pain; Conditioning, Psychological; Disease Models, Animal; Down-Regulation; Freund's Adjuvant; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Membrane Glycoproteins; Morphine; Neurons; Random Allocation; Rats, Wistar; Receptors, GABA-A; Receptors, Interleukin-1; Reward; Space Perception; Synaptic Transmission

2014
Tobacco particulate matter self-administration in rats: differential effects of tobacco type.
    Addiction biology, 2015, Volume: 20, Issue:2

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Drug-Seeking Behavior; Male; Motivation; Nicotiana; Nicotine; Nicotinic Agonists; Particulate Matter; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder

2015
Effects of dopamine D1 receptor blockade in the prelimbic prefrontal cortex or lateral dorsal striatum on frontostriatal function in Wistar and Spontaneously Hypertensive Rats.
    Behavioural brain research, 2014, Jul-15, Volume: 268

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Benzazepines; Cognition; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Executive Function; Male; Motor Activity; Neuropsychological Tests; Prefrontal Cortex; Rats, Inbred SHR; Rats, Wistar; Receptors, Dopamine D1; Reward; Species Specificity; Task Performance and Analysis

2014
Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice.
    Neuropharmacology, 2014, Volume: 85

    Topics: Animals; Anxiety; Aryl Hydrocarbon Hydroxylases; Conditioning, Psychological; Cytochrome P450 Family 2; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Male; Mecamylamine; Methoxsalen; Mice, Inbred ICR; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Reward; Severity of Illness Index; Substance Withdrawal Syndrome; Tobacco Use Disorder

2014
Zebrafish and conditioned place preference: a translational model of drug reward.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Dec-03, Volume: 55

    Topics: Analysis of Variance; Animals; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Reward; Space Perception; Spatial Behavior; Substance-Related Disorders; Zebrafish

2014
Lipopolysaccharide reduces incentive motivation while boosting preference for high reward in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:12

    Topics: Animals; Choice Behavior; Disease Models, Animal; Food; Inflammation; Lipopolysaccharides; Male; Mice, Inbred C57BL; Motivation; Motor Activity; Neuropsychological Tests; Reinforcement Schedule; Reward

2014
Unilateral olfactory deficit in a hemiparkinson's disease mouse model.
    Neuroreport, 2014, Aug-20, Volume: 25, Issue:12

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Discrimination, Psychological; Disease Models, Animal; Functional Laterality; Immunohistochemistry; Male; Maze Learning; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Neuropsychological Tests; Olfactory Perception; Oxidopamine; Parkinsonian Disorders; Reward

2014
A leptin-mediated central mechanism in analgesia-enhanced opioid reward in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Jul-16, Volume: 34, Issue:29

    Topics: Analgesics, Opioid; Animals; Animals, Newborn; Arthritis, Experimental; Astrocytes; Cerebral Cortex; Conditioning, Operant; Disease Models, Animal; Gene Expression Regulation; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Morphine; Mutation; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reward

2014
Involvement of sigma 1 receptor in the SSRI-induced suppression of the methamphetamine-induced behavioral sensitization and rewarding effects in mice.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2013, Volume: 33, Issue:2

    Topics: Animals; Anisoles; Behavior, Animal; Disease Models, Animal; Fluvoxamine; Methamphetamine; Mice; Propylamines; Rats; Receptors, sigma; Reward; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor

2013
Cannabinoids reward sensitivity in a neurodevelopmental animal model of schizophrenia: a brain stimulation reward study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:9

    Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Benzoxazines; Brain; Brain Injuries; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Dronabinol; Female; Hippocampus; Male; Morpholines; Motivation; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reward; Schizophrenia; Self Administration; Time Factors

2014
Rewarding brain stimulation reverses the disruptive effect of amygdala damage on emotional learning.
    Behavioural brain research, 2014, Nov-01, Volume: 274

    Topics: Acetylcholinesterase; Amygdala; Analysis of Variance; Animals; Avoidance Learning; Brain Injuries; Deep Brain Stimulation; Disease Models, Animal; Electrolysis; Male; Memory Disorders; Rats; Rats, Wistar; Reward; Self Administration

2014
Okadaic acid blocks the effects of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats.
    Neuropharmacology, 2014, Volume: 86

    Topics: Animals; Azacitidine; CA1 Region, Hippocampal; Cerebral Cortex; Conditioning, Psychological; Decitabine; Disease Models, Animal; DNA Modification Methylases; Enzyme Inhibitors; Male; Memory; Morphine; Morphine Dependence; Narcotics; Okadaic Acid; Rats, Sprague-Dawley; Reward; Spatial Behavior

2014
Modelling Alzheimer-like cognitive deficits in rats using biperiden as putative cognition impairer.
    Behavioural brain research, 2014, Nov-01, Volume: 274

    Topics: Animals; Biperiden; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Memory, Short-Term; Muscarinic Antagonists; Rats; Reaction Time; Reward

2014
Knockdown of CRF1 receptors in the ventral tegmental area attenuates cue- and acute food deprivation stress-induced cocaine seeking in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Aug-27, Volume: 34, Issue:35

    Topics: Animals; Behavior, Animal; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Food Deprivation; Gene Knockdown Techniques; Male; Mice; Mice, Inbred C57BL; Receptors, Corticotropin-Releasing Hormone; Reverse Transcriptase Polymerase Chain Reaction; Reward; Stress, Psychological; Ventral Tegmental Area

2014
Sexual performance and precontact 50-kHz ultrasonic vocalizations in WAG/Rij rats: effects of opioid receptor treatment.
    Epilepsy & behavior : E&B, 2014, Volume: 39

    Topics: Animals; Disease Models, Animal; Epilepsy, Absence; Female; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid; Reward; Sexual Behavior, Animal; Vocalization, Animal

2014
The antipsychotic aripiprazole selectively prevents the stimulant and rewarding effects of morphine in mice.
    European journal of pharmacology, 2014, Nov-05, Volume: 742

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Central Nervous System Stimulants; Conditioning, Psychological; Disease Models, Animal; Male; Mice; Morphine; Motor Activity; Nociception; Opioid-Related Disorders; Piperazines; Quinolones; Reward

2014
Expression and localization of cannabinoid receptor 1 in rats' brain treated with acute and repeated morphine.
    Acta neurobiologiae experimentalis, 2014, Volume: 74, Issue:3

    Topics: Analgesics, Opioid; Animals; Brain; Cannabinoids; Cells, Cultured; Disease Models, Animal; Humans; Male; Morphine; Rats, Wistar; Receptor, Cannabinoid, CB1; Reward

2014
High-anxiety rats are less sensitive to the rewarding affects of amphetamine on 50kHz USV.
    Behavioural brain research, 2014, Dec-15, Volume: 275

    Topics: Amphetamine; Analysis of Variance; Animals; Anxiety; Central Nervous System Stimulants; Conditioning, Psychological; Disease Models, Animal; Dopamine; Fear; Homovanillic Acid; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Wistar; Reward; Vocalization, Animal

2014
Anti-anxiety self-medication in rats: oral consumption of chlordiazepoxide and ethanol after reward devaluation.
    Behavioural brain research, 2015, Feb-01, Volume: 278

    Topics: Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Conditioning, Operant; Disease Models, Animal; Ethanol; Feeding Behavior; Food Deprivation; Food Preferences; Male; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration; Self Medication; Sucrose

2015
Validation of operant social motivation paradigms using BTBR T+tf/J and C57BL/6J inbred mouse strains.
    Brain and behavior, 2014, Volume: 4, Issue:5

    Topics: Animals; Autistic Disorder; Disease Models, Animal; Feasibility Studies; Food; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motivation; Reward; Social Behavior

2014
Prenatal malnutrition leads to deficits in attentional set shifting and decreases metabolic activity in prefrontal subregions that control executive function.
    Developmental neuroscience, 2014, Volume: 36, Issue:6

    Topics: Animals; Attention; Cerebral Cortex; Cognition Disorders; Deoxyglucose; Disease Models, Animal; Executive Function; Female; Fetal Nutrition Disorders; Male; Prefrontal Cortex; Pregnancy; Rats; Rats, Long-Evans; Reward

2014
Chronic unpredictable stress during adolescence causes long-term anxiety.
    Behavioural brain research, 2015, Feb-01, Volume: 278

    Topics: Adrenal Cortex Hormones; Age Factors; Animals; Anxiety; Cognition; Disease Models, Animal; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Stress, Psychological

2015
Cocaine-induced suppression of saccharin intake and morphine modulation of Ca²⁺ channel currents in sensory neurons of OPRM1 A118G mice.
    Physiology & behavior, 2015, Volume: 139

    Topics: Animals; Behavior, Addictive; Calcium Channels; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Humans; Male; Mice, Transgenic; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Reward; Saccharin; Sensory Receptor Cells; Substance Withdrawal Syndrome; Trigeminal Ganglion

2015
Pharmacological inactivation of the prelimbic cortex emulates compulsive reward seeking in rats.
    Brain research, 2015, Dec-02, Volume: 1628, Issue:Pt A

    Topics: Animals; Baclofen; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Decision Making; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Executive Function; GABA Agonists; Goals; Impulsive Behavior; Male; Muscimol; Rats, Wistar; Reward

2015
Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats.
    The international journal of neuropsychopharmacology, 2014, Oct-31, Volume: 18, Issue:4

    Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Dietary Sucrose; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Female; Male; Methylphenidate; Motivation; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Wistar; Reward

2014
Persistent palatable food preference in rats with a history of limited and extended access to methamphetamine self-administration.
    Addiction biology, 2015, Volume: 20, Issue:5

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Food Preferences; Male; Methamphetamine; Rats; Rats, Sprague-Dawley; Reward; Self Administration

2015
Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice.
    Current HIV research, 2015, Volume: 13, Issue:1

    Topics: Animals; Anti-HIV Agents; Chemokines; Cocaine; Cytokines; Disease Models, Animal; Dopamine Uptake Inhibitors; Heterocyclic Compounds, 4 or More Rings; HIV Infections; HIV-1; Inflammation; Isoquinolines; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurocognitive Disorders; Reward; tat Gene Products, Human Immunodeficiency Virus

2015
Signal attenuation as a rat model of obsessive compulsive disorder.
    Journal of visualized experiments : JoVE, 2015, Jan-09, Issue:95

    Topics: Animals; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Male; Obsessive-Compulsive Disorder; Rats; Reward

2015
Alterations of reward mechanisms in bulbectomised rats.
    Behavioural brain research, 2015, Jun-01, Volume: 286

    Topics: Alcohol Drinking; Animals; Body Temperature; Central Nervous System Depressants; Conditioning, Psychological; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Water; Ethanol; Male; Motor Activity; Olfactory Bulb; Rats, Wistar; Reward; Self Administration; Spatial Learning

2015
Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Apr-15, Volume: 35, Issue:15

    Topics: Alcohol Drinking; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Depressants; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Ethanol; Glutamate Decarboxylase; Male; Nicotine; Nicotinic Agonists; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-fos; Quinine; Rats; Rats, Wistar; Reward; Self Administration; Time Factors

2015
Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G Polymorphism.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:11

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Male; Mice, Transgenic; Motor Activity; Narcotic Antagonists; Nucleus Accumbens; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Reward; Self Stimulation; Tissue Culture Techniques; Ventral Tegmental Area

2015
Sex differences in motivational responses to dietary fat in Syrian hamsters.
    Physiology & behavior, 2015, Aug-01, Volume: 147

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety; Calorimetry; Cohort Studies; Cricetinae; Cyclic AMP Response Element-Binding Protein; Desipramine; Dietary Fats; Disease Models, Animal; Exploratory Behavior; Female; Fluoxetine; Gene Expression Regulation; Male; Mesocricetus; Motivation; Reward; RNA, Messenger; Sex Characteristics; Social Behavior; Social Isolation

2015
Altered basolateral amygdala encoding in an animal model of schizophrenia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Apr-22, Volume: 35, Issue:16

    Topics: Action Potentials; Animals; Animals, Newborn; Basolateral Nuclear Complex; Cues; Disease Models, Animal; Hippocampus; Male; Neurons; Olfactory Perception; Orientation; Rats; Reward; Schizophrenia; Schizophrenic Psychology

2015
Persistent neuropathic pain influences persistence behavior in rats.
    Journal of oral & facial pain and headache, 2015,Spring, Volume: 29, Issue:2

    Topics: Animals; Behavior, Animal; Conditioning, Psychological; Cues; Disease Models, Animal; Facial Pain; Fatigue; Hyperesthesia; Learning; Male; Neuralgia; Orbit; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Reward; Touch; Vibrissae

2015
Voluntary Alcohol Intake following Blast Exposure in a Rat Model of Mild Traumatic Brain Injury.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Animals; Brain Injuries; Choice Behavior; Disease Models, Animal; Drinking; Ethanol; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders

2015
The impact of motivation on cognitive performance in an animal model of the negative and cognitive symptoms of schizophrenia.
    Behavioral neuroscience, 2015, Volume: 129, Issue:3

    Topics: Animals; Attention; Cognition; Cohort Studies; Conditioning, Operant; Corpus Striatum; Discrimination, Psychological; Disease Models, Animal; Male; Memory, Short-Term; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Motivation; Neurons; Neuropsychological Tests; Receptors, Dopamine D2; Reward; Schizophrenia; Schizophrenic Psychology

2015
Neuropeptide Y system in accumbens shell mediates ethanol self-administration in posterior ventral tegmental area.
    Addiction biology, 2016, Volume: 21, Issue:4

    Topics: Animals; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Male; Neuropeptide Y; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Ventral Tegmental Area

2016
Paternal alcohol exposure in mice alters brain NGF and BDNF and increases ethanol-elicited preference in male offspring.
    Addiction biology, 2016, Volume: 21, Issue:4

    Topics: Alcoholism; Animals; Blotting, Western; Brain; Brain-Derived Neurotrophic Factor; Central Nervous System Depressants; Chromatography, Gas; Disease Models, Animal; Ethanol; Fathers; Male; Mice; Nerve Growth Factor; Reward; Sucrose

2016
Repeated social defeat stress enhances the anxiogenic effect of bright light on operant reward-seeking behavior in rats.
    Behavioural brain research, 2015, Sep-01, Volume: 290

