Page last updated: 2024-08-22

ruthenium and Lung Neoplasms

ruthenium has been researched along with Lung Neoplasms in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19909 (17.31)18.7374
1990's5 (9.62)18.2507
2000's10 (19.23)29.6817
2010's15 (28.85)24.3611
2020's13 (25.00)2.80

Authors

AuthorsStudies
Azmanova, M; Cooper, PA; Pitto-Barry, A; Rafols, L; Seaton, CC; Shnyder, SD1
Barbosa, MIF; Candido, CC; Doriguetto, AC; Ionta, M; Silva, HVR; Zavan, B1
Ahmad, H; Chia, SL; Gill, MR; Saad, N; Yusoh, NA1
Chen, X; Liu, J; Liu, S; Yang, Y; Ye, G1
Du, J; Kang, Y; Luo, Q; Wang, F; Wang, Z; Wei, Y; Zhang, Y; Zhao, Y1
Fontrodona, X; Garcia, MH; Machuqueiro, M; Oliveira, NFB; Riganti, C; Romero, I; Salaroglio, IC; Sequeira, JGN; Teixeira, RG; Tomaz, AI; Valente, A1
Arsenijević, D; Arsenijević, M; Baošić, R; Lazić, D; Marković, Z; Međedović, M; Mijatović, A; Milanović, Ž; Milovanović, J; Milovanović, M; Petrović, B; Simović, AR; Stojanović, B1
Bhabak, KP; Bhattacherjee, D; Ganguly, R; Malviya, N; Mukhopadhyay, S; Sonkar, C1
Chen, Y; Li, Y; Ma, F; Qiao, X; Sun, L; Zhang, Y1
Brindell, M; Gros, PC; Gurgul, I; Mazuryk, O; Rutkowska-Zbik, D; Łomzik, M1
Chao, H; Gasser, G; Karges, J; Kuang, S; Ong, YC1
Batista, AA; Cominetti, MR; Correa, RS; Gonçalves, GR; Honorato, J; Oliveira, KM1
Gui, L; Li, Y; Liu, J; Lu, Y; Wang, W; Wang, Y; Zhu, D1
Li, Y; Shi, H; Sun, Q; Wang, Y; Zhang, J; Zhang, Q1
Comfort, K; Kilroy, MK; Morford, K; Swavey, S; Tsao, M1
Cierniak, A; Komarnicka, UK; Kołoczek, P; Kyzioł, A; Płotek, M; Sebastian, V; Skórska-Stania, A1
Batista, AA; Castellano, EE; Colina-Vegas, L; Cominetti, MR; Cunha, BN; Ferreira, AG; Honorato, J; Oliveira, KM; Plutín, AM; Silveira, RG1
Almeida, F; Barbosa, MIF; Colina-Vegas, L; Corrêa, CC; Dias, JSM; Doriguetto, AC; Ferreira-Silva, GÁ; Ionta, M; Silva, HVR1
Awasthi, S; Dayoub, AS; Hawkins, DL; Janaratne, T; Krishnan, A; MacDonnell, FM; Singhal, SS; Yadav, A; Yadav, S1
Chouai, A; Dorsey, C; Hennigar, R; Kohler, L; Lincoln, R; McFarland, SA; Monro, S; Stephenson, M; Thummel, RP; Yin, H; Zong, R1
Chen, Y; Hou, Y; Jiang, G; Lei, W; Li, C; Wang, X; Zhang, B; Zhou, Q1
Bergamo, A; Dyson, PJ; Riedel, T; Sava, G1
Alessio, E; Baas, P; Beijnen, JH; Burgers, SA; Leijen, S; Pluim, D; Sava, G; Schellens, JH; Tibben, M; van Werkhoven, E1
