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s-adenosylmethionine and Cell Transformation, Neoplastic

s-adenosylmethionine has been researched along with Cell Transformation, Neoplastic in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199012 (41.38)18.7374
1990's1 (3.45)18.2507
2000's6 (20.69)29.6817
2010's8 (27.59)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Chughtai, K; Glunde, K; Greenwood, TR; Heeren, RM; Jiang, L1
Calvisi, DF; Feo, CF; Feo, F; Pascale, RM; Simile, MM1
Arakelian, A; Attias, M; Mehdi, A; Piccirillo, CA; Rabbani, SA; Szyf, M1
Barbier-Torres, L; Fan, W; Lu, SC; Mato, JM; Murray, B1
Barve, A; Beverly, LJ; Casson, L; Ghare, S; Shah, PP; Siskind, LJ; Vega, A; Wunderlich, M1
Bhattacharjee, P; Giri, AK; Paul, S1
Bardeesy, N; Boukhali, M; Chen, T; Dyson, NJ; Gu, H; Haas, W; Hammerman, PS; Hayes, DN; Hayward, MC; Karnik, R; Kottakis, F; Li, YY; Liesa, M; Meissner, A; Nagle, JM; Nicolay, BN; Roumane, A; Shirihai, OS; Wong, KK1
Hölttä, E; Järvinen, K; Kielosto, M; Nummela, P; Yin, M1
Anglim, PP; Caballería, J; Embade, N; Fernández-Ramos, D; Finnell, RH; Gorospe, M; Laird-Offringa, IA; Lu, SC; Luka, Z; Martínez-Chantar, ML; Martínez-Lopez, N; Mato, JM; Varela-Rey, M; Vázquez-Chantada, M; Wagner, C; Woodhoo, A1
Bassoli, BK; Chagas, CE; Dagli, ML; de Souza, CA; Deminice, R; Jordão Júnior, AA; Moreno, FS; Ong, TP; Paiva, SA1
Li, TW; Lu, SC; Mato, JM; Peng, H; Xia, M; Yang, H1
Asara, G; Brignole, C; Calvisi, DF; De Miglio, MR; Feo, F; Frau, M; Muroni, MR; Pagnan, G; Pascale, RM; Pastorino, F; Ponzoni, M; Seddaiu, MA; Simile, MM1
Bozinov, D; Callaway, ES; Chapkin, RS; Davidson, LA; Finnell, RH; James, J; Kappen, C; Lupton, JR; Ma, DW; Piedrahita, JA; Salbaum, JM; Spiegelstein, O; Weeks, BR1
Chen, G; Pakneshan, P; Rabbani, SA; Shukeir, N; Szyf, M1
Coppin, JF; Qu, W; Waalkes, MP1
Hoffman, RM1
Arnaud, M; Dante, R; Niveleau, A1
Chiang, PK; Johnson, GS1
Godburn, KE; Nazar, RN; Sitz, TO; Somers, KD1
Beart, RW; Jones, PA; Nguyen, TT; Schmutte, C; Yang, AS1
Laird, PW1
Hipwell, SE; Liteplo, RG1
Boss, GR; Erbe, RW; Levitt, LJ1
Clarke, S; Deschenes, RJ; Stock, J; Vogel, JP1
Lillehaug, JR; Male, R; Refsum, H; Ueland, PM1
Balemans, MG; Ebels, I1
Gallagher, RE; Gallo, RC; Ting, RC1
Klagsbrun, M1
Borek, E; Kerr, SJ1

Reviews

7 review(s) available for s-adenosylmethionine and Cell Transformation, Neoplastic

ArticleYear
S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent.
    Cells, 2022, 01-25, Volume: 11, Issue:3

    Topics: Animals; Antiviral Agents; Betaine; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Colorectal Neoplasms; Humans; Liver Neoplasms; Male; Methionine Adenosyltransferase; Non-alcoholic Fatty Liver Disease; Rats; Ribavirin; S-Adenosylmethionine

2022
Methionine adenosyltransferases in liver cancer.
    World journal of gastroenterology, 2019, Aug-21, Volume: 25, Issue:31

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Dedifferentiation; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Down-Regulation; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Isoenzymes; Liver; Liver Neoplasms; Methionine Adenosyltransferase; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; S-Adenosylmethionine

2019
Arsenic toxicity and epimutagenecity: the new LINEage.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2017, Volume: 30, Issue:4

    Topics: Arsenic; Arsenic Poisoning; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Environmental Exposure; Epigenesis, Genetic; Folic Acid; Genome, Human; Humans; Long Interspersed Nucleotide Elements; Neoplasms; Promoter Regions, Genetic; S-Adenosylmethionine

