s-adenosylmethionine has been researched along with Folic Acid Deficiency in 83 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 13 (15.66) | 18.7374 |
1990's | 18 (21.69) | 18.2507 |
2000's | 32 (38.55) | 29.6817 |
2010's | 19 (22.89) | 24.3611 |
2020's | 1 (1.20) | 2.80 |
Authors | Studies |
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Huang, G; Huang, L; Li, W; Li, Z; Ren, Q; Yan, J; Yan, R; Zhang, G; Zhang, Q; Zhou, D | 1 |
Arning, E; Bahous, RH; Bottiglieri, T; Caudill, MA; Christensen, KE; Deng, L; Hou, W; Jerome-Majewska, LA; Malysheva, OV; Rozen, R | 1 |
Chang, S; Li, B; Li, R; Liang, L; Liu, C; Niu, B; Qin, C; Wang, L; Wang, X; Zhang, L; Zhang, M; Zhang, T | 1 |
Cande, WZ; Guan, Q; Hammond, MC; Iavarone, AT; Li, F; Rine, J; Sadhu, MJ; Sales-Lee, J | 1 |
Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Levy, D; Liu, X; Niedzwiecki, MM; Parvez, F; Siddique, AB; Slavkovich, V | 1 |
Koenig, JE; Montgomery, SE; Sepehry, AA; Wangsgaard, JD | 1 |
Huang, G; Li, W; Liu, H; Wilson, JX; Yu, M; Zhang, M; Zhang, X | 1 |
Koehler, P; Kopp, M; Morisset, R; Rychlik, M | 1 |
Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
Han, T; James, SR; Karpf, AR; Melnyk, S; Pogribny, IP; Tryndyak, VP | 1 |
Bunout, D; de la Maza, MP; Hirsch, S; Leiva, L; Llanos, M; Montequin, MJ; Pinardi, G; Ronco, AM | 1 |
Miller, AL | 1 |
Chao, WH; Crivello, NA; D'Anci, KE; Rosenberg, IH; Selhub, J; Shukitt-Hale, B; Smith, DE; Troen, AM | 1 |
Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M | 1 |
Chan, A; Rogers, E; Shea, TB | 1 |
Chan, A; Rogers, EJ; Shea, TB; Tchantchou, F | 1 |
Fenech, M | 1 |
Abratte, CM; Caudill, MA; Shin, W; Vermeylen, F; Yan, J | 1 |
Burren, K; Copp, AJ; De Castro, SC; Greene, ND; Leung, KY; Rozen, R; Savery, D | 1 |
Baba, T; Kobayashi, Y; Matsumoto, M; Murai, H; Nishimura, N; Nohara, K; Sano, T; Suzuki, T; Tateishi, Y | 1 |
Wagner, C | 1 |
Hwang, PH; Lian, L; Zavras, AI | 1 |
Halsted, CH; Medici, V | 1 |
Anderson, OS; Dolinoy, DC; Sant, KE | 1 |
Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G | 1 |
Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
Duncan, TM; Nijhout, HF; Reed, MC | 1 |
Stephen, AM; Sun, D; Wollin, A | 1 |
Deng, L; Hiou-Tim, F; James, SJ; Li, E; Melnyk, S; Oakes, C; Pogribny, I; Rozen, R; Sibani, S; Trasler, J | 1 |
Favier, A; Galan, P; Guilland, JC; Hercberg, S; Potier de Courcy, G | 1 |
Finnell, RH; James, SJ; Le, XC; Lu, X; Melnyk, S; Selhub, J; Spiegelstein, O; Troen, A | 1 |
Cavallaro, RA; D'Anselmi, F; Fuso, A; Scarpa, S; Seminara, L | 1 |
Graves, M; Ortiz, D; Rogers, E; Shea, TB; Tchantchou, F | 1 |
Blair, IA; Brown, KS; Huang, Y; Jian, W; Lu, ZY; Whitehead, AS | 1 |
Toohey, JI | 1 |
Shea, TB | 1 |
Chan, A; Shea, TB | 3 |
Tchantchou, F | 1 |
Herrmann, W; Obeid, R | 1 |
Esfandiari, F; French, SW; Halsted, CH; Villanueva, JA; Wong, DH; You, M | 1 |
Alberto, JM; Audonnet-Blaise, S; Blaise, SA; Daval, JL; Guéant, JL | 1 |
Devaraj, S; Esfandiari, F; French, SW; Halsted, CH; Villanueva, JA; White, ME | 1 |
Alsaraby, A; Chan, AY; Shea, TB | 1 |
Chan, A; Graves, V; Rozen, R; Shea, TB; Tchantchou, F | 1 |
Martínez-Frías, ML | 1 |
Reynolds, EH; Stramentinoli, G | 1 |
Carney, MW; Reynolds, EH; Toone, BK | 1 |
Brown, L; Sourial, NA | 1 |
Poirier, LA; Shivapurkar, N | 1 |