    Topics: Anhedonia; Animals; Anxiety; Appetitive Behavior; Disease Models, Animal; Dominance-Subordination; Light; Male; Rats; Rats, Sprague-Dawley; Reward; Stress, Psychological

2015
MAM (E17) rodent developmental model of neuropsychiatric disease: disruptions in learning and dysregulation of nucleus accumbens dopamine release, but spared executive function.
    Psychopharmacology, 2015, Volume: 232, Issue:21-22

    Topics: Amphetamine; Animals; Conditioning, Classical; Disease Models, Animal; Dopamine; Executive Function; Learning; Male; Methylazoxymethanol Acetate; Motivation; Nucleus Accumbens; Rats, Sprague-Dawley; Reward; Schizophrenia; Schizophrenic Psychology

2015
Adolescent Alcohol Exposure Amplifies the Incentive Value of Reward-Predictive Cues Through Potentiation of Phasic Dopamine Signaling.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:13

    Topics: Animals; Anticipation, Psychological; Central Nervous System Depressants; Conditioning, Classical; Cues; Disease Models, Animal; Dopamine; Electrodes, Implanted; Ethanol; Extinction, Psychological; Male; Nucleus Accumbens; Rats, Sprague-Dawley; Reward; Underage Drinking

2015
Extinction of alcohol seeking is enhanced by compound extinction and the noradrenaline reuptake inhibitor atomoxetine.
    Addiction biology, 2017, Volume: 22, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Alcoholism; Animals; Atomoxetine Hydrochloride; Behavior, Animal; Conditioning, Classical; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Rats, Wistar; Reward

2017
Differential expression of CART in feeding and reward circuits in binge eating rat model.
    Behavioural brain research, 2015, Sep-15, Volume: 291

    Topics: Anhedonia; Animals; Binge-Eating Disorder; Brain; Cannabinoid Receptor Antagonists; Disease Models, Animal; Eating; Male; Nerve Tissue Proteins; Neural Pathways; Piperidines; Pyrazoles; Random Allocation; Rats, Wistar; Reward; Rimonabant; Satiation; Synaptophysin

2015
The Female Encounter Test: A Novel Method for Evaluating Reward-Seeking Behavior or Motivation in Mice.
    The international journal of neuropsychopharmacology, 2015, May-29, Volume: 18, Issue:11

    Topics: Amino Acids; Animals; Antidepressive Agents, Second-Generation; Castration; Choice Behavior; Corticosterone; Depressive Disorder; Disease Models, Animal; Equipment Design; Estrous Cycle; Excitatory Amino Acid Antagonists; Female; Fluvoxamine; Lipopolysaccharides; Male; Mice; Motivation; Nucleus Accumbens; Psychological Tests; Reward; Social Behavior; Social Isolation; Xanthenes

2015
Microglia disrupt mesolimbic reward circuitry in chronic pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jun-03, Volume: 35, Issue:22

    Topics: Animals; Area Under Curve; Chronic Pain; Cocaine; Conditioning, Classical; Disease Models, Animal; Glutamate Decarboxylase; Hyperalgesia; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Minocycline; Morphine; Nerve Net; Nucleus Accumbens; Pain Threshold; Rats; Rats, Sprague-Dawley; Reward; Sciatic Neuropathy; Ventral Tegmental Area

2015
Anhedonia, Reduced Cocaine Reward, and Dopamine Dysfunction in a Rat Model of Posttraumatic Stress Disorder.
    Biological psychiatry, 2015, Dec-15, Volume: 78, Issue:12

    Topics: Anhedonia; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration; Stress Disorders, Post-Traumatic

2015
Cigarette smoke exposure during adolescence enhances sensitivity to the rewarding effects of nicotine in adulthood, even after a long period of abstinence.
    Neuropharmacology, 2015, Volume: 99

    Topics: Aging; Animals; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Motivation; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Reward; Self Administration; Spatial Behavior; Tobacco Smoke Pollution; Tobacco Use Disorder

2015
Enhanced flavor-nutrient conditioning in obese rats on a high-fat, high-carbohydrate choice diet.
    Physiology & behavior, 2015, Nov-01, Volume: 151

    Topics: Animal Feed; Animals; Choice Behavior; Conditioning, Psychological; Diet, High-Fat; Dietary Fats; Disease Models, Animal; Drinking Water; Female; Flavoring Agents; Food Preferences; Glucose; Motor Activity; Obesity; Polysaccharides; Random Allocation; Rats, Sprague-Dawley; Reward; Saccharin

2015
Modulation of cue-induced firing of ventral tegmental area dopamine neurons by leptin and ghrelin.
    International journal of obesity (2005), 2015, Volume: 39, Issue:12

    Topics: Animals; Appetite; Cues; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Feeding Behavior; Ghrelin; Leptin; Male; Obesity; Overnutrition; Rats; Rats, Wistar; Reward; Signal Transduction; Ventral Tegmental Area

2015
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats.
    Neuropharmacology, 2015, Volume: 99

    Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological

2015
Lesions of the paraventricular nucleus of the thalamus differentially affect sign- and goal-tracking conditioned responses.
    The European journal of neuroscience, 2015, Volume: 42, Issue:7

    Topics: Animals; Behavior, Animal; Conditioning, Classical; Cues; Disease Models, Animal; Male; Motivation; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reward

2015
Procedural Performance Benefits after Excitotoxic Hippocampal Lesions in the Rat Sequential Reaction Time Task.
    Neurotoxicity research, 2016, Volume: 29, Issue:1

    Topics: Analysis of Variance; Animals; Brain Injuries; Conditioning, Operant; Disease Models, Animal; Excitatory Amino Acid Agonists; Extinction, Psychological; Hippocampus; Ibotenic Acid; Male; Rats; Rats, Wistar; Reaction Time; Recognition, Psychology; Reward

2016
Brain disease model of addiction: why is it so controversial?
    The lancet. Psychiatry, 2015, Volume: 2, Issue:8

    Topics: Behavior, Addictive; Brain; Brain Diseases; Disease Models, Animal; Dopamine; Humans; Obesity; Reward; Substance-Related Disorders

2015
Optimizing Deep Brain Stimulation of the Nucleus Accumbens in a Reward Preference Rat Model.
    Neuromodulation : journal of the International Neuromodulation Society, 2015, Volume: 18, Issue:7

    Topics: Animals; Biophysics; Conditioning, Operant; Deep Brain Stimulation; Disease Models, Animal; Disruptive, Impulse Control, and Conduct Disorders; Functional Laterality; Male; Nucleus Accumbens; Psychomotor Performance; Rats; Rats, Long-Evans; Reward; Self Stimulation

2015
Cocaine-induced reward enhancement measured with intracranial self-stimulation in rats bred for low versus high saccharin intake.
    Behavioural pharmacology, 2016, Volume: 27, Issue:2-3 Spec I

    Topics: Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Food Preferences; Male; Rats; Reward; Saccharin; Self Stimulation; Substance-Related Disorders; Sweetening Agents

2016
The glucagon-like peptide 1 receptor agonist liraglutide attenuates the reinforcing properties of alcohol in rodents.
    Addiction biology, 2016, Volume: 21, Issue:2

    Topics: Alcoholism; Animals; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Dopamine; Ethanol; Hypoglycemic Agents; Liraglutide; Mice; Microdialysis; Nucleus Accumbens; Prostheses and Implants; Rats; Reinforcement, Psychology; Reward; Self Administration

2016
A mobile, high-throughput semi-automated system for testing cognition in large non-primate animal models of Huntington disease.
    Journal of neuroscience methods, 2016, 05-30, Volume: 265

    Topics: Acoustic Stimulation; Animals; Automation, Laboratory; Cognition; Conditioning, Operant; Discrimination, Psychological; Disease Models, Animal; Equipment Design; Female; Food; Habituation, Psychophysiologic; Huntington Disease; Male; Photic Stimulation; Psychological Tests; Reversal Learning; Reward; Sheep, Domestic; Visual Perception

2016
Abnormal context-reward associations in an immune-mediated neurodevelopmental mouse model with relevance to schizophrenia.
    Translational psychiatry, 2015, Sep-15, Volume: 5

    Topics: Animals; Cocaine; Conditioning, Psychological; Disease Models, Animal; Fear; Female; Mice; Mice, Inbred C57BL; Neurodevelopmental Disorders; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Reward; Schizophrenia; Sucrose

2015
Rats quit nicotine for a sweet reward following an extensive history of nicotine use.
    Addiction biology, 2017, Volume: 22, Issue:1

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Choice Behavior; Disease Models, Animal; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sweetening Agents

2017
Reward memory relieves anxiety-related behavior through synaptic strengthening and protein kinase C in dentate gyrus.
    Hippocampus, 2016, Volume: 26, Issue:4

    Topics: Animals; Anxiety Disorders; Benzophenanthridines; Dendritic Spines; Dentate Gyrus; Disease Models, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Male; Maze Learning; Memory; Mice, Inbred DBA; Protein Kinase C; Protein Kinase Inhibitors; Reward; Synapses; Up-Regulation

2016
Reward related neurotransmitter changes in a model of depression: An in vivo microdialysis study.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2015, Volume: 16, Issue:7

    Topics: Animals; Depression; Disease Models, Animal; Dopamine; Dopamine Agents; gamma-Aminobutyric Acid; Glutamic Acid; Male; Methamphetamine; Microdialysis; Neurotransmitter Agents; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Self Administration; Serotonin

2015
Differential mesocorticolimbic responses to palatable food in binge eating prone and binge eating resistant female rats.
    Physiology & behavior, 2015, Dec-01, Volume: 152, Issue:Pt A

    Topics: Animal Feed; Animals; Binge-Eating Disorder; Disease Models, Animal; Eating; Feeding Behavior; Female; Food; Genetic Predisposition to Disease; Immunohistochemistry; Nucleus Accumbens; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Reward; Species Specificity

2015
The rewarding properties of methamphetamine in an invertebrate model of drug addiction.
    Physiology & behavior, 2016, Jan-01, Volume: 153

    Topics: Animals; Astacoidea; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methamphetamine; Microdialysis; Motivation; Reward; Spatial Behavior; Substance-Related Disorders

2016
Effects of the phencyclidine model of schizophrenia and nicotine on total and categorized ultrasonic vocalizations in rats.
    Behavioural pharmacology, 2016, Volume: 27, Issue:4

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hallucinogens; Male; Nicotine; Phencyclidine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Schizophrenia; Smoking; Ultrasonics; Vocalization, Animal

2016
Orexin signaling is necessary for hypoglycemia-induced prevention of conditioned place preference.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2016, Jan-01, Volume: 310, Issue:1

    Topics: Animals; Arousal; Behavior, Animal; Benzoxazoles; Blood Glucose; Brain; Conditioning, Psychological; Disease Models, Animal; Feeding Behavior; Hypoglycemia; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Rats, Sprague-Dawley; Reward; Sertraline; Signal Transduction; Time Factors; Urea

2016
Automated quantitative analysis to assess motor function in different rat models of impaired coordination and ataxia.
    Journal of neuroscience methods, 2016, 08-01, Volume: 268

    Topics: Animals; Animals, Genetically Modified; Ataxia; Biomechanical Phenomena; Disease Models, Animal; Environment; Equipment Design; Ethanol; Gait; Housing, Animal; Male; Pattern Recognition, Automated; Rats, Sprague-Dawley; Rats, Wistar; Reward

2016
Cannabidiol disrupts the reconsolidation of contextual drug-associated memories in Wistar rats.
    Addiction biology, 2017, Volume: 22, Issue:3

    Topics: Animals; Cannabidiol; Cocaine; Conditioning, Classical; Cues; Disease Models, Animal; Male; Memory; Mental Recall; Morphine; Naltrexone; Rats; Rats, Wistar; Reward

2017
Sex-specific attentional deficits in adult vitamin D deficient BALB/c mice.
    Physiology & behavior, 2016, Apr-01, Volume: 157

    Topics: Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Body Weight; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Eating; Exploratory Behavior; Female; Food Deprivation; Male; Mice; Mice, Inbred BALB C; Reaction Time; Reward; Sex Characteristics; Vitamin D; Vitamin D Deficiency

2016
A thalamic input to the nucleus accumbens mediates opiate dependence.
    Nature, 2016, Feb-11, Volume: 530, Issue:7589

    Topics: Animals; Avoidance Learning; Disease Models, Animal; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Morphine; Neural Pathways; Neuronal Plasticity; Neurons; Nucleus Accumbens; Opioid-Related Disorders; Optogenetics; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Reward; Substance Withdrawal Syndrome; Synaptic Transmission; Thalamus

2016
Effect of electroconvulsive seizures on cognitive flexibility.
    Hippocampus, 2016, Volume: 26, Issue:7

    Topics: Animals; Bromodeoxyuridine; Cell Count; Choice Behavior; Cognition; Conditioning, Operant; Discrimination, Psychological; Disease Models, Animal; Electroconvulsive Therapy; Executive Function; Hippocampus; Immunohistochemistry; Male; Neurogenesis; Neuropsychological Tests; Rats; Reversal Learning; Reward; Seizures; Space Perception

2016
Perseveration of craving: effects of stimuli conditioned to drugs of abuse versus conventional reinforcers differing in demand.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Craving; Cues; Dietary Sugars; Disease Models, Animal; Ethanol; Male; Motivation; Rats; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration; Water

2017
Dyadic social interaction of C57BL/6 mice versus interaction with a toy mouse: conditioned place preference/aversion, substrain differences, and no development of a hierarchy.
    Behavioural pharmacology, 2016, Volume: 27, Issue:2-3 Spec I

    Topics: Affect; Animals; Conditioning, Operant; Disease Models, Animal; Dominance-Subordination; Interpersonal Relations; Male; Mice; Mice, Inbred Strains; Play and Playthings; Reproducibility of Results; Reward; Species Specificity; Substance-Related Disorders

2016
STEP signaling pathway mediates psychomotor stimulation and morphine withdrawal symptoms, but not for reward, analgesia and tolerance.
    Experimental & molecular medicine, 2016, Feb-26, Volume: 48

    Topics: Analgesia; Analgesics, Opioid; Animals; Corpus Striatum; Disease Models, Animal; Drug Resistance; Female; Male; Mice; Mice, Knockout; Morphine; Phosphorylation; Point Mutation; Protein Tyrosine Phosphatases, Non-Receptor; Psychomotor Agitation; Receptors, Opioid; Reward; Signal Transduction; Substance Withdrawal Syndrome

