ruboxistaurin has been researched along with Cardiac Failure in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Houser, SR; Kranias, EG; Leitges, M; Liu, Q; Lorenz, JN; Macdonnell, SM; Molkentin, JD | 1 |
| Correll, RN; Hajjar, RJ; Houser, SR; Ishikawa, K; Kawase, Y; Ladage, D; Molkentin, JD; Tilemann, L | 1 |
| Belmonte, SL; Blaxall, BC | 1 |
| Bowling, N; Bristow, MR; Estridge, T; Fouts, RL; Gromo, G; King, GL; Mintze, K; Mizrahi, JL; Pickard, T; Roden, R; Sabbah, HN; Sandusky, GE; Song, G; Vlahos, CJ; Walsh, RA | 1 |
4 other study(ies) available for ruboxistaurin and Cardiac Failure
| Article | Year |
|---|---|
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Signaling; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Failure; Indoles; Maleimides; Metoprolol; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Infarction; Myocardium; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase Inhibitors; Pulmonary Edema; Time Factors | 2009 |
Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.
Topics: Animals; Cardiac Output; Coronary Occlusion; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heart; Heart Failure; Indoles; Maleimides; Myocardial Contraction; Myocardial Infarction; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Stroke Volume; Swine | 2011 |
PKC-ing is believing: targeting protein kinase C in heart failure.
Topics: Animals; Enzyme Inhibitors; Female; Heart Failure; Indoles; Maleimides; Myocardial Infarction; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha | 2011 |
Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart.
Topics: Adolescent; Adult; Calcium; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Heart Failure; Humans; Immunoenzyme Techniques; In Situ Hybridization; Indoles; Isoenzymes; Male; Maleimides; Middle Aged; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardium; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-epsilon; RNA, Messenger; Signal Transduction | 1999 |