Dang, CV | 1 |
James, SJ; Pogribny, IP; Poirier, LA | 1 |
Christman, JK; Cravo, ML; Fleet, JC; Kim, YI; Mason, JB; Ordovas, J; Salomon, RN; Selhub, J; Smith, D | 1 |
García-Cuevas, M; Pérez-Olleros, L; Ruiz-Roso, B; Varela-Moreiras, G | 1 |
Kennedy, DG; Kennedy, S; Molloy, AM; Scott, JM; Weir, DG | 1 |
Poirier, LA | 1 |
Miller, JW; Nadeau, MR; Selhub, J; Smith, D; Smith, J | 1 |
Miller, JW; Nadeau, MR; Selhub, J; Smith, D | 1 |
Balaghi, M; Horne, DW; Wagner, C; Woodward, SC | 1 |
Metz, J | 1 |
Balaghi, M; Horne, DW; Wagner, C | 1 |
Clifford, AJ; Ellis, WG; Gietzen, DW; Gospe, SM; Lunetta, JM; Miller, JW; Selhub, J; Summers, PJ | 1 |
Basnakian, AG; James, SJ; Kim, YI; Mason, JB; Miller, JW; Pogribny, IP; Selhub, J | 1 |
Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
Duthie, SJ | 1 |
Scott, JM; Weir, DG | 1 |
Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK | 1 |
Brand, GM; Duthie, SJ; Grant, G; Narayanan, S | 1 |
Bailey, LB; Cerda, JJ; Hutson, AD; Kauwell, GP; Rampersaud, GC | 1 |
Deng, L; Hiou-Tim, F; James, SJ; Melnyk, S; Pogribny, IP; Rozen, R; Sibani, S; Trasler, J; Wang, W | 1 |
Choi, SW; Ghandour, H; Lin, BF; Mason, JB; Selhub, J | 1 |
Grantham, PH; Poirier, LA; Rogers, AE | 1 |
Petri, WA; Poirier, LA | 1 |
Blackwell, LA; Grover, TA; Middaugh, LD; Zemp, JW | 1 |
Buehring, YS; Poirier, LA; Stokstad, EL | 1 |
Bell, IR; Berkes, S; Morrow, FD; Perrone, G; Read, M | 1 |
Balaghi, M; Wagner, C | 1 |
Henning, SM; McKee, RW; Swendseid, ME | 1 |
Bottiglieri, T; Carney, MW; Chary, TK; Godfrey, P; Laundy, M; Reynolds, EH; Toone, BK | 1 |
Abou-Saleh, MT; Coppen, A | 1 |
Ordonez, LA; Wurtman, RJ | 1 |
15 review(s) available for s-adenosylmethionine and Folic Acid Deficiency
Article | Year |
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The effect of S-adenosylmethionine on cognitive performance in mice: an animal model meta-analysis.
Topics: Alzheimer Disease; Animals; Cognition; Diet; Dietary Supplements; Folic Acid Deficiency; Mice; Models, Animal; Nootropic Agents; S-Adenosylmethionine | 2014 |
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2008 |
Folate, DNA damage and the aging brain.
Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil | 2010 |
Vitamin-dependent methionine metabolism and alcoholic liver disease.
Topics: Alcoholism; Animals; Epigenomics; Ethanol; Folic Acid Deficiency; Gene Expression Regulation; Humans; Liver; Liver Diseases, Alcoholic; Malnutrition; Methionine; Models, Animal; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamins | 2011 |
Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation.
Topics: Carbon; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid Deficiency; Humans; Nutritional Status; S-Adenosylmethionine; Vitamin B Complex | 2012 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency | 2003 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine metabolism and various consequences of folate deficiency.
Topics: Apolipoproteins E; Brain; DNA Methylation; Folic Acid Deficiency; Glutathione Transferase; Homocysteine; Humans; Oxidative Stress; S-Adenosylmethionine | 2006 |
The biochemical structure and function of methylenetetrahydrofolate reductase provide the rationale to interpret the epidemiological results on the risk for infants with Down syndrome.