2016
Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice.
    Journal of visualized experiments : JoVE, 2016, Feb-18, Issue:108

    Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Conditioning, Psychological; Disease Models, Animal; Drug-Seeking Behavior; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Reward; Substance-Related Disorders

2016
Chronic mitragynine (kratom) enhances punishment resistance in natural reward seeking and impairs place learning in mice.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Learning; Male; Mice; Punishment; Reward; Secologanin Tryptamine Alkaloids; Substance-Related Disorders

2017
[The novel method female encounter test].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2016, Volume: 147, Issue:4

    Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dopamine; Female; Male; Mice; Reward; Sex Characteristics

2016
The behavioral effects of a mixed efficacy antinociceptive peptide, VRP26, following chronic administration in mice.
    Psychopharmacology, 2016, Volume: 233, Issue:13

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Female; Fentanyl; Male; Mice; Mice, Inbred C57BL; Motor Activity; Narcotic Antagonists; Peptides, Cyclic; Receptors, Opioid, delta; Receptors, Opioid, mu; Reward

2016
Compromised Dopaminergic Encoding of Reward Accompanying Suppressed Willingness to Overcome High Effort Costs Is a Prominent Prodromal Characteristic of the Q175 Mouse Model of Huntington's Disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 05-04, Volume: 36, Issue:18

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Extracellular Space; Feeding Behavior; Humans; Huntington Disease; Locomotion; Male; Mice; Motivation; Nucleus Accumbens; Prodromal Symptoms; Reward

2016
`Up-regulation of histone acetylation induced by social defeat mediates the conditioned rewarding effects of cocaine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 10-03, Volume: 70

    Topics: Acetylation; Animals; Central Nervous System Stimulants; Cerebral Cortex; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dominance-Subordination; Epigenesis, Genetic; Hippocampus; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Male; Mice; Reward; Spatial Behavior; Stress, Psychological; Up-Regulation; Valproic Acid

2016
Stress Degrades Prefrontal Cortex Neuronal Coding of Goal-Directed Behavior.
    Cerebral cortex (New York, N.Y. : 1991), 2017, 05-01, Volume: 27, Issue:5

    Topics: Action Potentials; Analysis of Variance; Animals; Choice Behavior; Corticotropin-Releasing Hormone; Disease Models, Animal; Goals; Male; Maze Learning; Memory, Short-Term; Neurons; Noise; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Stress, Psychological

2017
Differential effects of the pharmacological stressor yohimbine on impulsive decision making and response inhibition.
    Psychopharmacology, 2016, Volume: 233, Issue:14

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Attention Deficit Disorder with Hyperactivity; Choice Behavior; Decision Making; Disease Models, Animal; Impulsive Behavior; Inhibition, Psychological; Male; Rats; Rats, Wistar; Reaction Time; Reward; Yohimbine

2016
Towards the development of improved tests for negative symptoms of schizophrenia in a validated animal model.
    Behavioural brain research, 2016, 10-01, Volume: 312

    Topics: Affect; Animals; Behavior, Animal; Disease Models, Animal; Female; Phencyclidine; Rats; Reward; Schizophrenia; Schizophrenic Psychology

2016
Activation of the reward system boosts innate and adaptive immunity.
    Nature medicine, 2016, Volume: 22, Issue:8

    Topics: Adaptive Immunity; Animals; Antibodies, Bacterial; Bacteria; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Escherichia coli; Flow Cytometry; Hypersensitivity, Delayed; Immunity, Innate; Immunohistochemistry; Macrophages; Mice; Monocytes; Phagocytosis; Placebo Effect; Reward; Sympathectomy, Chemical; Sympathetic Nervous System; T-Lymphocytes; Ventral Tegmental Area

2016
Amelioration of scopolamine-induced amnesia by phosphatidylserine and curcumin in the day-old chick.
    Behavioural pharmacology, 2016, Volume: 27, Issue:6

    Topics: Alzheimer Disease; Amnesia; Animals; Avoidance Learning; Chickens; Cholinergic Antagonists; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Memory; Phosphatidylserines; Reward; Scopolamine

2016
Hypofrontality and Posterior Hyperactivity in Early Schizophrenia: Imaging and Behavior in a Preclinical Model.
    Biological psychiatry, 2017, 03-15, Volume: 81, Issue:6

    Topics: Animals; Behavior, Animal; Biomarkers; Brain; Decision Making; Diffusion Tensor Imaging; Disease Models, Animal; Female; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methylazoxymethanol Acetate; Multimodal Imaging; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reversal Learning; Reward; Schizophrenia; Schizophrenic Psychology

2017
Overexpression of CRF in the BNST diminishes dysphoria but not anxiety-like behavior in nicotine withdrawing rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:9

    Topics: Animals; Anxiety; Corticotropin-Releasing Hormone; Dependovirus; Disease Models, Animal; Genetic Vectors; Male; Mecamylamine; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Receptors, Nicotinic; Reward; Self Stimulation; Septal Nuclei; Substance Withdrawal Syndrome; Tobacco Use Disorder

2016
Role of dopamine neurotransmission in the long-term effects of repeated social defeat on the conditioned rewarding effects of cocaine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 11-03, Volume: 71

    Topics: Age Factors; Animals; Benzazepines; Cerebral Cortex; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hippocampus; Male; Mice; Raclopride; Receptors, Dopamine; Reward; Statistics, Nonparametric; Stress, Psychological

2016
Hedonic and motivational responses to food reward are unchanged in rats with neuropathic pain.
    Pain, 2016, Volume: 157, Issue:12

    Topics: Animals; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Food; Freund's Adjuvant; Male; Motivation; Neuralgia; Pain Measurement; Rats; Rats, Sprague-Dawley; Reward; Spinal Nerves; Sucrose; Taste; Time Factors

2016
The infralimbic and prelimbic cortices contribute to the inhibitory control of cocaine-seeking behavior during a discriminative stimulus task in rats.
    Addiction biology, 2017, Volume: 22, Issue:6

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Discrimination, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward

2017
Morphine treatment enhances glutamatergic input onto neurons of the nucleus accumbens via both disinhibitory and stimulating effect.
    Addiction biology, 2017, Volume: 22, Issue:6

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Glutamic Acid; Male; Morphine; Neurons; Nucleus Accumbens; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reward; Synaptic Transmission

2017
Dopamine D1 and D3 receptor interactions in cocaine reward and seeking in rats.
    Psychopharmacology, 2016, Volume: 233, Issue:23-24

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Drug Therapy, Combination; Drug-Seeking Behavior; Fluorenes; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D3; Reinforcement, Psychology; Reward

2016
Topiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness.
    Psychopharmacology, 2016, Volume: 233, Issue:23-24

    Topics: Analysis of Variance; Animals; Anticonvulsants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Fructose; Male; Mice; Reward; Topiramate; Ventral Tegmental Area

2016
Choice between delayed food and immediate oxycodone in rats.
    Psychopharmacology, 2016, Volume: 233, Issue:23-24

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Choice Behavior; Delay Discounting; Disease Models, Animal; Eating; Feeding Behavior; Humans; Male; Naltrexone; Oxycodone; Rats; Reward; Time Factors

2016
Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:4

    Topics: Animals; Depression; Disease Models, Animal; Down-Regulation; Epigenesis, Genetic; Histone Demethylases; Male; Mice; Mice, Inbred C57BL; Reward; Stress, Psychological

2017
Activity-Based Anorexia Alters the Expression of BDNF Transcripts in the Mesocorticolimbic Reward Circuit.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Animals; Anorexia; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Gene Expression; Gene Expression Regulation; Mice; Motor Activity; Physical Exertion; Reward

2016
The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in male rats.
    Behavioural brain research, 2017, 03-01, Volume: 320

    Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Locomotion; Male; Methamphetamine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Varenicline

2017
Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists.
    Neuropharmacology, 2017, Volume: 116

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cannabinoid Receptor Agonists; Chronic Pain; Constipation; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Indoles; Male; Mice, Inbred ICR; Morphine; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Opioid, mu; Reward

2017
Behavioral and physiological consequences of enrichment loss in rats.
    Psychoneuroendocrinology, 2017, Volume: 77

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Diet; Disease Models, Animal; Environment; Feeding Behavior; Housing, Animal; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Rats; Reward; Social Behavior; Stress, Psychological

2017
Patterned feeding induces neuroendocrine, behavioral and genetic changes that promote palatable food intake.
    International journal of obesity (2005), 2017, Volume: 41, Issue:3

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Eating; Feeding Behavior; Ghrelin; Male; Obesity; Rats; Rats, Long-Evans; Receptors, Ghrelin; Reward

2017
Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancer.
    Journal of pharmacological sciences, 2017, Volume: 133, Issue:1

    Topics: Analgesics; Animals; Butadienes; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Mice; Morphine; Nitriles; Oxycodone; Phosphorylation; Radioligand Assay; Receptors, Opioid, mu; Reward; Up-Regulation; Ventral Tegmental Area

2017
A Simple Way to Measure Alterations in Reward-seeking Behavior Using Drosophila melanogaster.
    Journal of visualized experiments : JoVE, 2016, 12-15, Issue:118

    Topics: Alcoholism; Animals; Behavior, Animal; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Ethanol; Reward; Self Administration

2016
Effects of the chronic restraint stress induced depression on reward-related learning in rats.
    Behavioural brain research, 2017, 03-15, Volume: 321

    Topics: Animals; Chronic Disease; Conditioning, Classical; Conditioning, Operant; Depressive Disorder; Disease Models, Animal; Habituation, Psychophysiologic; Learning Disabilities; Male; Motor Activity; Random Allocation; Rats, Wistar; Restraint, Physical; Reward; Stress, Psychological

2017
A single cocaine exposure disrupts actin dynamics in the cortico-accumbal pathway of adolescent rats: modulation by a second cocaine injection.
    Psychopharmacology, 2017, Volume: 234, Issue:8

    Topics: Actins; Analysis of Variance; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward

2017
Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats.
    Psychopharmacology, 2017, Volume: 234, Issue:8

    Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Psychological; Disease Models, Animal; Goals; Hippocampus; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Reward

2017
Modeling human methamphetamine use patterns in mice: chronic and binge methamphetamine exposure, reward function and neurochemistry.
    Addiction biology, 2018, Volume: 23, Issue:1

    Topics: Amphetamine-Related Disorders; Animals; Brain; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Glutamine; Methamphetamine; Mice; Reward; Self Stimulation; Serotonin

2018
MGM-9 [(E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate], a derivative of the indole alkaloid mitragynine: a novel dual-acting mu- and kappa-opioid agonist with pot
    Neuropharmacology, 2008, Volume: 55, Issue:2

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Tolerance; Gastrointestinal Transit; Guinea Pigs; Male; Mice; Morphine; Morphine Derivatives; Pain; Pain Measurement; Pain Threshold; Protein Binding; Reaction Time; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Secologanin Tryptamine Alkaloids; Time Factors

2008
Anhedonia and activity deficits in rats: impact of post-stroke depression.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3

    Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Citalopram; Depression; Disease Models, Animal; Male; Middle Cerebral Artery; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Social Isolation; Stress, Psychological; Stroke; Sucrose

2009
Dopaminergic and serotonergic modulation of persistent behaviour in the reinforced spatial alternation model of obsessive-compulsive disorder.
    Psychopharmacology, 2008, Volume: 200, Issue:4

    Topics: Animals; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Fluoxetine; Male; Maze Learning; Obsessive-Compulsive Disorder; Piperazines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Time Factors

2008
Propranolol transiently inhibits reinstatement of nicotine-seeking behaviour in rats.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Addictive; Disease Models, Animal; Extinction, Psychological; Feeding Behavior; Male; Nicotine; Nicotinic Agonists; Propranolol; Rats; Rats, Sprague-Dawley; Reward; Secondary Prevention; Self Administration; Smoking; Smoking Prevention

2010
Attenuation of high sweet solution preference by mood stabilizers: a possible mouse model for the increased reward-seeking domain of mania.
    Journal of neuroscience methods, 2009, Feb-15, Volume: 177, Issue:1

    Topics: Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Food Preferences; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Reward; Saccharin; Sweetening Agents

2009
Effect of high-fat diet during gestation, lactation, or postweaning on physiological and behavioral indexes in borderline hypertensive rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:1

    Topics: Adiposity; Age Factors; Aging; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Blood Pressure; Body Weight; Conditioning, Operant; Dietary Fats; Disease Models, Animal; Feeding Behavior; Female; Hybridization, Genetic; Hyperphagia; Hypertension; Insulin; Lactation; Leptin; Male; Maternal Nutritional Physiological Phenomena; Metabolic Syndrome; Motivation; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred SHR; Rats, Wistar; Reward; Weaning

2009
Distinct subsets of nucleus accumbens neurons encode operant responding for ethanol versus water.
    The European journal of neuroscience, 2008, Volume: 28, Issue:9

    Topics: Action Potentials; Alcohol-Induced Disorders, Nervous System; Animals; Central Nervous System Depressants; Conditioning, Operant; Cues; Disease Models, Animal; Ethanol; Male; Neurons; Neuropsychological Tests; Nucleus Accumbens; Rats; Rats, Long-Evans; Reinforcement, Psychology; Reward; Space Perception; Water

2008
Regulation of synaptic connectivity with chronic cocaine.
    The American journal of psychiatry, 2008, Volume: 165, Issue:11

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendritic Spines; Disease Models, Animal; Gene Expression; Humans; MEF2 Transcription Factors; Myogenic Regulatory Factors; Neuronal Plasticity; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D5; Reward; Signal Transduction; Synaptic Transmission

2008
The role of nicotine in smoking: a dual-reinforcement model.
    Nebraska Symposium on Motivation. Nebraska Symposium on Motivation, 2009, Volume: 55

    Topics: Animals; Association Learning; Conditioning, Psychological; Cues; Disease Models, Animal; Ganglionic Stimulants; Humans; Motivation; Nicotine; Rats; Reward; Self Administration; Smoking; Smoking Cessation; Social Environment; Substance Withdrawal Syndrome; Tobacco Use Disorder

2009
Selective dopamine D4 receptor agonist (A-412997) improves cognitive performance and stimulates motor activity without influencing reward-related behaviour in rat.
    Behavioural pharmacology, 2008, Volume: 19, Issue:8

