s-adenosylmethionine has been researched along with Liver Dysfunction in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (21.79) | 18.7374 |
| 1990's | 17 (21.79) | 18.2507 |
| 2000's | 23 (29.49) | 29.6817 |
| 2010's | 17 (21.79) | 24.3611 |
| 2020's | 4 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| He, R; Huang, M; Kang, L; Li, X; Li, Y; Liu, Y; Ma, R; Men, J; Ren, J; Song, J; Yang, Y | 1 |
| Chen, C; Gonzalez, FJ; Idle, JR; Krausz, KW; Shah, YM | 1 |
| Al-Dirbashi, OY; Chakraborty, P; Fisher, L; Geraghty, M; McRoberts, C; Siriwardena, K | 1 |
| Eskelin, PM; Laitinen, KA; Tyni, TA | 1 |
| Chen, S; Lin, X; Lu, X; Wang, Q; Wu, Z; Xing, W; Xu, G; Yin, P; Zhang, Y; Zhou, L | 1 |
| Bennett, MJ; Fuda, F; Narayan, SB; Squires, RH | 1 |
| Rosas-Rodríguez, JA; Valenzuela-Soto, EM | 1 |
| Aspichueta, P; Azkargorta, M; Banales, JM; Bujanda, L; Caballero-Camino, FJ; Drenth, JPH; Elortza, F; Izquierdo-Sanchez, L; LaRusso, NF; Lee-Law, PY; Martinez-Chantar, ML; Marzioni, M; Olaizola, P; Perugorria, MJ; Rodrigues, PM; Santos-Laso, A | 1 |
| Huang, J; Liu, G; Liu, J; Wu, J; Xin, P | 1 |
| Brzački, V; Dimić, D; Djukić, D; Jeremić, L; Mladenović, B; Sokolović, DT; Stojanović, NM; Živanović, D | 1 |
| Kondrashina, EA; Raikhelson, KL | 1 |
| Ravishankar, AC; Singh, T; Virukalpattigopalratnam, MP | 1 |
| Iartseva, DV; Tumanian, SV | 1 |
| Bing, Y; Guo, T; He, Y; Li, C; Li, T; Liu, Q; Liu, W; Liu, Z; Qi, H; Xiao, Y; Yu, G; Yuan, Y | 1 |
| Chang, L; Guo, T; Liu, Q; Xiao, Y | 1 |
| Anilkumar, N; Brandes, RP; Brewer, AC; Burr, S; Caldwell, A; Dew, T; Dong, X; Halket, J; Hughes, RD; Martin, D; Mistry, RK; Murray, TV; Quaglia, A; Sawyer, GJ; Schröder, K; Shah, AM; Sherwood, R | 1 |
| Ballhausen, D; Blom, HJ; Dionisi-Vici, C; Dobbelaere, D; Douillard, C; Freisinger, P; Grünert, SC; Haas, D; Hoffmann, GF; Kahrizi, K; Kölker, S; la Marca, G; Lindner, M; Makhseed, N; Staufner, C; Straub, BK | 1 |
| Feng, D; French, SW; Ganesan, M; Kharbanda, KK; Maillacheruvu, PF; Orlicky, DJ; Osna, NA; Tuma, DJ | 1 |
| Ariz, U; Embade, N; Fernandez-Ramos, D; Gomez-Santos, L; Lu, SC; Martinez-Chantar, ML; Martínez-López, N; Mato, JM; Varela-Rey, M; Vazquez-Chantada, M | 1 |
| Cooper, J; Webster, CR | 1 |
| Golovanova, EV; Noskova, KK; Petrakov, AV | 1 |
| Balasubramaniam, S; Bjursell, MK; Blom, HJ; Brandberg, G; Cayuela, JA; Engvall, ML; Falkenberg, M; Gustafsson, CM; Halldin, M; Jakobs, C; Lesko, N; Lundeberg, J; Smith, D; Struys, E; von Döbeln, U; Wedell, A | 1 |
| Anstee, QM; Day, CP | 1 |
| Lu, SC; Mato, JM | 2 |
| Cederbaum, AI | 1 |
| Minushkin, ON | 1 |
| Bottiglieri, T | 1 |
| Lieber, CS | 2 |
| Toporkov, AS; Vostrikov, GP | 1 |
| Finkelstein, JD | 1 |
