Page last updated: 2024-08-23

s-adenosylmethionine and Depressive Disorder, Major

s-adenosylmethionine has been researched along with Depressive Disorder, Major in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.35)18.7374
1990's1 (2.17)18.2507
2000's11 (23.91)29.6817
2010's26 (56.52)24.3611
2020's6 (13.04)2.80

Authors

AuthorsStudies
Ahmed, AT; Arnold, M; Bhattacharyya, S; Bobo, WV; Craighead, WE; Dunlop, BW; Frye, MA; Kaddurah-Daouk, R; Krishnan, R; Liu, D; Louie, G; MahmoudianDehkordi, S; McDonald, WM; Millington, DS; Moseley, MA; Neavin, D; Riva-Posse, P; Rush, AJ; Skime, MK; Thompson, JW; Wang, L; Weinshilboum, RM; Williams, LSJ1
Ahmed, AT; Arnold, M; Baillie, RA; Bhattacharyya, S; Craighead, WE; Dunlop, BW; Frye, MA; Han, X; John-Williams, LS; Kaddurah-Daouk, R; Krishnan, R; Louie, G; MahmoudianDehkordi, S; McDonald, W; Moseley, MA; Riva-Posse, P; Rush, AJ; Skime, MK; Thompson, JW; Weinshilboum, RM1
Ferrucci, L; Gould, TD; Kadriu, B; Khadeer, M; Lovett, J; Moaddel, R; Morris, PJ; Ravichandran, S; Shardell, M; Thomas, CJ; Yuan, P; Zarate, CA1
Baldi, A; Cioffi, V; Daglia, M; Di Minno, A; El-Seedi, HR; Esposito, C; Greco, A; Khalifa, SAM; Sacchi, R; Santonastaso, S; Sperandeo, R; Ullah, H1
Adams, L; Berk, M; Bousman, C; Byrne, GJ; Chamoli, S; Cribb, L; MacDonald, P; Menon, R; Mischoulon, D; Murphy, J; Nazareth, S; Ng, CH; Oliver, G; Sarris, J; Savage, K; Stough, C2
Bernard-Negron, R; Cusin, C; Dording, CM; Fava, M; I Papakostas, G; L Carpenter, L; Ludington, E; Mischoulon, D; Price, LH; R Tyrka, A; Sakurai, H; Yeung, AS1
Cameron, BR; Ferreira, L; MacDonald, ID; Targum, SD2
Adams, L; Berk, M; Bousman, C; Byrne, GJ; Chamoli, S; Cribb, L; MacDonald, P; Menon, R; Mischoulon, D; Murphy, J; Nazareth, S; Ng, C; Oliver, G; Sarris, J; Savage, K; Stough, C1
Wilson, A1
Anheyer, D; Cramer, H; Dobos, G; Haller, H1
Popper, CW1
Baer, L; Carpenter, LL; Clain, AJ; Dording, CM; Durham, K; Fava, M; Ludington, E; Mischoulon, D; Papakostas, GI; Price, LH; Tyrka, AR; Walker, R1
Fava, M; Mischoulon, D; Papakostas, GI; Sarris, J; Vitolo, O1
Admon, R; Bogdan, R; Dillon, DG; Dougherty, DD; Fava, M; Holmes, AJ; Iosifescu, DV; Kumar, P; Mischoulon, D; Nickerson, LD; Pizzagalli, DA1
Bottiglieri, T; Brown, RP; Gerbarg, PL; Muskin, PR1
Carpenter, LL; Fava, M; Mischoulon, D; Papakostas, GI; Price, LH; Tyrka, AR1
Carpenter, LL; Fava, M; Jaeger, A; Mischoulon, D; Ng, CH; Papakostas, GI; Price, LH; Sarris, J; Tyrka, AR1
Cavuto, M; de Bartolomeis, A; De Berardis, D; Di Giannantonio, M; Di Nicola, M; Fornaro, M; Girinelli, G; Iasevoli, F; Martinotti, G; Mazza, M; Orsolini, L; Perna, G; Piersanti, M; Serroni, N; Tomasetti, C; Valchera, A1
Freeman, MP1
Filteau, MJ; Kennedy, SH; Lam, RW; Lespérance, F; Parikh, SV; Patten, SB; Ravindran, AV1
Papakostas, GI1
Deligiannidis, KM; Freeman, MP1
Cohen, LS; Fava, M; Freeman, MP; Goodness, T; Mischoulon, D; Papakostas, GI; Tedeschini, E1
Alpert, JE; Fava, M; Mischoulon, D; Papakostas, GI; Shyu, I1
Nelson, JC1
Fleisch, SB; Ryan, ND; Travis, MJ1
Alpert, JE; Dording, CM; Mischoulon, D; Papakostas, GI; Shyu, I1
Alpert, JE; Brintz, CE; Levkovitz, Y; Mischoulon, D; Papakostas, GI2
Nahas, R; Sheikh, O1
Frisch, A; Gothelf, D; Green, T; Steingart, L; Weizman, A; Zarchi, O1
Alpert, JE; Arning, E; Bottiglieri, T; Fava, M; Mischoulon, D; Papakostas, GI1
Cassiello, CF; Iovieno, N; Papakostas, GI1
Delle Chiaie, R; Pancheri, P; Scapicchio, P1
Chiaie, RD; Pancheri, P; Scapicchio, P1
Ernst, J1
Cohen, BM; Damico, KE; Goren, J; Parow, AM; Renshaw, PF; Silveri, MM; Stoll, AL; Villafuerte, RA1
Alpert, JE; Fava, M; Papakostas, GI1
Bazzan, AJ; Schaller, JL; Thomas, J1
Alpert, JE; Bottiglieri, T; Burns, A; Fava, M; Mahal, Y; Mischoulon, D; Nierenberg, AA; Papakostas, G; Petersen, T; Worthington, JJ1
Cergnul, I; Jones, K; Karpiak, SE; Mendez, D; Shippy, RA1
Alpert, JE; Bottiglieri, T; Fava, M; Kolsky, AR; Magni, G; Moore, C; Moroz, G; Nierenberg, AA; Renshaw, P; Rosenbaum, JF; Spillmann, M1
Agnoli, A; Andreoli, V; Casacchia, M; Cerbo, R1
Agnoli, A; Andreoli, V; Casacchia, M; Cerbo, R; Fazio, C1