Topics: Cystathionine beta-Synthase; Down Syndrome; Female; Flavin-Adenine Dinucleotide; Flavins; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Risk Factors; S-Adenosylmethionine; Structure-Activity Relationship | 2008 |
Methyl group deficiency in hepatocarcinogenesis.
Topics: Animals; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Methylation; Oncogenes; S-Adenosylmethionine | 1994 |
Folate, alcohol, methionine, and colon cancer risk: is there a unifying theme?
Topics: Alcohol Drinking; Animals; Colonic Neoplasms; DNA; Ethanol; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Risk Factors; S-Adenosylmethionine | 1994 |
Folic acid deficiency and cancer: mechanisms of DNA instability.
Topics: Animals; Chromosome Breakage; Colorectal Neoplasms; Cricetinae; DNA; DNA Methylation; DNA Repair; Female; Folic Acid Deficiency; Humans; Male; Proto-Oncogenes; Rats; S-Adenosylmethionine | 1999 |
Brain function in the elderly: role of vitamin B12 and folate.
Topics: Aged; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Transmethylation in depression.
Topics: Depressive Disorder; Folic Acid Deficiency; Humans; Methionine Adenosyltransferase; S-Adenosylmethionine; Transferases | 1988 |
The biology of folate in depression: implications for nutritional hypotheses of the psychoses.
Topics: Anorexia Nervosa; Biogenic Amines; Brain; Depressive Disorder; Diet; Folic Acid; Folic Acid Deficiency; Homocystinuria; Humans; Models, Theoretical; Pellagra; Pterins; S-Adenosylmethionine; Schizophrenia; Tryptophan; Vitamin B 12 Deficiency | 1986 |
4 trial(s) available for s-adenosylmethionine and Folic Acid Deficiency
Article | Year |
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Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men.
Topics: Adolescent; Adult; Choline; Choline Deficiency; Diet; DNA Damage; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid Deficiency; Genetic Markers; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Nutrition Policy; Nutritional Requirements; Polymorphism, Genetic; S-Adenosylmethionine; Young Adult | 2010 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women.
Topics: Aged; Aged, 80 and over; Dietary Supplements; DNA; DNA Methylation; DNA-Cytosine Methylases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Least-Squares Analysis; Leukocytes; Middle Aged; Nutrition Policy; S-Adenosylmethionine; Scintillation Counting; Statistics, Nonparametric | 2000 |
64 other study(ies) available for s-adenosylmethionine and Folic Acid Deficiency
Article | Year |
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SAM/SAH Mediates Parental Folate Deficiency-Induced Neural Cell Apoptosis in Neonatal Rat Offspring: The Expression of Bcl-2, Bax, and Caspase-3.
Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Female; Folic Acid; Folic Acid Deficiency; Male; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2023 |
Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.
Topics: Animals; Congenital Abnormalities; Diet; Disease Models, Animal; DNA Methylation; Female; Fetal Development; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Genotype; Ligases; Liver; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Multifunctional Enzymes; Placenta; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pregnancy, Animal; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 2018 |
Low Maternal Dietary Folate Alters Retrotranspose by Methylation Regulation in Intrauterine Growth Retardation (IUGR) Fetuses in a Mouse Model.
Topics: Animals; Disease Models, Animal; DNA Methylation; Female; Fetal Growth Retardation; Fetus; Folic Acid; Folic Acid Deficiency; Long Interspersed Nucleotide Elements; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Placenta; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 2019 |
Nutritional control of epigenetic processes in yeast and human cells.
Topics: Epigenesis, Genetic; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Histones; Humans; Infant, Newborn; K562 Cells; Methionine; Methylation; Neural Tube Defects; Pregnancy; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Species Specificity | 2013 |
Interaction of plasma glutathione redox and folate deficiency on arsenic methylation capacity in Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Glutathione; Glutathione Disulfide; Humans; Male; Methylation; Methyltransferases; Middle Aged; Oxidation-Reduction; S-Adenosylmethionine | 2014 |
Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Gene Silencing; Hippocampus; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Presenilin-1; Promoter Regions, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA | 2015 |
Stable Isotope Dilution Assays for Clinical Analyses of Folates and Other One-Carbon Metabolites: Application to Folate-Deficiency Studies.
Topics: Animals; Chickens; Deuterium; Folic Acid; Folic Acid Deficiency; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet.
Topics: Animals; Brain; Diet, Reducing; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Folic Acid Deficiency; Homocysteine; Male; Methionine; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Regulatory Factor X Transcription Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Transcription Factors | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.
