Page last updated: 2024-08-23

s-adenosylmethionine and Neoplasms

s-adenosylmethionine has been researched along with Neoplasms in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (15.94)	18.7374
1990's	4 (5.80)	18.2507
2000's	8 (11.59)	29.6817
2010's	25 (36.23)	24.3611
2020's	21 (30.43)	2.80

Authors

Authors	Studies
Aranda, R; Bobinski, TP; Briere, DM; Burns, AC; Christensen, JG; Clarine, J; Engstrom, LD; Gunn, RJ; Ivetac, A; Jean-Baptiste, R; Ketcham, JM; Kobayashi, M; Kuehler, J; Kulyk, S; Lawson, JD; Marx, MA; Moya, K; Olson, P; Rahbaek, L; Smith, CR; Thomas, NC; Wang, X; Waters, LM	1
Amiano, P; Ardanaz, E; Chajes, V; Gunter, MJ; Huerta, JM; Hultdin, J; Huybrechts, I; Jakszyn, P; Johnson, T; Katzke, V; Keski-Rahkonen, P; Krogh, V; Pokharel, P; Redondo-Sánchez, D; Rothwell, JA; Sacerdote, C; Sandanger, TM; Santucci de Magistris, M; Scalbert, A; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Viallon, V; Wedekind, R; Weiderpass, E; Winkvist, A	1
Liang, Y; Marupaka, R; Mirokhin, Y; Simón-Manso, Y; Stein, SE; Telu, KH; Yan, X	1
Barker, CA; Clasquin, M; Coy, SL; Fornace, AJ; Laiakis, EC; Pfefferkorn, JA; Vera, NB; Vouros, P	1
Fukushima, T; Gomi, D; Kobayashi, T; Koizumi, T; Mamiya, K; Matsushita, H; Sakamoto, A; Sasaki, S; Sekiguchi, N; Tanaka, A	1
Boeing, H; Floegel, A; Johnson, T; Kaaks, R; Kühn, T; Otto, W; Rolle-Kampczyk, U; Sookthai, D; von Bergen, M	1
Evengard, B; Kanakura, Y; Kawata, S; Kitani, T; Kuratsune, H; Långström, B; Lindh, G; Machii, T; Matsumura, K; Takahashi, M; Takaishi, J; Watanabe, Y; Yamaguti, K	1
Han, D; Hoang, V; Kosik, KS; Longhini, AP; Wilson, MZ; Zhang, X	1
Biller, SA; Chen, Y; Frank, V; Gross, S; Hyer, ML; Jin, L; Judd, ET; Konteatis, Z; Lein, M; Li, M; Liu, P; Ma, G; Mandley, E; Marjon, K; Marks, KM; Medeiros, M; Murtie, J; Nagaraja, N; Padyana, AK; Peters, R; Reznik, SK; Sui, Z; Tong, S; Travins, J; Zhou, S	1
Buettner, R; Guo, J; Rosen, ST; Yang, Y	1
Gui, G; Li, C; Qin, A; Zha, X; Zhang, L; Zhou, C	1
Fischer, TR; Helm, M; Hoba, SN; Jung, N; Kersten, C; Koch, J; Lyko, F; Meidner, JL; Schirmeister, T; Schwickert, M; Stark, MM; Weber, M; Windbergs, M; Zimmermann, RA	1
Atkinson, SJ; Evans, L; Scott, JS	1
Chéry, C; Guéant, JL; Namour, F; Oussalah, A; Siblini, Y	1
Fogle, HM; Krupenko, NI; Krupenko, SA; McCormac, JP; Molina, S; Rushing, BR; Sharma, J; Sumner, S; You, M	1
Perez, MF; Sarkies, P	1
Berisa, M; Cross, JR; Qin, W; Schwörer, S; Thompson, CB; Zhu, J	1
Eich, ML; Robinson, AD; Varambally, S	1
Bolotokova, A; Dela Seña, CC; Eram, MS; Li, ASM; Li, F; Vedadi, M	1
Li, MO; Shyu, A; Xu, K	1
Aguado-Fraile, E; Barnett, A; Biller, SA; Chen, CC; Chen, Y; Clasquin, M; Dang, L; Fletcher, M; Frank, V; Goldford, J; Gross, S; Hayes, S; Hyer, ML; Kalev, P; Konteatis, Z; Lein, M; Liu, W; Lizotte, K; Mandley, E; Marjon, K; Marks, KM; Murtie, J; Nagaraja, R; Peters, R; Quang, P; Sellers, K; Simone, E; Sui, Z; Travins, J; Tuncay, Y; Weier, J	1
Fernández, AF; Fraga, MF; Roberti, A	1
Huang, J; Liu, G; Liu, J; Wu, J; Xin, P	1
Barnett, A; Biller, SA; Chen, Y; Dang, L; DeLaBarre, B; Fang, C; Gao, Y; Gross, S; Hyer, ML; Jiang, F; Jin, L; Kalev, P; Konteatis, Z; Liu, Z; Mandley, E; Marjon, K; Marks, KM; Murtie, J; Nagaraja, R; Nicolay, B; Padyana, AK; Sui, Z; Sun, Y; Travins, J; Wei, W; Ye, Z; Yu, J	1
Argyrou, A; Bagal, SK; Börjesson, U; Cheung, T; Chiarparin, E; Collie, I; De Fusco, C; Evans, L; Grondine, M; Lynch, JT; Narasimhan, P; Robb, G; Sanders, MG; Schimpl, M; Scott, JS; Smith, JM; Stubbs, C; Tentarelli, S; Underwood, E; Vazquez-Chantada, M; Wagner, DJ	1
Gao, Y; Martin, NI; van Haren, MJ	1