Reviews

12 review(s) available for s-adenosylmethionine and Depressive Disorder, Major

ArticleYear
S-Adenosyl Methionine (SAMe) for Depression in Adults.
    Issues in mental health nursing, 2019, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Cost-Benefit Analysis; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Patient Acceptance of Health Care; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Treatment Outcome; Young Adult

2019
Complementary therapies for clinical depression: an overview of systematic reviews.
    BMJ open, 2019, 08-05, Volume: 9, Issue:8

    Topics: Acupuncture Therapy; Antidepressive Agents; Cognitive Behavioral Therapy; Complementary Therapies; Crocus; Curcumin; Dance Therapy; Depressive Disorder; Depressive Disorder, Major; Dietary Supplements; Drugs, Chinese Herbal; Fatty Acids, Omega-3; Humans; Hypericum; Meta-Analysis as Topic; Mindfulness; Music Therapy; Phototherapy; Plant Preparations; Qigong; S-Adenosylmethionine; Systematic Reviews as Topic; Tai Ji; Trace Elements; Vitamins; Yoga; Zinc

2019
Mood disorders in youth: exercise, light therapy, and pharmacologic complementary and integrative approaches.
    Child and adolescent psychiatric clinics of North America, 2013, Volume: 22, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Antidepressive Agents, Second-Generation; Carbidopa; Child; Complementary Therapies; Depressive Disorder, Major; Enzyme Inhibitors; Exercise Therapy; Humans; Hypericum; Integrative Medicine; Mood Disorders; Phototherapy; Phytotherapy; S-Adenosylmethionine; Treatment Outcome

2013
A comprehensive review on the efficacy of S-Adenosyl-L-methionine in Major Depressive Disorder.
    CNS & neurological disorders drug targets, 2016, Volume: 15, Issue:1

    Topics: Antidepressive Agents; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2016
Complementary and alternative medicine for perinatal depression.
    Journal of affective disorders, 2009, Volume: 112, Issue:1-3

    Topics: Acupuncture Therapy; Complementary Therapies; Depression, Postpartum; Depressive Disorder, Major; Fatty Acids, Omega-3; Female; Herbal Medicine; Humans; Hypericum; Phototherapy; Phytotherapy; Plant Extracts; Pregnancy; Pregnancy Complications; S-Adenosylmethionine

2009
Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.
    The Journal of clinical psychiatry, 2009, Volume: 70 Suppl 5

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Drug Therapy, Combination; Humans; S-Adenosylmethionine; Treatment Outcome

