Page last updated: 2024-09-04

ruboxistaurin and Day Blindness

ruboxistaurin has been researched along with Day Blindness in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (55.56)	29.6817
2010's	4 (44.44)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aiello, LP; Bek, T; Berg, PH; Cunha-Vaz, J; Danis, R; Davis, MD; Shahri, N; Sheetz, MJ	1
Aiello, LP; Danis, RP; Davis, MD; Girach, A; Jimenez, MC; Milton, RC; Sheetz, MJ; Vignati, L; Zhi, X	1
Aiello, LP; Danis, RP; Davis, MD; Girach, A; Milton, RC; Sheetz, MJ; Vignati, L; Zhi, X	1
Gardner, TW; Girach, A; Larsen, M; Zhi, X	1
Majji, AB; Sahu, AK	1
Aiello, LP; Danis, RP; Davis, MD; Kles, KA; Shahri, N; Sheetz, MJ	1
Aiello, LP; Davis, MD; Girach, A; Milton, RC; Shahri, N; Sheetz, MJ; Vignati, L; Wolka, AM; Zhi, X	1
Aiello, LP; Davis, MD; Girach, A; Kles, KA; Milton, RC; Sheetz, MJ; Vignati, L; Zhi, XE	1

Trials

8 trial(s) available for ruboxistaurin and Day Blindness

Article	Year
The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies. Investigative ophthalmology & visual science, 2013, Mar-11, Volume: 54, Issue:3 Topics: Administration, Oral; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Prospective Studies; Protein Kinase C; Protein Kinase C beta; Sickness Impact Profile; Surveys and Questionnaires; Tomography, Optical Coherence; Vision Disorders; Visual Acuity	2013
Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema. Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:1 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Severity of Illness Index; Time Factors; Vision Disorders; Vision Tests; Visual Acuity	2009
Sustained moderate visual loss as a predictive end point for visual loss in non-proliferative diabetic retinopathy. Eye (London, England), 2009, Volume: 23, Issue:1 Topics: Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Humans; Indoles; Maleimides; Treatment Outcome; Vision Disorders	2009
Diabetic macular oedema and visual loss: relationship to location, severity and duration. Acta ophthalmologica, 2009, Volume: 87, Issue:7 Topics: Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Indoles; Macula Lutea; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Severity of Illness Index; Time Factors; Vision Disorders; Visual Acuity	2009
Effect of ruboxistaurin (RBX) On visual acuity decline over a 6-year period with cessation and reinstitution of therapy: results of an open-label extension of the Protein Kinase C Diabetic Retinopathy Study 2 (PKC-DRS2). Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:6 Topics: Administration, Oral; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Male; Maleimides; Middle Aged; Protein Kinase C; Protein Kinase C beta; Retreatment; Vision Disorders; Vision Tests; Visual Acuity; Withholding Treatment	2011
Oral protein kinase c β inhibition using ruboxistaurin: efficacy, safety, and causes of vision loss among 813 patients (1,392 eyes) with diabetic retinopathy in the Protein Kinase C β Inhibitor-Diabetic Retinopathy Study and the Protein Kinase C β Inhibit Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:10 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Protein Kinase C beta; Treatment Outcome; Vision Disorders; Visual Acuity; Young Adult	2011
The effect of ruboxistaurin on visual loss in patients with moderately severe to very severe nonproliferative diabetic retinopathy: initial results of the Protein Kinase C beta Inhibitor Diabetic Retinopathy Study (PKC-DRS) multicenter randomized clinical Diabetes, 2005, Volume: 54, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Diabetic Retinopathy; Disease Progression; Enzyme Inhibitors; Female; Humans; Indoles; Male; Maleimides; Middle Aged; Patient Selection; Placebos; Protein Kinase C; Protein Kinase C beta; Treatment Outcome; Vision Disorders	2005
Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy. Ophthalmology, 2006, Volume: 113, Issue:12 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Diabetic Retinopathy; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Indoles; Macular Edema; Male; Maleimides; Middle Aged; Protein Kinase C; Protein Kinase C beta; Vision Disorders; Visual Acuity	2006

Other Studies

1 other study(ies) available for ruboxistaurin and Day Blindness

Article	Year
Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema. Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:12 Topics: Administration, Oral; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Enzyme Inhibitors; Humans; Indoles; Macular Edema; Maleimides; Protein Kinase C; Severity of Illness Index; Vision Disorders; Vision Tests; Visual Acuity	2010

Article

Year

Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema.

Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:12

Topics: Administration, Oral; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Enzyme Inhibitors; Humans; Indoles; Macular Edema; Maleimides; Protein Kinase C; Severity of Illness Index; Vision Disorders; Vision Tests; Visual Acuity

2010