2017
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:1-2

    Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40

1984
Mouse models in DNA-methylation research.
    Current topics in microbiology and immunology, 2000, Volume: 249

    Topics: Animals; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Mice; Mice, Knockout; S-Adenosylmethionine

2000
Physiological aspects of pineal functions in mammals.
    Physiological reviews, 1986, Volume: 66, Issue:3

    Topics: Acetylserotonin O-Methyltransferase; Animals; Biopterins; Cell Transformation, Neoplastic; Female; gamma-Aminobutyric Acid; Gonads; Indoles; Male; Mammals; Melatonin; Models, Biological; Neopterin; Neurophysins; Norepinephrine; Pineal Gland; Pituitary Hormones, Anterior; S-Adenosylhomocysteine; S-Adenosylmethionine; Seasons; Vasotocin

1986
The tRNA methyltransferases.
    Advances in enzymology and related areas of molecular biology, 1972, Volume: 36

    Topics: Animals; Bacteriophages; Base Sequence; Binding Sites; Biological Evolution; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Escherichia coli; Genetics, Microbial; Methylation; Methyltransferases; Mice; Mutation; Nucleic Acid Conformation; Organ Specificity; Rats; RNA, Transfer; S-Adenosylmethionine; Virus Replication; Viruses

1972

Other Studies

22 other study(ies) available for s-adenosylmethionine and Cell Transformation, Neoplastic

ArticleYear
Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models.
    Journal of lipid research, 2013, Volume: 54, Issue:2

    Topics: Animals; Breast Neoplasms; Carnitine; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Mass Spectrometry; Mice; Molecular Imaging; Phosphatidylcholines; Sphingomyelins

2013
S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas.
    Neoplasia (New York, N.Y.), 2023, Volume: 36

    Topics: Animals; Carcinogenesis; CD8-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Immune Checkpoint Inhibitors; Melanoma; Mice; Proto-Oncogene Proteins B-raf; S-Adenosylmethionine

2023
Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia.
    Cells, 2019, 10-25, Volume: 8, Issue:11

    Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia; Leukemia, Biphenotypic, Acute; Methionine; Methyltransferases; Oncogene Proteins, Fusion; Protein Processing, Post-Translational; S-Adenosylmethionine

2019
LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
    Nature, 2016, 11-17, Volume: 539, Issue:7629

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Cell Culture Techniques; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Gene Silencing; Genes, Tumor Suppressor; Glycine; Glycolysis; Humans; Mice; Pancreatic Ducts; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Retroelements; S-Adenosylmethionine; Serine; TOR Serine-Threonine Kinases; Transaminases

2016
Identification of integrins alpha6 and beta7 as c-Jun- and transformation-relevant genes in highly invasive fibrosarcoma cells.
    International journal of cancer, 2009, Sep-01, Volume: 125, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Animals; Biomarkers, Tumor; Blotting, Western; Cell Movement; Cell Transformation, Neoplastic; Collagen; Drug Combinations; Fibroblasts; Fibrosarcoma; Fluorescent Antibody Technique; Gene Expression Profiling; Gene Expression Regulation; Humans; Immunoenzyme Techniques; Immunoprecipitation; Integrin alpha6beta1; Integrin beta Chains; JNK Mitogen-Activated Protein Kinases; Laminin; Mice; Neoplasm Invasiveness; NIH 3T3 Cells; Oligonucleotide Array Sequence Analysis; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; S-Adenosylmethionine

2009
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
    Gastroenterology, 2010, Volume: 138, Issue:5

    Topics: 3' Untranslated Regions; Animals; Antigens, Surface; Binding Sites; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; ELAV Proteins; ELAV-Like Protein 1; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; Glycine N-Methyltransferase; Half-Life; Hepatocytes; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; Humans; Liver Neoplasms; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; RNA Interference; RNA Processing, Post-Transcriptional; RNA Stability; RNA-Binding Proteins; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Transfection

2010
Folic acid supplementation during early hepatocarcinogenesis: cellular and molecular effects.
    International journal of cancer, 2011, Nov-01, Volume: 129, Issue:9

    Topics: Animals; Apoptosis; Body Weight; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Dietary Supplements; DNA Damage; DNA Methylation; Folic Acid; Gene Expression; Genes, myc; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine

2011
Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice.
    Carcinogenesis, 2012, Volume: 33, Issue:2

    Topics: Animals; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; Dextran Sulfate; Inflammation; Interleukin-10; Interleukin-6; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-akt; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2012
Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis.
    Carcinogenesis, 2005, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Transformation, Neoplastic; Cyclin D1; Fenretinide; I-kappa B Proteins; Liposomes; Liver; Liver Neoplasms; Male; Methionine Adenosyltransferase; NF-KappaB Inhibitor alpha; NF-kappaB-Inducing Kinase; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Rats; Rats, Inbred F344; S-Adenosylmethionine; Vascular Endothelial Growth Factor A

