Page last updated: 2024-08-17

rotenone and Nerve Degeneration

rotenone has been researched along with Nerve Degeneration in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (2.82)	18.2507
2000's	36 (50.70)	29.6817
2010's	27 (38.03)	24.3611
2020's	6 (8.45)	2.80

Authors

Authors	Studies
Gazzin, S; Jayanti, S; Moretti, R; Tiribelli, C	1
Chen, C; Hu, AL; Li, H; Liu, J; Zhang, BB; Zhang, F	1
Adeniyi, PA; Agedah, AE; Awogbindin, IO; Farombi, EO; Ogbuewu, E; Olorunkalu, PD; Oyetunde, BF	1
Buck, SA; De Miranda, BR; Fish, KN; Freyberg, Z; Greenamyre, JT; Logan, RW	1
Himori, N; Inoue-Yanagimachi, M; Nakazawa, T; Tawarayama, H	1
Guo, Q; Liu, Z; Smith, WW; Wang, B; Wang, X; Zhu, Y	1
Biswas, J; Gupta, P; Gupta, S; Singh, A; Singh, DK; Singh, S; Verma, DK	1
Capps, J; Virga, DM; Vohra, BPS	1
Almeida, MF; Cardoso, SM; Chaves, RS; Demasi, M; Ferrari, MFR; Marcourakis, T; Melo, KP; Netto, LES; Silva, CM	1
Hong, JS; Huang, C; Li, H; Liu, J; Song, S; Wang, Y; Zhang, F	1
Fang, Q; Homberg, JR; Li, W; Liao, P; Liu, C; Luan, Y; Meng, X; Shan, L; Shen, J; Swaab, DF; Wang, J; Zhou, P	1
Asanuma, M; Isooka, N; Kikuoka, R; Kitamura, Y; Miyazaki, I; Wada, K	1
Ansari, SA; Azimullah, S; Javed, H; Meeran, MFN; Ojha, S	1
Adem, A; Azimullah, S; Beiram, R; Jalal, FY; Jayaraj, RL; Meeran, MFN; Ojha, SK	1
Ali, SF; Beaudoin, MA; Binienda, ZK; Gough, B; Imam, SZ; Mohammed-Saeed, L; Paule, MG; Sarkar, S	1
Black, JA; Estacion, M; Kim, I; Persson, AK; Waxman, SG; Zhao, P	1
Ho, P; Tan, EK; Tio, M; Toh, J; Wang, HS; Zhao, Y	1
Bai, Q; Burton, EA; Cannon, JR; El Ayadi, A; Greenamyre, JT; Hastings, TG; Horowitz, MP; Shah, V; Tapias, V; Zharikov, AD	1
Abul Khair, SB; Azimullah, S; Haque, ME; Javed, H; Ojha, S	1
Hotta, K; Oka, K; Shindo, Y; Suzuki, K; Yamanaka, R	1
Anbalagan, C; Chikka, MR; Dombeck, K; Dvorak, K; Prahlad, V	1
Belenguer, P; Lassus, B; Magnifico, S; Miquel, MC; Peyrin, JM; Pignon, S	1
Yang, Q; Ye, Y; Zhao, C; Zhao, J	1
Jungling, A; Kiss, T; Maasz, G; Petrovics, D; Pirger, Z; Reglodi, D; Rivnyak, A; Tamas, A; Zrinyi, Z	1
Chen, S; Fan, X; Le, W; Li, L; Li, X; Ming, M; Peng, C; Yang, D	1
Hineno, A; Ikeda, S; Kaneko, K; Yoshida, K	1
Banik, NL; Butler, JT; Ray, SK; Samantaray, S	1
Cannon, JR; Drolet, RE; Greenamyre, JT; Honick, AS; Na, HM; Tapias, V	1
Gonzalez-Lima, F; Kane, JR; Kermath, BA; Rojas, JC; Schallert, T; Simola, N	1
Ariga, H; Inden, M; Kitamura, Y; Shibaike, T; Taira, T; Takata, K; Tamaki, A; Taniguchi, T; Yamamoto, A; Yanagida, T; Yasui, H	1
Liu, L; Wang, X; Wang, Y	1
Jackson, T; Jengelley, TA; Jnobaptiste, R; McNaught, KS	1
Corona, JC; Díaz-Nido, J; Gimenez-Cassina, A; Lim, F	1
Bayersdorfer, F; Botella, JA; Schneuwly, S; Voigt, A	1
Behl, C; Hajieva, P; Kern, A; Mocko, JB; Moosmann, B	1
Choi, WS; Palmiter, RD; Xia, Z	1
Mathur, R; Nath, C; Patro, IK; Sharma, S; Singh, S; Swarnkar, S	1
Cuenca, N; De Juan, E; Esteve-Rudd, J; Fernández-Sánchez, L; Lax, P; Martín-Nieto, J	1
Ariza, D; Barbiero, JK; Bortolanza, M; Da Cunha, C; Dombrowski, PA; Lima, MM; Moreira, CG; Sabioni, P; Vital, MA	1
Jantas, D; Konieczny, J; Kuśmierczyk, J; Lasoń, W; Lenda, T; Lorenc-Koci, E; Roman, A	1
Gao, HM; Hong, JS; Liu, B; Zhang, W	1
Breidert, T; Cohen-Salmon, C; Feger, J; Hirsch, EC; Höglinger, G; Launay, JM; Parain, K; Prigent, A; Rousselet, E; Ruberg, M	1
Ali, SF; Appel, SH; Dong, Z; He, Y; Imam, SZ; Jankovic, J; Le, W	1
Asanuma, M; Diaz-Corrales, FJ; Miyazaki, I; Ogawa, N	1
Antkiewicz-Michaluk, L; Bojarski, A; Michaluk, J; Romaska, I; Vetulani, J; Wardas, J	1
Uversky, VN	1
Hyland, K; Kang, UJ; Krencik, R; Kweon, GR; Leung, EH; Marks, JD; Schumacker, PT	1
Carvey, PM; Chang, QA; Leurgans, SE; Ling, Z; Lipton, JW; Tong, CW	1
Birman, S; Coulom, H	1
Greenamyre, JT; Sherer, TB; Testa, CM	1
Baier-Bitterlich, G; Böck, G; Heftberger, V; Podhraski, V; Tomaselli, B	1
Asanuma, M; Diaz-Corrales, FJ; Miyazaki, I; Miyoshi, K; Ogawa, N	1
Ahmadi, F; Fariss, MW; Grammatopoulos, TN; Jones, SM; Weyhenmeyer, JA; Zawada, WM	1
Kress, GJ; Reynolds, IJ	1
Feng, J; Jiang, H; Jiang, Q; Liu, W; Ren, Y	1
Bence, NF; Betarbet, R; Canet-Aviles, RM; Cookson, MR; Greenamyre, JT; Kim, JH; Klinefelter, G; Kopito, R; Lund, S; Mastroberardino, PG; McLendon, C; Na, HM; Seo, BB; Sherer, TB; Taylor, G; Yagi, A; Yagi, T	1
Mohanakumar, KP; Saravanan, KS; Senthilkumar, KS; Sindhu, KM	1
Mirzaei, H; Regnier, F; Rochet, JC; Schieler, JL	1
Kordower, JH; O'Malley, J; Soderstrom, K; Steece-Collier, K	1
Alam, M; Schmidt, WJ	1
Han, ES; Kim, YJ; Ko, HH; Lee, CS	1
Ding, JH; Hu, G; Sun, XL; Wu, JY; Yao, HH; Zhou, F	1
