s,n,n'-tripropylthiocarbamate has been researched along with Addiction, Opioid in 172 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.91) | 18.7374 |
| 1990's | 8 (4.65) | 18.2507 |
| 2000's | 30 (17.44) | 29.6817 |
| 2010's | 87 (50.58) | 24.3611 |
| 2020's | 42 (24.42) | 2.80 |
| Authors | Studies |
|---|---|
| Cay, M; Kodele, S; Koob, GF; Schreiber, R; Upadhyay, J; Verrico, CD; Yammine, L | 1 |
| Proctor, SL | 1 |
| Huggett, SB; Ikeda, AS; Kaun, KR; McGeary, JE; Palmer, RHC | 1 |
| Brick, TR; Bunce, SC; Cleveland, HH; Deneke, E; Freet, CS; Knapp, KS; Petrie, DJ | 1 |
| Amgott-Kwan, AT; Zadina, JE | 1 |
| Browne, CJ; Cunningham, AM; Estill, M; Futamura, R; Godino, A; Hamilton, PJ; Hicks, EM; Huckins, LM; Hurd, YL; Martínez-Rivera, FJ; Minier-Toribio, A; Nestler, EJ; Parise, EM; Ramakrishnan, A; Shen, L; Torres-Berrío, A; Walker, DM | 1 |
| Bernat, EM; Donaldson, GW; Fix, ST; Froeliger, B; Garland, EL; Hanley, AW; Hudak, JP; Marchand, WR; Nakamura, Y | 1 |
| Liu, W; Wang, J; Yang, L | 1 |
| Hirai, T; Ide, S; Ikeda, K; Muto, T; Yamakawa, T | 1 |
| Koob, GF | 1 |
| Eikemo, M; Ernst, G; Garland, EL; Leknes, S; Trøstheim, M | 1 |
| Atchley, RM; Froeliger, B; Garland, EL; Hanley, AW; Zubieta, JK | 1 |
| Adelson, M; Kreek, MJ; Levran, O; Ott, J; Randesi, M; Rotrosen, J | 1 |
| Largent-Milnes, TM; Vanderah, TW; Zhang, H | 1 |
| May, AC; Paulus, MP; Stewart, JL | 1 |
| Baram, TZ; Bentzley, BS; Bolton, JL; Levis, SC; Mahler, SV; Molet, J; Perrone, CR | 1 |
| Lotfipour, S; Ren, M | 1 |
| Rodríguez Mega, E | 1 |
| Kyzer, JL; Wenthur, CJ | 1 |
| De Vries, TJ; Heinsbroek, JA; Peters, J | 1 |
| Haghparast, A; Hesam, S; Karimi, S; Karimi-Haghighi, S; Razavi, Y | 1 |
| Fu, J; Ge, S; Lang, B; Li, J; Li, N; Li, Y; Qu, L; Volkow, ND; Wang, GJ; Wang, J; Wang, P; Wang, X; Wang, Y; Wu, H; Zeng, J; Zhang, Y | 1 |
| Batho, A; Williams, ACC | 1 |
| Chalhoub, RM; Kalivas, PW | 1 |
| Freeman, KB; Pareek, T; Patel, TR; Prisinzano, TE; Schrock, HM; Williams, BC; Zamarripa, CA | 1 |
| Kreek, MJ; Windisch, KA | 1 |
| Baron, D; Blum, K; Bowirrat, A; Gold, MS | 1 |
| Fadda, P; Fattore, L; Fratta, W; Scherma, M | 1 |
| Fadda, P; Fattore, L; Fratta, W; Zanda, MT | 1 |
| Brewin, LW; Bryant, CD; Chen, MM; Coehlo, MA; Healy, AF; Lustig, E; Luttik, KP; Ruan, QT; Swancy, I; Szumlinski, KK; Tran, T; Yazdani, N | 1 |
| Garland, EL | 1 |
| Galaj, E; Xi, ZX | 1 |
| Alderete, JA; Cahill, CM; Evans, CJ; Kibaly, C; Law, PY; Liu, SH; Nasef, HS | 1 |
| Blendy, JA; Carpenter, MD; Heller, EA; Manners, MT | 1 |
| Borgland, SL; Mohammadkhani, A | 1 |
| Chen, J; Liu, J; Luo, J; Shao, Z; Tang, F; Wang, S; Yan, C; Yang, R; Yang, W; Yuan, K; Zhang, J | 1 |
| Fonville, L; Hayes, A; Herlinger, K; Hill, R; Lingford-Hughes, A; Nutt, D; Paterson, L | 1 |
| Agage, D; Epstein, DH; Finan, PH; Kowalczyk, WJ; Letzen, J; Mun, CJ; Phillips, KA; Pizzagalli, DA; Preston, KL; Stull, S | 1 |
| Leri, F; Limebeer, CL; Minhas, M; Parker, LA; Strom, E | 1 |
| Aupperle, RL; Ekhtiari, H; Kuplicki, R; Paulus, MP | 1 |
| Askalsky, P; Comer, SD; Jones, JD; Madera, G; Mogali, S | 1 |
| Hartmann, MC; Pleil, KE | 1 |
| Bailey, A; Georgiou, P; Kouimtsidis, C; Niforooshan, R; Robinson, F; Weber, C; Zanos, P | 1 |
| Babbs, RK; Bryant, CD; Goldberg, LR; Jenkins, DF; Johnson, WE; Kirkpatrick, SL; Lacki, OA; Luttik, KP; Yazdani, N | 1 |
| Laviolette, SR; Rosen, LG; Rushlow, WJ | 1 |
| Abé, C; Durazzo, TC; Guydish, J; Meyerhoff, DJ; Murray, DE; Murray, TA; Schmidt, TP | 1 |
| Beck, KD; Haber, P; Hogarth, L; Mahlberg, J; Morley, K; Moustafa, AA; Myers, CE; Weidemann, G | 1 |
| Dunn, KE; Finan, PH; Remeniuk, B | 1 |
| Ahmadi-Soleimani, SM; Azizi, H; Gompf, HS; Semnanian, S | 1 |
| Bouril, A; Elman, I; Fairchild, VP; Gur, RC; Langleben, DD; Lowen, SB; Shi, Z; Wang, AL | 1 |
| Service, RF | 1 |
| Hamed, A; Kursa, MB | 1 |
| Bonnet, U; Scherbaum, N | 2 |
| Haleem, DJ | 1 |
| Sewak, R; Spielholz, NI | 1 |
| Kreek, MJ; Liang, Y; Randesi, M; Yuferov, V; Zhang, Y; Zhao, C | 1 |
| Bossert, JM; Fredriksson, I; Lofaro, OM; Reiner, DJ; Shaham, Y | 1 |
| Pehrson, AL; Roberts, D; Sanchez, C; Wolfarth, A | 1 |
| Bilbo, SD; Gunn, M; Hanamsagar, R; Jo, YC; Kan, MJ; Rivera, PD; Stewart, D; Tran, PK | 1 |
| Haghparast, A; Karimi, S; Razavi, Y; Riahi, E; Zarrabian, S | 1 |
| Adelson, M; Levy-Gigi, E; Peles, E; Weiss, O | 1 |
| Carroll, KM; Potenza, MN; Scheinost, D; Yip, SW | 1 |
| Dong, P; Duan, S; He, XB; Jiang, P; Jin, S; Li, CY; Li, XM; Li, Y; Wu, ZH; Xi, W; Xu, FQ; Zhou, YD | 1 |
| Garami, J; Moustafa, AA | 1 |
| Andersen, JM; Bogen, IL; Boix, F; Kvello, AMS; Mørland, J | 1 |
| Kaye, AD; McAnally, H; Remillard, D | 1 |
| Eikemo, M; Kunøe, N; Leknes, S; Lobmaier, PP; Matziorinis, AM; Pedersen, ML; Sarfi, M | 1 |
| Bartuska, AD; Bell, RP; Daughters, SB; Dichter, GS; Reese, ED; Stein, JR; Yi, JY | 1 |
| Garland, EL; Hanley, AW; Moeller, SJ | 1 |
| Borsook, D; Elman, I | 1 |
| Hartzler, B; Rabun, C | 1 |
| Coscas, S; Karila, L; Lowenstein, W; Petit, A; Reynaud, M; Zarmdini, R | 1 |
| Chu Sin Chung, P; Kieffer, BL | 1 |
| Brooks, DJ; Lingford-Hughes, AR; Myers, JF; Nutt, DJ; Reid, AG; Stokes, PR; Taylor, LG; Turkheimer, FE; Watson, BJ; Wilson, SJ | 1 |
| Chen, W; Hong, Y; Ling, L; McLaughlin, MM; Xia, Y; Zou, X | 1 |
| Comer, SD; Cooper, ZD; Jones, JD; Kowalczyk, WJ; Manubay, JM; Metz, VE; Peyser, D; Saccone, PA; Smith, ME; Sullivan, MA; Vosburg, SK | 1 |
| Ahmad, T; Coolen, LM; de Jaeger, X; Lauzon, NM; Laviolette, SR; Lyons, D; Rosen, LG; Rushlow, W; Zunder, J | 1 |
| Anderson, BA; Faulkner, ML; Marvel, CL; Rilee, JJ; Yantis, S | 1 |
| Baldacchino, A; Balfour, D; Gradin, VB; Matthews, K; Steele, JD | 1 |
| Al-Khrasani, M; Fürst, Z; Riba, P | 1 |
| Guy, MD; Heinrichs, SC; Kaplan, GB; Kobrin, KL; Leite-Morris, KA; Young, AJ | 1 |
| Froeliger, B; Garland, EL; Howard, MO | 3 |
| Bartlett, C; Colucci, SV; Harris, SC; Perrino, PJ; Shram, M; Wang, Y | 1 |
