Compounds > s-adenosylmethionine
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s-adenosylmethionine and Hyperhomocysteinemia

s-adenosylmethionine has been researched along with Hyperhomocysteinemia in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's21 (42.86)29.6817
2010's25 (51.02)24.3611
2020's3 (6.12)2.80

Authors

AuthorsStudies
Chen, LQ; Chen, RY; Chen, XQ; Li, XZ; Lin, Q; Shen, YY; Wu, HY; Xu, QY; Zhu, XM; Zhu, Y1
Rosas-Rodríguez, JA; Valenzuela-Soto, EM1
Castro, R; Florindo, C; Heil, SG; Huang, NK; Mattie, FJ; Neuberger, T; Ross, AC; Tavares de Almeida, I; van Zelst, B; Whalen, CA1
Ingenbleek, Y1
Cella, PS; da Silva, LECM; Deminice, R; Jordao, AA; Riberio, DF1
McCully, KS1
Cueto, R; Huang, X; Ji, Y; Lavallee, M; Li, X; Li, YF; Lopez, J; Shan, HM; Wang, H; Yang, WY; Yang, X; Yu, C; Zhang, L1
Deng, J; Dong, H; Shen, Y; Xie, Z; Xiong, L; Zhang, P; Zhao, G1
Devlin, AM; Glier, MB; Green, TJ1
Chrudinová, M; Demianová, Z; Jiráček, J; Kořínek, M; Mládková, J; Selicharová, I1
Campion, J; Cordero, P; Martinez, JA; Milagro, FI1
Cui, W; Liu, J; Sun, X; Xie, X; Zhang, D; Zhu, Y1
Comparotto, H; Deminice, R; Jordao, AA1
Choi, HS; Choi, YJ; Kim, SK; Kwak, HC; Lee, BH; Sim, WC; Yin, HQ1
Cavallaro, RA; Desiderio, C; Di Napoli, A; Fuso, A; Gervasoni, J; Giardina, B; Nicolia, V; Persichilli, S; Scarpa, S1
Huang, H; Huang, W; Ling, W; Peng, C; Su, X; Wu, X; Xia, M; Xiao, Y; Zhang, J1
Bodis, M; Geisel, J; Herrmann, M; Herrmann, W; Hübner, U; Kirsch, SH; Laufs, U; Pusceddu, I; Wagenpfeil, S; Werner, C1
Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Parvez, F; Peters, BA; Shahriar, H; Siddique, AB; Uddin, MN1
Bhatia, P; Singh, N1
Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL1
de Jonge, R; Helbing, WA; Ottenkamp, J; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; van Zelst, BD1
Belin, N; Delabar, JM; Ducros, V; Hamelet, J; Janel, N; Noll, C; Paul, JL1
Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Tami, A; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M1
Deussen, A; Henle, T; Herrmann, M; Pexa, A; Taban-Shomal, O1
Devlin, AM; Green, TJ; Innis, SM; McMahon, JA; Skeaff, CM; Venn, BJ; Williams, SM1
Garrow, TA; Gupta, S; Jiracek, J; Kruger, WD; Li, L; Rozen, R; Schalinske, KL; Strakova, J; Williams, KT1
Blom, HJ; Choi, SW; Corrocher, R; Friso, S; Girelli, D; Guarini, P; Martinelli, N; Olivieri, O; Pizzolo, F; Stanzial, AM1
Dilger, RN; Garrow, TA; Gupta, S; Kruger, WD; Li, L; Strakova, J; Tryon, K1
Beattie, JH; Duthie, SJ; Gordon, MJ; McNeil, CJ; Pirie, LP1
Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G1
Gong, H; Jiang, Y; Shi, Y; Sun, T; Sun, W; Wang, J; Wei, J; Yang, B; Zhang, H1
Aleliunas, RE; Bottiglieri, T; Devlin, AM; Glier, MB; Ngai, YF; Sulistyoningrum, DC1
Finkelstein, JD1
Favier, A; Galan, P; Guilland, JC; Hercberg, S; Potier de Courcy, G1
Di Rocco, A; Werner, P2
Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S1
Fukada, S; Kawagishi, H; Morita, T; Sekiya, A; Sugiyama, K1
Fukada, S; Morita, T; Setoue, M; Sugiyama, K1
Blom, HJ; Boers, GH; Heil, SG; Riksen, NP; Smulders, Y1
Bottiglieri, T; Cross, JC; Elmore, CL; Gravel, RA; Krupenko, NI; Krupenko, SA; Leclerc, D; Matthews, RG; Rozen, R; Watson, ED; Wu, X1
Elmore, CL; Matthews, RG1
Bottiglieri, T; Devlin, AM; Innis, SM; Lentz, SR; Singh, R; Wade, RE1
Calamandrei, G; Cavallaro, RA; Coluccia, P; D'Anselmi, F; Fuso, A; Nicolia, V; Ricceri, L; Scarpa, S1
Dudman, NP; Fu, W; Perry, MA; Wang, XL; Young, K1
Blache, D; Durand, P; Loreau, N; Lussier-Cacan, S; Prost, M1
Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD1
Amores-Sánchez, MI; Medina, M; Urdiales, JL1
Delabar, U; Kloor, D; Luippold, G; Mühlbauer, B; Osswald, H1

