Page last updated: 2024-08-22

ruthenium and Neoplasms

ruthenium has been researched along with Neoplasms in 197 studies

Research

Studies (197)

TimeframeStudies, this research(%)All Research%
pre-19907 (3.55)18.7374
1990's0 (0.00)18.2507
2000's10 (5.08)29.6817
2010's117 (59.39)24.3611
2020's63 (31.98)2.80

Authors

AuthorsStudies
Chen, M; Cheng, J; Hu, Y; Jiang, Z; Li, Y; Liu, M; Liu, Y; Qu, Y; Wang, H; Wang, W; Wang, Z; Wu, Y; Xiong, C; Xue, Z; Zhang, H; Zhao, Y; Zhou, F; Zhou, H; Zhu, X; Zhu, Y1
Brindell, M; Gajda-Morszewski, P; Gurgul, I; Janczy-Cempa, E; Mazuryk, O1
Chen, DS; Deng, H; Ding, Q; Gong, W; Gu, L; Gu, M; Guan, M; Hong, X; Li, Q; Liao, Y; Liu, Y; Lu, D; Pan, Y; Tian, Z; Wu, J; Xiao, Y; Xiong, X; Zhang, Z1
Bo, H; Chen, D; Guo, S; Qiao, A; Rong, Y; Shen, H; Shen, J; Tang, X; Wang, J; Zhao, Z1
Geisler, H; Harringer, S; Jakupec, MA; Kandioller, W; Keppler, BK; Urban, R; Wenisch, D1
Banerjee, S1
Li, ZY; Mao, ZW; Shen, QH; Tan, CP1
Lai, Q; Lin, W; Lu, K; Mao, ZW; Tao, X; Wang, J; Xia, W; Xie, Y; Zhao, Z1
Balakrishnan, A; Dhanapal, AR; Durairaju, N; Infanta S, AKT; Jayaraman, A; Murugesan, T; Muthusamy, P; Natarajan, K; Raja, S; Vedagiri, H1
Bai, S; Fan, Y; Guan, X; Li, C; Ma, X; Sun, Y; Yang, J1
El-Khamisy, SF; Liao, C; Lyon, RF; Poole, RK; Southam, HM; Trevitt, CR; Williamson, MP1
Chao, H; Chen, X; Chen, Y; Ji, L; Karges, J; Lin, X; Liu, J; Ouyang, C; Wan, J; Xiong, K1
Fenton, A; Glazer, EC; Hachey, AC; Havrylyuk, D; Heidary, DK1
Brindell, M; Gros, PC; Gurgul, I; Lekka, M; Mazuryk, O; Olszanecki, R; Stachyra, K; Suzenet, F; Łomzik, M1
Bai, S; Li, C; Liu, C; Sun, Y; Tu, L; Xiong, X; Xu, L; Yang, J; Zhang, X1
Brindell, M; Gros, PC; Gurgul, I; Janczy-Cempa, E; Lekka, M; Mazuryk, O; Suzenet, F; Łomzik, M1
Alessio, E; Burckel, P; Gandioso, A; Gasser, G; Vidal, A1
Huang, J; Liu, J; Liu, Y1
Batista, AA; Cominetti, MR; Correa, RS; de Oliveira, KM; Ellena, J; Godoy, LR; Graminha, AE; Honorato de Araujo-Neto, J; Popolin, C; Vegas, LC1
Hangan, AC; Lucaciu, RL; Oprean, LS; Sevastre, B1
Bonnet, S; Götzfried, SK; Husiev, Y; Klein, DM; Popal, S; Salitra, N; Schneider, GF; Siegler, MA; Van der Griend, CJ; van Geest, EP; Zhou, X1
Fuster, MG; García, G; Montalbán, MG; Moulefera, I; Pérez, J; Víllora, G1
Dominguez-Jurado, E; Gasser, G; Gois, PMP; Karges, J; Saubaméa, B; Silva, MJSA; Tharaud, M; Vinck, R; Wang, Y1
Hong, Y; Khine, YY; Lu, H; Lu, M; Stenzel, MH; Wang, S; Zheng, J1
Etchenique, R; Filevich, O1
Enyedy, ÉA; Kovács, H; May, NV; Nezafat Yazdi, Z; Özvegy-Laczka, C; Pivarcsik, T; Pósa, SP; Pósa, V; Spengler, G; Szakács, G; Szatmári, I; Tóth, S; Ugrai, I1
Chen, C; Lv, H; Shen, C; Xu, H; Zhu, D1
Grishina, M; Kumar Singh, A; Kumar, A; Kumar, P; Pal Yadav, J; Pathak, P; Singh, H; Sonawane, P; Verma, A1
Du, J; Fan, J; He, G; He, M; Hu, H; Li, X; Lu, Y; Peng, X; Sun, W; Wang, D; Wang, R; Wang, Z; Xu, N1
Banerjee, S; Fan, Z; Huang, H; Kushwaha, R; Li, W; Liang, S; Mandal, AA; Wei, L; Xie, J1
Budzisz, E; Hikisz, P; Namiecińska, E; Paneth, P1
Balcerzak, Ł; Bryszewska, M; de la Mata, FJ; Garaiova, Z; Grodzicka, M; Hianik, T; Hołota, M; Ionov, M; Kubczak, M; Michlewska, S; Naziris, N; Okła, E; Ortega, P; Šubjakova, V; Waczulikova, I1
Dharmasivam, M; Dorairaj, DP; Echeverria, C; Haribabu, J; Karvembu, R; Malekshah, RE; Mohamed Subarkhan, MK1
Chen, J; Hu, H; Huang, C; Liang, L; Liu, H; Liu, Y; Wang, Y; Yang, Y; Zhang, H1
Burke, CS; Curley, RC; Gkika, KS; Keyes, TE; Noorani, S; Walsh, N1
Arnoux, P; Bosch, M; Burckel, P; Demeubayeva, N; Frochot, C; Gandioso, A; Gasser, G; Izquierdo-García, E; Marchán, V; Mesdom, P; Saubaméa, B1
Cariou, K; Dömötör, O; Enyedy, ÉA; Gasser, G; Guérineau, V; Jakubaszek, M; Karges, J; Mignet, N; Seguin, J; Tharaud, M; Vinck, R1
Das, S; Dinda, R; Patra, SA; Sahu, G1
Bonnet, S1
Chen, X; Liu, Z; Ma, W; Tian, Z; Xia, X; Xu, Z; Zhang, S; Zhang, Y1
Aranđelović, S; Dojčinović, B; Gligorijević, N; Kaczmarek, AM; Radulović, S; Savić, A; Van Deun, R; Van Hecke, K1
Bai, L; Du, F; Gu, YY; He, M; Jiang, GB; Wang, YJ; Yi, QY; Zhang, WY2
Dyson, PJ; Murray, BS1
Li, YH; Liu, JG; Shi, SW; Yang, SP; Zhang, QL1
Pawlukojć, A; Piotrowski, M; Zuba, I; Zuba, M1
Chao, H; Ji, L; Jin, C; Kuang, S; Liao, X; Liu, J; Xiong, K1
Blower, TR; Cross, JM; Kingdon, ADH; Pal, R; Picton, DM; Walton, JW1
P K, A; Paira, P1
Baldari, S; Cirone, M; Crispini, A; D'Orazi, G; D'Orazi, V; Garufi, A; Gilardini Montani, MS; Giorno, E; Marchetti, F; Pettinari, R; Pistritto, G; Toietta, G1
Ahmad, H; Gill, MR; Yusoh, NA1
Hao, X; Liu, J; Qiu, K; Wang, J; Zhao, Z1
Bai, Y; Chen, Y; Chen, Z; Fang, H; Guo, Z; Han, Z; He, W; Shi, X; Wang, Y; Yuan, H1
Gasser, G; Soliman, N; Thomas, CM1
Allison, M; Caramés-Méndez, P; Lord, RM; McGowan, PC; Pask, CM; Phillips, RM1
Batista, AA; Cominetti, MR; Correa, RS; Demidoff, FC; Honorato, J; Netto, CD; Oliveira, KM; Schultz, MS1
Chao, H; Gasser, G; Karges, J; Li, J; Zeng, L1
Kim, CY; Lee, SY; Nam, TG1
Alessio, E; Balducci, G; Duan, F; Giacomelli, C; La Mendola, D; Marchetti, F; Marchetti, L; Marzo, T; Messori, L; Pettinari, R; Tombesi, A; Trincavelli, ML; Zhou, L1
Arlt, S; Eichhorn, T; Kaluđerović, GN; Lang, H; Ludwig, G; Maksimović-Ivanić, D; Mijatović, S; Petković, V; Rüffer, T1
Gasser, G; Karges, J; Tharaud, M1
Chen, F; He, M; Shao, D; Sun, W; Wei, Z; Weis, P1
Mai Le, NP; Mo, J; Priefer, R1
Huang, C; Huang, H; Liang, C; Luo, S; Xie, J; Zhang, P; Zhang, Q1
Chan, L; Chen, T; Deng, Z; Gao, P; Ma, B; Mei, C; You, Y; Yu, L1
Diserens, G; Furrer, J; Vermathen, M; Vermathen, P1
Kim, S; Thangavel, P; Viswanath, B1
Bugarčić, ŽD; Lazarević, T; Rilak, A1
Accardo, A; Morelli, G; Ringhieri, P1
Bratsos, I; Bugarčić, ŽD; Čanović, P; Demitri, N; Mitrović, M; Radisavljević, S; Simović, AR; Zelen, I1
Batista, AA; Cominetti, MR; Corrêa, RS; Deflon, VM; Liany, LD; Oliveira, KM1
Chen, G; Liu, J; Sun, J; Xu, M; Yu, Q; Zhao, S1
Ahsan, H; Ali, SS; Khan, FH; Rehman, AA; Siddiqui, T; Zia, MK1
Gasser, G; Notaro, A1
Berger, W; Gerner, C; Hartinger, CG; Keppler, BK; Meier-Menches, SM1
Sun, W; Wu, S; Zeng, X1
De, S; Jacob, R; Maiti, S; Mondal, A; Moorthy, A; Paira, P; Sarkar, B; Sk, AK1
Hanif, M; Hartinger, CG1
Collins, KA; Kodanko, JJ; Rohrabaugh, TN; Turro, C; White, JK; Xue, C1
Bai, Y; Cadavid-Vargas, JF; Etcheverry, SB; He, W; Kljun, J; León, IE; Peršič, Š; Turel, I1
Ang, WH; Babak, MV; Cheong, MC; Chow, MJ; Gaiddon, C; Pastorin, G; Tan, KW1
Bandow, JE; Cheng, X; Dabiri, Y; Hager, L; Keppler, BK; Ott, I; Prochnow, P; Streciwilk, W; Terenzi, A; Wölfl, S1
Chapman, JA; Cox, FL; El-Khamisy, SF; Henderson, PJF; Hippler, M; Liao, C; Lyon, RL; Middlemiss, LA; Poole, RK; Smith, TW; Southam, HM; Trevitt, CR; Williamson, MP1
Glazer, EC; Havrylyuk, D; Heidary, DK; Howerton, BS; Nease, L; Parkin, S1
Brewer, KJ; Rodríguez-Corrales, JÁ; Wang, J; Winkel, BSJ1
Cao, JJ; Ji, LN; Mao, ZW; Tan, CP; Zhang, DY; Zhang, H; Zheng, Y1
Cameron, CG; Colón, KL; Gujar, S; Konda, P; Lilge, L; McFarland, SA; Monro, S; Roque, J; Thummel, RP; Yin, H1
Guo, Z; Jin, S; Muhammad, N; Wang, X1
Ferrari, S; Gasser, G; Goud, B; Jakubaszek, M1
