s-methylisothiopseudouronium has been researched along with Disease Models, Animal in 33 studies
S-methylisothiopseudouronium: inhibits nitric oxide synthase; structure in first source
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to evaluate whether the administration of s-methylisothiourea and melatonin has protective potential in intestinal ischemia/reperfusion injury." | 7.76 | Evaluation of effects of s-methyl isothiourea and melatonin on intestinal ischemia/reperfusion injury in rats. ( Atabek, C; Demirin, H; Karaoglu, A; Kesik, V; Korkmaz, A; Kul, M; Ozler, M; Oztas, E; Sadir, S; Temiz, A; Tunc, T, 2010) |
| "The present study was designed to evaluate whether the administration of s-methylisothiourea and melatonin has protective potential in intestinal ischemia/reperfusion injury." | 3.76 | Evaluation of effects of s-methyl isothiourea and melatonin on intestinal ischemia/reperfusion injury in rats. ( Atabek, C; Demirin, H; Karaoglu, A; Kesik, V; Korkmaz, A; Kul, M; Ozler, M; Oztas, E; Sadir, S; Temiz, A; Tunc, T, 2010) |
| "The dose-response relation of S-methylisothiourea, rofecoxib, mefenamic acid, and their combination was studied in the late phase of formalin-induced pain in mice over the time spent in licking the hindpaw after formalin injection." | 3.74 | The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study. ( Bhat, AS; Krishna, V; Kumar, D; Prakash, VR; Tandan, SK, 2008) |
| " To determine whether endotoxemic cardiac contractile dysfunction involves NOS, the present study used a rat model of endotoxemia without shock and examined the effects of glucocorticoids (dexamethasone, a potent inhibitor of inducible NOS, iNOS, expression), isoform nonselective NOS inhibitor (NG-monomethyl-L-arginine, L-NMA) and iNOS selective inhibitor (S-methylisothiourea sulfate, SMT) on cardiac contractile dysfunction." | 3.69 | Nitric oxide synthase is not involved in cardiac contractile dysfunction in a rat model of endotoxemia without shock. ( Ao, L; Banerjee, A; Brown, JM; Fullerton, DA; Harken, AH; Meng, X, 1997) |
| "Osteoarthritis was produced by single intra-articular injection of the MIA in the right knee joint on day 0." | 1.39 | Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. ( Balaganur, V; Gupta, G; Kumar, D; Kumari, RR; Lingaraju, MC; More, AS; Pathak, NN; Sharma, AK; Tandan, SK, 2013) |
| "Ocular hypertension was induced by unilaterally cauterizing three episcleral vessels and the unoperated eye served as control." | 1.37 | Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. ( Aslan, M; Batinic-Haberle, I; Cort, A; Dogan, S; Ozturk, N; Spasojevic, I; Unal, M; Yargicoglu, P, 2011) |
| "Acute pancreatitis was induced in Group I and Group II by injection of taurocholate and trypsin into the common biliopancreatic duct." | 1.31 | Inhibition of inducible nitric oxide synthase reduces bacterial translocation in a rat model of acute pancreatitis. ( Basustaoglu, A; Comert, B; Deveci, S; Kocabalkan, F; Mas, MR; Ozyurt, M; Refik, M; Saglamkaya, U; Simsek, I; Yasar, M, 2001) |