| Chiappelli, F; Coulter, I; Favreau, J; Hardy, ML; Jungvig, LK; Morton, SC; Orshansky, G; Rossi, F; Roth, EA; Shekelle, P; Suttorp, MJ; Venuturupalli, S | 1 |
| McMillan, DC; McMillan, JM | 1 |
| Avila, MA; Berasain, C; Corrales, FJ; Fernandez-Irigoyen, J; Lu, SC; Mato, JM; Mora, MI; Muñoz, J; Prieto, J; Santamaría, E; Sesma, L | 1 |
| Brosnan, JT; Brosnan, ME; da Silva, R | 1 |
| Caro, AA; Cederbaum, AI; Dey, A | 1 |
| Muriel, P; Rivera-Espinoza, Y | 1 |
| Shan, RB; Zhu, MZ | 1 |
| Cederbaum, AI; Wang, X | 1 |
| Alvarez Chiva, V; Mato, JM | 1 |
| Ravetta, A | 1 |
| Giannelli, G; Rina, D; Silvi, G | 1 |
| Carbone, G; Cerotto, GM; Corbosiero, L; De Caprio, M; Vitale, A | 1 |
| Almasio, P; Pagliaro, L | 1 |
| Burroughs, AK; Osman, E; Owen, JS | 1 |
| Mato, JM; Ortiz, P | 1 |
| Ermolin, SN; Gorbakov, VV; Kalinin, AV | 1 |
| Alvarez, L; Mato, JM; Ortiz, P; Pajares, MA | 1 |
| Bontemps, F; Van Den Berghe, G | 1 |
| Nurmukhametova, EA; Reĭzis, AR | 1 |
| Cowley, G; Underwood, A | 1 |
| Chavez, M | 1 |
| Boorstin, J | 1 |
| Avila, MA; Corrales, FJ; Lu, SC; Mato, JM | 1 |
| Il'chenko, LIu; Vinnitskaia, EV | 1 |
| Avila, MA; Chen, L; Corrales, FJ; García-Trevijano, ER; Huang, ZZ; Kanel, G; Lu, SC; Martínez-Chantar, ML; Martínez-Cruz, LA; Mato, JM | 1 |
| Angioli, D; Arcangeli, A; Auteri, A; Boggiano, CA; Boncompagni, P; Camarri, E; Candidi Tommasi, A; Caremani, M; Di Perri, T; Forconi, A; Lomi, M; Magnolfi, F; Mazzanti, R; Motta, R; Pippi, L; Salvadori, G; Smorlesi, C; Soldi, A; Toti, M | 1 |
| Frezza, M; Gilotta, S; Milani, S; Nicolini, R; Pozzato, G; Valente, G | 1 |
| Ideo, G | 1 |
| Cantoni, L; Maggi, G; Mononi, G; Preti, G | 1 |
| Gasbarrini, GB; Labò, G | 1 |
| Burroughs, AK; Guardascione, M; Osman, E; Owen, JS; Rafique, S | 1 |
| Lieber, CS; Williams, R | 1 |
| Blake, JC; Burroughs, AK; Kaye, GL | 1 |
| Cabrero, C; Corrales, F; Martin-Duce, A; Mato, JM; Ortiz, P; Pajares, MA | 1 |
| Owen, JS | 1 |
| Bonkovsky, HL; Chawla, RK; Galambos, JT | 1 |
| Bortolini, M; Di Padova, C; Fiaccadori, F; Frezza, M; Manzillo, G; Surrenti, C | 1 |
| Budillon, G; Cantoni, L; Cuomo, R; Di Padova, C; Le Grazie, C; Rizzardini, M; Rodinò, S | 1 |
| Benfield, P; Friedel, HA; Goa, KL | 1 |
| Albano, O; Altomare, E; Carrieri, V; Di Padova, C; Le Grazie, C; Salerno, MT; Trizio, T; Vendemiale, G | 1 |
| Fischer, JE; James, JH | 1 |
| Durigato, S | 1 |
| Ceccato, S; Passeri, M | 1 |
| Dallari, A; Jori, E | 1 |
| Gasbarrini, G; Labò, G; Miglio, F | 1 |
| Cavalieri, U; Leonelli, G | 1 |
28 review(s) available for s-adenosylmethionine and Liver Dysfunction
| Article | Year |
|---|---|
The glycine betaine role in neurodegenerative, cardiovascular, hepatic, and renal diseases: Insights into disease and dysfunction networks.