2009
Complementary and alternative medicine for the treatment of depressive disorders in women.
    The Psychiatric clinics of North America, 2010, Volume: 33, Issue:2

    Topics: Acupuncture Therapy; Adult; Complementary Therapies; Depressive Disorder; Depressive Disorder, Major; Exercise Therapy; Fatty Acids, Omega-3; Female; Humans; Hypericum; Phototherapy; Phytotherapy; Plant Preparations; S-Adenosylmethionine; Sex Factors; Treatment Outcome; United States

2010
Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:6

    Topics: Adult; Antidepressive Agents; Complementary Therapies; Depressive Disorder, Major; Double-Blind Method; Fatty Acids, Omega-3; Female; Humans; Male; Placebos; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Sample Size; Severity of Illness Index; Treatment Outcome

2010
Complementary and alternative medicine for the treatment of major depressive disorder.
    Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:6

    Topics: Acupuncture Therapy; Complementary Therapies; Depressive Disorder, Major; Dietary Supplements; Exercise Therapy; Fatty Acids, Omega-3; Folic Acid; Humans; Hypericum; Phytotherapy; S-Adenosylmethionine

2011
Folates and S-adenosylmethionine for major depressive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2012, Volume: 57, Issue:7

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Therapy, Combination; Evidence-Based Medicine; Humans; One-Carbon Group Transferases; Pteroylpolyglutamic Acids; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Tetrahydrofolates

2012
Alternative treatment modalities in human immunodeficiency virus/acquired immune deficiency syndrome.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Volume: 37 Suppl 2

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Complementary Therapies; Depressive Disorder, Major; HIV Infections; Humans; Peripheral Nervous System Diseases; S-Adenosylmethionine

2003
S-adenosyl-methionine in depression: a comprehensive review of the literature.
    Current psychiatry reports, 2003, Volume: 5, Issue:6

    Topics: Antidepressive Agents; Brain; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Treatment Outcome

2003

Trials

25 trial(s) available for s-adenosylmethionine and Depressive Disorder, Major

ArticleYear
Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects.
    Psychopharmacology, 2018, Volume: 235, Issue:10

    Topics: Adult; Amino Acids, Essential; Antidepressive Agents; Biogenic Amines; Carnitine; Cross-Over Studies; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Female; Glycerophospholipids; Humans; Ketamine; Lipids; Male; Metabolomics; Middle Aged; Sphingolipids; Young Adult

2018
Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate depression: A monocentric, randomized, cross-over, double-blind, placebo-controlled clinical trial.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Depression; Depressive Disorder, Major; Dietary Supplements; Double-Blind Method; Humans; Probiotics; Quality of Life; S-Adenosylmethionine

2022
S-Adenosylmethionine (SAMe) monotherapy for depression: an 8-week double-blind, randomised, controlled trial.
    Psychopharmacology, 2020, Volume: 237, Issue:1

    Topics: Adult; Antidepressive Agents; Australia; Depression; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; S-Adenosylmethionine; Treatment Outcome

2020
Dose increase of S-Adenosyl-Methionine and escitalopram in a randomized clinical trial for major depressive disorder.
    Journal of affective disorders, 2020, 02-01, Volume: 262

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; S-Adenosylmethionine; Treatment Outcome

2020
Early score fluctuation and placebo response in a study of major depressive disorder.
    Journal of psychiatric research, 2020, Volume: 121

    Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Humans; Outcome Assessment, Health Care; Placebo Effect; Psychiatric Status Rating Scales; Remission Induction; Reproducibility of Results; Research Design; S-Adenosylmethionine

2020
Adjunctive S-adenosylmethionine (SAMe) in treating non-remittent major depressive disorder: An 8-week double-blind, randomized, controlled trial.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2018, Volume: 28, Issue:10

    Topics: Adult; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Dietary Supplements; Double-Blind Method; Female; Humans; Male; Middle Aged; S-Adenosylmethionine; Treatment Failure

2018
An augmentation study of MSI-195 (S-adenosylmethionine) in Major Depressive Disorder.
    Journal of psychiatric research, 2018, Volume: 107

    Topics: Adult; Antidepressive Agents; Body Mass Index; Depressive Disorder, Major; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; S-Adenosylmethionine; Severity of Illness Index

2018
Nutraceuticals for major depressive disorder- more is not merrier: An 8-week double-blind, randomised, controlled trial.
    Journal of affective disorders, 2019, 02-15, Volume: 245

