ruthenium has been researched along with Lung Neoplasms in 52 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (17.31) | 18.7374 |
1990's | 5 (9.62) | 18.2507 |
2000's | 10 (19.23) | 29.6817 |
2010's | 15 (28.85) | 24.3611 |
2020's | 13 (25.00) | 2.80 |
Authors | Studies |
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Azmanova, M; Cooper, PA; Pitto-Barry, A; Rafols, L; Seaton, CC; Shnyder, SD | 1 |
Barbosa, MIF; Candido, CC; Doriguetto, AC; Ionta, M; Silva, HVR; Zavan, B | 1 |
Ahmad, H; Chia, SL; Gill, MR; Saad, N; Yusoh, NA | 1 |
Chen, X; Liu, J; Liu, S; Yang, Y; Ye, G | 1 |
Du, J; Kang, Y; Luo, Q; Wang, F; Wang, Z; Wei, Y; Zhang, Y; Zhao, Y | 1 |
Fontrodona, X; Garcia, MH; Machuqueiro, M; Oliveira, NFB; Riganti, C; Romero, I; Salaroglio, IC; Sequeira, JGN; Teixeira, RG; Tomaz, AI; Valente, A | 1 |
Arsenijević, D; Arsenijević, M; Baošić, R; Lazić, D; Marković, Z; Međedović, M; Mijatović, A; Milanović, Ž; Milovanović, J; Milovanović, M; Petrović, B; Simović, AR; Stojanović, B | 1 |
Bhabak, KP; Bhattacherjee, D; Ganguly, R; Malviya, N; Mukhopadhyay, S; Sonkar, C | 1 |
Chen, Y; Li, Y; Ma, F; Qiao, X; Sun, L; Zhang, Y | 1 |
Brindell, M; Gros, PC; Gurgul, I; Mazuryk, O; Rutkowska-Zbik, D; Łomzik, M | 1 |
Chao, H; Gasser, G; Karges, J; Kuang, S; Ong, YC | 1 |
Batista, AA; Cominetti, MR; Correa, RS; Gonçalves, GR; Honorato, J; Oliveira, KM | 1 |
Gui, L; Li, Y; Liu, J; Lu, Y; Wang, W; Wang, Y; Zhu, D | 1 |
Li, Y; Shi, H; Sun, Q; Wang, Y; Zhang, J; Zhang, Q | 1 |
Comfort, K; Kilroy, MK; Morford, K; Swavey, S; Tsao, M | 1 |
Cierniak, A; Komarnicka, UK; Kołoczek, P; Kyzioł, A; Płotek, M; Sebastian, V; Skórska-Stania, A | 1 |
Batista, AA; Castellano, EE; Colina-Vegas, L; Cominetti, MR; Cunha, BN; Ferreira, AG; Honorato, J; Oliveira, KM; Plutín, AM; Silveira, RG | 1 |
Almeida, F; Barbosa, MIF; Colina-Vegas, L; Corrêa, CC; Dias, JSM; Doriguetto, AC; Ferreira-Silva, GÁ; Ionta, M; Silva, HVR | 1 |
Awasthi, S; Dayoub, AS; Hawkins, DL; Janaratne, T; Krishnan, A; MacDonnell, FM; Singhal, SS; Yadav, A; Yadav, S | 1 |
Chouai, A; Dorsey, C; Hennigar, R; Kohler, L; Lincoln, R; McFarland, SA; Monro, S; Stephenson, M; Thummel, RP; Yin, H; Zong, R | 1 |
Chen, Y; Hou, Y; Jiang, G; Lei, W; Li, C; Wang, X; Zhang, B; Zhou, Q | 1 |
Bergamo, A; Dyson, PJ; Riedel, T; Sava, G | 1 |
Alessio, E; Baas, P; Beijnen, JH; Burgers, SA; Leijen, S; Pluim, D; Sava, G; Schellens, JH; Tibben, M; van Werkhoven, E | 1 |