Banik, NL; Guyton, MK; Knaryan, VH; Matzelle, DD; Ray, SK; Samantaray, S	1
Cavada, C; Cuadrado, A; de Sagarra, MR; Rojo, AI	1
Barreto, G; Bertolino, LA; Capani, F; Giraldez, LD; Madureira de Oliveria, D; Saraceno, E; Valverde G De Andrade, D	1
Milbrandt, J; Press, C	1
Almeida, A; Bolaños, JP; Heales, SJ; Medina, JM	1
Duan, W; Mattson, MP	1
Betarbet, R; Garcia-Osuna, M; Greenamyre, JT; MacKenzie, G; Panov, AV; Sherer, TB	1
Bennett, JP; Borland, K; Parks, JK; Sherer, TB; Trimmer, PA; Tuttle, JB	1
Ross, GM; Shin, SH; Song, JH	1

Reviews

4 review(s) available for rotenone and Nerve Degeneration

Article	Year
Animal models of Parkinson's disease in rodents induced by toxins: an update. Journal of neural transmission. Supplementum, 2003, Issue:65 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Animals; Basal Ganglia; Brain Stem; Disease Models, Animal; Dopamine; Dopamine Agents; Nerve Degeneration; Neurons; Oxidopamine; Parkinson Disease; Rodentia; Rotenone; Uncoupling Agents	2003
Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell and tissue research, 2004, Volume: 318, Issue:1 Topics: Animals; Disease Models, Animal; Fungicides, Industrial; Herbicides; Maneb; Nerve Degeneration; Neurotoxins; Paraquat; Parkinson Disease; Rotenone; Uncoupling Agents	2004
Neural repair strategies for Parkinson's disease: insights from primate models. Cell transplantation, 2006, Volume: 15, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Transplantation; Deep Brain Stimulation; Disease Models, Animal; Fungicides, Industrial; Glial Cell Line-Derived Neurotrophic Factor; Herbicides; Humans; Maneb; Nerve Degeneration; Oxidopamine; Paraquat; Parkinson Disease; Pesticides; Primates; Rotenone	2006
Controversies on new animal models of Parkinson's disease pro and con: the rotenone model of Parkinson's disease (PD). Journal of neural transmission. Supplementum, 2006, Issue:70 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Dopamine Agents; Humans; Nerve Degeneration; Oxidopamine; Parkinson Disease, Secondary; Rotenone; Uncoupling Agents	2006

Other Studies

67 other study(ies) available for rotenone and Nerve Degeneration

Article	Year
Bilirubin Prevents the TH International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22 Topics: Bilirubin; Dopamine; Dopaminergic Neurons; Humans; Nerve Degeneration; Parkinson Disease; Rotenone; Tumor Necrosis Factor-alpha	2022
Protective role of cinnabar and realgar in Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity and disturbance of gut microbiota in rats. Journal of ethnopharmacology, 2020, Jan-30, Volume: 247 Topics: Animals; Arsenicals; Disease Models, Animal; DNA, Bacterial; Dopaminergic Neurons; Drugs, Chinese Herbal; Enterobacteriaceae; Ethnopharmacology; Gastrointestinal Microbiome; Humans; Inflammation Mediators; Lactobacillaceae; Lipopolysaccharides; Male; Mercury Compounds; Microglia; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; RNA, Ribosomal, 16S; Rotenone; Sulfides; Verrucomicrobia	2020
Kolaviron protects against nigrostriatal degeneration and gut oxidative damage in a stereotaxic rotenone model of Parkinson's disease. Psychopharmacology, 2020, Volume: 237, Issue:11 Topics: Animals; Corpus Striatum; Dopaminergic Neurons; Flavonoids; Gastrointestinal Microbiome; Male; Nerve Degeneration; Neuroprotective Agents; Parkinsonian Disorders; Plant Extracts; Rats; Rotenone; Stereotaxic Techniques; Substantia Nigra	2020
VGLUT2 Is a Determinant of Dopamine Neuron Resilience in a Rotenone Model of Dopamine Neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021, 06-02, Volume: 41, Issue:22 Topics: Animals; Dopaminergic Neurons; Insecticides; Male; Nerve Degeneration; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Rotenone; Vesicular Glutamate Transport Protein 2	2021
Glial cells modulate retinal cell survival in rotenone-induced neural degeneration. Scientific reports, 2021, 05-27, Volume: 11, Issue:1 Topics: Animals; Cell Survival; Culture Media, Conditioned; Cytokines; Ependymoglial Cells; Intercellular Signaling Peptides and Proteins; Microglia; Nerve Degeneration; Oxidative Stress; Rats; Retinal Ganglion Cells; Rotenone	2021
Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models. Cells, 2021, 07-21, Volume: 10, Issue:8 Topics: Adenine; Animals; Animals, Genetically Modified; Antioxidants; Antiparkinson Agents; Astrocytes; Autophagy; Behavior, Animal; Dihydroxyphenylalanine; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Male; Motor Activity; Nerve Degeneration; NF-E2-Related Factor 2; Oleanolic Acid; Parkinsonian Disorders; Phenotype; Rats, Sprague-Dawley; Repressor Proteins; Rotenone; Signal Transduction; Sirolimus	2021