Topics: Animals; Brain; Cognition Disorders; Dietary Supplements; Folic Acid Deficiency; Homocystine; Lecithins; Male; Maze Learning; Methionine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Experimental folate and vitamin B12 deficiency does not alter bone quality in rats.
Topics: Animals; Biomarkers; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Remodeling; Disease Models, Animal; Female; Folic Acid Deficiency; Homocysteine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2009 |
Dietary deficiency in folate and vitamin E under conditions of oxidative stress increases phospho-tau levels: potentiation by ApoE4 and alleviation by S-adenosylmethionine.
Topics: Animals; Apolipoprotein E4; Folic Acid Deficiency; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Oxidative Stress; Phosphorylation; S-Adenosylmethionine; tau Proteins; Vitamin E Deficiency | 2009 |
Dietary deficiency increases presenilin expression, gamma-secretase activity, and Abeta levels: potentiation by ApoE genotype and alleviation by S-adenosyl methionine.
Topics: Alleles; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Apolipoproteins E; Enzyme Activation; Folic Acid Deficiency; Gene Expression Regulation; Genotype; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Presenilin-1; S-Adenosylmethionine; Vitamin E Deficiency | 2009 |
Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation.
Topics: Animals; Carbon; DNA-Binding Proteins; Female; Fibroblasts; Folic Acid; Folic Acid Deficiency; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Mutant Strains; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymidine Monophosphate; Transcription Factors | 2010 |
Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner.
Topics: Animals; Arsenites; Carcinogens; Choline Deficiency; Deoxycytidine; Diet; DNA; DNA Methylation; DNA Modification Methylases; Female; Folic Acid Deficiency; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Sodium Compounds | 2011 |
Some more comments on 'folate deficiency in chronic pancreatitis'.
Topics: Folic Acid Deficiency; Glycine N-Methyltransferase; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Pancreatitis, Chronic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesis.
Topics: Alcohol Drinking; Aldehyde Dehydrogenase 1 Family; Carcinogenesis; Cytochrome P-450 CYP2E1; DNA; Ethanol; Folic Acid Antagonists; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Isoenzymes; Mouth Neoplasms; Nucleotides; Retinal Dehydrogenase; Risk; S-Adenosylmethionine | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Moderate folate deficiency influences polyamine synthesis in rats.
Topics: Animals; Biogenic Polyamines; Brain; Folic Acid; Folic Acid Deficiency; Intestinal Mucosa; Liver; Male; Putrescine; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Spermidine; Spermine | 2002 |
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice.
Topics: Animals; Cadherins; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Exons; Folic Acid; Folic Acid Deficiency; Mice; Mice, Inbred C57BL; Mutation; Neoplasms; Promoter Regions, Genetic; S-Adenosylmethionine; Tumor Suppressor Protein p53 | 2003 |
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice.
Topics: Animals; Arsenates; Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Cacodylic Acid; Carrier Proteins; Cross-Over Studies; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Deficiency; Male; Mice; Mice, Knockout; Receptors, Cell Surface; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Brain; Cell Line, Tumor; Culture Media, Serum-Free; DNA Methylation; Endopeptidases; Folic Acid Deficiency; Gene Expression; Homocysteine; Humans; Membrane Proteins; Presenilin-1; Promoter Regions, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2005 |
Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge: relevance to age-related neurodegeneration.
Topics: Acetylcysteine; Animals; Apolipoproteins E; Cell Line, Tumor; Dietary Supplements; Disease Models, Animal; Folic Acid Deficiency; Glutathione; Glutathione Synthase; Maze Learning; Mice; Mice, Knockout; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Tubercidin; Vitamin E Deficiency | 2004 |
Mild folate deficiency induces a proatherosclerotic phenotype in endothelial cells.
Topics: Atherosclerosis; Cell Division; Cell Line; Chemokine CCL2; DNA Methylation; Endothelium, Vascular; Folic Acid Deficiency; Gene Expression; Humans; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Folate, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Reactive Oxygen Species; S-Adenosylmethionine | 2006 |
Dietary and genetically-induced oxidative stress alter tau phosphorylation: influence of folate and apolipoprotein E deficiency.
Topics: Alzheimer Disease; Animals; Apolipoproteins E; Brain; Diet; Folic Acid Deficiency; Frontal Lobe; Hypothalamus; Mice; Mice, Inbred C57BL; Neurofibrillary Tangles; Oxidative Stress; Phosphorylation; S-Adenosylmethionine; tau Proteins; Vitamin E Deficiency | 2006 |
Supplementation with apple juice attenuates presenilin-1 overexpression during dietary and genetically-induced oxidative stress.
