Page last updated: 2024-08-17

rotenone and Mitochondrial Diseases

rotenone has been researched along with Mitochondrial Diseases in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (44.00)29.6817
2010's9 (36.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Adant, I; Bird, M; Cassiman, D; de Witte, P; Decru, B; Ghesquière, B; Rymen, D; Vermeersch, P; Wallays, M; Windmolders, P; Witters, P1
Chakraborty, S; Dey, P; Dutta, S; Mukherjee, P; Sarkar, A; Sur, M1
Cui, XS; Nie, ZW; Niu, YJ; Shin, KT; Zhou, W1
Goto, S; Karube, Y; Koga, M; Matsunaga, K; Murata, A; Setoguchi, S; Takata, J; Terada, K; Toki, E; Watase, D; Yamakawa, H1
Bhurtel, S; Choi, DY; Katila, N; Park, PH1
Bénit, P; Diogo, CV; Fernández-Mosquera, L; Lopez, LC; Luna Sánchez, M; Milosevic, I; Raimundo, N; Rustin, P; Santos, GL; Yambire, KF1
He, D; Lei, L; Liu, M; Lou, D; Lu, S; Shi, Y; Song, Y; Wang, Z; Wu, S1
Eiroa, HD; García Samartino, C; Loos, MA; Lubieniecki, F; Marzese, DM; Mayorga, L; Romano, PS; Roqué, M; Salassa, BN1
Black, JA; Estacion, M; Kim, I; Persson, AK; Waxman, SG; Zhao, P1
Cannon, JR; Greenamyre, JT; Tapias, V1
Feng, Z; Hao, J; Jia, H; Li, X; Liu, J; Liu, Z; Shen, W; Zhang, H1
Hayashi, Y; Ide, T; Kang, D; Kanki, T; Nakanishi, H; Ochi-Shindou, M; Sunagawa, K; Tsutsui, H; Wu, Z; Yamato, M; Yoshida, M1
Abou-Sleiman, P; Bandmann, O; Cookson, MR; Klaffke, S; Koopman, WJ; Mortiboys, H; Olpin, S; Smeitink, JA; Thomas, KJ; Willems, PH; Wood, NW1
Chomova, M; Dobrota, D; Hatok, J; Kaplan, P; Racay, P; Tatarkova, Z1
Daniels, WM; Hattingh, S; Pienaar, IS; Schallert, T1
Dieteren, CE; Koopman, WJ; Nijtmans, LG; Roestenberg, P; Smeitink, JA; Valsecchi, F; Willems, PH1
Arnold, B; Berman, SB; Cassady, SJ; VanLaar, VS1
Kabiraj, P; Miranda, M; Narayan, M; Pal, R; Varela-Ramirez, A1
Bottoni, P; Giardina, B; Martorana, GE; Scatena, R1
Leshem, D; Shainberg, A; Shmist, Y; Shneyvays, V; Zinman, T1
Aquilano, K; Ciriolo, MR; Rotilio, G; Vigilanza, P1
Koopman, WJ; Nijtmans, LG; Smeitink, JA; van Emst-de Vries, S; Verkaart, S; Visch, HJ; Willems, PH1
Cheek, J; Koopman, WJ; Smeitink, JA; van den Heuvel, LW; van Emst-de Vries, SE; Verkaart, S; Willems, PH1
Milbrandt, J; Press, C1
Gonzalez-Lima, F; Jones, D; Zhang, X1

Reviews

3 review(s) available for rotenone and Mitochondrial Diseases

ArticleYear
Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.
    Antioxidants & redox signaling, 2010, Jun-15, Volume: 12, Issue:12

    Topics: Animals; Biological Transport; Cattle; Chromans; Electron Transport; Electron Transport Complex I; Eukaryotic Cells; Fibroblasts; Humans; Mammals; Membrane Lipids; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; NADH Dehydrogenase; Organ Specificity; Oxidative Phosphorylation; Reactive Oxygen Species; Rotenone; Signal Transduction

2010
Mitochondrial dysfunction by synthetic ligands of peroxisome proliferator activated receptors (PPARs).
    IUBMB life, 2004, Volume: 56, Issue:8

    Topics: Animals; Humans; Hypoglycemic Agents; Ligands; Lipid Metabolism; Liver; Mitochondria; Mitochondrial Diseases; Models, Biological; Neoplasms; PPAR alpha; PPAR gamma; Protein Binding; Rotenone; Thiazolidinediones

2004
Human NADH:ubiquinone oxidoreductase deficiency: radical changes in mitochondrial morphology?
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:1