Batista, AA; Colina-Vegas, L; Cominetti, MR; de Oliveira, CR; Deflon, VM; Ferreira, AG; Graminha, AE; Maia, PIDS; Navarro, M; Villarreal, W | 1 |
Chao, H; Chen, Y; Huang, H; Ji, L; Wang, J; Zeng, L; Zhao, D | 1 |
Cai, K; Chen, J; Chen, L; Dongye, G; Feng, R; Jie, X; Li, B; Li, G; Lun, K; Peng, F; Xu, B; Zeng, Q | 1 |
Brabec, V; Bugarcic, T; Deeth, RJ; Habtemariam, A; Heringova, P; Johnstone, RD; Kasparkova, J; Parkin, A; Parsons, S; Prescimone, A; Sadler, PJ; Stepankova, J | 1 |
Chen, L; Chen, T; He, QY; Liu, J; Liu, Y; Yang, X; Yang, Y; Zheng, W | 1 |
Boscutti, G; Dalla Via, L; Fregona, D; Marchiò, L; Nagy, EM; Pettenuzzo, A | 1 |
Alessio, E; Bergamo, A; Cocchietto, M; Gava, B; Mestroni, G; Sava, G; Serli, B; Zorzet, S | 1 |
Bergamo, A; Cocchietto, M; DiGiovine, S; Garbisa, S; Pezzoni, G; Sartor, L; Sava, G; Soranzo, M; Turrin, C; Vita, F; Zabucchi, G; Zorzet, S | 1 |
Cocchietto, M; Sava, G; Sorc, A; Zorzet, S | 1 |
ALTSHULER, B; DANIELS, M; HARLEY, JH; KUSCHNER, M; LASKIN, S; NELSON, N | 1 |
ALTSHULER, B; KUSCHNER, M; LASKIN, S; NELSON, N | 1 |
Romanowska-Dixon, B | 1 |
Alessio, E; Bergamo, A; Casarsa, C; Cocchietto, M; Sava, G; Serli, B; Stocco, G; Zorzet, S | 1 |
Alessio, E; Bergamo, A; Casarsa, C; Cocchietto, M; Haasnoot, JG; Sava, G; Velders, AH; Zangrando, E; Zorzet, S | 1 |
Bacac, M; Castellarin, A; Cocchietto, M; Gava, B; Pacor, S; Sava, G; Turrin, C; Vadori, M; Zorzet, S | 1 |
Bergamo, A; Brescacin, L; Cocchietto, M; Delfino, R; Dyson, PJ; Geldbach, TJ; Laurenczy, G; Sava, G; Scolaro, C | 1 |
Divertie, MB; Shorter, RG; Titus, JL | 1 |
Iida, H; Sakurai, Y; Tsukagoshi, S; Tsuruo, T | 1 |
Giraldi, T; Mestroni, G; Sava, G; Zassinovich, G; Zorzet, S | 1 |
Giraldi, T; Mestroni, G; Sava, G; Zassinovich, G | 1 |
Alessio, E; Bergamo, A; Capozzi, I; Cocchietto, M; Mestroni, G; Sava, G | 1 |
Alessio, E; Capozzi, I; Clerici, K; Gagliardi, G; Mestroni, G; Sava, G | 1 |
Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G | 1 |
Alessio, E; Capozzi, I; Clerici, K; Cocchietto, M; Gagliardi, R; Mestroni, G; Perbellini, A; Sava, G | 1 |
Alessio, E; Bergamo, A; Boccarelli, A; Coluccia, M; Iengo, E; Sava, G; Zorzet, S | 1 |
Alessio, E; Bregant, F; Ceschia, V; Mestroni, G; Pacor, S; Sava, G | 1 |
Rudolph, R | 1 |
Balogh, I; Soós, J; Sótonyi, P; Szinay, G | 1 |
Kuschner, M | 1 |
1 review(s) available for ruthenium and Lung Neoplasms
Article | Year |
---|---|
Ruthenium Complexes as Promising Candidates against Lung Cancer.
