Compounds > rtki cpd

rtki cpd and Breast Neoplasms

rtki cpd has been researched along with Breast Neoplasms in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.00)18.2507
2000's19 (47.50)29.6817
2010's18 (45.00)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Akudugu, JM; Hamid, MB; Serafin, AM1
Fu, S; Li, P; Li, ZB; Veldwijk, MR; Xu, WC; Zhang, Q1
Buttitta, G; Carlisi, D; D'Anneo, A; Di Fiore, R; Emanuele, S; Lauricella, M; Tesoriere, G; Vento, R1
Chen, C; Gao, Z; Kang, H; Li, J; Rong, G; Zhang, L; Zhang, X1
Bal de Kier Joffé, E; Pontiggia, O; Raffo, D; Simian, M1
Denny, EC; Kane, SE1
Chang, FR; Chen, IH; Hsieh, PW; Shih, HC; Wu, CC; Wu, YC1
Fukuda, T; Gu, J; Hang, Q; Hou, S; Im, S; Isaji, T1
Sui, JQ; Xie, KP; Xie, MJ1
Chen, G; Hossain, MM; Hu, B; Meng, X; Sun, Y; Zhang, X1
Calleja, V; Harris, A; Kong, A; Larijani, B; Leboucher, P; Parker, PJ1
Du, Q; Fang, WG; Jin, ML; Tian, XX; Zhang, YG1
Ahidouch, A; El Hiani, Y; Lehen'kyi, V; Ouadid-Ahidouch, H1
Cho, S; Choe, JH; Choi, JH; Kim, JH; Kim, JS; Kim, S; Kim, WW; Lee, JE; Lee, SK; Lim, HI; Nam, SJ; Yang, JH1
El Debs, BW; Griffiths, AD; Merten, CA; Tschulena, U1
Fang, Y; Shi, X; Tan, Y; Wang, X; Zhang, M; Zhang, W1
Grandal, MV; Grøvdal, LM; Holst, MR; Kim, J; Knudsen, SL; van Deurs, B1
Deng, Z; Du, WW; Fang, L; Jeyapalan, Z; Seth, A; Shan, SW; Yang, BB; Yang, BL; Yee, AJ; Zhang, Y1
Fu, S; Li, P; Li, ZB; Lu, B; Torossian, A; Xu, WC; Zhang, Q1
Fu, S; Li, P; Torossian, A; Xu, WC; Zhang, Q1
Bissell, MJ; Furuta, S; Kenny, PA; Lee, SY; Lenburg, ME; Meier, R; Xu, R1
Abrams, SL; Candido, S; Cervello, M; Chappell, WH; Franklin, RA; LaHair, MM; Libra, M; Martelli, AM; McCubrey, JA; Milella, M; Montalto, G; Nicoletti, F; Polesel, J; Steelman, LS; Tafuri, A; Talamini, R1
Afratis, N; Ellina, MI; Gialeli, C; Karamanos, NK; Piperigkou, Z; Skandalis, SS; Theocharis, AD; Tsonis, AI; Tzanakakis, GN1
Levin, ER; Park, ST; Pedram, A; Razandi, M1
Chen, X; Pennock, S; Wang, Y; Wang, Z1
González, A; Guerrero, J; Martínez, J; Santibañez, JF1
Chen, L; Gao, P; Ma, D; Oppenheim, JJ; Sun, R; Wang, J; Zhang, N1
Chan, CT; Kane, SE; Metz, MZ1
Lipscomb, EA; Shin, S; Yoon, SO1
Brown, KA; Emlet, DR; Pollice, AA; Schwartz, R; Shackney, SE; Smith, CA1
Wang, XY; Wu, ZY; Zhen, LL; Zheng, W; Zhu, X1
Gaiger, A; Grunt, TW; Kainz, B; Köhler, G; Puckmair, K; Rünzler, D; Tomek, K; Wagner, R; Zielinski, CC1
Bao, J; Davis, SR; Lipkowitz, S; Meltzer, PS; Nau, MM; Pumphrey, JG; Rahman, M1
Chen, PB; Contessa, JN; Dent, P; Kavanagh, BD; Mikkelsen, RB; Rorrer, WK; Schmidt-Ullrich, RK; Todd, DG; Valerie, K1
Allal, C; Asslan, R; Favre, G; Le Gaillard, F; Pradines, A; Pratx, C1
Bates, SE; Bishop, PC; Blagosklonny, MV; Fojo, T; Robey, R1
Brattain, MG; Jackson, JG; Koterba, AP; Kreisberg, JI; Yee, D1
Arteaga, CL; Forbes, JT; Kurokawa, H; Lenferink, AE; Pisacane, PI; Simpson, JF; Sliwkowski, MX1
Amir, C; Bowers, G; Dent, P; Hewitt, T; Lammering, G; Mikkelsen, RB; Reardon, D; Schmidt-Ullrich, RK; Valerie, K1
Arteaga, CL; Busse, D; Flanagan, WM; Lenferink, AE; Yakes, FM1

