Page last updated: 2024-08-24

rutecarpine and Alzheimer Disease

rutecarpine has been researched along with Alzheimer Disease in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Han, J; Ji, L; Li, Z; Ma, J; Wang, M; Wu, M1
Dong, YH; Huang, XF; Ke, HM; Song, GQ; Wang, JH; Xu, DF1
An, XW; Chen, C; Chen, F; Hu, N; Jia, XL; Li, XH; Liu, R; Sun, HT; Wang, JJ; Wang, Y; Zhao, B; Zheng, CG1
Chen, JG; Li, X; Wu, YG1
Chen, SB; Gu, LQ; He, Y; Huang, SL; Huang, ZH; Huang, ZS; Li, D; Tan, JH; Yao, PF1

Other Studies

5 other study(ies) available for rutecarpine and Alzheimer Disease

ArticleYear
Design, synthesis, and biological evaluation of rutacecarpine derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Sep-01, Volume: 177

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line, Tumor; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protective Agents; Protein Multimerization; Rats; Structure-Activity Relationship; Sulfonamides

2019
Novel PDE5 inhibitors derived from rutaecarpine for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2020, 05-01, Volume: 30, Issue:9

    Topics: Alzheimer Disease; Animals; Cholinergic Antagonists; Cognitive Dysfunction; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Indole Alkaloids; Mice; Models, Molecular; Molecular Structure; Morris Water Maze Test; Phosphodiesterase 5 Inhibitors; Protein Conformation; Quinazolines; Scopolamine

2020
Rutaecarpine Ameliorated High Sucrose-Induced Alzheimer's Disease Like Pathological and Cognitive Impairments in Mice.
    Rejuvenation research, 2021, Volume: 24, Issue:3

    Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Glycogen Synthase Kinase 3 beta; Indole Alkaloids; Mice; Phosphorylation; Quinazolines; Sucrose

2021
[Effect of rutaecarpine on Alzheimer's disease-like cognitive impairments induced by high glucose in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2019, Volume: 35, Issue:2

    Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Glucose; Glycogen Synthase Kinase 3 beta; Indole Alkaloids; Male; Maze Learning; Phosphorylation; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; tau Proteins

2019
Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Biocatalysis; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Indole Alkaloids; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Molecular Structure; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Quinazolines

2013