Page last updated: 2024-08-23

s-adenosylmethionine and Alcoholic Liver Diseases

s-adenosylmethionine has been researched along with Alcoholic Liver Diseases in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.77)18.7374
1990's4 (7.55)18.2507
2000's25 (47.17)29.6817
2010's22 (41.51)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alikhanov, BA; Ershova, OB; Fominih, JA; Gorbacheva, IA; Ivashkin, VT; Kobalava, ZD; Maevskaya, MV; Rozanov, AV; Sander-Struckmeier, S; Sokolov, KA; Sotnikova, TI; Tolkacheva, VV; Uspenskiy, YP; Znakhyrenko, AA1
Fagoonee, S; Leone, S; Pellicano, R; Testino, G1
Andrianov, AIu; Batotsyrenov, BV; Shikalova, IA; Shilov, VV; Vasil'ev, SA1
Enbom, E; French, SW; Halsted, CH; Le, MD; Medici, V; Traum, PK1
Butov, MA; Mnikhovich, MV; Nikiforov, AA; Uzbekova, DG; Vasilevskaia, AS1
Gluud, C; Rambaldi, A3
Skvortsova, TE; Tkachenko, EI; Uspenskiĭ, IuP1
Kharbanda, KK2
Bleyle, L; Bradford, BU; Craig, CP; Koop, DR; Melnyk, S; O'Connell, TM; Pogribny, IP; Powell, CL; Rusyn, I; Threadgill, DW; Tsuchiya, M; Uehara, T1
Andringa, KK; Bailey, SM; Dickinson, DA; Eccleston, HB; Jhala, NC; King, AL; Landar, A; Mantena, SK; Squadrito, GL1
Bardag-Gorce, F; French, BA; French, SW; Li, J; Lin, A; Oliva, J1
Bardag-Gorce, F; French, BA; French, SW; Li, J; Oliva, J2
Bardag-Gorce, F; French, BA; French, SW; Li, J; Lu, SC; Oliva, J1
Albanese, A; Bowlus, CL; Devaraj, S; French, SW; Gregory, JF; Halsted, CH; Medici, V; Panacek, EA; Peerson, JM; Richards, JR; Stabler, SP; Virata, MC1
Halsted, CH; Medici, V1
Batots'orenov, BV; Loladze, AT; Shikalova, IA; Shilov, VV; Vasil'ev, SA1
Bardag-Gorce, F; Barve, S; Kharbanda, KK; Molina, PE; Osna, NA1
Andrianov, AIu; Batotsyrenov, BV; Loladze, AT; Shikalova, IA; Shilov, VV; Vasil'ev, SA1
Batotsyrenov, BV; Loladze, AT; Shikalova, IA; Shilov, VV; Vasil'ev, SA1
Dawson, D; French, BA; French, SW; Khachatoorian, R; Maloney, EM; Wang, J1
Halsted, CH2
Cederbaum, AI1
Purohit, V; Russo, D1
Lu, SC; Mato, JM; Tsukamoto, H1
Avila, MA; Corrales, FJ; del Pino, MM; García-Trevijano, ER; Latasa, MU; Martínez-Chantar, ML; Martínez-Cruz, LA; Mato, JM; Pérez-Mato, I1
Lieber, CS6
Barve, S; Chawla, R; Chen, T; Hill, DB; McClain, CJ; Song, Z; Watson, WH1
Colell, A; Fernández-Checa, JC; García-Ruiz, C1
Volchkova, EV1
Ao, Y; Dai, T; French, SW; Leng, AS; Lu, SC; Robel, RC; Wan, YJ; Wu, Y1
Lu, SC; Mato, JM1
Bailey, SM; Ballinger, S; Chamlee, L; Chhieng, D; Darley-Usmar, V; Jhala, N; Kharbanda, KK; Landar, A; Page, GP; Pinner, A; Pompilius, M; Robinson, G; Ulasova, E1
Barve, S; Deaciuc, I; Hill, D; Hote, P; Joshi-Barve, S; McClain, C; Song, Z1
Lu, SC; Martínez-Chantar, ML; Mato, JM1
Abdelmalek, MF; Barve, S; Benevenga, NJ; Halsted, CH; Kaplowitz, N; Kharbanda, KK; Liu, QY; Lu, SC; McClain, CJ; Purohit, V; Swanson, C; Zakhari, S1
Griffith, CM; Schenker, S1
Devaraj, S; Esfandiari, F; French, SW; Halsted, CH; Villanueva, JA; White, ME1
Mancinella, A1
Alvaro, D; Bini, A; Capocaccia, L; Carli, L; Furfaro, S; Gigliozzi, A; La Rosa, T; Piat, C1
Diaz Belmont, A; Dominguez Henkel, R; Uribe Ancira, F1
Barve, S; Bradford, BU; Chawla, RK; Colell, A; Deaciuc, I; Enomoto, N; Fernandez-Checa, JC; Garcia-Ruiz, C; Hill, D; Hirose, M; Ikejima, K; Ishii, H; Ishikawa, M; Joshi-Barve, S; Kaplowitz, N; Kitamura, T; Konno, A; Kono, H; Lin, M; McClain, CJ; Motomura, K; Nakamura, Y; Nelson, W; Ohata, M; Oide, H; Okamura, Y; Peter, S; Rivera, CA; Sato, N; Schmidt, J; Shimizu, H; Takei, Y; Thurman, R; Tsukamoto, H; Watson, W; Yamashina, S; Yokoyama, H1
Barrio, E; Cutrín, C; Meniño, MJ; Míguez, J; Otero, X; Pérez-Becerra, E1
Albano, O; Altomare, E; Carrieri, V; Di Padova, C; Le Grazie, C; Salerno, MT; Trizio, T; Vendemiale, G1

