s-methylisothiopseudouronium has been researched along with Osteoarthritis in 3 studies
S-methylisothiopseudouronium: inhibits nitric oxide synthase; structure in first source
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "SMT significantly reduced GAGs, hydroxyproline, matrix metalloproteinase (MMP)-13, tumour necrosis factor alpha (TNF-α), prostaglindin E2 (PGE2 ) and nitrite release in stimulated rabbit cartilage media indicating chondroprotective and anti-inflammatory effects of SMT in osteoarthritis (OA)." | 3.80 | Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis. ( Balaganur, V; Kumar, D; Kumari, RR; Latief, N; Lingaraju, MC; More, AS; Pathak, NN; Tandan, SK, 2014) |
| "Osteoarthritis was produced by single intra-articular injection of the MIA in the right knee joint on day 0." | 1.39 | Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. ( Balaganur, V; Gupta, G; Kumar, D; Kumari, RR; Lingaraju, MC; More, AS; Pathak, NN; Sharma, AK; Tandan, SK, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balaganur, V | 2 |
| Pathak, NN | 2 |
| Lingaraju, MC | 2 |
| More, AS | 2 |
| Latief, N | 1 |
| Kumari, RR | 2 |
| Kumar, D | 3 |
| Tandan, SK | 2 |
| Gupta, G | 1 |
| Sharma, AK | 1 |
| Bian, CR | 1 |
| Li, DR | 1 |
3 other studies available for s-methylisothiopseudouronium and Osteoarthritis
| Article | Year |
|---|---|
Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Chondrocytes; Cytokines; Enzyme Inhibitors; | 2014 |
Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intra-Articular; Iodo | 2013 |
[Animal experimental study of intra-articular injection of S-methylisothiourea for treatment of temporomandibular joint osteoarthrosis].
Topics: Animals; Injections, Intra-Articular; Isothiuronium; Osteoarthritis; Temporomandibular Joint; Tempor | 2007 |