Topics: Betaine; Cardiovascular Diseases; Cell Size; Humans; Hyperhomocysteinemia; Kidney Diseases; Liver Diseases; Neurodegenerative Diseases; Osmolar Concentration; S-Adenosylmethionine | 2021 |
Biomedical applications of methionine-based systems.
Topics: Cell Proliferation; COVID-19; COVID-19 Drug Treatment; Docetaxel; Humans; Liver Diseases; Methionine; Nanoparticles; Neoplasms; S-Adenosylmethionine; SARS-CoV-2 | 2021 |
Аdеmethionine in the treatment of fatigue in liver diseases: a systematic review.
Topics: Fatigue; Humans; Liver Diseases; S-Adenosylmethionine; Treatment Outcome | 2019 |
S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis.
Topics: Age Factors; Chronic Disease; Humans; Liver Diseases; Liver Function Tests; S-Adenosylmethionine; Treatment Outcome | 2015 |
Therapeutic use of cytoprotective agents in canine and feline hepatobiliary disease.
Topics: Acetylcysteine; Animals; Antioxidants; Biliary Tract Diseases; Cat Diseases; Cats; Cholagogues and Choleretics; Cryoprotective Agents; Dog Diseases; Dogs; Free Radical Scavengers; Liver Diseases; S-Adenosylmethionine; Silymarin; Ursodeoxycholic Acid; Vitamin E | 2009 |
S-adenosylmethionine (SAMe) therapy in liver disease: a review of current evidence and clinical utility.
Topics: Chronic Disease; Evidence-Based Medicine; Humans; Liver Diseases; S-Adenosylmethionine; Severity of Illness Index | 2012 |
S-adenosylmethionine in liver health, injury, and cancer.
Topics: Animals; Humans; Liver; Liver Diseases; Liver Neoplasms; Methionine Adenosyltransferase; S-Adenosylmethionine | 2012 |
CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment.
Topics: Animals; Cytochrome P-450 CYP2E1; Disease Models, Animal; Ethanol; Humans; Liver Diseases; Liver Diseases, Alcoholic; Mice; Mice, Knockout; Obesity; Oxidative Stress; S-Adenosylmethionine | 2012 |
S-Adenosyl-L-methionine (SAMe): from the bench to the bedside--molecular basis of a pleiotrophic molecule.
Topics: Animals; Depression; Diffusion of Innovation; Humans; Liver Diseases; Methylation; Nervous System Diseases; Osteoarthritis; S-Adenosylmethionine; Tissue Distribution | 2002 |
S-adenosyl-L-methionine: its role in the treatment of liver disorders.
Topics: Animals; Antioxidants; Humans; Liver Diseases; Liver Diseases, Alcoholic; Reactive Oxygen Species; S-Adenosylmethionine | 2002 |
[Use of heptral in chronic liver diseases].
Topics: Chronic Disease; Humans; Liver Diseases; S-Adenosylmethionine | 2002 |
S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease.
Topics: Cholestasis, Intrahepatic; Depressive Disorder; Female; Humans; Liver Diseases; Osteoarthritis; Pregnancy; Pregnancy Complications; S-Adenosylmethionine | 2003 |
Amino acids and the regulation of methyl balance in humans.