Reviews

27 review(s) available for s-adenosylmethionine and Alcoholic Liver Diseases

ArticleYear
WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases.
    The Cochrane database of systematic reviews, 2015, Nov-11, Issue:11

    Topics: Humans; Liver Diseases, Alcoholic; Randomized Controlled Trials as Topic; S-Adenosylmethionine

2015
Alcoholic liver disease and methionine metabolism.
    Seminars in liver disease, 2009, Volume: 29, Issue:2

    Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine

2009
Vitamin-dependent methionine metabolism and alcoholic liver disease.
    Advances in nutrition (Bethesda, Md.), 2011, Volume: 2, Issue:5

    Topics: Alcoholism; Animals; Epigenomics; Ethanol; Folic Acid Deficiency; Gene Expression Regulation; Humans; Liver; Liver Diseases, Alcoholic; Malnutrition; Methionine; Models, Animal; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamins

2011
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:1

    Topics: Animals; Antigen Presentation; Betaine; Ethanol; Hepatitis C; Humans; Interferons; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; Methyltransferases; Proteasome Endopeptidase Complex; S-Adenosylmethionine; Tumor Necrosis Factor-alpha

2013
B-Vitamin dependent methionine metabolism and alcoholic liver disease.
    Clinical chemistry and laboratory medicine, 2013, Mar-01, Volume: 51, Issue:3

    Topics: Epigenesis, Genetic; Ethanol; Folic Acid; Gene Expression Regulation; Humans; Kidney; Liver; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine; Vitamin B Complex; Vitamin B Deficiency

2013
CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment.
    Drug metabolism and drug interactions, 2012, Volume: 27, Issue:3

    Topics: Animals; Cytochrome P-450 CYP2E1; Disease Models, Animal; Ethanol; Humans; Liver Diseases; Liver Diseases, Alcoholic; Mice; Mice, Knockout; Obesity; Oxidative Stress; S-Adenosylmethionine

2012
Methionine metabolic pathway in alcoholic liver injury.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:1

    Topics: Aminobutyrates; Betaine; Biomarkers; Cystathionine; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Metabolic Networks and Pathways; Methionine; S-Adenosylmethionine

