s-adenosylmethionine has been researched along with Diabetes Mellitus, Type 2 in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (9.09) | 29.6817 |
| 2010's | 38 (57.58) | 24.3611 |
| 2020's | 22 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cabrera, D; Falcón-Pérez, JM; Kollmus, H; Pilzner, C; Schughart, K; van Liempd, S | 1 |
| An, ZN; Ge, MH; Jiang, DW; Liu, C; Shen, XL; Wei, DZ; Xing, XJ; Zheng, DM | 1 |
| Almanza-Aguilera, E; Alonso-Gómez, Á; Arós, F; Clish, CB; Corella, D; Dennis, C; Estruch, R; Fiol, M; Gómez-Gracia, E; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Lapetra, J; Li, J; Liang, L; Martínez-González, MÁ; Razquin, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wittenbecher, C | 1 |
| An, Z; Jiang, D; Liu, C; Wei, D; Xing, X; Zheng, D | 1 |
| Fang, ZZ; Gao, XQ; Li, X; Liu, X; Wang, WY | 1 |
| Amiano, P; Ardanaz, E; Chajes, V; Gunter, MJ; Huerta, JM; Hultdin, J; Huybrechts, I; Jakszyn, P; Johnson, T; Katzke, V; Keski-Rahkonen, P; Krogh, V; Pokharel, P; Redondo-Sánchez, D; Rothwell, JA; Sacerdote, C; Sandanger, TM; Santucci de Magistris, M; Scalbert, A; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Viallon, V; Wedekind, R; Weiderpass, E; Winkvist, A | 1 |
| Che, M; Huang, R; Jin, D; Lai, M; Li, H; Mao, G; Wang, H; Wang, Y; Xia, Z; Zhang, Z; Zhao, S; Zheng, C; Zuo, J | 1 |
| Arjmand, B; Asadi, M; Dehghanbanadaki, H; Dilmaghani-Marand, A; Emamgholipour, S; Ghasemi, E; Ghodssi-Ghassemabadi, R; Hosseinkhani, S; Khoshniat, M; Larijani, B; Najjar, N; Panahi, N; Razi, F; Rezaei, N; Taghizadeh, H | 1 |
| Armstrong, P; Buse, JB; Green, JB; Hernandez, AF; Holman, RR; Ilkayeva, O; McGarrah, RW; McGuire, DK; Mentz, RJ; Newgard, CB; Nguyen, M; Peterson, ED; Regan, JA; Sattar, N; Shah, SH; Sjöström, CD; Sourij, H; Standl, E; Truby, LK; Zheng, Y | 1 |
| Alisjahbana, B; Hankemeier, T; Harms, AC; Joosten, SA; Ottenhoff, THM; Sahiratmadja, E; van Crevel, R; Vrieling, F | 1 |
| Han, Y; Li, S; Li, Y; Qin, Y; Si, X; Sun, D; Sun, W; Tang, C; Yu, X; Zhan, T; Zhang, J; Zhang, K; Zhao, Q | 1 |
| Beers-Stet, FS; Celis-Morales, C; Ghauharali-van der Vlugt, K; Gill, JMR; Goorden, SMI; Hof, MH; Muilwijk, M; van Valkengoed, IGM; Vaz, FM | 1 |
| Cao, YF; Chen, JX; Fang, ZZ; Feng, XF; Gu, M; Huang, T; Li, J; Luo, HH; Sun, D; Sun, XY; Yang, X; Zeng, J; Zhao, S | 1 |
| Al Majdoub, M; Balderas Arroyo, C; Berggren, J; Groop, L; Hedenbro, J; Herzog, K; Lindqvist, A; Spégel, P; Wierup, N | 1 |
| Ching, J; Gunther, SH; Khoo, CM; Kovalik, JP; Lee, JJ; Sim, X; Tai, ES; van Dam, RM | 1 |
| Bönhof, GJ; Knebel, B; Kotzka, J; Roden, M; Straßburger, K; Strom, A; Szendroedi, J; Ziegler, D | 1 |
| Babio, N; Bhupathiraju, SN; Clish, CB; Corella, D; Dennis, C; Drouin-Chartier, JP; Estruch, R; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Razquin, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Toledo, E; Wittenbecher, C | 1 |
| Hu, R; Li, X; Li, Y; Liang, Y; Liu, Y; Xu, W | 1 |
