s-methylisothiopseudouronium has been researched along with Shock, Septic in 9 studies
S-methylisothiopseudouronium: inhibits nitric oxide synthase; structure in first source
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "NOS inhibitors combined with cathecholamines were thus suggested to be able to reduce the cathecolamine dosage in patients suffering from septic shock; They are thus considered to be hemodynamically effective agents." | 1.33 | Reinforcement therapy using nitric oxide synthase inhibitors against endotoxin shock in dogs. ( Deguchi, Y; Fukuda, M; Imamura, Y; Miyoshi, N; Nakagawa, T; Soga, Y; Suga, H; Suzuki, T, 2006) |
| "Endotoxic shock was induced by Escherichia coli endotoxin in both control (n = 8) and SMT groups (n = 8)." | 1.29 | [Effects of selective nitric oxide synthase inhibitor in sheep with endotoxic shock]. ( Chen, D; Liu, D; Qiu, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khromov, OS | 1 |
| Ivanova, IV | 1 |
| Stefanov, OV | 1 |
| Suga, H | 1 |
| Nakagawa, T | 1 |
| Soga, Y | 1 |
| Deguchi, Y | 1 |
| Suzuki, T | 1 |
| Miyoshi, N | 1 |
| Imamura, Y | 1 |
| Fukuda, M | 1 |
| Ehrentraut, S | 1 |
| Frede, S | 1 |
| Stapel, H | 1 |
| Mengden, T | 1 |
| Grohé, C | 1 |
| Fandrey, J | 1 |
| Meyer, R | 1 |
| Baumgarten, G | 1 |
| Szabó, C | 1 |
| Southan, GJ | 1 |
| Thiemermann, C | 1 |
| Liu, D | 1 |
| Chen, D | 1 |
| Qiu, H | 1 |
| Rosselet, A | 1 |
| Feihl, F | 1 |
| Markert, M | 1 |
| Gnaegi, A | 1 |
| Perret, C | 1 |
| Liaudet, L | 1 |
| Mitaka, C | 1 |
| Hirata, Y | 1 |
| Masaki, Y | 1 |
| Takei, T | 1 |
| Yokoyama, K | 1 |
| Imai, T | 1 |
| Cohen, RI | 2 |
| Shapir, Y | 1 |
| Davis, A | 1 |
| Loona, R | 1 |
| Scharf, SM | 2 |
| Hassell, AM | 1 |
| Marzouk, K | 1 |
| Marini, C | 1 |
| Liu, SF | 1 |
9 other studies available for s-methylisothiopseudouronium and Shock, Septic
| Article | Year |
|---|---|
[Inhibition of nitric oxide synthesis during bacterial shock does not prevent development of resistant hypotension and death in rats].
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypotension; Isot | 2005 |
Reinforcement therapy using nitric oxide synthase inhibitors against endotoxin shock in dogs.
Topics: Animals; Catecholamines; Dogs; Endotoxins; Enzyme Inhibitors; Isothiuronium; Models, Animal; Nitric | 2006 |
Antagonism of lipopolysaccharide-induced blood pressure attenuation and vascular contractility.
Topics: Animals; Aorta; Blood Pressure; Cytokines; Disaccharides; Disease Models, Animal; Dose-Response Rela | 2007 |
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Esche | 1994 |
[Effects of selective nitric oxide synthase inhibitor in sheep with endotoxic shock].
Topics: Animals; Blood Pressure; Hemodynamics; Isothiuronium; Nitric Oxide Synthase; Oxygen Consumption; Ran | 1996 |
Selective iNOS inhibition is superior to norepinephrine in the treatment of rat endotoxic shock.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluati | 1998 |
S-Methylisothiourea sulfate improves renal, but not hepatic dysfunction in canine endotoxic shock model.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Enzyme Inhibitors; Hemodynamics; Isothiur | 2000 |
Comparison between selective and nonselective nitric oxide synthase inhibition and phenylephrine in normal and endotoxic swine.
Topics: Animals; Cardiotonic Agents; Enzyme Inhibitors; Female; Hemodynamics; Isothiuronium; Lipopolysacchar | 2000 |
Renal effects of nitric oxide in endotoxemia.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Disease Models, | 2001 |