rutecarpine has been researched along with Disease Models, Animal in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 7 (38.89) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Bhavan, PS; Chung, CL; Hou, SM; Hsia, CH; Hsia, CW; Huang, WC; Jayakumar, T; Sheu, JR; Wu, MP | 1 |
| Gong, M; Jia, J | 1 |
| Gao, R; He, B; Lei, J; Lei, X; Pan, Y; Wang, Z; Yan, M; Yang, N; Zhang, Z | 1 |
| Chen, Y; Han, M; Hu, L | 1 |
| Devi, RV; Singh, CB; Singh, OJ; Surbala, L | 1 |
| Cai, YT; Dong, YH; Jiang, L; Jin, J; Li, J; Li, Z; Liu, MM; Liu, XQ; Ma, TT; Meng, XM; Wang, JN; Wen, JG; Wu, MF; Wu, YG | 1 |
| Chu, Y; Gu, P; Hui, X; Lin, S; Liu, X; Loomes, K; Mao, L; Nie, T; Tang, S; Wu, D; Xu, Y; Zhang, Y; Zhao, S; Zhao, X | 1 |
| Hao, Z; Liang, C; Sun, Y; Wang, C; Zhang, L; Zhou, J | 1 |
| Chen, XP; Hou, HH; Lin, SX; Sun, AS; Xu, Y; Zhang, F; Zhang, JY | 1 |
| Chen, M; Li, Y; Tang, F; Tong, M; Wen, H; Xiao, R; Zhang, G; Zhao, M | 1 |
| Du, J; Li, D; Li, WQ; Li, XH; Li, YJ; Xiong, XM; Zhang, W | 1 |
| Chen, SY; Deng, SX; Li, D; Li, YJ; Liao, DF; Qin, XP; Ren, JF; Tian, HH; Zeng, SY; Zheng, YB | 1 |
| Chen, F; Ding, JS; Li, D; Li, S | 1 |
| Deng, PY; Ding, JS; Hu, CP; Li, YJ; Shen, SS; Tan, GS; Wang, L; Zhu, HQ | 1 |
| Bae, EA; Cai, XF; Kim, DH; Lee, JJ; Shin, YW | 1 |
| Chen, QQ; Deng, HW; Hu, GY; Li, D; Li, YJ; Luo, D; Qin, XP; Zeng, SY; Zhang, Z | 1 |
18 other study(ies) available for rutecarpine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB.
Topics: Animals; Disease Models, Animal; Fibrinolytic Agents; Free Radical Scavengers; Free Radicals; Humans; I-kappa B Kinase; Imidazoles; Indole Alkaloids; Male; Mice, Inbred ICR; NF-kappa B; Nitriles; P-Selectin; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Protein Kinase Inhibitors; Pulmonary Embolism; Pyridines; Quinazolines; Sulfones; Thrombosis; Transcription Factor RelA | 2022 |
Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Cognitive Dysfunction; Disease Models, Animal; Mice; Mitochondria; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | 2023 |
Rutaecarpine induces the differentiation of triple-negative breast cancer cells through inhibiting fumarate hydratase.
Topics: Animals; Cell Differentiation; Chromatography, Liquid; Disease Models, Animal; Fumarate Hydratase; Humans; Mice; Reactive Oxygen Species; Tandem Mass Spectrometry; Triple Negative Breast Neoplasms | 2023 |
Rutaecarpine may improve neuronal injury, inhibits apoptosis, inflammation and oxidative stress by regulating the expression of ERK1/2 and Nrf2/HO-1 pathway in rats with cerebral ischemia-reperfusion injury.
Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Heme Oxygenase-1; Indole Alkaloids; Inflammation; Male; MAP Kinase Signaling System; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Quinazolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2019 |
Rutaecarpine exhibits anti-diabetic potential in high fat diet-multiple low dose streptozotocin induced type 2 diabetic mice and in vitro by modulating hepatic glucose homeostasis.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucose; Homeostasis; Hypoglycemic Agents; Indole Alkaloids; Liver; Male; Mice, Inbred C57BL; Quinazolines | 2020 |
Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cisplatin; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Epithelial Cells; Humans; Indole Alkaloids; Kidney Tubules; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Oxidative Stress; Protein Binding; Quinazolines | 2020 |
The natural compound rutaecarpine promotes white adipocyte browning through activation of the AMPK-PRDM16 axis.
Topics: Adipocytes, Beige; Adipocytes, White; AMP-Activated Protein Kinases; Animals; Biological Products; Disease Models, Animal; DNA-Binding Proteins; Drug Evaluation, Preclinical; In Vitro Techniques; Indole Alkaloids; Male; Mice; Mice, Transgenic; Models, Biological; Obesity; Oxygen Consumption; Quinazolines; Signal Transduction; Thermogenesis; Transcription Factors | 2021 |
Rutaecarpine alleviates renal ischemia reperfusion injury in rats by suppressing the JNK/p38 MAPK signaling pathway and interfering with the oxidative stress response.
Topics: Animals; Biomarkers; Biopsy; Blood Urea Nitrogen; Cytokines; Disease Models, Animal; Indole Alkaloids; Inflammation Mediators; Kidney Diseases; Kidney Function Tests; Male; MAP Kinase Signaling System; Oxidative Stress; Phosphorylation; Protective Agents; Quinazolines; Rats; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2017 |
Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model.
Topics: Actins; Animals; Carotid Arteries; Carotid Artery Injuries; Cyclic GMP; Disease Models, Animal; Gene Expression Regulation; Hyperplasia; Indole Alkaloids; Male; Nitric Oxide; Phosphorylation; Proliferating Cell Nuclear Antigen; Quinazolines; Rats, Sprague-Dawley; RNA, Messenger; Tunica Intima | 2018 |
Rutaecarpine inhibited imiquimod-induced psoriasis-like dermatitis via inhibiting the NF-κB and TLR7 pathways in mice.
Topics: Animals; Dermatitis; Disease Models, Animal; Imiquimod; Indole Alkaloids; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; Quinazolines; Signal Transduction; Skin; Skin Diseases; Th17 Cells; Toll-Like Receptor 7 | 2019 |
Rutaecarpine attenuates hypoxia-induced right ventricular remodeling in rats.
Topics: Animals; Apoptosis; Calcitonin Gene-Related Peptide; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-3; Fibroblasts; Fibrosis; Hypertrophy, Right Ventricular; Hypoxia; Indole Alkaloids; Myocardium; Quinazolines; Signal Transduction; Transforming Growth Factor beta1; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling | 2016 |
Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Carboxypeptidases; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renovascular; Hypertrophy; Indole Alkaloids; Kallikreins; Losartan; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2009 |
Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo.
Topics: Administration, Cutaneous; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Evodia; Female; Indole Alkaloids; Male; Mice; Oleic Acid; Pain; Plant Extracts; Quinazolines; Sesquiterpenes; Skin; Swine | 2012 |
The protective effects of rutaecarpine on gastric mucosa injury in rats.
Topics: Alkaloids; Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Evodia; Female; Gastric Mucosa; Indole Alkaloids; Male; Phytotherapy; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2005 |
In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents.
Topics: Alkaloids; Animals; Anti-Allergic Agents; Behavior, Animal; Cell Degranulation; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Evodia; Fruit; Indole Alkaloids; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Plant Extracts; Pruritus; Quinazolines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2007 |
Calcitonin gene-related Peptide-mediated depressor effect and inhibiting vascular hypertrophy of rutaecarpine in renovascular hypertensive rats.
Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Vessels; Calcitonin Gene-Related Peptide; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renovascular; Hypertrophy; Hypotension; Indole Alkaloids; Losartan; Male; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Quinazolines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Vasodilator Agents | 2007 |