Batista, AA; Colina-Vegas, L; Cominetti, MR; de Oliveira, CR; Deflon, VM; Ferreira, AG; Graminha, AE; Maia, PIDS; Navarro, M; Villarreal, W1
Chao, H; Chen, Y; Huang, H; Ji, L; Wang, J; Zeng, L; Zhao, D1
Cai, K; Chen, J; Chen, L; Dongye, G; Feng, R; Jie, X; Li, B; Li, G; Lun, K; Peng, F; Xu, B; Zeng, Q1
Brabec, V; Bugarcic, T; Deeth, RJ; Habtemariam, A; Heringova, P; Johnstone, RD; Kasparkova, J; Parkin, A; Parsons, S; Prescimone, A; Sadler, PJ; Stepankova, J1
Chen, L; Chen, T; He, QY; Liu, J; Liu, Y; Yang, X; Yang, Y; Zheng, W1
Boscutti, G; Dalla Via, L; Fregona, D; Marchiò, L; Nagy, EM; Pettenuzzo, A1
Alessio, E; Bergamo, A; Cocchietto, M; Gava, B; Mestroni, G; Sava, G; Serli, B; Zorzet, S1
Bergamo, A; Cocchietto, M; DiGiovine, S; Garbisa, S; Pezzoni, G; Sartor, L; Sava, G; Soranzo, M; Turrin, C; Vita, F; Zabucchi, G; Zorzet, S1
Cocchietto, M; Sava, G; Sorc, A; Zorzet, S1
ALTSHULER, B; DANIELS, M; HARLEY, JH; KUSCHNER, M; LASKIN, S; NELSON, N1
ALTSHULER, B; KUSCHNER, M; LASKIN, S; NELSON, N1
Romanowska-Dixon, B1
Alessio, E; Bergamo, A; Casarsa, C; Cocchietto, M; Sava, G; Serli, B; Stocco, G; Zorzet, S1
Alessio, E; Bergamo, A; Casarsa, C; Cocchietto, M; Haasnoot, JG; Sava, G; Velders, AH; Zangrando, E; Zorzet, S1
Bacac, M; Castellarin, A; Cocchietto, M; Gava, B; Pacor, S; Sava, G; Turrin, C; Vadori, M; Zorzet, S1
Bergamo, A; Brescacin, L; Cocchietto, M; Delfino, R; Dyson, PJ; Geldbach, TJ; Laurenczy, G; Sava, G; Scolaro, C1
Divertie, MB; Shorter, RG; Titus, JL1
Iida, H; Sakurai, Y; Tsukagoshi, S; Tsuruo, T1
Giraldi, T; Mestroni, G; Sava, G; Zassinovich, G; Zorzet, S1
Giraldi, T; Mestroni, G; Sava, G; Zassinovich, G1
Alessio, E; Bergamo, A; Capozzi, I; Cocchietto, M; Mestroni, G; Sava, G1
Alessio, E; Capozzi, I; Clerici, K; Gagliardi, G; Mestroni, G; Sava, G1
Bergamo, A; Capozzi, I; Clerici, K; Cocchietto, M; Salerno, G; Sava, G1
Alessio, E; Capozzi, I; Clerici, K; Cocchietto, M; Gagliardi, R; Mestroni, G; Perbellini, A; Sava, G1
Alessio, E; Bergamo, A; Boccarelli, A; Coluccia, M; Iengo, E; Sava, G; Zorzet, S1
Alessio, E; Bregant, F; Ceschia, V; Mestroni, G; Pacor, S; Sava, G1
Rudolph, R1
Balogh, I; Soós, J; Sótonyi, P; Szinay, G1
Kuschner, M1