    Topics: Acetamides; Acetylcholine; Amphetamine; Animals; Behavior, Animal; Cognition; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Routes; Extracellular Fluid; Male; Memory Disorders; Methylphenidate; Microdialysis; Motor Activity; Pattern Recognition, Visual; Photic Stimulation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4; Reward

2008
Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat.
    Journal of neurochemistry, 2009, Volume: 108, Issue:4

    Topics: Aging; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Animals, Newborn; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Drug Administration Schedule; Ethanol; Glutamic Acid; Limbic System; Male; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Synaptic Transmission; Ventral Tegmental Area

2009
Methylphenidate to adolescent rats drives enduring changes of accumbal Htr7 expression: implications for impulsive behavior and neuronal morphology.
    Genes, brain, and behavior, 2009, Volume: 8, Issue:3

    Topics: Aging; Animals; Behavior, Animal; Cell Enlargement; Cells, Cultured; Central Nervous System Stimulants; Disease Models, Animal; Female; Impulsive Behavior; Male; Methylphenidate; Neurites; Neuronal Plasticity; Neurons; Nucleus Accumbens; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Serotonin; Reward; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2009
Amygdala protein kinase C epsilon controls alcohol consumption.
    Genes, brain, and behavior, 2009, Volume: 8, Issue:5

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Amygdala; Animals; Brain Chemistry; Central Nervous System Depressants; Conditioning, Psychological; Disease Models, Animal; Ethanol; Gene Frequency; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Kinase C-epsilon; Reward

2009
Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Recurrence; Reward; Self Administration; Substance Withdrawal Syndrome

2009
GDNF is an endogenous negative regulator of ethanol-mediated reward and of ethanol consumption after a period of abstinence.
    Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:6

    Topics: Alcohol Drinking; Alcoholism; Animals; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Haploidy; Male; Mice; Mice, Knockout; Mice, Transgenic; Motor Activity; Reward

2009
Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain.
    Neuroscience, 2009, Jul-07, Volume: 161, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Chronic Disease; Cognition; Decision Making; Disease Models, Animal; Dopamine; Freund's Adjuvant; Gambling; Hydroxyindoleacetic Acid; Male; Neuropsychological Tests; Nucleus Accumbens; Pain; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Time Factors

2009
Simultaneous anhedonia and exaggerated locomotor activation in an animal model of depression.
    Psychopharmacology, 2009, Volume: 205, Issue:2

    Topics: Amphetamine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Body Weight; Central Nervous System Stimulants; Conditioning, Operant; CREB-Binding Protein; Depression; Disease Models, Animal; Food Preferences; Gene Expression Regulation; Locomotion; Male; Olfactory Bulb; Quinine; Rats; Rats, Sprague-Dawley; Reward; Sucrose; Sweetening Agents

2009
DRL performance of spontaneously hypertensive rats: dissociation of timing and inhibition of responses.
    Behavioural brain research, 2009, Jul-19, Volume: 201, Issue:1

    Topics: Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervous System Stimulants; Disease Models, Animal; Impulsive Behavior; Male; Methylphenidate; Models, Psychological; Neuropsychological Tests; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Reinforcement Schedule; Reward; Species Specificity; Time Factors

2009
The encoding of cocaine vs. natural rewards in the striatum of nonhuman primates: categories with different activations.
    Neuroscience, 2009, Sep-29, Volume: 163, Issue:1

    Topics: Action Potentials; Animals; Basal Ganglia; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Neural Pathways; Neurons; Neuropsychological Tests; Photic Stimulation; Reinforcement, Psychology; Reward; Signal Processing, Computer-Assisted

2009
Role of dopamine D(1)-family receptors in dorsolateral striatum in context-induced reinstatement of heroin seeking in rats.
    Psychopharmacology, 2009, Volume: 206, Issue:1

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Conditioning, Psychological; Corpus Striatum; Disease Models, Animal; Extinction, Psychological; Heroin; Heroin Dependence; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Reinforcement Schedule; Reward; Secondary Prevention; Self Administration

2009
Cocaine- and amphetamine-regulated transcript peptide immunoreactivity in the brain of the CCK-1 receptor deficient obese OLETF rat.
    Experimental brain research, 2009, Volume: 196, Issue:4

    Topics: Amygdala; Animals; Appetite Regulation; Axons; Brain; Chemokines, CC; Disease Models, Animal; Immunohistochemistry; Male; Nerve Tissue Proteins; Neural Pathways; Nucleus Accumbens; Obesity; Rats; Rats, Inbred OLETF; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Reward; Satiety Response; Solitary Nucleus; Taste; Visceral Afferents

2009
N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats.
    Neuropharmacology, 2010, Volume: 58, Issue:1

    Topics: Animals; Behavior, Addictive; Brain; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Male; Microdialysis; Neuroprotective Agents; Organophosphorus Compounds; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration

2010
A neurocomputational model for cocaine addiction.
    Neural computation, 2009, Volume: 21, Issue:10

    Topics: Algorithms; Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Computer Simulation; Decision Making; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Humans; Impulsive Behavior; Learning; Reinforcement, Psychology; Reward

2009
Low or high cocaine responding rats differ in striatal extracellular dopamine levels and dopamine transporter number.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Extracellular Space; Male; Microdialysis; Motor Activity; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Reward

2009
An animal model of compulsive food-taking behaviour.
    Addiction biology, 2009, Volume: 14, Issue:4

    Topics: Animals; Binge-Eating Disorder; Body Weight; Choice Behavior; Compulsive Behavior; Disease Models, Animal; Ethanol; Feeding Behavior; Female; Obesity; Rats; Rats, Wistar; Reward; Sucrose; Taste

2009
Unmasking the tonic-aversive state in neuropathic pain.
    Nature neuroscience, 2009, Volume: 12, Issue:11

    Topics: Adenosine; Analgesics; Analysis of Variance; Animals; Calcium Channel Blockers; Clonidine; Conditioning, Classical; Conditioning, Psychological; Disease Models, Animal; Drug Administration Schedule; Hyperalgesia; Injections, Spinal; Male; Neuralgia; omega-Conotoxins; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Time Factors

2009
An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:2

    Topics: Animals; Behavior, Addictive; Conditioning, Classical; Cues; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Genetics, Behavioral; Impulsive Behavior; Male; Phenotype; Psychomotor Performance; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reward; RNA, Messenger

2010
Cerebellar damage loosens the strategic use of the spatial structure of the search space.
    Cerebellum (London, England), 2010, Volume: 9, Issue:1

    Topics: Animals; Association Learning; Behavior, Animal; Cerebellar Diseases; Cerebellum; Cognition; Denervation; Discrimination Learning; Disease Models, Animal; Executive Function; Exploratory Behavior; Functional Laterality; Male; Maze Learning; Orientation; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Reward; Space Perception; Spatial Behavior; Species Specificity

2010
Footshock stress potentiates cue-induced cocaine-seeking in an animal model of relapse.
    Physiology & behavior, 2009, Dec-07, Volume: 98, Issue:5

    Topics: Anesthetics, Local; Animals; Behavior, Addictive; Biophysics; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Electroshock; Extinction, Psychological; Male; Multivariate Analysis; Rats; Rats, Long-Evans; Reward; Secondary Prevention; Self Administration; Stress, Psychological

2009
Antidepressant-like effects of 3,6'-disinapoyl sucrose on hippocampal neuronal plasticity and neurotrophic signal pathway in chronically mild stressed rats.
    Neurochemistry international, 2010, Volume: 56, Issue:3

    Topics: Animals; Antidepressive Agents; Appetite Regulation; Brain-Derived Neurotrophic Factor; Coumaric Acids; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Laminin; Nerve Growth Factors; Neural Cell Adhesion Molecules; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger; Signal Transduction; Stress, Psychological; Sucrose

2010
Revisiting intragastric ethanol intubation as a dependence induction method for studies of ethanol reward and motivation in rats.
    Alcoholism, clinical and experimental research, 2010, Mar-01, Volume: 34, Issue:3

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Anxiety; Artifacts; Body Weight; Central Nervous System Depressants; Circadian Rhythm; Disease Models, Animal; Ethanol; Intubation, Gastrointestinal; Male; Motivation; Rats; Rats, Wistar; Reward; Stress, Psychological; Substance Withdrawal Syndrome

2010
Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:4

    Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Administration Schedule; Flupenthixol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motivation; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine D2; Reward; Signal Transduction; Tobacco Use Disorder

2010
The role of the striatum in compulsive behavior in intact and orbitofrontal-cortex-lesioned rats: possible involvement of the serotonergic system.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:4

    Topics: Animals; Compulsive Behavior; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Extinction, Psychological; Feeding Behavior; GABA Agonists; Male; Microinjections; Muscimol; Neurotransmitter Agents; Paroxetine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Selective Serotonin Reuptake Inhibitors

2010
Effect of prenatal stress on alcohol preference and sensitivity to chronic alcohol exposure in male rats.
    Psychopharmacology, 2011, Volume: 214, Issue:1

    Topics: Alcohol Drinking; Animals; Disease Models, Animal; Ethanol; Female; Male; Motor Activity; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Restraint, Physical; Reward; Stress, Psychological; Transaminases

2011
Stress triggers anhedonia in rats bred for learned helplessness.
    Behavioural brain research, 2010, May-01, Volume: 209, Issue:1

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Depression; Disease Models, Animal; Electroshock; Food Preferences; Helplessness, Learned; Rats; Reflex, Startle; Reward; Stress, Psychological

2010
Analysis of licking microstructure provides no evidence for a reduction in reward value following acute or sub-chronic phencyclidine administration.
    Psychopharmacology, 2010, Volume: 209, Issue:2

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Feeding Behavior; Male; Motor Activity; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Schizophrenia; Schizophrenic Psychology; Sucrose; Taste; Time Factors

2010
RACK1, a potential target to decrease morphine reward in mice.
    Archives italiennes de biologie, 2009, Volume: 147, Issue:4

    Topics: Animals; Brain; Conditioning, Operant; Disease Models, Animal; Drug Administration Schedule; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinases; Morphine; Morphine Dependence; Narcotics; Neuropeptides; Receptors for Activated C Kinase; Reward

2009
Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats.
    Nature neuroscience, 2010, Volume: 13, Issue:5

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Compulsive Behavior; Conditioning, Operant; Corpus Striatum; Diet; Disease Models, Animal; Down-Regulation; Electric Stimulation; Energy Intake; Feeding Behavior; Food Preferences; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hypothalamus; Male; Obesity; Phosphopyruvate Hydratase; Rats; Rats, Wistar; Receptors, Dopamine D2; Reward; RNA, Small Nuclear; Weight Gain

2010
NMDA receptor hypofunction in the prelimbic cortex increases sensitivity to the rewarding properties of opiates via dopaminergic and amygdalar substrates.
    Cerebral cortex (New York, N.Y. : 1991), 2011, Volume: 21, Issue:1

    Topics: Amygdala; Analgesics, Opioid; Animals; Conditioning, Operant; Disease Models, Animal; Dopamine; Glutamic Acid; Male; Opioid-Related Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward

2011
Graft-mediated functional recovery on a skilled forelimb use paradigm in a rodent model of Parkinson's disease is dependent on reward contingency.
    Behavioural brain research, 2010, Oct-15, Volume: 212, Issue:2

    Topics: Animals; Brain Tissue Transplantation; Cell Transplantation; Disability Evaluation; Disease Models, Animal; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Medial Forebrain Bundle; Mesencephalon; Motor Skills; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Recovery of Function; Reward

2010
Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:9

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Dynorphins; Exploratory Behavior; Male; Mental Recall; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Reward; Stress, Psychological; Swimming

2010
Can satellite glial cells be therapeutic targets for pain control?
    Neuron glia biology, 2010, Volume: 6, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell- and Tissue-Based Therapy; Connexin 43; Disease Models, Animal; Ectodysplasins; Facial Pain; Gap Junctions; Glutamate Synthase; Male; Membrane Cofactor Protein; Models, Biological; Neuroglia; Pain; Pain Management; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Reward; RNA, Double-Stranded; Small-Conductance Calcium-Activated Potassium Channels; Trigeminal Ganglion

2010
Deep brain stimulation of the nucleus accumbens reduces alcohol intake in alcohol-preferring rats.
    Neurosurgical focus, 2010, Volume: 29, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Animals; Conditioning, Operant; Deep Brain Stimulation; Disease Models, Animal; Drinking Behavior; Ethanol; Humans; Male; Nucleus Accumbens; Rats; Reward; Stereotaxic Techniques; Water

2010
Erythropoietin reverses the attentional set-shifting impairment in a rodent schizophrenia disease-like model.
    Psychopharmacology, 2010, Volume: 212, Issue:4

    Topics: Animals; Antipsychotic Agents; Attention; Behavior, Animal; Benzhydryl Compounds; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epoetin Alfa; Erythropoietin; Executive Function; Haloperidol; Male; Modafinil; Neuropsychological Tests; Phencyclidine; Rats; Recombinant Proteins; Reward; Schizophrenia; Schizophrenic Psychology

2010
Therapeutic-like properties of a dopamine uptake inhibitor in animal models of amphetamine addiction.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:5

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Benztropine; Conditioning, Psychological; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Mice; Motor Activity; Nucleus Accumbens; Rats; Reward; Self Administration

2011
Effects of the novel endocannabinoid uptake inhibitor, LY2183240, on fear-potentiated startle and alcohol-seeking behaviors in mice selectively bred for high alcohol preference.
    Psychopharmacology, 2010, Volume: 212, Issue:4

    Topics: Acoustic Stimulation; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cannabinoid Receptor Modulators; Comorbidity; Conditioning, Psychological; Disease Models, Animal; Endocannabinoids; Ethanol; Female; Heterocyclic Compounds, 1-Ring; Male; Mice; Motor Activity; Reflex, Startle; Reward; Time Factors; Urea

2010
Memory for reward location is enhanced even though acetylcholine efflux within the amygdala is impaired in rats with damage to the diencephalon produced by thiamine deficiency.
    Neurobiology of learning and memory, 2010, Volume: 94, Issue:4

    Topics: Acetylcholine; Amnesia; Amygdala; Animals; Antimetabolites; Association Learning; Brain Damage, Chronic; Cholinergic Fibers; Diencephalon; Disease Models, Animal; Male; Maze Learning; Memory; Problem Solving; Pyrithiamine; Random Allocation; Rats; Rats, Sprague-Dawley; Reward; Thiamine Deficiency