| Balasubramanyam, A; Bennet, R; Caducoy, E; Gaba, R; Hsu, JW; Jahoor, F; Keene, KR; Lernmark, A; Mehta, PB; Mulukutla, SN; Patel, SG; Peacock, WF | 1 |
| Abcouwer, SF; Afshinnia, F; Byun, J; Fort, PE; Gardner, TW; Kretzler, M; Looker, HC; Michailidis, G; Nelson, RG; Pennathur, S; Rajendiran, TM; Roger, JE; Shan, Y; Soni, T | 1 |
| Plomgaard, P; Weigert, C | 1 |
| Aichler, M; Alexandrov, T; Borgmann, D; Buck, A; Feuchtinger, A; Fox, JEM; Hrabe de Angelis, M; Jastroch, M; Keipert, S; Krumsiek, J; Light, PE; Lyon, J; MacDonald, PE; Mueller, NS; Neschen, S; Palmer, A; Sun, N; Tschöp, MH; Walch, A | 1 |
| Bouchouirab, FZ; Carpentier, AC; Dubé, J; Fortin, M; Noll, C | 1 |
| Al Rijjal, D; Batchuluun, B; Bhattacharjee, A; Burdett, E; Eversley, JA; Gunderson, EP; Liu, Y; Mohan, H; Prentice, KJ; Wheeler, MB | 1 |
| Caballero, AE; Duggirala, R; González-Chávez, A; Herrera-Rosas, A; Ibarra-González, I; León-Hernández, M; López-Alvarenga, JC; Mummidi, S; Romero-Ibarguengoitia, ME; Serratos-Canales, MF; Vadillo-Ortega, F | 1 |
| Ärnlöv, J; Berne, C; Broeckling, CD; Castillejo-Lopez, C; Cook, NL; Fall, T; Ganna, A; Giedraitis, V; Hetty, S; Ingelsson, E; Lind, L; Nowak, C; Prenni, JE; Salihovic, S; Shen, X; Sundström, J | 1 |
| Arós, F; Bulló, M; Clish, C; Corella, D; Dennis, C; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hu, FB; Lapetra, J; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Zheng, Y | 1 |
| Agrawal, M; Apovian, CM; Belkina, AC; Cacicedo, JM; Corkey, BE; Habib, C; Ip, BC; Jones, AR; Kern, PA; Lauffenburger, DA; Nicholas, DA; Nikolajczyk, BS; Panneerseelan-Bharath, L; Persky, L; Proctor, EA; Raval, F; Sainz-Rueda, N; Sullivan, PG; Van Nostrand, SC; Zhu, M | 1 |
| Adamski, J; Boeing, H; Drogan, D; Floegel, A; Pischon, T; Prehn, C; Schulze, MB; von Ruesten, A | 1 |
| Baldwin, A; Blewett, H; Guzman, RP; O, K; Taylor, CG; Weighell, W; Wright, B; Zahradka, P | 1 |
| Fiedler, GM; Kovacs, P; Leichtle, AB; Mai, M; Stumvoll, M; Tönjes, A | 1 |
| Affolter, A; Clanachan, AS; Hersberger, M; Lemieux, H; Lou, PH; Lucchinetti, E; Warren, BE; Zaugg, M; Zhang, L | 1 |
| Adams, SH; Huang, S; Hwang, DH; Knotts, TA; McCoin, CS; Ono-Moore, KD; Rutkowsky, JM; Schneider, D; Singh, S | 1 |
| Chen, L; Han, X; Ji, L; Zhang, C; Zhang, X | 1 |
| Anderson, SG; Banerjee, M; Broadhurst, DI; Brown, M; Cooper, GJ; Cruickshank, JK; Dunn, WB; Goodacre, R; Kell, DB | 1 |
| Ciapaite, J; Houten, SM; Nicolay, K; Prompers, JJ; van den Broek, NM; Wessels, B | 1 |
| Bowden, D; D'Agostino, RB; Il'yasova, D; Spasojevic, I; Wagenknecht, LE; Wang, F; Watkins, S | 1 |
| Adamski, J; de Mutsert, R; den Heijer, M; le Cessie, S; Mook-Kanamori, DO; Prehn, C; Rensen, PC; Rosendaal, FR; Suhre, K; van Dijk, KW | 1 |
| Aguilar-Salinas, CA; Cruz-Bautista, I; Del Bosque-Plata, L; Pallares-Méndez, R | 1 |
| Bao, Y; Gao, P; Hong, CS; Jia, W; Luo, P; Tu, Y; Wei, L; Xu, G; Yin, P; Yu, H; Zhang, P; Zhao, X; Zhuang, Z | 1 |
| Barsch, A; Fuchser, J; Haas, J; Knebel, B; Kotzka, J; Lange, S; Lehr, S; Mack, S; Müller-Wieland, D; Schiller, M; Zurek, G | 1 |