| Aguiar, DC; Almeida-Santos, AF; Duarte, ID; Ferreira, RC; Gobira, PH; Moreira, FA; Romero, TR; Souza, DP | 1 |
| Grenald, SA; Largent-Milnes, TM; Vanderah, TW | 1 |
| Blanken, P; Booij, J; Bruijel, J; Goudriaan, AE; Hendriks, V; Koeter, MW; Kreek, MJ; van den Brink, W; van Ree, JM; Zaaijer, ER | 1 |
| Willyard, C | 1 |
| Balsdon, T; Beck, KD; Haber, P; Hogarth, L; Luzardo, A; Moustafa, AA; Myers, CE; Sheynin, J | 1 |
| Ayaz, H; Bunce, SC; Deneke, E; Harris, JD; Huhn, AS; Meyer, RE; Stankoski, DM | 1 |
| Chen, X; Nachtrab, G; Wienecke, CF; Zhu, Y | 1 |
| Edwards, RR; Johnson, MW; Johnson, PS; Smith, MT; Strain, EC; Tompkins, DA | 1 |
| Charles-Walsh, K; Hester, R; Upton, DJ | 1 |
| Chen, M; Cui, D; Lai, B; Ma, Q; Sheng, H; Song, J; Yang, L; Yuan, K; Zhang, W; Zheng, P | 1 |
| Beck, KD; Haber, P; Hogarth, L; Morley, K; Moustafa, AA; Myers, CE; Rego, J | 1 |
| Bryan, CJ; Froeliger, B; Garland, EL; Howard, MO; Nakamura, Y | 1 |
| Anastasio, NC; Comer, SD; Cunningham, KA; Fox, RG; Haney, M; Holliday, ED; Moeller, FG; Neelakantan, H; Stutz, SJ | 1 |
| Froeliger, B; Garland, EL; Howard, MO; Zubieta, JK | 1 |
| Badgaiyan, RD; Baron, D; Blum, K; Demetrovics, Z; Dushaj, K; Febo, M; Gold, MS; Jacobs, W; McCall, WV | 1 |
| Booij, J; Franken, IH; van den Brink, W; Veltman, DJ; Zijlstra, F | 1 |
| Craft, RM | 1 |
| Caldarone, BJ; Terzi, D; Traynor, JR; Zachariou, V | 1 |
| Barry, D; Petry, NM; Sullivan, B | 1 |
| Brooner, RK; Kidorf, M; King, VL; Kolodner, K; Neufeld, K; Peirce, J | 1 |
| Allison, DW; Bufalino, MR; Clarke, L; Hansen, DM; Razavi, R; Steffensen, SC; Ting-A Kee, R; van der Kooy, D; Vargas-Perez, H; Walton, CH | 1 |
| Bickel, WK; Buchhalter, AR; Chopra, MP; Gatchalian, KM; Jackson, LC; Landes, RD; Marsch, LA; Stitzer, ML | 1 |
| Jiang, F; Khroyan, TV; Olsen, C; Polgar, WE; Toll, L; Zaveri, NT | 1 |
| Omelchenko, N; Sesack, SR | 1 |
| Robledo, P | 1 |
| Fadda, P; Fattore, L; Fratta, W; Spano, MS | 1 |
| Guidali, C; Massi, P; Parolaro, D; Realini, N; Rubino, T; Viganò, D | 1 |
| Maldonado, R | 1 |
| Bechard, M; Bishop, SF; Gholizadeh, S; Lauzon, NM; Laviolette, SR | 1 |
| Butelman, ER; Kreek, MJ; Narita, M; Niikura, K; Suzuki, T | 1 |
| Johansson, B; Terenius, L | 1 |
| Chen, SL; Kao, JH; Law, PY; Loh, HH; Ma, HI; Tao, PL | 1 |
| Greenwald, MK; Lundahl, LH; Steinmiller, CL | 1 |
| Bickel, WK; Christensen, DR; Jackson, L; Jones, BA; Landes, RD; Mancino, M | 1 |
| Abou-Saleh, M; Checinski, K; Clark, L; Davis, P; King, M; Mehta, MA; Passetti, F; White, S | 1 |
| Bishop, S; Chi, N; Lauzon, N; Laviolette, SR; Sun, N; Tan, H | 1 |
| Berger, AC; Whistler, JL | 1 |
| Huang, BE; McMillan, DE; Robles, E; Simpson, PM | 1 |
| Chang, YJ; Du, J; Evans, E; Hser, YI; Huang, D; Jiang, H; Li, J; Peng, C; Roll, J; Stitzer, ML; Wu, F; Zhang, B; Zhang, C; Zhang, R; Zhao, M | 1 |
| Bishop, SF; Chi, N; Gholizadeh, S; Lauzon, NM; Laviolette, SR; Lintas, A; Sun, N; Tan, H | 1 |
| Bailey, J; Barh, D; Blum, K; Bowirrat, A; Braverman, ER; Chen, AL; Chen, TJ; Damle, U; Downs, BW; Femino, J; Fornari, F; Giordano, J; Kerner, M; Morse, S; Oscar-Berman, M; Rector, C; Simpatico, T | 1 |
| Busch, EL; Elman, I; Langleben, DD; O'Brien, CP | 1 |
| Badiani, A; Belin, D; Calu, D; Epstein, D; Shaham, Y | 1 |
| Mori, T; Narita, M; Shibasaki, M; Suzuki, T; Torigoe, K; Yoshizawa, K | 1 |
| Bishop, SF; Chi, N; Lauzon, NM; Laviolette, SR; Lintas, A; Sun, N; Tan, H | 1 |
| Cong, B; Li, S; Ma, C; Ni, Z; Wen, D; Yang, S; Yu, H | 1 |
| Mattioli, L; Perfumi, M; Titomanlio, F | 1 |
| Barrot, M; Bourdy, R | 1 |
| De Vries, TJ; Peters, J | 1 |
| Butelman, ER; Kreek, MJ; Levran, O; Reed, B; Schlussman, SD; Zhou, Y | 1 |
| Bryant, CD; Cheng, R; Guido, MA; Kole, LA | 1 |
| Badger, GJ; Bickel, WK; Giordano, LA; Jacobs, EA; Loewenstein, G; Marsch, L | 1 |
| Farabee, D; Huber, A; Ling, W; McCann, M; Rawson, RA; Reiber, C; Shoptaw, S | 1 |
| Aston-Jones, G; Harris, GC | 1 |
| Gallegos, RA; Henriksen, SJ; Laviolette, SR; van der Kooy, D | 1 |
| Kornetsky, C | 1 |
| Liu, J; Schulteis, G | 1 |
| Laviolette, SR; van der Kooy, D | 1 |
| Hawes, JJ; Picciotto, MR | 1 |
| Cossu, G; Deiana, S; Fadda, P; Fattore, L; Fratta, W; Scherma, M; Spano, SM | 1 |
| Burns, LH; Olmstead, MC | 1 |
| Bajpai, LK; Bruijnzeel, AW; Dennis, DM; Gold, M; Lewis, B; Morey, TE | 1 |
| Berton, O; Bolanos, CA; Cassidy, MP; Dileone, RJ; Kelz, MB; Kumar, A; Nestler, EJ; Selley, DE; Shaw-Lutchman, T; Sim-Selley, LJ; Theobald, D; Zachariou, V | 1 |
| Bickel, WK; Buchhalter, AR; Gatchalian, KM; Yi, R | 1 |
| Cao, J; Dong, Z; Xu, L | 1 |
| Alguacil, LF; Herradon, G; Morales, L; Perez-Garcia, C | 1 |
| Ersche, KD; Robbins, TW; Roiser, JP; Sahakian, BJ | 1 |
| Szara, S | 1 |
| Bain, G; Kornetsky, C | 1 |
| Fowler, JS; Hitzemann, R; Volkow, ND; Wang, GJ | 1 |
| Balducci, C; Koob, GF; Pulvirenti, L | 1 |
| Badger, GJ; Bickel, WK; Madden, GJ; Petry, NM | 1 |
| Cohen, E; Gagin, R; Kook, N; Shavit, Y | 1 |
| Bechara, A; Nader, K; van der Kooy, D | 1 |
| Kosofsky, BE; Malanga, CJ | 1 |
| Elmer, GI; Shippenberg, TS | 1 |
| Bickel, WK; Jacobs, EA; Madden, GJ | 1 |
| Griffith, JD; Roark, RR; Rowan-Szal, GA; Simpson, DD | 1 |
| Bilecki, W; Przewłocki, R | 1 |
| Dockstader, CL; Grandy, DK; Low, MJ; Rubinstein, M; van der Kooy, D | 1 |
| Ball, SA; Carroll, KM; Eagan, DA; Frankforter, TL; Nich, C; O'Connor, PG; Rounsaville, BJ; Shi, J; Triffleman, EG | 1 |
| Garzón, M; Pickel, VM | 1 |
| Chevalley, AF; Künig, G; Leenders, KL; Magyar, S; Martin-Soelch, C; Mino, A; Missimer, J; Schultz, W | 1 |
| Wallace, CJ | 1 |
| Bain, GT; Huston-Lyons, D; Kornetsky, C | 1 |
| Bozarth, MA; Wise, RA | 1 |
46 review(s) available for s,n,n'-tripropylthiocarbamate and Addiction, Opioid
| Article | Year |
|---|---|
Neurocircuitry basis of the opioid use disorder-post-traumatic stress disorder comorbid state: conceptual analyses using a dimensional framework.