Topics: Acetylcholine; Age Factors; Alzheimer Disease; Animals; Antioxidants; Apolipoproteins E; Beverages; Brain; Disease Models, Animal; DNA Methylation; Folic Acid Deficiency; Gene Expression Regulation; Humans; Malus; Mice; Mutation; Neuroprotective Agents; Oxidative Stress; Presenilin-1; Reactive Oxygen Species; S-Adenosylmethionine; Vitamin E Deficiency | 2006 |
Folate deprivation increases presenilin expression, gamma-secretase activity, and Abeta levels in murine brain: potentiation by ApoE deficiency and alleviation by dietary S-adenosyl methionine.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Apolipoproteins E; Brain; Dietary Supplements; Folic Acid Deficiency; Food, Formulated; Iron, Dietary; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Presenilins; S-Adenosylmethionine; Up-Regulation; Vitamin E Deficiency | 2007 |
Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy.
Topics: Aquaporins; Brain; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Muscular Dystrophy, Duchenne; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
S-adenosylmethionine attenuates hepatic lipid synthesis in micropigs fed ethanol with a folate-deficient diet.
Topics: Adiponectin; AMP-Activated Protein Kinase Kinases; Animals; Down-Regulation; Enzyme Activation; Ethanol; Fatty Liver, Alcoholic; Feeding Behavior; Folic Acid Deficiency; Food, Formulated; Intra-Abdominal Fat; Lipids; Lipogenesis; Liver; Methionine; Nutritional Support; Omentum; Protein Kinases; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1; Swine; Swine, Miniature | 2007 |
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Choline Deficiency; Cystathionine beta-Synthase; Female; Folic Acid; Folic Acid Deficiency; Food, Formulated; Glutathione; Homocysteine; Hypoxia; Liver; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Wistar; Riboflavin; Riboflavin Deficiency; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Deficiency | 2007 |
S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet.
Topics: Animals; Body Weight; Disease Models, Animal; Ethanol; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Linear Models; Liver; Liver Diseases, Alcoholic; Male; Methionine; Necrosis; Oxidative Stress; S-Adenosylmethionine; Swine; Swine, Miniature | 2007 |
Folate deprivation increases tau phosphorylation by homocysteine-induced calcium influx and by inhibition of phosphatase activity: Alleviation by S-adenosyl methionine.
Topics: Calcium; Cell Line, Tumor; Drug Interactions; Enzyme Inhibitors; Folic Acid Deficiency; Homocysteine; Humans; N-Methylaspartate; Neuroblastoma; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; S-Adenosylmethionine; tau Proteins | 2008 |
Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Acetylcholine; Aggression; Aging; Animals; Apolipoproteins E; Cognition; Folic Acid; Folic Acid Deficiency; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Random Allocation; S-Adenosylmethionine | 2008 |
Folic acid, S-adenosylmethionine and affective disorder.
Topics: Brain; Depressive Disorder; Folic Acid Deficiency; Humans; Neurotransmitter Agents; S-Adenosylmethionine | 1983 |
Methylation and mood.
Topics: Anemia, Megaloblastic; Brain; Depressive Disorder; Emotions; Folic Acid Deficiency; Humans; Methylation; S-Adenosylmethionine; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency | 1984 |
Regulation of cobalamin and folate metabolism by methionine in human bone marrow cultures.
Topics: Bone Marrow Cells; Cells, Cultured; Deoxyuridine; Folic Acid Deficiency; Glutathione; Humans; Methionine; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1983 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
Tobacco-alcohol amblyopia: a proposed biochemical basis for pathogenesis.
Topics: Alcoholism; Amblyopia; Animals; Biotransformation; Cyanides; Deficiency Diseases; Folic Acid Deficiency; Humans; Models, Biological; S-Adenosylmethionine; Smoking; Thiamine Deficiency; Vitamin B 12 Deficiency | 1981 |
Differential sensitivity to loss of cytosine methyl groups within the hepatic p53 gene of folate/methyl deficient rats.
Topics: Animals; Base Sequence; Cytosine; Folic Acid Deficiency; Genes, p53; Liver; Male; Methylation; Molecular Sequence Data; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1995 |
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats.
Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genes, myc; Liver; Male; Methionine; Methylation; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1995 |
Effects of ageing on folate metabolism in rats fed a long-term folate deficient diet.