| Gao, X; Hu, FB; Hu, Y; Jin, Q; Li, H; Li, R; Liang, L; Lin, X; Liu, Y; Ma, Y; Sun, L; Wang, F; Wu, J; Yao, P; Zeng, R; Zhang, H | 1 |
| Ambler, GK; Hollak, CE; Houten, SM; Miller, SR; Murgatroyd, PR; Napolitano, A; Nunez, DJ; Schooneman, MG; Soeters, MR; Tan, CY; Vidal-Puig, A; Virtue, S | 1 |
| Abate, N; Asghar, R; Brasier, AR; Camacho-Hughes, M; Chondronikola, M; Dillon, EL; Durham, WJ; Porter, C; Sheffield-Moore, M; Sidossis, L; Tuvdendorj, D; Volpi, E; Wu, Z; Zhang, X; Zhao, Y | 1 |
| Brøns, C; Hellgren, LI; Newgard, CB; Ribel-Madsen, A; Ribel-Madsen, R; Vaag, AA | 1 |
| Adams, SH; Burnett, DJ; Campbell, C; Casazza, GA; Chandler, CJ; Fernandez, JR; Fiehn, O; Garvey, WT; Harper, ME; Hoppel, CL; Hughen, RW; Hunter, GR; Keim, NL; Light, AR; Newman, JW; Souza, EC; Zhang, J | 1 |
| Adams, SH; Garvey, WT; Hoppel, CL; Hwang, DH; Lok, KH; Minkler, PE; Newman, JW; Wong, SW; Zhao, L | 1 |
| Arias, S; Bain, JR; Bawa, B; Bose, M; Gorroochurn, P; Haqq, A; Laferrère, B; Lien, L; Muehlbauer, MJ; Newgard, CB; Reilly, D; Shah, SH; Stevens, RD; Svetkey, LP; Swerdlow, N; Teixeira, J; Wenner, BR | 1 |
| Arslanian, SA; Bacha, F; Chace, DH; de las Heras, J; DeJesus, VR; Lee, S; Michaliszyn, SF; Mihalik, SJ; Vockley, J | 1 |
| Brockman, DA; Chen, X; Gallaher, DD | 1 |
| Bagosi, Z; Bene, J; Bujtor, Z; Gasztonyi, B; Márton, M; Melegh, B; Mohás, M; Oroszlán, T; Wittmann, I | 1 |
| Jiang, N; Kong, Q; Li, S; Liu, F; Wang, H; Xiao, Y; Yu, C; Yun, L; Zhu, X | 1 |
| ALjohani, A; Assadi-Porter, F; Burhans, MS; Kalyesubula, M; Liu, X; Ntambi, JM; Selen, ES | 1 |
| Hoffman, BG; Vanderkruk, B | 1 |
| Boldizhar, P; Derbak, M | 1 |
| Alhonen, L; Asara, JM; Banks, AS; Bhanot, S; Cen, Y; Gong, F; Kahn, BB; Kong, D; Kraus, D; Monia, BP; Peroni, OD; Pirinen, E; Puigserver, P; Pulinilkunnil, TC; Rodgers, JT; Sauve, AA; Wang, YC; Yang, Q; Zhang, L | 1 |
| Noureddin, M; Rinella, ME | 1 |
| Booker, SJ; Landgraf, BJ; McCarthy, EL | 1 |
| Walker, AK | 1 |
| Cho, BJ; Choi, SH; Chung, MH; Jang, HC; Kim, M; Kim, TH; Kim, YB; Ko, SH; Lee, IK; Lim, S; Moon, MK; Park, HS; Park, KS; Shin, H | 1 |
| Cao, J; Combs, GF; Jackson, MI; Uthus, E; Zeng, H | 1 |
| Becker, A; Bouter, LM; Dekker, JM; Heine, RJ; Henry, RM; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Stehouwer, CD; Teerlink, T; Zweegman, S | 1 |
| Becker, A; Bouter, LM; Dekker, JM; Heine, RJ; Henry, RM; Jakobs, C; Kostense, PJ; Nijpels, G; Smulders, YM; Spijkerman, AM; Stehouwer, CD; Teerlink, T | 1 |
| Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H | 1 |
| Cho, YM; Choi, SW; Friso, S; Jin, CJ; Kim, MS; Lee, HK; Lee, KU; Pak, YK; Park, HK; Park, KS | 1 |
| Bouter, LM; Dekker, JM; Heine, RJ; Jakobs, C; Nijpels, G; Polak, BC; Stehouwer, CD; Stolk, RP; Teerlink, T; Van Hecke, MV | 1 |
7 review(s) available for s-adenosylmethionine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Mitochondrial metabolites predict adverse cardiovascular events in individuals with diabetes.