2013
Role of abnormal methionine metabolism in alcoholic liver injury.
    Alcohol (Fayetteville, N.Y.), 2002, Volume: 27, Issue:3

    Topics: Animals; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine

2002
S-Adenosylmethionine revisited: its essential role in the regulation of liver function.
    Alcohol (Fayetteville, N.Y.), 2002, Volume: 27, Issue:3

    Topics: Animals; Humans; Liver; Liver Diseases, Alcoholic; S-Adenosylmethionine

2002
S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings.
    Alcohol (Fayetteville, N.Y.), 2002, Volume: 27, Issue:3

    Topics: Animals; Disease Models, Animal; Humans; Liver Diseases, Alcoholic; S-Adenosylmethionine

2002
S-Adenosylmethionine, cytokines, and alcoholic liver disease.
    Alcohol (Fayetteville, N.Y.), 2002, Volume: 27, Issue:3

    Topics: Animals; Cytokines; Humans; Liver Diseases, Alcoholic; S-Adenosylmethionine

2002
S-Adenosyl-L-methionine and mitochondrial reduced glutathione depletion in alcoholic liver disease.
    Alcohol (Fayetteville, N.Y.), 2002, Volume: 27, Issue:3

    Topics: Animals; Glutathione; Humans; Liver Diseases, Alcoholic; Mitochondria, Liver; S-Adenosylmethionine

2002
S-adenosyl-L-methionine: its role in the treatment of liver disorders.
    The American journal of clinical nutrition, 2002, Volume: 76, Issue:5

    Topics: Animals; Antioxidants; Humans; Liver Diseases; Liver Diseases, Alcoholic; Reactive Oxygen Species; S-Adenosylmethionine

2002
New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments.
    Current gastroenterology reports, 2004, Volume: 6, Issue:1

    Topics: Adrenal Cortex Hormones; Alcoholism; Antioxidants; Colchicine; Cytokines; Drug Therapy, Combination; Female; Humans; Lipid Peroxidation; Liver Diseases, Alcoholic; Liver Function Tests; Male; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; S-Adenosylmethionine; Severity of Illness Index; Treatment Outcome

2004
Nutrition and alcoholic liver disease.
    Seminars in liver disease, 2004, Volume: 24, Issue:3

    Topics: Dietary Supplements; Enteral Nutrition; Humans; Liver Diseases, Alcoholic; Malnutrition; Parenteral Nutrition; Phosphatidylcholines; Prognosis; S-Adenosylmethionine

2004
Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.
    Alcohol (Fayetteville, N.Y.), 2005, Volume: 35, Issue:3

    Topics: Animals; Cell Death; Central Nervous System Depressants; Ethanol; Female; Hepatocytes; Humans; Isoenzymes; Liver; Liver Diseases, Alcoholic; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine

2005
Pathogenesis and treatment of alcoholic liver disease: progress over the last 50 years.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 2005, Volume: 50

    Topics: Animals; Antioxidants; History, 20th Century; History, 21st Century; Humans; Liver Diseases, Alcoholic; Phosphatidylcholines; S-Adenosylmethionine; Silymarin

2005
S-adenosyl-L-methionine for alcoholic liver diseases.
    The Cochrane database of systematic reviews, 2006, Apr-19, Issue:2

    Topics: Humans; Liver Diseases, Alcoholic; Randomized Controlled Trials as Topic; S-Adenosylmethionine

2006
Interactions of cytokines, S-Adenosylmethionine, and S-Adenosylhomocysteine in alcohol-induced liver disease and immune suppression.
    Journal of gastroenterology and hepatology, 2006, Volume: 21 Suppl 3

    Topics: Animals; Cytokines; Liver Diseases, Alcoholic; S-Adenosylhomocysteine; S-Adenosylmethionine

2006
Methionine adenosyltransferase and S-adenosylmethionine in alcoholic liver disease.
    Journal of gastroenterology and hepatology, 2006, Volume: 21 Suppl 3