Topics: Brain; Cognitive Dysfunction; Comorbidity; Executive Function; Humans; Nerve Net; Opioid-Related Disorders; Reward; Stress Disorders, Post-Traumatic | 2022 |
Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement.
Topics: Animals; Brain; Motivation; Neurobiology; Opioid-Related Disorders; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders | 2020 |
Anhedonia in chronic pain and prescription opioid misuse.
Topics: Adult; Aged; Analgesics, Opioid; Anhedonia; Case-Control Studies; Chronic Pain; Female; Humans; Male; Middle Aged; Opioid-Related Disorders; Pleasure; Reward; Self Report; Young Adult | 2020 |
Glial neuroimmune signaling in opioid reward.
Topics: Animals; Astrocytes; Brain; Humans; Microglia; Neuroglia; Neuroimmunomodulation; Opioid-Related Disorders; Reward; Signal Transduction | 2020 |
Bouncing back: Brain rehabilitation amid opioid and stimulant epidemics.
Topics: Amphetamine-Related Disorders; Brain; Cocaine-Related Disorders; Cognition; Craving; Diffusion Tensor Imaging; Electroencephalography; Evoked Potentials; Frontal Lobe; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Methamphetamine; Neostriatum; Opioid-Related Disorders; Recovery of Function; Recurrence; Reward; Treatment Outcome | 2019 |
The role of the gut microbiome in opioid use.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Brain; Drug Tolerance; Gastrointestinal Microbiome; Humans; Motivation; Opioid-Related Disorders; Reward | 2020 |
Glutamatergic Systems and Memory Mechanisms Underlying Opioid Addiction.
Topics: Animals; Brain; Dopamine; Glutamic Acid; Humans; Memory; Morphine; Opioid-Related Disorders; Reward; Signal Transduction; Synaptic Transmission | 2021 |
Non-Opioid Treatments for Opioid Use Disorder: Rationales and Data to Date.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Brain; Buprenorphine; Disease Models, Animal; Endocannabinoids; Glutamic Acid; Humans; Methadone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Orexins; Reward; Secondary Prevention; Signal Transduction; Treatment Outcome | 2020 |
Review of addiction risk potential associated with adolescent opioid use.
Topics: Adolescent; Adult; Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Brain; Drug Tolerance; Female; Humans; Locomotion; Male; Mice; Opioid-Related Disorders; Rats; Reinforcement, Psychology; Reward; Risk Factors; Substance Withdrawal Syndrome; Substance-Related Disorders | 2020 |
Neurological correlates of brain reward circuitry linked to opioid use disorder (OUD): Do homo sapiens acquire or have a reward deficiency syndrome?
Topics: Behavior, Addictive; Brain; Humans; Opioid-Related Disorders; Reward; Syndrome | 2020 |
Progress in opioid reward research: From a canonical two-neuron hypothesis to two neural circuits.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Dopamine; Dopaminergic Neurons; gamma-Aminobutyric Acid; Humans; Mesencephalon; Neural Pathways; Opioid-Related Disorders; Pars Compacta; Pars Reticulata; Receptors, Opioid, mu; Reward; Synapses; Ventral Tegmental Area | 2021 |
Oxycodone in the Opioid Epidemic: High 'Liking', 'Wanting', and Abuse Liability.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Humans; Opioid Epidemic; Opioid-Related Disorders; Oxycodone; Pain; Reward | 2021 |
Cellular and behavioral basis of cannabinioid and opioid interactions: Implications for opioid dependence and withdrawal.
Topics: Analgesics, Opioid; Cannabinoids; Humans; Opioid Peptides; Opioid-Related Disorders; Reward | 2022 |
Circuit and neuropeptide mechanisms of the paraventricular thalamus across stages of alcohol and drug use.
Topics: Alcoholism; Animals; Humans; Nerve Net; Neuropeptides; Opioid-Related Disorders; Paraventricular Hypothalamic Nucleus; Reward; Substance-Related Disorders | 2021 |
Oxytocin and opioid addiction revisited: old drug, new applications.
Topics: Animals; Humans; Mood Disorders; Opioid-Related Disorders; Oxytocin; Reward | 2018 |
The risk for problematic opioid use in chronic pain: What can we learn from studies of pain and reward?
Topics: Analgesics; Analgesics, Opioid; Animals; Chronic Pain; Humans; Opioid-Related Disorders; Reward | 2018 |
Role of orexin type-1 receptors in paragiganto-coerulear modulation of opioid withdrawal and tolerance: A site specific focus.
Topics: Animals; Drug Tolerance; Humans; Locus Coeruleus; Medulla Oblongata; Opioid-Related Disorders; Orexin Receptors; Reward; Signal Transduction; Substance Withdrawal Syndrome | 2017 |
Serotonin-1A receptor dependent modulation of pain and reward for improving therapy of chronic pain.
Topics: Analgesics; Analgesics, Opioid; Animals; Brain; Chronic Pain; Dopamine; Humans; Opioid-Related Disorders; Pain Perception; Pain Threshold; Receptor, Serotonin, 5-HT1A; Reward; Serotonin 5-HT1 Receptor Agonists; Signal Transduction | 2018 |
Relapse to opioid seeking in rat models: behavior, pharmacology and circuits.
Topics: Animals; Brain; Craving; Disease Models, Animal; Extinction, Psychological; Opioid-Related Disorders; Rats; Recurrence; Reward; Substance Withdrawal Syndrome | 2019 |
Frontal cortex dysfunction as a target for remediation in opiate use disorder: Role in cognitive dysfunction and disordered reward systems.
Topics: Analgesics, Opioid; Cognition; Cognitive Dysfunction; Frontal Lobe; Humans; Opioid-Related Disorders; Reward | 2018 |
The potential role of the orexin reward system in future treatments for opioid drug abuse.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Disease Models, Animal; Drug-Seeking Behavior; Humans; Hypothalamic Area, Lateral; Morphine; Neural Pathways; Opioid-Related Disorders; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Reward | 2020 |
Intact responses to non-drug rewards in long-term opioid maintenance treatment.
Topics: Adult; Bayes Theorem; Case-Control Studies; Choice Behavior; Decision Making; Female; Humans; Models, Psychological; Opiate Substitution Treatment; Opioid-Related Disorders; Reward | 2019 |
The failing cascade: Comorbid post traumatic stress- and opioid use disorders.
Topics: Brain; Comorbidity; Humans; Opioid-Related Disorders; Reward; Stress Disorders, Post-Traumatic | 2019 |
[Tobacco use and illicit substance use disorders: what should we have to do?].
Topics: Behavior, Addictive; Cocaine-Related Disorders; Combined Modality Therapy; Comorbidity; Disease Susceptibility; Dopamine; Global Health; Humans; Illicit Drugs; Marijuana Abuse; Nicotine; Opioid-Related Disorders; Receptors, Dopamine D2; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Smoking; Smoking Cessation; Substance-Related Disorders; Tobacco Use Disorder | 2013 |
Delta opioid receptors in brain function and diseases.
Topics: Animals; Brain; Brain Ischemia; Emotions; Epilepsy; Humans; Hypoxia; Motor Activity; Opioid-Related Disorders; Receptors, Opioid, delta; Reward | 2013 |
New approach to the neurobiological mechanisms of addiction.
Topics: Alcoholism; Behavior, Addictive; Benzodiazepines; Brain; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Chromatin; Epigenesis, Genetic; Humans; Learning; Marijuana Abuse; Memory; Nerve Tissue Proteins; Neurotransmitter Agents; Opioid-Related Disorders; Psychotropic Drugs; Reward; Signal Transduction; Substance-Related Disorders | 2013 |
Animal models for opioid addiction drug discovery.
Topics: Animals; Disease Models, Animal; Drug Discovery; Drug Tolerance; Humans; Opioid-Related Disorders; Recurrence; Reward; Substance Withdrawal Syndrome | 2014 |
Neurogenetics of acute and chronic opiate/opioid abstinence: treating symptoms and the cause.
Topics: Animals; Cannabinoids; Dopamine; Drug-Seeking Behavior; Evidence-Based Medicine; gamma-Aminobutyric Acid; Glutamates; Humans; Models, Neurological; Neurotransmitter Agents; Opioid Peptides; Opioid-Related Disorders; Reward; Serotonin; Substance Withdrawal Syndrome; United States | 2017 |
Sex differences in analgesic, reinforcing, discriminative, and motoric effects of opioids.
Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Discrimination, Psychological; Female; Humans; Male; Motor Activity; Opioid-Related Disorders; Reinforcement, Psychology; Reward; Sex Characteristics | 2008 |
Cannabinoids, opioids and MDMA: neuropsychological interactions related to addiction.
Topics: Amphetamine-Related Disorders; Animals; Behavior, Addictive; Brain; Cannabinoid Receptor Modulators; Central Nervous System Stimulants; Humans; Marijuana Abuse; Mice; Mice, Knockout; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Opioid Peptides; Opioid-Related Disorders; Rats; Receptors, Opioid; Reinforcement, Psychology; Reward | 2010 |
Cannabinoid-opioid interactions in drug discrimination and self-administration: effect of maternal, postnatal, adolescent and adult exposure to the drugs.
Topics: Adolescent; Adult; Age Factors; Animals; Behavior, Addictive; Brain; Cannabinoid Receptor Modulators; Discrimination, Psychological; Female; Gestational Age; Humans; Male; Marijuana Abuse; Opioid Peptides; Opioid-Related Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Cannabinoid, CB1; Receptors, Opioid, mu; Recurrence; Reinforcement, Psychology; Reward; Risk Factors; Self Medication; Young Adult | 2010 |
Cellular mechanisms underlying the interaction between cannabinoid and opioid system.
