rtki cpd has been researched along with Lung Neoplasms in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Akudugu, JM; Hamid, MB; Serafin, AM | 1 |
| Chen, L; Chen, X; Huang, H; Huang, Z; Li, Y; Ye, X; Yu, N | 1 |
| Arai, W; Chiba, H; Kodera, Y; Kohno, T; Kojima, T; Konno, T; Miyajima, M; Sakuma, Y; Shindo, Y; Tsujiwaki, M; Watanabe, A | 1 |
| Gao, FH; Guo, YH; Jiang, B; Shi, J; Yuan, HH | 1 |
| Gong, XD; Guo, YH; Jiang, B; Shi, J; Wang, JY; Yuan, HH | 1 |
| Harada, H; Kojima, S; Takai, E; Tsukimoto, M | 1 |
| Ito, F; Nishio, K; Shin-ya, T; Takeuchi, K | 1 |
| Ishigatsubo, Y; Kaneko, T; Kuroda, H; Miyazawa, N; Murakami, S; Takeno, M | 1 |
| Bowman, ED; Croce, CM; Gemma, A; Goto, A; Harris, CC; Horikawa, I; Jen, J; Kudoh, S; Mathe, EA; Okano, T; Schetter, AJ; Seike, M; Sugimura, H; Yang, P | 1 |
| Chiba, M; Fujiwara, M; Goya, T; Kishino, T; Matsushima, S; Morii, T; Ogura, W; Ohnishi, H; Ohtsuka, K; Watanabe, T | 1 |
| Ikari, A; Sato, T; Sugatani, J; Watanabe, R; Yamazaki, Y | 1 |
| Koty, PP; Lei, W; Levitt, ML | 1 |
| Ishii, T; Masuda, M; Matsuse, T; Teramoto, S | 1 |
| Carbone, DP; Dang, TP; Eichenberger, S; Gonzalez, A; Haruki, N; Kawaguchi, KS; Massion, PP; Olson, S | 1 |
| Hur, GY; In, KH; Jung, HC; Jung, KH; Kang, EJ; Kang, KH; Kim, JH; Lee, SY; Shim, JJ; Shin, C; Yoo, SH | 1 |
| Aburatani, H; Fukayama, M; Goto, A; Ishikawa, S; Morikawa, T; Nakajima, J; Nakamura, Y; Niki, T; Ohara, E; Ota, S; Wang, T | 1 |
| Banville, M; Bourget, L; Collins, C; Jaramillo, ML; O'Connor-McCourt, M; Paul-Roc, B | 1 |
| Böhmer, FD; Fernández, LE; Greiser, U; Lage, A; Perez, R; Sánchez, B; Suarez Pestana, E | 1 |
| Klein, JM; McCarthy, TA | 1 |
19 other study(ies) available for rtki cpd and Lung Neoplasms
| Article | Year |
|---|---|
Selective therapeutic benefit of X-rays and inhibitors of EGFR, PI3K/mTOR, and Bcl-2 in breast, lung, and cervical cancer cells.
Topics: Aniline Compounds; Breast Neoplasms; Cell Line; Cell Survival; ErbB Receptors; Female; Humans; Imidazoles; Lung Neoplasms; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Quinolines; Radiation Tolerance; Sulfonamides; TOR Serine-Threonine Kinases; Tyrphostins; Uterine Cervical Neoplasms; X-Rays | 2021 |
PAR2 promotes tumor-associated angiogenesis in lung adenocarcinoma through activating EGFR pathway.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Neovascularization, Pathologic; Receptor, PAR-2; Vascular Endothelial Growth Factor A | 2022 |
Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Claudin-2; Down-Regulation; Epidermal Growth Factor; Humans; Lung Neoplasms; Tight Junctions; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2023 |
[EGFR-ERK signaling pathway down-regulates miRNA-145 in lung cancer cells].
Topics: Butadienes; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Quinazolines; Tyrphostins | 2013 |
[Effects of AG1478 on the expression of FOXM1 gene via FOXO3a in non-small cell lung cancer cells].
Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; ErbB Receptors; Forkhead Box Protein M1; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Lung Neoplasms; Quinazolines; RNA, Messenger; RNA, Small Interfering; Transfection; Tyrphostins | 2013 |
Autocrine signaling via release of ATP and activation of P2X7 receptor influences motile activity of human lung cancer cells.