Reviews

1 review(s) available for rtki cpd and Breast Neoplasms

ArticleYear
The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells.
    Oncogene, 2001, Mar-15, Volume: 20, Issue:11

    Topics: Autocrine Communication; Benzothiazoles; Breast Neoplasms; Carcinoma; Epidermal Growth Factor; ErbB Receptors; Female; Genes, erbB; Growth Substances; Humans; Neuregulin-1; Quinazolines; Radiation, Ionizing; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; Signal Transduction; Tumor Cells, Cultured; Tyrphostins

2001

Other Studies

39 other study(ies) available for rtki cpd and Breast Neoplasms

ArticleYear
Selective therapeutic benefit of X-rays and inhibitors of EGFR, PI3K/mTOR, and Bcl-2 in breast, lung, and cervical cancer cells.
    European journal of pharmacology, 2021, Dec-05, Volume: 912

    Topics: Aniline Compounds; Breast Neoplasms; Cell Line; Cell Survival; ErbB Receptors; Female; Humans; Imidazoles; Lung Neoplasms; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Quinolines; Radiation Tolerance; Sulfonamides; TOR Serine-Threonine Kinases; Tyrphostins; Uterine Cervical Neoplasms; X-Rays

2021
Co-inhibition of epidermal growth factor receptor and insulin-like growth factor receptor 1 enhances radiosensitivity in human breast cancer cells.
    BMC cancer, 2013, Jun-19, Volume: 13

    Topics: Analysis of Variance; Animals; Apoptosis; Breast Neoplasms; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Female; G1 Phase Cell Cycle Checkpoints; Humans; MAP Kinase Signaling System; MCF-7 Cells; Mice; Mice, Nude; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Radiation Tolerance; Receptor, IGF Type 1; Tumor Stem Cell Assay; Tyrphostins

2013
Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells.
    International journal of oncology, 2013, Volume: 43, Issue:6

    Topics: Acetophenones; Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors; Female; Humans; NADPH Oxidases; NF-kappa B; Phosphorylation; Protein Tyrosine Phosphatases; Quinazolines; Sesquiterpenes; Superoxides; Tyrphostins

2013
Dual inhibition of EGFR at protein and activity level via combinatorial blocking of PI4KIIα as anti-tumor strategy.
    Protein & cell, 2014, Volume: 5, Issue:6

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; ErbB Receptors; Female; HSP90 Heat-Shock Proteins; Humans; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Minor Histocompatibility Antigens; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Quinazolines; Transplantation, Heterologous; Tyrphostins

2014
Non-genomic actions of estradiol and 4-OH-tamoxifen on murine breast cancer cells.
    Oncology reports, 2015, Volume: 33, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Humans; MCF-7 Cells; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Tamoxifen; Tyrphostins

2015
t-Darpp Promotes Enhanced EGFR Activation and New Drug Synergies in Her2-Positive Breast Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Humans; Quinazolines; Receptor, ErbB-2; Trastuzumab; Tyrphostins

2015
HPW-RX40 restores anoikis sensitivity of human breast cancer cells by inhibiting integrin/FAK signaling.
    Toxicology and applied pharmacology, 2015, Dec-01, Volume: 289, Issue:2

