rufinamide has been researched along with Aura in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.08) | 18.2507 |
| 2000's | 15 (30.61) | 29.6817 |
| 2010's | 27 (55.10) | 24.3611 |
| 2020's | 5 (10.20) | 2.80 |
| Authors | Studies |
|---|---|
| Imai, K; Inoue, Y; Kagawa, Y; Takahashi, Y; Usui, N; Yamamoto, Y | 1 |
| Bozarth, XL; Oesch, G | 1 |
| Caraballo, RH; Espeche, A; Fasulo, L; Galichio, S; Pociecha, J; Reyes, G; Semprino, M | 1 |
| Beccaria, F; Capovilla, G; De Giorgis, V; Fattore, C; Franco, V; Galimberti, CA; Gatti, G; Johannessen Landmark, C; Marchiselli, R; Mazzucchelli, I; Perucca, E; Rota, P | 1 |
| Loddenkemper, T; Tanritanir, A; Wang, X | 1 |
| Bebin, EM; Cutter, GR; Gaston, TE; Liu, Y; Szaflarski, JP | 1 |
| Battaglia, D; Coppola, G; Curatolo, P; Cusmai, R; D'Aniello, A; Di Gennaro, G; Matricardi, S; Moavero, R; Parisi, P; Pruna, D; Spalice, A; Verrotti, A; Vigevano, F | 1 |
| Bosmans, F; Diaz-Bustamante, M; Dutton, S; Escayg, A; Gilchrist, J; Kalia, J; McPherson, A; Olivares, N | 1 |
| Ito, S; Oguni, H | 1 |
| Ohtsuka, Y | 1 |
| Accorsi, P; Balestri, P; Coppola, G; Dontin, SD; Gobbi, G; Grosso, S; Parisi, P; Pruna, D; Verrotti, A | 1 |
| Besag, F; Coppola, G; Curatolo, P; Cusmai, R; Dulac, O; Kluger, G; Moavero, R; Nabbout, R; Nikanorova, M; Pisani, F; Verrotti, A; von Stülpnagel, C | 1 |
| Bergin, AM; Bolton, J; Bourgeois, BF; Harini, C; Kadish, NE; Kapur, K; Kothare, SV; Libenson, M; Loddenkemper, T; Olson, H; Peters, J; Poduri, A; Ramgopal, S; Rotenberg, A; Sánchez Fernández, I; Takeoka, M; Thome-Souza, S | 1 |
| Alsaad, AM; Koren, G | 1 |
| Awaya, T; Heike, T; Ide, M; Kato, T; Nakata, M; Saito, K; Yoshida, T | 1 |
| Cnaan, A; Dlugos, DJ; Kessler, SK; McCarthy, A | 1 |
| Bast, T; Boor, R; Ernst, JP; Haberlandt, E; Kluger, G; Kurlemann, G; Makowski, C; Runge, U; Schneider, F | 2 |
| Stafstrom, CE | 1 |
| Verdian, L; Yi, Y | 1 |
| Conry, J; Krauss, G; LoPresti, A; Mann, A; Narurkar, M; Wheless, JW | 1 |
| Albani, F; Baruzzi, A; Candela, C; Contin, M; Mohamed, S; Riva, R | 1 |
| Best, R; Hutchinson, DJ; Liou, Y; Zhao, F | 1 |
| Arroyo, S; Glauser, T; Kluger, G; Krauss, G; Perdomo, C; Seeruthun, R | 1 |
| Wisniewski, CS | 1 |
| Balestri, A; Coppola, G; Curatolo, P; D'Aniello, A; Fels, A; Franzoni, E; Grosso, S; Habetswallner, F; Mangano, S; Parisi, P; Pascotto, A; Spalice, A; Veggiotti, P; Verrotti, A; Zamponi, N | 1 |
| Bergin, AM; Bourgeois, BF; Duffy, FH; Eksioglu, YZ; Gooty, VD; Kothare, SV; Libenson, M; Loddenkemper, T; Poduri, A; Rotenberg, A; Takeoka, M; Vendrame, M | 1 |
| Falchi, M; Filippi, L; Guerrini, R; Innocenti, M; la Marca, G; Malvagia, S; Moneti, G; Pellacani, S; Rosati, A | 1 |
| Joseph, JR; Schultz, RJ; Wilfong, AA | 1 |
| Bergin, AM; Bourgeois, BF; Coulter, D; Duffy, FH; Kothare, SV; Libenson, MH; Loddenkemper, T; Olson, HE; Poduri, A; Rotenberg, A; Takeoka, M; Vendrame, M | 1 |
| Perucca, E; Prunetti, P | 1 |
| Ballone, E; Chiarelli, F; Curatolo, P; Loiacono, G; Mattei, PA; Verrotti, A | 1 |
| Antzelevitch, C; Borggrefe, M; Brandt, C; Ebner, A; Göksu, T; Kuschyk, J; Papavassiliu, T; Rudic, B; Schimpf, R; Veltmann, C; Wolpert, C | 1 |
| Crespel, A; Gelisse, P; Mourand, I | 1 |
| Dahlin, MG; Ohman, I | 1 |
| Anderson, GD; Cheng-Hakimian, A; Miller, JW | 1 |
| Arroyo, S | 1 |
| Anderson, GD; Cheng-Hakimian, A; Hakimian, S; Miller, JW | 1 |
| Heaney, D; Walker, MC | 1 |
| Kreutzkamp, B | 1 |
| Arroyo, S; Glauser, T; Kluger, G; Krauss, G; Perdomo, C; Sachdeo, R | 1 |