Minocycline diminishes the rotenone induced neurotoxicity and glial activation via suppression of apoptosis, nitrite levels and oxidative stress. Neurotoxicology, 2018, Volume: 65 Topics: Animals; Apoptosis; Astrocytes; Brain; Caspase 3; CD11b Antigen; DNA Fragmentation; Glutathione; Lipid Peroxidation; Male; Microglia; Microtubule-Associated Proteins; Minocycline; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrites; Oxidative Stress; Rats; Rotenone; Stress, Physiological	2018
Enteric Neurodegeneration is Mediated Through Independent Neuritic and Somal Mechanisms in Rotenone and MPP+ Toxicity. Neurochemical research, 2018, Volume: 43, Issue:12 Topics: 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Enteric Nervous System; Female; Insecticides; Mice; MPTP Poisoning; Nerve Degeneration; Neurites; Parkinson Disease, Secondary; Parkinsonian Disorders; Pregnancy; Rotenone	2018
Mild Exercise Differently Affects Proteostasis and Oxidative Stress on Motor Areas During Neurodegeneration: A Comparative Study of Three Treadmill Running Protocols. Neurotoxicity research, 2019, Volume: 35, Issue:2 Topics: Animals; Exercise Test; Insecticides; Male; Motor Cortex; Nerve Degeneration; Oxidative Stress; Physical Conditioning, Animal; Proteostasis; Rats; Rats, Inbred Lew; Rotenone	2019
Low-Grade Inflammation Aggravates Rotenone Neurotoxicity and Disrupts Circadian Clock Gene Expression in Rats. Neurotoxicity research, 2019, Volume: 35, Issue:2 Topics: Animals; Circadian Clocks; Dopaminergic Neurons; Gene Expression; Inflammation; Inflammation Mediators; Insecticides; Lipopolysaccharides; Male; Nerve Degeneration; Period Circadian Proteins; Rats; Rats, Sprague-Dawley; Rotenone	2019
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model. Brain, behavior, and immunity, 2019, Volume: 76 Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Histamine; Indoles; Inflammation; Male; Microglia; Nerve Degeneration; Parkinson Disease; Parkinsonian Disorders; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H4; Rotenone	2019
Effects of Enteric Environmental Modification by Coffee Components on Neurodegeneration in Rotenone-Treated Mice. Cells, 2019, 03-07, Volume: 8, Issue:3 Topics: Animals; Astrocytes; Caffeic Acids; Chlorogenic Acid; Coffee; Dopaminergic Neurons; Down-Regulation; Enteric Nervous System; Intestines; Male; Mesencephalon; Metallothionein; Mice, Inbred C57BL; Myenteric Plexus; Neostriatum; Nerve Degeneration; Neuroglia; Neuroprotective Agents; Rats, Sprague-Dawley; Rotenone; Up-Regulation	2019
Neuroprotective Effects of Thymol, a Dietary Monoterpene Against Dopaminergic Neurodegeneration in Rotenone-Induced Rat Model of Parkinson's Disease. International journal of molecular sciences, 2019, Mar-27, Volume: 20, Issue:7 Topics: Animals; Catalase; Cyclooxygenase 2; Cytokines; Diet; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Inflammation Mediators; Lipid Peroxidation; Male; Malondialdehyde; Neostriatum; Nerve Degeneration; Neuroglia; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Rats, Wistar; Rotenone; Substantia Nigra; Superoxide Dismutase; Thymol; Tyrosine 3-Monooxygenase	2019
Lycopodium Attenuates Loss of Dopaminergic Neurons by Suppressing Oxidative Stress and Neuroinflammation in a Rat Model of Parkinson's Disease. Molecules (Basel, Switzerland), 2019, Jun-10, Volume: 24, Issue:11 Topics: alpha-Synuclein; Animals; Antioxidants; Brain; Catalase; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Inflammation; Inflammation Mediators; Lipid Peroxidation; Lycopodium; Male; Malondialdehyde; Matrix Metalloproteinases; Microglia; Nerve Degeneration; Neuroprotection; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Parkinson Disease; Plant Extracts; Rats, Wistar; Rotenone; Superoxide Dismutase	2019
Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage. Neuroscience letters, 2013, Apr-29, Volume: 541 Topics: Action Potentials; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Nerve Degeneration; Neural Conduction; Peripheral Nervous System Diseases; Pesticides; Rats; Rats, Sprague-Dawley; Rotenone; Sciatic Nerve; Tail	2013
Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Dec-04, Volume: 33, Issue:49 Topics: Animals; Axons; Axotomy; Cell Death; Cells, Cultured; Ganglia, Spinal; Humans; Hydrogen Peroxide; Immunohistochemistry; Mice; Mice, Transgenic; Microtubules; Mitochondrial Diseases; Nerve Degeneration; Neurites; Oxidants; Rotenone; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin; Thiourea; Uncoupling Agents	2013
In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila. Molecular brain, 2014, Oct-08, Volume: 7 Topics: Animals; Drosophila melanogaster; Drosophila Proteins; Humans; Motor Activity; Mutation; Nerve Degeneration; Neurons; Rotenone; Vesicular Transport Proteins	2014
shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model. The Journal of clinical investigation, 2015, Jul-01, Volume: 125, Issue:7 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Gene Knockdown Techniques; Male; Nerve Degeneration; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Rats, Transgenic; RNA, Messenger; RNA, Small Interfering; Rotenone; Substantia Nigra	2015
Neuroprotective potential of ferulic acid in the rotenone model of Parkinson's disease. Drug design, development and therapy, 2015, Volume: 9 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Brain; Calcium-Binding Proteins; Coumaric Acids; Cyclooxygenase 2; Cytokines; Cytoprotection; Disease Models, Animal; Dopaminergic Neurons; Glial Fibrillary Acidic Protein; Glutathione; Inflammation Mediators; Lipid Peroxidation; Male; Microfilament Proteins; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Reactive Oxygen Species; Rotenone; Time Factors	2015
Altered expression of Mg(2+) transport proteins during Parkinson's disease-like dopaminergic cell degeneration in PC12 cells. Biochimica et biophysica acta, 2016, Volume: 1863, Issue:8 Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cation Transport Proteins; Cell Differentiation; Hydrogen Peroxide; Ion Transport; Magnesium; Membrane Potential, Mitochondrial; Mitochondria; MPTP Poisoning; Nerve Degeneration; Nerve Growth Factor; PC12 Cells; Rats; RNA Interference; RNA, Messenger; RNA, Small Interfering; Rotenone	2016
The Mitochondria-Regulated Immune Pathway Activated in the C. elegans Intestine Is Neuroprotective. Cell reports, 2016, 08-30, Volume: 16, Issue:9 Topics: Activating Transcription Factors; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dopamine; Dopaminergic Neurons; Electron Transport Complex I; Epithelial Cells; Gastrointestinal Tract; Gene Expression Regulation; Immunity, Innate; Mitochondria; Mitophagy; Nerve Degeneration; p38 Mitogen-Activated Protein Kinases; Rotenone; Signal Transduction	2016
Alterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insults. Scientific reports, 2016, 09-08, Volume: 6 Topics: Animals; Apoptosis; Axons; Cells, Cultured; Dynamins; GTP Phosphohydrolases; Lab-On-A-Chip Devices; Mice; Mitochondrial Dynamics; Nerve Degeneration; Quinazolinones; Rotenone	2016
Synthesis and neuroprotective effects of the complex nanoparticles of iron and sapogenin isolated from the defatted seeds of Camellia oleifera. Pharmaceutical biology, 2017, Volume: 55, Issue:1 Topics: Acetylcholine; Animals; Behavior, Animal; Biomarkers; Biphenyl Compounds; Brain; Camellia; Chlorides; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Compounding; Ferric Compounds; Free Radical Scavengers; Injections, Intravenous; Injections, Subcutaneous; Male; Malondialdehyde; Metal Nanoparticles; Mice; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Picrates; Plants, Medicinal; Rotenone; Sapogenins; Seeds; Superoxide Dismutase; Tyrosine 3-Monooxygenase	2017
Pituitary adenylate cyclase-activating polypeptide (PACAP) has a neuroprotective function in dopamine-based neurodegeneration in rat and snail parkinsonian models. Disease models & mechanisms, 2017, 02-01, Volume: 10, Issue:2 Topics: Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Feeding Behavior; Locomotion; Mass Spectrometry; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Oxidopamine; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Deglycase DJ-1; Proteomics; Rats, Wistar; Rotenone; Serotonin; Snails; Substantia Nigra; Survival Analysis	2017
Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures. Journal of neuroscience research, 2008, Nov-15, Volume: 86, Issue:15 Topics: Animals; Astrocytes; Blotting, Western; Brain-Derived Neurotrophic Factor; Cells, Cultured; Culture Media, Conditioned; Dopamine; Enzyme-Linked Immunosorbent Assay; Genetic Therapy; Glial Cell Line-Derived Neurotrophic Factor; Homeodomain Proteins; Immunohistochemistry; In Vitro Techniques; Mesencephalon; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Transcription Factors; Transfection	2008