    Topics: Cell Line; Child; Cluster Analysis; Electron Transport Complex I; Electrophoresis; Enzyme Inhibitors; Fibroblasts; Genetic Predisposition to Disease; Humans; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microscopy, Video; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Mitochondrial Size; Mutation; Oxidative Phosphorylation; Reactive Oxygen Species; Reproducibility of Results; Rotenone; Severity of Illness Index; Uncoupling Agents

2007

Other Studies

22 other study(ies) available for rotenone and Mitochondrial Diseases

ArticleYear
Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction.
    Molecular metabolism, 2022, Volume: 63

    Topics: Animals; Metabolome; Mitochondrial Diseases; NAD; Oxidative Phosphorylation; Pyruvic Acid; Rotenone; Uridine; Zebrafish

2022
Early loss of endogenous NAD
    The FEBS journal, 2023, Volume: 290, Issue:6

    Topics: Animals; Armadillo Domain Proteins; Drosophila melanogaster; Mitochondria; Mitochondrial Diseases; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Rotenone

2023
Melatonin enhances mitochondrial biogenesis and protects against rotenone-induced mitochondrial deficiency in early porcine embryos.
    Journal of pineal research, 2020, Volume: 68, Issue:2

    Topics: Animals; Embryo, Mammalian; Embryonic Development; Melatonin; Mitochondria; Mitochondrial Diseases; Rotenone; Swine

2020
Atypical Antipsychotic Drug Ziprasidone Protects against Rotenone-Induced Neurotoxicity: An In Vitro Study.
    Molecules (Basel, Switzerland), 2020, Sep-14, Volume: 25, Issue:18

    Topics: Animals; Antioxidants; Antipsychotic Agents; Apoptosis; Cell Death; Cell Nucleus; Cell Survival; Cytoplasm; Mice; Mitochondrial Diseases; Nerve Growth Factor; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; PC12 Cells; Piperazines; Rats; Reactive Oxygen Species; Receptor, Serotonin, 5-HT1A; Rotenone; Thiazoles

2020
Metformin attenuates rotenone-induced oxidative stress and mitochondrial damage via the AKT/Nrf2 pathway.
    Neurochemistry international, 2021, Volume: 148

    Topics: Cell Line; Cell Survival; Humans; Hypoglycemic Agents; Metformin; Mitochondrial Diseases; NF-E2-Related Factor 2; Oncogene Protein v-akt; Oxidative Stress; Reactive Oxygen Species; Rotenone; Signal Transduction; Uncoupling Agents

2021
Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis.
    Scientific reports, 2017, 03-27, Volume: 7

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Electron Transport; HeLa Cells; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Microphthalmia-Associated Transcription Factor; Mitochondria; Mitochondrial Diseases; Organelle Biogenesis; Protein Kinases; Rotenone; Uncoupling Agents

2017
Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism.
    Experimental neurology, 2018, Volume: 309

    Topics: Adenosine Triphosphate; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Green Fluorescent Proteins; Membrane Potential, Mitochondrial; Membrane Proteins; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Movement; Mutation; Paraquat; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone

2018
Mitochondrial stress triggers a pro-survival response through epigenetic modifications of nuclear DNA.
    Cellular and molecular life sciences : CMLS, 2019, Volume: 76, Issue:7

    Topics: Adolescent; Autophagy; Case-Control Studies; Cell Nucleus; Cell Shape; Cell Survival; Cells, Cultured; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Mitochondria; Mitochondrial Diseases; Myoblasts; Rotenone

2019
Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Dec-04, Volume: 33, Issue:49

    Topics: Animals; Axons; Axotomy; Cell Death; Cells, Cultured; Ganglia, Spinal; Humans; Hydrogen Peroxide; Immunohistochemistry; Mice; Mice, Transgenic; Microtubules; Mitochondrial Diseases; Nerve Degeneration; Neurites; Oxidants; Rotenone; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin; Thiourea; Uncoupling Agents

2013
Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:5

    Topics: Animals; Caspase 3; Disease Models, Animal; Dopaminergic Neurons; Inflammation; Lythraceae; Male; Mitochondrial Diseases; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Tyrosine

2014
Synergistic anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model.
    Neurobiology of aging, 2010, Volume: 31, Issue:4

    Topics: alpha-Synuclein; Biomarkers; Cell Line, Tumor; Coenzymes; DNA Damage; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Electron Transport Complex I; Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Models, Biological; Nerve Tissue Proteins; Oxidative Stress; Oxygen Consumption; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Rotenone; Transcription Factors; Ubiquitin; Uncoupling Agents; Vitamin B Complex

2010
Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Aug-20, Volume: 28, Issue:34