    Topics: Animals; Apoptosis; Hepatocytes; Liver Diseases, Alcoholic; Methionine Adenosyltransferase; Mice; Mice, Knockout; S-Adenosylmethionine

2006
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:1

    Topics: Animals; Betaine; Disease Models, Animal; Folic Acid; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine

2007
The role of nutritional therapy in alcoholic liver disease.
    Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 2006, Volume: 29, Issue:4

    Topics: Dietary Fats; Humans; Liver Diseases, Alcoholic; Malnutrition; Phytotherapy; S-Adenosylmethionine; Silybum marianum

2006
[Latent alcoholic hepatopathy: diagnostic criteria, prognostic evaluation and therapeutic guidelines].
    La Clinica terapeutica, 1980, Mar-15, Volume: 92, Issue:5

    Topics: Catechin; Humans; Leucovorin; Lipotropic Agents; Liver Diseases, Alcoholic; Prognosis; Pyrazoles; S-Adenosylmethionine; Silymarin; Sulfhydryl Compounds; Vitamins

1980
Herman Award Lecture, 1993: a personal perspective on alcohol, nutrition, and the liver.
    The American journal of clinical nutrition, 1993, Volume: 58, Issue:3

    Topics: Alcoholic Intoxication; Awards and Prizes; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Nutrition Disorders; Nutritional Physiological Phenomena; Phosphatidylcholines; S-Adenosylmethionine; Societies, Medical

1993
ALCOHOL: its metabolism and interaction with nutrients.
    Annual review of nutrition, 2000, Volume: 20

    Topics: Alcohol Dehydrogenase; Animals; Antioxidants; Avitaminosis; Cytochrome P-450 CYP2E1 Inhibitors; Diet; Diet Therapy; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Nutritional Status; Oxidative Stress; S-Adenosylmethionine

2000
How is the liver primed or sensitized for alcoholic liver disease?
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:5 Suppl IS

    Topics: Animals; Bezafibrate; Endotoxins; Gene Expression; Hepatocytes; Humans; Hypolipidemic Agents; Iron; Kupffer Cells; Liver; Liver Diseases, Alcoholic; Mitochondria, Liver; Peroxisome Proliferators; S-Adenosylmethionine; Superoxides; Tretinoin; Tumor Necrosis Factor-alpha

2001
S-adenosyl-L-methionine for alcoholic liver diseases.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Humans; Liver Diseases, Alcoholic; Randomized Controlled Trials as Topic; S-Adenosylmethionine

2001

Trials

4 trial(s) available for s-adenosylmethionine and Alcoholic Liver Diseases

ArticleYear
Alcoholic liver disease patients treated with S-adenosyl-L-methionine: an in-depth look at liver morphologic data comparing pre and post treatment liver biopsies.
    Experimental and molecular pathology, 2013, Volume: 95, Issue:2

    Topics: Actins; Biopsy; Humans; Liver Diseases, Alcoholic; Muscle, Smooth; S-Adenosylmethionine

2013
S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial.
    Alcoholism, clinical and experimental research, 2011, Volume: 35, Issue:11

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Biopsy; Double-Blind Method; Female; Humans; Liver; Liver Diseases, Alcoholic; Male; Methionine; Middle Aged; Retrospective Studies; S-Adenosylmethionine; Treatment Outcome

2011
[Parenteral S-adenosylmethionine compared to placebos in the treatment of alcoholic liver diseases].
    Anales de medicina interna (Madrid, Spain : 1984), 1996, Volume: 13, Issue:1

    Topics: Adult; Double-Blind Method; Female; Humans; Injections, Intravenous; Liver Diseases, Alcoholic; Male; Middle Aged; Placebos; Prospective Studies; S-Adenosylmethionine; Time Factors

1996
Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:4

    Topics: Adult; Female; Glutathione; Humans; Liver; Liver Diseases; Liver Diseases, Alcoholic; Male; Middle Aged; S-Adenosylmethionine; Tablets