Reviews

1 review(s) available for ruthenium and Lung Neoplasms

ArticleYear
Ruthenium Complexes as Promising Candidates against Lung Cancer.
    Molecules (Basel, Switzerland), 2021, Jul-21, Volume: 26, Issue:15

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Cytotoxins; Humans; Lung Neoplasms; Ruthenium

2021

Trials

1 trial(s) available for ruthenium and Lung Neoplasms

ArticleYear
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.
    Investigational new drugs, 2015, Volume: 33, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Dimethyl Sulfoxide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Treatment Outcome

2015

Other Studies

50 other study(ies) available for ruthenium and Lung Neoplasms

ArticleYear
Anticancer Water-Soluble Organoruthenium Complexes: Synthesis and Preclinical Evaluation.
    Chembiochem : a European journal of chemical biology, 2022, 09-16, Volume: 23, Issue:18

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Female; Humans; Ligands; Lung Neoplasms; Organophosphorus Compounds; Ovarian Neoplasms; Phosphines; Reactive Oxygen Species; Ruthenium; Water

2022
Synthesis, characterization and in vitro cytotoxicity of ruthenium(II) metronidazole complexes: Cell cycle arrest at G1/S transition and apoptosis induction in MCF-7 cells.
    Journal of inorganic biochemistry, 2022, Volume: 237

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Coordination Complexes; Humans; Ligands; Lung Neoplasms; MCF-7 Cells; Metronidazole; Ruthenium

2022
Synergy of ruthenium metallo-intercalator, [Ru(dppz)
    Scientific reports, 2023, 01-26, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA; Humans; Intercalating Agents; Lung Neoplasms; Phthalazines; Poly(ADP-ribose) Polymerase Inhibitors; Ruthenium; Zebrafish

2023
Chiral Ruthenium Nanozymes with Self-Cascade Reaction Driven the NO Generation Induced Macrophage M1 Polarization Realizing the Lung Cancer "Cocktail Therapy".
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:28

    Topics: Arginine; Humans; Lung Neoplasms; Macrophages; Nitric Oxide; Reactive Oxygen Species; Ruthenium

2023
Ruthenium(II) polypyridyl complexes with visible light-enhanced anticancer activity and multimodal cell imaging.
    Dalton transactions (Cambridge, England : 2003), 2023, Sep-13, Volume: 52, Issue:35

    Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Ligands; Light; Lung Neoplasms; Ruthenium

2023
Fighting Multidrug Resistance with Ruthenium-Cyclopentadienyl Compounds: Unveiling the Mechanism of P-gp Inhibition.
    Journal of medicinal chemistry, 2023, 10-26, Volume: 66, Issue:20

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Molecular Docking Simulation; Ruthenium; Ruthenium Compounds

2023
Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes.
    Journal of inorganic biochemistry, 2023, Volume: 248

    Topics: Animals; Humans; Lung Neoplasms; Mice; Molecular Docking Simulation; Ruthenium; Schiff Bases

2023
Novel Approach to Generate a Self-Deliverable Ru(II)-Based Anticancer Agent in the Self-Reacting Confined Gel Space.
    ACS applied materials & interfaces, 2019, Dec-18, Volume: 11, Issue:50

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Proliferation; Coordination Complexes; Dimethyl Sulfoxide; Gels; Humans; Lactic Acid; Lung Neoplasms; Molecular Docking Simulation; Pyrans; Ruthenium; Sulfhydryl Compounds

2019
Signal-off/on electrogenerated chemiluminescence deoxyribosensors for assay of early lung cancer biomarker (NAP2) based on target-caused DNA charge transfer.
    Analytica chimica acta, 2020, Mar-22, Volume: 1103

    Topics: Aptamers, Nucleotide; Base Sequence; Biomarkers, Tumor; Biosensing Techniques; Coordination Complexes; DNA, Single-Stranded; Electrochemical Techniques; Electrodes; Humans; Immobilized Nucleic Acids; Limit of Detection; Luminescent Measurements; Lung Neoplasms; Nuclear Proteins; Nucleic Acid Conformation; Ruthenium

2020
Unexplored features of Ru(ii) polypyridyl complexes - towards combined cytotoxic and antimetastatic activity.
    Metallomics : integrated biometal science, 2020, 05-27, Volume: 12, Issue:5

    Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Adhesion; Coordination Complexes; Humans; Lung Neoplasms; Pyridines; Ruthenium

2020
One- and Two-Photon Phototherapeutic Effects of Ru
    Chemistry (Weinheim an der Bergstrasse, Germany), 2021, Jan-04, Volume: 27, Issue:1

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; HeLa Cells; Humans; Lung Neoplasms; Mice; Neoplasms, Basal Cell; Organometallic Compounds; Photochemotherapy; Photons; Photosensitizing Agents; Pyridines; Ruthenium; Singlet Oxygen; Spheroids, Cellular; Tumor Hypoxia; Xenograft Model Antitumor Assays

2021
Ru(II)/diclofenac-based complexes: DNA, BSA interaction and their anticancer evaluation against lung and breast tumor cells.
    Dalton transactions (Cambridge, England : 2003), 2020, Sep-22, Volume: 49, Issue:36

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cattle; Cell Line, Tumor; Coordination Complexes; Diclofenac; DNA; Humans; Lung Neoplasms; Ruthenium; Serum Albumin, Bovine

2020
A dual-targeting ruthenium nanodrug that inhibits primary tumor growth and lung metastasis via the PARP/ATM pathway.
    Journal of nanobiotechnology, 2021, Apr-23, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Lewis Lung; Cell Cycle; Cell Line, Tumor; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nanomedicine; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Transferrin; Ruthenium; Transferrin

2021
Heteroleptic monometallic and trimetallic ruthenium(II) complexes incorporating a π-extended dipyrrin ligand: Light-activated reactions with the A549 lung cancer cell line.
    Journal of inorganic biochemistry, 2017, Volume: 175

    Topics: A549 Cells; Coordination Complexes; DNA Damage; Humans; Light; Lung Neoplasms; Photochemotherapy; Ruthenium

2017
Polymeric micelle-mediated delivery of half-sandwich ruthenium(II) complexes with phosphanes derived from fluoroloquinolones for lung adenocarcinoma treatment.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 128

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cisplatin; Coordination Complexes; DNA Fragmentation; Drug Carriers; Fluoroquinolones; Humans; Inhibitory Concentration 50; Lung Neoplasms; Micelles; Nanoparticles; Phosphines; Poloxalene; Ruthenium

2018
Hydrolysis reaction promotes changes in coordination mode of Ru(II)/acylthiourea organometallic complexes with cytotoxicity against human lung tumor cell lines.
    Journal of inorganic biochemistry, 2018, Volume: 186

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Humans; Hydrolysis; Lung Neoplasms; Organometallic Compounds; Ruthenium

2018
Pro-apoptotic activity of ruthenium 1-methylimidazole complex on non-small cell lung cancer.
    Journal of inorganic biochemistry, 2018, Volume: 187

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Coordination Complexes; Humans; Imidazoles; Lung Neoplasms; Ruthenium

2018
Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; DNA Cleavage; Humans; Inhibitory Concentration 50; Lung Neoplasms; Male; Mice; Mice, Nude; Ruthenium; Tumor Burden; Xenograft Model Antitumor Assays

2013
Exploitation of long-lived 3IL excited states for metal-organic photodynamic therapy: verification in a metastatic melanoma model.
    Journal of the American Chemical Society, 2013, Nov-13, Volume: 135, Issue:45

    Topics: Adult; Cell Line, Tumor; Humans; Lung; Lung Neoplasms; Male; Melanoma; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Ruthenium

2013
Fusion of photodynamic therapy and photoactivated chemotherapy: a novel Ru(II) arene complex with dual activities of photobinding and photocleavage toward DNA.
    Dalton transactions (Cambridge, England : 2003), 2014, Nov-07, Volume: 43, Issue:41

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Cymenes; DNA; Humans; Lung Neoplasms; Models, Molecular; Monoterpenes; Photochemotherapy; Photosensitizing Agents; Pyridines; Quinoxalines; Ruthenium

