Page last updated: 2024-08-17

rotenone and Necrosis

rotenone has been researched along with Necrosis in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (21.43)18.2507
2000's9 (32.14)29.6817
2010's10 (35.71)24.3611
2020's3 (10.71)2.80

Authors

AuthorsStudies
Entezari, M; Hashemi, M; Hojati, V; Khosravi, F; Mirzaei, S1
Cui, G; Hu, M; Li, Y; Sun, R; Sun, Z; Xue, L; Zhong, G1
Bosnjak, M; Harhaji-Trajkovic, L; Kosic, M; Kravic-Stevovic, T; Mircic, A; Paunovic, V; Ristic, B; Stevanovic, D; Trajkovic, V1
Callizot, N; Combes, M; Henriques, A; Poindron, P1
Ding, X; Hong, Y; Nie, H; Wei, X; Wu, D; Ying, W1
Ambudkar, SV; Liu, H; Mayer, M; Rao, DK1
Bird, MJ; Frazier, AE; Komen, JC; Laskowski, A; Ryan, MT; Thorburn, DR; Wijeyeratne, XW1
Casanelles, E; Garcia-Belinchón, M; Granados-Colomina, C; Iglesias-Guimarais, V; Martínez-Escardó, L; Pascual-Guiral, S; Ribas, J; Sánchez-Osuna, M; Yuste, VJ1
Gill, MB; Perez-Polo, JR1
Bravo, L; Cámara, C; Campuzano, S; Cuello, S; Goya, L; Madrid, Y; Pedrero, M; Ramos, S1
Herman, B; Lopez-Cruzan, M; Morgan, WW; Tiwari, M1
Adams, DH; Afford, SC; Bhatt, AN; Bhogal, RH; Curbishley, SM; Weston, CJ1
Patel, F1
Kabiraj, P; Miranda, M; Narayan, M; Pal, R; Varela-Ramirez, A1
Cantoni, O; Guidarelli, A; Sestili, P; Tommasini, I1
Allain, N; Fardel, O; Lagadic-Gossmann, D; Lemarié, A; Morzadec, C; Vernhet, L1
Cooper, JM; Gu, M; Iravani, MM; Irvani, M; Jenner, P; King, D; Schapira, AH1
Gille, G; Radad, K; Rausch, WD1
An, LJ; Bao, YM; Jiang, B; Liu, YM1
Gabai, VL; Kabakov, AE1
Cooper, JM; Hartley, A; Heron, C; Schapira, AH; Stone, JM1
Bour, ES; Cornman, GA; Isom, HC; Ward, LK1
Eguchi, Y; Kamiike, W; Matsuda, H; Shimizu, S; Tsujimoto, Y; Uchiyama, Y; Waguri, S1
Brambilla, L; Cantoni, O; Sestili, P1
Catisti, R; Vercesi, AE1
Leist, M; Nicotera, P; Single, B1
Almeida, A; Bolaños, JP1
Fariss, MW; Nicholls-Grzemski, FA; Tirmenstein, MA; Zhang, JG1

Other Studies

28 other study(ies) available for rotenone and Necrosis

ArticleYear
Curcumin neuroprotective effects in Parkinson disease during pregnancy.
    Brain research bulletin, 2023, Volume: 201

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Curcumin; Female; Mice; MicroRNAs; Necrosis; Neuroprotective Agents; Parkinson Disease; Pregnancy; Proto-Oncogene Proteins c-bcl-2; RNA, Circular; Rotenone

2023
Rotenone-induced necrosis in insect cells via the cytoplasmic membrane damage and mitochondrial dysfunction.
    Pesticide biochemistry and physiology, 2021, Volume: 173

    Topics: Animals; Apoptosis; Cell Membrane; Membrane Potential, Mitochondrial; Mitochondria; Necrosis; Rotenone