Chen, T; Li, CE; Zhang, X; Zhao, Z1
Kenny, RG; Marmion, CJ1
Casari, I; Desai, NM; Falasca, M; Massi, M; Simpson, PV1
Guo, X; Hou, Y; Li, C; Lu, J; Sun, W; Tian, N; Wang, X; Zhou, Q1
Cao, C; Ding, R; Li, X; Shi, Y; Stang, PJ; Teng, M; Zhang, L; Zhang, P; Zhao, Y1
Chen, Y; Fu, HG; Liu, Y; Yu, Q1
Di Virgilio, AL; Kljun, J; León, IE; Ruiz, MC; Turel, I1
Dou, YK; He, XW; Li, WY; Li, YH; Shang, Y; Zhang, YK1
Makovec, T1
Dyson, PJ1
Chen, T; Guo, Z; Huang, RT; Jiang, BP; Liang, H; Lu, Y; Shen, XC; Wang, WL; Wen, C; Zhou, B1
Du, Q; Ge, X; Guo, L; Liu, X; Liu, Z; Tian, Z; Zhang, F; Zhao, L1
Arjmand, F; Parveen, S; Tabassum, S1
Beckford, FA; Fast, OG; Gentry, B; Niece, MB; Shell, SM; Strouth, L1
Gasser, G; Goud, B; Jakubaszek, M; Karges, J; Mari, C; Stephan, H; Zarschler, K1
Cong, H; Liu, D; Lv, F; Shen, Y; Yu, B; Zhang, X1
Chen, S; Chen, T; Chen, Y; Fan, C; Liu, C; Mei, W; Wang, B; Wu, Q; Zheng, W1
Therrien, B1
Aleksenko, SS; Foteeva, LS; Jarosz, M; Lu, X; Matczuk, M; Pawlak, K; Timerbaev, AR1
Chao, H; Chen, Y; Ji, LN; Qin, MY; Wang, L; Xu, AL1
Aitken, JB; Antony, S; Brown, T; Harris, HH; Lai, B; Spiccia, L; Vogt, S1
Huang, HL; Jiang, GB; Liang, ZH; Lin, GJ; Liu, YJ; Xie, YY1
D'Errico, G; Irace, C; Mangiapia, G; Montesarchio, D; Musumeci, D; Paduano, L; Santamaria, R; Vitiello, G1
Gupta, G; Johnpeter, JP; Kumar, JM; Nagesh, N; Srinivas, G; Therrien, B1
Liu, J; Qin, X; Wang, C; Yang, L; Yu, Q; Zhang, J; Zhou, Y1
da Silva, RS; Fukuto, JM; Heinrich, TA; Tedesco, AC1
Kumar, YP; Nambigari, N; Reddy, MR; Reddy, PV; Satyanarayana, S; Srishailam, A1
Chi, KW; Jeong, YJ; Jo, JH; Kang, SC; Lah, MS; Mishra, A1
Li, ZS; Liu, P; Song, XM; Wang, KZ; Zhang, AG; Zhao, XL1
Huang, Y; Liu, J; Liu, Y; Sun, J; Zheng, C; Zhou, Y1
Hara, D; Ito, T; Kawasaki, A; Son, A; Tanabe, K1
Cao, W; Chen, T; Deng, Z; Yu, L; Zheng, W1
Brindell, M; Kieda, C; Mazuryk, O; Suzenet, F1
Clavel, CM; Dyson, PJ; Griffioen, AW; Nowak-Sliwinska, P; Păunescu, E; Scopelliti, R1
Allison, SJ; Hebden, AJ; Henderson, IR; Lord, RM; McGowan, PC; Pask, CM; Phillips, RM; Shepherd, SL1
Bhavsar, D; Chen, LM; Chen, Q; Liu, J; Liu, Y; Ren, X; Sun, D; Yang, L; Yu, Q; Zheng, W1
Arcangeli, A; Contel, M; Fernández-Gallardo, J; Guerri, A; Massai, L; Messori, L; Pillozzi, S1
Diserens, G; Furrer, J; Paul, LE; Vermathen, M; Vermathen, P1
Liu, S; Luo, Q; Wang, F; Zhang, E; Zhang, Y; Zhao, Y; Zheng, W1
Fischer, S; Lamla, M; Monczak, K; Ng, DY; Rau, S; Wang, T; Weil, T; Wu, Y; Zabarska, N1
Chen, H; Dong, L; Ge, X; Huang, W; Jin, D; Li, N; Ma, B; Shi, L; Sun, L1
Chao, H; Chen, Y; Huang, H; Ji, L; Zhang, P1
Bergamo, A; Brescacin, L; Masi, A; Sava, G1
Ding, Y; Mei, W; Wu, Q; Zheng, K1
Abid, M; Azam, A; Shamsi, F1
Balacescu, L; Balacescu, O; Berindan-Neagoe, I; Cheminel, T; Grozav, A; Therrien, B1
Jia, J; Liu, P; Wang, KZ; Zhao, Y1
Elmes, RB; Gunnlaugsson, T; la Cour Poulsen, B; Martínez-Calvo, M; Orange, KN; Williams, DC1
Butt, HJ; Mailänder, V; Parowatkin, M; Steffen, W; Sun, W; Wu, S1
Ajibade, PA; Ejidike, IP1
Brustolin, L; Fregona, D; Nardon, C1
Cao, DH; Guo, QF; Liang, JB; Lin, YY; Liu, SH; Liu, YM; Wang, Y; Wu, Y; Xu, HH; Zhang, GQ; Zhu, JW1
Garcia, MH; Marques, F; Morais, TS; Tomaz, AI; Valente, A1
Thota, S1
Li, P; Su, W; Tang, Z1
Biersack, B1
de França Lopes, LG; Gouveia, FS; Ridnour, LA; Sadler, PJ; Silva da Silva, CD; Silva Sousa, EH; Wink, DA1
Chao, H; Ji, L; Qian, C; Wu, J1
Mei, W; Tan, W; Wang, C; Wu, Q; Zheng, K1
Barbosa, MI; Batista, AA; Carnizello, AP; Ferreira, NH; Magalhães, GM; Martins, M; Oliveira, PF; Tavares, DC1
Li, N; Mou, Z; Sun, D; Wang, W; Wang, Y; Yang, E; Zhang, W1
Gobec, S; Kljun, J; Kos, J; Mitrović, A; Sosič, I; Turel, I1
Butt, HJ; Häupler, B; Jin, S; Li, S; Liang, XJ; Liu, J; Schubert, US; Steffen, W; Sun, W; Wu, S1
Ali, M; Armant, O; Capuozzo, A; Cianferani, S; Delalande, F; Gaiddon, C; Licona, C; Mellitzer, G; Pfeffer, M; Santamaria, R; Spaety, ME; Spencer, J; Van Dorsselaer, A1
Cheah, KW; Chelora, J; Chen, R; Kershaw, SV; Lee, CS; Li, KF; Lo, PK; Rogach, AL; Xiong, Y; Zapien, JA; Zhang, J1
Cao, R; He, N; Huang, FY; Huang, J; Lu, Z; Tan, GH; Wang, G; Zhang, L; Zhang, Z1
Prudhomme, M1
Fry, NL; Hinck, L; Marlow, R; Mascharak, PK; Rose, MJ1
Brabec, V; Bugarcic, T; Habtemariam, A; Halámiková, A; Kaspárková, J; Nováková, O; Parsons, S; Sadler, PJ; Vrána, O; Zerzánková, L1
Govindaswamy, P; Juillerat-Jeanneret, L; Schmitt, F; Süss-Fink, G; Therrien, B; Zava, O1
Ford, PC; Ostrowski, AD1
Fregona, D; Ronconi, L1
Arion, VB; Gligorijević, N; Grgurić-Sipka, S; Ivanović, I; Keppler, BK; Radulović, S; Rakić, G; Tesić, ZLj; Todorović, N1
Dyson, PJ; Renfrew, AK; Scopelliti, R1
Silva, Dde O1
Bi, S; Hao, S; Li, L; Zhang, S1
Ducani, C; Hannon, MJ; Hodges, NJ; Leczkowska, A1
Fry, NL; Heilman, BJ; Mascharak, PK1
Barker, PD; Boss, SR; Page, SM1
León, LG; Lorenzo-Luis, P; Mena-Cruz, A; Padrón, JM; Pérez-Roth, E; Ríos-Luci, C; Romerosa, A1
Barragán, F; Betanzos-Lara, S; Habtemariam, A; López-Senín, P; Marchán, V; Moreno, V; Sadler, PJ; Salassa, L1
Bogdanović, A; Dulović, M; Grgurić-Šipka, S; Jovanović, M; Marković, I; Misirlić-Denčić, S; Poljarević, JM; Sabo, TJ; Savić, A; Trajković, V1
Smith, GS; Therrien, B1
Alborzinia, H; Baumann, K; Ludewig, S; Oehninger, L; Ott, I; Wölfl, S1
Maresca, A; Poulsen, SA; Salmon, AJ; Supuran, CT; Williams, ML1
Furrer, J; Giannini, F; Süss-Fink, G1
Dyson, PJ; Groessl, M1
Hartinger, CG; Nazarov, AA; Phillips, AD1
Beijnen, JH; Bergamo, A; Gaiddon, C; Sava, G; Schellens, JH1
Barry, NP; Juillerat-Jeanneret, L; Schmitt, F; Therrien, B1
Colonna, A; D'Errico, G; Di Pascale, A; Irace, C; Mangiapia, G; Montesarchio, D; Paduano, L; Radulescu, A; Simeone, L1
Jin, L; Liu, J; Shen, J; Tan, L; Weng, C; Zeng, L1
Glazer, EC; Heidary, DK; Howerton, BS1
Fregona, D; Nagy, EM; Nardon, C; Ronconi, L1
Cao, W; Chen, T; Fan, C; Li, L; Zheng, W1
Angeletti, M; Bonfili, L; Cecarini, V; Cuccioloni, M; Eleuteri, AM; Lupidi, G; Marchetti, F; Mozzicafreddo, M; Pettinari, C; Pettinari, R1
Downward, AM; Hartshorn, RM; Jane, RT; Moore, EG; Polson, MI1
FRUIN, RC; LITTMAN, A; LITTMAN, MS1
ALTSHULER, B; DANIELS, M; HARLEY, JH; KUSCHNER, M; LASKIN, S; NELSON, N1
ALTSHULER, B; KUSCHNER, M; LASKIN, S; NELSON, N1
DWYER, FP; MAYHEW, E; ROE, EM; SHULMAN, A1
Alessio, E; Bergamo, A; Casarsa, C; Cocchietto, M; Sava, G; Serli, B; Stocco, G; Zorzet, S1
Cocchietto, M; Frausin, F; Furlani, A; Podda, E; Sava, G; Scarcia, V; Spessotto, P; Vita, F; Zabucchi, G1
Groessl, M; Hann, S; Hartinger, CG; Keppler, BK; Koellensperger, G; Rudnev, AV; Stingeder, G; Sulyok, M; Timerbaev, AR1
Aleksenko, SS; Hartinger, CG; Keppler, BK; Timerbaev, AR1
Anghileri, LJ1
Wenzel, M1
Rudolph, R1

Reviews

44 review(s) available for ruthenium and Neoplasms

ArticleYear
Moving Ru polypyridyl complexes beyond cytotoxic activity towards metastasis inhibition.
    Journal of inorganic biochemistry, 2022, Volume: 226

    Topics: Antineoplastic Agents; Apoptosis; Cell Movement; Coordination Complexes; Humans; Neoplasm Metastasis; Neoplasms; Pyridines; Ruthenium

