rotenone has been researched along with Necrosis in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 10 (35.71) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Entezari, M; Hashemi, M; Hojati, V; Khosravi, F; Mirzaei, S | 1 |
| Cui, G; Hu, M; Li, Y; Sun, R; Sun, Z; Xue, L; Zhong, G | 1 |
| Bosnjak, M; Harhaji-Trajkovic, L; Kosic, M; Kravic-Stevovic, T; Mircic, A; Paunovic, V; Ristic, B; Stevanovic, D; Trajkovic, V | 1 |
| Callizot, N; Combes, M; Henriques, A; Poindron, P | 1 |
| Ding, X; Hong, Y; Nie, H; Wei, X; Wu, D; Ying, W | 1 |
| Ambudkar, SV; Liu, H; Mayer, M; Rao, DK | 1 |
| Bird, MJ; Frazier, AE; Komen, JC; Laskowski, A; Ryan, MT; Thorburn, DR; Wijeyeratne, XW | 1 |
| Casanelles, E; Garcia-Belinchón, M; Granados-Colomina, C; Iglesias-Guimarais, V; Martínez-Escardó, L; Pascual-Guiral, S; Ribas, J; Sánchez-Osuna, M; Yuste, VJ | 1 |
| Gill, MB; Perez-Polo, JR | 1 |
| Bravo, L; Cámara, C; Campuzano, S; Cuello, S; Goya, L; Madrid, Y; Pedrero, M; Ramos, S | 1 |
| Herman, B; Lopez-Cruzan, M; Morgan, WW; Tiwari, M | 1 |
| Adams, DH; Afford, SC; Bhatt, AN; Bhogal, RH; Curbishley, SM; Weston, CJ | 1 |
| Patel, F | 1 |
| Kabiraj, P; Miranda, M; Narayan, M; Pal, R; Varela-Ramirez, A | 1 |
| Cantoni, O; Guidarelli, A; Sestili, P; Tommasini, I | 1 |
| Allain, N; Fardel, O; Lagadic-Gossmann, D; Lemarié, A; Morzadec, C; Vernhet, L | 1 |
| Cooper, JM; Gu, M; Iravani, MM; Irvani, M; Jenner, P; King, D; Schapira, AH | 1 |
| Gille, G; Radad, K; Rausch, WD | 1 |
| An, LJ; Bao, YM; Jiang, B; Liu, YM | 1 |
| Gabai, VL; Kabakov, AE | 1 |
| Cooper, JM; Hartley, A; Heron, C; Schapira, AH; Stone, JM | 1 |
| Bour, ES; Cornman, GA; Isom, HC; Ward, LK | 1 |
| Eguchi, Y; Kamiike, W; Matsuda, H; Shimizu, S; Tsujimoto, Y; Uchiyama, Y; Waguri, S | 1 |
| Brambilla, L; Cantoni, O; Sestili, P | 1 |
| Catisti, R; Vercesi, AE | 1 |
| Leist, M; Nicotera, P; Single, B | 1 |
| Almeida, A; Bolaños, JP | 1 |
| Fariss, MW; Nicholls-Grzemski, FA; Tirmenstein, MA; Zhang, JG | 1 |
28 other study(ies) available for rotenone and Necrosis
| Article | Year |
|---|---|
Curcumin neuroprotective effects in Parkinson disease during pregnancy.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Curcumin; Female; Mice; MicroRNAs; Necrosis; Neuroprotective Agents; Parkinson Disease; Pregnancy; Proto-Oncogene Proteins c-bcl-2; RNA, Circular; Rotenone | 2023 |
Rotenone-induced necrosis in insect cells via the cytoplasmic membrane damage and mitochondrial dysfunction.
Topics: Animals; Apoptosis; Cell Membrane; Membrane Potential, Mitochondrial; Mitochondria; Necrosis; Rotenone | 2021 |
3-Methyladenine prevents energy stress-induced necrotic death of melanoma cells through autophagy-independent mechanisms.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Autophagy; Cell Death; Deoxyglucose; JNK Mitogen-Activated Protein Kinases; Mechanistic Target of Rapamycin Complex 1; Melanoma; Melanoma, Experimental; Mice, Inbred C57BL; Mitochondria; Mitochondrial Swelling; Necrosis; Oxidative Stress; Phosphatidylinositol 3-Kinases; Rotenone | 2021 |
Necrosis, apoptosis, necroptosis, three modes of action of dopaminergic neuron neurotoxins.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Apoptosis; Cells, Cultured; Dopaminergic Neurons; Embryo, Mammalian; Energy Metabolism; Female; Humans; Mesencephalon; Mitochondria; Necroptosis; Necrosis; Neurotoxins; Oxidative Stress; Oxidopamine; Parkinson Disease; Primary Cell Culture; Protein Aggregation, Pathological; Rats; Rotenone | 2019 |
NAD(+) treatment prevents rotenone-induced apoptosis and necrosis of differentiated PC12 cells.