Topics: Analgesics, Opioid; Animals; Brain; Cannabinoid Receptor Modulators; Cannabinoids; Cognition; Drug Interactions; Emotions; Humans; Immune System; Opioid Peptides; Opioid-Related Disorders; Pain; Receptor Cross-Talk; Receptors, Cannabinoid; Receptors, Opioid; Reward; Signal Transduction; Substance Withdrawal Syndrome | 2010 |
[The endogenous opioid system and drug addiction].
Topics: Alcoholism; Amphetamine-Related Disorders; Animals; Cocaine-Related Disorders; Endorphins; Humans; Marijuana Abuse; Opioid-Related Disorders; Reward; Substance-Related Disorders; Tobacco Use Disorder | 2010 |
The opioid systems--panacea and nemesis.
Topics: Allostasis; Analgesics, Opioid; Animals; Behavior, Addictive; Conditioning, Classical; Enkephalins; Humans; Mice; Opioid Peptides; Opioid-Related Disorders; Pro-Opiomelanocortin; Protein Precursors; Rats; Receptors, Opioid, mu; Reward | 2010 |
Opiate versus psychostimulant addiction: the differences do matter.
Topics: Amphetamine-Related Disorders; Animals; Behavior, Addictive; Brain; Cocaine-Related Disorders; Humans; Opioid-Related Disorders; Reward | 2011 |
A new control center for dopaminergic systems: pulling the VTA by the tail.
Topics: Adaptation, Psychological; Afferent Pathways; Animals; Arousal; Avoidance Learning; Brain Mapping; Dopamine; Dopaminergic Neurons; Efferent Pathways; Emotions; GABAergic Neurons; Mesencephalon; Models, Neurological; Motor Activity; Opioid-Related Disorders; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Receptors, Opioid, mu; Reward; Ventral Tegmental Area | 2012 |
Glutamate mechanisms underlying opiate memories.
Topics: Amygdala; Conditioning, Psychological; Extinction, Psychological; Glutamic Acid; Hippocampus; Humans; Memory; Nucleus Accumbens; Opioid-Related Disorders; Prefrontal Cortex; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Reward | 2012 |
Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics.
Topics: Animals; Basal Ganglia; Cocaine-Related Disorders; Dopamine; Dopaminergic Neurons; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Hypothalamo-Hypophyseal System; Limbic System; Methadone; Mice; Mice, Knockout; Neuropeptides; Opioid-Related Disorders; Pharmacogenetics; Pituitary-Adrenal System; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, mu; Reward; Stress, Physiological; Stress, Psychological | 2012 |
Brain-stimulation reward, morphine-induced oral stereotypy, and sensitization: implications for abuse.
Topics: Animals; Brain; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Morphine; Narcotics; Opioid-Related Disorders; Reward; Self Stimulation; Stereotypic Movement Disorder | 2004 |
Endocannabinoid system and opioid addiction: behavioural aspects.
Topics: Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Drug Tolerance; Endocannabinoids; Humans; Opioid-Related Disorders; Reward; Self Administration; Self Stimulation | 2005 |
A two-separate-motivational-systems hypothesis of opioid addiction.
Topics: Animals; Conditioning, Operant; Dopamine; Humans; Motivation; Opioid-Related Disorders; Reward; Self Administration; Substance Withdrawal Syndrome; Terminology as Topic | 1998 |
Mechanisms of action of drugs of abuse on the developing fetal brain.
Topics: Alcoholism; Animals; Brain; Child; Child Development; Child Rearing; Cocaine; Cocaine-Related Disorders; Confounding Factors, Epidemiologic; Disease Models, Animal; Ethanol; Female; Fetus; Humans; Illicit Drugs; Narcotics; Nutritional Physiological Phenomena; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reinforcement, Psychology; Reward; Substance-Related Disorders | 1999 |
The neurobiology of opiate reinforcement.
Topics: Animals; Dopamine; Humans; Narcotics; Neurobiology; Opioid-Related Disorders; Receptors, Opioid; Reinforcement, Psychology; Reward; Serotonin | 1998 |
Contingency management in outpatient methadone treatment: a meta-analysis.
Topics: Behavior Therapy; Humans; Methadone; Narcotics; Opioid-Related Disorders; Reward; Treatment Outcome | 2000 |
Effect of opioids on Ca2+/cAMP responsive element binding protein.
Topics: Animals; Brain; Cyclic AMP Response Element-Binding Protein; Humans; Narcotics; Opioid-Related Disorders; Phosphorylation; Reward | 2000 |
Brain mechanisms of drug reward and euphoria.
Topics: Animals; Brain; Central Nervous System Stimulants; Euphoria; Humans; Narcotics; Nucleus Accumbens; Opioid-Related Disorders; Receptors, Dopamine; Reward; Stimulation, Chemical; Substance-Related Disorders | 1985 |
20 trial(s) available for s,n,n'-tripropylthiocarbamate and Addiction, Opioid
| Article | Year |
|---|---|
Mindfulness-Oriented Recovery Enhancement remediates anhedonia in chronic opioid use by enhancing neurophysiological responses during savoring of natural rewards.
Topics: Analgesics, Opioid; Anhedonia; Chronic Pain; Humans; Mindfulness; Opioid-Related Disorders; Reward | 2023 |
Minocycline attenuates oxycodone-induced positive subjective responses in non-dependent, recreational opioid users.
Topics: Adult; Analgesia; Analgesics, Opioid; Anti-Bacterial Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Microglia; Middle Aged; Minocycline; New York; Opioid-Related Disorders; Oxycodone; Reward; Young Adult | 2021 |
Relapse prevention: Using sound to reduce the probability of recidivism and suffering following detoxification.
Topics: Adult; Analgesics, Opioid; Behavior, Addictive; Brain; Female; Florida; Humans; Male; Methadone; Middle Aged; Music Therapy; Narcotics; Neuronal Plasticity; Opioid-Related Disorders; Pilot Projects; Probability; Quality of Life; Recidivism; Recurrence; Reward; Secondary Prevention; Substance-Related Disorders; Young Adult | 2018 |
Effectiveness of prize-based contingency management in a methadone maintenance program in China.
Topics: Adult; Behavior Therapy; China; Female; Humans; Male; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Compliance; Reward | 2013 |
Comparison of a drug versus money and drug versus drug self-administration choice procedure with oxycodone and morphine in opioid addicts.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Buprenorphine; Choice Behavior; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; In Vitro Techniques; Male; Middle Aged; Morphine; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Pain Measurement; Pupil; Reward; Self Administration; Surveys and Questionnaires; Time Factors; Token Economy; Young Adult | 2013 |
Attentional bias for nondrug reward is magnified in addiction.
Topics: Adult; Attention; Behavior, Addictive; Female; Humans; Impulsive Behavior; Male; Memory, Short-Term; Methadone; Opioid-Related Disorders; Photic Stimulation; Reaction Time; Reward | 2013 |
Abnormal brain activity during a reward and loss task in opiate-dependent patients receiving methadone maintenance therapy.
Topics: Adult; Analysis of Variance; Brain; Brain Mapping; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methadone; Opioid-Related Disorders; Oxygen; Probability; Reward; Time Factors; Young Adult | 2014 |
Abuse potential of intravenous oxycodone/naloxone solution in nondependent recreational drug users.
Topics: Adolescent; Adult; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Humans; Injections, Intravenous; Male; Middle Aged; Naloxone; Opioid-Related Disorders; Oxycodone; Reward; Young Adult | 2014 |
Neurophysiological evidence for remediation of reward processing deficits in chronic pain and opioid misuse following treatment with Mindfulness-Oriented Recovery Enhancement: exploratory ERP findings from a pilot RCT.
Topics: Analgesics, Opioid; Chronic Pain; Evoked Potentials, Visual; Female; Humans; Individuality; Male; Middle Aged; Mindfulness; Opioid-Related Disorders; Pilot Projects; Reward | 2015 |
Restructuring Hedonic Dysregulation in Chronic Pain and Prescription Opioid Misuse: Effects of Mindfulness-Oriented Recovery Enhancement on Responsiveness to Drug Cues and Natural Rewards.
Topics: Adult; Analgesics, Opioid; Chronic Pain; Cues; Female; Humans; Male; Middle Aged; Mindfulness; Opioid-Related Disorders; Prescription Drug Misuse; Reward; Treatment Outcome | 2017 |
Comparable efficacy of contingency management for cocaine dependence among African American, Hispanic, and White methadone maintenance clients.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Behavior Therapy; Black or African American; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Female; Hispanic or Latino; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Psychiatric Status Rating Scales; Reward; Substance Abuse Detection; Treatment Outcome; White People | 2009 |
Improving substance abuse treatment enrollment in community syringe exchangers.
Topics: Adult; Baltimore; Drug Users; Female; Harm Reduction; Humans; Male; Motivation; Needle-Exchange Programs; Opioid-Related Disorders; Reward; Substance Abuse Treatment Centers; Substance Abuse, Intravenous | 2009 |
Buprenorphine medication versus voucher contingencies in promoting abstinence from opioids and cocaine.
Topics: Adolescent; Adult; Buprenorphine; Cocaine-Related Disorders; Directive Counseling; Female; Humans; Male; Middle Aged; Opioid-Related Disorders; Patient Compliance; Reward; Secondary Prevention | 2009 |
Sustained release d-amphetamine reduces cocaine but not 'speedball'-seeking in buprenorphine-maintained volunteers: a test of dual-agonist pharmacotherapy for cocaine/heroin polydrug abusers.