Bhattacharjee, P; Giri, AK; Paul, S	1
García-Giménez, JL; Pallardó, FV; Peiró-Chova, L; Pérez-Machado, G; Romá-Mateo, C	1
Arsene, D; Lu, SC; Maldonado, LY; Mato, JM	1
Dobrota, D; Hatok, J; Kowtharapu, BS; Murín, R; Vidomanová, E	1
Antonelli-Incalzi, R; Galvano, A; Russo, A; Santini, D; Terenzio, A; Tonini, G; Vespasiani-Gentilucci, U; Vincenzi, B; Vorini, F	1
Fioravanti, R; Mai, A; Stazi, G; Valente, S; Zwergel, C	1
Arimondo, PB; Lascano, S; Lopez, M	1
Coalson, DW; Douglas Wallace, C; Erbe, RW; Hoffman, RM; Stern, PH	1
Hoffman, RM	2
Cao, Y; Gao, M; He, Y; Liu, S; Tang, H; Tao, Y	1
Bröhm, A; Elsawy, H; Jeltsch, A; Kudithipudi, S; Rathert, P; Schoch, T; Schuhmacher, MK; Weirich, S	1
Gorokhov, LV; Karelov, AE; Kremzel', EG; Mitrokhina, MV; Naperov, EV; Nikolaev, AA; Popel', IV; Pyshnaia, IV	1
Blum, GJ; Bothwell, IR; Chen, Y; Deng, H; Dong, A; Islam, K; Luo, M; Min, J; Wu, H; Zeng, H; Zheng, W	1
de la Garza, AL; Haslberger, AG; Lovrecic, L; Martinez, AJ; Migliore, L; Milagro, FI; Peterlin, B; Remely, M	1
Nordgren, KK; Skildum, AJ	1
Chiang, EP; Ko, HA; Lin, YJ; Tang, FY; Wang, YC; Wu, MT	1
Adams, PD; Labuschagne, CF; Maddocks, OD; Vousden, KH	1
Assaraf, YG; Raz, S; Stark, M	1
Cabrera, D; Di Luca, A; Falcon-Perez, JM; Henry, M; Lima, RT; Lopes-Rodrigues, V; Meleady, P; Mleczko, J; O'Connor, R; Pesic, M; van Liempd, S; Vasconcelos, MH	1
Alonso, S; Huang, S; Lu, SC; Perucho, M; Takai, D; Yamamoto, F; Zhou, W	1
Fajardo, I; García-Faroldi, G; Sánchez-Jiménez, F	1
Domann, FE; Hitchler, MJ	1
Erdoğan, A; Gültekin, M; Gümüşlü, S; Sahin, E; Sahin, M	1
Choi, SW; Friso, S; Park, LK	1
Deng, L; Hiou-Tim, F; James, SJ; Li, E; Melnyk, S; Oakes, C; Pogribny, I; Rozen, R; Sibani, S; Trasler, J	1
Murphy, B; O'Reilly, RL; Singh, SM	1
Szyf, M	1
Hancock, RL	1
Hoffman, RM; Stern, PH; Wallace, CD	1
Galletti, P; Seidenfeld, J; Williams-Ashman, HG	1
Bhagwat, AS; Yebra, MJ	1
Jones, PA; Zingg, JM	1
Delongchamp, RR; Poirier, LA; Sinha, R; Wise, CK	1
Deng, L; Hiou-Tim, F; James, SJ; Melnyk, S; Pogribny, IP; Rozen, R; Sibani, S; Trasler, J; Wang, W	1
DiGirolamo, PM; Fujii, K; Huennekens, FM; Jacobsen, DW; Vitols, KS	1
Nau, F	1
Akerman, K; Kajander, O; Karkola, K	1
Haegele, KD; Romijn, JC; Schechter, PJ; Sjoerdsma, A; Splinter, TA	1
van der Westhuyzen, J	1
Russell, DH	1
Bohuon, C; Caillard, L	1
Beaven, MA; Horáková, Z; Jacobsen, S	1

Reviews

32 review(s) available for s-adenosylmethionine and Neoplasms

Article	Year
Targeting the methionine-methionine adenosyl transferase 2A- S -adenosyl methionine axis for cancer therapy. Current opinion in oncology, 2022, 09-01, Volume: 34, Issue:5 Topics: Animals; Carcinogenesis; Humans; Mammals; Methionine; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine	2022
Overview of Methionine Adenosyltransferase 2A (MAT2A) as an Anticancer Target: Structure, Function, and Inhibitors. Journal of medicinal chemistry, 2022, 07-28, Volume: 65, Issue:14 Topics: Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine	2022
A patent review of MAT2a inhibitors (2018-2021). Expert opinion on therapeutic patents, 2022, Volume: 32, Issue:10 Topics: Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; Patents as Topic; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine	2022
Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players. Cells, 2022, 11-15, Volume: 11, Issue:22 Topics: Methionine; Neoplasms; Neoplastic Stem Cells; PPAR alpha; Racemethionine; S-Adenosylmethionine; Sirtuin 1	2022