2021
3-Methyladenine prevents energy stress-induced necrotic death of melanoma cells through autophagy-independent mechanisms.
    Journal of pharmacological sciences, 2021, Volume: 147, Issue:1

    Topics: Adenine; AMP-Activated Protein Kinases; Animals; Autophagy; Cell Death; Deoxyglucose; JNK Mitogen-Activated Protein Kinases; Mechanistic Target of Rapamycin Complex 1; Melanoma; Melanoma, Experimental; Mice, Inbred C57BL; Mitochondria; Mitochondrial Swelling; Necrosis; Oxidative Stress; Phosphatidylinositol 3-Kinases; Rotenone

2021
Necrosis, apoptosis, necroptosis, three modes of action of dopaminergic neuron neurotoxins.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Apoptosis; Cells, Cultured; Dopaminergic Neurons; Embryo, Mammalian; Energy Metabolism; Female; Humans; Mesencephalon; Mitochondria; Necroptosis; Necrosis; Neurotoxins; Oxidative Stress; Oxidopamine; Parkinson Disease; Primary Cell Culture; Protein Aggregation, Pathological; Rats; Rotenone

2019
NAD(+) treatment prevents rotenone-induced apoptosis and necrosis of differentiated PC12 cells.
    Neuroscience letters, 2014, Feb-07, Volume: 560

    Topics: Animals; Apoptosis; Cell Differentiation; Insecticides; Membrane Potential, Mitochondrial; NAD; Necrosis; PC12 Cells; Rats; Rotenone

2014
A combination of curcumin with either gramicidin or ouabain selectively kills cells that express the multidrug resistance-linked ABCG2 transporter.
    The Journal of biological chemistry, 2014, Nov-07, Volume: 289, Issue:45

    Topics: Adenosine Triphosphate; Antimycin A; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caspase 3; Caspase 7; Curcumin; Drug Combinations; Drug Resistance, Multiple; Flow Cytometry; Gramicidin; HEK293 Cells; Humans; Hydrolysis; MCF-7 Cells; Membrane Potentials; Necrosis; Neoplasm Proteins; Ouabain; Patch-Clamp Techniques; Rotenone

2014
Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse.
    Bioscience reports, 2014, Nov-21, Volume: 34, Issue:6

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Blotting, Western; Cells, Cultured; Electron Transport Complex I; Electron Transport Complex II; Embryo, Mammalian; Fibroblasts; Galactose; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mice, Knockout; Mitochondria; Necrosis; Neurons; Reactive Oxygen Species; Rotenone; Succinates; Superoxides

2014
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
    The Journal of biological chemistry, 2015, Aug-21, Volume: 290, Issue:34

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carrier Proteins; Caspases; Cell Line, Tumor; Chromatin; Colchicine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Microfilament Proteins; Necrosis; Neurons; Nocodazole; Peptidomimetics; Quinolines; Rotenone; Signal Transduction; Staurosporine; Thapsigargin

2015
Bax shuttling after rotenone treatment of neuronal primary cultures: effects on cell death phenotypes.
    Journal of neuroscience research, 2009, Volume: 87, Issue:9

    Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Hypoxia-Ischemia, Brain; Microfilament Proteins; Necrosis; Neurons; Neuroprotective Agents; Organelles; Phenotype; Protein Transport; Rats; Rats, Wistar; Rotenone; Signal Transduction; Uncoupling Agents

2009
Molecular mechanisms of methylmercury-induced cell death in human HepG2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:5

    Topics: Antioxidants; Apoptosis; Caspase 3; Cell Survival; Environmental Pollutants; Enzyme Activation; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Methylmercury Compounds; Necrosis; Oxidative Stress; Oxidoreductases; Rotenone; Time Factors; Uncoupling Agents

2010
Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons.
    The Journal of biological chemistry, 2011, Mar-11, Volume: 286, Issue:10