Topics: Adolescent; Adult; Buprenorphine; Choice Behavior; Cocaine; Cocaine-Related Disorders; Delayed-Action Preparations; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Seeking Behavior; Female; Humans; Hydromorphone; Male; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Reinforcement Schedule; Reward; Substance Withdrawal Syndrome | 2010 |
Effects of a randomized contingency management intervention on opiate abstinence and retention in methadone maintenance treatment in China.
Topics: Adult; Analysis of Variance; China; Female; HIV Infections; Humans; Male; Methadone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Compliance; Patient Dropouts; Recurrence; Reward; Substance Abuse, Intravenous; Time Factors; Treatment Outcome | 2011 |
Depot naltrexone decreases rewarding properties of sugar in patients with opioid dependence.
Topics: Adult; Analysis of Variance; Cues; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Motivation; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Pilot Projects; Reward; Substance Abuse, Intravenous; Sucrose; Taste Perception | 2012 |
A comparison of contingency management and cognitive-behavioral approaches during methadone maintenance treatment for cocaine dependence.
Topics: Adult; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Female; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Patient Compliance; Reward; Substance Abuse Detection; Treatment Outcome | 2002 |
Impulsive and self-control choices in opioid-dependent patients and non-drug-using control participants: drug and monetary rewards.
Topics: Adolescent; Adult; Female; Heroin; Humans; Impulsive Behavior; Male; Narcotics; Opioid-Related Disorders; Personality Tests; Reward | 1997 |
Discounting of delayed rewards in opioid-dependent outpatients: exponential or hyperbolic discounting functions?
Topics: Adult; Buprenorphine; Female; Heroin; Humans; Male; Motivation; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Reward; Time Factors | 1999 |
Targeting behavioral therapies to enhance naltrexone treatment of opioid dependence: efficacy of contingency management and significant other involvement.
Topics: Adult; Behavior Therapy; Combined Modality Therapy; Family Therapy; Female; Humans; Interpersonal Relations; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Dropouts; Reward; Substance Abuse Detection; Treatment Outcome; Treatment Refusal | 2001 |
106 other study(ies) available for s,n,n'-tripropylthiocarbamate and Addiction, Opioid
| Article | Year |
|---|---|
Rewarding recovery: the time is now for contingency management for opioid use disorder.
Topics: Humans; Motivation; Opioid-Related Disorders; Reward | 2022 |
Opioid Use Disorder and Alternative mRNA Splicing in Reward Circuitry.
Topics: Analgesics, Opioid; DNA, Recombinant; Genome-Wide Association Study; Humans; Opioid-Related Disorders; Reward; RNA, Messenger; United States | 2022 |
Prefrontal cortical response to natural rewards and self-reported anhedonia are associated with greater craving among recently withdrawn patients in residential treatment for opioid use disorder.
Topics: Anhedonia; Craving; Humans; Opioid-Related Disorders; Prefrontal Cortex; Recurrence; Residential Treatment; Reward; Self Report | 2022 |
Endomorphin analog ZH853 shows low reward, tolerance, and affective-motivational signs of withdrawal, while inhibiting opioid withdrawal and seeking.
Topics: Analgesics, Opioid; Animals; Female; Humans; Male; Mice; Morphine; Narcotics; Opioid-Related Disorders; Oxycodone; Rats; Reward; Substance Withdrawal Syndrome | 2023 |
Transcriptional signatures of heroin intake and relapse throughout the brain reward circuitry in male mice.
Topics: Animals; Brain; Genome-Wide Association Study; Heroin; Humans; Male; Mice; Opioid-Related Disorders; Recurrence; Reward | 2023 |
The hidden-zero effect in male individuals with opioid use disorder.
Topics: Delay Discounting; Humans; Male; Opioid-Related Disorders; Reward | 2023 |
Effects of the novel selective κ-opioid receptor agonist NP-5497-KA on morphine-induced reward-related behaviors.
Topics: Analgesics, Opioid; Animals; Humans; Mice; Mice, Inbred C57BL; Morphine; Opioid-Related Disorders; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward | 2023 |
Mindfulness-Oriented Recovery Enhancement remediates hedonic dysregulation in opioid users: Neural and affective evidence of target engagement.
Topics: Analgesics, Opioid; Chronic Pain; Cues; Female; Humans; Male; Middle Aged; Mindfulness; Opioid-Related Disorders; Reward | 2019 |
A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction.
Topics: 3' Untranslated Regions; Basic Helix-Loop-Helix Transcription Factors; Circadian Rhythm; Genetic Predisposition to Disease; Humans; Opioid-Related Disorders; Period Circadian Proteins; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Receptors, Vasoactive Intestinal Peptide, Type II; Repressor Proteins; Reward; RNA, Long Noncoding | 2019 |
On the early life origins of vulnerability to opioid addiction.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Female; Opioid-Related Disorders; Origin of Life; Rats; Reward | 2021 |
The psychiatrist at the centre of the opioid crisis.
Topics: Alcoholism; Cocaine-Related Disorders; Dopamine; Drug Overdose; Heroin Dependence; History, 20th Century; History, 21st Century; Humans; Marijuana Abuse; Methadone; Methamphetamine; Naloxone; National Institutes of Health (U.S.); Neurosciences; Opioid-Related Disorders; Positron-Emission Tomography; Prefrontal Cortex; Psychiatry; Reward; Socioeconomic Factors; United States | 2020 |
Classics in Chemical Neuroscience: Buprenorphine.
Topics: Analgesics, Opioid; Buprenorphine; Humans; Narcotic Antagonists; Opioid-Related Disorders; Reward | 2020 |
Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the basolateral amygdala.
Topics: Animals; Basolateral Nuclear Complex; Conditioning, Psychological; Corticosterone; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Humans; Male; Mifepristone; Morphine; Nerve Net; Nucleus Accumbens; Opioid-Related Disorders; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Receptors, Glucocorticoid; Reward; Signal Transduction; Stereotaxic Techniques; Stress, Psychological | 2020 |
Decreased Neuronal Excitability in Medial Prefrontal Cortex during Morphine Withdrawal is associated with enhanced SK channel activity and upregulation of small GTPase Rac1.
Topics: Action Potentials; Animals; Conditioning, Psychological; Disease Models, Animal; Humans; Male; Morphine; Neurons; Opioid-Related Disorders; Prefrontal Cortex; rac1 GTP-Binding Protein; Rats; Reward; Small-Conductance Calcium-Activated Potassium Channels; Substance Withdrawal Syndrome; Up-Regulation | 2020 |
Building and testing coherent models of treatment.
Topics: Humans; Opioid-Related Disorders; Pain; Psychosocial Intervention; Reward | 2020 |
The kappa-opioid receptor agonist, nalfurafine, blocks acquisition of oxycodone self-administration and oxycodone's conditioned rewarding effects in male rats.
Topics: Analgesics, Opioid; Animals; Conditioning, Classical; Dose-Response Relationship, Drug; Male; Morphinans; Opioid-Related Disorders; Oxycodone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, kappa; Reinforcement, Psychology; Reward; Self Administration; Spiro Compounds; Substance-Related Disorders | 2020 |
Conditioned Place Preference (CPP) in Rats: From Conditioning to Reinstatement Test.
Topics: Analgesics, Opioid; Animals; Behavior Control; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Male; Morphine; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reward | 2021 |
Analysis of Opioid-Seeking Behavior Through the Intravenous Self-Administration Reinstatement Model in Rats.
Topics: Administration, Intravenous; Analgesics, Opioid; Animals; Behavior Control; Behavior, Addictive; Conditioning, Operant; Cues; Disease Models, Animal; Drug-Seeking Behavior; Heroin; Infusions, Intravenous; Male; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration; Substance-Related Disorders | 2021 |
Sex-dependent effects of an Hnrnph1 mutation on fentanyl addiction-relevant behaviors but not antinociception in mice.
Topics: Analgesics, Opioid; Animals; Fentanyl; Heterogeneous-Nuclear Ribonucleoproteins; Male; Mice; Mice, Inbred C57BL; Motor Activity; Mutation; Nociception; Opioid-Related Disorders; Reward; Sex Factors | 2021 |
Psychosocial intervention and the reward system in pain and opioid misuse: new opportunities and directions.
Topics: Analgesics, Opioid; Chronic Pain; Humans; Opioid-Related Disorders; Pain; Prescription Drug Misuse; Psychosocial Intervention; Reward | 2020 |
Adolescent oxycodone exposure inhibits withdrawal-induced expression of genes associated with the dopamine transmission.
Topics: Analgesics, Opioid; Animals; Dopamine; Epigenesis, Genetic; Gene Expression; Male; Mice; Morphine; Opioid-Related Disorders; Oxycodone; Reward; Self Administration; Ventral Tegmental Area | 2021 |
Novel circuit biomarker of impulsivity and craving in male heroin-dependent individuals.
Topics: Adult; Behavior, Addictive; Biomarkers; Brain; Brain Mapping; Case-Control Studies; Cerebral Cortex; Corpus Striatum; Craving; Diffusion Tensor Imaging; Gyrus Cinguli; Heroin; Heroin Dependence; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Male; Middle Aged; Opioid-Related Disorders; Reward | 2021 |
Functional evaluation of NK
Topics: Adult; Amygdala; Analgesics, Opioid; Brain; Brain Mapping; Conditioning, Psychological; Craving; Cues; Female; Heroin; Heroin Dependence; Humans; Magnetic Resonance Imaging; Male; Neurokinin-1 Receptor Antagonists; Opiate Alkaloids; Opioid-Related Disorders; Receptors, Neurokinin-1; Reward; Young Adult | 2021 |
Reward Responsiveness in Patients with Opioid Use Disorder on Opioid Agonist Treatment: Role of Comorbid Chronic Pain.