Reviews

9 review(s) available for s-adenosylmethionine and Hyperhomocysteinemia

ArticleYear
The glycine betaine role in neurodegenerative, cardiovascular, hepatic, and renal diseases: Insights into disease and dysfunction networks.
    Life sciences, 2021, Nov-15, Volume: 285

    Topics: Betaine; Cardiovascular Diseases; Cell Size; Humans; Hyperhomocysteinemia; Kidney Diseases; Liver Diseases; Neurodegenerative Diseases; Osmolar Concentration; S-Adenosylmethionine

2021
Lean Body Mass Harbors Sensing Mechanisms that Allow Safeguarding of Methionine Homeostasis.
    Nutrients, 2017, Sep-20, Volume: 9, Issue:9

    Topics: Betaine-Homocysteine S-Methyltransferase; Biomarkers; Body Composition; Body Mass Index; Cystathionine beta-Synthase; Diet, Protein-Restricted; Dietary Proteins; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Methionine; S-Adenosylmethionine

2017
Methyl nutrients, DNA methylation, and cardiovascular disease.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:1

    Topics: Amino Acids; Atherosclerosis; Cardiovascular Diseases; Cysteine; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Status; Risk Factors; S-Adenosylmethionine; Vitamin B Complex

2014
Role of S-adenosylhomocysteine in cardiovascular disease and its potential epigenetic mechanism.
    The international journal of biochemistry & cell biology, 2015, Volume: 67

    Topics: Atherosclerosis; Diabetes Mellitus; Endothelium, Vascular; Epigenesis, Genetic; Humans; Hyperhomocysteinemia; Kidney Diseases; Obesity; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine

2015
Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression.
    Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:6

    Topics: Cysteine; Depression; Homocysteine; Humans; Hyperhomocysteinemia; Neurotoxicity Syndromes; S-Adenosylmethionine

2015
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
    Pathologie-biologie, 2003, Volume: 51, Issue:2

    Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency

2003
The many flavors of hyperhomocyst(e)inemia: insights from transgenic and inhibitor-based mouse models of disrupted one-carbon metabolism.
    Antioxidants & redox signaling, 2007, Volume: 9, Issue:11

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cystathionine beta-Synthase; Disease Models, Animal; Ferredoxin-NADP Reductase; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Models, Biological; Molecular Structure; S-Adenosylhomocysteine; S-Adenosylmethionine

2007
Impaired homocysteine metabolism and atherothrombotic disease.
    Laboratory investigation; a journal of technical methods and pathology, 2001, Volume: 81, Issue:5

    Topics: Age Factors; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Models, Chemical; Risk Factors; S-Adenosylmethionine; Sex Factors

2001
Roles of homocysteine in cell metabolism: old and new functions.
    European journal of biochemistry, 2001, Volume: 268, Issue:14

    Topics: Cardiovascular Diseases; Cell Physiological Phenomena; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nervous System Malformations; Pregnancy; Pregnancy Complications; RNA, Transfer, Amino Acyl; S-Adenosylmethionine

2001

Trials

4 trial(s) available for s-adenosylmethionine and Hyperhomocysteinemia

ArticleYear
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.
    The Journal of nutrition, 2015, Volume: 145, Issue:10

    Topics: Adult; Bangladesh; Biomarkers; Cohort Studies; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Folic Acid; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Intention to Treat Analysis; Male; Middle Aged; Patient Dropouts; S-Adenosylhomocysteine; S-Adenosylmethionine

2015
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.
    The British journal of nutrition, 2010, Volume: 103, Issue:11

    Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins

2010
Folic acid effects on s-adenosylmethionine, s-adenosylhomocysteine, and DNA methylation in patients with intermediate hyperhomocysteinemia.
    Journal of the American College of Nutrition, 2011, Volume: 30, Issue:1

    Topics: Adult; Aged; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex

2011
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation

2005

Other Studies

36 other study(ies) available for s-adenosylmethionine and Hyperhomocysteinemia

ArticleYear
Proteinuria as a presenting sign of combined methylmalonic acidemia and homocysteinemia: case report.
    BMC medical genetics, 2020, 09-21, Volume: 21, Issue:1

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Base Sequence; Carnitine; Child, Preschool; DNA; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Proteinuria