Dysregulation of de novo nucleotide biosynthetic pathway enzymes in cancer and targeting opportunities. Cancer letters, 2020, 02-01, Volume: 470 Topics: Antimetabolites, Antineoplastic; Biosynthetic Pathways; Cell Proliferation; Energy Metabolism; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Protein Processing, Post-Translational; Purine Nucleotides; Pyrimidine Nucleotides; S-Adenosylmethionine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates	2020
Chemical probes for protein arginine methyltransferases. Methods (San Diego, Calif.), 2020, 03-15, Volume: 175 Topics: Cell Proliferation; Enzyme Assays; Enzyme Inhibitors; F-Box Proteins; Histones; Humans; Kinetics; Neoplasms; Phylogeny; Protein-Arginine N-Methyltransferases; RNA Splicing Factors; S-Adenosylmethionine	2020
Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation. Molecular metabolism, 2021, Volume: 45 Topics: Adipose Tissue; Animals; Epigenesis, Genetic; Humans; Insulin Resistance; Liver; NAD; Neoplasms; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; S-Adenosylmethionine	2021
Biomedical applications of methionine-based systems. Biomaterials science, 2021, Mar-21, Volume: 9, Issue:6 Topics: Cell Proliferation; COVID-19; COVID-19 Drug Treatment; Docetaxel; Humans; Liver Diseases; Methionine; Nanoparticles; Neoplasms; S-Adenosylmethionine; SARS-CoV-2	2021
Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target. Drug discovery today, 2021, Volume: 26, Issue:11 Topics: Enzyme Inhibitors; Humans; Metabolic Diseases; Neoplasms; Neurodegenerative Diseases; Niacinamide; Nicotinamide N-Methyltransferase; S-Adenosylmethionine	2021
Arsenic toxicity and epimutagenecity: the new LINEage. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2017, Volume: 30, Issue:4 Topics: Arsenic; Arsenic Poisoning; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Environmental Exposure; Epigenesis, Genetic; Folic Acid; Genome, Human; Humans; Long Interspersed Nucleotide Elements; Neoplasms; Promoter Regions, Genetic; S-Adenosylmethionine	2017
Role of glutathione in the regulation of epigenetic mechanisms in disease. Free radical biology & medicine, 2017, Volume: 112 Topics: Animals; DNA Methylation; Epigenesis, Genetic; Glutathione; Histones; Humans; Metabolic Syndrome; MicroRNAs; Neoplasms; Neurodegenerative Diseases; Nucleosomes; Protein Processing, Post-Translational; S-Adenosylmethionine	2017
Methionine adenosyltransferases in cancers: Mechanisms of dysregulation and implications for therapy. Experimental biology and medicine (Maywood, N.J.), 2018, Volume: 243, Issue:2 Topics: Animals; Disease Models, Animal; Humans; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine	2018
Role of S-adenosylmethionine cycle in carcinogenesis. General physiology and biophysics, 2017, Volume: 36, Issue:5 Topics: Animals; Carcinogenesis; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Models, Genetic; Neoplasms; S-Adenosylmethionine; Signal Transduction	2017
The use of SAMe in chemotherapy-induced liver injury. Critical reviews in oncology/hematology, 2018, Volume: 130 Topics: Animals; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Neoplasms; S-Adenosylmethionine	2018
Six Years (2012-2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2-Pyridone Compounds. Chemical record (New York, N.Y.), 2018, Volume: 18, Issue:12 Topics: Bridged Bicyclo Compounds; Clinical Trials as Topic; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Indoles; Isoquinolines; Neoplasms; Pyridones; S-Adenosylmethionine	2018
Natural Products and Chemical Biology Tools: Alternatives to Target Epigenetic Mechanisms in Cancers. Chemical record (New York, N.Y.), 2018, Volume: 18, Issue:12 Topics: Biological Products; Catechin; Cell Survival; Depsipeptides; DNA Methylation; Epigenomics; Histone Deacetylase Inhibitors; Humans; Neoplasms; S-Adenosylmethionine	2018