Topics: Analgesics, Opioid; Chronic Pain; Humans; Opioid-Related Disorders; Reward | 2021 |
High fructose corn syrup alters behavioural and neurobiological responses to oxycodone in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Psychological; Diet; Dopamine; High Fructose Corn Syrup; Locomotion; Male; Nucleus Accumbens; Opioid-Related Disorders; Oxycodone; Rats; Rats, Sprague-Dawley; Reward | 2021 |
It is never as good the second time around: Brain areas involved in salience processing habituate during repeated drug cue exposure in treatment engaged abstinent methamphetamine and opioid users.
Topics: Adult; Amphetamine-Related Disorders; Analgesics, Opioid; Brain; Brain Mapping; Cues; Female; Habituation, Psychophysiologic; Humans; Magnetic Resonance Imaging; Male; Methamphetamine; Opioid-Related Disorders; Reward | 2021 |
Casein kinase 1-epsilon deletion increases mu opioid receptor-dependent behaviors and binge eating1.
Topics: Animals; Bulimia; Casein Kinase 1 epsilon; Conditioning, Classical; Corpus Striatum; Female; Gene Deletion; Male; Mice; Mice, Inbred C57BL; Opioid-Related Disorders; Receptors, Opioid, mu; Reward; Transcriptome | 2017 |
Opiate exposure state controls dopamine D3 receptor and cdk5/calcineurin signaling in the basolateral amygdala during reward and withdrawal aversion memory formation.
Topics: Analgesics, Opioid; Animals; Association Learning; Avoidance Learning; Basolateral Nuclear Complex; Calcineurin; Conditioning, Psychological; Cyclin-Dependent Kinase 5; Disease Models, Animal; Heroin; Male; Memory; Opioid-Related Disorders; Ranolazine; Rats, Sprague-Dawley; Receptors, Dopamine D3; Reward; Signal Transduction; Spatial Behavior; Substance Withdrawal Syndrome | 2017 |
Regional cerebral blood flow in opiate dependence relates to substance use and neuropsychological performance.
Topics: Adult; Alcoholism; Analgesics, Opioid; Brain; Buprenorphine; Case-Control Studies; Cerebrovascular Circulation; Cigarette Smoking; Cognition; Executive Function; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Opiate Substitution Treatment; Opioid-Related Disorders; Reward; Self-Control | 2018 |
Reward and punishment-based compound cue learning and generalization in opiate dependency.
Topics: Adult; Cognitive Dysfunction; Cues; Female; Generalization, Psychological; Humans; Male; Middle Aged; Opioid-Related Disorders; Psychomotor Performance; Punishment; Reward; Transfer, Psychology; Visual Perception | 2017 |
Sustained opioid antagonism modulates striatal sensitivity to baby schema in opioid use disorder.
Topics: Adult; Brain; Delayed-Action Preparations; Facial Recognition; Female; Humans; Magnetic Resonance Imaging; Maternal Behavior; Motivation; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Reward | 2018 |
Chemists seek antiaddiction drugs to battle hijacked brain.
Topics: 4-Aminobutyrate Transaminase; Animals; Behavior, Addictive; Brain; Craving; Drug Design; Enzyme Inhibitors; gamma-Aminobutyric Acid; Humans; Opioid-Related Disorders; Reward | 2018 |
Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal.
Topics: Animals; Behavior, Animal; Brain; Conditioning, Psychological; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Male; Morphine; Opioid-Related Disorders; Rats, Sprague-Dawley; Reward; Serotonin; Substance Withdrawal Syndrome; Synaptic Transmission; Time Factors; Ultrasonic Waves; Vocalization, Animal | 2018 |
[Neurobiology of opioid dependence].
Topics: Analgesics, Opioid; Dopamine; Humans; Opioid-Related Disorders; Reward | 2018 |
Chronic Oxycodone Self-administration Altered Reward-related Genes in the Ventral and Dorsal Striatum of C57BL/6J Mice: An RNA-seq Analysis.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Gene Expression; Male; Mice, Inbred C57BL; Opioid-Related Disorders; Oxycodone; Reward; Self Administration; Sequence Analysis, RNA; Ventral Striatum | 2018 |
Removal of microglial-specific MyD88 signaling alters dentate gyrus doublecortin and enhances opioid addiction-like behaviors.
Topics: Animals; Behavior, Addictive; Conditioning, Classical; Conditioning, Operant; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Hippocampus; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Microtubule-Associated Proteins; Morphine; Myeloid Differentiation Factor 88; Narcotics; Neural Stem Cells; Neurogenesis; Neurons; Neuropeptides; Opioid-Related Disorders; Reward | 2019 |
Methadone maintenance treatment patients with a history of childhood trauma succeed more in a cognitive paradigm that is associated with a negative reward.
Topics: Adult Survivors of Child Adverse Events; Cues; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Reversal Learning; Reward | 2019 |
Connectome-Based Prediction of Cocaine Abstinence.
Topics: Adult; Behavior Therapy; Brain; Cholinesterase Inhibitors; Cocaine-Related Disorders; Cognition; Connectome; Executive Function; Female; Functional Neuroimaging; Galantamine; Humans; Individuality; Machine Learning; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Opiate Substitution Treatment; Opioid-Related Disorders; Prognosis; Reward; Treatment Outcome | 2019 |
Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opioid Dependence.
Topics: Animals; Female; GABAergic Neurons; Male; Mice; Mice, Inbred C57BL; Opioid-Related Disorders; Raphe Nuclei; Receptors, Opioid, mu; Reward; Synaptic Transmission; Ventral Tegmental Area | 2019 |
Probability discounting of monetary gains and losses in opioid-dependent adults.
Topics: Adult; Analgesics, Opioid; Area Under Curve; Choice Behavior; Decision Making; Delay Discounting; Female; Humans; Impulsive Behavior; Male; Opioid-Related Disorders; Probability; Reward; Risk-Taking | 2019 |
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice.
Topics: Analgesics, Opioid; Animals; Brain; Conditioning, Psychological; Disease Models, Animal; Heroin; Locomotion; Male; Mice; Mice, Inbred C57BL; Morphine Derivatives; Opioid-Related Disorders; Reward | 2020 |
Oxycodone's Unparalleled Addictive Potential: Is it Time for a Moratorium?
Topics: Adult; Alaska; Analgesics, Opioid; Cross-Sectional Studies; Dopamine Agents; Female; Heroin Dependence; Humans; Male; Middle Aged; Opioid-Related Disorders; Oxycodone; Pain Management; Prescription Drug Misuse; Reward | 2019 |
[Neurobiology of opioid dependence].
Topics: Analgesics, Opioid; Humans; Opioid-Related Disorders; Reward | 2019 |
Neural reward response to substance-free activity images in opiate use disorder patients with depressive symptoms.
Topics: Adult; Behavior Therapy; Brain; Depression; Humans; Imagery, Psychotherapy; Male; Motivation; Opioid-Related Disorders; Photic Stimulation; Psychiatric Status Rating Scales; Reward | 2019 |
Behavioral preference for viewing drug
Topics: Adult; Aged; Allostasis; Analgesics, Opioid; Choice Behavior; Chronic Pain; Cross-Sectional Studies; Disease Susceptibility; Female; Humans; Longitudinal Studies; Male; Middle Aged; Opioid-Related Disorders; Pattern Recognition, Visual; Pleasure; Prognosis; Reward | 2020 |
Community opioid treatment perspectives on contingency management: perceived feasibility, effectiveness, and transportability of social and financial incentives.
Topics: Adult; Attitude of Health Personnel; Community Health Services; Data Collection; Feasibility Studies; Female; Health Personnel; Humans; Male; Middle Aged; Models, Theoretical; Opioid-Related Disorders; Patient Satisfaction; Quality of Life; Reinforcement, Psychology; Reward | 2013 |
Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET.
Topics: Adult; Aged; Analgesics, Opioid; Anticipation, Psychological; Buprenorphine; Corpus Striatum; Dopamine; Dopamine Antagonists; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Positron-Emission Tomography; Raclopride; Reward; Young Adult | 2014 |
Opiate exposure and withdrawal induces a molecular memory switch in the basolateral amygdala between ERK1/2 and CaMKIIα-dependent signaling substrates.
Topics: Amygdala; Analysis of Variance; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Conditioning, Operant; Dopamine Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Memory; Mitogen-Activated Protein Kinase 3; Morphine; Narcotics; Opioid-Related Disorders; Phosphorylation; Rats; Rats, Sprague-Dawley; Reward; Signal Transduction; Ventral Tegmental Area | 2013 |
Extinction of opiate reward reduces dendritic arborization and c-Fos expression in the nucleus accumbens core.
Topics: Animals; Conditioning, Classical; Dendrites; Dendritic Spines; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mice; Mice, Inbred C57BL; Morphine; Narcotics; Nucleus Accumbens; Opioid-Related Disorders; Proto-Oncogene Proteins c-fos; Reward; Space Perception; Substance Withdrawal Syndrome | 2014 |
Effects of Mindfulness-Oriented Recovery Enhancement on reward responsiveness and opioid cue-reactivity.
Topics: Adult; Affect; Arousal; Attention; Chronic Pain; Cues; Female; Heart Rate; Humans; Male; Middle Aged; Mindfulness; Opioid-Related Disorders; Prescription Drug Misuse; Reward; Self Report | 2014 |
The antipsychotic aripiprazole selectively prevents the stimulant and rewarding effects of morphine in mice.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Central Nervous System Stimulants; Conditioning, Psychological; Disease Models, Animal; Male; Mice; Morphine; Motor Activity; Nociception; Opioid-Related Disorders; Piperazines; Quinolones; Reward | 2014 |
Personality as a risk factor for illicit opioid use and a protective factor for illicit opioid dependence.
