Compounds > s-adenosylmethionine
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s-adenosylmethionine and Aging

s-adenosylmethionine has been researched along with Aging in 88 studies

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-199026 (29.55)18.7374
1990's11 (12.50)18.2507
2000's16 (18.18)29.6817
2010's24 (27.27)24.3611
2020's11 (12.50)2.80

Authors

AuthorsStudies
Barretina, J; Biarnes, C; Borrás, C; Brugada, R; Daunis-I-Estadella, P; de la Fuente, M; Fernández-Bernal, A; Fernández-Real, JM; Galo-Licona, JD; Garre-Olmo, J; Jové, M; Martin-Garí, M; Mate, I; Mayneris-Perxachs, J; Mota-Martorell, N; Obis, È; Ortega-Bravo, M; Pamplona, R; Pedraza, S; Pineda, V; Portero-Otin, M; Pradas, I; Puig, J; Ramió-Torrentà, L; Ramos, R; Serena, J; Sol, J; Thió-Henestrosa, S; Vilanova, JC; Viña, J1
Davatzikos, C; Erus, G; Ferrucci, L; Mitchell, BA; Moaddel, R; Resnick, SM; Tian, Q1
Caldez, MJ; Choi, H; Coppola, V; Eisenhaber, F; Goh, CMF; Gopinathan, L; Jones, OS; Kaldis, P; Kanagasundaram, Y; Kien, YL; Kurochkin, IV; Low, KN; Maurer-Stroh, S; Niska-Blakie, J; Ong, CB; Pfeiffenberger, E; Tessarollo, L1
Bos, P; Keijer, J; Kleemann, R; Kuda, O; Nieuwenhuizen, AG; Paluchová, V; van den Hoek, AM; van der Hoek, MD; van der Leij, FR; Veeger, NJGM; Verschuren, L1
Chan, AW; Ching, J; Kovalik, JP; Matchar, DB; Ng, TKS1
Chew, H; Ching, J; Chow, VJ; Ewe, SH; Gao, F; Keng, BM; Koh, AS; Koh, WP; Kovalik, JP; Lee, LS; Leng, S; Tan, HC; Tan, RS; Tan, TY; Teo, LL; Zhao, X; Zhong, L1
Austad, SN; Bhattacharya, A; Chen, HI; Chen, Y; Fischer, KE; Gaczynska, M; Li, ME; Liang, H; Musi, N; Osmulski, P; Shoelson, SE; Valentine, JM; Van Remmen, H; Walsh, ME; Zhang, N; Zhang, Y; Zhou, Y1
Apte, U; Bensard, CL; Cox, J; Donato, AJ; Geoghegan, G; Huck, I; Jiang, L; Kershaw, EE; Lee, S; Longo, N; Maschek, JA; Miao, R; Pasquali, M; Rutter, J; Schreiber, R; Simcox, J; Villanueva, CJ; Zechner, R1
Ching, J; Chua, SJ; Fridianto, KT; Gao, F; Huang, FQ; Keng, BM; Koh, AS; Koh, WP; Kovalik, JP; Leng, S; Liu, J; Tan, RS; Wong, JI; Yuan, JM; Zhong, L1
Cianfarani, MA; Copetti, M; Di Cola, G; Federici, M; Luzi, A; Pecchioli, C; Pellegrini, F; Porzio, O; Rizza, S; Rossi, C; Urbani, A; Zucchelli, M1
Elliott, CT; Graham, SF; Green, BD; Hölscher, C; Kehoe, PG; McClean, PL; McGuinness, B; Nasaruddin, MB; Pan, X; Passmore, AP1
Bain, JR; Cohen, HJ; Huffman, KM; Kraus, VB; Kraus, WE; Morey, MC; Newgard, CB; Pieper, CF; Ravussin, E; Redman, LM; Stevens, RD; Thompson, DK1
Caltagirone, C; Ciavardelli, D; Consalvo, A; Di Ilio, C; Frazzini, V; Piras, F; Rossi, C; Sensi, SL; Spalletta, G; Zucchelli, M1
Consitt, LA; Houmard, JA; Koves, TR; Muoio, DM; Nakazawa, M; Newton, CA1
Hegardt, FG; Ilkayeva, O; Koves, TR; Lum, H; Lust, RM; Muoio, DM; Noland, RC; Seiler, SE; Stevens, RD1
Bain, JR; Huffman, KM; Kraus, VB; Kraus, WE; Landerman, LR; Muehlbauer, MJ; Newgard, CB; Pieper, CF; Ravussin, E; Redman, LM; Stevens, RD; Wenner, BR1
Adamski, J; Blum, H; Göke, B; Krebs, S; Prehn, C; Renner, S; Römisch-Margl, W; Roscher, AA; Suhre, K; Wolf, E1
Bain, JR; Brinton, LA; Falk, RT; Garcia-Closas, M; Gaudet, MM; Gunter, MJ; Lissowska, J; Newgard, CB; Peplonska, B; Pfeiffer, RM; Potischman, N; Sherman, ME; Stevens, RD1
Harashima, H; Hayashi, M; Horiuchi, M; Kamido, H; Kudo, T; Kuwajima, M; Lu, K; Ono, A; Ozaki, K; Saheki, T; Sei, M; Shima, K1
