rp 73401 has been researched along with Disease Models, Animal in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Alonso, JM; Andrés, JI; Boeckx, G; Cools, M; de Chaffoy, D; De Clerck, F; Deroose, F; Díaz, A; Diels, G; Fernández, J; Freyne, EJ; Iturrino, L; Martínez, P; Matesanz, E; Megens, A; Peeters, D; Petit, D; Somers, M; Stoppie, P; Van Wauwe, J | 1 |
| Anzola, JV; Beauregard, C; Chen, J; Coyle, AR; Gamache, DA; Govek, SP; Hellberg, MR; Hsien, JN; Lerch, JM; Liao, JC; Malecha, JW; Noble, SA; Oshiro, G; Shiau, AK; Staszewski, LM; Thomas, DJ; Yanni, JM | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Abdel-Wahab, BA; Albarqi, HA; Aljadaan, AM; Alqhtani, H; Hassanein, EHM; Khateeb, MM; Walbi, IA | 1 |
| Abou Saleh, L; Aragon, IV; Boyd, A; Koloteva, A; McDonough, W; Murphy, JM; Rich, J; Richter, W | 1 |
| Bednorz, M; Ghofrani, HA; Grimminger, F; Parajuli, N; Pichl, A; Schermuly, RT; Seeger, W; Seimetz, M; Weissmann, N | 1 |
| de Visser, YP; Laghmani, el H; Middeldorp, M; Steendijk, P; van der Laarse, A; Wagenaar, GT; Walther, FJ | 1 |
| Baik, KU; Cho, JY; Kim, HP; Lee, JG; Park, JS; Park, MH; Yoo, ES | 1 |
| Beume, R; Bundschuh, DS; Marx, D; Wohlsen, A; Wollin, L | 1 |
| de Visser, YP; Laghmani, EH; Nieuwland, K; van Wijngaarden, S; Wagenaar, GT; Walther, FJ | 1 |
| Gozzard, N; Higgs, G; Holbrook, M; Hughes, B; James, T | 1 |
| Alexander, R; Allen, R; Blease, K; Bloxham, D; Boyd, E; Catterall, C; Eaton, M; Gozzard, N; Head, J; Higgs, G; Holbrook, M; Howat, D; Hughes, B; Hughes, P; James, T; Kingaby, R; Lisle, H; Lumb, S; Merriman, M; Owens, R; Perry, M; Russell, A; Smith, B; Wales, M; Warrellow, G | 1 |
| Ehinger, AM; Ehinger, B; Gorr, G; Hoppmann, J; Kietzmann, M; Telser, E | 1 |
| Egging, EA; Gullikson, GW; Hammerbeck, DM; Hupperts, AM; Johnson, DD; McGurran, SM; Radziszewski, PL | 1 |
14 other study(ies) available for rp 73401 and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis and biological evaluation of imidazol-2-one and 2-cyanoiminoimidazole derivatives: novel series of PDE4 inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Dose-Response Relationship, Drug; Ear Diseases; Enzyme Inhibitors; Humans; Imidazoles; Inflammation; Inhibitory Concentration 50; Rats; Structure-Activity Relationship | 2002 |
Water-soluble PDE4 inhibitors for the treatment of dry eye.
Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents; Binding Sites; Computer Simulation; Coumarins; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Dry Eye Syndromes; Phosphodiesterase 4 Inhibitors; Rabbits; Rats; Water | 2010 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Piclamilast mitigates 1,2-dimethylhydrazine induced colon cancer in rats through modulation of Ras/PI3K/Akt/mTOR and NF-κβ signaling.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Apoptosis; Benzamides; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Male; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphodiesterase 4 Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; ras Proteins; Rats; Rats, Wistar; Signal Transduction; TOR Serine-Threonine Kinases | 2021 |
PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.
Topics: Aminopyridines; Animals; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Disease Models, Animal; Female; Gastroparesis; Mice; Mice, Nude; Phosphodiesterase 4 Inhibitors; Pyridines; Pyrimidinones; Rolipram | 2020 |
Cigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in Mice.
Topics: Animals; Benzamides; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Hypertension, Pulmonary; Lung; Lung Compliance; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Pyridines; Smoke; Smoking; Tadalafil | 2015 |
Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats.
Topics: Animals; Animals, Newborn; Benzamides; Bronchopulmonary Dysplasia; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Heart; Heart Injuries; Humans; Hyperoxia; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infant, Newborn; Lung; Oxidative Stress; Oxygen; Phosphodiesterase 4 Inhibitors; Pulmonary Alveoli; Pyridines; Rats | 2012 |
Differential effect of phosphodiesterase IV inhibitor RP73401 on various inflammatory and immune responses relevent to rheumatoid arthritis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arachidonic Acid; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Cell Physiological Phenomena; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Drug Evaluation, Preclinical; Ear Diseases; Edema; Humans; Immunity, Active; Inflammation; Lipopolysaccharides; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Spleen; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2004 |
Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Aminopyridines; Animals; Benzamides; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Carboxylic Acids; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Disease Models, Animal; Immunization; Male; Neutrophils; Nitriles; Ovalbumin; Phosphodiesterase Inhibitors; Pneumonia; Pyridines; Rats; Respiratory Hypersensitivity; Rolipram; Serotonin; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
Phosphodiesterase-4 inhibition attenuates pulmonary inflammation in neonatal lung injury.
Topics: Animals; Animals, Newborn; Benzamides; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Profiling; Humans; Infant, Newborn; Inflammation; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Alveoli; Pulmonary Fibrosis; Pyridines; Rats; Rats, Wistar; Respiration, Artificial; Respiratory Distress Syndrome; Rolipram | 2008 |
Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor.
Topics: Analysis of Variance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle Relaxation; Parasympathomimetics; Phosphodiesterase Inhibitors; Pyridines; Pyrrolidinones; Rolipram; Trachea; Vagus Nerve | 1996 |
The inhibition of antigen-induced eosinophilia and bronchoconstriction by CDP840, a novel stereo-selective inhibitor of phosphodiesterase type 4.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Analysis of Variance; Animals; Asthma; Benzamides; Bronchoconstriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Humans; Interleukin-5; Isoenzymes; Lung; Male; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridines; Pyrrolidinones; Rabbits; Rats; Rolipram | 1996 |
Effects of the phosphodiesterase 4 inhibitor RPR 73401 in a model of immunological inflammation.
Topics: Administration, Topical; Animals; Benzamides; Cyclosporine; Dermatitis, Allergic Contact; Dinitrobenzenes; Disease Models, Animal; Female; Interleukin-4; Mice; Mice, Inbred BALB C; Phosphodiesterase Inhibitors; Pyridines; Toluene 2,4-Diisocyanate | 2000 |
Effects of several glucocorticosteroids and PDE4 inhibitors on increases in total lung eosinophil peroxidase (EPO) levels following either systemic or intratracheal administration in sephadex- or ovalbumin-induced inflammatory models.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Androstadienes; Animals; Asthma; Beclomethasone; Benzamides; Budesonide; Cyclic Nucleotide Phosphodiesterases, Type 4; Dexamethasone; Dextrans; Disease Models, Animal; Enzyme Inhibitors; Eosinophil Peroxidase; Eosinophils; Fluticasone; Glucocorticoids; Guinea Pigs; Inflammation; Lung; Male; Ovalbumin; Peroxidases; Pyridines; Rats; Rats, Sprague-Dawley; Rolipram | 2000 |