2022
Rising Interest in the Development of Metal Complexes in Cancer Immunotherapy.
    Chemistry, an Asian journal, 2022, Jul-01, Volume: 17, Issue:13

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Immunotherapy; Iridium; Neoplasms; Ruthenium

2022
Metallo-Drugs in Cancer Therapy: Past, Present and Future.
    Molecules (Basel, Switzerland), 2022, Oct-01, Volume: 27, Issue:19

    Topics: Antineoplastic Agents; Coordination Complexes; Copper; Humans; Neoplasms; Platinum; Ruthenium

2022
Metal Complexes in Cancer Treatment: Journey So Far.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:4

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Humans; Neoplasms; Ruthenium

2023
Recent Advances in Mitochondria-Localized Luminescent Ruthenium(II) Metallodrugs as Anticancer Agents.
    ChemMedChem, 2023, Nov-16, Volume: 18, Issue:22

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Mitochondria; Neoplasms; Ruthenium

2023
Ruthenium-Based Photoactivated Chemotherapy.
    Journal of the American Chemical Society, 2023, 11-01, Volume: 145, Issue:43

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium

2023
Recent progress in the development of organometallics for the treatment of cancer.
    Current opinion in chemical biology, 2020, Volume: 56

    Topics: Animals; Antineoplastic Agents; Chromatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Gold; Humans; Models, Molecular; Neoplasms; Organometallic Compounds; Photochemotherapy; Platinum; Ruthenium; Silver

2020
Ruthenium as an important element in nuclear energy and cancer treatment.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 162

    Topics: Humans; Neoplasms; Nuclear Energy; Radioisotopes; Ruthenium

2020
Combining PARP Inhibition with Platinum, Ruthenium or Gold Complexes for Cancer Therapy.
    ChemMedChem, 2020, 11-18, Volume: 15, Issue:22

    Topics: Antineoplastic Agents; Coordination Complexes; Gold; Humans; Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Ruthenium

2020
Incorporation of Ru(II) Polypyridyl Complexes into Nanomaterials for Cancer Therapy and Diagnosis.
    Advanced materials (Deerfield Beach, Fla.), 2020, Volume: 32, Issue:47

    Topics: Animals; Coordination Complexes; Humans; Nanomedicine; Nanostructures; Neoplasms; Pyridines; Ruthenium

2020
Ruthenium Complexes as Anticancer Agents: A Brief History and Perspectives.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium

2020
Photoresponsive metallopolymer nanoparticles for cancer theranostics.
    Biomaterials, 2021, Volume: 275

    Topics: Humans; Nanoparticles; Neoplasms; Phototherapy; Precision Medicine; Ruthenium

2021
Evaluating the mechanisms of action and subcellular localization of ruthenium(II)-based photosensitizers.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium

2021
Recent developments in the nanostructured materials functionalized with ruthenium complexes for targeted drug delivery to tumors.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Ligands; Nanostructures; Neoplasms; Photochemotherapy; Ruthenium; Ruthenium Compounds

2017
Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Drug Discovery; Gold; Humans; Neoplasms; Palladium; Platinum; Ruthenium

2017
Supramolecular Delivery Systems for Non-Platinum Metal-Based Anticancer Drugs.
    Critical reviews in therapeutic drug carrier systems, 2017, Volume: 34, Issue:2

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Neoplasms; Ruthenium

2017
Chemotherapeutic Drugs and Plasma Proteins: Exploring New Dimensions.
    Current protein & peptide science, 2018, Volume: 19, Issue:10

    Topics: Antineoplastic Agents; Blood Proteins; Cell Survival; Cisplatin; Coordination Complexes; Fluorouracil; Humans; Neoplasms; Platinum; Ruthenium

2018
Monomeric and dimeric coordinatively saturated and substitutionally inert Ru(ii) polypyridyl complexes as anticancer drug candidates.
    Chemical Society reviews, 2017, Nov-27, Volume: 46, Issue:23

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Proliferation; Coordination Complexes; Humans; Neoplasms; Pyridines; Ruthenium

2017
Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development.
    Chemical Society reviews, 2018, Feb-05, Volume: 47, Issue:3

    Topics: Antineoplastic Agents; Cell Proliferation; Humans; Neoplasms; Organometallic Compounds; Osmium; Ruthenium; Structure-Activity Relationship

2018
Photoresponsive ruthenium-containing polymers: potential polymeric metallodrugs for anticancer phototherapy.
    Dalton transactions (Cambridge, England : 2003), 2018, Jan-02, Volume: 47, Issue:2

    Topics: Neoplasms; Organometallic Compounds; Photosensitizing Agents; Phototherapy; Ruthenium

2018
Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433.
    Chemical reviews, 2019, 01-23, Volume: 119, Issue:2

    Topics: Clinical Trials as Topic; Coordination Complexes; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium; Transition Elements

2019
Stimuli-Responsive Therapeutic Metallodrugs.
    Chemical reviews, 2019, 01-23, Volume: 119, Issue:2

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Hydrogen-Ion Concentration; Light; Neoplasms; Oxidation-Reduction; Platinum; Ruthenium; Temperature

2019
Mechanisms of action of Ru(ii) polypyridyl complexes in living cells upon light irradiation.
    Chemical communications (Cambridge, England), 2018, Nov-20, Volume: 54, Issue:93

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Humans; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polymers; Pyridines; Ruthenium

2018
Toward Multi-Targeted Platinum and Ruthenium Drugs-A New Paradigm in Cancer Drug Treatment Regimens?
    Chemical reviews, 2019, 01-23, Volume: 119, Issue:2

    Topics: ATP-Binding Cassette Transporters; Coordination Complexes; DNA Damage; Enzymes; Humans; Neoplasms; Platinum; Prodrugs; Ruthenium

2019
Metal-based antitumor compounds: beyond cisplatin.
    Future medicinal chemistry, 2019, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cisplatin; Copper; Drug Discovery; Gold; Humans; Iridium; Iron; Metals; Neoplasms; Organometallic Compounds; Rhenium; Rhodium; Ruthenium

2019
Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy.
    Radiology and oncology, 2019, 03-28, Volume: 53, Issue:2

    Topics: Antineoplastic Agents; Cisplatin; DNA Adducts; DNA Repair; DNA, Neoplasm; Drug Hypersensitivity; Drug Resistance, Neoplasm; Gold Compounds; Humans; Neoplasms; Organometallic Compounds; Palladium; Platinum Compounds; Polymorphism, Genetic; Ruthenium

2019
Development and future prospects of selective organometallic compounds as anticancer drug candidates exhibiting novel modes of action.
    European journal of medicinal chemistry, 2019, Aug-01, Volume: 175

    Topics: Antineoplastic Agents; Cathepsin B; Cell Line; Cell Line, Tumor; DNA Topoisomerases; ErbB Receptors; Gold; Humans; Neoplasms; Nucleic Acids; Organometallic Compounds; Ruthenium; Thioredoxin-Disulfide Reductase; Titanium; Transferrin

2019
Recent advances in ruthenium and platinum based supramolecular coordination complexes for antitumor therapy.
    Colloids and surfaces. B, Biointerfaces, 2019, Oct-01, Volume: 182

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Humans; Mice; Molecular Structure; Neoplasms; Platinum; Ruthenium; Xenograft Model Antitumor Assays

2019
Arene ruthenium(II) Complexes: The Promising Chemotherapeutic Agent in Inhibiting the Proliferation, Migration and Invasion.
    Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Coordination Complexes; Humans; Hydrocarbons, Aromatic; Neoplasm Invasiveness; Neoplasms; Ruthenium

2016
Ruthenium Complexes: An Emerging Ground to the Development of Metallopharmaceuticals for Cancer Therapy.
    Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:10

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; DNA; DNA Damage; Drug Discovery; Humans; Neoplasms; Ruthenium

2016
Recent Advances on Dark and Light-Activated Cytotoxity of Imidazole-Containing Ruthenium Complexes.
    Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:4

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Dimethyl Sulfoxide; DNA; Humans; Imidazoles; Light; Models, Molecular; Neoplasms; Organometallic Compounds; Ruthenium; Ruthenium Compounds

2016
Is matching ruthenium with dithiocarbamato ligands a potent chemotherapeutic weapon in oncology?
    Future medicinal chemistry, 2016, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Coordination Complexes; Dimethyl Sulfoxide; Humans; Ligands; Neoplasms; Organometallic Compounds; Ruthenium; Ruthenium Compounds

2016
Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds.
    Future medicinal chemistry, 2016, Volume: 8, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Cyclopentanes; Dimethyl Sulfoxide; Drug Discovery; Ferrous Compounds; Humans; Indazoles; Molecular Targeted Therapy; Neoplasms; Organometallic Compounds; Protein Binding; Ruthenium; Ruthenium Compounds

2016
Development of Arene Ruthenium Antitumor Complexes.
    Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:10

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Drug Discovery; Humans; Hydrocarbons, Aromatic; Neoplasms; Ruthenium

2016
Anticancer Activity and Modes of Action of (arene) ruthenium(II) Complexes Coordinated to C-, N-, and O-ligands.
    Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:10

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; DNA; Drug Discovery; Humans; Hydrocarbons, Aromatic; Ligands; Neoplasms; Ruthenium

2016
Ruthenium(II) Complexes as Potential Apoptosis Inducers in Chemotherapy.
    Anti-cancer agents in medicinal chemistry, 2017, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Coordination Complexes; DNA Damage; Drug Discovery; Endoplasmic Reticulum Stress; G-Quadruplexes; Humans; Mitochondria; Neoplasms; Ruthenium; Signal Transduction

2017
Perspectives for novel mixed diruthenium-organic drugs as metallopharmaceuticals in cancer therapy.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Dimethyl Sulfoxide; Glioblastoma; Humans; Indazoles; Ligands; Neoplasms; Organometallic Compounds; Organoplatinum Compounds; Rats; Ruthenium; Ruthenium Compounds; Solubility

2010
Tuning heavy metal compounds for anti-tumor activity: is diversity the key to ruthenium's success?
    Future medicinal chemistry, 2009, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Neoplasms; Platinum; Ruthenium

2009
Targeted and multifunctional arene ruthenium chemotherapeutics.
    Dalton transactions (Cambridge, England : 2003), 2011, Nov-07, Volume: 40, Issue:41

    Topics: Cell Proliferation; Coordination Complexes; Humans; Neoplasms; Photosensitizing Agents; Porphyrins; Ruthenium

2011
Bioanalytical and biophysical techniques for the elucidation of the mode of action of metal-based drugs.
    Current topics in medicinal chemistry, 2011, Volume: 11, Issue:21

    Topics: Antineoplastic Agents; Chemistry Techniques, Analytical; DNA; Drug Delivery Systems; Gallium; Gold; Humans; Microscopy, Fluorescence; Neoplasms; Organometallic Compounds; Proteins; Ruthenium; Titanium

2011
Polynuclear ruthenium, osmium and gold complexes. The quest for innovative anticancer chemotherapeutics.
    Current topics in medicinal chemistry, 2011, Volume: 11, Issue:21

    Topics: Antineoplastic Agents; Coordination Complexes; Cross-Linking Reagents; DNA; Enzyme Inhibitors; Gold; Humans; Models, Molecular; Neoplasms; Organometallic Compounds; Osmium; Photochemical Processes; Ruthenium

2011
Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates.
    Journal of inorganic biochemistry, 2012, Volume: 106, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Survival; Clinical Trials as Topic; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Organometallic Compounds; Ruthenium