Topics: Animals; Antineoplastic Agents; Coordination Complexes; Cytotoxins; Humans; Lung Neoplasms; Ruthenium | 2021 |
1 trial(s) available for ruthenium and Lung Neoplasms
Article | Year |
---|---|
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Dimethyl Sulfoxide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Treatment Outcome | 2015 |
50 other study(ies) available for ruthenium and Lung Neoplasms
Article | Year |
---|---|
Anticancer Water-Soluble Organoruthenium Complexes: Synthesis and Preclinical Evaluation.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Female; Humans; Ligands; Lung Neoplasms; Organophosphorus Compounds; Ovarian Neoplasms; Phosphines; Reactive Oxygen Species; Ruthenium; Water | 2022 |
Synthesis, characterization and in vitro cytotoxicity of ruthenium(II) metronidazole complexes: Cell cycle arrest at G1/S transition and apoptosis induction in MCF-7 cells.
Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Coordination Complexes; Humans; Ligands; Lung Neoplasms; MCF-7 Cells; Metronidazole; Ruthenium | 2022 |
Synergy of ruthenium metallo-intercalator, [Ru(dppz)
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA; Humans; Intercalating Agents; Lung Neoplasms; Phthalazines; Poly(ADP-ribose) Polymerase Inhibitors; Ruthenium; Zebrafish | 2023 |
Chiral Ruthenium Nanozymes with Self-Cascade Reaction Driven the NO Generation Induced Macrophage M1 Polarization Realizing the Lung Cancer "Cocktail Therapy".
Topics: Arginine; Humans; Lung Neoplasms; Macrophages; Nitric Oxide; Reactive Oxygen Species; Ruthenium | 2023 |
Ruthenium(II) polypyridyl complexes with visible light-enhanced anticancer activity and multimodal cell imaging.
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Ligands; Light; Lung Neoplasms; Ruthenium | 2023 |
Fighting Multidrug Resistance with Ruthenium-Cyclopentadienyl Compounds: Unveiling the Mechanism of P-gp Inhibition.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Molecular Docking Simulation; Ruthenium; Ruthenium Compounds | 2023 |
Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes.
Topics: Animals; Humans; Lung Neoplasms; Mice; Molecular Docking Simulation; Ruthenium; Schiff Bases | 2023 |
Novel Approach to Generate a Self-Deliverable Ru(II)-Based Anticancer Agent in the Self-Reacting Confined Gel Space.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Proliferation; Coordination Complexes; Dimethyl Sulfoxide; Gels; Humans; Lactic Acid; Lung Neoplasms; Molecular Docking Simulation; Pyrans; Ruthenium; Sulfhydryl Compounds | 2019 |
Signal-off/on electrogenerated chemiluminescence deoxyribosensors for assay of early lung cancer biomarker (NAP2) based on target-caused DNA charge transfer.
Topics: Aptamers, Nucleotide; Base Sequence; Biomarkers, Tumor; Biosensing Techniques; Coordination Complexes; DNA, Single-Stranded; Electrochemical Techniques; Electrodes; Humans; Immobilized Nucleic Acids; Limit of Detection; Luminescent Measurements; Lung Neoplasms; Nuclear Proteins; Nucleic Acid Conformation; Ruthenium | 2020 |
Unexplored features of Ru(ii) polypyridyl complexes - towards combined cytotoxic and antimetastatic activity.
Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Adhesion; Coordination Complexes; Humans; Lung Neoplasms; Pyridines; Ruthenium | 2020 |
One- and Two-Photon Phototherapeutic Effects of Ru
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; HeLa Cells; Humans; Lung Neoplasms; Mice; Neoplasms, Basal Cell; Organometallic Compounds; Photochemotherapy; Photons; Photosensitizing Agents; Pyridines; Ruthenium; Singlet Oxygen; Spheroids, Cellular; Tumor Hypoxia; Xenograft Model Antitumor Assays | 2021 |
Ru(II)/diclofenac-based complexes: DNA, BSA interaction and their anticancer evaluation against lung and breast tumor cells.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cattle; Cell Line, Tumor; Coordination Complexes; Diclofenac; DNA; Humans; Lung Neoplasms; Ruthenium; Serum Albumin, Bovine | 2020 |
A dual-targeting ruthenium nanodrug that inhibits primary tumor growth and lung metastasis via the PARP/ATM pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Lewis Lung; Cell Cycle; Cell Line, Tumor; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nanomedicine; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Transferrin; Ruthenium; Transferrin | 2021 |
Heteroleptic monometallic and trimetallic ruthenium(II) complexes incorporating a π-extended dipyrrin ligand: Light-activated reactions with the A549 lung cancer cell line.