2010
Focus on the positive: computational simulations implicate asymmetrical reward prediction error signals in childhood attention-deficit/hyperactivity disorder.
    Brain research, 2010, Dec-13, Volume: 1365

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Child; Computer Simulation; Disease Models, Animal; Dopamine; Humans; Models, Psychological; Neural Pathways; Psychomotor Performance; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reward

2010
Prolonged attenuation of the reinforcing strength of cocaine by chronic d-amphetamine in rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Dextroamphetamine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Macaca mulatta; Male; Reinforcement, Psychology; Reward; Self Administration; Time Factors

2011
Coping with sleep deprivation: shifts in regional brain activity and learning strategy.
    Sleep, 2010, Volume: 33, Issue:11

    Topics: Adaptation, Psychological; Animals; Behavior, Animal; Biomarkers; Brain; Corpus Striatum; Corticosterone; CREB-Binding Protein; Disease Models, Animal; Hippocampus; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Reversal Learning; Reward; Sleep Deprivation

2010
Gambling rats: insight into impulsive and addictive behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:1

    Topics: Animals; Decision Making; Disease Models, Animal; Dopamine; Dopamine Agents; Gambling; Humans; Impulsive Behavior; Motivation; Neuropsychological Tests; Rats; Reward; Serotonin; Serotonin Agents; Substance-Related Disorders

2011
Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Dec-08, Volume: 30, Issue:49

    Topics: Action Potentials; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Benzazepines; Brain; Cardiotonic Agents; Chronic Disease; Disease Models, Animal; Disease Susceptibility; Dopamine; Electric Stimulation; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurons; Patch-Clamp Techniques; Pyrimidines; Reward; Stress, Psychological; Ventral Tegmental Area

2010
The first universal opioid ligand, (2S)-2-[(5R,6R,7R,14S)-N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3,3-dimethylpentan-2-ol (BU08028): characterization of the in vitro profile and in vivo behavioral effects in mouse mode
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:3

    Topics: Acute Disease; Analgesics, Opioid; Animals; Buprenorphine; CHO Cells; Cocaine; Cricetinae; Cricetulus; Disease Models, Animal; Humans; Ligands; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Protein Binding; Receptors, Opioid; Reward

2011
Reverse-translational biomarker validation of Abnormal Repetitive Behaviors in mice: an illustration of the 4P's modeling approach.
    Behavioural brain research, 2011, Jun-01, Volume: 219, Issue:2

    Topics: Affect; Animals; Autistic Disorder; Biomarkers; Compulsive Behavior; Cues; Discrimination, Psychological; Disease Models, Animal; Feeding Behavior; Gambling; Mice; Mice, Inbred C57BL; Models, Neurological; Obsessive-Compulsive Disorder; Psychomotor Performance; Reward; Set, Psychology; Stereotyped Behavior; Trichotillomania

2011
Dorsal as well as ventral striatal lesions affect levels of intravenous cocaine and morphine self-administration in rats.
    Neuroscience letters, 2011, Apr-08, Volume: 493, Issue:1-2

    Topics: Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Morphine; Narcotics; Neostriatum; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Substance-Related Disorders

2011
Continuous, but not intermittent, antipsychotic drug delivery intensifies the pursuit of reward cues.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:6

    Topics: Animals; Antipsychotic Agents; Corpus Striatum; Cues; Disease Models, Animal; Dopamine; Drug Administration Schedule; Drug Synergism; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward; Substantia Nigra

2011
Synaptic potentiation onto habenula neurons in the learned helplessness model of depression.
    Nature, 2011, Feb-24, Volume: 470, Issue:7335

    Topics: Animals; Avoidance Learning; Deep Brain Stimulation; Depression; Disease Models, Animal; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Helplessness, Learned; Male; Models, Neurological; Neuroanatomical Tract-Tracing Techniques; Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Reward; Synapses; Synaptic Transmission; Thalamus; Ventral Tegmental Area

2011
Direct effect of nicotine on mesolimbic dopamine release in rat nucleus accumbens shell.
    Neuroscience letters, 2011, Apr-08, Volume: 493, Issue:1-2

    Topics: Animals; Disease Models, Animal; Dopamine; Male; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Tobacco Use Disorder

2011
Expression of the gene encoding the ghrelin receptor in rats selected for differential alcohol preference.
    Behavioural brain research, 2011, Aug-01, Volume: 221, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Choice Behavior; Disease Models, Animal; Ethanol; Gene Expression; Ghrelin; Male; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Ghrelin; Reward

2011
Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia.
    Biological psychiatry, 2011, May-15, Volume: 69, Issue:10

    Topics: Affective Symptoms; Aminopyridines; Analysis of Variance; Animals; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Gene Expression; Indoles; Mice; Mice, Transgenic; Motivation; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Reward; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Up-Regulation

2011
Why does depression hurt? Ancestral primary-process separation-distress (PANIC/GRIEF) and diminished brain reward (SEEKING) processes in the genesis of depressive affect.
    Psychiatry, 2011,Spring, Volume: 74, Issue:1

    Topics: Affect; Animals; Biological Evolution; Brain; Buprenorphine; Depression; Disease Models, Animal; Grief; Humans; Models, Neurological; Panic; Reward

2011
A Drosophila model for alcohol reward.
    Nature neuroscience, 2011, Volume: 14, Issue:5

    Topics: Alcohol-Related Disorders; Alcohols; Analysis of Variance; Animals; Animals, Genetically Modified; Behavior, Animal; Chromatography, High Pressure Liquid; Conditioning, Psychological; Disease Models, Animal; Dopamine; Drosophila; Drosophila Proteins; Electric Stimulation; Ethanol; Food Preferences; Green Fluorescent Proteins; Male; Maze Learning; Mushroom Bodies; Neurons; Odorants; Reward; Synaptic Transmission; Time Factors; Tyrosine 3-Monooxygenase

2011
Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats.
    Brain research bulletin, 2012, Jun-01, Volume: 88, Issue:2-3

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Choice Behavior; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Impulsive Behavior; Male; Rats; Reinforcement, Psychology; Reward

2012
Conditioned place preference studies with atomoxetine in an animal model of ADHD: effects of previous atomoxetine treatment.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Animals; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Propylamines; Rats; Reward

2011
Timing behavior in streptozotocin-induced diabetic rats.
    Behavioural brain research, 2011, Oct-10, Volume: 224, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Blood Glucose; Choice Behavior; Conditioning, Operant; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Maze Learning; Neuropsychological Tests; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Reward; Time Perception

2011
A critical threshold of rehabilitation involving brain-derived neurotrophic factor is required for poststroke recovery.
    Neurorehabilitation and neural repair, 2011, Volume: 25, Issue:8

    Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Exercise Therapy; Functional Laterality; Infarction, Middle Cerebral Artery; Locomotion; Male; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Recovery of Function; Reward

2011
α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jul-27, Volume: 31, Issue:30

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Body Temperature; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Agonists; Protein Binding; Pyridines; Receptors, Nicotinic; Reward; Synaptosomes; Tritium

2011
4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Administration, Oral; Animals; Central Nervous System Stimulants; Corpus Striatum; Designer Drugs; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Hippocampus; Male; Methamphetamine; Public Health; Rats; Rats, Sprague-Dawley; Reward; Serotonin

2011
Identification of a dopamine receptor-mediated opiate reward memory switch in the basolateral amygdala-nucleus accumbens circuit.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Aug-03, Volume: 31, Issue:31

    Topics: Action Potentials; Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Benzazepines; Conditioning, Operant; Cyclic AMP; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Memory; Morphine; Nucleus Accumbens; Opioid-Related Disorders; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Opioid; Reward; Salicylamides; Thionucleotides

2011
"Liking" and "wanting" of sweet and oily food stimuli as affected by high-fat diet-induced obesity, weight loss, leptin, and genetic predisposition.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:5

    Topics: Adiposity; Animals; Caloric Restriction; Corn Oil; Dietary Fats; Disease Models, Animal; Feeding Behavior; Food Preferences; Genetic Predisposition to Disease; Leptin; Male; Motivation; Obesity; Phenotype; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Sucrose; Taste; Weight Loss

2011
The missing variable: ultrasonic vocalizations reveal hidden sensitization and tolerance-like effects during long-term cocaine administration.
    Psychopharmacology, 2012, Volume: 219, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Drug Tolerance; Extinction, Psychological; Locomotion; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Ultrasonics; Vocalization, Animal

2012
Reward and relapse: complete gene-induced dissociation in an animal model of alcohol dependence.
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:3

    Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Catalase; Cues; Disease Models, Animal; Ethanol; Genetic Vectors; Humans; Lentivirus; Microinjections; Quinine; Rats; Rats, Wistar; Reward; RNA, Small Interfering; Secondary Prevention; Self Administration; Ventral Tegmental Area

2012
Rewarding electrical brain stimulation in rats after peripheral nerve injury: decreased facilitation by commonly abused prescription opioids.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Adenosine; Amines; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hydromorphone; Injections, Spinal; Male; Methadone; Oxycodone; Peripheral Nerve Injuries; Rats; Rats, Inbred F344; Reward

2011
Superior colliculus lesions impair threat responsiveness in infant capuchin monkeys.
    Neuroscience letters, 2011, Oct-31, Volume: 504, Issue:3

    Topics: Animals; Cebus; Conflict, Psychological; Disease Models, Animal; Escape Reaction; Fear; Feeding Behavior; Humans; Ibotenic Acid; Inhibition, Psychological; Instillation, Drug; Kluver-Bucy Syndrome; Neurotoxins; Pattern Recognition, Visual; Reaction Time; Reward; Snakes; Superior Colliculi

2011
A translational behavioral model of mood-based impulsivity: Implications for substance abuse.
    Drug and alcohol dependence, 2012, Apr-01, Volume: 122, Issue:1-2

    Topics: Adolescent; Adult; Affect; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Female; Humans; Impulsive Behavior; Male; Rats; Reward; Self Administration; Substance-Related Disorders; Surveys and Questionnaires; Translational Research, Biomedical

2012
Behavioural and physiological correlates of impulsivity in the domestic dog (Canis familiaris).
    Physiology & behavior, 2012, Feb-01, Volume: 105, Issue:3

    Topics: Aggression; Animals; Choice Behavior; Chromatography, High Pressure Liquid; Conditioning, Operant; Disease Models, Animal; Dogs; Dopamine; Exploratory Behavior; Homovanillic Acid; Hydroxyindoleacetic Acid; Impulsive Behavior; Reinforcement Schedule; Reward; Serotonin; Statistics, Nonparametric; Time Factors

2012
Olanzapine suppresses the rewarding and discriminative stimulus effects induced by morphine.
    Synapse (New York, N.Y.), 2012, Volume: 66, Issue:2

    Topics: Analgesics, Opioid; Animals; Antipsychotic Agents; Benzodiazepines; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Morphine; Olanzapine; Opioid-Related Disorders; Rats; Rats, Inbred F344; Reward

2012
Rodent models of adaptive decision making.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 829

    Topics: Adaptation, Psychological; Animals; Attention; Decision Making; Disease Models, Animal; Mental Disorders; Physical Exertion; Rats; Reward; Substance-Related Disorders

2012
Operant model of frustrated expected reward in mice.
    Addiction biology, 2012, Volume: 17, Issue:4

    Topics: Aggression; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Eating; Extinction, Psychological; Frustration; Male; Mice; Mice, Inbred C57BL; Reinforcement Schedule; Reward; Self Administration

2012
Lesions of the thalamic reuniens cause impulsive but not compulsive responses.
    Brain structure & function, 2013, Volume: 218, Issue:1

    Topics: Animals; Attention; Behavior, Animal; Choice Behavior; Compulsive Behavior; Disease Models, Animal; Habituation, Psychophysiologic; Impulsive Behavior; Inhibition, Psychological; Male; Midline Thalamic Nuclei; Motivation; Motor Activity; N-Methylaspartate; Neurotoxicity Syndromes; Rats; Rats, Long-Evans; Reaction Time; Reward; Time Factors

2013
mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Alcoholism; Amygdala; Animals; Behavior, Animal; Cues; Disease Models, Animal; Ethanol; Extinction, Psychological; Male; Microinjections; Nucleus Accumbens; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Self Administration; Sucrose; Thiazoles

2012
Ethanol exposure during either adolescence or adulthood alters the rewarding effects of cocaine in adult rats.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley; Reward

2012
Feeding and reward: ontogenetic changes in an animal model of obesity.
    Neuropharmacology, 2012, Volume: 62, Issue:8

    Topics: Animals; Body Weight; Disease Models, Animal; Eating; Feeding Behavior; Hyperphagia; Nucleus Accumbens; Obesity; Rats; Rats, Inbred OLETF; Receptor, Cholecystokinin A; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward

2012
Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:7

    Topics: Animals; Behavior, Animal; Caloric Restriction; Disease Models, Animal; Mice; Mice, Transgenic; Motivation; Receptors, Dopamine D2; Reward; Schizophrenia; Schizophrenic Psychology; Sucrose

2012
Differential behavioral responses of the spontaneously hypertensive rat to methylphenidate and methamphetamine: lack of a rewarding effect of repeated methylphenidate treatment.
    Neuroscience letters, 2012, Apr-18, Volume: 514, Issue:2

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Psychological; Disease Models, Animal; Male; Methamphetamine; Methylphenidate; Rats; Rats, Inbred SHR; Rats, Wistar; Reward

2012
Novel use of a lipid-lowering fibrate medication to prevent nicotine reward and relapse: preclinical findings.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:8

    Topics: Action Potentials; Animals; Clofibrate; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Hypolipidemic Agents; Indoles; Male; Neurons; Nicotine; Nucleus Accumbens; PPAR alpha; Rats; Rats, Sprague-Dawley; Reward; Saimiri; Secondary Prevention; Self Administration; Tobacco Use Disorder; Ventral Tegmental Area

2012
Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry.
    International journal of obesity (2005), 2013, Volume: 37, Issue:3

    Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Diet, High-Fat; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neuronal Plasticity; Obesity; Promoter Regions, Genetic; Receptors, Dopamine D2; Reward; Stress, Psychological; Swimming