2012
Noble metal-dithiocarbamates precious allies in the fight against cancer.
    Mini reviews in medicinal chemistry, 2012, Volume: 12, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Coordination Complexes; Copper; Gold; Humans; Neoplasms; Palladium; Platinum; Ruthenium; Thiocarbamates

2012
Interactions of antitumor metallodrugs with serum proteins: advances in characterization using modern analytical methodology.
    Chemical reviews, 2006, Volume: 106, Issue:6

    Topics: Animals; Antineoplastic Agents; Binding Sites; Blood Proteins; Cisplatin; Drug Interactions; Electrophoresis, Gel, Two-Dimensional; Humans; Neoplasms; Protein Binding; Protein Conformation; Ruthenium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship

2006

Other Studies

153 other study(ies) available for ruthenium and Neoplasms

ArticleYear
Biocompatible Ruthenium Single-Atom Catalyst for Cascade Enzyme-Mimicking Therapy.
    ACS applied materials & interfaces, 2021, Sep-29, Volume: 13, Issue:38

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carbon; Catalysis; Cell Line, Tumor; Glutathione; Hydrogen Peroxide; Kinetics; Mice; Neoplasms; Oxidation-Reduction; Oxidative Stress; Quantum Dots; Ruthenium

2021
A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy.
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Apoptosis; Biocompatible Materials; Cell Line, Tumor; Coordination Complexes; Drug Design; Fluorescent Dyes; G2 Phase Cell Cycle Checkpoints; Humans; Hyperthermia, Induced; Infrared Rays; Neoplasms; Phenazines; Photothermal Therapy; Polyethylene Glycols; Quantum Theory; Ruthenium; Spectroscopy, Near-Infrared

2022
Combination of ruthenium (II) polypyridyl complex Δ-Ru1 and Taxol enhances the anti-cancer effect on Taxol-resistant cancer cells through Caspase-1/GSDMD-mediated pyroptosis.
    Journal of inorganic biochemistry, 2022, Volume: 230

    Topics: Animals; Caspase 1; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Neoplasms; Paclitaxel; Phosphate-Binding Proteins; Pore Forming Cytotoxic Proteins; Pyroptosis; Ruthenium

2022
Systematic Study on the Cytotoxic Potency of Commonly Used Dimeric Metal Precursors in Human Cancer Cell Lines.
    ChemistryOpen, 2022, Volume: 11, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Iridium; Neoplasms; Osmium; Rhodium; Ruthenium

2022
Metal-based Complexes as Potential Anti-cancer Agents.
    Anti-cancer agents in medicinal chemistry, 2022, 08-04, Volume: 22, Issue:15

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Humans; Neoplasms; Platinum; Ruthenium

2022
In Situ Prodrug Activation by an Affibody-Ruthenium Catalyst Hybrid for HER2-Targeted Chemotherapy.
    Angewandte Chemie (International ed. in English), 2022, 06-27, Volume: 61, Issue:26

    Topics: Catalysis; Humans; Neoplasms; Prodrugs; Ruthenium

2022
Pharmacological assessment of Ru(II) complex with GidA protein- A novel topoisomerase II inhibitor towards cancer therapeutics.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:9

    Topics: DNA Topoisomerases, Type II; Humans; Molecular Docking Simulation; Neoplasms; Ruthenium; Staphylococcal Protein A; Topoisomerase II Inhibitors

2023
NIR-II Emissive Ru(II) Metallacycle Assisting Fluorescence Imaging and Cancer Therapy.
    Small (Weinheim an der Bergstrasse, Germany), 2022, Volume: 18, Issue:23

    Topics: Cisplatin; Neoplasms; Optical Imaging; Phototherapy; Ruthenium; Theranostic Nanomedicine

2022
CORM-3 induces DNA damage through Ru(II) binding to DNA.
    The Biochemical journal, 2022, 07-15, Volume: 479, Issue:13

    Topics: Antineoplastic Agents; DNA; DNA Damage; Humans; Neoplasms; Ruthenium

2022
Chiral Ru
    Angewandte Chemie (International ed. in English), 2022, 08-15, Volume: 61, Issue:33

    Topics: Animals; Antineoplastic Agents; Cisplatin; Coordination Complexes; DNA; G-Quadruplexes; Mice; Neoplasms; Ruthenium; Telomerase; Telomere

2022
Ru(II) photocages enable precise control over enzyme activity with red light.
    Nature communications, 2022, 06-25, Volume: 13, Issue:1

    Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Neoplasms; Ruthenium

2022
Impact of Polypyridyl Ru Complexes on Angiogenesis-Contribution to Their Antimetastatic Activity.
    International journal of molecular sciences, 2022, Jul-12, Volume: 23, Issue:14

    Topics: 2,2'-Dipyridyl; Coordination Complexes; Endothelial Cells; Humans; Ligands; Neoplasms; Phenanthrolines; Ruthenium

2022
Rationally designed Ru(II) metallacycles with tunable imidazole ligands for synergistical chemo-phototherapy of cancer.
    Chemical communications (Cambridge, England), 2022, Aug-11, Volume: 58, Issue:65

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Imidazoles; Ligands; Neoplasms; Phototherapy; Ruthenium

2022
Inhibition of Metastasis by Polypyridyl Ru(II) Complexes through Modification of Cancer Cell Adhesion -
    Journal of medicinal chemistry, 2022, 08-11, Volume: 65, Issue:15

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Cell Adhesion; Coordination Complexes; Humans; Ligands; Neoplasms; Ruthenium

2022
Ruthenium(II) Polypyridyl Complexes Containing Simple Dioxo Ligands: a Structure-Activity Relationship Study Shows the Importance of the Charge.
    Chembiochem : a European journal of chemical biology, 2022, 10-06, Volume: 23, Issue:19

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Coordination Complexes; Humans; Ligands; Malonates; Neoplasms; Oxalates; Platinum; Ruthenium; Structure-Activity Relationship

2022
Single laser activated photothermal/photodynamic dual-modal cancer phototherapy by using ROS-responsive targeting flower-like ruthenium nanoparticles.
    Journal of materials chemistry. B, 2022, 10-05, Volume: 10, Issue:38

    Topics: Humans; Lasers; Nanoparticles; Neoplasms; Oxides; Photochemotherapy; Phototherapy; Reactive Oxygen Species; Ruthenium

2022
New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway.
    European journal of medicinal chemistry, 2022, Dec-05, Volume: 243

    Topics: Aminosalicylic Acid; Amobarbital; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coordination Complexes; Humans; Neoplasms; Phosphorus; Ruthenium; Salicylic Acid

2022
A Lock-and-Kill Anticancer Photoactivated Chemotherapy Agent
    Photochemistry and photobiology, 2023, Volume: 99, Issue:2

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Neoplasms; Prodrugs; Ruthenium

2023
Synthesis and Characterization of New Ruthenium (II) Complexes of Stoichiometry [Ru(
    Molecules (Basel, Switzerland), 2022, Oct-26, Volume: 27, Issue:21

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; HeLa Cells; Humans; Neoplasms; Ruthenium

2022
Towards Selective Delivery of a Ruthenium(II) Polypyridyl Complex-Containing Bombesin Conjugate into Cancer Cells.
    Chembiochem : a European journal of chemical biology, 2023, 02-14, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Bombesin; Coordination Complexes; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium

2023
Dual drug delivery system of RAPTA-C and paclitaxel based on fructose coated nanoparticles for metastatic cancer treatment.
    Biochemical and biophysical research communications, 2023, 01-15, Volume: 640

    Topics: Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Fructose; Humans; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Polymers; Ruthenium; Tissue Distribution

2023
Shine, Shine, Ruthenium Caged Drug.
    Photochemistry and photobiology, 2023, Volume: 99, Issue:2

    Topics: Antineoplastic Agents; Humans; Neoplasms; Pharmaceutical Preparations; Ruthenium

2023
Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.
    International journal of molecular sciences, 2022, Dec-29, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Coordination Complexes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ferric Compounds; Ferrous Compounds; Humans; Ions; Ligands; Neoplasms; Organometallic Compounds; Proline; Ruthenium; Solubility; Water

2022
Cyclometalated Ru(II)-NHC complexes with phenanthroline ligands induce apoptosis mediated by mitochondria and endoplasmic reticulum stress in cancer cells.
    Dalton transactions (Cambridge, England : 2003), 2023, Feb-07, Volume: 52, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Coordination Complexes; Endoplasmic Reticulum Stress; HeLa Cells; Humans; Ligands; Mitochondria; Neoplasms; Phenanthrolines; Ruthenium

2023
A Near-Infrared Light-Activated Photocage Based on a Ruthenium Complex for Cancer Phototherapy.
    Angewandte Chemie (International ed. in English), 2023, 06-12, Volume: 62, Issue:24

    Topics: Humans; Nanoparticles; Neoplasms; Photochemotherapy; Phototherapy; Polymers; Ruthenium

2023
Anticancer Screening of Ru(II) Photoredox Catalysts at Single Cancer Cell Level.
    Chemistry, an Asian journal, 2023, May-02, Volume: 18, Issue:9

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Early Detection of Cancer; Humans; Neoplasms; Ruthenium

2023
Mechanistic Studies of Arene-Ruthenium(II) Complexes with Carbothioamidopyrazoles as Alternative Cancer Drugs.
    Molecules (Basel, Switzerland), 2023, May-08, Volume: 28, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Neoplasms; Reactive Oxygen Species; Ruthenium

2023
Lipid-coated ruthenium dendrimer conjugated with doxorubicin in anti-cancer drug delivery: Introducing protocols.
    Colloids and surfaces. B, Biointerfaces, 2023, Volume: 227

    Topics: Antineoplastic Agents; Dendrimers; Doxorubicin; Drug Carriers; Drug Delivery Systems; Humans; Lipids; Liposomes; Neoplasms; Ruthenium

2023
Ru(II)-
    Inorganic chemistry, 2023, Jul-31, Volume: 62, Issue:30

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coordination Complexes; Cymenes; Ligands; Mice; Neoplasms; Ruthenium

2023
Synthesis, characterization, molecular docking, RNA-sequence and anticancer efficacy evaluation in vitro of ruthenium(II) complexes on B16 cells.
    Journal of inorganic biochemistry, 2023, Volume: 247

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coordination Complexes; Humans; Molecular Docking Simulation; Neoplasms; Phenanthrolines; Reactive Oxygen Species; RNA; Ruthenium

2023
Phototoxicity of Tridentate Ru(II) Polypyridyl Complex with Expanded Bite Angles toward Mammalian Cells and Multicellular Tumor Spheroids.
    Inorganic chemistry, 2023, Aug-14, Volume: 62, Issue:32

    Topics: Animals; CHO Cells; Coordination Complexes; Cricetinae; Cricetulus; Humans; Ligands; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium

2023
Ru(II)-Cyanine Complexes as Promising Photodynamic Photosensitizers for the Treatment of Hypoxic Tumours with Highly Penetrating 770 nm Near-Infrared Light.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2023, Nov-02, Volume: 29, Issue:61

    Topics: Coloring Agents; Coordination Complexes; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium

2023
    Inorganic chemistry, 2023, Sep-25, Volume: 62, Issue:38

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Ligands; Maleimides; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium; Serum Albumin

2023
Potential anticancer agent for selective damage to mitochondria or lysosomes: Naphthalimide-modified fluorescent biomarker half-sandwich iridium (III) and ruthenium (II) complexes.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Iridium; Lysosomes; Membrane Potential, Mitochondrial; Mitochondria; Naphthalimides; Neoplasms; Ruthenium

2019
Antitumor activity of organoruthenium complexes with chelate aromatic ligands, derived from 1,10-phenantroline: Synthesis and biological activity.
    Journal of inorganic biochemistry, 2020, Volume: 202