Metabolic Intermediates in Tumorigenesis and Progression. International journal of biological sciences, 2019, Volume: 15, Issue:6 Topics: Acetyl Coenzyme A; Antineoplastic Agents; Carcinogenesis; Cell Proliferation; Disease Progression; Flavin-Adenine Dinucleotide; Humans; NAD; Neoplasm Invasiveness; Neoplasms; S-Adenosylmethionine; Tetrahydrofolates	2019
Therapeutic perspectives of epigenetically active nutrients. British journal of pharmacology, 2015, Volume: 172, Issue:11 Topics: Antineoplastic Agents; Coffee; Curcumin; Diet; Epigenesis, Genetic; Folic Acid; Food; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Metabolic Syndrome; Neoplasms; Neurodegenerative Diseases; Phytoestrogens; Polyphenols; S-Adenosylmethionine; Selenium; Trace Elements; Vitamin B 12; Vitamin B Complex; Vitamins	2015
The deep end of the metabolite pool: influences on epigenetic regulatory mechanisms in cancer. European journal of clinical investigation, 2015, Volume: 45 Suppl 1 Topics: Acetylation; Acetylglucosamine; Citric Acid Cycle; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glycosylation; Histones; Humans; Methylation; Neoplasms; S-Adenosylmethionine; Uridine Diphosphate	2015
Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2016, Volume: 28 Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Methylation; Mice; Neoplasms; Peptide Synthases; Polyglutamic Acid; S-Adenosylmethionine; Signal Transduction	2016
The polyamine and histamine metabolic interplay in cancer and chronic inflammation. Current opinion in clinical nutrition and metabolic care, 2009, Volume: 12, Issue:1 Topics: Chronic Disease; Epigenesis, Genetic; Gastrointestinal Diseases; Histamine; Humans; Inflammation; Mast Cells; Neoplasms; Polyamines; S-Adenosylmethionine	2009
Metabolic defects provide a spark for the epigenetic switch in cancer. Free radical biology & medicine, 2009, Jul-15, Volume: 47, Issue:2 Topics: Acetylation; Animals; DNA Methylation; Epigenesis, Genetic; Free Radicals; Glutathione; Histones; Humans; Neoplasms; Nucleosomes; Oxidation-Reduction; S-Adenosylmethionine	2009
DNA methylation or histone modification status in metastasis and angiogenesis-related genes: a new hypothesis on usage of DNMT inhibitors and S-adenosylmethionine for genome stability. Cancer metastasis reviews, 2010, Volume: 29, Issue:4 Topics: Animals; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Genomic Instability; Histones; Humans; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; S-Adenosylmethionine	2010
Nutritional influences on epigenetics and age-related disease. The Proceedings of the Nutrition Society, 2012, Volume: 71, Issue:1 Topics: Aging; Animals; Cardiovascular Diseases; Diet; DNA Methylation; Epigenesis, Genetic; Epigenomics; Humans; Micronutrients; Neoplasms; Neurodegenerative Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine	2012
Involvement of gene-diet/drug interaction in DNA methylation and its contribution to complex diseases: from cancer to schizophrenia. Clinical genetics, 2003, Volume: 64, Issue:6 Topics: Diet; DNA Methylation; Female; Food-Drug Interactions; Gene Expression Regulation; Humans; Maternal Nutritional Physiological Phenomena; Neoplasms; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Schizophrenia	2003
Therapeutic implications of DNA methylation. Future oncology (London, England), 2005, Volume: 1, Issue:1 Topics: Animals; Chromatin; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Neoplasm Metastasis; Neoplasms; S-Adenosylmethionine	2005