Topics: Adult; Female; Harm Reduction; Humans; Illicit Drugs; Male; Middle Aged; Opioid-Related Disorders; Personality; Personality Inventory; Protective Factors; Reward; Risk Factors; Temperament | 2014 |
Allostatic dysregulation of natural reward processing in prescription opioid misuse: autonomic and attentional evidence.
Topics: Adult; Allostasis; Analgesics, Opioid; Attention; Chronic Pain; Cues; Female; Heart Rate; Humans; Male; Middle Aged; Neuropsychological Tests; Opioid-Related Disorders; Prescription Drug Misuse; Reward | 2015 |
Pharmacotherapy: Quest for the quitting pill.
Topics: Animals; Behavior, Addictive; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clinical Trials as Topic; Cocaine-Related Disorders; Counseling; Dopamine; Drug Discovery; Drug Industry; Humans; Ibogaine; Lobeline; Molecular Targeted Therapy; Naloxone; Naltrexone; Oligopeptides; Opioid-Related Disorders; Pleasure; Rats; Receptors, Nicotinic; Reward; Substance-Related Disorders; Tobacco Use Disorder; Vaccines; Vesicular Monoamine Transport Proteins | 2015 |
Probabilistic reward- and punishment-based learning in opioid addiction: Experimental and computational data.
Topics: Adult; Decision Making; Female; Humans; Male; Middle Aged; Opioid-Related Disorders; Probability Learning; Punishment; Reward | 2016 |
Evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence.
Topics: Adult; Anhedonia; Brain Mapping; Case-Control Studies; Cues; Emotions; Female; Humans; Magnetic Resonance Imaging; Male; Opioid-Related Disorders; Prefrontal Cortex; Reward; Spectroscopy, Near-Infrared; Substance Withdrawal Syndrome | 2016 |
A thalamic input to the nucleus accumbens mediates opiate dependence.
Topics: Animals; Avoidance Learning; Disease Models, Animal; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Morphine; Neural Pathways; Neuronal Plasticity; Neurons; Nucleus Accumbens; Opioid-Related Disorders; Optogenetics; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Reward; Substance Withdrawal Syndrome; Synaptic Transmission; Thalamus | 2016 |
Temporal preference in individuals reporting chronic pain: discounting of delayed pain-related and monetary outcomes.
Topics: Adult; Aged; Analgesics, Opioid; Behavior, Addictive; Choice Behavior; Chronic Pain; Delay Discounting; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Opioid-Related Disorders; Reward | 2016 |
Examining the interaction between cognitive control and reward sensitivity in substance use dependence.
Topics: Adult; Cognition; Cues; Female; Humans; Inhibition, Psychological; Internal-External Control; Male; Middle Aged; Opioid-Related Disorders; Reference Values; Reward; Young Adult | 2016 |
Morphine treatment enhances glutamatergic input onto neurons of the nucleus accumbens via both disinhibitory and stimulating effect.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Glutamic Acid; Male; Morphine; Neurons; Nucleus Accumbens; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reward; Synaptic Transmission | 2017 |
Learning and generalization from reward and punishment in opioid addiction.
Topics: Adult; Analysis of Variance; Association Learning; Case-Control Studies; Female; Generalization, Psychological; Humans; Male; Middle Aged; Opioid-Related Disorders; Punishment; Retention, Psychology; Reward; Young Adult | 2017 |
Deficits in autonomic indices of emotion regulation and reward processing associated with prescription opioid use and misuse.
Topics: Adult; Analgesics, Opioid; Autonomic Nervous System; Chronic Pain; Emotions; Female; Heart Rate; Humans; Male; Middle Aged; Morphine; Opioid-Related Disorders; Reward; Self Report | 2017 |
Lorcaserin Suppresses Oxycodone Self-Administration and Relapse Vulnerability in Rats.
Topics: Aminopyridines; Animals; Behavior, Animal; Benzazepines; Conditioning, Operant; Cues; Indoles; Male; Opioid-Related Disorders; Oxycodone; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2017 |
Neurobiological substrates of cue-elicited craving and anhedonia in recently abstinent opioid-dependent males.
Topics: Adult; Brain; Brain Chemistry; Cerebral Cortex; Cues; Data Interpretation, Statistical; Female; Humans; Image Processing, Computer-Assisted; Individuality; Limbic System; Magnetic Resonance Imaging; Male; Middle Aged; Motivation; Opioid-Related Disorders; Oxygen; Photic Stimulation; Psychiatric Status Rating Scales; Reward; Substance Abuse Detection | 2009 |
RGS9-2: probing an intracellular modulator of behavior as a drug target.
Topics: Animals; Antiparkinson Agents; Antipsychotic Agents; Central Nervous System Stimulants; Dyskinesia, Drug-Induced; Humans; Opioid-Related Disorders; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; Receptors, Opioid, mu; Reward; RGS Proteins; Signal Transduction | 2009 |
Ventral tegmental area BDNF induces an opiate-dependent-like reward state in naive rats.
Topics: Animals; Bicuculline; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Dopamine; Dopamine Antagonists; Flupenthixol; GABA Agonists; GABA Antagonists; Heroin Dependence; Male; Morphine; Muscimol; Opioid-Related Disorders; Rats; Rats, Wistar; Receptors, GABA-A; Reward; RNA, Messenger; Signal Transduction; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2009 |
Comparison of the antinociceptive and antirewarding profiles of novel bifunctional nociceptin receptor/mu-opioid receptor ligands: implications for therapeutic applications.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; CHO Cells; Conditioning, Classical; Cricetinae; Cricetulus; Humans; Ligands; Male; Mice; Mice, Inbred ICR; Molecular Structure; Nociceptin Receptor; Opioid-Related Disorders; Pain; Protein Binding; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, mu; Reward; Transfection | 2009 |
Periaqueductal gray afferents synapse onto dopamine and GABA neurons in the rat ventral tegmental area.
Topics: Animals; Brain Mapping; Dopamine; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Limbic System; Male; Microscopy, Immunoelectron; Motivation; Neural Inhibition; Neural Pathways; Neuroanatomical Tract-Tracing Techniques; Neuropeptides; Opioid-Related Disorders; Periaqueductal Gray; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Reward; Secretory Vesicles; Synapses; Synaptic Transmission; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2010 |
NMDA receptor hypofunction in the prelimbic cortex increases sensitivity to the rewarding properties of opiates via dopaminergic and amygdalar substrates.
Topics: Amygdala; Analgesics, Opioid; Animals; Conditioning, Operant; Disease Models, Animal; Dopamine; Glutamic Acid; Male; Opioid-Related Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward | 2011 |
Neuropathic and chronic pain stimuli downregulate central mu-opioid and dopaminergic transmission.
Topics: Analgesics, Opioid; Chronic Disease; Down-Regulation; Dynorphins; Endorphins; Extracellular Signal-Regulated MAP Kinases; Humans; Neuralgia; Opioid-Related Disorders; Pain; Protein Kinase C; Receptors, Dopamine; Receptors, Opioid, mu; Reward; Up-Regulation; Ventral Tegmental Area | 2010 |
Intrathecal delivery of a mutant micro-opioid receptor activated by naloxone as a possible antinociceptive paradigm.
Topics: Animals; Conditioning, Operant; Drug Tolerance; Gene Transfer Techniques; Genetic Therapy; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Mutation; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Pain Management; Pain Measurement; Receptors, Opioid, mu; Reward; Subarachnoid Space | 2010 |
Hypothetical intertemporal choice and real economic behavior: delay discounting predicts voucher redemptions during contingency-management procedures.
Topics: Adult; Age Factors; Analgesics, Opioid; Buprenorphine; Choice Behavior; Female; Humans; Income; Male; Opiate Substitution Treatment; Opioid-Related Disorders; Reward; Substance Abuse Detection; Time Factors; Token Economy; Young Adult | 2010 |
Risky decision-making predicts short-term outcome of community but not residential treatment for opiate addiction. Implications for case management.
Topics: Adult; Ambulatory Care; Case Management; Decision Making; Female; Follow-Up Studies; Gambling; Humans; Impulsive Behavior; Male; Middle Aged; Opioid-Related Disorders; Psychiatric Status Rating Scales; Residential Treatment; Reward; Risk-Taking; Software; Time Factors; Treatment Outcome; Young Adult | 2011 |
Acquisition, extinction, and recall of opiate reward memory are signaled by dynamic neuronal activity patterns in the prefrontal cortex.
Topics: Analgesics, Opioid; Animals; Conditioning, Classical; Electrophysiology; Extinction, Psychological; Male; Memory; Morphine; Neurons; Opioid-Related Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward | 2011 |
Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Compulsive Behavior; Conditioning, Psychological; Drug-Seeking Behavior; Gene Knock-In Techniques; Humans; Mice; Morphine; Neuropsychological Tests; Opioid-Related Disorders; Rats; Receptors, Opioid, mu; Recurrence; Reward; Substance-Related Disorders | 2011 |
Delay discounting, impulsiveness, and addiction severity in opioid-dependent patients.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Behavior, Addictive; Computers; Disease Progression; Female; Humans; Illicit Drugs; Impulsive Behavior; Intelligence Tests; Male; Methadone; Middle Aged; Opioid-Related Disorders; Psychiatric Status Rating Scales; Reward; Smoking; Software; Substance Abuse Treatment Centers; Substance-Related Disorders; Surveys and Questionnaires; Time Factors; Urinalysis; Young Adult | 2011 |
Identification of a dopamine receptor-mediated opiate reward memory switch in the basolateral amygdala-nucleus accumbens circuit.
