Page last updated: 2024-09-04

ruboxistaurin and Chronic Disease

ruboxistaurin has been researched along with Chronic Disease in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	1 (25.00)	2.80

Authors

Authors	Studies
Ahmadian, R; Jernigan, NL; Resta, TC; Sheak, JR; Walker, BR; Weise-Cross, L; Yan, S	1
Shah, SV	1
Benson, C; Seger, M; Voelker, J	1
Shah, SV; Swaminathan, S	1

Reviews

2 review(s) available for ruboxistaurin and Chronic Disease

Article	Year
Progress toward novel treatments for chronic kidney disease. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2010, Volume: 20, Issue:5 Suppl Topics: Amides; Anticoagulants; Antihypertensive Agents; Bicarbonates; Chronic Disease; Enzyme Inhibitors; Fumarates; Glycosaminoglycans; Humans; Indoles; Iron Chelating Agents; Kidney Diseases; Kidney Failure, Chronic; Maleimides; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridones; Renin; Renin-Angiotensin System	2010
Novel approaches targeted toward oxidative stress for the treatment of chronic kidney disease. Current opinion in nephrology and hypertension, 2008, Volume: 17, Issue:2 Topics: Biomarkers; Chronic Disease; Diabetic Nephropathies; Disease Progression; Drugs, Investigational; Glycation End Products, Advanced; Humans; Indoles; Iron; Kidney; Kidney Diseases; Maleimides; Oxidative Stress; Protein Kinase C; Protein Kinase Inhibitors; Pyridoxamine; Reactive Oxygen Species; Treatment Outcome; Vitamin B Complex	2008

Article

Year

Progress toward novel treatments for chronic kidney disease.

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2010, Volume: 20, Issue:5 Suppl

Topics: Amides; Anticoagulants; Antihypertensive Agents; Bicarbonates; Chronic Disease; Enzyme Inhibitors; Fumarates; Glycosaminoglycans; Humans; Indoles; Iron Chelating Agents; Kidney Diseases; Kidney Failure, Chronic; Maleimides; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridones; Renin; Renin-Angiotensin System

2010

Novel approaches targeted toward oxidative stress for the treatment of chronic kidney disease.

Current opinion in nephrology and hypertension, 2008, Volume: 17, Issue:2

Topics: Biomarkers; Chronic Disease; Diabetic Nephropathies; Disease Progression; Drugs, Investigational; Glycation End Products, Advanced; Humans; Indoles; Iron; Kidney; Kidney Diseases; Maleimides; Oxidative Stress; Protein Kinase C; Protein Kinase Inhibitors; Pyridoxamine; Reactive Oxygen Species; Treatment Outcome; Vitamin B Complex

2008

Trials

1 trial(s) available for ruboxistaurin and Chronic Disease

Article	Year
Inhibition of PKC beta by ruboxistaurin does not enhance the acute blood pressure response to nitroglycerin. Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:2 Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Angina Pectoris; Blood Pressure; Chronic Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypotension, Orthostatic; Indoles; Infusions, Intravenous; Male; Maleimides; Middle Aged; Nitroglycerin; Protein Kinase C; Protein Kinase C beta; Treatment Outcome; Vasodilator Agents	2007

Article

Year

Inhibition of PKC beta by ruboxistaurin does not enhance the acute blood pressure response to nitroglycerin.

Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:2

Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Angina Pectoris; Blood Pressure; Chronic Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypotension, Orthostatic; Indoles; Infusions, Intravenous; Male; Maleimides; Middle Aged; Nitroglycerin; Protein Kinase C; Protein Kinase C beta; Treatment Outcome; Vasodilator Agents

2007

Other Studies

1 other study(ies) available for ruboxistaurin and Chronic Disease

Article	Year
PKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal rats. American journal of physiology. Heart and circulatory physiology, 2020, 02-01, Volume: 318, Issue:2 Topics: Animals; Animals, Newborn; Chronic Disease; Cyclic N-Oxides; Enzyme Inhibitors; Female; Free Radical Scavengers; Hypoxia; Indoles; Maleimides; Organophosphorus Compounds; Oxidative Stress; Pregnancy; Protein Kinase C beta; Pulmonary Artery; Pulmonary Circulation; Rats; Reactive Oxygen Species; Spin Labels; Ubiquinone; Vasoconstriction; Vasoconstrictor Agents	2020

Article

Year

PKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal rats.

American journal of physiology. Heart and circulatory physiology, 2020, 02-01, Volume: 318, Issue:2

Topics: Animals; Animals, Newborn; Chronic Disease; Cyclic N-Oxides; Enzyme Inhibitors; Female; Free Radical Scavengers; Hypoxia; Indoles; Maleimides; Organophosphorus Compounds; Oxidative Stress; Pregnancy; Protein Kinase C beta; Pulmonary Artery; Pulmonary Circulation; Rats; Reactive Oxygen Species; Spin Labels; Ubiquinone; Vasoconstriction; Vasoconstrictor Agents

2020