s-1-(combination) and Biliary-Tract-Diseases

s-1-(combination) has been researched along with Biliary-Tract-Diseases* in 2 studies

Other Studies

2 other study(ies) available for s-1-(combination) and Biliary-Tract-Diseases

Article	Year
[A case of advanced gastric cancer with pyloric stenosis and obstructive jaundice responding to s-1/paclitaxel combination therapy after endoscopic balloon dilatation and endoscopic biliary drainage]. Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:1 A 65-year-old female who complained of appetite loss and upper abdominal pain was diagnosed as unresectable advanced gastric cancer with pyloric stenosis and obstructive jaundice by peritoneal and lymph node metastases. After endoscopic balloon dilatation and endoscopic biliary drainage, S-1(80 mg/m(2)/day, days 1-14 with 1 week rest)/pacli- taxel(PTX)(50 mg/m(2)/day, day 1, day 8)combination therapy was done. After one course of the chemotherapy, subjective symptoms were relieved and oral intake was increased. Computed tomography showed that the volume of gastric wall, the size of paraaortic lymph node, and the amount of pleural effusion and ascites were decreased. Grade 1 alopecia, vasculitis and grade 2 neutropenia were observed as adverse reactions to the treatment. S-1/PTX combination therapy after endoscopic intervention was effective in this case of advanced gastric cancer with pyloric stenosis and obstructive jaundice. Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Diseases; Catheterization; Drug Combinations; Endoscopes; Female; Humans; Jaundice, Obstructive; Neoplasm Staging; Oxonic Acid; Paclitaxel; Pyloric Stenosis; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed	2008
[A case of advanced gallbladder cancer with biliary tract stenosis which responded to TS-1 chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:7 TS-1 is reported to be beneficial for advanced gastric cancer, but there is no report on its use for advanced gallbladder cancer. The present patient was a 64-year-old woman with advanced gallbladder cancer with severe biliary tract stenosis. The primary tumor was located in the neck of the gallbladder and peripancreatic lymph node metastasis was detected. TS-1 100 mg/day was administered orally for 21 days and CDDP 30 mg/day on days 1, 8 by drip infusion. Grade 4 neutropenia was observed in the first cycle, and TS-1 alone was used for further treatment. After 2 courses, primary tumor showed PR and lymph node metastasis had disappeared. Biliary stenosis was remarkably improved. We conclude that TS-1 might be beneficial in the treatment of advanced gallbladder cancer. Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Diseases; Cisplatin; Constriction, Pathologic; Drug Administration Schedule; Drug Combinations; Female; Gallbladder Neoplasms; Humans; Lymphatic Metastasis; Middle Aged; Oxonic Acid; Pyridines; Tegafur	2003

Article

Year

[A case of advanced gastric cancer with pyloric stenosis and obstructive jaundice responding to s-1/paclitaxel combination therapy after endoscopic balloon dilatation and endoscopic biliary drainage].

Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:1

A 65-year-old female who complained of appetite loss and upper abdominal pain was diagnosed as unresectable advanced gastric cancer with pyloric stenosis and obstructive jaundice by peritoneal and lymph node metastases. After endoscopic balloon dilatation and endoscopic biliary drainage, S-1(80 mg/m(2)/day, days 1-14 with 1 week rest)/pacli- taxel(PTX)(50 mg/m(2)/day, day 1, day 8)combination therapy was done. After one course of the chemotherapy, subjective symptoms were relieved and oral intake was increased. Computed tomography showed that the volume of gastric wall, the size of paraaortic lymph node, and the amount of pleural effusion and ascites were decreased. Grade 1 alopecia, vasculitis and grade 2 neutropenia were observed as adverse reactions to the treatment. S-1/PTX combination therapy after endoscopic intervention was effective in this case of advanced gastric cancer with pyloric stenosis and obstructive jaundice.

Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Diseases; Catheterization; Drug Combinations; Endoscopes; Female; Humans; Jaundice, Obstructive; Neoplasm Staging; Oxonic Acid; Paclitaxel; Pyloric Stenosis; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed

2008

[A case of advanced gallbladder cancer with biliary tract stenosis which responded to TS-1 chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:7

TS-1 is reported to be beneficial for advanced gastric cancer, but there is no report on its use for advanced gallbladder cancer. The present patient was a 64-year-old woman with advanced gallbladder cancer with severe biliary tract stenosis. The primary tumor was located in the neck of the gallbladder and peripancreatic lymph node metastasis was detected. TS-1 100 mg/day was administered orally for 21 days and CDDP 30 mg/day on days 1, 8 by drip infusion. Grade 4 neutropenia was observed in the first cycle, and TS-1 alone was used for further treatment. After 2 courses, primary tumor showed PR and lymph node metastasis had disappeared. Biliary stenosis was remarkably improved. We conclude that TS-1 might be beneficial in the treatment of advanced gallbladder cancer.

Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Diseases; Cisplatin; Constriction, Pathologic; Drug Administration Schedule; Drug Combinations; Female; Gallbladder Neoplasms; Humans; Lymphatic Metastasis; Middle Aged; Oxonic Acid; Pyridines; Tegafur

2003