1989

Other Studies

22 other study(ies) available for s-adenosylmethionine and Alcoholic Liver Diseases

ArticleYear
Open-label study of ademetionine for the treatment of intrahepatic cholestasis associated with alcoholic liver disease.
    Minerva gastroenterologica e dietologica, 2018, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Aged; Cholestasis, Intrahepatic; Female; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Prospective Studies; S-Adenosylmethionine; Young Adult

2018
The role of adenosyl-methionine in alcoholic liver disease and intrahepatic cholestasis.
    Minerva gastroenterologica e dietologica, 2018, Volume: 64, Issue:3

    Topics: Animals; Cholestasis, Intrahepatic; Humans; Liver Diseases, Alcoholic; S-Adenosylmethionine

2018
[Correction of metabolic disorders during treatment of alcohol-induced liver injuries in patients with acute alcoholic intoxication].
    Klinicheskaia meditsina, 2013, Volume: 91, Issue:2

    Topics: Acute Disease; Adult; Alcoholic Intoxication; Comorbidity; Female; Humans; Liver Diseases, Alcoholic; Male; Metabolic Diseases; Middle Aged; S-Adenosylmethionine; Succinates

2013
[Hepatoprotectors in treatment of alcoholic liver disease].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2013, Issue:12

    Topics: Animals; Biological Products; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Phosphatidylcholines; Rats; Rats, Wistar; S-Adenosylmethionine; Treatment Outcome

2013
[Clinical efficacy of ademetionine "Heptor" in the therapy of alcohol-dependent liver disease].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2008, Issue:2

    Topics: Adult; Body Mass Index; Drug Administration Schedule; Female; Humans; Liver Diseases, Alcoholic; Liver Function Tests; Male; Middle Aged; Protective Agents; S-Adenosylmethionine; Treatment Outcome

2008
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:1

    Topics: Aldehyde Dehydrogenase; Animals; Betaine; Catalase; Central Nervous System Depressants; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dietary Fats; Dietary Supplements; Enzyme Induction; Ethanol; Glutathione; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Peroxisomes; S-Adenosylmethionine

2010
Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:5

    Topics: Animals; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Ethanol; Liver Diseases, Alcoholic; Male; Mitochondria, Liver; Mitochondrial Proteins; Oxygen Consumption; Proteome; Proteomics; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcription, Genetic

2010
SAMe prevents the up regulation of toll-like receptor signaling in Mallory-Denk body forming hepatocytes.
    Experimental and molecular pathology, 2010, Volume: 88, Issue:3

    Topics: Animals; Base Sequence; Dihydropyridines; Disease Models, Animal; DNA Primers; Hepatocytes; Humans; Inclusion Bodies; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C3H; Myeloid Differentiation Factor 88; S-Adenosylmethionine; Signal Transduction; TNF Receptor-Associated Factor 6; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors; Up-Regulation

2010
SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model.
    Experimental and molecular pathology, 2010, Volume: 88, Issue:3

    Topics: Animals; Base Sequence; Cysteine Endopeptidases; Dihydropyridines; Disease Models, Animal; DNA Primers; Gene Expression; Inclusion Bodies; Keratins; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C3H; Multienzyme Complexes; Proteasome Endopeptidase Complex; S-Adenosylmethionine; Ubiquitin; Ubiquitins

2010
The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine.
    Experimental and molecular pathology, 2010, Volume: 88, Issue:3

    Topics: Animal Nutritional Physiological Phenomena; Animals; Disease Models, Animal; Ethanol; Gene Expression; Histones; Liver; Liver Diseases, Alcoholic; Male; Methylation; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; S-Adenosylmethionine

2010
S-adenosylmethionine prevents the up regulation of Toll-like receptor (TLR) signaling caused by chronic ethanol feeding in rats.
    Experimental and molecular pathology, 2011, Volume: 90, Issue:3

