Compounds > ruboxistaurin
Page last updated: 2024-09-04

ruboxistaurin and Myocardial Infarction

ruboxistaurin has been researched along with Myocardial Infarction in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ge, ZD; Irwin, MG; Jin, J; Lei, S; Li, H; Liao, S; Liu, Y; Qiao, S; Wong, GT; Xia, Z1
Chen, X; Houser, SR; Kranias, EG; Leitges, M; Liu, Q; Lorenz, JN; Macdonnell, SM; Molkentin, JD1
Correll, RN; Hajjar, RJ; Houser, SR; Ishikawa, K; Kawase, Y; Ladage, D; Molkentin, JD; Tilemann, L1
Belmonte, SL; Blaxall, BC1
Boyle, AJ; Cox, AJ; Gilbert, RE; Gow, RM; Itescu, S; Kelly, DJ; Krum, H; Way, K; Zhang, Y1

Other Studies

5 other study(ies) available for ruboxistaurin and Myocardial Infarction

ArticleYear
Inhibition of PKCβ2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:4

    Topics: Animals; Apoptosis; Caveolin 3; Cell Line; Diabetes Mellitus, Experimental; Dinoprost; Enzyme Activation; Indoles; Isoprostanes; Male; Maleimides; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphorylation; Phthalimides; Protein Kinase C beta; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Time Factors; Transfection; Ventricular Function, Left

2015
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach.
    Circulation research, 2009, Jul-17, Volume: 105, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Calcium Signaling; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Failure; Indoles; Maleimides; Metoprolol; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Infarction; Myocardium; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase Inhibitors; Pulmonary Edema; Time Factors

2009
Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.
    Circulation research, 2011, Dec-09, Volume: 109, Issue:12

    Topics: Animals; Cardiac Output; Coronary Occlusion; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heart; Heart Failure; Indoles; Maleimides; Myocardial Contraction; Myocardial Infarction; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Stroke Volume; Swine

2011
PKC-ing is believing: targeting protein kinase C in heart failure.
    Circulation research, 2011, Dec-09, Volume: 109, Issue:12

    Topics: Animals; Enzyme Inhibitors; Female; Heart Failure; Indoles; Maleimides; Myocardial Infarction; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha

2011
Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction.
    Journal of molecular and cellular cardiology, 2005, Volume: 39, Issue:2

    Topics: Animals; Collagen; Echocardiography; Extracellular Matrix; Fibrosis; Gene Expression Regulation; Heart Ventricles; In Situ Hybridization; Indoles; Male; Maleimides; Myocardial Infarction; Protein Kinase C; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Ventricular Dysfunction, Left

2005