    Topics: Adult; Aged; Antidepressive Agents; Australia; Brain-Derived Neurotrophic Factor; Depressive Disorder, Major; Dietary Supplements; Double-Blind Method; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Polymorphism, Genetic; S-Adenosylmethionine; Young Adult

2019
A double-blind, randomized, placebo-controlled clinical trial of S-adenosyl-L-methionine (SAMe) versus escitalopram in major depressive disorder.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Young Adult

2014
S-adenosyl methionine (SAMe) versus escitalopram and placebo in major depression RCT: efficacy and effects of histamine and carnitine as moderators of response.
    Journal of affective disorders, 2014, Volume: 164

    Topics: Adult; Antidepressive Agents; Biomarkers; Carnitine; Citalopram; Depressive Disorder, Major; Double-Blind Method; Female; Histamine; Humans; Male; Middle Aged; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2014
Dissociable cortico-striatal connectivity abnormalities in major depression in response to monetary gains and penalties.
    Psychological medicine, 2015, Volume: 45, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Case-Control Studies; Citalopram; Corpus Striatum; Depressive Disorder, Major; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Motivation; Psychiatric Status Rating Scales; Punishment; Regression Analysis; S-Adenosylmethionine; Treatment Outcome

2015
Is S-Adenosyl Methionine (SAMe) for Depression Only Effective in Males? A Re-Analysis of Data from a Randomized Clinical Trial.
    Pharmacopsychiatry, 2015, Volume: 48, Issue:4-5

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; S-Adenosylmethionine; Sex Characteristics

2015
S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial.
    The American journal of psychiatry, 2010, Volume: 167, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder; Depressive Disorder, Major; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2010
SAMe and sexual functioning.
    European psychiatry : the journal of the Association of European Psychiatrists, 2012, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Libido; Male; Middle Aged; Penile Erection; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Surveys and Questionnaires; Treatment Outcome

2012
Effects of S-adenosylmethionine augmentation of serotonin-reuptake inhibitor antidepressants on cognitive symptoms of major depressive disorder.
    European psychiatry : the journal of the Association of European Psychiatrists, 2012, Volume: 27, Issue:7

    Topics: Adult; Aged; Antidepressive Agents; Cognition; Cognition Disorders; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Mental Recall; Middle Aged; Neuropsychological Tests; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Self Report; Surveys and Questionnaires; Treatment Outcome

2012
Effects of S-adenosylmethionine augmentation of serotonin-reuptake inhibitor antidepressants on cognitive symptoms of major depressive disorder.
    Journal of affective disorders, 2012, Volume: 136, Issue:3

    Topics: Adult; Antidepressive Agents; Cognition Disorders; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors

2012
The feasibility and safety of S-adenosyl-L-methionine (SAMe) for the treatment of neuropsychiatric symptoms in 22q11.2 deletion syndrome: a double-blind placebo-controlled trial.
    Journal of neural transmission (Vienna, Austria : 1996), 2012, Volume: 119, Issue:11

    Topics: Adolescent; Adult; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Cross-Over Studies; Depressive Disorder, Major; DiGeorge Syndrome; Double-Blind Method; Feasibility Studies; Female; Humans; Male; Mental Disorders; Psychiatric Status Rating Scales; S-Adenosylmethionine; Young Adult

2012
Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:6

    Topics: Biological Availability; Depressive Disorder, Major; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylhomocysteine; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates

2012
Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies.
    The American journal of clinical nutrition, 2002, Volume: 76, Issue:5

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylmethionine; Safety; Treatment Outcome

2002
A double-blind, randomized parallel-group, efficacy and safety study of intramuscular S-adenosyl-L-methionine 1,4-butanedisulphonate (SAMe) versus imipramine in patients with major depressive disorder.
    The international journal of neuropsychopharmacology, 2002, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Imipramine; Injections, Intramuscular; Male; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylmethionine

2002
S-adenosyl-L-methionine: effects on brain bioenergetic status and transverse relaxation time in healthy subjects.
    Biological psychiatry, 2003, Oct-15, Volume: 54, Issue:8

    Topics: Adenosine Triphosphate; Administration, Oral; Adult; Antidepressive Agents; Brain; Cerebrovascular Circulation; Depressive Disorder, Major; Drug Administration Schedule; Energy Metabolism; Female; Health Status; Humans; Magnetic Resonance Spectroscopy; Male; Models, Biological; Phosphocreatine; Phosphorus; Relaxation; S-Adenosylmethionine