Topics: A549 Cells; Coordination Complexes; DNA Damage; Humans; Light; Lung Neoplasms; Photochemotherapy; Ruthenium | 2017 |
Polymeric micelle-mediated delivery of half-sandwich ruthenium(II) complexes with phosphanes derived from fluoroloquinolones for lung adenocarcinoma treatment.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cisplatin; Coordination Complexes; DNA Fragmentation; Drug Carriers; Fluoroquinolones; Humans; Inhibitory Concentration 50; Lung Neoplasms; Micelles; Nanoparticles; Phosphines; Poloxalene; Ruthenium | 2018 |
Hydrolysis reaction promotes changes in coordination mode of Ru(II)/acylthiourea organometallic complexes with cytotoxicity against human lung tumor cell lines.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Humans; Hydrolysis; Lung Neoplasms; Organometallic Compounds; Ruthenium | 2018 |
Pro-apoptotic activity of ruthenium 1-methylimidazole complex on non-small cell lung cancer.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Coordination Complexes; Humans; Imidazoles; Lung Neoplasms; Ruthenium | 2018 |
Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; DNA Cleavage; Humans; Inhibitory Concentration 50; Lung Neoplasms; Male; Mice; Mice, Nude; Ruthenium; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Exploitation of long-lived 3IL excited states for metal-organic photodynamic therapy: verification in a metastatic melanoma model.
Topics: Adult; Cell Line, Tumor; Humans; Lung; Lung Neoplasms; Male; Melanoma; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Ruthenium | 2013 |
Fusion of photodynamic therapy and photoactivated chemotherapy: a novel Ru(II) arene complex with dual activities of photobinding and photocleavage toward DNA.
Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Cymenes; DNA; Humans; Lung Neoplasms; Models, Molecular; Monoterpenes; Photochemotherapy; Photosensitizing Agents; Pyridines; Quinoxalines; Ruthenium | 2014 |
Preclinical combination therapy of the investigational drug NAMI-A(+) with doxorubicin for mammary cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dimethyl Sulfoxide; Doxorubicin; Humans; Kidney; Liver; Lung; Lung Neoplasms; Mammary Neoplasms, Animal; MCF-7 Cells; Mice, Inbred CBA; Organometallic Compounds; Ruthenium; Ruthenium Compounds | 2015 |
Cytotoxicity of Ru(II) piano-stool complexes with chloroquine and chelating ligands against breast and lung tumor cells: Interactions with DNA and BSA.
Topics: Animals; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Cattle; Cell Line, Tumor; Chelating Agents; Chloroquine; Coordination Complexes; DNA; Electrochemical Techniques; Female; Humans; Intercalating Agents; Lung Neoplasms; Mice; Molecular Structure; Proton Magnetic Resonance Spectroscopy; Ruthenium; Serum Albumin, Bovine; Thermodynamics | 2015 |
Cyclometalated Ruthenium(II) Anthraquinone Complexes Exhibit Strong Anticancer Activity in Hypoxic Tumor Cells.
Topics: Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coordination Complexes; HeLa Cells; Hep G2 Cells; Humans; Hypoxia; Ligands; Lung Neoplasms; Ruthenium | 2015 |
The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Autophagosomes; Autophagy; Caspase 3; Cell Cycle Checkpoints; Cell Proliferation; Cytochromes c; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Mitochondria; Organometallic Compounds; Reactive Oxygen Species; Ruthenium; Signal Transduction; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
The contrasting chemistry and cancer cell cytotoxicity of bipyridine and bipyridinediol ruthenium(II) arene complexes.
