rubitecan has been researched along with Breast Cancer in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Z; Giovanella, B; Harris, N; Kozielski, A; Stehlin, JS; Vardeman, D | 1 |
| Guiney, P; Haney, LG; Lenaz, L; Miller, KD; Murry, DJ; Sledge, GW; Soule, SE; Sun, SL | 1 |
| Cao, ZS; Dejesus, A; Giovanella, B; Mendoza, J | 1 |
| Chedid, S; Cristofanilli, M; Esteva, F; Frye, DK; Hortobagyi, G; Ibrahim, N; Mettinger, KL; Rivera, E; Valero, V | 1 |
| Early, JA; Giovanella, BC; Hinz, HR; Kozielski, AJ; Mendoza, JT; Pantazis, P | 1 |
| Gilbert, B; Giovanella, BC; Kleinerman, E; Knight, V; Koshkina, N; Waldrep, C | 1 |
2 trial(s) available for rubitecan and Breast Cancer
| Article | Year |
|---|---|
A phase II study of 9-nitro-camptothecin in patients with previously treated metastatic breast cancer.
Topics: Antineoplastic Agents; Area Under Curve; Breast Neoplasms; Camptothecin; Female; Humans; Metabolic Clearance Rate; Middle Aged; Neoplasm Metastasis | 2004 |
Minimal clinical benefit of single agent Orathecin (Rubitecan) in heavily pretreated metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Disease Progression; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Prospective Studies; Treatment Outcome | 2006 |
4 other study(ies) available for rubitecan and Breast Cancer
| Article | Year |
|---|---|
Alkyl esters of camptothecin and 9-nitrocamptothecin: synthesis, in vitro pharmacokinetics, toxicity, and antitumor activity.
Topics: Acylation; Alkylation; Animals; Antineoplastic Agents; Breast Neoplasms; Camptothecin; Female; Humans; Mice; Mice, Nude; Molecular Structure; Structure-Activity Relationship; Transplantation, Heterologous | 1998 |
Synthesis and anti-tumor activity of alkenyl camptothecin esters.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Esters; Humans; Inhibitory Concentration 50; Mice; Molecular Structure; Neoplasm Transplantation | 2005 |
Regression of human breast carcinoma tumors in immunodeficient mice treated with 9-nitrocamptothecin: differential response of nontumorigenic and tumorigenic human breast cells in vitro.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Division; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; In Vitro Techniques; Mice; Mice, Nude; Tumor Cells, Cultured | 1993 |
Anti-cancer activity of 9-nitrocamptothecin liposome aerosol in mice.
Topics: Aerosols; Animals; Antineoplastic Agents; Breast Neoplasms; Camptothecin; Female; Humans; Liposomes; Lung Neoplasms; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Particle Size; Transplantation, Heterologous | 2000 |