Topics: Aging; Animals; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
Effects of the disruption of transmethylation in the central nervous system: an animal model.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Brain; Cystathionine; Depressive Disorder; Folic Acid Deficiency; Liver; Methylation; Methyltransferases; Plasma; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B Deficiency | 1994 |
Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism.
Topics: Animals; Ethionine; Folic Acid Deficiency; Homocysteine; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1994 |
Vitamin B-6 deficiency vs folate deficiency: comparison of responses to methionine loading in rats.
Topics: Animals; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Vitamin B 6 Deficiency | 1994 |
Pancreatic one-carbon metabolism in early folate deficiency in rats.
Topics: Analysis of Variance; Animals; Cytoplasmic Granules; Folic Acid; Folic Acid Deficiency; Glycine N-Methyltransferase; Jejunum; Male; Methyltransferases; Pancreas; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1993 |
Pathogenesis of cobalamin neuropathy: deficiency of nervous system S-adenosylmethionine?
Topics: Child, Preschool; Folic Acid; Folic Acid Deficiency; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Hepatic one-carbon metabolism in early folate deficiency in rats.
Topics: Animals; Cytosol; Folic Acid; Folic Acid Deficiency; Glycine N-Methyltransferase; Liver; Male; Methyltransferases; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Weaning | 1993 |
Behavioral and neurochemical changes in folate-deficient mice.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Blood Cell Count; Body Weight; Brain; Brain Chemistry; Caudate Nucleus; Feeding Behavior; Female; Folic Acid Deficiency; Hypothalamus; Mice; Muscle, Skeletal; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Cord | 1995 |
Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene.
Topics: Animals; Base Sequence; DNA; DNA Damage; DNA Methylation; Exons; Folic Acid; Folic Acid Deficiency; Genes, Suppressor; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Suppressor Protein p53 | 1997 |
DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats.
Topics: Animals; Choline Deficiency; Colon; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice.
Topics: Animals; Biomarkers; Choline Deficiency; Diet; DNA Methylation; Folic Acid Deficiency; Intestinal Neoplasms; Methionine; Mice; Neoplasms; Precancerous Conditions; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2002 |
The effects of a marginally lipotrope-deficient diet on the hepatic levels of S-adenosylmethionine and on the urinary metabolites of 2-acetylaminofluorene in rats.
Topics: 2-Acetylaminofluorene; Animals; Benzopyrene Hydroxylase; Choline Deficiency; Diet; Female; Fluorenes; Folic Acid Deficiency; Glutathione; Hydroxyacetylaminofluorene; Lipotropic Agents; Liver; Male; Methionine; Microsomes, Liver; Nitroanisole O-Demethylase; Rats; S-Adenosylmethionine; Sex Factors | 1977 |
A methionine-reversible folate deficiency in rats following the acute administration of diethylnitrosamine and alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Animals; Choline; Diet; Diethylnitrosamine; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Liver; Male; Methionine; Nitrosamines; Rats; S-Adenosylmethionine; Thiocyanates; Time Factors | 1977 |
Neurochemical and behavioral effects of diet related perinatal folic acid restriction.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain; Diet; Escape Reaction; Female; Folic Acid; Folic Acid Deficiency; Liver; Mice; Organ Size; Pregnancy; S-Adenosylmethionine; Stress, Physiological | 1976 |
Folate deficiency in the livers of diethylnitrosaminetreated rats.
Topics: Animals; Diethylnitrosamine; Folic Acid Deficiency; Glutamates; In Vitro Techniques; Liver; Male; Methionine; Methylation; Nitrosamines; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1976 |
Low thyroxine levels in female psychiatric inpatients with riboflavin deficiency: implications for folate-dependent methylation.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Hospitalization; Humans; Male; Mental Disorders; Middle Aged; Pyridoxine; Riboflavin; Riboflavin Deficiency; S-Adenosylmethionine; Thiamine; Thyroid Function Tests; Thyroxine; Vitamin B 12 | 1992 |
Methyl group metabolism in the pancreas of folate-deficient rats.
Topics: Animals; Body Weight; Diet; Folic Acid; Folic Acid Deficiency; Male; Organ Size; Pancreas; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1992 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Folic acid deficiency and methyl group metabolism in rat brain: effects of L-dopa.
Topics: Animals; Body Weight; Brain; Dihydroxyphenylalanine; Folic Acid; Folic Acid Deficiency; Kidney; Liver; Male; Methionine; Organ Size; Organ Specificity; Rats; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 1974 |