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cisplatin; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Neoplasms; Organometallic Compounds; Phenanthrolines; Ruthenium; Tumor Cells, Cultured

2020
New ruthenium polypyridyl complexes functionalized with fluorine atom or furan: Synthesis, DNA-binding, cytotoxicity and antitumor mechanism studies.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Feb-15, Volume: 227

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Cycle Checkpoints; Coordination Complexes; DNA; Furans; Halogenation; Humans; Intercalating Agents; Membrane Potential, Mitochondrial; Neoplasms; Pyridines; Reactive Oxygen Species; Ruthenium

2020
Targeted and NIR light-controlled delivery of nitric oxide combined with a platinum(iv) prodrug for enhanced anticancer therapy.
    Journal of materials chemistry. B, 2019, 03-21, Volume: 7, Issue:11

    Topics: Drug Delivery Systems; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; MCF-7 Cells; Nanoparticles; Neoplasms; Nitric Oxide; Phototherapy; Platinum Compounds; Prodrugs; Quantum Dots; Ruthenium

2019
Boosting two-photon photodynamic therapy with mitochondria-targeting ruthenium-glucose conjugates.
    Chemical communications (Cambridge, England), 2020, May-28, Volume: 56, Issue:43

    Topics: Animals; Cell Line; Cell Survival; Glucose; Humans; Light; Mice, Inbred BALB C; Mitochondria; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium; Tumor Burden

2020
Anticancer Ruthenium Complexes with HDAC Isoform Selectivity.
    Molecules (Basel, Switzerland), 2020, May-21, Volume: 25, Issue:10

    Topics: Cell Proliferation; Coordination Complexes; HeLa Cells; Histone Deacetylase 1; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Neoplasms; Protein Conformation; Protein Isoforms; Ruthenium; Ruthenium Compounds

2020
Luminescent anticancer Ru(II)-arenebipyridine and phenanthroline complexes: Synthesis, characterization, DFT studies, biological interactions and cellular imaging application.
    Journal of inorganic biochemistry, 2020, Volume: 208

    Topics: Antineoplastic Agents; Coordination Complexes; DNA; HEK293 Cells; HeLa Cells; Humans; Luminescent Measurements; MCF-7 Cells; Neoplasms; Phenanthrolines; Pyridines; Ruthenium

2020
Development of four ruthenium polypyridyl complexes as antitumor agents: Design, biological evaluation and mechanism investigation.
    Journal of inorganic biochemistry, 2020, Volume: 208

    Topics: A549 Cells; Antineoplastic Agents; Coordination Complexes; Humans; Neoplasms; Pyridines; Ruthenium

2020
A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status.
    Journal of experimental & clinical cancer research : CR, 2020, Jun-30, Volume: 39, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Curcumin; Gene Expression Regulation, Neoplastic; Humans; Mutation; Neoplasms; NF-E2-Related Factor 2; Ruthenium; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2020
Two-photon photodynamic ablation of tumour cells using an RGD peptide-conjugated ruthenium(ii) photosensitiser.
    Chemical communications (Cambridge, England), 2020, Oct-25, Volume: 56, Issue:83

    Topics: Animals; Cell Line, Tumor; Coordination Complexes; Humans; Mice; Mice, Nude; Mitochondria; Neoplasms; Oligopeptides; Photochemotherapy; Photons; Photosensitizing Agents; Reactive Oxygen Species; Ruthenium; Transplantation, Heterologous

2020
Photoinduced synergistic cytotoxicity towards cancer cells
    Dalton transactions (Cambridge, England : 2003), 2020, Oct-20, Volume: 49, Issue:40

    Topics: Antineoplastic Agents; Cell Membrane Permeability; Cell Survival; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Ligands; MCF-7 Cells; Neoplasms; Phenanthrolines; Photochemotherapy; Pyridines; Ruthenium; Singlet Oxygen; Structure-Activity Relationship

2020
Bis(bipyridine)ruthenium(II) Ferrocenyl β-Diketonate Complexes: Exhibiting Nanomolar Potency against Human Cancer Cell Lines.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2021, Feb-19, Volume: 27, Issue:11

    Topics: Antineoplastic Agents; Cell Line, Tumor; Comet Assay; Coordination Complexes; Humans; Microbial Sensitivity Tests; Neoplasms; Ruthenium

2021
Lapachol in the Design of a New Ruthenium(II)-Diphosphine Complex as a Promising Anticancer Metallodrug.
    Journal of inorganic biochemistry, 2021, Volume: 214

    Topics: A549 Cells; Antineoplastic Agents; Coordination Complexes; Humans; MCF-7 Cells; Naphthoquinones; Neoplasms; Phosphines; Ruthenium

2021
Polymeric Encapsulation of a Ruthenium Polypyridine Complex for Tumor Targeted One- and Two-Photon Photodynamic Therapy.
    ACS applied materials & interfaces, 2020, Dec-09, Volume: 12, Issue:49

    Topics: Animals; Cell Line, Tumor; Cell Survival; Coordination Complexes; Female; Humans; Light; Mice; Mice, Nude; Neoplasms; Photochemotherapy; Photons; Photosensitizing Agents; Polymers; Pyridines; Ruthenium; Singlet Oxygen; Spheroids, Cellular; Tissue Distribution; Transplantation, Heterologous

2020
Ruthenium(II) 1,4,7-trithiacyclononane complexes of curcumin and bisdemethoxycurcumin: Synthesis, characterization, and biological activity.
    Journal of inorganic biochemistry, 2021, Volume: 218

    Topics: Alkanes; Antineoplastic Agents; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Curcumin; Humans; Models, Molecular; Neoplasms; Ruthenium; Sulfur Compounds; Tumor Cells, Cultured

2021
Arene Ruthenium(II) Complexes Bearing the κ-
    Molecules (Basel, Switzerland), 2021, Mar-25, Volume: 26, Issue:7

    Topics: Antineoplastic Agents; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Neoplasms; Ruthenium

2021
Polymeric Encapsulation of a Ru(II)-Based Photosensitizer for Folate-Targeted Photodynamic Therapy of Drug Resistant Cancers.
    Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8

    Topics: Cell Culture Techniques; Cell Line; Cell Survival; Coordination Complexes; Drug Resistance, Neoplasm; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Light; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polymers; Ruthenium; Singlet Oxygen; Spheroids, Cellular

2021
A highly potent ruthenium(II)-sonosensitizer and sonocatalyst for in vivo sonotherapy.
    Nature communications, 2021, 08-18, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Humans; Mice; Mice, Inbred BALB C; NAD; Neoplasms; Oxidation-Reduction; Porphyrins; Ruthenium; Singlet Oxygen; Ultrasonic Therapy; Ultrasonic Waves

2021
Ruthenium complexes with phenylterpyridine derivatives target cell membrane and trigger death receptors-mediated apoptosis in cancer cells.
    Biomaterials, 2017, Volume: 129

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cisplatin; Coordination Complexes; DNA Damage; Endocytosis; Humans; Mice, Nude; Models, Biological; Neoplasms; Phosphorylation; Pyridines; Reactive Oxygen Species; Receptors, Death Domain; Receptors, Transferrin; Ruthenium; Spheroids, Cellular; Tissue Distribution; Tumor Suppressor Protein p53

2017
Metabolic Profiling of Cells in Response to Drug Treatment using
    Chimia, 2017, 03-29, Volume: 71, Issue:3

    Topics: Amino Acids; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Coordination Complexes; Drug Resistance, Neoplasm; HEK293 Cells; Humans; Magnetic Resonance Spectroscopy; Metabolomics; Neoplasms; Principal Component Analysis; Ruthenium

2017
Impact of aromaticity on anticancer activity of polypyridyl ruthenium(II) complexes: synthesis, structure, DNA/protein binding, lipophilicity and anticancer activity.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2017, Volume: 22, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Coordination Complexes; DNA; Humans; Models, Molecular; Neoplasms; Pyridines; Ruthenium; Serum Albumin, Bovine

2017
Selective Ru(II)/lawsone complexes inhibiting tumor cell growth by apoptosis.
    Journal of inorganic biochemistry, 2017, Volume: 176

    Topics: A549 Cells; Antineoplastic Agents; Coordination Complexes; G1 Phase; Humans; Naphthoquinones; Neoplasms; Ruthenium; S Phase

2017
Pompon-like RuNPs-Based Theranostic Nanocarrier System with Stable Photoacoustic Imaging Characteristic for Accurate Tumor Detection and Efficient Phototherapy Guidance.
    ACS applied materials & interfaces, 2017, Oct-04, Volume: 9, Issue:39

    Topics: Humans; Metal Nanoparticles; Neoplasms; Photoacoustic Techniques; Phototherapy; Ruthenium; Theranostic Nanomedicine

2017
Amberlite IR-120 (H) mediated "on water" synthesis of fluorescent Ruthenium(II)-arene 8-hydroxyquinoline complexes for cancer therapy and live cell imaging.
    Journal of photochemistry and photobiology. B, Biology, 2018, Volume: 178

    Topics: Antineoplastic Agents; Binding Sites; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Coordination Complexes; DNA; HeLa Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Neoplasms; Oxyquinoline; Polystyrenes; Protein Binding; Ruthenium; Serum Albumin, Bovine; Structure-Activity Relationship; Water

2018
Anticancer metallodrugs: where is the next cisplatin?
    Future medicinal chemistry, 2018, 03-01, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Endoplasmic Reticulum Stress; Humans; Neoplasms; Platinum; Prodrugs; Ruthenium

2018
New Ru(ii) complex for dual photochemotherapy: release of cathepsin K inhibitor and
    Dalton transactions (Cambridge, England : 2003), 2018, Aug-29, Volume: 47, Issue:34

    Topics: Acetonitriles; Cathepsin K; Coordination Complexes; Enzyme Inhibitors; Humans; Ligands; Methanol; Neoplasms; Phenazines; Photochemotherapy; Photosensitizing Agents; Plasmids; Pyridines; Ruthenium; Singlet Oxygen; Water

2018
Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines.
    Journal of inorganic biochemistry, 2018, Volume: 186

    Topics: A549 Cells; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Humans; Neoplasms; Organometallic Compounds; Oxyquinoline; Ruthenium

2018
Induction of the Endoplasmic Reticulum Stress Pathway by Highly Cytotoxic Organoruthenium Schiff-Base Complexes.
    Molecular pharmaceutics, 2018, 08-06, Volume: 15, Issue:8

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Endoplasmic Reticulum Stress; Humans; Molecular Structure; Neoplasms; Organometallic Compounds; Quinolines; Reactive Oxygen Species; Ruthenium; Schiff Bases; Structure-Activity Relationship

2018
Fluorescent organometallic rhodium(I) and ruthenium(II) metallodrugs with 4-ethylthio-1,8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorescent Dyes; G-Quadruplexes; Humans; Intercalating Agents; Ligands; Naphthalimides; Neoplasms; Organometallic Compounds; Rhodium; Ruthenium

2018
A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3.
    Redox biology, 2018, Volume: 18

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Carbon Monoxide; Cell Line, Tumor; Cell Survival; Escherichia coli; Escherichia coli Infections; Humans; Neoplasms; Organometallic Compounds; Ruthenium

2018
Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Humans; Hydroxyquinolines; Ligands; Models, Molecular; Neoplasms; Protein Biosynthesis; Ruthenium; Structure-Activity Relationship; Transcription, Genetic

2018
Mechanistic Investigation into DNA Modification by a Ru
    Chembiochem : a European journal of chemical biology, 2018, 10-18, Volume: 19, Issue:20