Topics: 2,2'-Dipyridyl; Cations; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Female; Humans; Hydrogen Bonding; Hydrolysis; Lung Neoplasms; Magnetic Resonance Spectroscopy; Models, Molecular; Ovarian Neoplasms; Ruthenium; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured | 2008 |
Ruthenium methylimidazole complexes induced apoptosis in lung cancer A549 cells through intrinsic mitochondrial pathway.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Coordination Complexes; Gene Expression; Humans; Imidazoles; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Phenanthrolines; Proto-Oncogene Proteins c-bcl-2; Ruthenium; Signal Transduction | 2012 |
Ruthenium(II/III)-based compounds with encouraging antiproliferative activity against non-small-cell lung cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Humans; Lung Neoplasms; Molecular Conformation; Organometallic Compounds; Ruthenium | 2012 |
Ruthenium-based NAMI-A type complexes with in vivo selective metastasis reduction and in vitro invasion inhibition unrelated to cell cytotoxicity.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Dimethyl Sulfoxide; G2 Phase; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mitosis; Neoplasm Invasiveness; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Tumor Cells, Cultured | 2002 |
Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Adhesion; Cell Division; Collagen; Collagen Type IV; Dimethyl Sulfoxide; Drug Combinations; Female; Humans; Kidney; Laminin; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasm Invasiveness; Organometallic Compounds; Proteoglycans; Ruthenium; Ruthenium Compounds; Tumor Cells, Cultured | 2003 |
Primary tumor, lung and kidney retention and antimetastasis effect of NAMI-A following different routes of administration.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Dimethyl Sulfoxide; Disease Models, Animal; Female; Injections, Intraperitoneal; Kidney; Liver; Lung; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Species Specificity | 2003 |
CARCINOMA OF THE LUNG IN RATS EXPOSED TO THE BETA-RADIATION OF INTRABRONCHIAL RUTHENIUM PELLETS. I. DOSERESPONSE RELATIONSHIPS.
Topics: Animals; Carcinoma; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Radiation-Induced; Research; Ruthenium | 1963 |
TISSUE REACTIONS AND DOSE RELATIONSHIPS IN RATS FOLLOWING INTRAPULMONARY BETA RADIATION.
Topics: Beta Particles; Carcinoma, Squamous Cell; Lung Neoplasms; Neoplasms; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Pathology; Phosphorus Isotopes; Radiometry; Rats; Research; Ruthenium | 1964 |
[Treatment of intraocular metastatic tumors].
Topics: Adenocarcinoma; Adult; Aged; Brachytherapy; Carcinoid Tumor; Combined Modality Therapy; Eye Enucleation; Eye Neoplasms; Female; Fluorescein Angiography; Humans; Hyperthermia, Induced; Laser Coagulation; Laser Therapy; Lung Neoplasms; Male; Middle Aged; Ruthenium; Treatment Outcome | 2003 |
Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.
Topics: Animals; Cell Line, Tumor; Collagen; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Combinations; Inhibitory Concentration 50; Kidney; Laminin; Ligands; Liver; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred CBA; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Organometallic Compounds; Proteoglycans; Ruthenium; Ruthenium Compounds; Tissue Distribution | 2004 |
Synthesis and chemical-pharmacological characterization of the antimetastatic NAMI-A-type Ru(III) complexes (Hdmtp)[trans-RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7-dimethyl[1,2,4]triazolo[1,5-a]p
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Hydrolysis; Kidney; Liver; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Matrix Metalloproteinase 9; Mice; Molecular Structure; Neoplasm Invasiveness; Neoplasm Metastasis; Organometallic Compounds; Ruthenium; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tissue Distribution | 2004 |
Intratumoral NAMI-A treatment triggers metastasis reduction, which correlates to CD44 regulation and tumor infiltrating lymphocyte recruitment.
Topics: Animals; Dimethyl Sulfoxide; Female; Hyaluronan Receptors; Injections, Intralesional; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Organometallic Compounds; Ruthenium; Ruthenium Compounds | 2004 |
In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes.
Topics: Adamantane; Animals; Antineoplastic Agents; Benzene Derivatives; Buffers; Cell Line, Tumor; DNA; Female; Humans; Hydrolysis; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Organometallic Compounds; Organophosphorus Compounds; Ruthenium; Sodium Chloride; Solutions; Structure-Activity Relationship; Tissue Distribution; Xenograft Model Antitumor Assays | 2005 |
A simple method for the production of experimental squamous cell carcinoma of the lung in rats.