Hayashi, Y; Hino, S; Kang, W; Kashio, S; Kobayashi, S; Miura, M; Miyado, K; Murotomi, K; Nakao, M; Namihira, M1
Anand, RS; Ganesan, D; Jayavelu, T; Rajasekaran, S; Selvam, S1
Lin, WQ; Ngian, ZK; Ong, CT1
Osborne, DM; Vander Velden, JW1
Chen, S; Fang, AP; He, TT; Hou, MJ; Long, JA; Lu, XT; Luo, Y; Tan, XY; Tang, ZH; Yishake, D; Zhong, RH; Zhu, HL1
Amaral, AU; Cecatto, C; Leipnitz, G; Ribeiro, RT; Wajner, M; Wyse, AT; Zanatta, Â1
Bhat, JA; Dar, NJ; Gupta, AP; Hamid, A; Kaur, J; Najar, RA; Rahat, B; Wani, NA1
Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R1
Benda, A; Kollárová, J; Kostrouchová, M1
Miura, M; Obata, F1
Dammann, P; Dziegelewska, M; Groth, M; Hildebrandt, T; Holtze, S; Huse, K; Menzel, U; Morhart, M; Platzer, M; Sahm, A; Sponholz, C; Szafranski, K; Vole, C; Wachter, U1
Dramard, V; Halsberghe, C; Hofmans, J; Kern, L; Mombiela, DV; Rème, CA1
Blom, HJ; Hooijmans, CR; Kiliaan, AJ; Oppenraaij-Emmerzaal, D; Ritskes-Hoitinga, M1
Fenech, M1
Eckert, R; Herrmann, W; Kasoha, M; Kirsch, SH; Obeid, R1
Choi, SW; Friso, S; Park, LK1
Casson, RI; Dodds, L; Ho, V; King, WD; Massey, TE; Perkins, SL1
David, LL; Davies, MJ; Friedrich, MG; Hooi, MY; Jamie, JF; Lyons, B; Mizdrak, J; Truscott, RJ; Wilmarth, PA1
Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G1
Blom, HJ; Farkas, M; Jessen, F; Linnebank, M; Popp, J; Semmler, A; Smith, DE; Smulders, YM1
Eto, K; Kimura, H1
Brown-Borg, HM; Uthus, EO1
Clarke, S; Vitali, R1
Ariznavarreta, C; Castillo, C; Fossati, M; Salazar, V; Tresguerres, JA; Vara, E1
Cavallaro, RA; D'Anselmi, F; Fuso, A; Scarpa, S1
Cavallaro, RA; D'Anselmi, F; Fuso, A; Scarpa, S; Seminara, L1
Cho, YM; Choi, SW; Friso, S; Jin, CJ; Kim, MS; Lee, HK; Lee, KU; Pak, YK; Park, HK; Park, KS1
Andrews, LG; Berletch, JB; Phipps, SM; Tollefsbol, TO; Walthall, SL1
Allen, RH; Barbosa, PR; Carvalho, FR; Guerra-Shinohara, EM; Hirata, MH; Hirata, RD; Luchessi, AD; Stabler, SP; Trentin, R1
Chan, A; Graves, V; Rozen, R; Shea, TB; Tchantchou, F1
Algeri, S; Cimino, M; Curatola, G; Pezzoli, C; Stramentinoli, G; Vantini, G1
Ando, S; Kon, K; Ono, Y; Tanaka, Y1
Chabannes, B; Cronenberger, L; Gharib, A; Pacheco, H; Sarda, N1
Bone, AH; Taufek, HR1
Denisova, NA; Kelly, JF; Kowatch, MA; Roth, GS1
García-Cuevas, M; Pérez-Olleros, L; Ruiz-Roso, B; Varela-Moreiras, G1
Löfberg, C; Oreland, L; Trolin, CG; Trolin, G1
Clarke, S1
Endo, N; Sano, A; Takitani, S1
Ben-Baruch, G; Egozi, Y; Haklai, R; Kloog, Y; Marciano, D; Paz, A1
Choi, SW; Ghandour, H; Lin, BF; Mason, JB; Selhub, J1
Golubev, AG; Khavinson, VKh1
Arrigoni, E; Benzi, G; Strada, P; Villa, RF1
Cornatzer, WE; Duerre, JA; Hoffman, DR1
Culver, MG; Weirich, GF1
Algeri, S; Catto, E; Gualano, M; Stramentinoli, G1
Blackwell, LA; Grover, TA; Middaugh, LD; Zemp, JW1
Kudriashova, IB; Vaniushin, BF1
Bertacco, S; Di Carlo, R; Muccioli, G; Scordamaglia, A1
Kanungo, MS; Saran, S1
Coltorti, M; Di Padova, C; Gentile, S; Le Grazie, C; Orlando, C; Persico, M1
Hyland, K; Surtees, R1
Gharib, A; Reynaud, D; Sarda, N1
Mills, GC1
Di Carlo, R; Muccioli, G1
Geller, AM; Jernigan, HM; Kotb, MY; Kredich, NM1
Kramer, CM; Sellinger, OZ1
Carnegie, PR; Jones, GM1
Axelrod, J; Coyle, JT; Saavedra, JM1
Chou, L; Johnson, TC; Mathews, RA1
Duerre, JA; Lee, CT1
Jacob, M; Judes, C1
Benditt, M; Kim, S; Paik, WK1
Kim, S; Paik, WK1
Wainwright, SD1
Simon, LN; Streeter, DG; Swiatek, KR1
Curri, SB1
Lombardini, JP; Russell, DH1

Reviews

7 review(s) available for s-adenosylmethionine and Aging

ArticleYear
Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2016, Volume: 71, Issue:11

    Topics: Aged; Aging; Amino Acids; Body Mass Index; Carnitine; Female; Humans; Male; Metabolomics; Obesity; Plasma

2016
Folate, DNA damage and the aging brain.
    Mechanisms of ageing and development, 2010, Volume: 131, Issue:4

    Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil

2010
Nutritional influences on epigenetics and age-related disease.
    The Proceedings of the Nutrition Society, 2012, Volume: 71, Issue:1

    Topics: Aging; Animals; Cardiovascular Diseases; Diet; DNA Methylation; Epigenesis, Genetic; Epigenomics; Humans; Micronutrients; Neoplasms; Neurodegenerative Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine

2012
Gene silencing through methylation: an epigenetic intervention on Alzheimer disease.
    Journal of Alzheimer's disease : JAD, 2006, Volume: 9, Issue:4

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Brain; DNA Methylation; Epigenesis, Genetic; Gene Silencing; Humans; S-Adenosylmethionine

2006
A method to study the expression of DNA methyltransferases in aging systems in vitro.
    Methods in molecular biology (Clifton, N.J.), 2007, Volume: 371

    Topics: Aging; Animals; Cell Culture Techniques; Cells, Cultured; Cellular Senescence; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation, Enzymologic; Genome; Humans; Models, Biological; Protein Processing, Post-Translational; Regulatory Elements, Transcriptional; S-Adenosylmethionine; Transcription, Genetic

2007
Protein methylation.
    Current opinion in cell biology, 1993, Volume: 5, Issue:6

    Topics: Aging; Amino Acid Sequence; Amino Acids; Animals; Eukaryotic Cells; Methylation; Molecular Sequence Data; Prokaryotic Cells; Protein Methyltransferases; Protein Processing, Post-Translational; Proteins; S-Adenosylmethionine

1993
Anti-aging products, Part I. Can supplements rewind our body clocks?
    Harvard women's health watch, 2001, Volume: 9, Issue:4

    Topics: Advertising; Aging; Antioxidants; Coenzymes; Dietary Supplements; Evidence-Based Medicine; Humans; Patient Education as Topic; S-Adenosylmethionine; Superoxide Dismutase; Thioctic Acid; Ubiquinone

2001

Trials

3 trial(s) available for s-adenosylmethionine and Aging

ArticleYear
Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:2

    Topics: Adiposity; Adult; Aging; Amino Acids; Body Composition; Caloric Restriction; Carnitine; Cross-Sectional Studies; Data Interpretation, Statistical; Exercise; Fatty Acids; Female; Humans; Insulin Resistance; Male; Metabolism; Middle Aged; Overweight; Principal Component Analysis; Sex Characteristics; Spectrum Analysis; Weight Loss

2011
Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: a double-blinded, placebo-controlled trial.
    Veterinary therapeutics : research in applied veterinary medicine, 2008,Summer, Volume: 9, Issue:2

    Topics: Aging; Animals; Cognition Disorders; Dog Diseases; Dogs; Female; Locomotion; Male; S-Adenosylmethionine; Treatment Outcome

2008
Concentrations of unmetabolized folic acid and primary folate forms in plasma after folic acid treatment in older adults.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex

2011

Other Studies

78 other study(ies) available for s-adenosylmethionine and Aging

ArticleYear
Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome.
    Aging cell, 2023, Volume: 22, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids, Aromatic; Biomarkers; Female; Humans; Male; Metabolome; Metabolomics; Middle Aged; Young Adult

2023
Sex differences in plasma lipid profiles of accelerated brain aging.
    Neurobiology of aging, 2023, Volume: 129

    Topics: Aging; Atrophy; Brain; Ceramides; Female; Humans; Male; Sex Characteristics; Triglycerides

2023
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
    Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:17

    Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplements; Feces; Gastrointestinal Microbiome; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Metabolic Syndrome; Metabolome; Mice; Mice, Knockout; Obesity; Tryptophan

2020
Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Carnitine; Cross-Sectional Studies; Female; Frail Elderly; Frailty; Hand Strength; Humans; Male; Muscles; Physical Fitness; Sex Factors; Walking

2020
Novel metabolomics markers are associated with pre-clinical decline in hand grip strength in community-dwelling older adults.
    Mechanisms of ageing and development, 2021, Volume: 193

    Topics: Aged; Aging; Asymptomatic Diseases; Biomarkers; Carnitine; Energy Metabolism; Fatty Acids; Female; Frailty; Geriatric Assessment; Hand Strength; Humans; Independent Living; Longitudinal Studies; Male; Metabolomics; Mitochondria, Muscle; Prognosis; Sarcopenia

2021
Exacerbation of cardiovascular ageing by diabetes mellitus and its associations with acyl-carnitines.
    Aging, 2021, 06-04, Volume: 13, Issue:11

    Topics: Aged; Aging; Cardiovascular System; Carnitine; Diabetes Mellitus; Female; Humans; Male; Middle Aged

2021
Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health.
    Aging cell, 2017, Volume: 16, Issue:4

    Topics: Aging; Animals; Blood Glucose; Carnitine; Cell Line; Ceramides; Female; Gene Expression Regulation; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Atrophy; Myoblasts; Myostatin; NF-kappa B; NF-KappaB Inhibitor alpha; Sarcopenia

2017
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.
    Cell metabolism, 2017, Sep-05, Volume: 26, Issue:3

    Topics: Adipose Tissue, Brown; Aging; Animals; Body Temperature; Carnitine; Carnitine O-Palmitoyltransferase; Citric Acid Cycle; Cold Temperature; Fatty Acids; Gene Expression Regulation; Gene Knockdown Techniques; Hepatocyte Nuclear Factor 4; Lipids; Lipolysis; Liver; Mice; Phenotype; Thermogenesis; Time Factors

2017
Metabolomic profile of arterial stiffness in aged adults.
    Diabetes & vascular disease research, 2018, Volume: 15, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Arterial Pressure; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Manometry; Metabolomics; Middle Aged; Predictive Value of Tests; Prospective Studies; Pulse Wave Analysis; Risk Factors; Vascular Stiffness

2018
Metabolomics signature improves the prediction of cardiovascular events in elderly subjects.
    Atherosclerosis, 2014, Volume: 232, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Cardiovascular Diseases; Carnitine; Cellular Senescence; Female; Follow-Up Studies; Humans; Male; Metabolic Networks and Pathways; Metabolomics; Myocardial Infarction; Principal Component Analysis; Proportional Hazards Models; Reproducibility of Results; Stroke

2014
Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome.
    Neurobiology of aging, 2016, Volume: 38

    Topics: Aging; Alzheimer Disease; Amino Acids, Branched-Chain; Amino Acids, Essential; Animals; Biogenic Polyamines; Brain; Carnitine; Disease Models, Animal; Male; Metabolome; Mice, Transgenic; Phospholipids; Serotonin

2016
Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimer's disease subjects.
    Neurobiology of aging, 2016, Volume: 43

    Topics: Aged; Aging; Alzheimer Disease; Carnitine; Cognition; Cognitive Dysfunction; Cohort Studies; Female; Gray Matter; Humans; Hydroxybutyrates; Ketone Bodies; Male

2016
Plasma acylcarnitines during insulin stimulation in humans are reflective of age-related metabolic dysfunction.
    Biochemical and biophysical research communications, 2016, Oct-28, Volume: 479, Issue:4

    Topics: Acetyl-CoA Carboxylase; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Carnitine; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Muscle, Skeletal; Oxidation-Reduction; Phosphorylation; Young Adult

2016
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control.
    The Journal of biological chemistry, 2009, Aug-21, Volume: 284, Issue:34

    Topics: Aging; Animals; Biological Transport; Blotting, Western; Carnitine; Carnitine O-Acetyltransferase; Cells, Cultured; Dietary Fats; gamma-Butyrobetaine Dioxygenase; Glucose Intolerance; Glucose Tolerance Test; Humans; Lipid Metabolism; Male; Mitochondria, Muscle; Mixed Function Oxygenases; Overnutrition; Oxidative Phosphorylation; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Vitamin B Complex

2009
Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced β-cell mass.
    Diabetes, 2012, Volume: 61, Issue:8

    Topics: Aging; Amino Acids; Animals; Animals, Genetically Modified; Biomarkers; Carnitine; Diglycerides; Disease Progression; Glucose Tolerance Test; Incretins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lipids; Lysophosphatidylcholines; Phospholipid Ethers; Prediabetic State; Receptors, Gastrointestinal Hormone; Sphingomyelins; Swine; Transcriptome

2012
Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:9

    Topics: Adult; Aged; Aging; Algorithms; Amino Acids; Body Mass Index; Body Weight; Carnitine; Case-Control Studies; Data Interpretation, Statistical; Endometrial Neoplasms; Fatty Acids; Female; Humans; Male; Middle Aged; Poland; Population; Quality Control

2012
Cardiomegaly in the juvenile visceral steatosis (JVS) mouse is reduced with acute elevation of heart short-chain acyl-carnitine level after L-carnitine injection.
    FEBS letters, 1999, Jan-29, Volume: 443, Issue:3

    Topics: Aging; Animals; Body Weight; Cardiomegaly; Carnitine; Disease Models, Animal; Half-Life; Injections, Intraperitoneal; Lipid Metabolism; Mice; Mice, Inbred Strains; Myocardium; Organ Size; Time Factors

1999
Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis.
    Scientific reports, 2022, 04-04, Volume: 12, Issue:1

    Topics: Aging; Animals; Drosophila; Methionine Adenosyltransferase; Mice; Oogenesis; S-Adenosylmethionine

2022
Distinct utilization of biotin in and between adipose and brain during aging is associated with a lipogenic shift in Wistar rat brain.
    Nutrition research (New York, N.Y.), 2020, Volume: 79

    Topics: Acetyl-CoA Carboxylase; Adipocytes; Adipose Tissue; Aging; Animals; Astrocytes; Biotin; Biotinylation; Brain; Cells, Cultured; Endoplasmic Reticulum Stress; Lipid Metabolism; Lipogenesis; Male; Rats; Rats, Wistar; S-Adenosylmethionine

2020
NELF-A controls Drosophila healthspan by regulating heat-shock protein-mediated cellular protection and heterochromatin maintenance.
    Aging cell, 2021, Volume: 20, Issue:5

    Topics: Aging; Animals; Cell Line; DNA Damage; Drosophila; Drosophila Proteins; Gene Expression Regulation; Heat-Shock Proteins; Heterochromatin; Histones; Humans; Locomotion; Longevity; Neurons; Oxidative Stress; Protein Aggregates; Reactive Oxygen Species; Retroelements; RNA-Binding Proteins; S-Adenosylmethionine; Transcription Factors; Transcription, Genetic

2021
Obesity Prevents S-Adenosylmethionine-Mediated Improvements in Age-Related Peripheral and Hippocampal Outcomes.
    Nutrients, 2021, Apr-06, Volume: 13, Issue:4

    Topics: Aging; Animals; Anxiety; Blood Glucose; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Glutathione; Hippocampus; Humans; Inflammation; Insulin Resistance; Liver; Male; Mice; Mice, Obese; Obesity; S-Adenosylmethionine; Transforming Growth Factor beta1

2021
Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:15

    Topics: Aging; Animals; Betaine; Gene Expression Regulation; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Lysosomes; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Methyltransferases; Mice, Inbred C57BL; Muscle, Skeletal; Protein Biosynthesis; S-Adenosylmethionine; Signal Transduction

2021
S-Adenosylmethionine Promotes Oxidative Stress and Decreases Na
    Molecular neurobiology, 2018, Volume: 55, Issue:7

    Topics: Adenosylhomocysteinase; Aging; Animals; Antioxidants; Cerebral Cortex; Homeostasis; Lipid Peroxidation; Malondialdehyde; Membrane Fluidity; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats, Wistar; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes

2018
Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation.
    The Journal of nutritional biochemistry, 2018, Volume: 53

    Topics: Aging; Animals; Cyclins; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Epigenesis, Genetic; Folic Acid; Gene Expression Regulation; Genes, myc; Genes, Tumor Suppressor; JNK Mitogen-Activated Protein Kinases; Liver; Male; Rats, Wistar; S-Adenosylmethionine; Tetrahydrofolates

2018
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
    Molecular neurobiology, 2019, Volume: 56, Issue:6

    Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission

2019
ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
    Folia biologica, 2018, Volume: 64, Issue:2

    Topics: Aging; AlkB Enzymes; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dioxygenases; Down-Regulation; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Ketoglutaric Acids; Larva; Longevity; Lysosomes; Methyltransferases; Operon; Promoter Regions, Genetic; RNA Interference; S-Adenosylmethionine

2018
Enhancing S-adenosyl-methionine catabolism extends Drosophila lifespan.
    Nature communications, 2015, Sep-18, Volume: 6

    Topics: Aging; Animals; Animals, Genetically Modified; Blotting, Western; Caloric Restriction; Chromatography, Liquid; Drosophila melanogaster; Drosophila Proteins; Gene Knockdown Techniques; Glycine N-Methyltransferase; Insulin; Longevity; Methionine Adenosyltransferase; Real-Time Polymerase Chain Reaction; S-Adenosylmethionine; Sarcosine; Tandem Mass Spectrometry

2015
Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat.
    Redox biology, 2016, Volume: 8

    Topics: Aging; Animals; Cystathionine beta-Synthase; Diet; Hydrogen Sulfide; Liver; Longevity; Methionine; Mole Rats; Rats; S-Adenosylmethionine

2016
S-adenosylmethionine and S-adenosylhomocysteine levels in the aging brain of APP/PS1 Alzheimer mice.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2009, Volume: 30, Issue:5

    Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Chromatography, Liquid; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Presenilin-1; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry

2009
Relationships among biomarkers of one-carbon metabolism.
    Molecular biology reports, 2012, Volume: 39, Issue:7

    Topics: Adult; Aging; Biomarkers; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Vitamin B 12; Young Adult

2012
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
    Experimental eye research, 2012, Volume: 99

    Topics: Adolescent; Adult; Aged; Aging; beta-Crystallin A Chain; Chromatography, High Pressure Liquid; Cysteine; Histidine; Humans; Lens, Crystalline; Mass Spectrometry; Methylation; Middle Aged; Protein Methyltransferases; Protein Processing, Post-Translational; Proteomics; S-Adenosylmethionine; Tissue Donors; Young Adult

2012
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
    European journal of nutrition, 2013, Volume: 52, Issue:3

    Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine

2013
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid.
    Clinical chemistry and laboratory medicine, 2012, Mar-24, Volume: 50, Issue:9

    Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry; Vitamin B 12

2012
The production of hydrogen sulfide is regulated by testosterone and S-adenosyl-L-methionine in mouse brain.
    Journal of neurochemistry, 2002, Volume: 83, Issue:1

    Topics: Age Factors; Aging; Animals; Brain; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Cysteine; Female; Hydrogen Sulfide; Male; Mice; Mice, Inbred BALB C; S-Adenosylmethionine; Sex Factors; Testosterone

2002
Altered methionine metabolism in long living Ames dwarf mice.
    Experimental gerontology, 2003, Volume: 38, Issue:5

    Topics: Aging; Animals; Brain; Cystathionine beta-Synthase; DNA Methylation; Glycine N-Methyltransferase; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine

2003
Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase.
    Behavioural brain research, 2004, Aug-12, Volume: 153, Issue:1

    Topics: Age Factors; Aging; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Diet, Reducing; Exploratory Behavior; Genotype; Homocysteine; Hyperkinesis; Mice; Mice, Knockout; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rotarod Performance Test; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereotyped Behavior; Survival Rate; Time Factors

2004
Effect of S-adenosylmethionine on age-induced hepatocyte damage in old Wistar rats.
    Biogerontology, 2005, Volume: 6, Issue:5

    Topics: Aging; Animals; Carbon Monoxide; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glutathione; Hepatocytes; Male; Methionine Adenosyltransferase; Methyltransferases; Nitric Oxide; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; S-Adenosylmethionine

2005
The effect of S-adenosylmethionine on CNS gene expression studied by cDNA microarray analysis.
    Journal of Alzheimer's disease : JAD, 2006, Volume: 9, Issue:4

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Cell Line, Tumor; Chromatography, High Pressure Liquid; DNA Methylation; Gene Expression; Humans; Membrane Proteins; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Presenilin-1; RNA; S-Adenosylmethionine

2006
S-adenosyl-L-methionine increases skeletal muscle mitochondrial DNA density and whole body insulin sensitivity in OLETF rats.
    The Journal of nutrition, 2007, Volume: 137, Issue:2

    Topics: Aging; Animals; Diabetes Mellitus, Type 2; DNA; Feeding Behavior; Glucose; Insulin; Insulin Resistance; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Inbred OLETF; S-Adenosylmethionine; Weight Gain

2007
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
    Clinica chimica acta; international journal of clinical chemistry, 2008, Volume: 388, Issue:1-2

    Topics: Adult; Aging; Alleles; Anemia, Iron-Deficiency; Avitaminosis; Brazil; Female; Genotype; Homocysteine; Humans; Methylmalonic Acid; Nutritional Physiological Phenomena; Polymorphism, Genetic; Reproduction; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamins

2008
Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine.
    The journal of nutrition, health & aging, 2008, Volume: 12, Issue:4

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Acetylcholine; Aggression; Aging; Animals; Apolipoproteins E; Cognition; Folic Acid; Folic Acid Deficiency; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Random Allocation; S-Adenosylmethionine

2008
Age-related modification of dopaminergic and beta-Adrenergic receptor system: restoration to normal activity by modifying membrane fluidity with S-adenosylmethionine.
    Life sciences, 1984, May-21, Volume: 34, Issue:21

    Topics: Aging; Animals; Cell Membrane; Cerebral Cortex; Corpus Striatum; Dihydroalprenolol; Kinetics; Membrane Fluidity; Phospholipids; Rats; Receptors, Adrenergic, beta; Receptors, Dopamine; S-Adenosylmethionine; Spiperone

1984
Incorporation rate of GM1 ganglioside into mouse brain myelin: effect of aging and modification by hormones and other compounds.
    Advances in experimental medicine and biology, 1984, Volume: 174

    Topics: Aging; Animals; Brain; Ethinyl Estradiol; Female; G(M1) Ganglioside; Gangliosides; Globosides; Mice; Mice, Inbred C57BL; Myelin Sheath; Propylthiouracil; S-Adenosylmethionine; Thyroxine

1984
The regional concentrations of S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and adenosine in rat brain.
    Journal of neurochemistry, 1982, Volume: 38, Issue:3

    Topics: Adenosine; Aging; Animals; Brain; Brain Chemistry; Homocysteine; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tissue Distribution

1982
Influence of exogenous L-3,4,-dihydroxyphenylalanine (L-dopa) on the methionine and s-adenosylmethionine concentrations in the brain and other tissues [proceedings].
    Biochemical Society transactions, 1980, Volume: 8, Issue:1

    Topics: Aging; Animals; Brain; Iproniazid; Kidney; Levodopa; Liver; Methionine; Organ Specificity; Rats; S-Adenosylmethionine

1980
Partial restoration of impaired alpha 1-adrenergic responsiveness in parotid cells of aged rats by S-adenosylmethionine treatment.
    Molecular and cellular biochemistry, 1995, Jul-05, Volume: 148, Issue:1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aging; Animals; Fluorescence Polarization; Inositol 1,4,5-Trisphosphate; Male; Membrane Fluidity; Membrane Lipids; Methylation; Parotid Gland; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Viscosity

1995
Effects of ageing on folate metabolism in rats fed a long-term folate deficient diet.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1994, Volume: 64, Issue:4

    Topics: Aging; Animals; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine

1994
Brain ATP:L-methionine S-adenosyltransferase (MAT), S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH): regional distribution and age-related changes.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Humans; Kinetics; Male; Methionine Adenosyltransferase; Middle Aged; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet

1994
Fluorometric assay of rat brain N-methyltransferase with 4-methylnicotinamide.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:3

    Topics: Aging; Animals; Brain; Chromatography, High Pressure Liquid; Enzyme Stability; Female; Kinetics; Male; Methyltransferases; Niacinamide; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Spectrometry, Fluorescence

1993
Prenylated protein methyltransferase of rat cerebellum is developmentally co-expressed with its substrates.
    FEBS letters, 1993, Oct-18, Volume: 332, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Cerebellum; GTP-Binding Proteins; Methylation; Nerve Tissue Proteins; Protein Methyltransferases; Rats; S-Adenosylmethionine; Subcellular Fractions; Synaptosomes

1993
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
    The Journal of nutrition, 2002, Volume: 132, Issue:6

    Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine

2002
[Aging of the pineal gland].
    Advances in gerontology = Uspekhi gerontologii, 2002, Volume: 9

    Topics: Aging; Animals; Antioxidants; Female; Melatonin; Monoamine Oxidase Inhibitors; Oligopeptides; Pineal Gland; S-Adenosylmethionine

2002
Enzymatic activities in the senescent brain and interference with S-adenosyl-L-methionine.
    Experimental gerontology, 1979, Volume: 14, Issue:4

    Topics: Aging; Brain; Citrate (si)-Synthase; Electron Transport Complex IV; L-Lactate Dehydrogenase; Malate Dehydrogenase; S-Adenosylmethionine

1979
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions.
    Canadian journal of biochemistry, 1979, Volume: 57, Issue:1

    Topics: Aging; Animals; Female; Homocysteine; Liver; Methylation; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine

1979
S-Adenosylmethionine:Juvenile hormone acid methyltransferase in male accessory reproductive glands of Hyalophora cecropia (L.).
    Archives of biochemistry and biophysics, 1979, Volume: 198, Issue:1

    Topics: Aging; Animals; Genitalia, Male; Juvenile Hormones; Lepidoptera; Male; Methyltransferases; Moths; S-Adenosylmethionine; Subcellular Fractions

1979
Tissue levels of S-adenosylmethionine in aging rats.
    Journal of gerontology, 1977, Volume: 32, Issue:4

    Topics: Adrenal Glands; Aging; Animals; Brain; Brain Chemistry; Catechol O-Methyltransferase; Liver; Lung; Male; Muscles; Rats; S-Adenosylmethionine

1977
Neurochemical and behavioral effects of diet related perinatal folic acid restriction.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain; Diet; Escape Reaction; Female; Folic Acid; Folic Acid Deficiency; Liver; Mice; Organ Size; Pregnancy; S-Adenosylmethionine; Stress, Physiological

1976
[In vitro methylation of nuclear DNA from various organs of a rat: Tissue and age differences in acceptor ability of DNA].
    Biokhimiia (Moscow, Russia), 1976, Volume: 41, Issue:6

    Topics: Aging; Animals; Brain; Cell Nucleus; Culture Media; DNA; DNA (Cytosine-5-)-Methyltransferases; In Vitro Techniques; Kidney; Liver; Lung; Methylation; Methyltransferases; Rats; S-Adenosylmethionine; Spleen; Tritium

1976
Effect of S-adenosyl-L-methionine on brain muscarinic receptors of aged rats.
    European journal of pharmacology, 1992, Nov-02, Volume: 227, Issue:3

    Topics: Aging; Animals; Brain Chemistry; Corpus Striatum; Hippocampus; In Vitro Techniques; Male; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; S-Adenosylmethionine; Tritium

1992
Methylation, acetylation and phosphorylation of the bases of DNA of young and old rats.
    Indian journal of biochemistry & biophysics, 1991, Volume: 28, Issue:2

    Topics: Acetyl Coenzyme A; Acetylation; Adenosine Triphosphate; Aging; Animals; Brain; Cell Nucleus; DNA; Female; Liver; Methylation; Phosphorylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine

1991
Age-associated decline of hepatic handling of cholephilic anions in humans is reverted by S-adenosylmethionine (SAMe).
    Scandinavian journal of clinical and laboratory investigation, 1990, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anions; Bilirubin; Humans; Kinetics; Liver; Male; Membrane Fluidity; Niacin; S-Adenosylmethionine

1990
Cerebrospinal fluid concentrations of S-adenosylmethionine, methionine, and 5-methyltetrahydrofolate in a reference population: cerebrospinal fluid S-adenosylmethionine declines with age in humans.
    Biochemical medicine and metabolic biology, 1990, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Methionine; S-Adenosylmethionine; Tetrahydrofolates

1990
S-adenosylmethionine, S-adenosylhomocysteine and adenosine system. Age-dependent availability in rat brain.
    Developmental pharmacology and therapeutics, 1989, Volume: 13, Issue:2-4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Homocysteine; In Vitro Techniques; Kinetics; Male; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine

1989
Isolation and identification of S-adenosylmethionine from human urine.
    Biochemical medicine and metabolic biology, 1989, Volume: 41, Issue:3

    Topics: Adult; Aging; Buffers; Child, Preschool; Chromatography, Ion Exchange; Female; Humans; Male; S-Adenosylmethionine; Spectrophotometry, Ultraviolet

1989
S-adenosyl-L-methionine restores prolactin receptors in the aged rabbit brain.
    European journal of pharmacology, 1989, Jul-18, Volume: 166, Issue:2

    Topics: Aging; Animals; Brain Chemistry; Hypothalamus; Iodine Radioisotopes; Liver; Male; Membranes; Rabbits; Receptors, Prolactin; S-Adenosylmethionine

1989
Methionine adenosyltransferase and S-adenosylmethionine in the developing rat lens.
    Experimental eye research, 1988, Volume: 47, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Lens, Crystalline; Methionine Adenosyltransferase; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Transferases

1988
The carboxylmethylation of membrane-bound proteins in the aging rat brain.
    Advances in experimental medicine and biology, 1988, Volume: 231

    Topics: Aging; Animals; Brain; Kinetics; Male; Membrane Proteins; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Synaptic Membranes

1988
Methylation of myelin basic protein by enzymes from rat brain.
    Journal of neurochemistry, 1974, Volume: 23, Issue:6

    Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration

1974
Developmental characteristics of phenylethanolamine and octopamine in the rat brain.
    Journal of neurochemistry, 1974, Volume: 23, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Chromatography, Thin Layer; Dopamine beta-Hydroxylase; Ethanolamines; Female; Fenclonine; Fetus; Gestational Age; Iproniazid; Monoamine Oxidase; Norepinephrine; Octopamine; Phenethylamines; Phenylethanolamine N-Methyltransferase; Pregnancy; Rats; S-Adenosylmethionine; Time Factors; Tritium; Tyrosine 3-Monooxygenase

1974
tRNA methyltransferase activity in neonatal and mature mammalian neural tissue.
    Journal of neurochemistry, 1974, Volume: 23, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Centrifugation, Density Gradient; Cytosol; Drug Stability; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mice; Niacinamide; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Subcellular Fractions; Temperature; Time Factors; tRNA Methyltransferases; Ultracentrifugation

1974
Changes in histone methylase activity of rat brain and liver with ageing.
    Nature, 1974, Sep-20, Volume: 251, Issue:5472

    Topics: Aging; Animals; Brain; Cell Nucleus; Histones; Liver; Methylation; Methyltransferases; Rats; S-Adenosylmethionine

1974
Compartmentation of the S-adenosylmethionne pool in developing chick embryo cerebral hemispheres, as demonstrated by a fingerprint study of 18 S ribosomal RNA.
    FEBS letters, 1972, Nov-01, Volume: 27, Issue:2

    Topics: Aging; Animals; Brain; Carbon Isotopes; Centrifugation, Density Gradient; Chick Embryo; Electrophoresis; In Vitro Techniques; RNA, Ribosomal; S-Adenosylmethionine; Time Factors

1972
Protein methylase 3 of rat kidney during the early development.
    FEBS letters, 1973, Sep-15, Volume: 35, Issue:2

    Topics: Aging; Animals; Carbon Radioisotopes; Cell Nucleus; DNA; Female; Fetus; Kidney; Lysine; Methyltransferases; Pregnancy; Proteins; Rats; S-Adenosylmethionine

1973
Protein methylases during the development of rat brain.
    Biochimica et biophysica acta, 1973, Jun-20, Volume: 313, Issue:1

    Topics: Aging; Animals; Body Weight; Brain; Carbon Radioisotopes; Cell Nucleus; Cerebellum; Cytosol; Liver; Lysine; Medulla Oblongata; Mesencephalon; Methionine; Methyltransferases; Mice; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Tritium

1973
Course of the increase in hydroxyindole-O-methyltransferase activity in the pineal gland of the chick embryo and young chick.
    Journal of neurochemistry, 1974, Volume: 22, Issue:1

    Topics: Aging; Animals; Chick Embryo; Chickens; Circadian Rhythm; Darkness; Female; Light; Male; Methyltransferases; Pineal Gland; S-Adenosylmethionine; Serotonin; Time Factors

1974
Transfer ribonucleic acid methylase activity in the developing pig brain.
    Biochemistry, 1971, Jun-22, Volume: 10, Issue:13

    Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Isotopes; Cerebellum; Corpus Callosum; Dialysis; Escherichia coli; Fasting; Female; Fetus; Freezing; Frontal Lobe; Medulla Oblongata; Mesencephalon; Methyltransferases; Pons; Pregnancy; RNA, Transfer; S-Adenosylmethionine; Swine; Transferases

1971
[Transmethylation processes in senile involution: a working hypothesis].
    Giornale di gerontologia, 1971, Volume: 19, Issue:9

    Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12

1971
Polyamines. (1) Enhanced s-adenosyl-L-methionine decarboxylase in rapid growth systems, and (2) the relationships between polyamine concentration and RNA accumulation.
    Biochimica et biophysica acta, 1971, Jun-30, Volume: 240, Issue:2

    Topics: Aging; Amines; Animals; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chick Embryo; Enzyme Induction; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Male; Methionine; Ornithine; Polyamines; Rats; RNA; S-Adenosylmethionine; Spermine; Time Factors; Tritium; Uridine

1971