Topics: Action Potentials; Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Benzazepines; Conditioning, Operant; Cyclic AMP; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Memory; Morphine; Nucleus Accumbens; Opioid-Related Disorders; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Opioid; Reward; Salicylamides; Thionucleotides | 2011 |
Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential?
Topics: Affect; Animals; Behavior, Addictive; Brain; Buprenorphine; Dopamine; Dopaminergic Neurons; Glucose; Humans; Hypothalamus; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Opioid-Related Disorders; Recurrence; Reward; Substantia Nigra; Treatment Outcome | 2011 |
Olanzapine suppresses the rewarding and discriminative stimulus effects induced by morphine.
Topics: Analgesics, Opioid; Animals; Antipsychotic Agents; Benzodiazepines; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Morphine; Olanzapine; Opioid-Related Disorders; Rats; Rats, Inbred F344; Reward | 2012 |
Inputs from the basolateral amygdala to the nucleus accumbens shell control opiate reward magnitude via differential dopamine D1 or D2 receptor transmission.
Topics: Amygdala; Analgesics, Opioid; Animals; Conditioning, Classical; Male; Mice; Morphine; Neural Pathways; Nucleus Accumbens; Opioid-Related Disorders; Patch-Clamp Techniques; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2012 |
The effects of exogenous CCK-8 on the acquisition and expression of morphine-induced CPP.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Morphine; Motor Activity; Opioid-Related Disorders; Rats; Rats, Wistar; Reward; Sincalide; Substance Withdrawal Syndrome | 2012 |
Effects of a Rhodiola rosea L. extract on the acquisition, expression, extinction, and reinstatement of morphine-induced conditioned place preference in mice.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Injections, Intraperitoneal; Male; Mice; Morphine; Opioid-Related Disorders; Plant Extracts; Reinforcement Schedule; Reward; Rhodiola; Secondary Prevention | 2012 |
The heritability of oxycodone reward and concomitant phenotypes in a LG/J × SM/J mouse advanced intercross line.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Operant; Drug-Seeking Behavior; Female; Genetic Predisposition to Disease; Likelihood Functions; Male; Mice; Mice, Inbred Strains; Motor Activity; Opioid-Related Disorders; Oxycodone; Phenotype; Reward; Sodium Chloride | 2014 |
Mild opioid deprivation increases the degree that opioid-dependent outpatients discount delayed heroin and money.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Female; Heroin; Humans; Male; Middle Aged; Opioid-Related Disorders; Outpatients; Reinforcement Schedule; Reward | 2002 |
Altered motivation and learning following opiate withdrawal: evidence for prolonged dysregulation of reward processing.
Topics: Animals; Conditioning, Operant; Male; Morphine; Motivation; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Substance Withdrawal Syndrome | 2003 |
Opiate state controls bi-directional reward signaling via GABAA receptors in the ventral tegmental area.
Topics: Animals; Bicuculline; Carbonic Anhydrases; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Dopamine; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Heroin; Injections, Intraventricular; Male; Muscimol; Narcotics; Opioid-Related Disorders; Rats; Rats, Wistar; Receptors, GABA-A; Reward; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2004 |
Brain reward deficits accompany naloxone-precipitated withdrawal from acute opioid dependence.
Topics: Acute Disease; Animals; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome | 2004 |
GABAA receptors signal bidirectional reward transmission from the ventral tegmental area to the tegmental pedunculopontine nucleus as a function of opiate state.
Topics: Animals; Bicuculline; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Muscimol; Opioid-Related Disorders; Pedunculopontine Tegmental Nucleus; Rats; Rats, Wistar; Receptors, GABA-A; Reward; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area | 2004 |
Characterization of GalR1, GalR2, and GalR3 immunoreactivity in catecholaminergic nuclei of the mouse brain.
Topics: Animals; Brain; Catecholamines; Galanin; Immunohistochemistry; Locus Coeruleus; Mice; Neural Pathways; Neurons; Nucleus Accumbens; Opioid-Related Disorders; Receptor, Galanin, Type 1; Receptor, Galanin, Type 2; Receptor, Galanin, Type 3; Receptors, Galanin; Reward; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2004 |
Ultra-low-dose naltrexone suppresses rewarding effects of opiates and aversive effects of opiate withdrawal in rats.
Topics: Animals; Avoidance Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Female; Injections, Subcutaneous; Morphine Dependence; Motivation; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Orientation; Oxycodone; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome | 2005 |
Severe deficit in brain reward function associated with fentanyl withdrawal in rats.
Topics: Affect; Animals; Brain; Dose-Response Relationship, Drug; Fentanyl; Male; Medial Forebrain Bundle; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, mu; Reward; Self Stimulation; Sensory Thresholds; Substance Withdrawal Syndrome | 2006 |
An essential role for DeltaFosB in the nucleus accumbens in morphine action.
Topics: Animals; Blotting, Western; Dynorphins; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Transgenic; Morphine; Narcotics; Nucleus Accumbens; Opioid-Related Disorders; Proto-Oncogene Proteins c-fos; Reward | 2006 |
The relationship between temporal discounting and the prisoner's dilemma game in intranasal abusers of prescription opioids.
Topics: Administration, Intranasal; Adult; Buprenorphine; Cooperative Behavior; Drug Prescriptions; Female; Humans; Impulsive Behavior; Male; Narcotic Antagonists; Opioid-Related Disorders; Prisoners; Reward; Self Efficacy; Token Economy | 2007 |
Opiate withdrawal modifies synaptic plasticity in subicular-nucleus accumbens pathway in vivo.
Topics: Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Memory; Morphine; Narcotics; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome; Synaptic Transmission | 2007 |
Place conditioning in a two- or three-conditioning compartment apparatus: a comparative study with morphine and U-50,488.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Association Learning; Avoidance Learning; Conditioning, Classical; Male; Mental Recall; Morphine; Motivation; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reward; Social Environment | 2007 |
Chronic cocaine but not chronic amphetamine use is associated with perseverative responding in humans.
Topics: Adolescent; Adult; Aged; Amphetamine; Amphetamine-Related Disorders; Appetitive Behavior; Association Learning; Central Nervous System Stimulants; Choice Behavior; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Humans; Male; Middle Aged; Motivation; Opioid-Related Disorders; Probability Learning; Receptors, Serotonin; Reversal Learning; Reward; Stereotyped Behavior | 2008 |
Opiate receptors and endogenous opiates: panorama of opiate research.
Topics: Acupuncture Therapy; Afferent Pathways; Animals; Brain; Endorphins; Euphoria; Humans; Learning; Mental Recall; Neurotransmitter Agents; Nociceptors; Opioid-Related Disorders; Pain; Receptors, Opioid; Reward; Schizophrenia; Spinal Cord; Stress, Physiological | 1982 |
Biobehavioral bases of the reinforcing properties of opiate drugs.
Topics: Animals; Brain; Chlorpromazine; Drug Tolerance; Electric Stimulation; Humans; Morphine; Naloxone; Narcotics; Opioid-Related Disorders; Rats; Reinforcement, Psychology; Reward; Self Stimulation; Sensory Thresholds | 1982 |
Neurochemical mechanisms underlying responses to psychostimulants.
Topics: Animals; Behavior; Brain; Brain Chemistry; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Humans; Methylphenidate; Opioid-Related Disorders; Raclopride; Receptors, Dopamine; Research Design; Reward; Salicylamides; Substance-Related Disorders | 1996 |
Inhibition of nitric oxide synthesis reduces intravenous cocaine self-administration in the rat.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Opioid-Related Disorders; Rats; Rats, Wistar; Reward; Self Administration | 1996 |
Prenatal morphine enhances morphine-conditioned place preference in adult rats.
Topics: Animals; Conditioning, Psychological; Female; Maternal Exposure; Morphine; Narcotics; Opioid-Related Disorders; Pregnancy; Rats; Rats, Inbred F344; Reward; Task Performance and Analysis | 1997 |
The D2 receptor is critical in mediating opiate motivation only in opiate-dependent and withdrawn mice.
Topics: Animals; Brain; Conditioning, Psychological; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motivation; Narcotics; Opioid-Related Disorders; Receptors, Dopamine D2; Reward; Substance Withdrawal Syndrome | 2001 |
Plasmalemmal mu-opioid receptor distribution mainly in nondopaminergic neurons in the rat ventral tegmental area.
Topics: Animals; Cell Membrane; Cytoplasm; Dendrites; Dopamine; Immunohistochemistry; Male; Mice; Microscopy, Electron; Nerve Fibers, Myelinated; Neurons; Opioid-Related Disorders; Presynaptic Terminals; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2001 |
Changes in reward-induced brain activation in opiate addicts.
Topics: Adult; Brain; Brain Mapping; Cerebrovascular Circulation; Emotions; Feedback, Psychological; Functional Laterality; Heart Rate; Humans; Male; Narcotics; Neural Pathways; Neuropsychological Tests; Opioid-Related Disorders; Photic Stimulation; Psychomotor Performance; Reward; Tomography, Emission-Computed | 2001 |
The effects of delayed rewards, social pressure, and frustration on the responses of opiate addicts.
Topics: Adolescent; Adult; Ethnicity; Female; Frustration; Humans; Juvenile Delinquency; Male; Opioid-Related Disorders; Personality Tests; Reward; Social Adjustment | 1979 |
Opiate dependence alters central reward of nalbuphine or pentazocine plus tripelennamine.
Topics: Animals; Brain; Electric Stimulation; Electrodes, Implanted; Male; Morphinans; Nalbuphine; Opioid-Related Disorders; Pentazocine; Rats; Rats, Inbred F344; Reward; Tripelennamine | 1989 |