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis. Biochimica et biophysica acta, 1984, Volume: 738, Issue:1-2 Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40	1984
Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine. Biochemical pharmacology, 1982, Feb-01, Volume: 31, Issue:3 Topics: Adenosine; Animals; Deoxyadenosines; Female; Humans; Male; Neoplasms; Purine-Nucleoside Phosphorylase; Rats; Ribosemonophosphates; S-Adenosylmethionine; Spermidine; Spermine; Thioglycosides; Thionucleosides	1982
Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. Carcinogenesis, 1997, Volume: 18, Issue:5 Topics: 5-Methylcytosine; Alleles; Animals; Cell Differentiation; Chromatin; CpG Islands; Cytosine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation; Gene Expression Regulation, Developmental; Humans; Mutation; Neoplasms; S-Adenosylmethionine	1997
B12 -- dependent methionine synthetase as a potential target for cancer chemotherapy. Advances in enzyme regulation, 1976, Volume: 14 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cells, Cultured; Cobamides; Enzyme Activation; Flavoproteins; Leukemia L1210; Methionine; Methyltransferases; Mice; NADP; Neoplasms; S-Adenosylmethionine; Transcobalamins; Vitamin B 12	1976
The methylation of tRNA. Biochimie, 1976, Volume: 58, Issue:6 Topics: Animals; Base Sequence; Binding Sites; Cations, Monovalent; Cell Differentiation; Embryo, Mammalian; Escherichia coli; Gonadal Steroid Hormones; Humans; Methylation; Neoplasms; Nucleic Acid Conformation; Nucleosides; Polyamines; RNA, Transfer; S-Adenosylmethionine; Species Specificity; Structure-Activity Relationship; tRNA Methyltransferases	1976
The roles of the polyamines, putrescine, spermidine, and spermine in normal and malignant tissues. Life sciences, 1973, Dec-16, Volume: 13, Issue:12 Topics: Animals; Carboxy-Lyases; DNA-Directed RNA Polymerases; Drug Synergism; Humans; Neoplasms; Ornithine; Polyamines; Putrescine; RNA; S-Adenosylmethionine; Spermidine; Spermine; Xenopus	1973

Other Studies

37 other study(ies) available for s-adenosylmethionine and Neoplasms

Article	Year
Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Deoxyadenosines; Female; Gene Deletion; Humans; Mice, Nude; Neoplasms; Phthalazines; Protein Binding; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; Thionucleosides; Xenograft Model Antitumor Assays	2022
Determinants of blood acylcarnitine concentrations in healthy individuals of the European Prospective Investigation into Cancer and Nutrition. Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:8 Topics: Carnitine; Diabetes Mellitus, Type 2; Fatty Acids; Humans; Neoplasms; Prospective Studies	2022
Mass Spectrometry Fingerprints of Small-Molecule Metabolites in Biofluids: Building a Spectral Library of Recurrent Spectra for Urine Analysis. Analytical chemistry, 2019, 09-17, Volume: 91, Issue:18 Topics: Body Fluids; Carnitine; Chromatography, Liquid; Humans; Mass Spectrometry; Neoplasms; Small Molecule Libraries; Software	2019
Quantitation of Urinary Acylcarnitines by DMS-MS/MS Uncovers the Effects of Total Body Irradiation in Cancer Patients. Journal of the American Society for Mass Spectrometry, 2020, Mar-04, Volume: 31, Issue:3 Topics: Animals; Biomarkers; Carnitine; Humans; Neoplasms; Pilot Projects; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Whole-Body Irradiation	2020
