rti-113 has been researched along with Substance-Related-Disorders* in 1 studies
1 other study(ies) available for rti-113 and Substance-Related-Disorders
Article | Year |
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RTI-113 administration reduces cocaine self-administration at high occupancy of dopamine transporter.
RTI-113 [3beta-(4-chlorophenyl)tropan-2beta carboxylic acid phenyl ester hydrochloride], one of many phenyltropanes potent at and selective for DAT, inhibited self-administration of cocaine in rat at doses that did not alter responding maintained by food. The doses that inhibited cocaine intake produced significant levels of occupancy of DAT. Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Rats; Rats, Inbred F344; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1998 |