Topics: Amino Acids; Animals; Creatine; Epigenesis, Genetic; Humans; Liver Diseases; Methionine; Methylation; Mice; Mutation; Neural Tube Defects; Polymorphism, Genetic; S-Adenosylmethionine | 2007 |
Role of S-adenosyl-L-methionine in liver health and injury.
Topics: Animals; Apoptosis; Hepatocytes; Humans; Liver; Liver Diseases; Methionine Adenosyltransferase; S-Adenosylmethionine | 2007 |
Beneficial drugs for liver diseases.
Topics: Adrenal Cortex Hormones; Animals; Colchicine; Curcumin; Disease Models, Animal; Drug Combinations; Glycyrrhizic Acid; Humans; Interferons; Liver Diseases; Nitric Oxide; Plant Extracts; Resveratrol; S-Adenosylmethionine; Silymarin; Stilbenes; Thalidomide | 2008 |
[Pathogenesis and progress in treatment of neonatal total parenteral nutrition-associated cholestasis].
Topics: Cholestasis; Female; Humans; Liver Diseases; Male; Neonatology; Parenteral Nutrition, Total; S-Adenosylmethionine; Ursodeoxycholic Acid | 2008 |
[Ademetionine: the state of the art and future prospects].
Topics: Chronic Disease; Humans; Liver Diseases; S-Adenosylmethionine | 1993 |
Review article: S-adenosyl-L-methionine--a new therapeutic agent in liver disease?
Topics: Animals; Female; Humans; Liver Diseases; Pregnancy; S-Adenosylmethionine | 1993 |
Metabolism of methionine in liver disease.
Topics: Clinical Trials as Topic; Humans; Liver; Liver Diseases; Methionine; S-Adenosylmethionine | 1996 |
S-adenosylmethionine synthesis: molecular mechanisms and clinical implications.
Topics: Animals; Chemical and Drug Induced Liver Injury; Gene Expression Regulation, Enzymologic; Humans; Liver; Liver Diseases; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Species Specificity | 1997 |
SAMe: S-Adenosylmethionine.
Topics: Arthritis; Depression; Humans; Liver Diseases; S-Adenosylmethionine | 2000 |
S-Adenosylmethionine: a control switch that regulates liver function.
Topics: Animals; Cell Differentiation; Cell Division; Disease Models, Animal; Humans; Liver; Liver Diseases; Methionine Adenosyltransferase; Mice; Models, Biological; Protein Processing, Post-Translational; S-Adenosylmethionine | 2002 |
[Metabolism pathways and use of heptral in chronic liver diseases].
Topics: Chemical and Drug Induced Liver Injury; Chronic Disease; Clinical Trials as Topic; Hepatitis, Viral, Human; Humans; Liver; Liver Diseases; S-Adenosylmethionine | 2002 |
Metabolism of exogenous S-adenosyl-L-methionine in patients with liver disease.
Topics: Animals; Humans; Liver Diseases; S-Adenosylmethionine | 1990 |
Mechanisms and consequences of the impaired trans-sulphuration pathway in liver disease: Part I. Biochemical implications.
Topics: Humans; Liver; Liver Diseases; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 1990 |
Extrahepatic cell membrane lipid abnormalities and cellular dysfunction in liver disease.
Topics: Humans; Lipoproteins; Liver Diseases; Membrane Lipids; S-Adenosylmethionine | 1990 |
Biochemistry and pharmacology of S-adenosyl-L-methionine and rationale for its use in liver disease.
Topics: Animals; Cell Membrane; Depressive Disorder; Humans; Liver Diseases; Methylation; S-Adenosylmethionine | 1990 |
S-adenosyl-L-methionine. A review of its pharmacological properties and therapeutic potential in liver dysfunction and affective disorders in relation to its physiological role in cell metabolism.