    Topics: Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 2; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytochromes c; Gene Knockdown Techniques; Mice; Mice, Knockout; Mitochondria; Necrosis; Neurons; Oxidative Stress; Rotenone; Uncoupling Agents

2011
Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H-R).
    FEBS letters, 2011, Mar-23, Volume: 585, Issue:6

    Topics: Apoptosis; Cell Hypoxia; Cell Size; Cells, Cultured; Flow Cytometry; Hepatocytes; Humans; Mitochondria; Necrosis; Oxygen; Reactive Oxygen Species; Rotenone; Uncoupling Agents

2011
Pesticidal suicide: adult fatal rotenone poisoning.
    Journal of forensic and legal medicine, 2011, Volume: 18, Issue:7

    Topics: Chromatography, High Pressure Liquid; Female; Forensic Pathology; Forensic Toxicology; Humans; India; Insecticides; Liver; Lung; Middle Aged; Multiple Organ Failure; Necrosis; Pulmonary Edema; Rotenone; Suicide; Tandem Mass Spectrometry

2011
Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-β-hydroxybutyrate intervention.
    Biochemical and biophysical research communications, 2012, Sep-28, Volume: 426, Issue:3

    Topics: 3-Hydroxybutyric Acid; Apoptosis; Carrier Proteins; Caspases; Cell Line, Tumor; Dopaminergic Neurons; Green Fluorescent Proteins; Humans; Mitochondrial Diseases; Necrosis; Nerve Tissue Proteins; Neuroprotective Agents; Nitrates; Nitrosation; Oxidative Stress; Parkinson Disease; Protein Folding; Rotenone

2012
Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2.
    Cell death and differentiation, 2004, Volume: 11, Issue:9

    Topics: Antimycin A; Arachidonic Acid; Blotting, Western; Catalase; Cell Death; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Immunohistochemistry; Microscopy, Confocal; Mitochondria; Necrosis; Oligonucleotides; Oligonucleotides, Antisense; Oxygen Consumption; Peroxynitrous Acid; Phospholipases A; Phospholipases A2; Rotenone; Signal Transduction; Temperature; Transfection; U937 Cells

2004
Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor.
    Free radical biology & medicine, 2004, Jun-15, Volume: 36, Issue:12

    Topics: Active Transport, Cell Nucleus; Apoptosis; bcl-X Protein; Blotting, Northern; Blotting, Western; Cadmium; Calcium; Caspases; Cell Line; Chelating Agents; Cytoplasm; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Endodeoxyribonucleases; Humans; Liver; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Necrosis; NF-kappa B; Onium Compounds; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA; Rotenone; Ruthenium Red; Time Factors; Uncoupling Agents

2004
Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.
    Journal of neurochemistry, 2004, Volume: 91, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Antioxidants; Benzothiazoles; Carbocyanines; Caspase 3; Caspases; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; Humans; Jurkat Cells; L-Lactate Dehydrogenase; Mitochondria; Necrosis; Neuroblastoma; Pramipexole; Rotenone; Thiazoles

2004
Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration.
    Neurochemistry international, 2006, Volume: 49, Issue:4

    Topics: Animals; Apoptosis; Benzimidazoles; Cell Death; Cell Survival; Cells, Cultured; Culture Media; Dopamine; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; Immunohistochemistry; L-Lactate Dehydrogenase; Lactic Acid; Membrane Potentials; Mesencephalon; Mice; Mitochondria; Necrosis; Neurons; Oxygen Consumption; Pregnancy; Reactive Oxygen Species; Rotenone; Superoxides; Tyrosine 3-Monooxygenase; Uncoupling Agents

2006
Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Nucleus; Cell Survival; Dopamine; Flow Cytometry; Genes, bcl-2; Glutathione; Hydroxybenzoates; Membrane Potentials; Mitochondria; Necrosis; Neurotoxicity Syndromes; PC12 Cells; Rats; Reactive Oxygen Species; Rotenone; Uncoupling Agents