    Topics: Antineoplastic Agents; DNA; Humans; Light; Neoplasms; Oxygen; Photochemotherapy; Photolysis; Photosensitizing Agents; Rhodium; Ruthenium; Tumor Hypoxia

2018
Photodamaging of Mitochondrial DNA to Overcome Cisplatin Resistance by a Ru
    Chemistry (Weinheim an der Bergstrasse, Germany), 2018, Dec-17, Volume: 24, Issue:71

    Topics: A549 Cells; Antineoplastic Agents; Cisplatin; Coordination Complexes; DNA Damage; DNA, Mitochondrial; HeLa Cells; Humans; Neoplasms; Organoplatinum Compounds; Phenanthrolines; Photochemotherapy; Photosensitizing Agents; Pyrimidines; Ruthenium

2018
Designing luminescent ruthenium prodrug for precise cancer therapy and rapid clinical diagnosis.
    Biomaterials, 2019, Volume: 192

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Luminescent Agents; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Optical Imaging; Prodrugs; Ruthenium; Theranostic Nanomedicine; Tumor Microenvironment

2019
Mitochondria targeted and NADH triggered photodynamic activity of chloromethyl modified Ru(ii) complexes under hypoxic conditions.
    Chemical communications (Cambridge, England), 2019, Feb-26, Volume: 55, Issue:18

    Topics: Apoptosis; Cell Hypoxia; Cell Line, Tumor; Coordination Complexes; DNA Cleavage; Humans; Light; Membrane Potential, Mitochondrial; Mitochondria; NAD; Neoplasms; Photochemotherapy; Ruthenium

2019
Self-assembled ruthenium (II) metallacycles and metallacages with imidazole-based ligands and their in vitro anticancer activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 03-05, Volume: 116, Issue:10

    Topics: A549 Cells; Antineoplastic Agents; Coordination Complexes; HCT116 Cells; HeLa Cells; Hep G2 Cells; Humans; Imidazoles; MCF-7 Cells; Neoplasms; Ruthenium

2019
A tumor-targeting Ru/polysaccharide/protein supramolecular assembly with high photodynamic therapy ability.
    Chemical communications (Cambridge, England), 2019, Mar-07, Volume: 55, Issue:21

    Topics: A549 Cells; Adamantane; beta-Cyclodextrins; Cell Line; Coordination Complexes; Drug Delivery Systems; Humans; Models, Molecular; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium; Transferrin

2019
Comparative antitumor studies of organoruthenium complexes with 8-hydroxyquinolines on 2D and 3D cell models of bone, lung and breast cancer.
    Metallomics : integrated biometal science, 2019, 03-20, Volume: 11, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Humans; Models, Biological; Neoplasms; Organometallic Compounds; Oxyquinoline; Ruthenium; Ruthenium Compounds

2019
Preparation of a Ruthenium-Complex-Functionalized Two-Photon-Excited Red Fluorescence Silicon Nanoparticle Composite for Targeted Fluorescence Imaging and Photodynamic Therapy in Vitro.
    ACS applied materials & interfaces, 2019, Apr-17, Volume: 11, Issue:15

    Topics: Animals; Cell Survival; Coordination Complexes; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Mice; Mice, Nude; Microwaves; Nanoparticles; Neoplasms; Optical Imaging; Photochemotherapy; Ruthenium; Silicon; Singlet Oxygen; Toxicity Tests; Zebrafish

2019
Ruthenium - A Non-essential Element that May Become Essential in Treating Chemoresistant Cancers.
    Chimia, 2019, Apr-24, Volume: 73, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Neoplasms; Ruthenium

2019
Receptor-Mediated and Tumor-Microenvironment Combination-Responsive Ru Nanoaggregates for Enhanced Cancer Phototheranostics.
    ACS applied materials & interfaces, 2019, May-15, Volume: 11, Issue:19

    Topics: Animals; Apoptosis; Cell Line, Tumor; Contrast Media; Doxorubicin; Drug Delivery Systems; Humans; Hyaluronic Acid; Mice; Nanoparticles; Neoplasms; Photochemotherapy; Ruthenium; Theranostic Nanomedicine; Tumor Microenvironment; Xenograft Model Antitumor Assays

2019
Serendipitous Synthesis of Five-Coordinated Half-Sandwich Aminoimine Iridium(III) and Ruthenium(II) Complexes and Their Application as Potent Anticancer Agents.
    Inorganic chemistry, 2019, May-06, Volume: 58, Issue:9

    Topics: A549 Cells; Amination; Antineoplastic Agents; Cell Survival; Coordination Complexes; Crystallography, X-Ray; HeLa Cells; Hep G2 Cells; Humans; Imines; Iridium; Models, Molecular; Neoplasms; Ruthenium

2019
Polynuclear ruthenium organometallic compounds induce DNA damage in human cells identified by the nucleotide excision repair factor XPC.
    Bioscience reports, 2019, 07-31, Volume: 39, Issue:7

    Topics: Cell Line, Tumor; Cell Proliferation; Chromatin; DNA Damage; DNA Repair; DNA-Binding Proteins; Humans; Neoplasms; Organometallic Compounds; Platinum; Ruthenium

2019
Synthesis and Characterization of an Epidermal Growth Factor Receptor-Selective Ru
    Chembiochem : a European journal of chemical biology, 2020, 02-17, Volume: 21, Issue:4

    Topics: Cell Line, Tumor; ErbB Receptors; Humans; Neoplasms; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Polycyclic Compounds; Ruthenium

2020
Microwave-assisted synthesis of arene ruthenium(II) complexes that induce S-phase arrest in cancer cells by DNA damage-mediated p53 phosphorylation.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Blotting, Western; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Cell Survival; Circular Dichroism; Crystallography, X-Ray; Cyclin A; DNA Damage; Dose-Response Relationship, Drug; Humans; Hydrocarbons, Aromatic; Microwaves; Models, Chemical; Molecular Structure; Neoplasms; Organometallic Compounds; Phosphorylation; Ruthenium; S Phase; Tumor Suppressor Protein p53

2013
Transporting and shielding photosensitisers by using water-soluble organometallic cages: a new strategy in drug delivery and photodynamic therapy.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Jun-24, Volume: 19, Issue:26

    Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Coordination Complexes; Drug Carriers; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Ruthenium; Water

2013
Metallomics for drug development: an integrated CE-ICP-MS and ICP-MS approach reveals the speciation changes for an investigational ruthenium(III) drug bound to holo-transferrin in simulated cancer cytosol.
    Metallomics : integrated biometal science, 2013, Volume: 5, Issue:8

    Topics: Antineoplastic Agents; Ascorbic Acid; Blood Proteins; Cell Proliferation; Cytosol; Drug Design; Electrophoresis, Capillary; Glutathione; Humans; Ligands; Mass Spectrometry; Neoplasms; Oxidation-Reduction; Protein Binding; Ruthenium; Time Factors; Transferrin

2013
A ruthenium(II) β-carboline complex induced p53-mediated apoptosis in cancer cells.
    Biochimie, 2013, Volume: 95, Issue:11

    Topics: Animals; Apoptosis; Carbolines; Cell Proliferation; Cytochromes c; Hep G2 Cells; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Neoplasms; Ruthenium; Signal Transduction; Tumor Suppressor Protein p53

2013
X-ray fluorescence imaging of single human cancer cells reveals that the N-heterocyclic ligands of iodinated analogues of ruthenium anticancer drugs remain coordinated after cellular uptake.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2013, Volume: 18, Issue:7

    Topics: Antineoplastic Agents; Biological Transport; Cell Adhesion; Cell Line, Tumor; Heterocyclic Compounds; Humans; Iodine; Ligands; Neoplasms; Optical Imaging; Organometallic Compounds; Quaternary Ammonium Compounds; Ruthenium; Single-Cell Analysis; X-Rays

2013
Cytotoxicity, apoptosis, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential, and Western blotting analysis of ruthenium(II) complexes.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2013, Volume: 18, Issue:8

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle Checkpoints; Cell Line, Tumor; Coordination Complexes; Humans; Membrane Potential, Mitochondrial; Neoplasms; Phenanthrolines; Phenazines; Pyridines; Reactive Oxygen Species; Ruthenium

2013
A new design for nucleolipid-based Ru(III) complexes as anticancer agents.
    Dalton transactions (Cambridge, England : 2003), 2013, Dec-28, Volume: 42, Issue:48

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Drug Design; Fatty Acids, Monounsaturated; Humans; Neoplasms; Phosphatidylcholines; Quaternary Ammonium Compounds; Ruthenium; Uridine

2013
Biological studies of chalcogenolato-bridged dinuclear half-sandwich complexes.
    Inorganic chemistry, 2013, Dec-02, Volume: 52, Issue:23

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Survival; Chalcogens; Coordination Complexes; DNA; Humans; Neoplasms; Ruthenium

2013
Interaction between 8-hydroxyquinoline ruthenium(II) complexes and basic fibroblast growth factors (bFGF): inhibiting angiogenesis and tumor growth through ERK and AKT signaling pathways.
    Metallomics : integrated biometal science, 2014, Volume: 6, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Coordination Complexes; Fibroblast Growth Factor 2; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; MAP Kinase Signaling System; Mice; Mice, SCID; Neoplasms; Oxyquinoline; Proto-Oncogene Proteins c-akt; Ruthenium; Signal Transduction

2014
Production of reactive oxygen and nitrogen species by light irradiation of a nitrosyl phthalocyanine ruthenium complex as a strategy for cancer treatment.
    Dalton transactions (Cambridge, England : 2003), 2014, Mar-14, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Indoles; Isoindoles; Light; Mice; Neoplasms; Nitric Oxide; Photochemotherapy; Pyrazines; Pyridines; Ruthenium; Singlet Oxygen

2014
Synthesis, characterization, DNA binding, light switch "on and off", docking studies and cytotoxicity, of ruthenium(II) and cobalt(III) polypyridyl complexes.
    Journal of fluorescence, 2014, Volume: 24, Issue:3

    Topics: Anti-Bacterial Agents; Bacteria; Cell Survival; Cobalt; DNA; Intercalating Agents; Light; Magnetic Resonance Spectroscopy; Neoplasms; Organometallic Compounds; Phenanthrolines; Pyridines; Ruthenium; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured

2014
Anticancer potency studies of coordination driven self-assembled arene–Ru-based metalla-bowls.
    Chembiochem : a European journal of chemical biology, 2014, Mar-21, Volume: 15, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cymenes; Gene Expression Regulation, Neoplastic; Humans; Models, Molecular; Molecular Conformation; Monoterpenes; Neoplasms; Organometallic Compounds; Pyridines; Ruthenium

2014
pH and DNA luminescence switching, DNA photocleavage and cytotoxic properties of two thiophene-containing ruthenium(II) complexes.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Proliferation; Coordination Complexes; DNA; DNA Cleavage; Humans; Hydrogen-Ion Concentration; Light; Luminescence; Molecular Structure; Neoplasms; Organometallic Compounds; Quantum Theory; Ruthenium; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured

2014
Ruthenium (II) complexes interact with human serum albumin and induce apoptosis of tumor cells.
    Biological trace element research, 2015, Volume: 163, Issue:1-2

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Neoplasms; Ruthenium; Serum Albumin

2015
Phosphorescent ruthenium complexes with a nitroimidazole unit that image oxygen fluctuation in tumor tissue.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Feb-02, Volume: 21, Issue:6

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Coordination Complexes; Energy Transfer; Female; Green Fluorescent Proteins; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Neoplasms; Nitroimidazoles; Optical Imaging; Oxygen; Ruthenium; Transplantation, Heterologous