Topics: Biomarkers; Cardiovascular Diseases; Cardiovascular System; Diabetes Mellitus, Type 2; Exenatide; Humans; Mitochondria | 2023 |
Do diabetes and obesity affect the metabolic response to exercise?
Topics: AMP-Activated Protein Kinases; Blood Glucose; Carnitine; Diabetes Mellitus, Type 2; Exercise; Fatty Acids; Glucose; Glycogen; Humans; Liver; Muscle, Skeletal; Obesity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction | 2017 |
Metabolomics in diabetes, a review.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Metabolomics; Obesity; Predictive Value of Tests | 2016 |
Metabolism as a central regulator of β-cell chromatin state.
Topics: Acetyl Coenzyme A; Chromatin; Citric Acid Cycle; Diabetes Mellitus, Type 2; Glucose; Histones; Homeostasis; Humans; Insulin; Insulin-Secreting Cells; Ketoglutaric Acids; Mitochondria; NAD; Oxidative Phosphorylation; Oxidative Stress; Protein Processing, Post-Translational; S-Adenosylmethionine | 2021 |
Nonalcoholic Fatty liver disease, diabetes, obesity, and hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Chemoprevention; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Incidence; Inflammation; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Leptin; Liver Neoplasms; Metformin; Non-alcoholic Fatty Liver Disease; Obesity; Risk Factors; S-Adenosylmethionine; Toll-Like Receptors | 2015 |
Radical S-Adenosylmethionine Enzymes in Human Health and Disease.
Topics: Carbon-Carbon Lyases; Diabetes Mellitus, Type 2; Gene Expression; Heart Defects, Congenital; Histone Acetyltransferases; Humans; Intracellular Signaling Peptides and Proteins; Iron-Sulfur Proteins; Metal Metabolism, Inborn Errors; Mutation; Nerve Tissue Proteins; Neurodegenerative Diseases; Nuclear Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Proteins; S-Adenosylmethionine; Thioctic Acid; tRNA Methyltransferases | 2016 |
1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver.
Topics: Animals; Carbon Cycle; Diabetes Mellitus, Type 2; Fatty Liver; Humans; Lipogenesis; Phosphatidylcholines; S-Adenosylmethionine | 2017 |
9 trial(s) available for s-adenosylmethionine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Plasma acylcarnitines and risk of incident heart failure and atrial fibrillation: the Prevención con dieta mediterránea study.
Topics: Atrial Fibrillation; Cardiovascular Diseases; Carnitine; Diabetes Mellitus, Type 2; Diet, Mediterranean; Heart Failure; Humans; Mediterranea; Nuts; Obesity; Olive Oil; Risk Factors | 2022 |
Plasma Palmitoyl-Carnitine (AC16:0) Is a Marker of Increased Postprandial Nonesterified Incomplete Fatty Acid Oxidation Rate in Adults With Type 2 Diabetes.
Topics: Adult; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Humans; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Oxidation-Reduction; Palmitoylcarnitine; Postprandial Period; Young Adult | 2018 |
Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach.
Topics: Adolescent; Adult; Amino Acids; Carnitine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Medical History Taking; Metabolomics; Middle Aged; Models, Biological; Non-alcoholic Fatty Liver Disease; Obesity | 2018 |
Type 2 diabetes is associated with postprandial amino acid measures.
Topics: Adult; Amino Acids; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Postprandial Period; Sleep | 2016 |
Assessment of plasma acylcarnitines before and after weight loss in obese subjects.
Topics: Adult; Anthropometry; Body Composition; Carnitine; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Nonesterified; Female; Glucose; Humans; Insulin Resistance; Lipolysis; Male; Middle Aged; Obesity; Oxygen; Respiration; Weight Loss; Young Adult | 2016 |
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.