2020
No Effect of Diet-Induced Mild Hyperhomocysteinemia on Vascular Methylating Capacity, Atherosclerosis Progression, and Specific Histone Methylation.
    Nutrients, 2020, Jul-23, Volume: 12, Issue:8

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cytokines; Diet; Disease Progression; DNA Methylation; Epigenesis, Genetic; Histones; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mice; Mice, Knockout; Pilot Projects; Plaque, Atherosclerotic; S-Adenosylmethionine

2020
Acute exercise alters homocysteine plasma concentration in an intensity-dependent manner due increased methyl flux in liver of rats.
    Life sciences, 2018, Mar-01, Volume: 196

    Topics: Animals; Body Weight; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine Adenosyltransferase; Methylation; Physical Conditioning, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Swimming

2018
    Annals of clinical and laboratory science, 2018, Volume: 48, Issue:1

    Topics: Atherosclerosis; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Melatonin; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12

2018
Identification of homocysteine-suppressive mitochondrial ETC complex genes and tissue expression profile - Novel hypothesis establishment.
    Redox biology, 2018, Volume: 17

    Topics: Animals; Cardiovascular Diseases; Electron Transport Chain Complex Proteins; Gene Expression Regulation; Humans; Hyperhomocysteinemia; Kidney; Lung; Mice; Mitochondria; Organ Specificity; Risk Factors; S-Adenosylmethionine; Spleen

2018
Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice.
    Annals of clinical and translational neurology, 2019, Volume: 6, Issue:8

    Topics: Animals; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Postoperative Cognitive Complications; Postoperative Period; Preoperative Period; Risk Factors; S-Adenosylmethionine; Vitamin B 12

2019
Effects of hyperhomocysteinemia and betaine-homocysteine S-methyltransferase inhibition on hepatocyte metabolites and the proteome.
    Biochimica et biophysica acta, 2013, Volume: 1834, Issue:8

    Topics: Apolipoprotein A-I; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Blotting, Western; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; Electrophoresis, Gel, Two-Dimensional; Fibrinogen; Hepatocytes; Homocysteine; Humans; Hyperhomocysteinemia; Liver Neoplasms; Male; Metabolomics; Middle Aged; Protein Multimerization; Proteome; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2013
Maternal methyl donors supplementation during lactation prevents the hyperhomocysteinemia induced by a high-fat-sucrose intake by dams.
    International journal of molecular sciences, 2013, Dec-16, Volume: 14, Issue:12

    Topics: Animals; Body Weight; Diet, High-Fat; Dietary Sucrose; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Female; Homocysteine; Hyperhomocysteinemia; Lactation; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylmethionine

2013
Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:1

    Topics: Angiotensin II; Animals; Binding Sites; CCCTC-Binding Factor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; DNA Methylation; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; S-Adenosylmethionine; Sp1 Transcription Factor; Telomerase; Telomere; Telomere Shortening; Time Factors; Transfection; Tumor Suppressor Protein p53

2015
Whey protein supplementation increases methionine intake but not homocysteine plasma concentration in rats.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2015, Volume: 40, Issue:1

    Topics: Advanced Oxidation Protein Products; Animals; Biomarkers; Caseins; Dietary Supplements; Glutathione; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Methionine; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Random Allocation; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Whey Proteins

2015
L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats.
    The Journal of nutrition, 2015, Volume: 145, Issue:2

    Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Dietary Supplements; Energy Intake; Ethanol; Fatty Liver, Alcoholic; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; S-Adenosylmethionine; Serine; Triglycerides

2015
Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 44, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Chromatography; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; S-Adenosylmethionine; Sulfhydryl Compounds; Superoxide Dismutase

2015
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
    European journal of nutrition, 2016, Volume: 55, Issue:5

    Topics: Aged; Blood Cells; Calcium; Cross-Sectional Studies; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Telomere; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D

2016
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
    The Journal of nutritional biochemistry, 2016, Volume: 35

    Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium

2016
Maternal global methylation status and risk of congenital heart diseases.
    Obstetrics and gynecology, 2008, Volume: 112, Issue:2 Pt 1

    Topics: Adult; Biomarkers; Case-Control Studies; Child; Down Syndrome; Female; Heart; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Infant; Linear Models; Methylation; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine

2008
Resveratrol supplementation worsen the dysregulation of genes involved in hepatic lipid homeostasis observed in hyperhomocysteinemic mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:1

    Topics: Animals; Apolipoprotein A-I; Cystathionine beta-Synthase; Dietary Supplements; Gene Expression Regulation; Genotype; Hyperhomocysteinemia; Lipid Metabolism; Liver; Mice; Phosphatidylcholine-Sterol O-Acyltransferase; Resveratrol; S-Adenosylhomocysteine; S-Adenosylmethionine; Scavenger Receptors, Class B; Stilbenes

