Page last updated: 2024-08-17

rotenone and Lung Neoplasms

rotenone has been researched along with Lung Neoplasms in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.41)18.2507
2000's13 (35.14)29.6817
2010's19 (51.35)24.3611
2020's3 (8.11)2.80

Authors

AuthorsStudies
Cui, D; Lu, G; Yao, Y; Zhang, X; Zhou, J1
Gao, F; Li, M; Li, W; Liu, H; Liu, W; Yu, X; Zhou, L1
Dong, Y; Ma, X; Xu, J; Xu, S; Zhou, H1
Dong, X; Gao, F; Li, W; Ma, X; Wang, R; Wang, W1
Chen, Y; Cui, D; Han, W; Liu, X; Zhao, D1
Bi, Y; Chen, Y; Ma, F; Wang, A; Wang, W; Wei, X1
Chen, JC; Chung, JG; Fan, MJ; Hsia, TC; Hsiao, YT; Huang, AC; Lien, JC; Lin, JJ; Wu, RS1
Gauthier, C; Legault, J; Mihoub, M; Pichette, A; Sylla, B1
Li, W; Liu, H; Liu, L; Ma, X; Wang, J; Xia, Z; Xie, L; Yang, Y; Yu, X; Zhou, H; Zhou, X1
Alimirah, F; Gupta, A; Kalra, A; Katta, H; Mehta, RG; Mehta, RR; Murillo, G; Muzzio, M; Patel, R; Peng, X; Unni, A1
Bian, JJ; Chen, W; Feng, S; Hua, ZC; Shi, YL; Yin, W1
Choi, H; Hong, HS; Kim, H; Kim, HS; Kim, KC; Kim, KW; Lee, HY; Lee, J; Lee, MY; Lee, SC; Min, HY; Park, HJ; Park, SJ; Seo, JH; Seong, MA; Suh, YG1
Lee, D; Lee, HE; Lee, HY; Lee, SH; Lee, YM; Nguyen, MP1
Chiang, JH; Chung, JG; Hsia, TC; Hsu, YC; Lai, KC; Lien, JC; Wu, RS; Yu, CS; Yu, FS1
Jiao, Y; Zhang, Z; Zhao, H1
Gao, C; Hao, B; Hu, W; