s-1108 has been researched along with Leukopenia* in 1 studies
1 trial(s) available for s-1108 and Leukopenia
Article | Year |
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[Clinical study of S-1108 fine granule in the pediatric field].
S-1108 in a fine granular form was administered in 14 children and its safety and efficacy in bacterial infections were evaluated. Among them, 2 cases of cystitis and 1 case of pneumonia were considered unevaluable for the efficacy. The results obtained are summarized as follows. 1. The overall clinical efficacy rate was 81.8% in the eleven evaluable cases treated with S-1108 fine granules including 5 cases of pharyngitis, 2 cases each of tonsillitis, pertussis and cystitis. 2. Bacteriological efficacy of 100% was achieved against pathogens identified in 5 children including 1 case each of Staphylococcus aureus, Streptococcus pyogenes and Haemophilus influenzae and 2 cases of Escherichia coli. 3. The only abnormal laboratory test results observed were eosinophilia and leukocytopenia in one case each. Diarrhea was recorded in 1 case. Judging from the above results, it appears that S-1108 in the fine granular form is an effective, useful and safe antibiotic of first choice for the treatment of infections in the pediatric field. Topics: Administration, Oral; Bacterial Infections; Cephalosporins; Child; Child, Preschool; Diarrhea; Female; Humans; Infant; Leukopenia; Male; Prodrugs | 1993 |