Topics: Adult; Amino Acids, Branched-Chain; Carnitine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Humans; Male; Metabolic Networks and Pathways; Middle Aged; Obesity; Principal Component Analysis; Regression Analysis; Weight Loss | 2011 |
[Correction of dyslipidemia in patients with chronic hepatitis C, combined with diabetes type 2].
Topics: Antiviral Agents; Diabetes Mellitus, Type 2; Dyslipidemias; Female; Hepatitis C, Chronic; Humans; Male; Middle Aged; S-Adenosylmethionine; Treatment Outcome; Ursodeoxycholic Acid | 2014 |
Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study.
Topics: Aged; Arteriosclerosis; Carotid Arteries; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Erythrocytes; Female; Homocysteine; Humans; Male; Middle Aged; S-Adenosylmethionine; Tunica Intima; Tunica Media; Vitamin B 12; Vitamin B 6 | 2003 |
S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study.
Topics: Aged; Brachial Artery; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nitroglycerin; Regional Blood Flow; Risk Factors; S-Adenosylmethionine; Tetrahydrofolates; Ultrasonography; Vasodilation; Vasodilator Agents; Vitamin B 12; Vitamin B 6 | 2005 |
50 other study(ies) available for s-adenosylmethionine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Impaired beta-oxidation increases vulnerability to influenza A infection.
Topics: Amino Acids, Branched-Chain; Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Influenza A virus; Mice; Orthomyxoviridae Infections; Oxidation-Reduction | 2021 |
Medium & long-chain acylcarnitine's relation to lipid metabolism as potential predictors for diabetic cardiomyopathy: a metabolomic study.
Topics: Adult; Aminoimidazole Carboxamide; Animals; Biomarkers; Carnitine; Cell Line; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Female; Humans; Lipid Metabolism; Male; Mass Spectrometry; Middle Aged; Myoblasts, Cardiac; Myristic Acids; Rats; Retrospective Studies; Ribonucleosides; Risk Factors | 2021 |
Correlation between Acylcarnitine and Peripheral Neuropathy in Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Body Mass Index; Carnitine; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Risk Factors | 2022 |
Relationship Between Acylcarnitine and the Risk of Retinopathy in Type 2 Diabetes Mellitus.
Topics: Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; ROC Curve | 2022 |
Determinants of blood acylcarnitine concentrations in healthy individuals of the European Prospective Investigation into Cancer and Nutrition.
Topics: Carnitine; Diabetes Mellitus, Type 2; Fatty Acids; Humans; Neoplasms; Prospective Studies | 2022 |
Plasma acylcarnitine and diabetic retinopathy: A study from Eastern China.
Topics: Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans | 2022 |
The association between acylcarnitine and amino acids profile and metabolic syndrome and its components in Iranian adults: Data from STEPs 2016.
Topics: Adult; Carnitine; Chromatography, Liquid; Citrulline; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Iran; Metabolic Syndrome; Tandem Mass Spectrometry; Trypsin | 2023 |
Plasma metabolomics in tuberculosis patients with and without concurrent type 2 diabetes at diagnosis and during antibiotic treatment.
Topics: Adult; Amines; Anti-Bacterial Agents; Blood Proteins; Body Weight; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indonesia; Least-Squares Analysis; Male; Metabolomics; Middle Aged; Nitric Oxide Synthase; Principal Component Analysis; ROC Curve; Tandem Mass Spectrometry; Tuberculosis, Pulmonary; Young Adult | 2019 |
Targeted Metabolomics Analysis Reveals that Dietary Supranutritional Selenium Regulates Sugar and Acylcarnitine Metabolism Homeostasis in Pig Liver.
Topics: Animals; Carnitine; Diabetes Mellitus, Type 2; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Homeostasis; Hyperglycemia; Hyperinsulinism; Lipids; Liver; Male; Metabolomics; Models, Animal; Oxidation-Reduction; RNA, Messenger; Selenium; Selenomethionine; Selenoproteins; Sugars; Sus scrofa | 2020 |
Contributions of amino acid, acylcarnitine and sphingolipid profiles to type 2 diabetes risk among South-Asian Surinamese and Dutch adults.
Topics: Adult; Amino Acids; Carnitine; Diabetes Mellitus, Type 2; Ethnicity; Humans; Netherlands; Sphingolipids | 2020 |
The Association Between Acylcarnitine Metabolites and Cardiovascular Disease in Chinese Patients With Type 2 Diabetes Mellitus.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Carnitine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Metabolome; Middle Aged; Prognosis | 2020 |
Metabolic Effects of Gastric Bypass Surgery: Is It All About Calories?