Topics: Animals; Clinical Trials as Topic; Double-Blind Method; Humans; Liver Diseases; Mood Disorders; S-Adenosylmethionine | 1989 |
8 trial(s) available for s-adenosylmethionine and Liver Dysfunction
| Article | Year |
|---|---|
[A trial of using Geptral in patients with chronic liver diseases].
Topics: Adolescent; Adult; Aged; Cholestasis, Intrahepatic; Chronic Disease; Humans; Liver Diseases; Male; Middle Aged; S-Adenosylmethionine; Time Factors | 1996 |
[S-Adenosylmethionine: plasma levels in hepatic cirrhosis and preliminary results of its clinical use in hepatology. Double-blind study].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Hepatitis; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Middle Aged; S-Adenosylmethionine | 1975 |
[Relations between protidopoiesis and biological transmethylations: action of S-adenosylmethionine on protein crasis in chronic hepatopathies].
Topics: Blood Proteins; Chronic Disease; Clinical Trials as Topic; Hepatitis; Humans; Liver; Liver Cirrhosis; Liver Diseases; Methyltransferases; Protein Biosynthesis; RNA; S-Adenosylmethionine; Serum Albumin | 1975 |
Reversal of extrahepatic membrane cholesterol deposition in patients with chronic liver diseases by S-adenosyl-L-methionine.
Topics: Acetylcholinesterase; Adult; Cholesterol; Chronic Disease; Erythrocyte Membrane; Female; Humans; Liver Diseases; Male; Phospholipids; S-Adenosylmethionine; Time Factors | 1992 |
Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study.
Topics: Administration, Oral; Aged; Cholestasis, Intrahepatic; Chronic Disease; Double-Blind Method; Female; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Randomized Controlled Trials as Topic; S-Adenosylmethionine | 1990 |
S-adenosyl-L-methionine. A review of its pharmacological properties and therapeutic potential in liver dysfunction and affective disorders in relation to its physiological role in cell metabolism.
Topics: Animals; Clinical Trials as Topic; Double-Blind Method; Humans; Liver Diseases; Mood Disorders; S-Adenosylmethionine | 1989 |
Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease.
Topics: Adult; Female; Glutathione; Humans; Liver; Liver Diseases; Liver Diseases, Alcoholic; Male; Middle Aged; S-Adenosylmethionine; Tablets | 1989 |
[S-adenosylmethionine in the therapy of liver insufficiency during a course of pulmonary tuberculosis].
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; S-Adenosylmethionine; Tuberculosis, Pulmonary | 1972 |
43 other study(ies) available for s-adenosylmethionine and Liver Dysfunction
| Article | Year |
|---|---|
One potential hotspot ACADVL mutation in Chinese patients with very-long-chain acyl-coenzyme A dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Asian People; Carnitine; China; Congenital Bone Marrow Failure Syndromes; Female; Humans; Hypoglycemia; Infant, Newborn; Lipid Metabolism, Inborn Errors; Liver Diseases; Male; Mitochondrial Diseases; Muscular Diseases; Mutation | 2020 |
Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Animals; Carnitine; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytochrome P-450 CYP2E1; Fatty Acids; Glutathione; Liver Diseases; Mass Spectrometry; Metabolomics; Mice; Mice, Knockout; PPAR alpha; Time Factors | 2009 |
Identification of a neonate with hepatorenal tyrosinemia by combined routine newborn screening for succinylacetone, acylcarnitines and amino acids.
Topics: Amino Acids; Carnitine; Heptanoates; Humans; Infant, Newborn; Kidney Diseases; Liver Diseases; Neonatal Screening; Tandem Mass Spectrometry; Tyrosinemias | 2010 |
Elevated hydroxyacylcarnitines in a carrier of LCHAD deficiency during acute liver disease of pregnancy - a common feature of the pregnancy complication?
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acute Disease; Adult; Carnitine; Fatty Liver; Female; Humans; Lipid Metabolism, Inborn Errors; Liver Diseases; Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase; Mitochondrial Trifunctional Protein; Multienzyme Complexes; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third | 2010 |
Serum metabolomics reveals the deregulation of fatty acids metabolism in hepatocellular carcinoma and chronic liver diseases.