2013
Pramipexole- and methamphetamine-induced reward-mediated behavior in a rodent model of Parkinson's disease and controls.
    Behavioural brain research, 2012, Jul-15, Volume: 233, Issue:1

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Association Learning; Benzothiazoles; Conditioning, Operant; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Forelimb; Male; Methamphetamine; Motor Activity; Nucleus Accumbens; Oxidopamine; Parkinson Disease; Pramipexole; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reward; Tyrosine 3-Monooxygenase

2012
Assessment of chronic trigeminal neuropathic pain by the orofacial operant test in rats.
    Behavioural brain research, 2012, Sep-01, Volume: 234, Issue:1

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Chronic Pain; Cold Temperature; Disease Models, Animal; Facial Pain; Hyperalgesia; Male; Morphine; Neuralgia; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reward; Trigeminal Nerve Diseases

2012
Evaluation of an Aβ(1-40)-induced cognitive deficit in rat using a reward-directed instrumental learning task.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Cognition Disorders; Conditioning, Operant; Discrimination, Psychological; Disease Models, Animal; Extinction, Psychological; Male; Neurotransmitter Agents; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Reaction Time; Reinforcement Schedule; Reward

2012
The monoamine stabilizer (-)-OSU6162 attenuates voluntary ethanol intake and ethanol-induced dopamine output in nucleus accumbens.
    Biological psychiatry, 2012, Nov-15, Volume: 72, Issue:10

    Topics: Alcohol Drinking; Animals; Behavioral Symptoms; Cues; Disease Models, Animal; Dopamine; Drug Discovery; Ethanol; Male; Microdialysis; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Piperidines; Rats; Reward; Secondary Prevention; Substance Withdrawal Syndrome

2012
The atypical antidepressant mirtazapine attenuates expression of morphine-induced place preference and motor sensitization.
    Brain research, 2012, Sep-07, Volume: 1472

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Conditioning, Operant; Cues; Disease Models, Animal; Male; Mianserin; Mirtazapine; Morphine; Morphine Dependence; Motor Activity; Rats; Rats, Sprague-Dawley; Reward

2012
Distance from source of reward as a marker for extinction-induced "despair": modulation by the antidepressants clomipramine and citalopram.
    Neuroscience, 2012, Oct-25, Volume: 223

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Clomipramine; Conditioning, Operant; Depressive Disorder, Major; Disease Models, Animal; Exploratory Behavior; Extinction, Psychological; Male; Rats; Rats, Wistar; Reaction Time; Reward; Time Factors

2012
Effect of σ₁ receptor antagonism on ethanol and natural reward seeking.
    Neuroreport, 2012, Oct-03, Volume: 23, Issue:14

    Topics: Alcoholism; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Ethanol; Extinction, Psychological; Male; Rats; Rats, Wistar; Receptors, sigma; Reward

2012
Acetylcholine facilitates recovery of episodic memory after brain damage.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Oct-03, Volume: 32, Issue:40

    Topics: Acetylcholine; Alzheimer Disease; Amnesia; Animals; Brain Damage, Chronic; Cholinergic Fibers; Disease Models, Animal; Female; Fornix, Brain; Macaca fascicularis; Macaca mulatta; Male; Mammillary Bodies; Memory, Episodic; Neuronal Plasticity; Pattern Recognition, Visual; Psychomotor Performance; Reward; Temporal Lobe

2012
Enhanced reward-facilitating effects of d-amphetamine in rats in the quinpirole model of obsessive-compulsive disorder.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:5

    Topics: Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Disease Models, Animal; Dopamine Antagonists; Electric Stimulation; Haloperidol; Male; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Wistar; Reward; Self Administration

2013
GLP-1 analog attenuates cocaine reward.
    Molecular psychiatry, 2013, Volume: 18, Issue:9

    Topics: Animals; Brain; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Exenatide; Exploratory Behavior; Glucagon-Like Peptide 1; Male; Mice; Mice, Inbred C57BL; Peptides; Reward; Venoms

2013
Appetitive and consummative responding for liquid sucrose in the spontaneously hypertensive rat model of attention deficit hyperactivity disorder.
    Behavioural brain research, 2013, Feb-01, Volume: 238

    Topics: Animals; Association Learning; Attention Deficit Disorder with Hyperactivity; Conditioning, Operant; Disease Models, Animal; Male; Motivation; Motor Activity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reward; Sucrose

2013
Pathway-specific dopaminergic deficits in a mouse model of Angelman syndrome.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:12

    Topics: Angelman Syndrome; Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Electric Stimulation; Female; Indoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Raclopride; Receptors, Dopamine D1; Reward; Self Stimulation; Substantia Nigra; Synaptic Transmission; Ubiquitin-Protein Ligases; Ventral Tegmental Area

2012
Diet-induced obesity: dopamine transporter function, impulsivity and motivation.
    International journal of obesity (2005), 2013, Volume: 37, Issue:8

    Topics: Animals; Blotting, Western; Body Weight; Diet, High-Fat; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Feeding Behavior; Impulsive Behavior; Male; Motivation; Obesity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reward; Signal Transduction

2013
A drug-paired taste cue elicits withdrawal and predicts cocaine self-administration.
    Behavioural brain research, 2013, Mar-01, Volume: 240

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taste

2013
Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Dec-11, Volume: 109, Issue:50

    Topics: Afferent Pathways; Anesthetics, Local; Animals; Disease Models, Animal; Dopamine Antagonists; Limbic System; Male; Models, Neurological; Nerve Block; Nucleus Accumbens; Pain; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Ventral Tegmental Area

2012
Lsamp⁻/⁻ mice display lower sensitivity to amphetamine and have elevated 5-HT turnover.
    Biochemical and biophysical research communications, 2013, Jan-04, Volume: 430, Issue:1

    Topics: Amphetamine; Animals; Cell Adhesion Molecules, Neuronal; Conditioning, Psychological; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Drug Resistance; Gene Expression; GPI-Linked Proteins; Mental Disorders; Mesencephalon; Mice; Mice, Knockout; Motor Activity; Reward; Serotonin; Social Behavior Disorders; Temporal Lobe

2013
Adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high-fat diet withdrawal.
    International journal of obesity (2005), 2013, Volume: 37, Issue:9

    Topics: Animals; Anxiety; Behavior, Animal; Blotting, Western; Brain; Brain-Derived Neurotrophic Factor; Diet, High-Fat; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neuronal Plasticity; Obesity; Promoter Regions, Genetic; Receptors, Corticotropin-Releasing Hormone; Reward; Stress, Psychological; Sucrose; Tyrosine 3-Monooxygenase

2013
Expression of HIV gp120 protein increases sensitivity to the rewarding properties of methamphetamine in mice.
    Addiction biology, 2014, Volume: 19, Issue:4

    Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Association Learning; Behavior, Animal; Central Nervous System Stimulants; Choice Behavior; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression; HIV Envelope Protein gp120; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Motivation; Quinine; Reward; Saccharin; Sex Distribution

2014
GDNF is a novel ethanol-responsive gene in the VTA: implications for the development and persistence of excessive drinking.
    Addiction biology, 2014, Volume: 19, Issue:4

    Topics: Alcohol Drinking; Alcohol-Related Disorders; Animals; Behavior, Animal; Blotting, Western; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Ethanol; Glial Cell Line-Derived Neurotrophic Factor; Male; Molecular Sequence Data; Nucleus Accumbens; Rats; Rats, Long-Evans; Real-Time Polymerase Chain Reaction; Reward; Self Administration; Ventral Tegmental Area

2014
The adenosine A2A receptor agonist CGS 21680 decreases ethanol self-administration in both non-dependent and dependent animals.
    Addiction biology, 2013, Volume: 18, Issue:5

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Alcoholism; Analysis of Variance; Animals; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Ethanol; Food Preferences; Male; Mice; Mice, Knockout; Motivation; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Reinforcement Schedule; Reward; Self Administration; Sucrose

2013
Suppression of the morphine-induced rewarding effect in the rat with neuropathic pain: implication of the reduction in mu-opioid receptor functions in the ventral tegmental area.
    Journal of neurochemistry, 2002, Volume: 82, Issue:5

    Topics: Animals; Behavior, Animal; Binding, Competitive; Disease Models, Animal; Dopamine; Extracellular Space; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Ligation; Male; Microdialysis; Morphine; Nucleus Accumbens; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Sciatic Neuropathy; Spatial Behavior; Ventral Tegmental Area

2002
Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:6

    Topics: Animals; Animals, Newborn; Behavior, Addictive; Cocaine-Related Disorders; Diagnosis, Dual (Psychiatry); Disease Models, Animal; Extinction, Psychological; Female; Hippocampus; Male; Motivation; Pregnancy; Rats; Rats, Sprague-Dawley; Reward; Schizophrenia; Self Administration

2002
Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Feb-01, Volume: 23, Issue:3

    Topics: Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine; Drug Administration Routes; Extinction, Psychological; Limbic System; Male; Nerve Growth Factor; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Substance Withdrawal Syndrome; Sucrose; Time; Ventral Tegmental Area

2003
Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens.
    Neuroscience, 2003, Volume: 118, Issue:1

    Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reward; Substance Withdrawal Syndrome; Synaptic Transmission

2003
Needed: mouse/human cross validation of reinstatement/relapse models (and drug reward models) to model human substance abuse vulnerability allelic variants.
    Psychopharmacology, 2003, Volume: 168, Issue:1-2

    Topics: Alleles; Animals; Disease Models, Animal; Genetic Variation; Humans; Mice; Models, Psychological; Reproducibility of Results; Reward; Secondary Prevention; Substance-Related Disorders

2003
Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents.
    Biological psychiatry, 2003, Jul-01, Volume: 54, Issue:1

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Central Nervous System Stimulants; Depression; Disease Models, Animal; Male; Mice; Rats; Rats, Wistar; Reward; Self Stimulation; Substance Withdrawal Syndrome; Swimming

2003
Evaluation of the effects of chronic mild stressors on hedonic and physiological responses: sex and strain compared.
    Brain research, 2003, Dec-05, Volume: 992, Issue:2

    Topics: Animals; Body Weight; Chronic Disease; Corticosterone; Depressive Disorder; Disease Models, Animal; Eating; Estrous Cycle; Female; Food Preferences; Male; Organ Size; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reward; Sex Factors; Species Specificity; Stress, Physiological; Sucrose

2003
A new primate model of focal stroke: endothelin-1-induced middle cerebral artery occlusion and reperfusion in the common marmoset.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2004, Volume: 24, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Callithrix; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Epoxy Resins; Female; Forelimb; Hand Strength; Hindlimb; Infarction, Middle Cerebral Artery; Male; Perfusion; Phthalic Anhydrides; Physical Stimulation; Pilot Projects; Reflex; Reperfusion Injury; Reward; Stroke; Vocalization, Animal

2004
Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Mar-03, Volume: 24, Issue:9

    Topics: Animals; Antigens, CD; Corpus Striatum; Discrimination Learning; Disease Models, Animal; Dopamine; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Microinjections; Motor Activity; Neurotoxicity Syndromes; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Reward; RNA, Messenger; Spatial Behavior; Substance-Related Disorders; Tumor Necrosis Factor-alpha

2004
Role of extracellular signal-regulated kinase in the ventral tegmental area in the suppression of the morphine-induced rewarding effect in mice with sciatic nerve ligation.
    Journal of neurochemistry, 2004, Volume: 88, Issue:6

    Topics: Analgesics, Opioid; Animals; Cytosol; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Ligation; Male; Mesencephalon; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Morphine; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Opioid, mu; Reward; Sciatic Neuropathy; Signal Transduction; Spatial Behavior; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2004
Dose-specific effects of scopolamine on canine cognition: impairment of visuospatial memory, but not visuospatial discrimination.
    Psychopharmacology, 2004, Volume: 175, Issue:1

    Topics: Aging; Animals; Behavior, Animal; Discrimination Learning; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Memory Disorders; Muscarinic Antagonists; Reward; Scopolamine; Vision Disorders

2004
Dissociation of hemi-spatial and hemi-motor impairments in a unilateral primate model of Parkinson's disease.
    Behavioural brain research, 2004, Apr-02, Volume: 150, Issue:1-2

    Topics: Animals; Callithrix; Conditioning, Operant; Disease Models, Animal; Dopamine; Female; Functional Laterality; Head Movements; Image Processing, Computer-Assisted; Male; Motor Activity; Neostriatum; Oxidopamine; Parkinson Disease; Reward; Rotation; Space Perception; Substantia Nigra; Sympathectomy, Chemical; Sympatholytics; Tyrosine 3-Monooxygenase

2004
Low dose of heroin inhibits drug-seeking elicited by cues after prolonged withdrawal from heroin self-administration in rats.
    Neuroreport, 2004, Mar-22, Volume: 15, Issue:4

    Topics: Animals; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Heroin; Heroin Dependence; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Risk Factors; Self Administration; Substance Withdrawal Syndrome; Time Factors

2004
Subchronic phencyclidine treatment impairs performance of C57BL/6 mice in the attentional set-shifting task.
    Behavioural pharmacology, 2004, Volume: 15, Issue:2

    Topics: Animals; Attention; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Feeding Behavior; Hallucinogens; Male; Mice; Mice, Inbred C57BL; Motor Activity; Odorants; Phencyclidine; Reward; Schizophrenic Psychology

2004
Implication of spinal protein kinase C in the suppression of morphine-induced rewarding effect under a neuropathic pain-like state in mice.
    Neuroscience, 2004, Volume: 125, Issue:3

    Topics: Analgesics, Opioid; Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Indoles; Ligation; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Neuralgia; Protein Kinase C; Pyrroles; Reward; Sciatic Neuropathy; Spinal Cord; Up-Regulation

2004
Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:4

    Topics: Acetaldehyde; Adolescent; Age Factors; Aging; Animals; Brain; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Nicotiana; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder

2005
Androgen dependence in hamsters: overdose, tolerance, and potential opioidergic mechanisms.
    Neuroscience, 2005, Volume: 130, Issue:4

    Topics: Anabolic Agents; Androgens; Animals; Autonomic Nervous System; Autonomic Nervous System Diseases; Brain; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Drug Tolerance; Female; Gait Disorders, Neurologic; Male; Mesocricetus; Mortality; Narcotic Antagonists; Neural Pathways; Opioid Peptides; Respiratory Insufficiency; Reward; Self Administration; Substance-Related Disorders; Testosterone

