Page last updated: 2024-08-23

s-adenosylmethionine and Down Syndrome

s-adenosylmethionine has been researched along with Down Syndrome in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Jonge, R; Helbing, WA; Ottenkamp, J; Steegers, EA; Steegers-Theunissen, RP; van Driel, LM; van Zelst, BD1
Andria, G; Castegna, A; Iacobazzi, F; Iacobazzi, V; Infantino, V; Scala, I; Spera, I1
Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR1
Duncan, TM; Nijhout, HF; Reed, MC1
Bermejo, E; Castro, M; Desviat, LR; Leal, F; Mansilla, E; Martínez-Fernández, ML; Martínez-Frías, ML; Pérez, B; Prieto, D; Rodríguez, L; Rodríguez-Pinilla, E; Ugarte, M1
Martínez-Frías, ML1
Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P1

Reviews

1 review(s) available for s-adenosylmethionine and Down Syndrome

ArticleYear
The biochemical structure and function of methylenetetrahydrofolate reductase provide the rationale to interpret the epidemiological results on the risk for infants with Down syndrome.
    American journal of medical genetics. Part A, 2008, Jun-01, Volume: 146A, Issue:11

    Topics: Cystathionine beta-Synthase; Down Syndrome; Female; Flavin-Adenine Dinucleotide; Flavins; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Risk Factors; S-Adenosylmethionine; Structure-Activity Relationship

2008

Other Studies

6 other study(ies) available for s-adenosylmethionine and Down Syndrome

ArticleYear
Maternal global methylation status and risk of congenital heart diseases.
    Obstetrics and gynecology, 2008, Volume: 112, Issue:2 Pt 1

    Topics: Adult; Biomarkers; Case-Control Studies; Child; Down Syndrome; Female; Heart; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Infant; Linear Models; Methylation; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine

2008
Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's syndrome.
    Molecular genetics and metabolism, 2011, Volume: 102, Issue:3

    Topics: Adolescent; Carrier Proteins; Cell Line, Transformed; Child; Child, Preschool; Cytosol; Down Syndrome; Glutathione; Humans; Infant; Methylation; Mitochondria; S-Adenosylmethionine

2011
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:10

    Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult

2012
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins

2013
Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome?
    American journal of medical genetics. Part A, 2006, May-01, Volume: 140, Issue:9

    Topics: Case-Control Studies; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation; Polymorphism, Single Nucleotide; Regression Analysis; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine

2006
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
    American journal of human genetics, 2001, Volume: 69, Issue:1

    Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12

2001