| Cloyd, J; Critchley, D; Fuseau, E; Perucca, E | 1 |
| Alif, L; Godbillon, J; Lecaillon, JB; Moes, D; Rouan, MC; Souppart, C | 1 |
| Bialer, M; Johannessen, SI; Kupferberg, HJ; Levy, RH; Loiseau, P; Perucca, E | 1 |
| Jain, KK | 1 |
| Canger, R; Henriksen, O; Karolchyk, MA; Pålhagen, S; Rivière, ME; van Parys, JA | 1 |
| Aldenkamp, AP | 1 |
16 review(s) available for rufinamide and Aura
| Article | Year |
|---|---|
[Treatment of pediatric epilepsy].
Topics: Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Substitution; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Patient Education as Topic; Piracetam; Practice Guidelines as Topic; Topiramate; Triazines; Triazoles; Valproic Acid | 2014 |
[New antiepileptic drugs: characteristics and clinical applications].
Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Lamotrigine; Levetiracetam; Piracetam; Safety; Topiramate; Triazines; Triazoles | 2014 |
Current role of rufinamide in the treatment of childhood epilepsy: literature review and treatment guidelines.
Topics: Anticonvulsants; Epilepsy; Female; Guidelines as Topic; Humans; Male; Triazoles | 2014 |
Exposure to rufinamide and risks of CNS adverse events in drug-resistant epilepsy: a meta-analysis of randomized, placebo-controlled trials.
Topics: Anticonvulsants; Central Nervous System Diseases; Disorders of Excessive Somnolence; Dizziness; Drug Resistance; Epilepsy; Fatigue; Headache; Humans; Randomized Controlled Trials as Topic; Risk; Triazoles | 2014 |
Safety and tolerability of rufinamide in children with epilepsy: a pooled analysis of 7 clinical studies.
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Disorders of Excessive Somnolence; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Female; Headache; Humans; Male; Treatment Outcome; Triazoles; Vomiting | 2009 |
Rufinamide: a new antiepileptic medication for the treatment of seizures associated with lennox-gastaut syndrome.
Topics: Aged; Anticonvulsants; Chemistry, Pharmaceutical; Child; Clinical Trials, Phase III as Topic; Counseling; Drug Resistance; Epilepsies, Partial; Epilepsy; Humans; Off-Label Use; Randomized Controlled Trials as Topic; Seizures; Syndrome; Triazoles | 2010 |
Rufinamide for refractory epilepsy in a pediatric and young adult population.
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Longitudinal Studies; Male; Treatment Outcome; Triazoles; Young Adult | 2011 |
New and forthcoming anti-epileptic drugs.
Topics: Acetamides; Anticonvulsants; Clinical Trials as Topic; Dioxolanes; Drug Approval; Drug Discovery; Epilepsy; Humans; Lacosamide; Remission Induction; Triazoles | 2011 |
Efficacy of rufinamide in drug-resistant epilepsy: a meta-analysis.
Topics: Anticonvulsants; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Humans; Odds Ratio; Triazoles | 2011 |
Rufinamide: CGP 33101, E 2080, RUF 331, Xilep.
Topics: Anticonvulsants; Clinical Trials as Topic; Drug Interactions; Drugs, Investigational; Epilepsy; Humans; Triazoles | 2005 |
Rufinamide: Pharmacology, clinical trials, and role in clinical practice.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Humans; Triazoles | 2006 |
Rufinamide.
Topics: Animals; Anticonvulsants; Brain; Clinical Trials as Topic; Epilepsy; Humans; Triazoles | 2007 |
Rufinamide: a new anti-epileptic medication.
Topics: Adult; Animals; Anticonvulsants; Child; Drug Interactions; Epilepsy; Humans; Randomized Controlled Trials as Topic; Syndrome; Triazoles | 2007 |
Rufinamide.
