ryanodine and Ureteral-Calculi

ryanodine has been researched along with Ureteral-Calculi* in 1 studies

Other Studies

1 other study(ies) available for ryanodine and Ureteral-Calculi

ArticleYear
Evaluation of indices of skeletal muscle contraction in areas of referred hyperalgesia from an artificial ureteric stone in rats.
    Neuroscience letters, 2003, Mar-06, Volume: 338, Issue:3

    This study examined indices of skeletal muscle contraction in a rat model of referred muscle hyperalgesia from artificial ureteric calculosis [left oblique muscle (OE) for ipsilateral stone]. In specimens from the left versus right OE of stone-implanted female rats, a significant increase was found in membrane fluidity (P<0.01) and Ca(2+)-ATPase activity (P<0.0001) and a significant decrease in 3H-ryanodine binding (P<0.0001) and in I band length/sarcomere length ratio (contraction index) (P<0.01). The increase in Ca(2+)-ATPase activity was directly and significantly related to the number of rats' ureteral 'crises' (P<0.02). The results indicate a state of contraction in the hyperalgesic muscle, whose extent correlates to the algogenic activity of the ureteral stone.

    Topics: Animals; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Female; Hyperalgesia; Membrane Fluidity; Microscopy, Electron; Models, Animal; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcoplasmic Reticulum; Ureteral Calculi

2003