2003
S-adenosyl-L-methionine (SAMe) as an adjunct for resistant major depressive disorder: an open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:6

    Topics: Adult; Cyclohexanols; Depressive Disorder, Major; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride

2004
S-adenosylmethionine (SAM-e) for the treatment of depression in people living with HIV/AIDS.
    BMC psychiatry, 2004, Nov-11, Volume: 4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Depressive Disorder, Major; Drug Administration Schedule; Female; HIV Infections; Humans; Male; Middle Aged; Personality Inventory; Psychiatric Status Rating Scales; S-Adenosylmethionine; Severity of Illness Index; Treatment Outcome

2004
Effect of s-adenosyl-l-methionine (SAMe) upon depressive symptoms.
    Journal of psychiatric research, 1976, Volume: 13, Issue:1

    Topics: Adjustment Disorders; Adult; Aged; Anxiety; Attitude; Clinical Trials as Topic; Depression; Depressive Disorder, Major; Drug Evaluation; Female; Humans; Hypochondriasis; Male; Middle Aged; Placebos; Psychomotor Disorders; Psychophysiologic Disorders; S-Adenosylmethionine; Suicide Prevention; Time Factors

1976
[Therapeutic effects and mechanism of action of S-adenosyl-L-methionine (SAM) in depressive syndromes].
    Minerva medica, 1973, Apr-30, Volume: 64, Issue:29

    Topics: Adjustment Disorders; Adrenal Glands; Adult; Aged; Animals; Bipolar Disorder; Brain; Clinical Trials as Topic; Depression; Depressive Disorder, Major; Female; Humans; Liver; Lung; Male; Middle Aged; Myocardium; S-Adenosylmethionine

1973

Other Studies

9 other study(ies) available for s-adenosylmethionine and Depressive Disorder, Major

ArticleYear
Acylcarnitine metabolomic profiles inform clinically-defined major depressive phenotypes.
    Journal of affective disorders, 2020, 03-01, Volume: 264

    Topics: Carnitine; Depressive Disorder, Major; Humans; Phenotype; Retrospective Studies

2020
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression.
    Translational psychiatry, 2021, 03-02, Volume: 11, Issue:1

    Topics: Amines; Antidepressive Agents; Carnitine; Citalopram; Depression; Depressive Disorder, Major; Humans; Lipids; Selective Serotonin Reuptake Inhibitors

2021
Failed studies should not be used to malign good treatments.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:11

    Topics: Antidepressive Agents; Citalopram; Depressive Disorder, Major; Female; Humans; Male; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors

2014
Dr. Mischoulon and colleagues reply.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:11

    Topics: Antidepressive Agents; Citalopram; Depressive Disorder, Major; Female; Humans; Male; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors

2014
Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. V. Complementary and alternative medicine treatments.
    Journal of affective disorders, 2009, Volume: 117 Suppl 1

    Topics: Acupuncture Therapy; Adult; Antidepressive Agents; Complementary Therapies; Dehydroepiandrosterone; Depressive Disorder, Major; Dietary Supplements; Exercise Therapy; Fatty Acids, Omega-3; Herbal Medicine; Humans; Hypericum; Phototherapy; Phytotherapy; S-Adenosylmethionine; Sleep Deprivation; Tryptophan; Yoga

2009
S-adenosyl methionine (SAMe) augmentation in major depressive disorder.
    The American journal of psychiatry, 2010, Volume: 167, Issue:8

    Topics: Antidepressive Agents; Depressive Disorder, Major; Drug Costs; Drug Resistance; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Treatment Outcome

2010
Discrepancy in response and remission rates for SAMe-treated patients in a double-blind, randomized clinical trial.
    The American journal of psychiatry, 2010, Volume: 167, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder, Major; Humans; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Treatment Outcome

2010
SAMe use in children and adolescents.
    European child & adolescent psychiatry, 2004, Volume: 13, Issue:5

    Topics: Adolescent; Child; Depressive Disorder, Major; Female; Humans; Injections, Intramuscular; Male; S-Adenosylmethionine; Treatment Outcome

2004
Open study of the catechol-O-methyltransferase inhibitor tolcapone in major depressive disorder.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:4

    Topics: Adult; Benzophenones; Catechol O-Methyltransferase Inhibitors; Caudate Nucleus; Choline; Depressive Disorder, Major; Female; Frontal Lobe; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nitrophenols; Personality Inventory; Reference Values; S-Adenosylmethionine; Tolcapone; Treatment Outcome

1999