Page last updated: 2024-08-17

rotenone and MPTP Neurotoxicity Syndrome

rotenone has been researched along with MPTP Neurotoxicity Syndrome in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's4 (21.05)29.6817
2010's13 (68.42)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Chen, Y; Ding, Y; Lan, JS; Liu, L; Liu, Y; Xie, SS; Yang, J; Yang, YT; Zeng, RF; Zhang, T1
Capps, J; Virga, DM; Vohra, BPS1
Bhurtel, S; Choi, DY; Katila, N; Neupane, S; Srivastav, S1
Bhurtel, S; Choi, DY; Choi, H; Hong, JT; Katila, N; Maharjan, S; Neupane, S; Srivastav, S1
Dagda, RK; Das Banerjee, T; Janda, E1
Li, WW; Lu, CZ; Zhu, M1
Bähr, M; Dohm, CP; Kermer, P; Köhn, A; Liman, J; Lingor, P; Schnieder, M1
Chang, YM; Chen, CH; Chen, CL; Chen, YJ; Chiu, CC; Huang, YC; Lai, SC; Lu, CS; Mochly-Rosen, D; Wang, HL; Wu-Chou, YH; Yeh, TH1
Kostrzewa, RM; Segura-Aguilar, J1
Hotta, K; Oka, K; Shindo, Y; Suzuki, K; Yamanaka, R1
Bähr, M; Dietz, GP; Nagel, F1
Aoki, E; Araki, T; Kato, H; Kimoto, H; Yano, R; Yokoyama, H1
Cannon, JR; Greenamyre, JT1
Tieu, K1
Chesselet, MF; McDowell, K1
Biswas, SC; Greene, LA; Jackson-Lewis, V; Malagelada, C; Ryu, EJ1
Ayala, A; Cano, J; Machado, A; Venero, JL1
Behrouz, B; Drolet, RE; Goudreau, JL; Lookingland, KJ; Sayed, ZA1
Duan, W; Mattson, MP1

Reviews

5 review(s) available for rotenone and MPTP Neurotoxicity Syndrome

ArticleYear
How Parkinsonian toxins dysregulate the autophagy machinery.
    International journal of molecular sciences, 2013, Nov-08, Volume: 14, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Autophagy; Humans; Methamphetamine; Mitophagy; MPTP Poisoning; Neurotoxins; Oxidopamine; Paraquat; Parkinsonian Disorders; Rotenone

2013
Neurotoxic in vivo models of Parkinson's disease recent advances.
    Progress in brain research, 2010, Volume: 184

    Topics: Animals; Disease Models, Animal; Dopamine; Humans; MPTP Poisoning; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Rotenone; Sympatholytics; Uncoupling Agents

2010
A guide to neurotoxic animal models of Parkinson's disease.
    Cold Spring Harbor perspectives in medicine, 2011, Volume: 1, Issue:1

    Topics: Animals; Corpus Striatum; Disease Models, Animal; Haplorhini; Lewy Bodies; Mice; MPTP Poisoning; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rotenone; Substantia Nigra

2011
Animal models of the non-motor features of Parkinson's disease.
    Neurobiology of disease, 2012, Volume: 46, Issue:3

    Topics: alpha-Synuclein; Animals; Disease Models, Animal; Humans; Hydroxydopamines; MPTP Poisoning; Neurotoxins; Parkinson Disease; Parkinson Disease, Secondary; Risk Factors; Rotenone; Uncoupling Agents

2012
Mitochondrial toxins and neurodegenerative diseases.
    Frontiers in bioscience : a journal and virtual library, 2007, Jan-01, Volume: 12

    Topics: Animals; Disease Models, Animal; Humans; Huntington Disease; Mitochondria; MPTP Poisoning; Neurodegenerative Diseases; Nitro Compounds; Parkinson Disease, Secondary; Propionates; Rotenone; Succinate Dehydrogenase; Tetrahydroisoquinolines

2007

Other Studies

14 other study(ies) available for rotenone and MPTP Neurotoxicity Syndrome

ArticleYear
Design and synthesis of novel 3,4-dihydrocoumarins as potent and selective monoamine oxidase-B inhibitors with the neuroprotection against Parkinson's disease.
    Bioorganic chemistry, 2021, Volume: 109

    Topics: Animals; Coumarins; Drug Design; Indans; Mice; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; MPTP Poisoning; Oxidopamine; PC12 Cells; Protein Conformation; Rats; Rotenone; Structure-Activity Relationship

2021
Enteric Neurodegeneration is Mediated Through Independent Neuritic and Somal Mechanisms in Rotenone and MPP+ Toxicity.
    Neurochemical research, 2018, Volume: 43, Issue:12

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Enteric Nervous System; Female; Insecticides; Mice; MPTP Poisoning; Nerve Degeneration; Neurites; Parkinson Disease, Secondary; Parkinsonian Disorders; Pregnancy; Rotenone