2014
Preclinical combination therapy of the investigational drug NAMI-A(+) with doxorubicin for mammary cancer.
    Investigational new drugs, 2015, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dimethyl Sulfoxide; Doxorubicin; Humans; Kidney; Liver; Lung; Lung Neoplasms; Mammary Neoplasms, Animal; MCF-7 Cells; Mice, Inbred CBA; Organometallic Compounds; Ruthenium; Ruthenium Compounds

2015
Cytotoxicity of Ru(II) piano-stool complexes with chloroquine and chelating ligands against breast and lung tumor cells: Interactions with DNA and BSA.
    Journal of inorganic biochemistry, 2015, Volume: 153

    Topics: Animals; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Cattle; Cell Line, Tumor; Chelating Agents; Chloroquine; Coordination Complexes; DNA; Electrochemical Techniques; Female; Humans; Intercalating Agents; Lung Neoplasms; Mice; Molecular Structure; Proton Magnetic Resonance Spectroscopy; Ruthenium; Serum Albumin, Bovine; Thermodynamics

2015
Cyclometalated Ruthenium(II) Anthraquinone Complexes Exhibit Strong Anticancer Activity in Hypoxic Tumor Cells.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Oct-19, Volume: 21, Issue:43

    Topics: Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coordination Complexes; HeLa Cells; Hep G2 Cells; Humans; Hypoxia; Ligands; Lung Neoplasms; Ruthenium

2015
The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Autophagosomes; Autophagy; Caspase 3; Cell Cycle Checkpoints; Cell Proliferation; Cytochromes c; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Mitochondria; Organometallic Compounds; Reactive Oxygen Species; Ruthenium; Signal Transduction; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2016
The contrasting chemistry and cancer cell cytotoxicity of bipyridine and bipyridinediol ruthenium(II) arene complexes.
    Inorganic chemistry, 2008, Dec-15, Volume: 47, Issue:24

    Topics: 2,2'-Dipyridyl; Cations; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Female; Humans; Hydrogen Bonding; Hydrolysis; Lung Neoplasms; Magnetic Resonance Spectroscopy; Models, Molecular; Ovarian Neoplasms; Ruthenium; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured

2008
Ruthenium methylimidazole complexes induced apoptosis in lung cancer A549 cells through intrinsic mitochondrial pathway.
    Biochimie, 2012, Volume: 94, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Coordination Complexes; Gene Expression; Humans; Imidazoles; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Phenanthrolines; Proto-Oncogene Proteins c-bcl-2; Ruthenium; Signal Transduction

2012
Ruthenium(II/III)-based compounds with encouraging antiproliferative activity against non-small-cell lung cancer.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Nov-05, Volume: 18, Issue:45

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Humans; Lung Neoplasms; Molecular Conformation; Organometallic Compounds; Ruthenium

2012
Ruthenium-based NAMI-A type complexes with in vivo selective metastasis reduction and in vitro invasion inhibition unrelated to cell cytotoxicity.
    International journal of oncology, 2002, Volume: 21, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Dimethyl Sulfoxide; G2 Phase; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mitosis; Neoplasm Invasiveness; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Tumor Cells, Cultured

2002
Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Adhesion; Cell Division; Collagen; Collagen Type IV; Dimethyl Sulfoxide; Drug Combinations; Female; Humans; Kidney; Laminin; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasm Invasiveness; Organometallic Compounds; Proteoglycans; Ruthenium; Ruthenium Compounds; Tumor Cells, Cultured

2003
Primary tumor, lung and kidney retention and antimetastasis effect of NAMI-A following different routes of administration.
    Investigational new drugs, 2003, Volume: 21, Issue:1

    Topics: Administration, Inhalation; Administration, Oral; Aerosols; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Dimethyl Sulfoxide; Disease Models, Animal; Female; Injections, Intraperitoneal; Kidney; Liver; Lung; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Species Specificity

