ruboxistaurin has been researched along with Hyperglycemia, Postprandial in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gálvez, MI | 1 |
| Haller, H; Meier, M; Menne, J | 1 |
| Bradley, TJ; Cherney, DZ; Lai, V; Reich, HN; Scholey, JW; Slorach, C; Zinman, B | 1 |
| Gupta, A; Kamble, B; Kuppusamy, G; Pathak, D; Suresh, B | 1 |
| Bohlen, HG | 1 |
| Donnelly, R; Idris, I | 1 |
| Dutour, A | 1 |
| Ishii, H; Jirousek, MR; King, GL; Koya, D; Kuboki, K; Lin, YW | 1 |
| Bursell, SE; Clermont, AC; Ishii, H; King, GL; Mori, F; Takagi, C; Takagi, H | 1 |
| Bohlen, HG; Nase, GP | 1 |
| Gutterman, DD | 1 |
| Beckman, JA; Creager, MA; Garrett, LA; Goldfine, AB; Gordon, MB | 1 |
4 review(s) available for ruboxistaurin and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
Rubosixtaurin and other PKC inhibitors in diabetic retinopathy and macular edema. Review.
Topics: Diabetic Retinopathy; Enzyme Inhibitors; Humans; Hyperglycemia; Indoles; Macular Edema; Maleimides; Neovascularization, Pathologic; Protein Kinase C | 2009 |
Targeting the protein kinase C family in the diabetic kidney: lessons from analysis of mutant mice.
Topics: Animals; Diabetic Nephropathies; Diabetic Neuropathies; Enzyme Activation; Enzyme Inhibitors; Humans; Hyperglycemia; Indoles; Isoenzymes; Kidney; Maleimides; Mice; Mice, Knockout; Mice, Mutant Strains; Mice, Transgenic; Models, Animal; Protein Kinase C; Protein Kinase C beta; Risk Factors | 2009 |
Oral targeting of protein kinase C receptor: promising route for diabetic retinopathy?
Topics: Administration, Oral; Animals; Clinical Trials, Phase III as Topic; Diabetic Retinopathy; Enzyme Inhibitors; Humans; Hyperglycemia; Indoles; Maleimides; Molecular Targeted Therapy; Protein Kinase C; Vascular Endothelial Growth Factor A | 2012 |
Protein kinase C beta inhibition: A novel therapeutic strategy for diabetic microangiopathy.
Topics: Animals; Diabetic Angiopathies; Endothelium, Vascular; Humans; Hyperglycemia; Hypoglycemic Agents; Indoles; Maleimides; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Randomized Controlled Trials as Topic; Treatment Outcome; Vascular Endothelial Growth Factor A | 2006 |
2 trial(s) available for ruboxistaurin and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
Systemic hemodynamic function in humans with type 1 diabetes treated with protein kinase Cβ inhibition and renin-angiotensin system blockade: a pilot study.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Type 1; Enzyme Inhibitors; Female; Glucose Clamp Technique; Hemodynamics; Humans; Hyperglycemia; Indoles; Infusions, Intravenous; Male; Maleimides; Pilot Projects; Protein Kinase C; Protein Kinase C beta; Renin-Angiotensin System | 2012 |
Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans.
Topics: Adult; Blood Flow Velocity; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Hyperglycemia; Indoles; Isoenzymes; Male; Maleimides; Methacholine Chloride; Protein Kinase C; Protein Kinase C beta; Vasodilation | 2002 |
6 other study(ies) available for ruboxistaurin and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
Protein kinase betaII in Zucker obese rats compromises oxygen and flow-mediated regulation of nitric oxide formation.
Topics: Animals; Arterioles; Blood Flow Velocity; Body Weight; Enzyme Inhibitors; Hyperglycemia; Indoles; Maleimides; Nitric Oxide; Obesity; Oxygen Consumption; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Stress, Mechanical; Thinness | 2004 |
Mechanisms of glucose toxicity. New hope for prevention of diabetic complications?
Topics: Animals; Diabetes Mellitus; Diabetic Angiopathies; Enzyme Inhibitors; Glucose; Hyperglycemia; Indoles; Maleimides; Rats | 1997 |
Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats.
Topics: Administration, Oral; Animals; Arachidonic Acid; Cells, Cultured; Collagen; Diabetes Mellitus, Experimental; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibronectins; Glomerular Mesangium; Glucose; Hyperglycemia; Indoles; Kidney Glomerulus; Male; Maleimides; Prostaglandins; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Transcription, Genetic; Transforming Growth Factor beta | 1997 |
Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats.
Topics: Animals; Blood Flow Velocity; Diabetes Mellitus, Experimental; Diacylglycerol Kinase; Diglycerides; Enzyme Inhibitors; Fluorescein Angiography; Hyperglycemia; Indoles; Isoenzymes; Male; Maleimides; Piperidines; Protein Kinase C; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels | 1997 |
Arteriolar nitric oxide concentration is decreased during hyperglycemia-induced betaII PKC activation.
Topics: Acetylcholine; Animals; Arterioles; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Hyperglycemia; Hypertonic Solutions; Indoles; Isoenzymes; Jejunum; Male; Maleimides; Nitric Oxide; Nitroprusside; Osmotic Pressure; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley; Sodium Chloride; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Vascular dysfunction in hyperglycemia: is protein kinase C the culprit?
Topics: Blood Flow Velocity; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Humans; Hyperglycemia; Indoles; Maleimides; Protein Kinase C; Vasodilation | 2002 |