Topics: Adenosine Triphosphate; Autocrine Communication; Cell Line, Tumor; Cell Movement; Humans; Lung Neoplasms; Quinazolines; Receptors, Purinergic P2X7; Tyrphostins | 2014 |
Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dual Specificity Phosphatase 1; ErbB Receptors; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mice; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Tyrphostins | 2009 |
Inhibition of heme oxygenase-1 with an epidermal growth factor receptor inhibitor and cisplatin decreases proliferation of lung cancer A549 cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; ErbB Receptors; Heme Oxygenase-1; Humans; Lung Neoplasms; Protein Kinase Inhibitors; Quinazolines; RNA, Small Interfering; Tyrphostins | 2010 |
MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers.
Topics: Adult; Aged; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; MicroRNAs; Middle Aged; Mutation; Quinazolines; RNA, Antisense; Signal Transduction; Smoking; Tyrphostins | 2009 |
Downregulated ABCG2 enhances sensitivity to topoisomerase I inhibitor in epidermal growth factor receptor tyrosine kinase inhibitor-resistant non-small cell lung cancer.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; DNA Topoisomerases, Type I; DNA, Neoplasm; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Genotype; Humans; Lung Neoplasms; Mutation; Neoplasm Proteins; Polymerase Chain Reaction; Protein Tyrosine Phosphatases; Quinazolines; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tyrphostins | 2010 |
Increase in claudin-2 expression by an EGFR/MEK/ERK/c-Fos pathway in lung adenocarcinoma A549 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Binding Sites; Butadienes; Cell Line, Tumor; Claudins; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; MAP Kinase Signaling System; Nitriles; Promoter Regions, Genetic; Protease Inhibitors; Protein Binding; Proto-Oncogene Proteins c-fos; Quinazolines; RNA, Messenger; RNA, Small Interfering; Transcription Factor AP-1; Tyrphostins | 2012 |
Relationship of EGFR signal-transduction modulation by tyrosine kinase inhibitors to chemosensitivity and programmed cell death in lung cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Lung Neoplasms; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Quinazolines; Signal Transduction; Tumor Cells, Cultured; Tyrphostins | 2003 |
The effects of S-phase kinase-associated protein 2 (SKP2) on cell cycle status, viability, and chemoresistance in A549 lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Quinazolines; S-Phase Kinase-Associated Proteins; Tyrphostins | 2004 |
Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers.
Topics: Apoptosis; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Down-Regulation; Dual Specificity Phosphatase 1; Enzyme Inhibitors; ErbB Receptors; Humans; Immediate-Early Proteins; Lung Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Quinazolines; Receptor, Notch3; Receptors, Cell Surface; Receptors, Notch; Transfection; Tyrphostins | 2005 |
Peroxisome proliferator-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells.
Topics: Carcinoma, Mucoepidermoid; Cell Line, Tumor; Down-Regulation; Enzyme Inhibitors; ErbB Receptors; Humans; Hypoglycemic Agents; Lung Neoplasms; Mucin 5AC; Mucins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Respiratory Mucosa; Rosiglitazone; Smoking; Thiazolidinediones; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins | 2006 |
Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway.
Topics: Adenocarcinoma; Cell Adhesion; Cell Hypoxia; Cell Line, Tumor; Cell Movement; ErbB Receptors; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Quinazolines; Signal Transduction; Tyrphostins | 2007 |
Differential sensitivity of A549 non-small lung carcinoma cell responses to epidermal growth factor receptor pathway inhibitors.
Topics: Antibodies, Blocking; Antineoplastic Agents; Biological Assay; Carcinoma, Non-Small-Cell Lung; Cell Movement; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Tyrphostins | 2008 |
Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s).
Topics: Adenocarcinoma; Benzylidene Compounds; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Membrane; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; G(M3) Ganglioside; Humans; Lung Neoplasms; Nitriles; Phosphorylation; Protein Tyrosine Phosphatases; Quinazolines; Radioligand Assay; Signal Transduction; Tumor Cells, Cultured; Tyrphostins | 1997 |
Inhibition of tyrosine kinase activity decreases expression of surfactant protein A in a human lung adenocarcinoma cell line independent of epidermal growth factor receptor.
Topics: Benzylidene Compounds; Binding, Competitive; Blotting, Northern; Blotting, Western; Cell Survival; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Isoflavones; Lung; Lung Neoplasms; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Quinazolines; RNA, Messenger; Tumor Cells, Cultured; Tyrphostins | 1997 |