ruboxistaurin has been researched along with Macular Edema in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (78.57) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aiello, LP; Bek, T; Berg, PH; Cunha-Vaz, J; Danis, R; Davis, MD; Shahri, N; Sheetz, MJ | 1 |
| Aiello, LP; Danis, RP; Davis, MD; Girach, A; Jimenez, MC; Milton, RC; Sheetz, MJ; Vignati, L; Zhi, X | 1 |
| Gálvez, MI | 1 |
| Gardner, TW; Girach, A; Larsen, M; Zhi, X | 1 |
| Majji, AB; Sahu, AK | 1 |
| Aiello, LP; Davis, MD; Girach, A; Milton, RC; Shahri, N; Sheetz, MJ; Vignati, L; Wolka, AM; Zhi, X | 1 |
| Aiello, LP | 1 |
| Kitano, S | 1 |
| Aiello, LP; Klemp, K; Larsen, M; Lund-Andersen, H; Sander, B; Strøm, C | 1 |
| Angioi-Duprez, K | 1 |
| Aiello, LP; Davis, MD; Girach, A; Kles, KA; Milton, RC; Sheetz, MJ; Vignati, L; Zhi, XE | 1 |
| Emerson, MV; Lauer, AK | 1 |
| Fraser-Bell, S; Hykin, PG; Kaines, A | 1 |
6 review(s) available for ruboxistaurin and Macular Edema
| Article | Year |
|---|---|
Rubosixtaurin and other PKC inhibitors in diabetic retinopathy and macular edema. Review.
Topics: Diabetic Retinopathy; Enzyme Inhibitors; Humans; Hyperglycemia; Indoles; Macular Edema; Maleimides; Neovascularization, Pathologic; Protein Kinase C | 2009 |
The potential role of PKC beta in diabetic retinopathy and macular edema.
Topics: Animals; Diabetic Retinopathy; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Macular Edema; Maleimides; Protein Kinase C; Protein Kinase C beta | 2002 |
[Medications for diabetic macular edema].
Topics: Acetazolamide; Diabetic Retinopathy; Diagnostic Techniques, Ophthalmological; Humans; Indoles; Injections, Intralesional; Macular Edema; Maleimides; Prognosis; Protein Kinase C; Protein Kinase C beta; Pyrroles; Triamcinolone Acetonide; Vascular Endothelial Growth Factor A | 2005 |
[Retinopathy, a major cause of blindness in the adult diabetic].
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blindness; Causality; Diabetic Retinopathy; Disease Progression; Fluorescein Angiography; Humans; Indoles; Laser Therapy; Light Coagulation; Macular Edema; Maleimides; Octreotide; Ophthalmology; Protein Kinase C; Retinal Detachment; Severity of Illness Index; Tetrazoles; Tomography, Optical Coherence; Vision Screening; Visual Acuity; Vitrectomy | 2006 |
Emerging therapies for the treatment of neovascular age-related macular degeneration and diabetic macular edema.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Cholestanols; Choroidal Neovascularization; Diabetic Retinopathy; Drug Therapy, Combination; Humans; Indoles; Lactates; Laser Coagulation; Macular Degeneration; Macular Edema; Maleimides; Octreotide; Photochemotherapy; Photosensitizing Agents; Porphyrins; Pregnadienediols; Protein-Tyrosine Kinases; Vascular Endothelial Growth Factors; Verteporfin; Vitrectomy | 2007 |
Update on treatments for diabetic macular edema.
Topics: Diabetes Complications; Enzyme Inhibitors; Fluocinolone Acetonide; Glucocorticoids; Humans; Indoles; Injections; Laser Coagulation; Macular Edema; Maleimides; Protein Kinase C; Treatment Outcome; Triamcinolone Acetonide; Vitrectomy; Vitreous Body | 2008 |
7 trial(s) available for ruboxistaurin and Macular Edema
| Article | Year |
|---|---|
The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies.
Topics: Administration, Oral; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Prospective Studies; Protein Kinase C; Protein Kinase C beta; Sickness Impact Profile; Surveys and Questionnaires; Tomography, Optical Coherence; Vision Disorders; Visual Acuity | 2013 |
Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Severity of Illness Index; Time Factors; Vision Disorders; Vision Tests; Visual Acuity | 2009 |
Diabetic macular oedema and visual loss: relationship to location, severity and duration.
Topics: Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Indoles; Macula Lutea; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Severity of Illness Index; Time Factors; Vision Disorders; Visual Acuity | 2009 |
Oral protein kinase c β inhibition using ruboxistaurin: efficacy, safety, and causes of vision loss among 813 patients (1,392 eyes) with diabetic retinopathy in the Protein Kinase C β Inhibitor-Diabetic Retinopathy Study and the Protein Kinase C β Inhibit
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Protein Kinase C beta; Treatment Outcome; Vision Disorders; Visual Acuity; Young Adult | 2011 |
Effect of ruboxistaurin on blood-retinal barrier permeability in relation to severity of leakage in diabetic macular edema.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Blood-Retinal Barrier; Capillary Permeability; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Glycated Hemoglobin; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Retina; Retinal Vessels | 2005 |
Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Diabetic Retinopathy; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Protein Kinase C beta; Vision Disorders; Visual Acuity | 2006 |
Effect of ruboxistaurin in patients with diabetic macular edema: thirty-month results of the randomized PKC-DMES clinical trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Laser Coagulation; Macular Edema; Male; Maleimides; Middle Aged; Prospective Studies; Protein Kinase C; Protein Kinase C beta; Treatment Outcome; Visual Acuity | 2007 |
1 other study(ies) available for ruboxistaurin and Macular Edema
| Article | Year |
|---|---|
Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema.
Topics: Administration, Oral; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Enzyme Inhibitors; Humans; Indoles; Macular Edema; Maleimides; Protein Kinase C; Severity of Illness Index; Vision Disorders; Vision Tests; Visual Acuity | 2010 |