rutin and Heart-Failure

We report the case of a 55-year-old woman with heart failure with preserved ejection fraction (HFpEF), who presented with hypertensive urgency and pulmonary oedema. The patient was medically optimized and underwent cardiac catheterization revealing pulmonary hypertension, elevated pulmonary capillary wedge pressure, normal cardiac index, and non-obstructive coronary disease. Invasive evaluation of coronary flow revealed blunted coronary flow reserve and increased index of microvascular resistance. Cardiac magnetic resonance imaging demonstrated reduced global myocardial perfusion and diffuse interstitial fibrosis. This case exhibits a potential HFpEF phenotype associated with microvascular dysfunction, fibrosis, and elevated filling pressures.

Topics: Cardiomyopathies; Coronary Angiography; Coronary Circulation; Coronary Vessels; Echocardiography; Electrocardiography; Female; Fibrosis; Heart Failure; Humans; Hydroxyethylrutoside; Microcirculation; Middle Aged; Myocardium; Pulmonary Wedge Pressure; Stroke Volume; Ventricular Function, Left