2005
Effects of chronic mild stress on sexual behavior, locomotor activity and consumption of sucrose and saccharine solutions.
    Physiology & behavior, 2005, Mar-31, Volume: 84, Issue:4

    Topics: Analysis of Variance; Animals; Chronic Disease; Depression; Disease Models, Animal; Drinking Behavior; Exploratory Behavior; Female; Food Preferences; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sexual Behavior, Animal; Stress, Psychological; Sucrose; Taste

2005
Abnormal patterns of maternal behavior in a genetic animal model of depression.
    Physiology & behavior, 2005, Mar-31, Volume: 84, Issue:4

    Topics: Analysis of Variance; Animals; Appetitive Behavior; Depressive Disorder; Disease Models, Animal; Female; Maternal Behavior; Postpartum Period; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Reward

2005
Repeated 2 Hz peripheral electrical stimulations suppress morphine-induced CPP and improve spatial memory ability in rats.
    Experimental neurology, 2005, Volume: 194, Issue:2

    Topics: Animals; Brain; Conditioning, Psychological; Disease Models, Animal; Electroacupuncture; Male; Maze Learning; Memory Disorders; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Sprague-Dawley; Recovery of Function; Reward; Substance Withdrawal Syndrome; Treatment Outcome

2005
Implication of cyclin-dependent kinase 5 in the development of psychological dependence on and behavioral sensitization to morphine.
    Journal of neurochemistry, 2005, Volume: 93, Issue:6

    Topics: Animals; Behavior, Animal; Brain Chemistry; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Gyrus Cinguli; Male; Mice; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Neuronal Plasticity; Phosphorylation; Purines; Reward; Roscovitine; Up-Regulation

2005
Effect of operant self-administration of 10% ethanol plus 10% sucrose on dopamine and ethanol concentrations in the nucleus accumbens.
    Journal of neurochemistry, 2005, Volume: 93, Issue:6

    Topics: Alcoholism; Animals; Brain Chemistry; Calcium Signaling; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Eating; Ethanol; Extracellular Fluid; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Long-Evans; Reaction Time; Reward; Self Administration; Sucrose

2005
Periadolescent nicotine administration produces enduring changes in dendritic morphology of medium spiny neurons from nucleus accumbens.
    Neuroscience letters, 2005, Sep-09, Volume: 385, Issue:2

    Topics: Age Factors; Animals; Cell Shape; Dendrites; Disease Models, Animal; Male; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Risk Factors; Sexual Maturation; Tobacco Use Disorder

2005
Lesions to the subthalamic nucleus decrease impulsive choice but impair autoshaping in rats: the importance of the basal ganglia in Pavlovian conditioning and impulse control.
    The European journal of neuroscience, 2005, Volume: 21, Issue:11

    Topics: Animals; Attention; Basal Ganglia; Basal Ganglia Diseases; Choice Behavior; Cognition; Cognition Disorders; Conditioning, Classical; Denervation; Disease Models, Animal; Impulsive Behavior; Male; Neural Pathways; Neuropsychological Tests; Prefrontal Cortex; Rats; Reward; Subthalamic Nucleus

2005
Antidepressant-like effects of BCEF0083 in the chronic unpredictable stress models in mice.
    Chinese medical journal, 2005, Jun-05, Volume: 118, Issue:11

    Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Body Weight; Chronic Disease; Depression; Disease Models, Animal; Escape Reaction; Fungi; Male; Mice; Reward

2005
Conditioned nicotine withdrawal profoundly decreases the activity of brain reward systems.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jun-29, Volume: 25, Issue:26

    Topics: Animals; Brain; Disease Models, Animal; Male; Nicotine; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders

2005
Reward and anxiety in genetic animal models of childhood depression.
    Behavioural brain research, 2005, Oct-14, Volume: 164, Issue:1

    Topics: Age Factors; Analysis of Variance; Animals; Anxiety; Child; Conditioning, Classical; Depressive Disorder, Major; Disease Models, Animal; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Humans; Male; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar; Reward; Sexual Maturation; Social Behavior; Species Specificity; Stress, Psychological; Taste

2005
The lack of A2A adenosine receptors diminishes the reinforcing efficacy of cocaine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:5

    Topics: Adenosine; Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Male; Mice; Mice, Knockout; Motor Activity; Receptor, Adenosine A2A; Reinforcement, Psychology; Reward; Self Administration

2006
Decreased sensitivity to the effects of dopamine D1-like, but not D2-like, receptor antagonism in the posterior hypothalamic region/anterior ventral tegmental area on brain reward function during chronic exposure to nicotine in rats.
    Brain research, 2005, Oct-05, Volume: 1058, Issue:1-2

    Topics: Animals; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Drug Administration Schedule; Drug Tolerance; Hypothalamus, Posterior; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder; Ventral Tegmental Area

2005
Environment makes amphetamine-induced dopamine release in the nucleus accumbens totally impulse-dependent.
    Synapse (New York, N.Y.), 2005, Dec-01, Volume: 58, Issue:3

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Environment; Extracellular Fluid; Food Deprivation; Genetic Predisposition to Disease; Genotype; Impulsive Behavior; Male; Mice; Mice, Inbred DBA; Microdialysis; Nucleus Accumbens; Reward; Sodium Channel Blockers; Synaptic Transmission; Time Factors

2005
Preexposure during or following adolescence differently affects nicotine-rewarding properties in adult rats.
    Psychopharmacology, 2006, Volume: 184, Issue:3-4

    Topics: Age Factors; Animals; Arousal; Association Learning; Choice Behavior; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Injections, Intraperitoneal; Male; Motor Activity; Nicotine; Premedication; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Social Environment; Tobacco Use Disorder

2006
Genetic identification of AChE as a positive modulator of addiction to the psychostimulant D-amphetamine in zebrafish.
    Journal of neurobiology, 2006, Volume: 66, Issue:5

    Topics: Acetylcholine; Acetylcholinesterase; Amphetamine-Related Disorders; Animals; Biological Evolution; Brain; Brain Chemistry; Central Nervous System Stimulants; Cholinergic Fibers; Cholinesterase Inhibitors; Conditioning, Psychological; Dextroamphetamine; Disease Models, Animal; Dopamine; Female; Male; Mutation; Reward; Zebrafish

2006
AMPA-receptor GluR1 subunits are involved in the control over behavior by cocaine-paired cues.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Glutamic Acid; Learning; Male; Mice; Mice, Knockout; Reaction Time; Receptors, AMPA; Reinforcement, Psychology; Reward; Self Administration; Synaptic Transmission

2007
Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Behavior, Addictive; Brain; Chronic Disease; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperkinesis; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration; Substance Withdrawal Syndrome

2007
Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-22, Volume: 26, Issue:12

    Topics: alpha-Methyltyrosine; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Medial Forebrain Bundle; Mice; Mice, Knockout; Neostriatum; Presynaptic Terminals; Reward; Synapsins; Synaptic Transmission; Synaptic Vesicles; Up-Regulation; Ventral Tegmental Area

2006
Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-22, Volume: 26, Issue:12

    Topics: Animals; Anxiety Disorders; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Organ Culture Techniques; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Septal Nuclei; Stress, Psychological; Synaptic Transmission

2006
Elevation of glucocorticoids is necessary but not sufficient for the escalation of cocaine self-administration by chronic electric footshock stress in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroshock; Male; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Stress, Psychological; Up-Regulation

2007
Acute and repeated cocaine induces alterations in FosB/DeltaFosB expression in the paraventricular nucleus of the hypothalamus.
    Brain research, 2006, May-23, Volume: 1090, Issue:1

    Topics: Adaptation, Physiological; Animals; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hypothalamo-Hypophyseal System; Male; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine; Reward; Transcriptional Activation; Up-Regulation

2006
Tryptophan-deficient diet increases the neurochemical and behavioral response to amphetamine.
    Brain research, 2006, Jun-13, Volume: 1094, Issue:1

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Brain; Brain Chemistry; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Extracellular Fluid; Food, Formulated; Hydroxyindoleacetic Acid; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Serotonin; Tryptophan

2006
Conditioned withdrawal drives heroin consumption and decreases reward sensitivity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, May-31, Volume: 26, Issue:22

    Topics: Animals; Conditioning, Classical; Disease Models, Animal; Electric Stimulation; Heroin; Heroin Dependence; Male; Naloxone; Narcotic Antagonists; Rats; Reward; Self Stimulation; Substance Withdrawal Syndrome

2006
Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice.
    Brain research, 2006, Jun-13, Volume: 1094, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Brain; Central Nervous System Depressants; Conditioning, Psychological; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Ethanol; Finasteride; Male; Mice; Mice, Inbred DBA; Motor Activity; Pregnanolone; Progesterone; Proto-Oncogene Proteins c-fos; Reward; Ventral Tegmental Area

2006
Animal models/tests of drug addiction: a quest for the holy grail, or the pursuit of wild geese?
    Addiction biology, 2006, Volume: 11, Issue:1

    Topics: Alcoholism; Animals; Conditioning, Psychological; Disease Models, Animal; Motivation; Reward; Rodentia; Substance Withdrawal Syndrome; Substance-Related Disorders

2006
Ethanol activates cAMP response element-mediated gene expression in select regions of the mouse brain.
    Brain research, 2006, Aug-23, Volume: 1106, Issue:1

    Topics: Alcohol-Induced Disorders, Nervous System; Animals; Brain; Brain Chemistry; Central Nervous System Depressants; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Ethanol; Female; Galactosides; Gene Expression Regulation; Genes, Reporter; Indoles; Lac Operon; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reward; RNA, Messenger; Signal Transduction

2006
The effects of temporary inactivation of the orbital cortex in the signal attenuation rat model of obsessive compulsive disorder.
    Behavioral neuroscience, 2006, Volume: 120, Issue:4

    Topics: Analysis of Variance; Animals; Behavior, Animal; Conditioning, Classical; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Frontal Lobe; Male; Obsessive-Compulsive Disorder; Rats; Rats, Wistar; Reward

2006
An endogenous neuroprotectant substance, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), prevents the behavioral and neurochemical effects of cocaine reinstatement in drug-dependent rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Limbic System; Male; Neural Pathways; Neuroprotective Agents; Norepinephrine; Rats; Reward; Secondary Prevention; Self Administration; Serotonin; Substance Withdrawal Syndrome; Tetrahydroisoquinolines; Ventral Tegmental Area

2007
Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens.
    Hippocampus, 2006, Volume: 16, Issue:10

    Topics: Animals; Conditioning, Psychological; Cues; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Hippocampus; Hormone Antagonists; Male; Memory; Mifepristone; Morphine; Morphine Dependence; Motivation; Narcotics; Nerve Net; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward; Solvents

2006
Heroin addiction: anticipating the reward of heroin or the agony of withdrawal?
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-06, Volume: 26, Issue:36

    Topics: Animals; Conditioning, Classical; Disease Models, Animal; Electric Stimulation; Heroin; Heroin Dependence; Male; Naloxone; Narcotic Antagonists; Rats; Reward; Self Stimulation; Substance Withdrawal Syndrome

2006
Peroxisome proliferator-activated receptor gamma activation relieves expression of behavioral sensitization to methamphetamine in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:5

    Topics: Amphetamine-Related Disorders; Anilides; Animals; Behavior, Animal; Brain; Brain Chemistry; Cell Nucleus; Disease Models, Animal; Dopamine Uptake Inhibitors; Electrophoretic Mobility Shift Assay; Encephalitis; Hypoglycemic Agents; Male; Methamphetamine; Mice; Mice, Inbred ICR; Motor Activity; Nucleus Accumbens; Pioglitazone; PPAR gamma; Psychoses, Substance-Induced; Retinoid X Receptors; Reward; Thiazolidinediones

2007
Biphasic alterations in serotonin-1B (5-HT1B) receptor function during abstinence from extended cocaine self-administration.
    Journal of neurochemistry, 2006, Volume: 99, Issue:5

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Motor Activity; Neural Pathways; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Reward; Self Administration; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area

2006
Context-dependent prefrontal cortex regulation of cocaine self-administration and reinstatement behaviors in rats.
    The European journal of neuroscience, 2006, Volume: 24, Issue:11

    Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Environment, Controlled; Lidocaine; Male; Neural Pathways; Odorants; Photic Stimulation; Prefrontal Cortex; Rats; Reward; Self Administration

2006
Evaluation of reward processes in an animal model of depression.
    Psychopharmacology, 2007, Volume: 190, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Cocaine; Depression; Disease Models, Animal; Electric Stimulation; Exploratory Behavior; Food Preferences; Locomotion; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Self Stimulation; Sensory Thresholds; Sucrose; Time Factors

2007
The effects of buprenorphine on fentanyl withdrawal in rats.
    Psychopharmacology, 2007, Volume: 191, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Emotions; Fentanyl; Male; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar; Receptors, Opioid, mu; Reward; Substance Withdrawal Syndrome; Time Factors

2007
Morphine-induced place conditioning in Fischer and Lewis rats: acquisition and dose-response in a fully biased procedure.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:3

    Topics: Animals; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Morphine; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reward; Species Specificity; Substance-Related Disorders

2007
Differential effects of acute and subchronic clozapine and haloperidol on phencyclidine-induced decreases in voluntary sucrose consumption in rats.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:3

    Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Eating; Hallucinogens; Haloperidol; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Reward; Schizophrenia; Sucrose

2007
Further genetic characterization of the fawn-hooded (FH/Wjd) rat, an animal model of comorbid depression and alcoholism.
    Psychiatric genetics, 2007, Volume: 17, Issue:2

    Topics: Alcoholism; Animals; Comorbidity; Depressive Disorder; Disease Models, Animal; Female; Hair Color; Male; Rats; Rats, Mutant Strains; Reward

2007
Compulsive drug seeking by rats under punishment: effects of drug taking history.
    Psychopharmacology, 2007, Volume: 194, Issue:1

    Topics: Anesthetics, Local; Animals; Animals, Outbred Strains; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Electroshock; Fear; Feeding Behavior; Male; Punishment; Rats; Reinforcement Schedule; Reward; Self Administration; Solutions; Sucrose; Time Factors

2007
Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats.
    Biological psychiatry, 2008, Feb-01, Volume: 63, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Impulsive Behavior; Male; Nicotine; Predictive Value of Tests; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration; Substance-Related Disorders