| " Long-term administration (2 mo) of the selective NOS II inhibitor S-methylisothiourea (SMT) to rats with MI significantly improved cardiac function." | 1.31 | Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure. ( Fahas, L; Giaid, A; Hu, F; Saito, T; Shennib, H; Tayara, L, 2002) |
| "In a model of volume-controlled hemorrhagic shock in rats, invariably leading to death within 30 min of bleeding termination, the intravenous (i." | 1.30 | Inhibition of nitric oxide synthases enhances the effect of ACTH in hemorrhagic shock. ( Bazzani, C; Bertolini, A; Guarini, S, 1997) |
| "Myocardial infarction was induced by ligation of the left anterior descending coronary artery (LAD), and tissue was collected at selected times thereafter from both ligated and sham-operated rats." | 1.30 | Reduction of myocardial infarct size by inhibition of inducible nitric oxide synthase. ( Carretero, OA; LaPointe, MC; Liu, YH; Wang, D; Yang, XP, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 16 (48.48) | 29.6817 |
| 2010's | 9 (27.27) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Zheng, L | 1 |
| Ding, J | 1 |
| Wang, J | 2 |
| Zhou, C | 1 |
| Zhang, W | 1 |
| Srebro, D | 1 |
| Vučković, S | 1 |
| Prostran, M | 1 |
| Guzel, A | 2 |
| Basaran, UN | 1 |
| Aksu, B | 1 |
| Kanter, M | 1 |
| Yalcin, O | 1 |
| Aktas, C | 1 |
| Karasalihoglu, S | 1 |
| Guven, A | 1 |
| Uysal, B | 2 |
| Akgul, O | 1 |
| Cermik, H | 1 |
| Gundogdu, G | 1 |
| Surer, I | 1 |
| Ozturk, H | 1 |
| Korkmaz, A | 4 |
| ArunaDevi, R | 1 |
| Ramteke, VD | 1 |
| Kumar, S | 1 |
| Shukla, MK | 1 |
| Jaganathan, S | 1 |
| Kumar, D | 4 |
| Sharma, AK | 2 |
| Tandan, SK | 3 |
| Tunc, T | 1 |
| Demirin, H | 1 |
| Karaoglu, A | 1 |
| Kesik, V | 1 |
| Temiz, A | 1 |
| Ozler, M | 1 |
| Sadir, S | 1 |
| Atabek, C | 1 |
| Kul, M | 1 |
| Oztas, E | 2 |
| Dogan, S | 1 |
| Unal, M | 1 |
| Ozturk, N | 1 |
| Yargicoglu, P | 1 |
| Cort, A | 1 |
| Spasojevic, I | 1 |
| Batinic-Haberle, I | 1 |
| Aslan, M | 1 |
| Pintado, C | 1 |
| Revilla, E | 1 |
| Vizuete, ML | 1 |
| Jiménez, S | 1 |
| García-Cuervo, L | 1 |
| Vitorica, J | 1 |
| Ruano, D | 1 |
| Castaño, A | 1 |
| Kunak, ZI | 1 |
| Macit, E | 1 |
| Yaren, H | 1 |
| Yaman, H | 1 |
| Cakir, E | 1 |
| Aydin, I | 1 |
| Turker, T | 1 |
| Kurt, YG | 1 |
| Ozcan, A | 1 |
| Isbilir, S | 1 |
| Akgul, EO | 1 |
| Cayci, T | 1 |
| Kenar, L | 1 |
| More, AS | 1 |
| Kumari, RR | 1 |
| Gupta, G | 1 |
| Lingaraju, MC | 1 |
| Balaganur, V | 1 |
| Pathak, NN | 1 |
| Sun, W | 2 |
| Jin, DD | 1 |
| Wang, JX | 1 |
| Qin, LY | 1 |
| Liu, XX | 1 |
| Oter, S | 1 |
| Yildirim, I | 1 |
| Topal, T | 1 |
| Bilgic, H | 1 |
| Khromov, OS | 1 |
| Ivanova, IV | 1 |
| Stefanov, OV | 1 |
| Jiang, X | 1 |
| Shi, E | 1 |
| Nakajima, Y | 1 |
| Sato, S | 1 |
| Ehrentraut, S | 1 |
| Frede, S | 1 |
| Stapel, H | 1 |
| Mengden, T | 1 |
| Grohé, C | 1 |
| Fandrey, J | 1 |
| Meyer, R | 1 |
| Baumgarten, G | 1 |
| Bhat, AS | 1 |
| Krishna, V | 1 |
| Prakash, VR | 1 |
| Bertuglia, S | 1 |
| Arkovitz, MS | 1 |
| Wispé, JR | 1 |
| Garcia, VF | 1 |
| Szabó, C | 2 |
| Meng, X | 1 |
| Ao, L | 1 |
| Brown, JM | 1 |
| Fullerton, DA | 1 |
| Banerjee, A | 1 |
| Harken, AH | 1 |
| Bazzani, C | 1 |
| Bertolini, A | 1 |
| Guarini, S | 1 |
| Wolfárd, A | 1 |
| Kaszaki, J | 1 |
| Balogh, Z | 1 |
| Nagy, S | 1 |
| Rosselet, A | 1 |
| Feihl, F | 1 |
| Markert, M | 1 |
| Gnaegi, A | 1 |
| Perret, C | 1 |
| Liaudet, L | 1 |
| Zhang, J | 1 |
| Cross, AH | 1 |
| McCarthy, TJ | 1 |
| Welch, MJ | 1 |
| Wang, D | 1 |
| Yang, XP | 1 |
| Liu, YH | 1 |
| Carretero, OA | 1 |
| LaPointe, MC | 1 |
| Mitaka, C | 1 |
| Hirata, Y | 1 |
| Masaki, Y | 1 |
| Takei, T | 1 |
| Yokoyama, K | 1 |
| Imai, T | 1 |
| Simsek, I | 1 |
| Mas, MR | 1 |
| Yasar, M | 1 |
| Ozyurt, M | 1 |
| Saglamkaya, U | 1 |
| Deveci, S | 1 |
| Comert, B | 1 |
| Basustaoglu, A | 1 |
| Kocabalkan, F | 1 |
| Refik, M | 1 |
| Takahashi, A | 1 |
| Tomomasa, T | 1 |
| Kaneko, H | 1 |
| Watanabe, T | 1 |
| Tabata, M | 1 |
| Morikawa, H | 1 |
| Tsuchida, Y | 1 |
| Kuwano, H | 1 |
| Cohen, RI | 1 |
| Hassell, AM | 1 |
| Marzouk, K | 1 |
| Marini, C | 1 |
| Liu, SF | 1 |
| Scharf, SM | 1 |
| Jin, D | 1 |
| Liu, X | 1 |
| Hallemeesch, MM | 1 |
| Cobben, DC | 1 |
| Soeters, PB | 1 |
| Deutz, NE | 1 |
| Saito, T | 1 |
| Hu, F | 1 |
| Tayara, L | 1 |
| Fahas, L | 1 |
| Shennib, H | 1 |
| Giaid, A | 1 |
33 other studies available for s-methylisothiopseudouronium and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Effects and Mechanism of Action of Inducible Nitric Oxide Synthase on Apoptosis in a Rat Model of Cerebral Ischemia-Reperfusion Injury.
Topics: Animals; Apoptosis; Behavior, Animal; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; | 2016 |
Inhibition of neuronal and inducible nitric oxide synthase does not affect the analgesic effects of NMDA antagonists in visceral inflammatory pain.
Topics: Acetic Acid; Analgesics; Animals; Calcium Channel Blockers; Disease Models, Animal; Dizocilpine Male | 2016 |
Protective effects of S-methylisothiourea sulfate on different aspiration materials-induced lung injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Enzyme Inhibitors; Infusions, Parenteral; | 2008 |
Scavenging of peroxynitrite reduces renal ischemia/reperfusion injury.
Topics: Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Guanidines; Immunohistochemistry; | 2008 |
Neuroprotective effect of s-methylisothiourea in transient focal cerebral ischemia in rat.
Topics: Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isc | 2010 |
Evaluation of effects of s-methyl isothiourea and melatonin on intestinal ischemia/reperfusion injury in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Glutath | 2010 |
Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats.
Topics: Animals; Antioxidants; Blotting, Western; Disease Models, Animal; Electrophoresis, Polyacrylamide Ge | 2011 |
Regional difference in inflammatory response to LPS-injection in the brain: role of microglia cell density.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Cell Count; Cell Line, Transformed; Cytokin | 2011 |
Protective effects of melatonin and S-methylisothiourea on mechlorethamine induced nephrotoxicity.