2009
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.
    Bone, 2009, Volume: 44, Issue:3

    Topics: Aged; Animals; Bone and Bones; Collagen; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Myocardium; Osteoporosis; Porosity; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Stress, Mechanical

2009
Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model.
    Acta physiologica (Oxford, England), 2009, Volume: 197, Issue:1

    Topics: Analysis of Variance; Animal Feed; Animals; Cardiovascular Diseases; Dietary Supplements; Disease Models, Animal; Female; Homocystine; Hyperhomocysteinemia; Kidney; Liver; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Statistics, Nonparametric; Tissue Distribution

2009
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
    Nutrition research (New York, N.Y.), 2010, Volume: 30, Issue:7

    Topics: Amino Acids; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine beta-Synthase; Diet; Enzyme Inhibitors; Glycine N-Methyltransferase; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine

2010
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:7

    Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine

2011
Nutritional B vitamin deficiency disrupts lipid metabolism causing accumulation of proatherogenic lipoproteins in the aorta adventitia of ApoE null mice.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:7

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Connective Tissue; Diet, Atherogenic; Disease Models, Animal; Fatty Acids; Hyperhomocysteinemia; Lipid Metabolism; Lipoproteins; Liver; Male; Mice; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Severity of Illness Index; Vitamin B Deficiency

2012
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
    European journal of nutrition, 2013, Volume: 52, Issue:3

    Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine

2013
The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice.
    Acta biochimica et biophysica Sinica, 2012, Volume: 44, Issue:10

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Cholesterol, Dietary; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Homocysteine; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Male; Methionine; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides

2012
Tissue-specific relationship of S-adenosylhomocysteine with allele-specific H19/Igf2 methylation and imprinting in mice with hyperhomocysteinemia.
    Epigenetics, 2013, Volume: 8, Issue:1

    Topics: Alleles; Animals; Base Sequence; Body Weight; Brain; Crosses, Genetic; Diet; DNA Methylation; Female; Genetic Loci; Genomic Imprinting; Homocysteine; Hyperhomocysteinemia; Insulin-Like Growth Factor II; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Organ Specificity; RNA, Long Noncoding; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity

2013
Methionine metabolism in liver diseases.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:5

    Topics: Humans; Hyperhomocysteinemia; Liver; Liver Diseases; Methionine; S-Adenosylmethionine

2003
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
    Neurology, 2004, Feb-24, Volume: 62, Issue:4

    Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylation; Parkinson Disease; S-Adenosylmethionine; Vitamin B Complex

2004
Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats.
    Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:8

    Topics: Adenine; Animals; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Enzyme Activation; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors

2006
Dietary eritadenine suppresses guanidinoacetic Acid-induced hyperhomocysteinemia in rats.
    The Journal of nutrition, 2006, Volume: 136, Issue:11

    Topics: Adenine; Animals; Diet; Glycine; Hyperhomocysteinemia; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine

2006
DNA methylation status is not impaired in treated cystathionine beta-synthase (CBS) deficient patients.
    Molecular genetics and metabolism, 2007, Volume: 91, Issue:1

    Topics: Chromatography, Liquid; Cystathionine beta-Synthase; DNA; DNA Methylation; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization

2007
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
    Molecular genetics and metabolism, 2007, Volume: 91, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine

2007
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.
    Neurology, 2007, Apr-24, Volume: 68, Issue:17

    Topics: Antiparkinson Agents; Carbon; Catechol O-Methyltransferase Inhibitors; Catechols; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Nitriles; Parkinson Disease; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Time Factors; Vitamin B 12; Vitamin B 6

2007
Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia.
    The Journal of biological chemistry, 2007, Dec-21, Volume: 282, Issue:51

    Topics: Animals; Cystathionine beta-Synthase; DNA Methylation; Fatty Acids; Gene Silencing; Heterozygote; Hyperhomocysteinemia; Linoleoyl-CoA Desaturase; Lipid Metabolism; Liver; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Promoter Regions, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine

2007
B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice.
    Molecular and cellular neurosciences, 2008, Volume: 37, Issue:4

    Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Gene Expression Regulation; Hyperhomocysteinemia; Male; Mice; Mice, Transgenic; Presenilin-1; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Deficiency

2008
Interrelations between plasma homocysteine and intracellular S-adenosylhomocysteine.
    Biochemical and biophysical research communications, 2000, Apr-29, Volume: 271, Issue:1

    Topics: Adult; Aged; Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Erythrocytes; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tissue Distribution; Vascular Diseases

2000
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
    Circulation research, 2001, Jun-08, Volume: 88, Issue:11

    Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System

2001
Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine.
    Biochemical pharmacology, 2002, Feb-15, Volume: 63, Issue:4

    Topics: Adenosine; Animals; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Ischemia; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine

2002