Topics: Animals; Anticonvulsants; Drug Interactions; Epilepsy; Humans; Triazoles | 2007 |
[Rufinamide. An orphan drug for treatment of Lennox-Gastaut syndrome].
Topics: Anticonvulsants; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Male; Syndrome; Triazoles | 2007 |
An assessment of rufinamide as an anti-epileptic in comparison with other drugs in clinical development.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Humans; Triazoles | 2000 |
5 trial(s) available for rufinamide and Aura
| Article | Year |
|---|---|
Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Female; Humans; Longitudinal Studies; Male; Treatment Outcome; Triazoles; Young Adult | 2010 |
Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Brain Diseases; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Triazoles; Young Adult | 2011 |
Efficacy of rufinamide in drug-resistant epilepsy: a meta-analysis.
Topics: Anticonvulsants; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Humans; Odds Ratio; Triazoles | 2011 |
Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Male; Syndrome; Treatment Outcome; Triazoles | 2008 |
Rufinamide: a double-blind, placebo-controlled proof of principle trial in patients with epilepsy.
Topics: Adult; Anticonvulsants; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Incidence; Male; Middle Aged; Nervous System Diseases; Seizures; Triazoles | 2001 |
29 other study(ies) available for rufinamide and Aura
| Article | Year |
|---|---|
Therapeutic Drug Monitoring for Rufinamide in Japanese Patients With Epilepsy: Focus on Drug Interactions, Tolerability, and Clinical Effectiveness.
Topics: Anticonvulsants; Drug Interactions; Drug Monitoring; Epilepsy; Humans; Japan; Retrospective Studies; Seizures; Treatment Outcome; Triazoles | 2022 |
Rufinamide efficacy and association with phenotype and genotype in children with intractable epilepsy: A retrospective single center study.
Topics: Anticonvulsants; Child; Child, Preschool; Drug Resistant Epilepsy; Epilepsy; Female; Genotype; Humans; Infant; Lennox Gastaut Syndrome; Male; Phenotype; Retrospective Studies; Seizures; Triazoles | 2020 |
Rufinamide as add-on therapy in children with epileptic encephalopathies other than Lennox-Gastaut syndrome: A study of 34 patients.
Topics: Adolescent; Anticonvulsants; Argentina; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Lennox Gastaut Syndrome; Male; Retrospective Studies; Seizures; Triazoles; Valproic Acid | 2020 |
Relationship between saliva and plasma rufinamide concentrations in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Drug Monitoring; Epilepsy; Female; Humans; Male; Saliva; Triazoles; Young Adult | 2020 |
Efficacy and Tolerability of Rufinamide in Epileptic Children Younger Than 4 Years.
Topics: Age Factors; Anticonvulsants; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Retrospective Studies; Treatment Outcome; Triazoles | 2021 |
Interactions between cannabidiol and commonly used antiepileptic drugs.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Benzodiazepines; Cannabidiol; Child; Child, Preschool; Clobazam; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Topiramate; Triazoles; Young Adult | 2017 |
Rufinamide for the treatment of refractory epilepsy secondary to neuronal migration disorders.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Germany; Humans; Italy; Male; Malformations of Cortical Development, Group II; Prospective Studies; Treatment Outcome; Triazoles; Young Adult | 2014 |
Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents.
Topics: Action Potentials; Animals; Anticonvulsants; Cells, Cultured; Drug Discovery; Epilepsy; Hippocampus; Humans; Male; Mice; NAV1.1 Voltage-Gated Sodium Channel; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles; Xenopus | 2014 |
Efficacy and safety of rufinamide in children under four years of age with drug-resistant epilepsies.
Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Male; Retrospective Studies; Treatment Outcome; Triazoles | 2014 |
Safety and retention rate of rufinamide in 300 patients: a single pediatric epilepsy center experience.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Male; Patient Compliance; Prospective Studies; Retrospective Studies; Sleep Wake Disorders; Treatment Outcome; Triazoles; Vomiting; Young Adult | 2014 |
A granulocytosis associated with rufinamide: A case report.
Topics: Agranulocytosis; Anticonvulsants; Child; Clonazepam; Epilepsy; Humans; Male; Triazoles; Valproic Acid | 2015 |
Retention rates of rufinamide in pediatric epilepsy patients with and without Lennox-Gastaut Syndrome.
Topics: Adolescent; Anticonvulsants; Child; Cohort Studies; Epilepsy; Female; Humans; Kaplan-Meier Estimate; Lennox Gastaut Syndrome; Male; Treatment Outcome; Triazoles | 2015 |
Effectiveness and tolerability of rufinamide in children and adults with refractory epilepsy: first European experience.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Resistance; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Europe; Female; Humans; Infant; Male; Middle Aged; Orphan Drug Production; Retrospective Studies; Seizures; Treatment Outcome; Triazoles; Young Adult | 2009 |
American Epilepsy Society--62nd Annual Meeting. 5-9 December 2008, Seattle, USA.