2008
Heat shock-induced accumulation of 70-kDa stress protein (HSP70) can protect ATP-depleted tumor cells from necrosis.
    Experimental cell research, 1995, Volume: 217, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cycloheximide; Hot Temperature; HSP70 Heat-Shock Proteins; Ischemia; Mice; Necrosis; Protein Synthesis Inhibitors; Rotenone; Tumor Cells, Cultured

1995
Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease.
    Journal of neurochemistry, 1994, Volume: 63, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Dose-Response Relationship, Drug; Electron Transport Complex I; NADH, NADPH Oxidoreductases; Necrosis; Parkinson Disease; PC12 Cells; Rats; Rotenone; Substantia Nigra

1994
Tumor necrosis factor-alpha-induced apoptosis in hepatocytes in long-term culture.
    The American journal of pathology, 1996, Volume: 148, Issue:2

    Topics: Animals; Apoptosis; Cell Culture Techniques; Culture Media; Dimethyl Sulfoxide; DNA; Electrophoresis, Agar Gel; Liver; Male; Necrosis; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Rotenone; Tumor Necrosis Factor-alpha

1996
Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions.
    Oncogene, 1996, May-16, Volume: 12, Issue:10

    Topics: Amino Acid Sequence; Animals; Antimycin A; Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Caspase 1; Cell Death; Cell Hypoxia; Cysteine Endopeptidases; DNA, Complementary; Humans; Molecular Sequence Data; Necrosis; PC12 Cells; Potassium Cyanide; Protease Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rotenone; Signal Transduction; Transfection; Tumor Cells, Cultured

1996
Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate.
    FEBS letters, 1999, Aug-20, Volume: 457, Issue:1

    Topics: Apoptosis; Cell Count; Cell Division; Cell Survival; Cyclosporine; DNA Fragmentation; Enzyme Inhibitors; Humans; Kinetics; Necrosis; Pyruvic Acid; Rotenone; tert-Butylhydroperoxide; Time Factors; U937 Cells; Uncoupling Agents

1999
The participation of pyridine nucleotides redox state and reactive oxygen in the fatty acid-induced permeability transition in rat liver mitochondria.
    FEBS letters, 1999, Dec-24, Volume: 464, Issue:1-2

    Topics: Animals; Apoptosis; Arachidonic Acid; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Electrophysiology; Fatty Acids; Female; Membrane Potentials; Mitochondria, Liver; NADP; Necrosis; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Wistar; Reactive Oxygen Species; Rotenone; Uncoupling Agents

1999
Differential effects of bcl-2 on cell death triggered under ATP-depleting conditions.
    Experimental cell research, 2001, Jan-01, Volume: 262, Issue:1

    Topics: Adenosine Triphosphate; Apoptosis; Cytochrome c Group; Glutathione; Humans; Intracellular Membranes; Jurkat Cells; Mitochondria; Necrosis; Nitric Oxide; Nitroso Compounds; Proto-Oncogene Proteins c-bcl-2; Rotenone; S-Nitrosoglutathione; Staurosporine; Time Factors

2001
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Cyclosporine; Electron Transport; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Membrane Potentials; Mitochondria; Models, Biological; NAD; NADH, NADPH Oxidoreductases; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligomycins; omega-N-Methylarginine; Permeability; Rats; Rats, Wistar; Receptors, Glutamate; Rotenone; Single-Blind Method; Succinate Cytochrome c Oxidoreductase

2001
Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents.
    Chemico-biological interactions, 2001, Dec-21, Volume: 138, Issue:3

    Topics: Animals; Antimycin A; Antioxidants; Cell Survival; Cells, Cultured; Drug Antagonism; Electron Transport; Enzyme Inhibitors; Ethyl Methanesulfonate; Hepatocytes; Lipid Peroxidation; Male; Mitochondria; Necrosis; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rotenone; Thenoyltrifluoroacetone; Tocopherols; Vitamin E

2001