    Topics: Anoikis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Adhesion; Cell Aggregation; Cell Line, Tumor; Chlorobenzoates; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Female; Focal Adhesion Kinase 1; Humans; Integrin beta1; Paxillin; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; src-Family Kinases; Styrenes; Tyrphostins

2015
Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells.
    Scientific reports, 2016, Jan-05, Volume: 6

    Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; ErbB Receptors; Female; Gene Deletion; Gene Expression; Gene Knockout Techniques; Humans; Integrin beta1; Protein Kinase Inhibitors; Protein Subunits; Quinazolines; Signal Transduction; Tyrphostins

2016
Inhibitory effect of luteolin on the proliferation of human breast cancer cell lines induced by epidermal growth factor.
    Sheng li xue bao : [Acta physiologica Sinica], 2016, Feb-25, Volume: 68, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromones; Epidermal Growth Factor; ErbB Receptors; Humans; Luteolin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphatidylinositol 3-Kinases; Quinazolines; Tyrphostins

2016
ADAM17-siRNA inhibits MCF-7 breast cancer through EGFR-PI3K-AKT activation.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: ADAM17 Protein; Animals; Benzamides; Breast Neoplasms; Chromones; Diphenylamine; ErbB Receptors; Female; Humans; MCF-7 Cells; Mice; Morpholines; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; RNA, Small Interfering; Signal Transduction; Tyrphostins; Xenograft Model Antitumor Assays

2016
HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.
    PloS one, 2008, Aug-06, Volume: 3, Issue:8

    Topics: Betacellulin; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; ErbB Receptors; Female; Genes, erbB-2; Humans; Intercellular Signaling Peptides and Proteins; Neuregulin-1; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-4; Tyrphostins

2008
Tyrphostin AG1478 suppresses proliferation and invasion of human breast cancer cells.
    International journal of oncology, 2008, Volume: 33, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; ErbB Receptors; Female; Flow Cytometry; Gene Expression; Humans; Matrix Metalloproteinase 9; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Telomerase; Tyrphostins

2008
Activation of the calcium-sensing receptor by high calcium induced breast cancer cell proliferation and TRPC1 cation channel over-expression potentially through EGFR pathways.
    Archives of biochemistry and biophysics, 2009, Jun-01, Volume: 486, Issue:1

    Topics: Base Sequence; Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Dipeptides; DNA Primers; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Quinazolines; Receptors, Calcium-Sensing; Transcriptional Activation; TRPC Cation Channels; Tyrphostins

2009
EGF-induced MMP-9 expression is mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line.
    Cellular signalling, 2009, Volume: 21, Issue:6

    Topics: Breast Neoplasms; Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Matrix Metalloproteinase 9; Phosphorylation; Quinazolines; RNA, Messenger; RNA, Small Interfering; STAT3 Transcription Factor; Tyrphostins

2009
A competitive co-cultivation assay for cancer drug specificity evaluation.
    Journal of biomolecular screening, 2011, Volume: 16, Issue:8

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorescence; High-Throughput Screening Assays; Humans; Indoles; Kidney Neoplasms; Organ Specificity; Quinazolines; Reproducibility of Results; Sodium Azide; Sulfonamides; Tyrphostins

2011
Effect of bisphenol A on the EGFR-STAT3 pathway in MCF-7 breast cancer cells.
    Molecular medicine reports, 2012, Volume: 5, Issue:1

    Topics: Benzhydryl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Phenols; Quinazolines; RNA Interference; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Time Factors; Tyrphostins

2012
EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells.
    Cellular signalling, 2012, Volume: 24, Issue:1

    Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Chromones; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gene Expression; Gene Expression Profiling; Humans; Imidazoles; MAP Kinase Kinase 1; Morpholines; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; RNA, Messenger; Signal Transduction; Tyrphostins; Up-Regulation

2012
Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Animals; Anthracenes; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Survival; Docetaxel; Doxorubicin; Epirubicin; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Green Fluorescent Proteins; Humans; Mice; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sphingosine; Taxoids; Tyrphostins; Versicans