2015
A selenium-containing ruthenium complex as a cancer radiosensitizer, rational design and the important role of ROS-mediated signalling.
    Chemical communications (Cambridge, England), 2015, Feb-14, Volume: 51, Issue:13

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; DNA Damage; Drug Design; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Molecular Structure; Neoplasms; Organometallic Compounds; Radiation-Sensitizing Agents; Reactive Oxygen Species; Ruthenium; Selenium; Signal Transduction; Structure-Activity Relationship

2015
The biological effect of the nitroimidazole derivative of a polypyridyl ruthenium complex on cancer and endothelial cells.
    Metallomics : integrated biometal science, 2015, Volume: 7, Issue:3

    Topics: Animals; Apoptosis; Cell Adhesion; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cisplatin; Coordination Complexes; Endocytosis; Endothelial Cells; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Mice; Microscopy, Fluorescence; Neoplasms; Neovascularization, Physiologic; Nitroimidazoles; Oxidative Stress; Pyridines; RNA, Messenger; Ruthenium; Subcellular Fractions; Wound Healing

2015
Modulating the Anticancer Activity of Ruthenium(II)-Arene Complexes.
    Journal of medicinal chemistry, 2015, Apr-23, Volume: 58, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Coordination Complexes; Crystallography, X-Ray; Cymenes; Humans; Models, Molecular; Monoterpenes; Neoplasms; Ruthenium

2015
Hypoxia-Sensitive Metal β-Ketoiminato Complexes Showing Induced Single-Strand DNA Breaks and Cancer Cell Death by Apoptosis.
    Journal of medicinal chemistry, 2015, Jun-25, Volume: 58, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Coordination Complexes; Crystallography, X-Ray; DNA Breaks, Single-Stranded; Humans; Hypoxia; Iridium; Models, Molecular; Neoplasms; Ruthenium

2015
Multifunctional selenium nanoparticles: Chiral selectivity of delivering MDR-siRNA for reversal of multidrug resistance and real-time biofluorescence imaging.
    Nanomedicine : nanotechnology, biology, and medicine, 2015, Volume: 11, Issue:7

    Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Gene Transfer Techniques; Humans; Nanoparticles; Neoplasms; RNA, Small Interfering; Ruthenium; Selenium

2015
Design, synthesis and characterisation of new chimeric ruthenium(II)-gold(I) complexes as improved cytotoxic agents.
    Dalton transactions (Cambridge, England : 2003), 2015, Jun-28, Volume: 44, Issue:24

    Topics: Antineoplastic Agents; Cathepsin B; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Cymenes; DNA; Gold; Humans; Models, Molecular; Monoterpenes; Neoplasms; Ruthenium

2015
1H HR-MAS NMR Based Metabolic Profiling of Cells in Response to Treatment with a Hexacationic Ruthenium Metallaprism as Potential Anticancer Drug.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Magnetic Resonance Spectroscopy; Metabolome; Neoplasms; Organometallic Compounds; Ruthenium

2015
Dual-targeting organometallic ruthenium(II) anticancer complexes bearing EGFR-inhibiting 4-anilinoquinazoline ligands.
    Dalton transactions (Cambridge, England : 2003), 2015, Aug-07, Volume: 44, Issue:29

    Topics: Aniline Compounds; Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; HeLa Cells; Humans; Models, Molecular; Neoplasms; Organometallic Compounds; Quinazolines; Ruthenium

2015
Receptor selective ruthenium-somatostatin photosensitizer for cancer targeted photodynamic applications.
    Chemical communications (Cambridge, England), 2015, Aug-14, Volume: 51, Issue:63

    Topics: Cell Line, Tumor; Cell Survival; Coordination Complexes; Endocytosis; Humans; Microscopy, Confocal; Neoplasms; Photochemotherapy; Photosensitizing Agents; Receptors, Somatostatin; Ruthenium; Singlet Oxygen; Somatostatin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2015
Simultaneous realization of Hg(2+) sensing, magnetic resonance imaging and upconversion luminescence in vitro and in vivo bioimaging based on hollow mesoporous silica coated UCNPs and ruthenium complex.
    Nanoscale, 2015, Sep-07, Volume: 7, Issue:33

    Topics: Animals; Cell Line, Tumor; Cell Survival; Coordination Complexes; HeLa Cells; Humans; Ions; Magnetic Resonance Imaging; Mercury; Mice; Mice, Nude; Microscopy, Confocal; Nanoparticles; Neoplasms; Polyethyleneimine; Porosity; Radiography; Ruthenium; Silicon Dioxide; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Transplantation, Heterologous

2015
Labile ruthenium(ii) complexes with extended phenyl-substituted terpyridyl ligands: synthesis, aquation and anticancer evaluation.
    Dalton transactions (Cambridge, England : 2003), 2015, Sep-21, Volume: 44, Issue:35

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Chlorides; HeLa Cells; Humans; Ligands; Neoplasms; Organometallic Compounds; Ruthenium; Water

2015
Effects of the ruthenium-based drug NAMI-A on the roles played by TGF-β1 in the metastatic process.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2015, Volume: 20, Issue:7

    Topics: Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Humans; Molecular Structure; Neoplasm Metastasis; Neoplasms; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Transforming Growth Factor beta1

2015
Synthesis, Anticancer Activity, and Genome Profiling of Thiazolo Arene Ruthenium Complexes.
    Journal of medicinal chemistry, 2015, Nov-12, Volume: 58, Issue:21

    Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cymenes; Female; Gene Expression Regulation, Neoplastic; Humans; Models, Molecular; Monoterpenes; Neoplasms; Ovarian Neoplasms; Ruthenium; Thiazoles; Transcriptome

2015
Ru(II)-polypyridyl surface functionalised gold nanoparticles as DNA targeting supramolecular structures and luminescent cellular imaging agents.
    Nanoscale, 2016, Jan-07, Volume: 8, Issue:1

    Topics: DNA, Neoplasm; Gold; HeLa Cells; Humans; Metal Nanoparticles; Neoplasms; Optical Imaging; Ruthenium

2016
Ruthenium-Containing Block Copolymer Assemblies: Red-Light-Responsive Metallopolymers with Tunable Nanostructures for Enhanced Cellular Uptake and Anticancer Phototherapy.
    Advanced healthcare materials, 2016, Feb-18, Volume: 5, Issue:4

    Topics: Cell Survival; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Light; Micelles; Molecular Weight; Nanostructures; Neoplasms; Phototherapy; Polyethylene Glycols; Polymers; Prodrugs; Ruthenium

2016
Ruthenium(III) Complexes of Heterocyclic Tridentate (ONN) Schiff Base: Synthesis, Characterization and its Biological Properties as an Antiradical and Antiproliferative Agent.
    International journal of molecular sciences, 2016, Jan-04, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Benzothiazoles; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Free Radical Scavengers; Heterocyclic Compounds; Humans; Ligands; Neoplasms; Picrates; Ruthenium; Schiff Bases; Sulfonic Acids

2016
Protein-binding, cytotoxicity in vitro and cell cycle arrest of ruthenium(II) polypyridyl complexes.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, May-15, Volume: 161

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Coordination Complexes; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Neoplasms; Reactive Oxygen Species; Ruthenium

2016
Editorial: Anticancer Ruthenium Complexes in Drug Discovery and Medicinal Chemistry.
    Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:10

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Coordination Complexes; Drug Discovery; Humans; Neoplasms; Ruthenium

2016
Thiol-Activated HNO Release from a Ruthenium Antiangiogenesis Complex and HIF-1α Inhibition for Cancer Therapy.
    ACS chemical biology, 2016, 07-15, Volume: 11, Issue:7

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Nitric Oxide; Nitrogen Oxides; Ruthenium; Sulfhydryl Compounds

2016
Topoisomerase IIα poisoning and DNA double-strand breaking by chiral ruthenium(ii) complexes containing 2-furanyl-imidazo[4,5-f][1,10]phenanthroline derivatives.
    Dalton transactions (Cambridge, England : 2003), 2016, Jun-28, Volume: 45, Issue:26

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; Humans; Molecular Docking Simulation; Neoplasms; Phenanthrolines; Ruthenium; Topoisomerase II Inhibitors

2016
In vitro and in vivo antitumor activity of a novel carbonyl ruthenium compound, the ct-[RuCl(CO)(dppb)(bipy)]PF-6[dppb=1,4-bis(diphenylphosphine)butane and bipy=2,2'-bipyridine].
    Journal of inorganic biochemistry, 2016, Volume: 164

    Topics: Animals; Antineoplastic Agents; Cattle; Coordination Complexes; Cricetinae; DNA; Female; HeLa Cells; Hep G2 Cells; Humans; MCF-7 Cells; Mice; Neoplasms; Ruthenium; Serum Albumin, Bovine

2016
Anti-tumor activity and mechanism of apoptosis of A549 induced by ruthenium complex.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2016, Volume: 21, Issue:8

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Binding, Competitive; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Circular Dichroism; Coordination Complexes; DNA; Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; G-Quadruplexes; HeLa Cells; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Neoplasms; Reactive Oxygen Species; Ruthenium; Spectrophotometry; Time Factors

2016
Clioquinol-ruthenium complex impairs tumour cell invasion by inhibiting cathepsin B activity.
    Dalton transactions (Cambridge, England : 2003), 2016, Nov-14, Volume: 45, Issue:42

    Topics: Antineoplastic Agents; Cathepsin B; Cell Line, Tumor; Clioquinol; Cymenes; Enzyme Inhibitors; Humans; Monoterpenes; Neoplasm Invasiveness; Neoplasms; Organometallic Compounds; Ruthenium

2016
An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo.
    Advanced materials (Deerfield Beach, Fla.), 2017, Volume: 29, Issue:6

    Topics: Animals; Light; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Phototherapy; Ruthenium

2017
A ruthenium anticancer compound interacts with histones and impacts differently on epigenetic and death pathways compared to cisplatin.
    Oncotarget, 2017, Jan-10, Volume: 8, Issue:2

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; HCT116 Cells; Histones; Humans; Neoplasms; Organometallic Compounds; Ruthenium

2017
Ruthenium(II) Complex Incorporated UiO-67 Metal-Organic Framework Nanoparticles for Enhanced Two-Photon Fluorescence Imaging and Photodynamic Cancer Therapy.
    ACS applied materials & interfaces, 2017, Feb-22, Volume: 9, Issue:7

    Topics: Fluorescence; Humans; Metal Nanoparticles; Metal-Organic Frameworks; Neoplasms; Ruthenium

2017
Long Blood Residence and Large Tumor Uptake of Ruthenium Sulfide Nanoclusters for Highly Efficient Cancer Photothermal Therapy.
    Scientific reports, 2017, 01-31, Volume: 7

    Topics: Animals; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Humans; Hyperthermia, Induced; Metal Nanoparticles; Mice; Neoplasms; Phototherapy; Polyethylene Glycols; Ruthenium; Tissue Distribution; Xenograft Model Antitumor Assays

2017
Preface.
    Anti-cancer agents in medicinal chemistry, 2017, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Coordination Complexes; Drug Discovery; Heterocyclic Compounds; Humans; Neoplasms; Ruthenium

2017
Sensitization of ruthenium nitrosyls to visible light via direct coordination of the dye resorufin: trackable NO donors for light-triggered NO delivery to cellular targets.
    Journal of the American Chemical Society, 2008, Jul-09, Volume: 130, Issue:27

    Topics: Cell Line, Tumor; Fluorescent Dyes; Humans; Light; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Organometallic Compounds; Oxazines; Photochemotherapy; Photolysis; Ruthenium; Skin Neoplasms

