rutin has been researched along with Schizophrenia* in 2 studies
1 trial(s) available for rutin and Schizophrenia
Article | Year |
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Benzo-pyrones in the treatment of chronic schizophrenic diseases.
Sixteen chronic schizophrenic subjects were treated for 3 months each with either a benzo-pyrone (Paroven/Venoruton, Zyma) or a placebo in a randomized, double-blind crossover trial. They continued to take their previous drug therapies. Therapeutic effects were measured by the Brief Psychiatric Rating Scale (BPRS), by self-assessment, and by assessment by a relative. Eleven patients completed the trial in relation to BPRS assessment. When on the active substance, as compared with the placebo, they showed a mean improvement of 27% (significant at the 1% level). Ten patients completed the trial in relation to the self and relative's assessments. There were improvements of 16% and 13%, respectively (significant at the 5% levels). Half the patients showed improvements on all the tests. Their improvements were 49%, 31%, and 21%, respectively. There was evidence that the active substance began to have an effect within 2 weeks. No side effects were observed with the active substance. Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxyethylrutoside; Male; Middle Aged; Rutin; Schizophrenia | 1986 |
1 other study(ies) available for rutin and Schizophrenia
Article | Year |
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Benzopyrones in treatment of schizophrenia.
Topics: Adult; Blister; Coumarins; Drug Combinations; Humans; Hydroxyethylrutoside; Male; Rutin; Schizophrenia | 1983 |