2008
Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats.
    Neuropharmacology, 2007, Volume: 53, Issue:6

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Berberine Alkaloids; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration; Stereoisomerism

2007
The reward system and maternal behavior in an animal model of depression: a microdialysis study.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Depressive Disorder; Dialysis Solutions; Disease Models, Animal; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Maternal Behavior; Microdialysis; Nucleus Accumbens; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Reward; Serotonin

2008
Increased rewarding properties of morphine in perinatally protein-malnourished rats.
    Neuroscience, 2007, Dec-05, Volume: 150, Issue:2

    Topics: Amygdala; Animals; Brain; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fetal Nutrition Disorders; Limbic System; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Prefrontal Cortex; Pregnancy; Protein Deficiency; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reward; Up-Regulation

2007
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.
    Neuron, 2007, Nov-08, Volume: 56, Issue:3

    Topics: Acetylation; Adaptation, Physiological; Animals; Chromatin; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Emotions; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Histone Deacetylases; Histones; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Stress, Psychological

2007
Cocaine-conditioned place preference by dopamine-deficient mice is mediated by serotonin.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Nov-14, Volume: 27, Issue:46

    Topics: Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Fluoxetine; Male; Mice; Mice, Knockout; Mice, Transgenic; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission

2007
Differential effects of blockade of dopamine D1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and discrete cues.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Nov-14, Volume: 27, Issue:46

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Antagonists; Extinction, Psychological; Heroin Dependence; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Reward; Secondary Prevention; Self Administration

2007
Attenuation of cue-induced heroin-seeking behavior by cannabinoid CB1 antagonist infusions into the nucleus accumbens core and prefrontal cortex, but not basolateral amygdala.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:10

    Topics: Amygdala; Animals; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Heroin; Heroin Dependence; Male; Motivation; Narcotics; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Reward; Rimonabant

2008
Progesterone attenuates cocaine-induced conditioned place preference in female rats.
    Brain research, 2008, Jan-16, Volume: 1189

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Female; Learning; Memory Disorders; Menstrual Cycle; Neuropsychological Tests; Progesterone; Rats; Rats, Inbred F344; Recognition, Psychology; Recurrence; Reward; Sex Characteristics

2008
VTA dopamine neuron bursting is altered in an animal model of depression and corrected by desipramine.
    Journal of molecular neuroscience : MN, 2008, Volume: 34, Issue:3

    Topics: Action Potentials; Animals; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Disease Models, Animal; Dopamine; Fourier Analysis; Male; Motivation; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Reward; Signal Processing, Computer-Assisted; Synaptic Transmission; Treatment Outcome; Ventral Tegmental Area

2008
Upregulation of metabotropic glutamate receptor 8 mRNA expression in the rat forebrain after repeated amphetamine administration.
    Neuroscience letters, 2008, Mar-15, Volume: 433, Issue:3

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Gene Expression Regulation; Glutamic Acid; In Situ Hybridization; Injections, Intraperitoneal; Male; Nucleus Accumbens; Prosencephalon; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reward; RNA, Messenger; Synaptic Transmission; Time Factors; Up-Regulation

2008
Changed accumbal responsiveness to alcohol in rats pre-treated with nicotine or the cannabinoid receptor agonist WIN 55,212-2.
    Neuroscience letters, 2008, Mar-05, Volume: 433, Issue:1

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Analgesics; Animals; Benzoxazines; Cannabinoid Receptor Agonists; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Extracellular Fluid; Male; Microdialysis; Morpholines; Naphthalenes; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Reward; Up-Regulation

2008
Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Acetylation; Animals; Brain; Brain Chemistry; Brain-Derived Neurotrophic Factor; Chromatin Assembly and Disassembly; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Male; Mice; Mice, Inbred C57BL; Receptors, Dopamine D1; Reward; Signal Transduction; Synaptic Transmission; Tyrosine 3-Monooxygenase

2008
Direct evidence for the involvement of endogenous beta-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state.
    Neuroscience letters, 2008, Apr-25, Volume: 435, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; beta-Endorphin; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Knockout; Morphine; Narcotics; Pain Measurement; Protein Binding; Reaction Time; Reward; Sciatica; Time Factors; Tyrosine 3-Monooxygenase

2008
A study of remote spatial memory in aged rats.
    Neurobiology of aging, 2010, Volume: 31, Issue:1

    Topics: Aging; Animals; Disease Models, Animal; Environment, Controlled; Hippocampus; Learning; Male; Memory; Memory Disorders; Neuropsychological Tests; Orientation; Rats; Rats, Long-Evans; Reward; Space Perception

2010
Pharmacological validation of a chronic social stress model of depression in rats: effects of reboxetine, haloperidol and diazepam.
    Behavioural pharmacology, 2008, Volume: 19, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Depression; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Male; Morpholines; Motivation; Motor Activity; Rats; Rats, Wistar; Reboxetine; Reward; Stress, Psychological

2008
Amphetamine enhancement of reward asymmetry.
    Psychopharmacology, 1981, Volume: 73, Issue:4

    Topics: Amphetamine; Animals; Choice Behavior; Disease Models, Animal; Dopamine; Functional Laterality; Humans; Male; Rats; Reward; Schizophrenia; Self Stimulation

1981
Chronic mild stress and sucrose consumption: validity as a model of depression.
    Physiology & behavior, 1996, Volume: 60, Issue:6

    Topics: Animals; Body Weight; Depressive Disorder; Disease Models, Animal; Drinking; Male; Rats; Reproducibility of Results; Reward; Stress, Physiological; Sucrose; Time Factors

1996
Elementary particles for models of drug dependence, 10th Okey Memorial Lecture presented at the Institute of Psychiatry, London on 19th March 1997.
    Drug and alcohol dependence, 1997, Dec-15, Volume: 48, Issue:3

    Topics: Animals; Behavior, Addictive; Brain; Cues; Discrimination, Psychological; Disease Models, Animal; Humans; Models, Psychological; Nicotine; Rats; Reward; Self Medication; Substance-Related Disorders; Terminology as Topic; Tobacco Use Disorder

1997
Elementary particles for models of drug dependence 10th Okey Memorial Lecture presented at the Institute of Psychiatry, London on 19th March 1997.
    Drug and alcohol dependence, 1998, Mar-01, Volume: 50, Issue:1

    Topics: Animals; Behavior, Addictive; Brain; Cues; Discrimination, Psychological; Disease Models, Animal; Humans; Models, Psychological; Nicotine; Rats; Reward; Self Medication; Substance-Related Disorders; Terminology as Topic; Tobacco Use Disorder

1998
Dramatic decreases in brain reward function during nicotine withdrawal.
    Nature, 1998, May-07, Volume: 393, Issue:6680

    Topics: Animals; Brain; Dihydro-beta-Erythroidine; Disease Models, Animal; Infusion Pumps, Implantable; Male; Motivation; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Reward; Self Stimulation; Sensory Thresholds; Substance Withdrawal Syndrome

1998
Intraaccumbens injections of substance P, morphine and amphetamine: effects on conditioned place preference and behavioral activity.
    Brain research, 1998, Apr-20, Volume: 790, Issue:1-2

    Topics: Acute Disease; Amphetamine; Animals; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Dopamine; Grooming; Locomotion; Male; Morphine; Morphine Dependence; Motivation; Narcotics; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Spatial Behavior; Substance P; Sympathomimetics

1998
Withdrawal of presession saccharin suppresses food-maintained responding in rats.
    Perceptual and motor skills, 1998, Volume: 86, Issue:2

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Drinking; Feeding Behavior; Food; Humans; Male; Rats; Reinforcement Schedule; Reward; Saccharin; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders; Water

1998
Dissociation of primary and secondary reward-relevant limbic nuclei in an animal model of relapse.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:5

    Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Infusion Pumps, Implantable; Limbic System; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration; Sodium Channels; Tetrodotoxin

2000
Dopamine D3 receptor agents as potential new medications for drug addiction.
    European psychiatry : the journal of the Association of European Psychiatrists, 2000, Volume: 15, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Locomotion; Naphthalenes; Neurons; Nucleus Accumbens; Pyrrolidines; Rats; Receptors, Dopamine; Reward

2000
Investigatory behavior of a novel conspecific by Wistar Kyoto, Wistar and Sprague-Dawley rats.
    Brain research bulletin, 2000, Volume: 53, Issue:6

    Topics: Animals; Depression; Disease Models, Animal; Exploratory Behavior; Female; Male; Memory; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar; Reward; Sexual Behavior, Animal; Stress, Physiological

2000
Animal models for the study of antidepressant activity.
    Brain research. Brain research protocols, 2001, Volume: 7, Issue:1

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Appetite; Behavior, Animal; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Escape Reaction; Fluoxetine; Imipramine; Male; Maze Learning; Phenelzine; Rats; Rats, Sprague-Dawley; Reward; Stress, Physiological; Time Factors

2001
Impulsive choice induced in rats by lesions of the nucleus accumbens core.
    Science (New York, N.Y.), 2001, Jun-29, Volume: 292, Issue:5526

    Topics: Animals; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Brain Mapping; Choice Behavior; Disease Models, Animal; Gyrus Cinguli; Impulsive Behavior; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Random Allocation; Rats; Reinforcement, Psychology; Reward

2001
Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:1

    Topics: Aminopyridines; Amphetamine; Amphetamine-Related Disorders; Animals; Body Weight; Brain; Depression; Disease Models, Animal; Drug Combinations; Electric Stimulation; Fluoxetine; Male; Mecamylamine; Neurons; Nicotine; Nicotinic Antagonists; Piperazines; Rats; Rats, Wistar; Reaction Time; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Substance Withdrawal Syndrome; Synaptic Transmission; Tobacco Use Disorder

2001
Hippocampal injections of amyloid beta-peptide 1-40 impair subsequent one-trial/day reward learning.
    Neurobiology of learning and memory, 2001, Volume: 76, Issue:2

    Topics: Alzheimer Disease; Animals; Carrier Proteins; Discrimination Learning; Disease Models, Animal; Gliosis; Hippocampus; Injections; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Retention, Psychology; Reward

2001
The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2001, Volume: 3, Issue:4

    Topics: Aconitine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Reward; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder

2001
Reduced TH-immunoreactive fibers in the limbic system of Sardinian alcohol-preferring rats.
    Brain research, 2002, Jan-11, Volume: 924, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Dopamine; Immunohistochemistry; Limbic System; Male; Nerve Fibers; Rats; Rats, Wistar; Reward; Tyrosine 3-Monooxygenase

2002
The effect of nitric oxide synthesis inhibition on intravenous cocaine self-administration.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:1

    Topics: Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Long-Evans; Reward; Self Administration

2002
Neurobiological evidence for hedonic allostasis associated with escalating cocaine use.
    Nature neuroscience, 2002, Volume: 5, Issue:7

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Administration Schedule; Drug Tolerance; Electric Stimulation; Electrodes, Implanted; Hypothalamus; Male; Rats; Rats, Wistar; Reaction Time; Regression Analysis; Reward; Self Administration; Sensory Thresholds

2002
Deficits in reward sensitivity in a neurodevelopmental rat model of schizophrenia.
    Psychopharmacology, 2002, Volume: 161, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Conditioning, Psychological; Disease Models, Animal; Female; Hippocampus; Ibotenic Acid; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Schizophrenia

2002
A reward-reduction model of depression using self stimulating rats: an appraisal.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:3

    Topics: Amphetamine; Animals; Depression; Disease Models, Animal; Humans; Imipramine; Male; Protriptyline; Rats; Reward; Self Stimulation

1979
Some behavioural signs of morphine withdrawal blocked by condition stimuli.
    Nature, 1975, May-29, Volume: 255, Issue:5507

    Topics: Animals; Behavior, Animal; Conditioning, Classical; Conflict, Psychological; Disease Models, Animal; Extinction, Psychological; Humans; Male; Morphine; Morphine Dependence; Naloxone; Punishment; Reinforcement Schedule; Reward; Substance Withdrawal Syndrome

1975
Human amnesia and animal models of amnesia: performance of amnesic patients on tests designed for the monkey.
    Behavioral neuroscience, 1988, Volume: 102, Issue:2

    Topics: Alcohol Amnestic Disorder; Amnesia; Animals; Attention; Discrimination Learning; Disease Models, Animal; Female; Haplorhini; Humans; Learning Disabilities; Male; Memory Disorders; Middle Aged; Reward; Verbal Learning

1988
Electrical stimulation of the brain as reinforcement of food consumption in aphagic cats.
    Experimental neurology, 1973, Volume: 40, Issue:1

    Topics: Animals; Brain; Cats; Conditioning, Psychological; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Feeding and Eating Disorders; Feeding Behavior; Female; Humans; Hypothalamus; Motivation; Reinforcement, Psychology; Reward; Self Stimulation; Septum Pellucidum; Tegmentum Mesencephali

1973
Brain theory and minimal brain dysfunction.
    Annals of the New York Academy of Sciences, 1973, Feb-28, Volume: 205

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Child; Conditioning, Operant; Disease Models, Animal; Dominance, Cerebral; Haplorhini; Humans; Reward

1973
Reactions to intrinsic and extrinsic rewards in protein-malnourished monkeys.
    Perceptual and motor skills, 1973, Volume: 36, Issue:3

    Topics: Animal Nutritional Physiological Phenomena; Animals; Dietary Proteins; Disease Models, Animal; Extinction, Psychological; Feeding Behavior; Haplorhini; Macaca; Nutrition Disorders; Problem Solving; Protein-Energy Malnutrition; Reinforcement Schedule; Reward

1973
Ethanol ingestion in the rat induced by rewarding brain stimulation.
    Physiology & behavior, 1972, Volume: 8, Issue:6

    Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Ethanol; Humans; Hypothalamus; Male; Osmolar Concentration; Rats; Reward; Self Stimulation; Solutions; Substance-Related Disorders; Sucrose; Taste; Water

1972
Differential reinforcement of latency (DRL) in phenylketonuric monkeys.
    Developmental psychobiology, 1970, Volume: 2, Issue:4

    Topics: Animals; Conditioning, Operant; Diet; Disease Models, Animal; Feeding Behavior; Female; Frustration; Haplorhini; Humans; Macaca; Phenylalanine; Phenylketonurias; Pregnancy; Reaction Time; Reinforcement, Psychology; Reward

1970