rtki cpd has been researched along with Astrocytoma, Grade IV in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bambini, V; Brunetto, AT; de Farias, CB; Freire, NH; Jaeger, M; Metcalfe, VA; Pinheiro, KV; Roesler, R; Shaw, L; Smith, CGS; Souza, BK; Thomaz, A | 1 |
| Han, D; Sun, J; Wang, F; Xiao, W; Zhu, Y | 1 |
| Ayuso-Sacido, A; Boockvar, JA; García-Verdugo, JM; Holland, EC; Kapoor, GS; Kratovac, S; Moliterno, JA; O'Rourke, DM; Roy, NS | 1 |
| Beyene, RT; Bleau, AM; Boockvar, JA; Gursel, DB; Holland, EC; Howard, BM | 1 |
| Bulfone, A; Cominelli, M; De Palma, M; Falini, A; Franzin, A; Galli, R; Mazzoleni, S; Pala, M; Poliani, PL; Politi, LS; Sergi Sergi, L | 1 |
| Berezowska, S; Brockhoff, G; Busch, R; Diermeier-Daucher, S; Duyster, J; Grosu, AL; Schlegel, J | 1 |
| Carrasco-García, E; Conde, M; Ferragut, JA; García-Morales, P; Gómez-Martínez, A; Grasso, S; Martínez-Lacaci, I; Rocamora-Reverte, L; Saceda, M | 1 |
| Berezin, V; Pedersen, MW; Pedersen, N; Poulsen, HS; Tkach, V | 1 |
| Abulrob, A; Andrade, MF; Giuseppin, S; McDermid, A; Moreno, M; Stanimirovic, D | 1 |
| Bigner, DD; Kwatra, MM; Richardson, MD; Yamaguchi, K | 1 |
| Burgess, AW; Doherty, MM; Ellis, AG; Johns, TG; Levitzki, A; McLachlan, G; Murphy, R; Nerrie, M; Nice, EC; Scott, AM; Vitali, A; Walker, F; Webster, LK; Weinstock, J | 1 |
| Cavenee, WK; Gazit, A; Huang, HJ; Levitzki, A; Nagane, M | 1 |
| Burgess, AW; Cavenee, WK; Huang, HJ; Levitzki, A; Mishima, K; Nagane, M; Narita, Y | 1 |
| Chakravarti, A; Dyson, NJ; Loeffler, JS | 1 |
| Archer, GE; Friedman, HS; Glazer, CA; Lal, A; Martinson, HM; Riggins, GJ; Sampson, JH | 1 |
15 other study(ies) available for rtki cpd and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Expression and pharmacological inhibition of TrkB and EGFR in glioblastoma.
Topics: Animals; Antineoplastic Agents; Azepines; Benzamides; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Glioblastoma; Humans; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Grading; Protein Kinase Inhibitors; Quinazolines; Receptor, trkB; Tyrphostins; Xenograft Model Antitumor Assays | 2020 |
MiRNA-181c inhibits EGFR-signaling-dependent MMP9 activation via suppressing Akt phosphorylation in glioblastoma.
Topics: Blotting, Western; Cell Line, Tumor; Chromones; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Matrix Metalloproteinase 9; MicroRNAs; Models, Genetic; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tyrphostins | 2014 |
Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioblastoma; Green Fluorescent Proteins; Humans; Mutation; Nerve Tissue Proteins; Neurons; Oxidative Stress; Quinazolines; Signal Transduction; Stem Cells; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrphostins | 2010 |
EGFR signaling is differentially activated in patient-derived glioblastoma stem cells.
Topics: Cell Line, Tumor; ErbB Receptors; Erlotinib Hydrochloride; Glioblastoma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Signal Transduction; Tyrphostins | 2010 |
Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; ErbB Receptors; Gene Silencing; Gene Transfer Techniques; Glioblastoma; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Quinazolines; RNA, Messenger; Tyrphostins | 2010 |
Effect of additional inhibition of human epidermal growth factor receptor 2 with the bispecific tyrosine kinase inhibitor AEE788 on the resistance to specific EGFR inhibition in glioma cells.
Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Glioblastoma; Humans; Protein Kinase Inhibitors; Purines; Quinazolines; Receptor, ErbB-2; Tyrphostins | 2010 |
Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines.
Topics: Blotting, Western; Cell Proliferation; Enzyme Inhibitors; ErbB Receptors; Flow Cytometry; Glioblastoma; Humans; Immunoprecipitation; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-3; Receptor, ErbB-4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured; Tyrphostins | 2011 |
Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Movement; Enzyme Inhibitors; ErbB Receptors; Fibroblasts; Glioblastoma; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Receptor Protein-Tyrosine Kinases; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins | 2004 |
Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae.
Topics: Caveolin 1; Caveolins; Cell Division; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Phosphorylation; Quinazolines; Tyrosine; Tyrphostins | 2004 |
Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta.
Topics: Acetophenones; Benzopyrans; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Intracellular Signaling Peptides and Proteins; Oligonucleotides, Antisense; Phosphorylation; Protein Kinase C-delta; Pyrimidines; Quinazolines; Receptors, Neurokinin-1; RNA, Small Interfering; Signal Transduction; Tyrphostins | 2005 |
Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase.
Topics: Animals; Area Under Curve; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; ErbB Receptors; Glioblastoma; Humans; Injections, Intravenous; Injections, Subcutaneous; Mice; Molecular Structure; Protein Tyrosine Phosphatases; Quinazolines; Rats; Thymidine; Tyrphostins; Xenograft Model Antitumor Assays | 2006 |
Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Caspase 3; Caspases; Cisplatin; Cysteine Endopeptidases; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; ErbB Receptors; Glioblastoma; Humans; Nitriles; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Tumor Cells, Cultured; Tyrphostins | 1998 |
Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor.
Topics: Animals; Brain Neoplasms; Cell Survival; Cisplatin; Enzyme Inhibitors; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Transplantation; Protein Tyrosine Phosphatases; Quinazolines; Transplantation, Heterologous; Tumor Cells, Cultured; Tyrphostins | 2001 |
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling.
Topics: Apoptosis; Arabidopsis Proteins; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Glioblastoma; Humans; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Plant Proteins; Potassium Channels; Quinazolines; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases; Signal Transduction; Tumor Cells, Cultured; Tyrphostins | 2002 |
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
Topics: Animals; Enzyme Inhibitors; ErbB Receptors; Extracellular Matrix Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Metalloendopeptidases; Mice; Mice, Nude; Neoplasm Invasiveness; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Serine Endopeptidases; Transfection; Tumor Cells, Cultured; Tyrphostins; Up-Regulation | 2002 |