Topics: Carcinoma, Hepatocellular; Carnitine; Chromatography, Liquid; Chronic Disease; Fatty Acids; Humans; Liver Diseases; Liver Neoplasms; Mass Spectrometry; Metabolomics | 2012 |
Bile acylcarnitine profiles in pediatric liver disease do not interfere with the diagnosis of long-chain fatty acid oxidation defects.
Topics: Bile; Biopsy; Carnitine; Fatty Acids; Humans; Infant; Liver Diseases; Oxidation-Reduction | 2006 |
Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models.
Topics: Animals; Apoptosis; Bile Ducts; Cell Proliferation; Cysts; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Liver Diseases; Models, Theoretical; Proteasome Endopeptidase Complex; Rats; RNA, Small Interfering; S-Adenosylmethionine; Sumoylation; Ubiquitin-Conjugating Enzymes | 2021 |
Comparison between the effects of selenomethionine and S-adenosylmethionine in preventing cholestasis-induced rat liver damage.
Topics: Animals; Catalase; Cholestasis; Liver Diseases; Male; Rats; Rats, Wistar; S-Adenosylmethionine; Selenomethionine; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 2019 |
Heptral (ademetionine) in patients with intrahepatic cholestasis in chronic liver disease due to non-alcoholic liver disease: results of a multicentre observational study in India.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Cholestasis, Intrahepatic; Female; gamma-Glutamyltransferase; Humans; India; Liver Diseases; Male; S-Adenosylmethionine | 2013 |
[Effect of hepatic functional activity of the liver and endogenous intoxication in patients with ovarian cancer].
Topics: Adult; Aged; Comparative Effectiveness Research; Drug Monitoring; Female; Humans; Liver Diseases; Liver Function Tests; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Ovariectomy; Perioperative Period; Prognosis; Protective Agents; Russia; S-Adenosylmethionine; Severity of Illness Index; Succinates | 2014 |
The plasma S-adenosylmethionine level is associated with the severity of hepatitis B-related liver disease.
Topics: Case-Control Studies; Female; Hepatitis B, Chronic; Humans; Liver Diseases; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Prothrombin Time; ROC Curve; S-Adenosylmethionine; Sensitivity and Specificity; Serum Albumin; Severity of Illness Index | 2015 |
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine | 2015 |
Adenosine kinase deficiency: expanding the clinical spectrum and evaluating therapeutic options.
Topics: Adenosine; Adenosine Kinase; Adolescent; Adult; Biomarkers; Child; Child, Preschool; Diet; Female; Humans; Hypoglycemia; Infant; Liver; Liver Diseases; Male; Metabolic Diseases; Methionine; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Young Adult | 2016 |
Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury.
Topics: Alanine Transaminase; Amidinotransferases; Animals; Aspartate Aminotransferases; Body Weight; Calcium-Binding Proteins; Cholesterol; Dietary Supplements; DNA-Binding Proteins; Ethanol; Fatty Acids; Fatty Liver; Glycine; Guanidinoacetate N-Methyltransferase; Homocysteine; Inflammation; Insulin; Liver; Liver Diseases; Male; Nerve Tissue Proteins; Nucleobindins; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2016 |
S-adenosylmethionine and proliferation: new pathways, new targets.
Topics: AMP-Activated Protein Kinases; Animals; Antigens, Surface; Cell Proliferation; Disease Models, Animal; ELAV Proteins; ELAV-Like Protein 1; Hepatocytes; Humans; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; Multienzyme Complexes; Protein Serine-Threonine Kinases; RNA-Binding Proteins; S-Adenosylmethionine; Signal Transduction | 2008 |
[Intrahepatic cholestasis in chronic liver diseases].
Topics: Blood Coagulation; Cholestasis, Intrahepatic; Chronic Disease; Drug Therapy, Combination; Humans; Liver Diseases; Liver Function Tests; Prognosis; Quality of Life; S-Adenosylmethionine; Severity of Illness Index; Treatment Outcome; Ursodeoxycholic Acid | 2011 |
Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.
