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s-methylisothiopseudouronium and Inflammation

s-methylisothiopseudouronium has been researched along with Inflammation in 9 studies

S-methylisothiopseudouronium: inhibits nitric oxide synthase; structure in first source

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"SMT significantly reduced GAGs, hydroxyproline, matrix metalloproteinase (MMP)-13, tumour necrosis factor alpha (TNF-α), prostaglindin E2 (PGE2 ) and nitrite release in stimulated rabbit cartilage media indicating chondroprotective and anti-inflammatory effects of SMT in osteoarthritis (OA)."3.80Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis. ( Balaganur, V; Kumar, D; Kumari, RR; Latief, N; Lingaraju, MC; More, AS; Pathak, NN; Tandan, SK, 2014)
"Carrageenan-induced hyperalgesia was evaluated by measuring the withdrawal response to mechanical stimuli, using an electronic version of the von Frey anesthesiometer in Wistar rats."1.40Nitric oxide synthase modulates the antihyperalgesic effect of the NMDA receptor antagonist MK-801 on Carrageenan-induced inflammatory pain in rats. ( Prostran, MS; Savic Vujovic, KR; Srebro, DP; Vucković, SM, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Srebro, DP2
Vučković, S1
Milovanović, A1
Vujović, KS1
Vučetić, Č1
Prostran, M1
Balaganur, V1
Pathak, NN1
Lingaraju, MC1
More, AS1
Latief, N1
Kumari, RR1
Kumar, D1
Tandan, SK1
Xiao, L1
Liu, W1
Li, J1
Xie, Y1
He, M1
Fu, J1
Jin, W1
Shao, C1
Vucković, SM1
Savic Vujovic, KR1
Prostran, MS1
Kunak, ZI1
Macit, E1
Yaren, H1
Yaman, H1
Cakir, E1
Aydin, I1
Turker, T1
Kurt, YG1
Ozcan, A1
Uysal, B1
Isbilir, S1
Akgul, EO1
Cayci, T1
Korkmaz, A1
Kenar, L1
Wildhirt, SM1
Dudek, RR1
Suzuki, H1
Bing, RJ1
Iuvone, T1
Van Osselaer, N1
D'Acquisto, F1
Carnuccio, R1
Herman, AG1
Hsueh, W1
Tan, XD1
Qu, XW1
Sun, XM1
Gonzalez-Crussi, F1
Vos, TA1
Gouw, AS1
Klok, PA1
Havinga, R1
van Goor, H1
Huitema, S1
Roelofsen, H1
Kuipers, F1
Jansen, PL1
Moshage, H1

Reviews

1 review available for s-methylisothiopseudouronium and Inflammation

ArticleYear
Involvement of inducible nitric oxide synthase in the inflammatory process of myocardial infarction.
    International journal of cardiology, 1995, Volume: 50, Issue:3

    Topics: Animals; Apoptosis; Coronary Circulation; Enzyme Induction; Enzyme Inhibitors; Humans; Immunohistoch

1995

Other Studies

8 other studies available for s-methylisothiopseudouronium and Inflammation

ArticleYear
Preventive treatment with dizocilpine attenuates oedema in a carrageenan model of inflammation: the interaction of glutamatergic and nitrergic signaling.
    Inflammopharmacology, 2019, Volume: 27, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arginine; Carrageenan; Dizocilpine Maleate; Edema; Inflammation;

2019
Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Chondrocytes; Cytokines; Enzyme Inhibitors;

2014
Irradiated U937 cells trigger inflammatory bystander responses in human umbilical vein endothelial cells through the p38 pathway.
    Radiation research, 2014, Volume: 182, Issue:1

    Topics: Atherosclerosis; Benzoates; Bystander Effect; Coculture Techniques; Human Umbilical Vein Endothelial

2014
Nitric oxide synthase modulates the antihyperalgesic effect of the NMDA receptor antagonist MK-801 on Carrageenan-induced inflammatory pain in rats.
    The Tohoku journal of experimental medicine, 2014, Volume: 234, Issue:4

    Topics: Animals; Arginine; Carrageenan; Dizocilpine Maleate; Hyperalgesia; Inflammation; Isothiuronium; Male

2014
Protective effects of melatonin and S-methylisothiourea on mechlorethamine induced nephrotoxicity.
    The Journal of surgical research, 2012, Jun-01, Volume: 175, Issue:1

    Topics: Animals; Chemical Warfare Agents; Disease Models, Animal; Inflammation; Isothiuronium; Kidney Diseas

2012
Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Animals; Arginine; Capillary Permeability; Carrageenan; Cell Movement; Enzyme Inhibitors; Epoprosten

1997
Injurious and protective mechanisms in the gut. Interaction of PAF, phospholipase A2, eicosanoids, and nitric oxide synthase.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: Animals; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Group II Phospholipases A2; Guanidines;

1997
Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats.
    Gastroenterology, 1997, Volume: 113, Issue:4

    Topics: Amino Acid Sequence; Animals; Antibodies; Bile; Bile Canaliculi; Bile Ducts; Endotoxemia; Endotoxins

1997