Compounds > roxifiban
Page last updated: 2024-09-05

roxifiban and Thrombosis

roxifiban has been researched along with Thrombosis in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billheimer, JT; He, B; Seiffert, D; Spitz, SM; Stern, AM1
Kapil, R; Mousa, SA; Mu, DX1
Christ, DD; Diamond, S; Gan, L; Mutlib, AE; Nemeth, G; Shockcor, J; Way, R1
Abulencia, JP; Konstantopoulos, K; McCarty, OJ; Mousa, SA; Turner, NA1

Other Studies

5 other study(ies) available for roxifiban and Thrombosis

ArticleYear
Effects of glycoprotein IIb/IIIa antagonists on platelet activation: development of a transfer method to mimic peak to trough receptor occupancy.
    Thrombosis research, 2002, Sep-15, Volume: 107, Issue:6

    Topics: Alanine; Amidines; Benzodiazepines; Blood Platelets; Humans; In Vitro Techniques; Isoxazoles; Oximes; P-Selectin; Piperidines; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombosis

2002
Intravenous and oral antithrombotic efficacy of the novel platelet GPIIb/IIIa antagonist roxifiban (DMP754) and its free acid form, XV459.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:10

    Topics: Administration, Oral; Amidines; Amino Acids; Animals; Bleeding Time; Disease Models, Animal; Dogs; Electroshock; Female; Femoral Artery; Humans; Injections, Intravenous; Isoxazoles; Male; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis

1999
Roxifiban. DMP 754, MK 0853, XJ 754.
    Drugs in R&D, 1999, Volume: 1, Issue:5

    Topics: Amidines; Animals; Dogs; Humans; In Vitro Techniques; Isoxazoles; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis

1999
Mass spectrometric and NMR characterization of metabolites of roxifiban, a potent and selective antagonist of the platelet glycoprotein IIb/IIIa receptor.
    Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:11

    Topics: Amidines; Amino Acids; Animals; Cardiovascular Agents; Chromatography, High Pressure Liquid; Dogs; Feces; Gas Chromatography-Mass Spectrometry; Humans; Isoxazoles; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Thrombosis

2000
Comparative efficacy between the glycoprotein IIb/IIIa antagonists roxifiban and orbofiban in inhibiting platelet responses in flow models of thrombosis.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:4

    Topics: Alanine; Amidines; Blood Platelets; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; Isoxazoles; Models, Biological; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombosis

2002