Topics: Adenosine Kinase; Adult; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Child; Developmental Disabilities; Family Health; Female; Fibroblasts; Homocysteine; Humans; Liver Diseases; Male; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
[Heptral in treating chronic liver diseases].
Topics: Chronic Disease; Humans; Liver Diseases; S-Adenosylmethionine | 2002 |
Methionine metabolism in liver diseases.
Topics: Humans; Hyperhomocysteinemia; Liver; Liver Diseases; Methionine; S-Adenosylmethionine | 2003 |
S-adenosylmethionine but not glutathione protects against galactosamine-induced cytotoxicity in rat hepatocyte cultures.
Topics: Animals; Cells, Cultured; Galactosamine; Glutathione; Hepatocytes; L-Lactate Dehydrogenase; Liver Diseases; Male; Maleates; Rats; Rats, Long-Evans; S-Adenosylmethionine | 2006 |
Molecular profiling of hepatocellular carcinoma in mice with a chronic deficiency of hepatic s-adenosylmethionine: relevance in human liver diseases.
Topics: Adult; Aged; Aged, 80 and over; Animals; Carcinoma, Hepatocellular; Case-Control Studies; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Liver Diseases; Liver Neoplasms; Mass Spectrometry; Mice; Mice, Knockout; Middle Aged; Peptide Mapping; Protein Array Analysis; Proteome; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Tumor Burden; Up-Regulation | 2006 |
S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; DNA Fragmentation; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria, Liver; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrazoles; S-Adenosylmethionine | 2007 |
S-adenosyl-L-methionine decreases the elevated hepatotoxicity induced by Fas agonistic antibody plus acute ethanol pretreatment in mice.
Topics: Animals; Antibodies; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Ethanol; fas Receptor; Immunohistochemistry; In Situ Nick-End Labeling; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Mitochondrial Swelling; Nitric Oxide Synthase Type II; Oxidative Stress; S-Adenosylmethionine; Tumor Necrosis Factor-alpha | 2008 |
[Clinical use of S-adenosylmethionine].
Topics: Animals; Humans; Liver Diseases; Mental Disorders; Rats; S-Adenosylmethionine | 1983 |
[Ambulatory treatment of hepatic damage: comparison of 2 therapeutic modalities].
Topics: Coenzyme A; Drug Therapy, Combination; Flavonoids; Humans; Liver Diseases; Liver Extracts; S-Adenosylmethionine; Silymarin; Vitamin B Complex; Vitamin E; Vitamin K | 1981 |
[Effectiveness of S-adenosylmethionine (SAM) in the treatment of chronic liver diseases].
Topics: Adult; Aged; Chronic Disease; Female; Humans; Liver Diseases; Male; Middle Aged; S-Adenosylmethionine | 1980 |
[Behaviour of ammonemia during treatment of chronic/hyperammonemic hepatopathy with S-adenosyl-L-methionine].
Topics: Adult; Aged; Ammonia; Chronic Disease; Female; Hepatic Encephalopathy; Humans; Liver Diseases; Male; Middle Aged; S-Adenosylmethionine | 1980 |
Metabolism of exogenous S-adenosylmethionine in isolated rat hepatocyte suspensions: methylation of plasma-membrane phospholipids without intracellular uptake.
Topics: Adenosine; Animals; Cells, Cultured; Humans; Kinetics; Liver; Liver Diseases; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1997 |
[Heptral potentialities in the treatment of hepatic damage in children with malignant blood disease].
Topics: Adolescent; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Biomarkers; Child; Child, Preschool; Drug Administration Routes; Follow-Up Studies; Hematologic Neoplasms; Humans; Liver Diseases; Male; Retrospective Studies; S-Adenosylmethionine | 1998 |
Role of S-adenosyl-L-methionine in the treatment of liver diseases.
Topics: Animals; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Methionine; Middle Aged; Rats; S-Adenosylmethionine | 1999 |
What is SAMe? S-Adenosylmethionine.