2011
Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer.
    International journal of radiation oncology, biology, physics, 2012, Jul-01, Volume: 83, Issue:3

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chromones; ErbB Receptors; Female; G1 Phase; Humans; Mice; Mice, Nude; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Radiation Tolerance; Radiation-Sensitizing Agents; Random Allocation; Resting Phase, Cell Cycle; Tyrphostins

2012
Inhibition of phosphoinositide 3-kinase enhances the cytotoxicity of AG1478, an epidermal growth factor receptor inhibitor, in breast cancer cells.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromones; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Female; Flow Cytometry; Humans; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Tyrphostins

2012
FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:9

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Gene Knockdown Techniques; Humans; Kaplan-Meier Estimate; Lapatinib; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-raf; Quinazolines; RNA Interference; Signal Transduction; Tyrphostins; Xenograft Model Antitumor Assays

2012
Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.
    Cell cycle (Georgetown, Tex.), 2012, Dec-01, Volume: 11, Issue:23

    Topics: Acute-Phase Proteins; Antibiotics, Antineoplastic; Benzylamines; Berberine; Biphenyl Compounds; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression; HT29 Cells; Humans; Lipocalin-2; Lipocalins; MCF-7 Cells; Nitrophenols; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Sirolimus; Sulfonamides; Tyrphostins

2012
Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells.
    The FEBS journal, 2013, Volume: 280, Issue:10

    Topics: Breast Neoplasms; Cell Movement; ErbB Receptors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation; Glypicans; Humans; Insulin-Like Growth Factor I; MCF-7 Cells; Quinazolines; Receptor Cross-Talk; Signal Transduction; Syndecan-2; Syndecan-4; Tyrphostins

2013
Proximal events in signaling by plasma membrane estrogen receptors.
    The Journal of biological chemistry, 2003, Jan-24, Volume: 278, Issue:4

    Topics: Animals; Breast Neoplasms; Cattle; Cell Membrane; Cells, Cultured; Dipeptides; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Heterotrimeric GTP-Binding Proteins; Humans; Ligands; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinases; Models, Biological; Oligonucleotides, Antisense; Protease Inhibitors; Protein Binding; Protein Structure, Tertiary; Quinazolines; Receptors, Estrogen; Signal Transduction; Structure-Activity Relationship; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tyrphostins

2003
Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor.
    Science's STKE : signal transduction knowledge environment, 2002, Dec-03, Volume: 2002, Issue:161

    Topics: Animals; Breast Neoplasms; Cell Line; Dogs; Endosomes; ErbB Receptors; Fluorescent Antibody Technique, Indirect; Humans; Kidney; Membrane Proteins; Mice; Monensin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Quinazolines; Signal Transduction; Tumor Cells, Cultured; Tyrphostins

2002
EGF receptor transactivation by urokinase receptor stimulus through a mechanism involving Src and matrix metalloproteinases.
    Experimental cell research, 2004, Jan-01, Volume: 292, Issue:1

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; ErbB Receptors; Female; Genes, src; Humans; Kinetics; Matrix Metalloproteinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Peptide Fragments; Phosphorylation; Quinazolines; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Transcriptional Activation; Tyrphostins; Urokinase-Type Plasminogen Activator

2004
Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.
    Cancer research, 2005, Feb-15, Volume: 65, Issue:4

    Topics: Alkaloids; Benzophenanthridines; Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Chemokines, CXC; Chemotaxis; Chromones; Epidermal Growth Factor; ErbB Receptors; Humans; Morpholines; Phenanthridines; Protein Kinase C; Protein Kinase Inhibitors; Quinazolines; Tyrphostins

2005
Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors.
    Breast cancer research and treatment, 2005, Volume: 91, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromones; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Signal Transduction; Trastuzumab; Tumor Cells, Cultured; Tyrphostins

2005
A novel mechanism for integrin-mediated ras activation in breast carcinoma cells: the alpha6beta4 integrin regulates ErbB2 translation and transactivates epidermal growth factor receptor/ErbB2 signaling.
    Cancer research, 2006, Mar-01, Volume: 66, Issue:5