2003
CARCINOMA OF THE LUNG IN RATS EXPOSED TO THE BETA-RADIATION OF INTRABRONCHIAL RUTHENIUM PELLETS. I. DOSERESPONSE RELATIONSHIPS.
    Journal of the National Cancer Institute, 1963, Volume: 31

    Topics: Animals; Carcinoma; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Radiation-Induced; Research; Ruthenium

1963
TISSUE REACTIONS AND DOSE RELATIONSHIPS IN RATS FOLLOWING INTRAPULMONARY BETA RADIATION.
    Health physics, 1964, Volume: 10

    Topics: Beta Particles; Carcinoma, Squamous Cell; Lung Neoplasms; Neoplasms; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Pathology; Phosphorus Isotopes; Radiometry; Rats; Research; Ruthenium

1964
[Treatment of intraocular metastatic tumors].
    Klinika oczna, 2003, Volume: 105, Issue:3-4

    Topics: Adenocarcinoma; Adult; Aged; Brachytherapy; Carcinoid Tumor; Combined Modality Therapy; Eye Enucleation; Eye Neoplasms; Female; Fluorescein Angiography; Humans; Hyperthermia, Induced; Laser Coagulation; Laser Therapy; Lung Neoplasms; Male; Middle Aged; Ruthenium; Treatment Outcome

2003
Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.
    International journal of oncology, 2004, Volume: 24, Issue:2

    Topics: Animals; Cell Line, Tumor; Collagen; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Combinations; Inhibitory Concentration 50; Kidney; Laminin; Ligands; Liver; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred CBA; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Organometallic Compounds; Proteoglycans; Ruthenium; Ruthenium Compounds; Tissue Distribution

2004
Synthesis and chemical-pharmacological characterization of the antimetastatic NAMI-A-type Ru(III) complexes (Hdmtp)[trans-RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7-dimethyl[1,2,4]triazolo[1,5-a]p
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Hydrolysis; Kidney; Liver; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Matrix Metalloproteinase 9; Mice; Molecular Structure; Neoplasm Invasiveness; Neoplasm Metastasis; Organometallic Compounds; Ruthenium; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tissue Distribution

2004
Intratumoral NAMI-A treatment triggers metastasis reduction, which correlates to CD44 regulation and tumor infiltrating lymphocyte recruitment.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Female; Hyaluronan Receptors; Injections, Intralesional; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Organometallic Compounds; Ruthenium; Ruthenium Compounds

2004
In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes.
    Journal of medicinal chemistry, 2005, Jun-16, Volume: 48, Issue:12

    Topics: Adamantane; Animals; Antineoplastic Agents; Benzene Derivatives; Buffers; Cell Line, Tumor; DNA; Female; Humans; Hydrolysis; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Organometallic Compounds; Organophosphorus Compounds; Ruthenium; Sodium Chloride; Solutions; Structure-Activity Relationship; Tissue Distribution; Xenograft Model Antitumor Assays

2005
A simple method for the production of experimental squamous cell carcinoma of the lung in rats.
    The American review of respiratory disease, 1967, Volume: 96, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Female; Lung Neoplasms; Male; Neoplasms, Experimental; Radioisotopes; Radiometry; Rats; Rhodium; Ruthenium

1967
Growth inhibition of Lewis lung carcinoma by an inorganic dye, Ruthenium Red.
    Gan, 1980, Volume: 71, Issue:1

    Topics: Animals; Antineoplastic Agents; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Rats; Ruthenium; Ruthenium Red

1980
Antineoplastic activity and toxicity of an organometallic complex of ruthenium(II) in comparison with cis-PDD in mice bearing solid malignant neoplasms.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Agents; Blood Cell Count; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Organometallic Compounds; Ruthenium