Dynamics of L-Carnitine in Plasma and Urine in Patients Undergoing Cisplatin Chemotherapy. Chemotherapy, 2017, Volume: 62, Issue:4 Topics: Antineoplastic Agents; Body Mass Index; Carnitine; Cisplatin; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Muscle, Skeletal; Neoplasms	2017
Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a prospective metabolomics study. BMC medicine, 2016, Jan-28, Volume: 14 Topics: Biomarkers, Tumor; Breast Neoplasms; Carnitine; Cohort Studies; Colorectal Neoplasms; Female; Humans; Lipid Metabolism; Lipids; Lysophosphatidylcholines; Male; Middle Aged; Neoplasms; Prospective Studies; Prostatic Neoplasms	2016
Low levels of serum acylcarnitine in chronic fatigue syndrome and chronic hepatitis type C, but not seen in other diseases. International journal of molecular medicine, 1998, Volume: 2, Issue:1 Topics: Acute Disease; Animals; Carnitine; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Fatigue Syndrome, Chronic; Female; Galactosamine; Hepatitis C, Chronic; Humans; Japan; Male; Mice; Mice, Inbred C3H; Neoplasms; Sweden	1998
Dynamic assembly of the mRNA m6A methyltransferase complex is regulated by METTL3 phase separation. PLoS biology, 2022, Volume: 20, Issue:2 Topics: Catalytic Domain; Cell Line, Tumor; Cell Nucleus; Cryptochromes; HEK293 Cells; HeLa Cells; Humans; Luminescent Proteins; Methyltransferases; Microscopy, Confocal; Multiprotein Complexes; Mutation; Neoplasms; Protein Binding; Red Fluorescent Protein; RNA, Messenger; S-Adenosylmethionine	2022
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6 Topics: Brain; Drug Design; Humans; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine	2022
Discovery of Inhibitors of DNA Methyltransferase 2, an Epitranscriptomic Modulator and Potential Target for Cancer Treatment. Journal of medicinal chemistry, 2022, 07-28, Volume: 65, Issue:14 Topics: Archaeal Proteins; Caco-2 Cells; DNA; Humans; Methyltransferases; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine	2022
Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions. Molecules (Basel, Switzerland), 2022, Dec-01, Volume: 27, Issue:23 Topics: Aldehyde Dehydrogenase 1 Family; Folic Acid; Glycine; Humans; Metabolomics; Methylation; Neoplasms; Retinal Dehydrogenase; S-Adenosylmethionine	2022
Histone methyltransferase activity affects metabolism in human cells independently of transcriptional regulation. PLoS biology, 2023, Volume: 21, Issue:10 Topics: Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Neoplasms; Protein Processing, Post-Translational; S-Adenosylmethionine	2023
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Cell metabolism, 2019, 11-05, Volume: 30, Issue:5 Topics: A549 Cells; Animals; Cell Proliferation; Cysteine; Extracellular Space; Female; Gene Knockout Techniques; Hep G2 Cells; Heterografts; Humans; Male; MCF-7 Cells; Methionine; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Protamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tumor Burden	2019
A Tug-of-War Over Methionine. Cell metabolism, 2020, 11-03, Volume: 32, Issue:5 Topics: Histones; Methionine; Methylation; Neoplasms; S-Adenosylmethionine; T-Lymphocytes	2020
MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage. Cancer cell, 2021, 02-08, Volume: 39, Issue:2 Topics: Animals; Cell Line; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; DNA Damage; Enzyme Inhibitors; Gene Deletion; HCT116 Cells; HEK293 Cells; Humans; Methionine Adenosyltransferase; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; RNA Splicing; RNA, Messenger; S-Adenosylmethionine	2021
Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8 Topics: Binding Sites; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Homozygote; Humans; Methionine Adenosyltransferase; Molecular Dynamics Simulation; Neoplasms; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; Structure-Activity Relationship	2021
Fragment-Based Design of a Potent MAT2a Inhibitor and Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10 Topics: Allosteric Site; Animals; Cell Proliferation; Drug Design; Enzyme Inhibitors; Gene Knockout Techniques; Half-Life; HCT116 Cells; Humans; Methionine Adenosyltransferase; Mice; Molecular Dynamics Simulation; Neoplasms; Quinazolines; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Transplantation, Heterologous	2021
Altered Methionine Metabolism in Cancer Cells. Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1866 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine	2019
Is the Hoffman Effect for Methionine Overuse Analogous to the Warburg Effect for Glucose Overuse in Cancer? Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1866 Topics: Aneuploidy; DNA Methylation; G2 Phase; Genomic Instability; Glucose; Glycolysis; Humans; Methionine; Neoplasms; S Phase; S-Adenosylmethionine	2019
Somatic Cancer Mutations in the SUV420H1 Protein Lysine Methyltransferase Modulate Its Catalytic Activity. Journal of molecular biology, 2019, 08-09, Volume: 431, Issue:17 Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; DNA Repair; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neoplasms; Nucleosomes; S-Adenosylmethionine	2019
[The efficacy of hepatotropic agent Remaxol in oncological patients with postoperative liver dysfunction]. Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:7 Topics: Abdominal Cavity; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Female; Humans; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Male; Middle Aged; Neoplasms; Postoperative Period; Recovery of Function; S-Adenosylmethionine; Succinates; Treatment Outcome	2013
Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-15, Volume: 110, Issue:42 Topics: HEK293 Cells; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Signaling Peptides and Proteins; Methylation; Neoplasm Proteins; Neoplasms; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Substrate Specificity	2013
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR). Journal of nutritional science and vitaminology, 2015, Volume: 61 Suppl Topics: Animals; Carbon; DNA Damage; DNA Methylation; Folic Acid; Genotype; Glycine N-Methyltransferase; Hep G2 Cells; Homocysteine; Humans; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Neoplasms; Nucleotides; Nutritional Status; Purines; S-Adenosylmethionine; Uracil	2015
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells. Molecular cell, 2016, Jan-21, Volume: 61, Issue:2 Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Homocysteine; Humans; Methionine; Neoplasms; RNA; S-Adenosylmethionine; Serine; Stress, Physiological	2016
Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles. Scientific reports, 2017, 03-17, Volume: 7 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Extracellular Vesicles; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Methionine; Neoplasms; S-Adenosylmethionine	2017
Requirement of RIZ1 for cancer prevention by methyl-balanced diet. PloS one, 2008, Volume: 3, Issue:10 Topics: Animals; Diet; DNA-Binding Proteins; Food; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Methionine; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Proteins; S-Adenosylmethionine; Transcription Factors	2008