Topics: Animals; Apoptosis; Cell Differentiation; Insecticides; Membrane Potential, Mitochondrial; NAD; Necrosis; PC12 Cells; Rats; Rotenone | 2014 |
A combination of curcumin with either gramicidin or ouabain selectively kills cells that express the multidrug resistance-linked ABCG2 transporter.
Topics: Adenosine Triphosphate; Antimycin A; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caspase 3; Caspase 7; Curcumin; Drug Combinations; Drug Resistance, Multiple; Flow Cytometry; Gramicidin; HEK293 Cells; Humans; Hydrolysis; MCF-7 Cells; Membrane Potentials; Necrosis; Neoplasm Proteins; Ouabain; Patch-Clamp Techniques; Rotenone | 2014 |
Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Blotting, Western; Cells, Cultured; Electron Transport Complex I; Electron Transport Complex II; Embryo, Mammalian; Fibroblasts; Galactose; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mice, Knockout; Mitochondria; Necrosis; Neurons; Reactive Oxygen Species; Rotenone; Succinates; Superoxides | 2014 |
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carrier Proteins; Caspases; Cell Line, Tumor; Chromatin; Colchicine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Microfilament Proteins; Necrosis; Neurons; Nocodazole; Peptidomimetics; Quinolines; Rotenone; Signal Transduction; Staurosporine; Thapsigargin | 2015 |
Bax shuttling after rotenone treatment of neuronal primary cultures: effects on cell death phenotypes.
Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Hypoxia-Ischemia, Brain; Microfilament Proteins; Necrosis; Neurons; Neuroprotective Agents; Organelles; Phenotype; Protein Transport; Rats; Rats, Wistar; Rotenone; Signal Transduction; Uncoupling Agents | 2009 |
Molecular mechanisms of methylmercury-induced cell death in human HepG2 cells.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Survival; Environmental Pollutants; Enzyme Activation; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Methylmercury Compounds; Necrosis; Oxidative Stress; Oxidoreductases; Rotenone; Time Factors; Uncoupling Agents | 2010 |
Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons.
Topics: Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 2; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytochromes c; Gene Knockdown Techniques; Mice; Mice, Knockout; Mitochondria; Necrosis; Neurons; Oxidative Stress; Rotenone; Uncoupling Agents | 2011 |
Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H-R).
Topics: Apoptosis; Cell Hypoxia; Cell Size; Cells, Cultured; Flow Cytometry; Hepatocytes; Humans; Mitochondria; Necrosis; Oxygen; Reactive Oxygen Species; Rotenone; Uncoupling Agents | 2011 |
Pesticidal suicide: adult fatal rotenone poisoning.
Topics: Chromatography, High Pressure Liquid; Female; Forensic Pathology; Forensic Toxicology; Humans; India; Insecticides; Liver; Lung; Middle Aged; Multiple Organ Failure; Necrosis; Pulmonary Edema; Rotenone; Suicide; Tandem Mass Spectrometry | 2011 |
Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-β-hydroxybutyrate intervention.
Topics: 3-Hydroxybutyric Acid; Apoptosis; Carrier Proteins; Caspases; Cell Line, Tumor; Dopaminergic Neurons; Green Fluorescent Proteins; Humans; Mitochondrial Diseases; Necrosis; Nerve Tissue Proteins; Neuroprotective Agents; Nitrates; Nitrosation; Oxidative Stress; Parkinson Disease; Protein Folding; Rotenone | 2012 |
Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2.
Topics: Antimycin A; Arachidonic Acid; Blotting, Western; Catalase; Cell Death; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Immunohistochemistry; Microscopy, Confocal; Mitochondria; Necrosis; Oligonucleotides; Oligonucleotides, Antisense; Oxygen Consumption; Peroxynitrous Acid; Phospholipases A; Phospholipases A2; Rotenone; Signal Transduction; Temperature; Transfection; U937 Cells | 2004 |
Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor.
Topics: Active Transport, Cell Nucleus; Apoptosis; bcl-X Protein; Blotting, Northern; Blotting, Western; Cadmium; Calcium; Caspases; Cell Line; Chelating Agents; Cytoplasm; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Endodeoxyribonucleases; Humans; Liver; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Necrosis; NF-kappa B; Onium Compounds; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA; Rotenone; Ruthenium Red; Time Factors; Uncoupling Agents | 2004 |
Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.
Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Antioxidants; Benzothiazoles; Carbocyanines; Caspase 3; Caspases; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; Humans; Jurkat Cells; L-Lactate Dehydrogenase; Mitochondria; Necrosis; Neuroblastoma; Pramipexole; Rotenone; Thiazoles | 2004 |
Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration.
Topics: Animals; Apoptosis; Benzimidazoles; Cell Death; Cell Survival; Cells, Cultured; Culture Media; Dopamine; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; Immunohistochemistry; L-Lactate Dehydrogenase; Lactic Acid; Membrane Potentials; Mesencephalon; Mice; Mitochondria; Necrosis; Neurons; Oxygen Consumption; Pregnancy; Reactive Oxygen Species; Rotenone; Superoxides; Tyrosine 3-Monooxygenase; Uncoupling Agents | 2006 |
Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Nucleus; Cell Survival; Dopamine; Flow Cytometry; Genes, bcl-2; Glutathione; Hydroxybenzoates; Membrane Potentials; Mitochondria; Necrosis; Neurotoxicity Syndromes; PC12 Cells; Rats; Reactive Oxygen Species; Rotenone; Uncoupling Agents | 2008 |
Heat shock-induced accumulation of 70-kDa stress protein (HSP70) can protect ATP-depleted tumor cells from necrosis.
Topics: Adenosine Triphosphate; Animals; Cycloheximide; Hot Temperature; HSP70 Heat-Shock Proteins; Ischemia; Mice; Necrosis; Protein Synthesis Inhibitors; Rotenone; Tumor Cells, Cultured | 1995 |
Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Dose-Response Relationship, Drug; Electron Transport Complex I; NADH, NADPH Oxidoreductases; Necrosis; Parkinson Disease; PC12 Cells; Rats; Rotenone; Substantia Nigra | 1994 |
Tumor necrosis factor-alpha-induced apoptosis in hepatocytes in long-term culture.
Topics: Animals; Apoptosis; Cell Culture Techniques; Culture Media; Dimethyl Sulfoxide; DNA; Electrophoresis, Agar Gel; Liver; Male; Necrosis; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Rotenone; Tumor Necrosis Factor-alpha | 1996 |
Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions.
Topics: Amino Acid Sequence; Animals; Antimycin A; Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Caspase 1; Cell Death; Cell Hypoxia; Cysteine Endopeptidases; DNA, Complementary; Humans; Molecular Sequence Data; Necrosis; PC12 Cells; Potassium Cyanide; Protease Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rotenone; Signal Transduction; Transfection; Tumor Cells, Cultured | 1996 |
Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate.
Topics: Apoptosis; Cell Count; Cell Division; Cell Survival; Cyclosporine; DNA Fragmentation; Enzyme Inhibitors; Humans; Kinetics; Necrosis; Pyruvic Acid; Rotenone; tert-Butylhydroperoxide; Time Factors; U937 Cells; Uncoupling Agents | 1999 |
The participation of pyridine nucleotides redox state and reactive oxygen in the fatty acid-induced permeability transition in rat liver mitochondria.
Topics: Animals; Apoptosis; Arachidonic Acid; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Electrophysiology; Fatty Acids; Female; Membrane Potentials; Mitochondria, Liver; NADP; Necrosis; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Wistar; Reactive Oxygen Species; Rotenone; Uncoupling Agents | 1999 |
Differential effects of bcl-2 on cell death triggered under ATP-depleting conditions.
Topics: Adenosine Triphosphate; Apoptosis; Cytochrome c Group; Glutathione; Humans; Intracellular Membranes; Jurkat Cells; Mitochondria; Necrosis; Nitric Oxide; Nitroso Compounds; Proto-Oncogene Proteins c-bcl-2; Rotenone; S-Nitrosoglutathione; Staurosporine; Time Factors | 2001 |
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Cyclosporine; Electron Transport; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Membrane Potentials; Mitochondria; Models, Biological; NAD; NADH, NADPH Oxidoreductases; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligomycins; omega-N-Methylarginine; Permeability; Rats; Rats, Wistar; Receptors, Glutamate; Rotenone; Single-Blind Method; Succinate Cytochrome c Oxidoreductase | 2001 |
Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents.
Topics: Animals; Antimycin A; Antioxidants; Cell Survival; Cells, Cultured; Drug Antagonism; Electron Transport; Enzyme Inhibitors; Ethyl Methanesulfonate; Hepatocytes; Lipid Peroxidation; Male; Mitochondria; Necrosis; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rotenone; Thenoyltrifluoroacetone; Tocopherols; Vitamin E | 2001 |