Topics: Adult; Blood Glucose; Caloric Restriction; Carnitine; Diabetes Mellitus, Type 2; Fasting; Female; Gastric Bypass; Humans; Insulin; Insulin Resistance; Middle Aged; Obesity, Morbid; Postprandial Period | 2020 |
Serum acylcarnitines and amino acids and risk of type 2 diabetes in a multiethnic Asian population.
Topics: Amino Acids; Carnitine; Diabetes Mellitus, Type 2; Female; Humans; Male; Prospective Studies; Risk Factors; Singapore | 2020 |
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes.
Topics: Adult; Autonomic Nervous System Diseases; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dyslipidemias; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heart Rate; Humans; Insulin Resistance; Lipid Metabolism; Lipidomics; Lysophosphatidylcholines; Male; Middle Aged; Obesity; Phosphatidylcholines; Sphingomyelins; Young Adult | 2021 |
Walnut Consumption, Plasma Metabolomics, and Risk of Type 2 Diabetes and Cardiovascular Disease.
Topics: Amino Acids; Biomarkers; Cardiovascular Diseases; Carnitine; Diabetes Mellitus, Type 2; Humans; Juglans; Lipids; Metabolomics; Nuts; Purines; Risk Factors | 2021 |
Plasma Targeted Metabolomics Analysis for Amino Acids and Acylcarnitines in Patients with Prediabetes, Type 2 Diabetes Mellitus, and Diabetic Vascular Complications.
Topics: Amino Acids; Carnitine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Metabolomics; Prediabetic State | 2021 |
Metabolomics Profiling of Patients With A-β+ Ketosis-Prone Diabetes During Diabetic Ketoacidosis.
Topics: Adult; Amino Acids, Branched-Chain; Autoantibodies; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Female; Humans; Male; Metabolome; Metabolomics; Middle Aged | 2021 |
Diminished retinal complex lipid synthesis and impaired fatty acid β-oxidation associated with human diabetic retinopathy.
Topics: Adult; Aged; American Indian or Alaska Native; Arizona; Black or African American; Carnitine; Case-Control Studies; Ceramides; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diglycerides; Disease Progression; Esters; Female; Hispanic or Latino; Humans; Lipidomics; Male; Mass Spectrometry; Middle Aged; Mitochondria; Phosphatidylcholines; Retina; Triglycerides; White People | 2021 |
N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes.
Topics: Animals; Carnitine; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Taurine | 2017 |
Elevated Medium-Chain Acylcarnitines Are Associated With Gestational Diabetes Mellitus and Early Progression to Type 2 Diabetes and Induce Pancreatic β-Cell Dysfunction.
Topics: Adult; Animals; Carnitine; Case-Control Studies; Cell Respiration; Diabetes Mellitus, Type 2; Diabetes, Gestational; Disease Progression; Female; Glucose Intolerance; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Postpartum Period; Pregnancy | 2018 |
Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.
Topics: 3T3-L1 Cells; Aged; Animals; Carnitine; Diabetes Mellitus, Type 2; Glucose; Glucose Tolerance Test; Humans; Insulin Resistance; Lipolysis; Male; Metabolomics; Mice | 2018 |
Plasma Acylcarnitines and Risk of Type 2 Diabetes in a Mediterranean Population at High Cardiovascular Risk.
Topics: Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 2; Diet, Mediterranean; Female; Follow-Up Studies; Humans; Incidence; Male; Metabolomics; Middle Aged; Prognosis; Prospective Studies; Risk Factors; ROC Curve | 2019 |
Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes.
Topics: Adult; Aged; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Cross-Sectional Studies; Cytokines; Diabetes Mellitus, Type 2; Fatty Acids; Female; Gene Knockdown Techniques; Glycolysis; Humans; Inflammation; Lymphocyte Activation; Male; Membrane Transport Proteins; Middle Aged; Obesity; Oxidation-Reduction; Th17 Cells; Transfection; Young Adult | 2019 |
Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam.
Topics: Adult; Amino Acids; Carnitine; Chronic Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet; Feeding Behavior; Female; Hexoses; Humans; Male; Metabolome; Metabolomics; Middle Aged; Phosphatidylcholines; Risk Factors; Surveys and Questionnaires | 2013 |
Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease.
Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carnitine; Carotid Stenosis; Cholesterol; Cholesterol, LDL; Cohort Studies; Diabetes Mellitus, Type 2; Diet; Endothelium, Vascular; Fabaceae; Female; Humans; Hyperlipidemias; Hypertension; Inflammation; Isoflavones; Male; Middle Aged; Muscle, Skeletal; Peripheral Arterial Disease; Time Factors | 2013 |
Serum levels of acylcarnitines are altered in prediabetic conditions.
Topics: Adult; Aged; Blood Glucose; Body Composition; Carnitine; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Male; Middle Aged; Prediabetic State | 2013 |
Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat.
Topics: Aconitate Hydratase; Animals; Carnitine; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Disease Progression; Energy Metabolism; Fatty Acids; Fructose; Glutamic Acid; Glycolysis; Insulin Resistance; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Phosphorylation; Prediabetic State; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2014 |
Acylcarnitines activate proinflammatory signaling pathways.
Topics: Animals; Carnitine; Cell Line, Transformed; Cell Line, Tumor; Cyclooxygenase 2; Cytokines; Diabetes Mellitus, Type 2; Docosahexaenoic Acids; Enzyme Induction; Gene Silencing; Humans; Macrophage Activation; Macrophages; MAP Kinase Signaling System; Mice; Myeloid Differentiation Factor 88; Myristic Acids; Phosphorylation; Protein Processing, Post-Translational; Receptors, Pattern Recognition; Recombinant Proteins; Toll-Like Receptor 2 | 2014 |
Human serum acylcarnitine profiles in different glucose tolerance states.
Topics: Biomarkers; Blood Glucose; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Type 2; Fasting; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Male; Middle Aged; Oxidation-Reduction; Prediabetic State; Spectrometry, Mass, Electrospray Ionization | 2014 |
Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes.
Topics: Adiponectin; Adipose Tissue; Adult; Blood Glucose; Carnitine; Diabetes Mellitus, Type 2; Diabetes, Gestational; Diglycerides; Fasting; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Lipid Metabolism; Metabolome; Phospholipids; Prediabetic State; Pregnancy; Principal Component Analysis | 2014 |
Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes.
Topics: Animals; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Hypertriglyceridemia; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Metabolism; Male; Mitochondria, Muscle; Mitochondrial Diseases; Mitochondrial Turnover; Muscle, Skeletal; Obesity; Oxidative Phosphorylation; Oxidative Stress; Pioglitazone; PPAR gamma; Rats, Zucker; Thiazolidinediones | 2015 |
Urinary F2-isoprostanes and metabolic markers of fat oxidation.
Topics: Carnitine; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; F2-Isoprostanes; Fatty Acids; Female; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Oxidation-Reduction; Risk Factors; Tandem Mass Spectrometry | 2015 |
Metabolomics Study of Roux-en-Y Gastric Bypass Surgery (RYGB) to Treat Type 2 Diabetes Patients Based on Ultraperformance Liquid Chromatography-Mass Spectrometry.
Topics: Adult; Amino Acids; Bile Acids and Salts; Bilirubin; Biomarkers; Carnitine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids, Nonesterified; Female; Gastric Bypass; Hippurates; Humans; Indican; Insulin Resistance; Male; Mass Spectrometry; Metabolomics; Middle Aged; Obesity, Morbid; Oxidative Stress; Prognosis; Remission Induction; Treatment Outcome; Tryptophan; Weight Loss | 2016 |
Untargeted mass spectrometric approach in metabolic healthy offspring of patients with type 2 diabetes reveals medium-chain acylcarnitine as potential biomarker for lipid induced glucose intolerance (LGIT).
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; Carnitine; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Lipids; Male; Mass Spectrometry; Metabolome; Middle Aged; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Young Adult | 2016 |
Early Prediction of Developing Type 2 Diabetes by Plasma Acylcarnitines: A Population-Based Study.
Topics: Aged; Biomarkers; Blood Glucose; Carnitine; China; Chromatography, Liquid; Diabetes Mellitus, Type 2; Fasting; Female; Glycated Hemoglobin; Humans; Insulin; Lipid Metabolism; Logistic Models; Male; Metabolomics; Middle Aged; Mitochondria; Prospective Studies; Risk Factors; ROC Curve; Tandem Mass Spectrometry | 2016 |
Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women.
Topics: Adult; Aged; Blood Cells; Blood Glucose; Body Mass Index; Carnitine; Diabetes Mellitus, Type 2; Female; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Lipid Metabolism; Middle Aged; Overweight; Oxidation-Reduction; Palmitates; Palmitoylcarnitine | 2017 |
Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men.