Topics: Arthritis; Chronic Disease; Depression; Dietary Supplements; Health Education; Humans; Liver Diseases; Methylation; Nonprescription Drugs; S-Adenosylmethionine; United States | 1999 |
Users say SAM-e is a wonder drug ... are they high?
Topics: Depression; Humans; Liver Diseases; Osteoarthritis; S-Adenosylmethionine; United States | 2000 |
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Diabetes Mellitus; Disease Susceptibility; Gene Expression Profiling; Hepatitis, Animal; Ion Channels; Liver; Liver Diseases; Liver Neoplasms, Experimental; Membrane Transport Proteins; Methionine Adenosyltransferase; Mice; Mice, Knockout; Mitochondrial Proteins; Models, Biological; Obesity; Oxidative Stress; Protein Biosynthesis; Proteins; RNA, Messenger; S-Adenosylmethionine; Uncoupling Protein 2 | 2002 |
[The anti-steatosic effect of sulfo-adenosylmethionine (SAMe) in various forms of chronic hepatopathy. Multicentric research].
Topics: Adult; Aged; Chronic Disease; Drug Evaluation; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Middle Aged; S-Adenosylmethionine | 1978 |
[S-adenosylmethionine as a regulator of protein synthesis. Influence on plasmatic fibrinogen].
Topics: Adult; Aged; Blood Sedimentation; Blood Viscosity; Chronic Disease; Female; Fibrinogen; Humans; Liver Diseases; Male; Middle Aged; S-Adenosylmethionine; Thrombelastography | 1977 |
[Therapeutic action of S-adenosylmethionine in some chronic hepatopathies].
Topics: Adult; Aged; Chronic Disease; Fatty Liver; Female; Hepatitis; Humans; Jaundice; Liver Diseases; Male; Middle Aged; S-Adenosylmethionine | 1975 |
The role of SAMe in the treatment of liver disease.
Topics: Humans; Liver Diseases; S-Adenosylmethionine | 1990 |
Protective effect of S-adenosyl-L-methionine in hepatic uroporphyria. Evaluation in an experimental model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Hexachlorobenzene; Liver Diseases; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Skin Diseases; Uroporphyrinogen Decarboxylase | 1990 |
Treatment of hepatic coma and hepatorenal syndrome. Mechanism of action of L-dopa and aramine.
Topics: Adult; Brain Chemistry; Carbon Isotopes; Cardiac Output; Dihydroxyphenylalanine; Female; Hepatic Encephalopathy; Humans; Kidney Diseases; Liver Diseases; Male; Metaraminol; Middle Aged; Natriuresis; Neurotransmitter Agents; Octopamine; Phenethylamines; S-Adenosylmethionine; Sympathetic Nervous System; Synapses | 1972 |
[SAM-dependent transmethylation in hepatopathies of the aged].
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Creatine Kinase; Female; Humans; L-Lactate Dehydrogenase; Lipoproteins; Liver Diseases; Liver Function Tests; Male; Methylation; Middle Aged; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine | 1972 |
[S-adenosylmethionine (SAM) in geriatric therapy].
Topics: Age Factors; Aged; Arteriosclerosis; Blood Protein Disorders; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Liver Diseases; Male; Middle Aged; S-Adenosylmethionine; Serum Albumin | 1973 |
[Various effects of SAM dependent transmethylations in hepatology].
Topics: Adenosine; Biopsy; Chronic Disease; Fatty Liver; Hepatitis; Humans; Injections, Intraperitoneal; Lipid Metabolism; Liver Cirrhosis; Liver Diseases; Liver Glycogen; Methionine; Methylation; S-Adenosylmethionine | 1972 |
[Preliminary clinico-geriatric trials of S-adenosylmethionine (coenzyme of biologic transmethylation)].
Topics: Adenosine; Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Female; Humans; Injections, Intramuscular; Liver Diseases; Male; Mental Disorders; Methionine; S-Adenosylmethionine | 1972 |