2008
Cytotoxicity, cellular uptake, and DNA interactions of new monodentate ruthenium(II) complexes containing terphenyl arenes.
    Journal of medicinal chemistry, 2008, Sep-11, Volume: 51, Issue:17

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; DNA; DNA, Superhelical; Guanine; Humans; Neoplasms; Nucleic Acid Denaturation; Organometallic Compounds; Ruthenium; Spectrum Analysis; Structure-Activity Relationship; Terphenyl Compounds

2008
Combined arene ruthenium porphyrins as chemotherapeutics and photosensitizers for cancer therapy.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2009, Volume: 14, Issue:1

    Topics: Antineoplastic Agents; Calixarenes; Cell Proliferation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Screening Assays, Antitumor; Humans; Light; Metalloporphyrins; Molecular Structure; Neoplasms; Photosensitizing Agents; Ruthenium; Time Factors; Tumor Cells, Cultured

2009
Metal complexes as photochemical nitric oxide precursors: potential applications in the treatment of tumors.
    Dalton transactions (Cambridge, England : 2003), 2009, Dec-28, Issue:48

    Topics: Chromium; Coordination Complexes; Energy Transfer; Fluorescence Resonance Energy Transfer; Humans; Iron; Neoplasms; Nitric Oxide; Nitroso Compounds; Photochemical Processes; Quantum Dots; Radiation-Sensitizing Agents; Ruthenium

2009
The Midas touch in cancer chemotherapy: from platinum- to gold-dithiocarbamato complexes.
    Dalton transactions (Cambridge, England : 2003), 2009, Dec-28, Issue:48

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Gold; Humans; Mice; Neoplasms; Platinum; Ruthenium; Thiocarbamates

2009
Ruthenium(II)-arene complexes with functionalized pyridines: synthesis, characterization and cytotoxic activity.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Neoplasms; Organometallic Compounds; Ruthenium

2010
Use of perfluorinated phosphines to provide thermomorphic anticancer complexes for heat-based tumor targeting.
    Inorganic chemistry, 2010, Mar-01, Volume: 49, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Halogenation; Hot Temperature; Humans; Inhibitory Concentration 50; Neoplasms; Organometallic Compounds; Phosphines; Ruthenium; Solubility; Water

2010
Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using ruthenium nanoparticle-based ultrasensitive chemiluminescence detection.
    Chemical communications (Cambridge, England), 2010, Sep-07, Volume: 46, Issue:33

    Topics: Biosensing Techniques; Cell Line, Tumor; Dendrimers; DNA; Electrophoresis, Agar Gel; Humans; Luminescent Agents; Luminescent Measurements; Metal Nanoparticles; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Neoplasms; Ruthenium; Surface Properties

2010
Noncovalent DNA-binding metallo-supramolecular cylinders prevent DNA transactions in vitro.
    Angewandte Chemie (International ed. in English), 2010, Nov-15, Volume: 49, Issue:47

    Topics: Coordination Complexes; DNA; DNA Replication; Humans; Iron; Ligands; Neoplasms; Ruthenium; Taq Polymerase

2010
Dye-tethered ruthenium nitrosyls containing planar dicarboxamide tetradentate N4 ligands: effects of in-plane ligand twist on NO photolability.
    Inorganic chemistry, 2011, Jan-03, Volume: 50, Issue:1

    Topics: Benzene; Crystallography, X-Ray; Fluorescent Dyes; Ligands; Light; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Nitric Oxide; Nitroso Compounds; Oxazines; Photochemistry; Photolysis; Pyridines; Ruthenium

2011
Antiproliferative activity of dmoPTA-Ru(II) complexes against human solid tumor cells.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Neoplasms; Ruthenium

2011
Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex.
    Journal of the American Chemical Society, 2011, Sep-07, Volume: 133, Issue:35

    Topics: Antineoplastic Agents; Binding Sites; DNA; Drug Delivery Systems; Humans; Neoplasms; Octreotide; Oligopeptides; Organometallic Compounds; Photochemical Processes; Ruthenium

2011
Synthesis and in vitro anticancer activity of ruthenium-cymene complexes with cyclohexyl-functionalized ethylenediamine-N,N'-diacetate-type ligands.
    ChemMedChem, 2011, Oct-04, Volume: 6, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coordination Complexes; Ethylenediamines; Humans; Ligands; Neoplasms; Ruthenium; Stereoisomerism; Structure-Activity Relationship

2011
From catalysts to bioactive organometallics: do Grubbs catalysts trigger biological effects?
    ChemMedChem, 2011, Dec-09, Volume: 6, Issue:12

    Topics: Antineoplastic Agents; Catalysis; Cell Line, Tumor; Cell Survival; Coordination Complexes; Drug Design; Enzyme Inhibitors; Enzymes; Humans; Neoplasms; Organometallic Compounds; Ruthenium

2011
Synthesis of glycoconjugate carbonic anhydrase inhibitors by ruthenium-catalysed azide-alkyne 1,3-dipolar cycloaddition.
    Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20

    Topics: Alkynes; Antineoplastic Agents; Azides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Cell Line, Tumor; Cyclization; Glycoconjugates; Humans; Neoplasms; Ruthenium

2011
Efficient oxidation of cysteine and glutathione catalyzed by a dinuclear areneruthenium trithiolato anticancer complex.
    Inorganic chemistry, 2011, Nov-07, Volume: 50, Issue:21

    Topics: Antineoplastic Agents; Catalysis; Cysteine; Disulfides; Glutathione; Magnetic Resonance Spectroscopy; Neoplasms; Organometallic Compounds; Oxidation-Reduction; Ruthenium

2011
Efficient photodynamic therapy of cancer using chemotherapeutic porphyrin-ruthenium metalla-cubes.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Cations; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Light; Melanoma; Metals; Models, Chemical; Neoplasms; Ovarian Neoplasms; Photochemistry; Photochemotherapy; Photosensitizing Agents; Porphyrins; Ruthenium; Time Factors

2012
Ruthenium-based complex nanocarriers for cancer therapy.
    Biomaterials, 2012, Volume: 33, Issue:14

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Stability; Humans; Liposomes; Materials Testing; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Organometallic Compounds; Rats; Ruthenium

2012
Spectral characteristics, DNA-binding and cytotoxicity of two functional Ru(II) mixed-ligand complexes.
    Dalton transactions (Cambridge, England : 2003), 2012, Apr-21, Volume: 41, Issue:15

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cattle; Cell Survival; Coordination Complexes; DNA; HeLa Cells; Hep G2 Cells; Humans; Ligands; Models, Molecular; Neoplasms; Phenanthrolines; Ruthenium; Spectrum Analysis

2012
Strained ruthenium complexes are potent light-activated anticancer agents.
    Journal of the American Chemical Society, 2012, May-23, Volume: 134, Issue:20

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; DNA; Humans; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium

2012
Ruthenium complexes containing 2,6-bis(benzimidazolyl)pyridine derivatives induce cancer cell apoptosis by triggering DNA damage-mediated p53 phosphorylation.
    Dalton transactions (Cambridge, England : 2003), 2012, Nov-07, Volume: 41, Issue:41

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; DNA Damage; Histones; Humans; Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridines; Ruthenium; Tumor Suppressor Protein p53

2012
Arene-Ru(II) complexes of curcumin exert antitumor activity via proteasome inhibition and apoptosis induction.
    ChemMedChem, 2012, Volume: 7, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Curcumin; DNA; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Neoplasms; Oxidative Stress; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ruthenium

2012
Heterodinuclear ruthenium(II)-cobalt(III) complexes as models for a new approach to selective cancer treatment.
    Dalton transactions (Cambridge, England : 2003), 2012, Dec-21, Volume: 41, Issue:47

    Topics: Antineoplastic Agents; Cobalt; Coordination Complexes; Crystallography, X-Ray; Drug Delivery Systems; Electron Transport; Humans; Light; Models, Molecular; Neoplasms; Oxidation-Reduction; Phenanthrolines; Pyridines; Ruthenium

2012
INTRAGASTRIC BETA-IRRADIATION WITH RUTHENIUM- RHODIUM106 IN PATIENTS WITH PEPTIC ULCER AND GASTRIC NEOPLASM.
    Gastroenterology, 1963, Volume: 45

    Topics: Humans; Neoplasms; Peptic Ulcer; Rhodium; Ruthenium; Stomach Neoplasms; Stomach Ulcer

1963
CARCINOMA OF THE LUNG IN RATS EXPOSED TO THE BETA-RADIATION OF INTRABRONCHIAL RUTHENIUM PELLETS. I. DOSERESPONSE RELATIONSHIPS.
    Journal of the National Cancer Institute, 1963, Volume: 31

    Topics: Animals; Carcinoma; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Radiation-Induced; Research; Ruthenium

1963
TISSUE REACTIONS AND DOSE RELATIONSHIPS IN RATS FOLLOWING INTRAPULMONARY BETA RADIATION.
    Health physics, 1964, Volume: 10

    Topics: Beta Particles; Carcinoma, Squamous Cell; Lung Neoplasms; Neoplasms; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Pathology; Phosphorus Isotopes; Radiometry; Rats; Research; Ruthenium

1964
INHIBITION OF LANDSCHUETZ ASCITES TUMOUR GROWTH BY METAL CHELATES DERIVED FROM 3,4,7,8-TETRAMETHYL-1,10-PHENANTHROLINE.
    British journal of cancer, 1965, Volume: 19

    Topics: Animals; Antineoplastic Agents; Ascites; Copper; Metals; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Phenanthrolines; Research; Ruthenium

1965
Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.
    International journal of oncology, 2004, Volume: 24, Issue:2

    Topics: Animals; Cell Line, Tumor; Collagen; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Combinations; Inhibitory Concentration 50; Kidney; Laminin; Ligands; Liver; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred CBA; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Organometallic Compounds; Proteoglycans; Ruthenium; Ruthenium Compounds; Tissue Distribution

2004
Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:9

    Topics: Actin Cytoskeleton; Antibodies, Blocking; Antineoplastic Agents; Cell Adhesion; Cell Line; Dimethyl Sulfoxide; HeLa Cells; Humans; Integrins; Microscopy, Confocal; Microscopy, Electron, Scanning; Neoplasms; Neutrophils; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Trypsin

2004
Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins--significance for the patient.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:12

    Topics: Albumins; Antineoplastic Agents; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Indazoles; Neoplasms; Organometallic Compounds; Protein Binding; Ruthenium; Ruthenium Compounds; Spectrometry, Mass, Electrospray Ionization; Transferrin

2005
Radioactive ruthenium red accumulation by tumors: a potential scanning agent.
    Strahlentherapie, 1975, Volume: 149, Issue:2

    Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Coloring Agents; Glycosaminoglycans; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Radionuclide Imaging; Rats; Ruthenium

1975
[Tumor affinity of 103 Ru-ruthenocen-derivatives and 67gallium citrate].
    Strahlentherapie, 1978, Volume: 154, Issue:7

    Topics: Animals; Carcinoma, Ehrlich Tumor; Gallium Radioisotopes; Mice; Neoplasms; Radioisotopes; Radionuclide Imaging; Ruthenium

1978
[Electron microscopy demonstration of sulphurated acid mucopolysaccharides in canine mast cell tumors, using barium chloride and ruthenium red, together with comments on the classification and differentiation of tumor cells].
    Archiv fur experimentelle Veterinarmedizin, 1971, Volume: 25, Issue:6

    Topics: Animals; Barium; Chlorides; Dog Diseases; Dogs; Female; Glycosaminoglycans; Histocytochemistry; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Mast-Cell Sarcoma; Microscopy, Electron; Neoplasms; Ruthenium; Skin Neoplasms; Splenic Neoplasms; Staining and Labeling

1971