Increased vulnerability to rotenone-induced neurotoxicity in ceruloplasmin-deficient mice. Neuroscience letters, 2008, Nov-28, Volume: 446, Issue:1 Topics: Acrolein; Animals; Brain; Ceruloplasmin; Female; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Rotenone; Ubiquitin	2008
Extranigral neurodegeneration in Parkinson's disease. Annals of the New York Academy of Sciences, 2008, Volume: 1139 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Calpain; Cell Line; Dipeptides; Humans; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Parkinsonian Disorders; Rotenone; Spinal Cord; Substantia Nigra; Uncoupling Agents	2008
A highly reproducible rotenone model of Parkinson's disease. Neurobiology of disease, 2009, Volume: 34, Issue:2 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Hypokinesia; Injections, Intraperitoneal; Male; Muscle Rigidity; Nerve Degeneration; Neurons; Neurotoxins; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Reproducibility of Results; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase; Ubiquitins; Uncoupling Agents	2009
Striatal neuroprotection with methylene blue. Neuroscience, 2009, Oct-20, Volume: 163, Issue:3 Topics: Animals; Antioxidants; Behavior, Animal; Corpus Striatum; Electron Transport Complex I; Electron Transport Complex IV; Male; Methylene Blue; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rotenone	2009
Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice. Neurochemistry international, 2009, Volume: 55, Issue:8 Topics: alpha-Synuclein; Animals; Antiparkinson Agents; Apoptosis; Benzothiazoles; Cell Line, Tumor; Corpus Striatum; Cytochromes c; Dopamine; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Hydroxyl Radical; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neural Pathways; Neurotoxins; Oxidative Stress; Parkinsonian Disorders; Pramipexole; Proto-Oncogene Proteins c-bcl-2; Rotenone; Substantia Nigra; Uncoupling Agents	2009
HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. Neuroscience letters, 2009, Dec-31, Volume: 467, Issue:3 Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Apoptosis; Cell Line; Cell Survival; Dopamine; Drug Evaluation, Preclinical; Genetic Predisposition to Disease; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Mice; Nerve Degeneration; Neurons; Parkinson Disease; Rats; Rotenone; Substantia Nigra	2009
The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease. Synapse (New York, N.Y.), 2010, Volume: 64, Issue:3 Topics: Acetylcysteine; Animals; Blotting, Western; Canavanine; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Dopamine; Immunohistochemistry; Locus Coeruleus; Male; Nerve Degeneration; Neurons; Oxidative Stress; Parkinson Disease; Proteasome Endopeptidase Complex; Protein Folding; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Ubiquitin-Activating Enzymes; Ubiquitin-Conjugating Enzymes; Uncoupling Agents	2010
Hexokinase II gene transfer protects against neurodegeneration in the rotenone and MPTP mouse models of Parkinson's disease. Journal of neuroscience research, 2010, Volume: 88, Issue:9 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Catalepsy; Cell Death; Dopamine; Genetic Therapy; Genetic Vectors; Herpesvirus 1, Human; Hexokinase; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Parkinsonian Disorders; Rotenone; Substantia Nigra; Treatment Outcome	2010
Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease. Neurobiology of disease, 2010, Volume: 40, Issue:1 Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Dopamine; Drosophila melanogaster; Humans; Models, Genetic; Nerve Degeneration; Parkinson Disease; Rotenone	2010
Phenothiazines interfere with dopaminergic neurodegeneration in Caenorhabditis elegans models of Parkinson's disease. Neurobiology of disease, 2010, Volume: 40, Issue:1 Topics: Animals; Animals, Genetically Modified; Antipsychotic Agents; Caenorhabditis elegans; Disease Models, Animal; Dopamine; Humans; Insecticides; Models, Genetic; Nerve Degeneration; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Phenothiazines; Rotenone	2010
Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. The Journal of cell biology, 2011, Mar-07, Volume: 192, Issue:5 Topics: 1-Methyl-4-phenylpyridinium; Animals; Cytoplasm; Disease Models, Animal; Dopamine; Electron Transport Complex I; Mice; Microtubules; NAD; Nerve Degeneration; Parkinson Disease; Reactive Oxygen Species; Rotenone; Substantia Nigra; Vesicular Monoamine Transport Proteins	2011
Rotenone induced neurotoxicity in rat brain areas: a histopathological study. Neuroscience letters, 2011, Sep-01, Volume: 501, Issue:3 Topics: Animals; Brain; Corpus Striatum; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Insecticides; Male; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2011
Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina. Neurobiology of disease, 2011, Volume: 44, Issue:1 Topics: Amacrine Cells; Animals; Blotting, Western; Body Weight; Dopaminergic Neurons; Electroretinography; Immunohistochemistry; Mitochondria; Nerve Degeneration; Neurotoxicity Syndromes; Photoreceptor Cells; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Synapses; Uncoupling Agents	2011
Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin. Neurotoxicity research, 2012, Volume: 21, Issue:3 Topics: Animals; Avoidance Learning; Disease Models, Animal; Dopaminergic Neurons; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Microinjections; Motor Activity; Nerve Degeneration; Parkinsonian Disorders; Rats; Rats, Wistar; Rotenone; Serotonergic Neurons; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase; Uncoupling Agents	2012
The extent of neurodegeneration and neuroprotection in two chemical in vitro models related to Parkinson's disease is critically dependent on cell culture conditions. Neurotoxicity research, 2013, Volume: 24, Issue:1 Topics: Acetylcysteine; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Humans; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Rotenone; Time Factors; Tretinoin; Triterpenes	2013
Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Feb-15, Volume: 23, Issue:4 Topics: Animals; Cells, Cultured; Dopamine; Drug Synergism; Inflammation Mediators; Insecticides; Lipopolysaccharides; Membrane Glycoproteins; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; NADPH Oxidase 2; NADPH Oxidases; Nerve Degeneration; Neurons; Parkinson Disease; Rats; Rats, Inbred F344; Rotenone; Superoxides	2003
Role of nitric oxide in rotenone-induced nigro-striatal injury. Journal of neurochemistry, 2003, Volume: 86, Issue:6 Topics: Animals; Brain Chemistry; Cell Count; Cerebral Cortex; Corpus Striatum; Dopamine; Drug Administration Schedule; Enzyme Inhibitors; Female; Indazoles; Insecticides; NADPH Dehydrogenase; Nerve Degeneration; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction; Substantia Nigra; Time; Tyrosine 3-Monooxygenase; Uncoupling Agents	2003
Rotenone induces disassembly of the Golgi apparatus in the rat dopaminergic neuroblastoma B65 cell line. Neuroscience letters, 2004, Jan-02, Volume: 354, Issue:1 Topics: Animals; Apoptosis; Cell Line, Tumor; Dopamine; Endoplasmic Reticulum; Golgi Apparatus; Nerve Degeneration; Neuroblastoma; Neurons; Rats; Rotenone; Uncoupling Agents	2004
Protective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline against dopaminergic neurodegeneration in the extrapyramidal structures produced by intracerebral injection of rotenone. The international journal of neuropsychopharmacology, 2004, Volume: 7, Issue:2 Topics: Animals; Basal Ganglia Diseases; Brain Chemistry; Dopamine; Injections; Injections, Subcutaneous; Male; Medial Forebrain Bundle; Neostriatum; Nerve Degeneration; Neuroprotective Agents; Presynaptic Terminals; Rats; Rats, Wistar; Rotenone; Serotonin; Stereotaxic Techniques; Substantia Nigra; Tetrahydroisoquinolines; Uncoupling Agents	2004
Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells. The Journal of biological chemistry, 2004, Dec-10, Volume: 279, Issue:50 Topics: Animals; Antioxidants; Cell Differentiation; Cell Line; Dopamine; Electron Transport Complex I; Glycolysis; Mice; Models, Neurological; Nerve Degeneration; Neurons; Oxidative Phosphorylation; Oxidative Stress; Rotenone	2004
Rotenone potentiates dopamine neuron loss in animals exposed to lipopolysaccharide prenatally. Experimental neurology, 2004, Volume: 190, Issue:2 Topics: alpha-Synuclein; Animals; Brain; Dopamine; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Insecticides; Lewy Bodies; Lipopolysaccharides; Microglia; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Rotenone; Synucleins; Tyrosine 3-Monooxygenase	2004
Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Dec-01, Volume: 24, Issue:48 Topics: Animals; Antioxidants; Apoptosis; Brain; Cell Count; Dopamine; Dopamine Agonists; Drosophila melanogaster; Electron Transport Complex I; Insecticides; Levodopa; Locomotion; Melatonin; Nerve Degeneration; Neurons; Oxidative Stress; Parkinsonian Disorders; Phenotype; Rotenone	2004
Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures. Brain research. Molecular brain research, 2005, Mar-24, Volume: 134, Issue:1 Topics: alpha-Tocopherol; Animals; Animals, Newborn; Antioxidants; Blotting, Western; Cell Count; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Immunohistochemistry; Nerve Degeneration; Neurons; Organ Culture Techniques; Oxidative Stress; Rats; Rotenone; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase	2005
Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation. Neurochemistry international, 2005, Volume: 46, Issue:7 Topics: Adenosine; Animals; Cell Hypoxia; Cell Survival; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Guanosine; Hypoxia, Brain; Inosine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Degeneration; Nerve Growth Factor; Neuroprotective Agents; PC12 Cells; Purine Nucleosides; Rats; Rotenone; Uncoupling Agents	2005
Rotenone induces aggregation of gamma-tubulin protein and subsequent disorganization of the centrosome: relevance to formation of inclusion bodies and neurodegeneration. Neuroscience, 2005, Volume: 133, Issue:1 Topics: alpha-Synuclein; Animals; Astrocytes; Blotting, Western; Cell Death; Cells, Cultured; Centrosome; Dopamine; Female; Golgi Apparatus; Hypokinesia; Immunohistochemistry; Inclusion Bodies; Male; Mesencephalon; Nerve Degeneration; Nerve Tissue Proteins; Neurites; Pregnancy; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rotenone; Spindle Apparatus; Synucleins; Tubulin; Tyrosine 3-Monooxygenase; Uncoupling Agents	2005
Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death. Brain research, 2005, May-31, Volume: 1045, Issue:1-2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cell Death; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Insecticides; Losartan; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2005
Dopaminergic neurotoxins require excitotoxic stimulation in organotypic cultures. Neurobiology of disease, 2005, Volume: 20, Issue:3 Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Brain; Cell Death; Cell Nucleus; Cerebral Cortex; Corpus Striatum; Dopamine; Drug Synergism; Glutamic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2005
Selective vulnerability of dopaminergic neurons to microtubule depolymerization. The Journal of biological chemistry, 2005, Oct-07, Volume: 280, Issue:40 Topics: Cell Death; Colchicine; Cytosol; Dopamine; Humans; Microtubules; Nerve Degeneration; Nocodazole; Oxidative Stress; Paclitaxel; Parkinson Disease; Polymers; Receptors, Dopamine; Rotenone; Substantia Nigra; Uncoupling Agents	2005
Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiology of disease, 2006, Volume: 22, Issue:2 Topics: alpha-Synuclein; Animals; Cell Line, Tumor; Disease Models, Animal; Electron Transport Complex I; Energy Metabolism; Humans; Insecticides; Male; Mitochondria; Nerve Degeneration; Neurons; Oncogene Proteins; Oxidative Stress; Parkinsonian Disorders; Peroxiredoxins; Proteasome Endopeptidase Complex; Protein Deglycase DJ-1; Rats; Rats, Inbred Lew; Rotenone; Signal Transduction; Substantia Nigra; Ubiquitin	2006
L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats. Neurochemistry international, 2006, Volume: 49, Issue:1 Topics: Amphetamine; Animals; Catalase; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electron Transport Complex I; Hydroxyl Radical; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Selegiline; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase; Uncoupling Agents; Up-Regulation	2006
Identification of rotenone-induced modifications in alpha-synuclein using affinity pull-down and tandem mass spectrometry. Analytical chemistry, 2006, Apr-01, Volume: 78, Issue:7 Topics: alpha-Synuclein; Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Mitochondria; Molecular Sequence Data; Nerve Degeneration; Nervous System Diseases; Neurons; Oxidative Stress; Parkinson Disease; PC12 Cells; Protein Processing, Post-Translational; Rats; Rotenone; Tandem Mass Spectrometry	2006
Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death. Brain research bulletin, 2007, Mar-30, Volume: 71, Issue:6 Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Caspase 3; Cell Death; Cell Membrane Permeability; Cytochromes c; Electron Transport Complex I; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutathione; Lamotrigine; Membrane Potential, Mitochondrial; Mitochondria; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Rotenone; Triazines	2007
Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:12 Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Freezing Reaction, Cataleptic; Male; Membrane Potential, Mitochondrial; Microglia; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Propylamines; Rats; Rats, Sprague-Dawley; Rotenone; Tumor Necrosis Factor-alpha	2007
The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. Neuroscience, 2007, May-11, Volume: 146, Issue:2 Topics: Animals; Calpain; Caspase 3; CD11b Antigen; Choline O-Acetyltransferase; Enzyme Activation; Glial Fibrillary Acidic Protein; In Situ Nick-End Labeling; Male; Motor Neurons; Myelin Basic Protein; Nerve Degeneration; Phosphopyruvate Hydratase; Rats; Rats, Inbred Lew; Rotenone; Spinal Cord Diseases; Time Factors; Tyrosine 3-Monooxygenase	2007
Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats. Experimental neurology, 2007, Volume: 208, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Inhalation; Administration, Intranasal; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Herbicides; Insecticides; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neurons; Paraquat; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2007
Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells. Brain research, 2008, Mar-10, Volume: 1198 Topics: Apoptosis; Cell Line, Tumor; Cell Shape; Cell Survival; Cytoprotection; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Microscopy, Electron, Transmission; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Plant Extracts; Rotenone; Tetrazolium Salts; Thiazoles	2008
Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, May-07, Volume: 28, Issue:19 Topics: Adenosine Triphosphate; Animals; Antioxidants; Axons; Cells, Cultured; Down-Regulation; Ganglia, Spinal; Gene Transfer Techniques; Isoenzymes; Mitochondrial Diseases; Nerve Degeneration; Neurons; Nicotinamide-Nucleotide Adenylyltransferase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rotenone; Stress, Physiological; Vincristine	2008
Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion. Brain research, 1998, Apr-20, Volume: 790, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Antimycin A; Cell Respiration; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Glutathione; Mitochondria; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Radiation-Protective Agents; Rats; Rats, Wistar; Rotenone; Succinic Acid; Uncoupling Agents	1998
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. Journal of neuroscience research, 1999, Jul-15, Volume: 57, Issue:2 Topics: Animals; Antimetabolites; Apoptosis; Behavior, Animal; Carrier Proteins; Corpus Striatum; Deoxyglucose; Disease Models, Animal; Dopamine; Dopamine Agents; Endoplasmic Reticulum Chaperone BiP; Energy Intake; Ferrous Compounds; Heat-Shock Proteins; Heat-Shock Response; HSP70 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL; Mitochondria; Molecular Chaperones; MPTP Poisoning; Nerve Degeneration; Neurons; Parkinson Disease, Secondary; Reactive Oxygen Species; Rotenone; Substantia Nigra; Uncoupling Agents	1999
Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nature neuroscience, 2000, Volume: 3, Issue:12 Topics: Animals; Dopamine; Dyskinesias; Electron Transport Complex I; Environmental Exposure; Lewy Bodies; Male; NADH, NADPH Oxidoreductases; Neostriatum; Nerve Degeneration; Neural Pathways; Neurons; Parkinson Disease; Parkinson Disease, Secondary; Presynaptic Terminals; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2000
Chronic reduction in complex I function alters calcium signaling in SH-SY5Y neuroblastoma cells. Brain research, 2001, Feb-09, Volume: 891, Issue:1-2 Topics: Animals; Calcium Signaling; Cell Death; Electron Transport Complex I; Humans; Mitochondria; Models, Biological; NADH, NADPH Oxidoreductases; Nerve Degeneration; Neuroblastoma; Parkinson Disease; Reactive Oxygen Species; Rotenone; Tumor Cells, Cultured; Uncoupling Agents	2001
Oxidative stress induced by ascorbate causes neuronal damage in an in vitro system. Brain research, 2001, Mar-23, Volume: 895, Issue:1-2 Topics: Androstadienes; Animals; Apoptosis; Ascorbic Acid; Brain; Ceramides; Dehydroascorbic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Hypoxia-Ischemia, Brain; Lipid Peroxides; Male; Monosaccharide Transport Proteins; Nerve Degeneration; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction; Sphingomyelins; Stroke; Uncoupling Agents; Wortmannin	2001