    Topics: Aging; Animals; Biological Transport; Brain; DNA Damage; DNA-Binding Proteins; DNA, Mitochondrial; HeLa Cells; Hippocampus; Humans; Intracellular Membranes; Learning; Long-Term Potentiation; Memory; Memory Disorders; Mice; Mice, Transgenic; Microglia; Mitochondrial Diseases; Mitochondrial Proteins; Motor Activity; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Recovery of Function; Rotenone; Transcription Factors; Up-Regulation

2008
Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts.
    Annals of neurology, 2008, Volume: 64, Issue:5

    Topics: Adenosine Triphosphate; Adult; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinical; Electron Transport Chain Complex Proteins; Energy Metabolism; Fibroblasts; Humans; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Mitochondrial Diseases; Mutation; Neuroprotective Agents; Parkinsonian Disorders; Rotenone; Ubiquitin-Protein Ligases; Uncoupling Agents

2008
Mitochondrial calcium transport and mitochondrial dysfunction after global brain ischemia in rat hippocampus.
    Neurochemical research, 2009, Volume: 34, Issue:8

    Topics: Adaptor Protein Complex 1; Adaptor Protein Complex 4; Animals; Azides; Brain Ischemia; Calcium; Ferricyanides; Hippocampus; Male; Membrane Potentials; Membrane Proteins; Mitochondria; Mitochondrial Diseases; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Rotenone; Spectrometry, Fluorescence; Ubiquinone; Uncoupling Agents

2009
Behavioral and quantitative mitochondrial proteome analyses of the effects of simvastatin: implications for models of neural degeneration.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:7

    Topics: Animals; Disease Models, Animal; Electron Transport Chain Complex Proteins; Free Radicals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mass Spectrometry; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotenone; Simvastatin; Substantia Nigra; Uncoupling Agents

2009
Integrating multiple aspects of mitochondrial dynamics in neurons: age-related differences and dynamic changes in a chronic rotenone model.
    Neurobiology of disease, 2011, Volume: 41, Issue:1

    Topics: Aging; Animals; Cells, Cultured; Chronic Disease; Mitochondria; Mitochondrial Diseases; Models, Biological; Neurons; Parkinson Disease; Rats; Rotenone; Substantia Nigra; Uncoupling Agents

2011
Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-β-hydroxybutyrate intervention.
    Biochemical and biophysical research communications, 2012, Sep-28, Volume: 426, Issue:3

    Topics: 3-Hydroxybutyric Acid; Apoptosis; Carrier Proteins; Caspases; Cell Line, Tumor; Dopaminergic Neurons; Green Fluorescent Proteins; Humans; Mitochondrial Diseases; Necrosis; Nerve Tissue Proteins; Neuroprotective Agents; Nitrates; Nitrosation; Oxidative Stress; Parkinson Disease; Protein Folding; Rotenone

2012
Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders.
    Journal of molecular and cellular cardiology, 2005, Volume: 39, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Mitochondrial Diseases; Myocytes, Cardiac; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Rats; Rotenone; Uncoupling Agents; Vitamin K 3

2005
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:10

    Topics: Cell Line, Tumor; Homeostasis; Humans; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Rotenone; Superoxide Dismutase; Superoxide Dismutase-1

2006
Mitochondrial and cytosolic thiol redox state are not detectably altered in isolated human NADH:ubiquinone oxidoreductase deficiency.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:9

    Topics: Adult; Case-Control Studies; Cells, Cultured; Child, Preschool; Cytosol; Electron Transport Complex I; Fibroblasts; Glutathione; Humans; Infant; Infant, Newborn; Lipid Peroxidation; Mitochondria; Mitochondrial Diseases; Oxidation-Reduction; Rotenone; Sulfhydryl Compounds; Uncoupling Agents

2007
Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, May-07, Volume: 28, Issue:19

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Axons; Cells, Cultured; Down-Regulation; Ganglia, Spinal; Gene Transfer Techniques; Isoenzymes; Mitochondrial Diseases; Nerve Degeneration; Neurons; Nicotinamide-Nucleotide Adenylyltransferase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rotenone; Stress, Physiological; Vincristine

2008
Mouse model of optic neuropathy caused by mitochondrial complex I dysfunction.
    Neuroscience letters, 2002, Jun-28, Volume: 326, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Male; Mice; Mice, Inbred CBA; Mitochondria; Mitochondrial Diseases; Optic Nerve Diseases; Pharmaceutical Vehicles; Quinone Reductases; Retinal Ganglion Cells; Rotenone; Time Factors; Uncoupling Agents

2002