Topics: Animals; Anticonvulsants; Biomarkers; Clinical Trials as Topic; Epilepsy; Humans; Infant; Ketones; Societies, Scientific; Spasms, Infantile; Triazoles; United States | 2009 |
Rufinamide (Banzel) for epilepsy.
Topics: Anticonvulsants; Clinical Trials as Topic; Drug Interactions; Epilepsy; Humans; Treatment Outcome; Triazoles | 2009 |
Cost-utility analysis of rufinamide versus topiramate and lamotrigine for the treatment of children with Lennox-Gastaut Syndrome in the United Kingdom.
Topics: Anticonvulsants; Child; Confidence Intervals; Cost-Benefit Analysis; Drug Utilization; Epilepsy; Follow-Up Studies; Fructose; Health Status; Humans; Lamotrigine; Markov Chains; Quality of Life; Sensitivity and Specificity; Topiramate; Triazines; Triazoles; United Kingdom | 2010 |
Simultaneous HPLC-UV analysis of rufinamide, zonisamide, lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in deproteinized plasma of patients with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Felbamate; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Triazoles; Ultraviolet Rays; Zonisamide | 2010 |
Stability of extemporaneously prepared rufinamide oral suspensions.
Topics: Adult; Anticonvulsants; Child; Chromatography, High Pressure Liquid; Drug Compounding; Drug Packaging; Drug Stability; Drug Storage; Epilepsy; Humans; Pharmaceutical Vehicles; Polypropylenes; Suspensions; Time Factors; Triazoles | 2010 |
First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Epilepsy; Europe; Female; Humans; Infant; Longitudinal Studies; Male; Middle Aged; Orphan Drug Production; Product Surveillance, Postmarketing; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Triazoles; Young Adult | 2010 |
Experience with rufinamide in a pediatric population: a single center's experience.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Pediatrics; Retrospective Studies; Seizures; Treatment Outcome; Triazoles; Young Adult | 2010 |
Rapid assay of rufinamide in dried blood spots by a new liquid chromatography-tandem mass spectrometric method.
Topics: Anticonvulsants; Blood Specimen Collection; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Child, Preschool; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Male; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry; Triazoles | 2011 |
Rufinamide for the treatment of epileptic spasms.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Male; Retrospective Studies; Spasms, Infantile; Treatment Outcome; Triazoles; Young Adult | 2011 |
Drug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide.
Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Electrocardiography; Epilepsy; Female; Follow-Up Studies; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Male; Middle Aged; Spasms, Infantile; Triazoles; Young Adult | 2012 |
Dramatic weight loss with rufinamide.
Topics: Adolescent; Adult; Anticonvulsants; Body Mass Index; Epilepsy; Female; Humans; Male; Triazoles; Weight Loss; Young Adult | 2013 |
Rufinamide in children with refractory epilepsy: pharmacokinetics, efficacy, and safety.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Male; Retrospective Studies; Triazoles; Valproic Acid | 2012 |
Rufinamide: clinical pharmacokinetics and concentration-response relationships in patients with epilepsy.
Topics: Administration, Oral; Adolescent; Age Factors; Anticonvulsants; Body Mass Index; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Food; Half-Life; Humans; Intrinsic Factor; Kidney Diseases; Liver Diseases; Male; Metabolic Clearance Rate; Renal Dialysis; Sex Factors; Syndrome; Triazoles | 2008 |
Automated analysis of a novel anti-epileptic compound, CGP 33,101, and its metabolite, CGP 47,292, in body fluids by high-performance liquid chromatography and liquid-solid extraction.
Topics: Anticonvulsants; Autoanalysis; Chromatography, High Pressure Liquid; Epilepsy; Humans; Hydrogen-Ion Concentration; Microchemistry; Quality Control; Sensitivity and Specificity; Solubility; Triazoles | 1995 |
Progress report on new antiepileptic drugs: a summary of the Third Eilat Conference.
Topics: Acetamides; Animals; Anticonvulsants; Azetidines; Carbamates; Drug Evaluation, Preclinical; Drugs, Investigational; Epilepsy; Humans; Israel; Levetiracetam; Nipecotic Acids; Phenylenediamines; Piracetam; Product Surveillance, Postmarketing; Randomized Controlled Trials as Topic; Thiazoles; Tiagabine; Triazoles | 1996 |
Effects of antiepileptic drugs on cognition.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin | 2001 |