1984
Antitumor effects of rhodium(I), iridium(I) and ruthenium(II) complexes in comparison with cis-dichlorodiammino platinum(II) in mice bearing Lewis lung carcinoma.
    Chemico-biological interactions, 1983, Jul-01, Volume: 45, Issue:1

    Topics: Animals; Antineoplastic Agents; Cisplatin; Iridium; Lethal Dose 50; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Organometallic Compounds; Rhodium; Ruthenium

1983
Treatment of residual metastases with Na[trans-RuCl4 (DMSO)lm] and ruthenium uptake by tumor cells.
    Anti-cancer drugs, 1996, Volume: 7, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma; Dimethyl Sulfoxide; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm, Residual; Organometallic Compounds; Ruthenium; Survival Analysis

1996
Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinoma; Dimethyl Sulfoxide; Female; Flow Cytometry; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Organometallic Compounds; Ruthenium

1998
Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry.
    Chemico-biological interactions, 1998, May-01, Volume: 113, Issue:1

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cell Survival; Cisplatin; Dimethyl Sulfoxide; DNA, Neoplasm; Doxorubicin; Flow Cytometry; In Vitro Techniques; Lung Neoplasms; Lymphoma; Mice; Mice, Inbred CBA; Organometallic Compounds; Ruthenium; Tumor Cells, Cultured

1998
Reduction of lung metastasis by ImH[trans-RuCl4(DMSO)Im]: mechanism of the selective action investigated on mouse tumors.
    Anti-cancer drugs, 1999, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Lewis Lung; Cell Cycle; Dimethyl Sulfoxide; Female; Flow Cytometry; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred Strains; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Spectrophotometry, Atomic; Tissue Distribution

1999
Antimetastatic properties and DNA interactions of the novel class of dimeric Ru(III) compounds Na2[[trans-RuCl4(Me2SO)]2(mu-L)] (L = ditopic, non-chelating aromatic N-ligand). A preliminary investigation.
    Journal of inorganic biochemistry, 2000, Volume: 79, Issue:1-4

    Topics: Animals; Antineoplastic Agents; Dimerization; DNA; Female; Ligands; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Organometallic Compounds; Ruthenium

2000
Antineoplastic effect of mer-trichlorobisdimethylsulphoxideaminorutheniumIII against murine tumors: comparison with cisplatin and with ImH[RuIm2Cl4].
    Chemico-biological interactions, 1991, Volume: 78, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cisplatin; Imidazoles; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Organometallic Compounds; Ruthenium; Survival Analysis

1991
[Electron microscopy demonstration of sulphurated acid mucopolysaccharides in canine mast cell tumors, using barium chloride and ruthenium red, together with comments on the classification and differentiation of tumor cells].
    Archiv fur experimentelle Veterinarmedizin, 1971, Volume: 25, Issue:6

    Topics: Animals; Barium; Chlorides; Dog Diseases; Dogs; Female; Glycosaminoglycans; Histocytochemistry; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Mast-Cell Sarcoma; Microscopy, Electron; Neoplasms; Ruthenium; Skin Neoplasms; Splenic Neoplasms; Staining and Labeling

1971
[Ultrastructural studies of human lung biopsy material].
    Morphologiai es igazsagugyi orvosi szemle, 1973, Volume: 13, Issue:3

    Topics: Biopsy; Cytoplasmic Granules; Extracellular Space; Humans; Inclusion Bodies; Lung; Lung Neoplasms; Pulmonary Alveoli; Ruthenium; Staining and Labeling

1973
The causes of lung cancer.
    The American review of respiratory disease, 1968, Volume: 98, Issue:4

    Topics: Aerosols; Air Pollution; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; In Vitro Techniques; Lung; Lung Neoplasms; Methods; Methylcholanthrene; Mice; Models, Biological; Neoplasm Metastasis; Neoplasms, Experimental; Phosphorus Isotopes; Radioisotopes; Rats; Ruthenium; Smoking

1968