Topics: Adult; Birth Weight; Carnitine; Citric Acid Cycle; Cross-Over Studies; Denmark; Diabetes Mellitus, Type 2; Diet, High-Fat; Dietary Fats; Energy Intake; Fasting; Fatty Acids; Humans; Infant, Low Birth Weight; Insulin; Insulin Resistance; Lipid Metabolism; Male; Mitochondria; Oxidation-Reduction; Randomized Controlled Trials as Topic | 2016 |
Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons.
Topics: Adenosine Triphosphate; Adult; Amino Acids, Branched-Chain; Biomarkers; Carnitine; Citric Acid Cycle; Diabetes Mellitus, Type 2; Exercise; Fatty Acids; Female; Humans; Insulin Resistance; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Neurons, Afferent; Obesity; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Weight Loss | 2017 |
Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women.
Topics: Adult; Aged; Aged, 80 and over; Black or African American; Carnitine; Citric Acid Cycle; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Ion Channels; Middle Aged; Mitochondrial Proteins; Mutation, Missense; NF-kappa B; Obesity; Oxidation-Reduction; Polymorphism, Genetic; Uncoupling Protein 3; Young Adult | 2009 |
Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: evidence for enhanced mitochondrial oxidation.
Topics: Absorptiometry, Photon; Adolescent; Amino Acids; Carnitine; Diabetes Mellitus, Type 2; Fasting; Fatty Acids; Female; Humans; Male; Obesity | 2012 |
Consumption of a high β-glucan barley flour improves glucose control and fatty liver and increases muscle acylcarnitines in the Zucker diabetic fatty rat.
Topics: Adiponectin; Animals; beta-Glucans; Blood Glucose; Body Weight; Carnitine; Cholesterol; Diabetes Mellitus, Type 2; Dietary Fiber; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver; Flour; Glucose Tolerance Test; Hordeum; Insulin; Insulin Resistance; Intestine, Small; Ketones; Liver; Obesity; Organ Size; Postprandial Period; Rats; Rats, Zucker; Thiobarbituric Acid Reactive Substances; Triglycerides | 2013 |
Similarities in serum acylcarnitine patterns in type 1 and type 2 diabetes mellitus and in metabolic syndrome.
Topics: Adult; Aged; Body Mass Index; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Young Adult | 2013 |
Metformin induces S-adenosylmethionine restriction to extend the Caenorhabditis elegans healthspan through H3K4me3 modifiers.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Diabetes Mellitus, Type 2; Histones; Longevity; Metformin; S-Adenosylmethionine | 2022 |
Hepatic oleate regulates one-carbon metabolism during high carbohydrate feeding.
Topics: Animals; Carbohydrates; Carbon; Diabetes Mellitus, Type 2; Liver; Mice; Mice, Knockout; Obesity; Oleic Acid; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine | 2023 |
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Topics: Acetyltransferases; Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Diabetes Mellitus, Type 2; Diet; Energy Metabolism; Fatty Liver; Gene Knockdown Techniques; Glucose Intolerance; Glucose Transporter Type 4; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; S-Adenosylmethionine; Sirtuin 1; Spermine; Thinness | 2014 |
Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats.
Topics: Angioplasty, Balloon; Animals; Apoptosis; Biomarkers; Carotid Artery Diseases; Cell Division; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Insulin Resistance; Male; Muscle, Smooth, Vascular; Neointima; Oxidative Stress; Rats; Rats, Inbred OLETF; S-Adenosylmethionine; Vasculitis | 2011 |
S-adenosylmethionine-dependent protein methylation is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes.
Topics: Adenosylhomocysteinase; Diabetes Mellitus, Type 2; Gene Expression Regulation; Gluconeogenesis; Glucose-6-Phosphate; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Phosphoenolpyruvate Carboxykinase (GTP); Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Selenoprotein P | 2012 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
S-adenosyl-L-methionine increases skeletal muscle mitochondrial DNA density and whole body insulin sensitivity in OLETF rats.
Topics: Aging; Animals; Diabetes Mellitus, Type 2; DNA; Feeding Behavior; Glucose; Insulin; Insulin Resistance; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Inbred OLETF; S-Adenosylmethionine; Weight Gain | 2007 |
Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study.
Topics: Aged; Aged, 80 and over; Arterioles; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Follow-Up Studies; Glucose Tolerance Test; Homocysteine; Humans; Male; Middle Aged; Retinal Diseases; Retinal Vessels; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |