s-adenosylmethionine has been researched along with Parkinson Disease in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.24) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 9 (31.03) | 29.6817 |
| 2010's | 5 (17.24) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Albillos, SM; Calvo, S; Cubo, E; Montero, O; Solano-Vila, B; Trejo, JM | 1 |
| Chai, JF; Chew, WS; Ching, J; Herr, DR; Khoo, CM; Khor, IW; Kovalik, JP; Raichur, S; Sim, X; Tai, ES; Torta, F; Wenk, MR | 1 |
| Ascherio, A; Bjornevik, K; Clish, C; Healy, B; Hughes, KC; Jeanfavre, S; Molsberry, S; Schwarzschild, M; Zhang, ZJ | 1 |
| Amo, T; Fujimaki, M; Fukuhara, T; Furuya, N; Hatano, T; Hattori, N; Imamichi, Y; Ishikawa, KI; Koinuma, T; Mori, A; Nagumo, M; Nojiri, S; Oji, Y; Okuzumi, A; Saiki, S; Yamashiro, K | 1 |
| Akamatsu, W; Fujimaki, M; Hatano, T; Hattori, N; Ishikawa, KI; Nojiri, S; Oyama, G; Saiki, S; Takeshige-Amano, H; Ueno, SI; Yamaguchi, A | 1 |
| Dillmann, U; Fassbender, K; Herrmann, W; Kostopoulos, P; Obeid, R; Schadt, A | 1 |
| Barone, P; De Bonis, ML; Galletti, P; Ingrosso, D; Longo, K; Pellecchia, MT; Russo, A; Salvatore, A; Tedeschi, G; Tessitore, A; Zappia, V | 1 |
| Müller, T | 1 |
| Allemann, O; Bissantz, C; Burgy, G; Diederich, F; Ehler, A; Ellermann, M; Grünstein, D; Jakob-Roetne, R; Lerner, C; Paulini, R; Rudolph, MG; Stihle, M; Tissot, H | 1 |
| Decker, PA; Dousa, MK; Muenter, MD; Offord, KP; Tyce, GM; Weinshilboum, RM | 1 |
| Di Rocco, A; Werner, P | 2 |
| Diaz-Arrastia, R; O'Suilleabhain, P | 1 |
| Ramsden, DB; Williams, AC | 1 |
| Smythies, JR | 1 |
| Gulliver, PA; Hagan, RM; Raxworthy, MJ | 1 |
| Bottiglieri, T; Hyland, K; Reynolds, EH | 1 |
| Benson, R; Charlton, C; Crowell, B; Doonquah, K; Hill, B | 1 |
| Benson, R; Charlton, CG; Crowell, BG; Shockley, D | 1 |
| Charlton, CG; Crowell, B | 1 |
| Collins, MA; Gearhart, DA; Neafsey, EJ | 1 |
| Aquilonius, SM; Cheng, H; Ekblom, J; Gomes-Trolin, C; Löfberg, C; Oreland, L; Steinberg, A | 1 |
| Charlton, CG | 1 |
| Ballmer, P; Borroni, E; Diederich, F; Jakob-Roetne, R; Masjost, B; Winkler, FK; Zürcher, G | 1 |
| Bottiglieri, T; Brown, R; Di Rocco, A; Rogers, JD; Werner, P | 1 |
| Fowler, B; Hauptmann, B; Kuhn, W; Müller, T; Woitalla, D | 1 |
| Ceccato, S; Passeri, M | 1 |
| Bohuon, C; Comoy, E | 1 |
| Lipinski, J; Matthysse, S; Shih, V | 1 |
3 review(s) available for s-adenosylmethionine and Parkinson Disease
| Article | Year |
|---|---|
Catechol-O-methyltransferase enzyme: cofactor S-adenosyl-L-methionine and related mechanisms.
Topics: Antiparkinson Agents; Catechol O-Methyltransferase; Humans; Levodopa; Parkinson Disease; S-Adenosylmethionine | 2010 |
Autotoxicity, methylation and a road to the prevention of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine Agents; Humans; Methylation; Niacinamide; Parkinson Disease; Parkinson Disease, Secondary; Risk Factors; S-Adenosylmethionine | 2005 |
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.
Topics: AIDS Dementia Complex; Animals; Brain Diseases; Dementia; Disease Models, Animal; Epilepsy; Humans; Metabolism, Inborn Errors; Methotrexate; Methylation; Multiple Sclerosis; Neurotransmitter Agents; Parkinson Disease; Receptors, Neurotransmitter; S-Adenosylmethionine; Spinal Cord Diseases | 1994 |
1 trial(s) available for s-adenosylmethionine and Parkinson Disease
| Article | Year |
|---|---|
S-Adenosyl-Methionine improves depression in patients with Parkinson's disease in an open-label clinical trial.
Topics: Aged; Antidepressive Agents; Depression; Female; Humans; Male; Middle Aged; Parkinson Disease; Patient Dropouts; Pilot Projects; Psychiatric Status Rating Scales; S-Adenosylmethionine; Treatment Outcome | 2000 |
25 other study(ies) available for s-adenosylmethionine and Parkinson Disease
| Article | Year |
|---|---|
Plasma acyl-carnitines, bilirubin, tyramine and tetrahydro-21-deoxycortisol in Parkinson's disease and essential tremor. A case control biomarker study.
Topics: Aged; Bilirubin; Biomarkers; Carnitine; Case-Control Studies; Cognition; Cortodoxone; Diagnosis, Differential; Essential Tremor; Female; Humans; Male; Middle Aged; Parkinson Disease; Tyramine | 2021 |
Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases.
Topics: Alzheimer Disease; Asian People; ATP-Binding Cassette Transporters; Carnitine; China; DNA-Binding Proteins; Female; Galactosyltransferases; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Glutathione Transferase; Glycosphingolipids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Lysophospholipids; Male; Membrane Proteins; Middle Aged; Parkinson Disease; Phosphoric Monoester Hydrolases; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine; Tandem Mass Spectrometry; Transcription Factors | 2020 |
Plasma Metabolomic Markers of Insulin Resistance and Diabetes and Rate of Incident Parkinson's Disease.
Topics: Adult; Aged; Biomarkers; Carnitine; Diabetes Mellitus; Female; Humans; Insulin Resistance; Male; Metabolomics; Middle Aged; Parkinson Disease; Plasma; Risk Factors | 2020 |
Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson's disease.
Topics: Aged; Biomarkers; Carnitine; Cohort Studies; Fatty Acids; Female; Humans; Male; Metabolome; Metabolomics; Middle Aged; Mitochondria; Models, Biological; Muscle, Skeletal; Oxidation-Reduction; Parkinson Disease; ROC Curve; Severity of Illness Index | 2017 |
Zonisamide Administration Improves Fatty Acid β-Oxidation in Parkinson's Disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carnitine; Fatty Acids; Female; Humans; Levodopa; Male; Mental Status and Dementia Tests; Metabolome; Middle Aged; Mitochondria; Oxidation-Reduction; Parkinson Disease; Pilot Projects; Severity of Illness Index; Zonisamide | 2018 |
Methylation status and neurodegenerative markers in Parkinson disease.
Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6 | 2009 |
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.
Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Erythrocytes; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Catechol-O-methyltransferase in complex with substituted 3'-deoxyribose bisubstrate inhibitors.
Topics: Binding Sites; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Crystallography, X-Ray; Deoxyribose; Dopamine; Drug Design; Levodopa; Models, Molecular; Parkinson Disease; Ribose; S-Adenosylmethionine | 2012 |
L-DOPA biotransformation: correlations of dosage, erythrocyte catechol O-methyltransferase and platelet SULT1A3 activities with metabolic pathways in Parkinsonian patients.
Topics: Adenosine Diphosphate; Aged; Arylsulfotransferase; Biotransformation; Blood Platelets; Carbidopa; Catechol O-Methyltransferase; Dose-Response Relationship, Drug; Drug Combinations; Erythrocytes; Female; Humans; Levodopa; Male; Methylation; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Sulfates | 2003 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylation; Parkinson Disease; S-Adenosylmethionine; Vitamin B Complex | 2004 |
Levodopa elevates homocysteine: is this a problem?
Topics: Antiparkinson Agents; Brain; Homocysteine; Humans; Levodopa; Parkinson Disease; Peripheral Nervous System Diseases; S-Adenosylmethionine | 2004 |
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.
Topics: Antiparkinson Agents; Carbon; Catechol O-Methyltransferase Inhibitors; Catechols; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Nitriles; Parkinson Disease; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Time Factors; Vitamin B 12; Vitamin B 6 | 2007 |
The role of the one-carbon cycle in neuropsychiatric disease.
Topics: Bipolar Disorder; Depressive Disorder; Glycine Hydroxymethyltransferase; Humans; Kinetics; Methionine; Methionine Adenosyltransferase; Neurocognitive Disorders; Parkinson Disease; S-Adenosylmethionine; Schizophrenia; Synaptic Transmission; Transferases | 1984 |
Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzyl Compounds; Carbidopa; Catechol O-Methyltransferase; Hydrazines; Kinetics; Liver; Parkinson Disease; S-Adenosylmethionine; Substrate Specificity; Swine | 1980 |
The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance.
Topics: Adenosine Triphosphate; Animals; Brain; Chromatography, High Pressure Liquid; Drug Interactions; Levodopa; Male; Methionine; Methionine Adenosyltransferase; Mice; Parkinson Disease; S-Adenosylmethionine | 1993 |
S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson's disease-like symptoms.
Topics: Animals; Behavior, Animal; Catecholamines; Immobilization; Levodopa; Male; Movement Disorders; Parkinson Disease; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tremor | 1993 |
Striatal dopamine depletion, tremors, and hypokinesia following the intracranial injection of S-adenosylmethionine: a possible role of hypermethylation in parkinsonism.
Topics: Animals; Antiparkinson Agents; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Hypokinesia; Injections, Intraventricular; Levodopa; Male; Methylation; Motor Activity; Neostriatum; Parkinson Disease; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tremor | 1995 |
Characterization of brain beta-carboline-2-N-methyltransferase, an enzyme that may play a role in idiopathic Parkinson's disease.
Topics: Animals; Brain; Carbolines; Cattle; Cytosol; Enzyme Inhibitors; Harmine; Humans; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; Parkinson Disease; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1997 |
Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson's disease.
Topics: Antiparkinson Agents; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Levodopa; Male; Methionine Adenosyltransferase; Middle Aged; Parkinson Disease; S-Adenosylhomocysteine; S-Adenosylmethionine | 1997 |
Depletion of nigrostriatal and forebrain tyrosine hydroxylase by S-adenosylmethionine: a model that may explain the occurrence of depression in Parkinson's disease.
Topics: Animals; Corpus Striatum; Depression; Fluorescent Antibody Technique, Indirect; Male; Parkinson Disease; Prosencephalon; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Substantia Nigra; Tyrosine 3-Monooxygenase | 1997 |
Structure-based design, synthesis, and in vitro evaluation of bisubstrate inhibitors for catechol O-methyltransferase (COMT).
Topics: Animals; Binding Sites; Catechol O-Methyltransferase Inhibitors; Catechols; Drug Design; Enzyme Inhibitors; Kinetics; Liver; Models, Molecular; Parkinson Disease; Rats; S-Adenosylmethionine | 2000 |
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Cardiovascular Diseases; Dopa Decarboxylase; Down-Regulation; Drug Interactions; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Up-Regulation | 2001 |
[Significance of transmethylation and S-adenosylmethionine (SAM) in the management of Parkinson's disease with L-dopa].
Topics: Adenosine; Aged; Brain; Digestive System; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney; Male; Methionine; Methylation; Nausea; Parkinson Disease; S-Adenosylmethionine; Vomiting | 1972 |
[Determination of homoprotocatechic acid in urine by a radioisotopic method].
Topics: Adult; Carbon Isotopes; Catechols; Child; Chromatography, Paper; Dihydroxyphenylalanine; Humans; Methods; Methyltransferases; Neuroblastoma; Parkinson Disease; Phenylacetates; S-Adenosylmethionine | 1972 |
L-dopa and S-adenosylmethionine.
Topics: Adenosine; Carbon Isotopes; Dihydroxyphenylalanine; Humans; Methionine; Parkinson Disease; S-Adenosylmethionine; Time Factors; Tritium | 1971 |