s-1-(combination) has been researched along with Paget-Disease--Extramammary* in 8 studies
8 other study(ies) available for s-1-(combination) and Paget-Disease--Extramammary
Article | Year |
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Case of metastatic extramammary Paget's disease treated with trastuzumab-biosimilar monotherapy after S-1 and docetaxel combination chemotherapy.
Topics: Aged; Antineoplastic Agents; Biosimilar Pharmaceuticals; Delayed Diagnosis; Docetaxel; Drug Combinations; Drug Therapy, Combination; Humans; Male; Oxonic Acid; Paget Disease, Extramammary; Prognosis; Skin Neoplasms; Tegafur; Trastuzumab | 2020 |
S-1 in combination with docetaxel as salvage therapy for patients with metastatic extramammary Paget's disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Combinations; Female; Humans; Male; Middle Aged; Oxonic Acid; Paget Disease, Extramammary; Progression-Free Survival; Retrospective Studies; Salvage Therapy; Skin Neoplasms; Survival Rate; Tegafur | 2020 |
Successful treatment of extramammary Paget's disease with S-1 and docetaxel combination chemotherapy.
Topics: Adenocarcinoma of Lung; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Docetaxel; Drug Combinations; Humans; Lung Neoplasms; Male; Oxonic Acid; Paget Disease, Extramammary; Pneumonectomy; Positron-Emission Tomography; Skin Neoplasms; Tegafur; Treatment Outcome | 2018 |
Intratumor dihydropyrimidine dehydrogenase mRNA expression levels are decreased in extramammary Paget's disease.
S-1, a 5-fluorouracil (5-FU)-based anti-cancer agent, is an important drug for treating metastatic extramammary Paget's disease (EMPD). Although intratumor expression levels of 5-FU metabolism enzymes have been studied widely in many solid tumors, no studies have examined on the expression levels of thymidylate synthase (TS), orotate phosphoribosyl-transferase (OPRT) or dihydropyrimidine dehydrogenase (DPD) in skin cancers. The aim of this study was to estimate the intratumoral mRNA expression levels of these genes in EMPD by real time PCR. Intratumoral DPD mRNA levels were decreased in EMPD compared to those in normal skin, but its intratumoral DPD mRNA expression levels were not correlated with clinical manifestations. Intratumoral DPD mRNA levels were positively correlated with OPRT mRNA levels in EMPD. Based on these results, low expression of intratumoral DPD mRNA in EMPD may contribute to the pathogenesis of this disease. Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Female; Humans; Male; Middle Aged; Orotate Phosphoribosyltransferase; Oxonic Acid; Paget Disease, Extramammary; RNA, Messenger; Skin Neoplasms; Tegafur; Thymidylate Synthase | 2017 |
Achieved good response of S-1 and docetaxel combination chemotherapy in two patients with metastatic extramammary Paget's disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Combinations; Fatal Outcome; Humans; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Oxonic Acid; Paget Disease, Extramammary; Prognosis; Spinal Neoplasms; Tegafur | 2017 |
Successful treatment of bilateral multiple lymph node metastases in extramammary Paget's disease with surgery and sequential chemotherapy of S-1 and docetaxel.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Docetaxel; Drug Combinations; Humans; Lymphatic Metastasis; Male; Oxonic Acid; Paget Disease, Extramammary; Taxoids; Tegafur | 2015 |
S-1 induced a durable response in metastatic extramammary Paget's disease.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Combinations; Genital Neoplasms, Male; Humans; Male; Oxonic Acid; Paget Disease, Extramammary; Tegafur | 2013 |
Successful treatment of metastatic extramammary Paget's disease with S-1 and docetaxel combination chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Docetaxel; Drug Combinations; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Oxonic Acid; Paget Disease, Extramammary; Skin Neoplasms; Taxoids; Tegafur; Tomography, X-Ray Computed; Urinary Bladder Neoplasms | 2011 |