2018
Mechanistic comparison between MPTP and rotenone neurotoxicity in mice.
    Neurotoxicology, 2019, Volume: 71

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Brain; Dopamine; Male; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Parkinsonian Disorders; Rotenone

2019
Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity.
    The Journal of nutritional biochemistry, 2019, Volume: 69

    Topics: Acetylation; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Butyrates; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Glial Cell Line-Derived Neurotrophic Factor; Histones; Male; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Neuroglia; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Probiotics; Rotenone

2019
Histone decacetylase inhibitors prevent mitochondrial fragmentation and elicit early neuroprotection against MPP+.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; GTP Phosphohydrolases; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; MPTP Poisoning; Neuroprotective Agents; Parkinsonian Disorders; Rotenone; Uncoupling Agents

2014
BAG1 is neuroprotective in in vivo and in vitro models of Parkinson's disease.
    Journal of molecular neuroscience : MN, 2015, Volume: 55, Issue:3

    Topics: alpha-Synuclein; Animals; Apoptosis; Cell Line, Tumor; DNA-Binding Proteins; Humans; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Oxidopamine; Rotenone; Substantia Nigra; Transcription Factors

2015
Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism.
    Experimental neurology, 2015, Volume: 263

    Topics: Aldehyde Dehydrogenase; Animals; Benzamides; Benzodioxoles; Cell Line; Disease Models, Animal; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Microscopy, Confocal; MPTP Poisoning; Neurons; Parkinsonian Disorders; Rats; Reactive Oxygen Species; Rotenone; Uncoupling Agents

2015
Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.
    Neurotoxicity research, 2015, Volume: 27, Issue:3

    Topics: Animals; Brain; Dopaminergic Neurons; Encephalitis; Humans; Mitochondria; MPTP Poisoning; Neurons; Oxidative Stress; Oxidopamine; Parkinson Disease, Secondary; Rotenone; Signal Transduction

2015
Altered expression of Mg(2+) transport proteins during Parkinson's disease-like dopaminergic cell degeneration in PC12 cells.
    Biochimica et biophysica acta, 2016, Volume: 1863, Issue:8

    Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cation Transport Proteins; Cell Differentiation; Hydrogen Peroxide; Ion Transport; Magnesium; Membrane Potential, Mitochondrial; Mitochondria; MPTP Poisoning; Nerve Degeneration; Nerve Growth Factor; PC12 Cells; Rats; RNA Interference; RNA, Messenger; RNA, Small Interfering; Rotenone

2016
Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins.
    Brain research bulletin, 2009, Jun-30, Volume: 79, Issue:5

    Topics: Amacrine Cells; Animals; Astrocytes; Cell Death; Cell Survival; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Eye; Gliosis; Male; Mesencephalon; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Oxidopamine; Rotenone; Tyrosine 3-Monooxygenase

2009
Chronic administration with rotenone does not enhance MPTP neurotoxicity in C57BL/6 mice.
    Journal of molecular neuroscience : MN, 2010, Volume: 41, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Dopamine; Dopamine Agents; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuropsychological Tests; Rotenone; Uncoupling Agents

2010
RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-27, Volume: 26, Issue:39

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Camptothecin; DNA-Binding Proteins; Gene Expression Regulation; Humans; Hydrogen Peroxide; Male; Melanins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Growth Factor; Neurons; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Rats; Repressor Proteins; Ribosomal Protein S6 Kinases, 70-kDa; RNA; RNA Interference; Rotenone; Signal Transduction; Substantia Nigra; TOR Serine-Threonine Kinases; Transcription Factors; Transcription, Genetic; Transfection; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Tunicamycin

2006
Unique responses to mitochondrial complex I inhibition in tuberoinfundibular dopamine neurons may impart resistance to toxic insult.
    Neuroscience, 2007, Jul-13, Volume: 147, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Animals, Newborn; Apoptosis; Arcuate Nucleus of Hypothalamus; Brain Chemistry; Brain Stem; Cell Count; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Electron Transport Complex I; Male; Mice; MPTP Poisoning; Neurons; Neurotoxins; Rotenone; Tyrosine 3-Monooxygenase

2007
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.
    Journal of neuroscience research, 1999, Jul-15, Volume: 57, Issue:2

    Topics: Animals; Antimetabolites; Apoptosis; Behavior, Animal; Carrier Proteins; Corpus Striatum; Deoxyglucose; Disease Models, Animal; Dopamine; Dopamine Agents; Endoplasmic Reticulum Chaperone BiP; Energy Intake; Ferrous Compounds; Heat-Shock Proteins; Heat-Shock Response; HSP70 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL; Mitochondria; Molecular Chaperones; MPTP Poisoning; Nerve Degeneration; Neurons; Parkinson Disease, Secondary; Reactive Oxygen Species; Rotenone; Substantia Nigra; Uncoupling Agents

1999