    Topics: Breast Neoplasms; Cell Line, Tumor; ErbB Receptors; Eukaryotic Initiation Factor-4E; Humans; Integrin alpha6beta4; Neoplasm Invasiveness; Phosphorylation; Protein Biosynthesis; Quinazolines; ras Proteins; Receptor, ErbB-2; RNA, Small Interfering; Signal Transduction; Transcriptional Activation; Transfection; Tyrphostins

2006
HER2 expression as a potential marker for response to therapy targeted to the EGFR.
    British journal of cancer, 2006, Apr-24, Volume: 94, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Laser Scanning Cytometry; Mitogen-Activated Protein Kinases; Phosphorylation; Predictive Value of Tests; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Sensitivity and Specificity; Structure-Activity Relationship; Trastuzumab; Tyrphostins

2006
[Involvement of epidermal growth factor receptor signaling pathway in tamoxifen resistance of MCF-7 cells].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:7

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Quinazolines; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Tamoxifen; Tyrphostins

2006
Upregulation of retinoic acid receptor-beta by the epidermal growth factor-receptor inhibitor PD153035 is not mediated by blockade of ErbB pathways.
    Journal of cellular physiology, 2007, Volume: 211, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line, Tumor; CpG Islands; DNA Methylation; Enzyme Inhibitors; ErbB Receptors; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Quinazolines; Receptors, Retinoic Acid; RNA Processing, Post-Transcriptional; Transcription, Genetic; Tyrphostins; Up-Regulation

2007
TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype.
    Breast cancer research and treatment, 2009, Volume: 113, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Epithelium; ErbB Receptors; Female; Genes, erbB-2; Humans; Mesoderm; Neoplasm Proteins; Phenotype; Protein Kinase Inhibitors; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Fusion Proteins; RNA Interference; Tyrphostins

2009
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation.
    Oncogene, 1997, Sep-04, Volume: 15, Issue:10

    Topics: Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Division; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Nitriles; Phospholipase C gamma; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Quinazolines; Radiation, Ionizing; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins

1997
Epidermal growth factor stimulates 3-hydroxy-3-methylglutaryl-coenzyme A reductase expression via the ErbB-2 pathway in human breast adenocarcinoma cells.
    Biochemical and biophysical research communications, 1999, Jul-14, Volume: 260, Issue:3

    Topics: Adenocarcinoma; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Epidermal Growth Factor; ErbB Receptors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Receptor, ErbB-2; Signal Transduction; Tumor Cells, Cultured; Tyrphostins

1999
Loss of cell cycle control allows selective microtubule-active drug-induced Bcl-2 phosphorylation and cytotoxicity in autonomous cancer cells.
    Cancer research, 2000, Jul-01, Volume: 60, Issue:13

    Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Cell Survival; Enzyme Inhibitors; Epidermal Growth Factor; Female; HL-60 Cells; Humans; Microtubules; Mitosis; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured; Tyrphostins

2000
Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.
    Oncogene, 2000, Sep-21, Volume: 19, Issue:40

    Topics: Alkaline Phosphatase; Biological Transport; Breast Neoplasms; Cell Nucleus; Chromones; Cytoplasm; DNA-Binding Proteins; Epidermal Growth Factor; ErbB Receptors; Female; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Macromolecular Substances; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-cbl; Quinazolines; Signal Transduction; Transcription Factors; Tumor Cells, Cultured; Tyrphostins; Ubiquitin-Protein Ligases

2000
Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells.
    Cancer research, 2000, Oct-15, Volume: 60, Issue:20

    Topics: Animals; Breast Neoplasms; Butadienes; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Gene Expression; Humans; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Tamoxifen; Transcription, Genetic; Tyrphostins; Xenograft Model Antitumor Assays

2000
ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Cancer research, 2001, Sep-01, Volume: 61, Issue:17

    Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Activation; Enzyme Inhibitors; G1 Phase; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Signal Transduction; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrphostins; Up-Regulation

2001