Topics: Animals; Chemical Warfare Agents; Disease Models, Animal; Inflammation; Isothiuronium; Kidney Diseas | 2012 |
Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intra-Articular; Iodo | 2013 |
Effect of nitric oxide synthase inhibitor on proteoglycan metabolism in repaired articular cartilage in rabbits.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Cartilage Diseases; Cartilage, Articular; Disease Mod | 2003 |
Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Arginine; Cyclophosphamide; Cystitis; Disease Models, An | 2004 |
[Inhibition of nitric oxide synthesis during bacterial shock does not prevent development of resistant hypotension and death in rats].
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypotension; Isot | 2005 |
COX-2 mediates morphine-induced delayed cardioprotection via an iNOS-dependent mechanism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cardiotonic Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi | 2006 |
Antagonism of lipopolysaccharide-induced blood pressure attenuation and vascular contractility.
Topics: Animals; Aorta; Blood Pressure; Cytokines; Disaccharides; Disease Models, Animal; Dose-Response Rela | 2007 |
The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study.
Topics: Animals; Behavior, Animal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxy | 2008 |
Intermittent hypoxia modulates nitric oxide-dependent vasodilation and capillary perfusion during ischemia-reperfusion-induced damage.
Topics: Acetylcholine; Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Cheek; Cricetinae; Disease | 2008 |
Selective inhibition of the inducible isoform of nitric oxide synthase prevents pulmonary transvascular flux during acute endotoxemia.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Dexamethasone; Disease Models, Animal; Drug Evalua | 1996 |
Nitric oxide synthase is not involved in cardiac contractile dysfunction in a rat model of endotoxemia without shock.
Topics: Animals; Arginine; Blood Pressure; Dexamethasone; Disease Models, Animal; Endotoxemia; Enzyme Inhibi | 1997 |
Inhibition of nitric oxide synthases enhances the effect of ACTH in hemorrhagic shock.
Topics: Animals; Arginine; Cosyntropin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syner | 1997 |
Effects of nitric oxide synthase inhibition on the hemodynamic changes in hyperdynamic endotoxemia.
Topics: Animals; beta-Aminoethyl Isothiourea; Blood Circulation; Blood Pressure; Cardiac Output; Disease Mod | 1997 |
Selective iNOS inhibition is superior to norepinephrine in the treatment of rat endotoxic shock.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluati | 1998 |
Measurement of upregulation of inducible nitric oxide synthase in the experimental autoimmune encephalomyelitis model using a positron emitting radiopharmaceutical.
Topics: Animals; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Isothiuronium; | 1997 |
Reduction of myocardial infarct size by inhibition of inducible nitric oxide synthase.
Topics: Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Cell Death; Cells, Cultured; Disea | 1999 |
S-Methylisothiourea sulfate improves renal, but not hepatic dysfunction in canine endotoxic shock model.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Enzyme Inhibitors; Hemodynamics; Isothiur | 2000 |
Inhibition of inducible nitric oxide synthase reduces bacterial translocation in a rat model of acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Bacterial Translocation; Cecum; Disease Models, Animal; Enterococc | 2001 |
Intestinal motility in an in vivo rat model of intestinal ischemia-reperfusion with special reference to the effects of nitric oxide on the motility changes.
Topics: Animals; Disease Models, Animal; Duodenum; Enzyme Inhibitors; Gastrointestinal Motility; Isothiuroni | 2001 |
Renal effects of nitric oxide in endotoxemia.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Disease Models, | 2001 |
[Long-term effect of nitric oxide synthase inhibitor on repair of articular cartilage defects repairing].
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cartilage, Articular; Disease Models, Animal; Enzyme In | 2002 |
Differential effects of selective and non-selective NOS inhibition on renal arginine and protein metabolism during endotoxemia in rats.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Isothiuronium; Kidney; Ma | 2002 |
Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure.
Topics: Animals; Blotting, Western; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Failu | 2002 |