Topics: Animals; Carcinoma, Squamous Cell; Female; Lung Neoplasms; Male; Neoplasms, Experimental; Radioisotopes; Radiometry; Rats; Rhodium; Ruthenium | 1967 |
Growth inhibition of Lewis lung carcinoma by an inorganic dye, Ruthenium Red.
Topics: Animals; Antineoplastic Agents; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Rats; Ruthenium; Ruthenium Red | 1980 |
Antineoplastic activity and toxicity of an organometallic complex of ruthenium(II) in comparison with cis-PDD in mice bearing solid malignant neoplasms.
Topics: Animals; Antineoplastic Agents; Blood Cell Count; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Organometallic Compounds; Ruthenium | 1984 |
Antitumor effects of rhodium(I), iridium(I) and ruthenium(II) complexes in comparison with cis-dichlorodiammino platinum(II) in mice bearing Lewis lung carcinoma.
Topics: Animals; Antineoplastic Agents; Cisplatin; Iridium; Lethal Dose 50; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Organometallic Compounds; Rhodium; Ruthenium | 1983 |
Treatment of residual metastases with Na[trans-RuCl4 (DMSO)lm] and ruthenium uptake by tumor cells.
Topics: Animals; Antineoplastic Agents; Carcinoma; Dimethyl Sulfoxide; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm, Residual; Organometallic Compounds; Ruthenium; Survival Analysis | 1996 |
Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex.
Topics: Animals; Antineoplastic Agents; Carcinoma; Dimethyl Sulfoxide; Female; Flow Cytometry; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Organometallic Compounds; Ruthenium | 1998 |
Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cell Survival; Cisplatin; Dimethyl Sulfoxide; DNA, Neoplasm; Doxorubicin; Flow Cytometry; In Vitro Techniques; Lung Neoplasms; Lymphoma; Mice; Mice, Inbred CBA; Organometallic Compounds; Ruthenium; Tumor Cells, Cultured | 1998 |
Reduction of lung metastasis by ImH[trans-RuCl4(DMSO)Im]: mechanism of the selective action investigated on mouse tumors.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Lewis Lung; Cell Cycle; Dimethyl Sulfoxide; Female; Flow Cytometry; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred Strains; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Spectrophotometry, Atomic; Tissue Distribution | 1999 |
Antimetastatic properties and DNA interactions of the novel class of dimeric Ru(III) compounds Na2[[trans-RuCl4(Me2SO)]2(mu-L)] (L = ditopic, non-chelating aromatic N-ligand). A preliminary investigation.
Topics: Animals; Antineoplastic Agents; Dimerization; DNA; Female; Ligands; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Organometallic Compounds; Ruthenium | 2000 |
Antineoplastic effect of mer-trichlorobisdimethylsulphoxideaminorutheniumIII against murine tumors: comparison with cisplatin and with ImH[RuIm2Cl4].
Topics: Animals; Antineoplastic Agents; Carcinoma; Cisplatin; Imidazoles; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Organometallic Compounds; Ruthenium; Survival Analysis | 1991 |
[Electron microscopy demonstration of sulphurated acid mucopolysaccharides in canine mast cell tumors, using barium chloride and ruthenium red, together with comments on the classification and differentiation of tumor cells].
Topics: Animals; Barium; Chlorides; Dog Diseases; Dogs; Female; Glycosaminoglycans; Histocytochemistry; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Mast-Cell Sarcoma; Microscopy, Electron; Neoplasms; Ruthenium; Skin Neoplasms; Splenic Neoplasms; Staining and Labeling | 1971 |
[Ultrastructural studies of human lung biopsy material].
Topics: Biopsy; Cytoplasmic Granules; Extracellular Space; Humans; Inclusion Bodies; Lung; Lung Neoplasms; Pulmonary Alveoli; Ruthenium; Staining and Labeling | 1973 |
The causes of lung cancer.
Topics: Aerosols; Air Pollution; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; In Vitro Techniques; Lung; Lung Neoplasms; Methods; Methylcholanthrene; Mice; Models, Biological; Neoplasm Metastasis; Neoplasms, Experimental; Phosphorus Isotopes; Radioisotopes; Rats; Ruthenium; Smoking | 1968 |