2005
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.
    Cancer research, 2005, Feb-01, Volume: 65, Issue:3

    Topics: Animals; Azoxymethane; Carcinogens; Carrier Proteins; Cell Cycle; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Folate Receptors, GPI-Anchored; Gene Expression Profiling; Gene Silencing; Genetic Predisposition to Disease; Kidney; Male; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Receptors, Cell Surface; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylhomocysteine; S-Adenosylmethionine

2005
Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo.
    Cancer research, 2006, Sep-15, Volume: 66, Issue:18

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Genetic Therapy; Humans; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neovascularization, Pathologic; Oligonucleotides, Antisense; Plasminogen Activators; Prostatic Neoplasms; RNA, Messenger; S-Adenosylmethionine; Transfection; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2006
Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells.
    The Journal of biological chemistry, 2008, Jul-11, Volume: 283, Issue:28

    Topics: Adenosylhomocysteinase; Arsenites; Cell Line; Cell Transformation, Neoplastic; Cystathionine beta-Synthase; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Homocysteine; Humans; Male; Methionine Adenosyltransferase; Multidrug Resistance-Associated Proteins; Prostate; S-Adenosylmethionine; Sodium Compounds

2008
Effects of 5'deoxy-5'-methylthioadenosine on the metabolism of S-adenosyl methionine.
    Biochemical and biophysical research communications, 1983, Jul-18, Volume: 114, Issue:1

    Topics: Adenosine; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferases; Kidney; Kinetics; Rats; S-Adenosylmethionine; Sulfur Radioisotopes; Thionucleosides

1983
1-methylnicotinamide and NAD metabolism in normal and transformed normal rat kidney cells.
    Archives of biochemistry and biophysics, 1981, Volume: 210, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Kidney; NAD; Niacinamide; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin

1981
Significance of S-adenosylmethionine pools in the hypomethylation of ribosomal RNA during the propagation of tissue culture cells and oncogenesis.
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Animals; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Child; Fibroblasts; HeLa Cells; Humans; Kidney; Kinetics; Liver; Liver Regeneration; Male; Methylation; Osteosarcoma; Rats; Rats, Inbred Strains; RNA, Ribosomal; S-Adenosylhomocysteine; S-Adenosylmethionine

1983
Mechanisms for the involvement of DNA methylation in colon carcinogenesis.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Base Sequence; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Complementary; DNA, Neoplasm; Escherichia coli; Humans; Intestinal Mucosa; Methylation; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymidine; Uracil-DNA Glycosidase

1996
Agarose-selected variants of two human tumor cell lines exhibit altered methionine auxotrophy.
    Journal of cellular physiology, 1989, Volume: 141, Issue:3

    Topics: Cell Line; Cell Transformation, Neoplastic; Genetic Variation; Homocysteine; Humans; Melanoma; Methionine; Neuroblastoma; Nucleic Acids; S-Adenosylmethionine; Sepharose; Tumor Cells, Cultured

1989
Decreased methylation rates of DNA in SV40-transformed human fibroblasts.
    Cancer, 1986, Feb-15, Volume: 57, Issue:4

    Topics: Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Methionine; Methylation; S-Adenosylmethionine; Simian virus 40

1986
Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:13

    Topics: Animals; Cell Transformation, Neoplastic; Fibroblasts; Neoplasm Proteins; Phosphoproteins; Protein Methyltransferases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; S-Adenosylmethionine; Tumor Suppressor Protein p53

1988
Disposition of endogenous homocysteine by mouse fibroblast C3H/10T1/2 Cl 8 and the chemically transformed C3H/10T1/2 MCA Cl 16 cells following methotrexate exposure.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Culture Media; Fibroblasts; Homocysteine; Methotrexate; Methylcholanthrene; Mice; Mice, Inbred C3H; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine

1986
Transfer RNA methylase alterations in polyoma transformed rat embryo culture cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:3

    Topics: Acetates; Animals; Biological Assay; Cell Transformation, Neoplastic; Culture Techniques; Escherichia coli; Methylation; Polyomavirus; Quaternary Ammonium Compounds; Rats; RNA, Transfer; S-Adenosylmethionine; Transferases; Yeasts

1971
The contrast between the methylation of transfer ribonucleic acid in vivo and in vitro by normal and SV40 transformed 3T3 cells.
    The Journal of biological chemistry, 1972, Dec-10, Volume: 247, Issue:23

    Topics: Animals; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Chromatography; Chromatography, DEAE-Cellulose; Clone Cells; Cytoplasm; Electrophoresis; Escherichia coli; Fibroblasts; Methylation; Mice; Mice, Inbred BALB C; Oligonucleotides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Simian virus 40; Tritium

1972