    Topics: Animals; Biomarkers; Blotting, Western; Ethanol; Gene Expression Profiling; Liver Diseases, Alcoholic; Male; Oligonucleotide Array Sequence Analysis; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Toll-Like Receptors; Up-Regulation

2011
[Peculiarities of pharmacological correction of acute toxic hepatopathies in patients with severe forms of acute alcohol intoxication].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:1

    Topics: Alcoholic Intoxication; Humans; Liver Diseases, Alcoholic; Protective Agents; S-Adenosylmethionine; Succinates

2012
[Comparative evaluation of clinical efficacy of drugs remaxol and ademetionine in patients with acute ethanol poisoning complicated by the toxic damage of the liver].
    Georgian medical news, 2012, Issue:205

    Topics: Adult; Ethanol; Female; Humans; Liver; Liver Diseases, Alcoholic; Male; Poisoning; S-Adenosylmethionine; Succinates; Treatment Outcome

2012
[Characteristics of the pharmacological treatment of toxic liver damage in patients with an alcohol abused syndrome and an acute severe ethanol poison].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:1

    Topics: Adult; Alcoholism; Ethanol; Female; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; S-Adenosylmethionine; Succinates; Young Adult

2012
SAMe treatment prevents the ethanol-induced epigenetic alterations of genes in the Toll-like receptor pathway.
    Experimental and molecular pathology, 2013, Volume: 94, Issue:1

    Topics: Animals; DNA Methylation; Ethanol; Glucose; Liver; Liver Diseases, Alcoholic; Male; Rats; Rats, Wistar; S-Adenosylmethionine; Signal Transduction; Toll-Like Receptors

2013
Role of S-adenosyl-L-methionine in the treatment of alcoholic liver disease: introduction and summary of the symposium.
    Alcohol (Fayetteville, N.Y.), 2002, Volume: 27, Issue:3

    Topics: Animals; Antioxidants; Humans; Liver Diseases, Alcoholic; Oxidative Stress; S-Adenosylmethionine

2002
[Pathogenetic therapy of alcoholic liver disease].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:5

    Topics: Humans; Liver Diseases, Alcoholic; S-Adenosylmethionine

2002
RXRalpha-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity.
    Experimental and molecular pathology, 2003, Volume: 75, Issue:3

    Topics: Animals; Blotting, Northern; Cytochrome P-450 Enzyme System; Disease Susceptibility; Ethanol; Glutathione; Liver; Liver Diseases, Alcoholic; Mice; Mice, Transgenic; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; S-Adenosylmethionine; Transcription Factors

2003
S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 291, Issue:5

    Topics: Animals; Blotting, Western; Cytochrome P-450 CYP2E1; DNA, Mitochondrial; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Mitochondria, Liver; Molecular Chaperones; Nitric Oxide Synthase Type II; Oxidative Phosphorylation; Prohibitins; Rats; Rats, Sprague-Dawley; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine

2006
S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet.
    Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:11

    Topics: Animals; Body Weight; Disease Models, Animal; Ethanol; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Linear Models; Liver; Liver Diseases, Alcoholic; Male; Methionine; Necrosis; Oxidative Stress; S-Adenosylmethionine; Swine; Swine, Miniature

2007
Effect of S-adenosyl-L-methionine on ethanol cholestasis and hepatotoxicity in isolated perfused rat liver.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:7

    Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Ethanol; Glutathione; Injections, Intramuscular; L-Lactate Dehydrogenase; Liver; Liver Diseases, Alcoholic; Male; Malondialdehyde; Oxygen Consumption; Perfusion; Rats; Rats, Wistar; S-Adenosylmethionine

1995
Effect of nifedipine and S-adenosylmethionine in the liver of rats treated with CCl4 and ethanol for one month.
    Life sciences, 1992, Volume: 51, Issue:10

    Topics: Animals; Carbon Tetrachloride; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Lactates; Lactic Acid; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Male; Nifedipine; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1992