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice. Carcinogenesis, 2003, Volume: 24, Issue:1 Topics: Animals; Cadherins; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Exons; Folic Acid; Folic Acid Deficiency; Mice; Mice, Inbred C57BL; Mutation; Neoplasms; Promoter Regions, Genetic; S-Adenosylmethionine; Tumor Suppressor Protein p53	2003
Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: XII mutational and non-mutational mechanism as subsets of a more general mechanism. Part A--Ethionine. Medical hypotheses, 1984, Volume: 15, Issue:3 Topics: alpha-Fetoproteins; Animals; Carcinogens; DNA, Neoplasm; Embryo, Mammalian; Ethionine; Gene Expression Regulation; Humans; Methylation; Neoplasm Proteins; Neoplasms; S-Adenosylmethionine	1984
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines. Journal of cellular physiology, 1984, Volume: 119, Issue:1 Topics: Cell Line; Homocysteine; Humans; Methionine; Models, Biological; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine	1984
A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine. Biochemistry, 1995, Nov-14, Volume: 34, Issue:45 Topics: 5-Methylcytosine; Cytosine; DNA; DNA-Cytosine Methylases; Escherichia coli; Humans; Methylation; Molecular Structure; Mutagenesis; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymine	1995
Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:6 Topics: Body Mass Index; Diet; Dietary Fats; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Neoplasms; Pyridoxine; Reference Values; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine	2001
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice. Carcinogenesis, 2002, Volume: 23, Issue:1 Topics: Animals; Biomarkers; Choline Deficiency; Diet; DNA Methylation; Folic Acid Deficiency; Intestinal Neoplasms; Methionine; Mice; Neoplasms; Precancerous Conditions; S-Adenosylhomocysteine; S-Adenosylmethionine	2002
Methionine adenosyltransferase activity in cultured cells and in human tissues. Biochimica et biophysica acta, 1991, Sep-23, Volume: 1097, Issue:2 Topics: Animals; Brain; Cell Division; Cell Extracts; Cell Line; Cells, Cultured; Colon; Cricetinae; Humans; Kinetics; Male; Methionine Adenosyltransferase; Mice; Neoplasms; Prostate; Rats; S-Adenosylmethionine; Tissue Extracts; Tumor Cells, Cultured	1991
Decarboxylated-S-adenosylmethionine excretion: a biochemical marker of ornithine decarboxylase inhibition by alpha-difluoromethylornithine. Cancer research, 1987, Feb-01, Volume: 47, Issue:3 Topics: Aged; Creatinine; Eflornithine; Female; Humans; Kinetics; Male; Middle Aged; Neoplasms; Ornithine Decarboxylase Inhibitors; Polyamines; S-Adenosylmethionine	1987
Methionine metabolism and cancer. Nutrition and cancer, 1985, Volume: 7, Issue:3 Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Gene Expression Regulation; Mammals; Methionine; Methylation; Methyltransferases; Models, Biological; Neoplasms; S-Adenosylmethionine	1985
S-adenosylmethionine in human blood. Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 33, Issue:1 Topics: Adenosine; Adult; Child; Child, Preschool; Humans; Leukemia; Methionine; Methyltransferases; Neoplasms; Neuroblastoma; Radioisotope Dilution Technique; S-Adenosylmethionine	1971
Modification of the enzymatic isotopic assay of histamine and its application to measurement of histamine in tissues, serum and urine. Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 37 Topics: Ammonium Sulfate; Animals; Brain; Carbon Isotopes; Chemical Precipitation; Female; Guinea Pigs; Histamine; Humans; Kinetics; Male; Methods; Methyltransferases; Microchemistry; Neoplasms; Rats; S-Adenosylmethionine; Spectrometry, Fluorescence; Tritium	1972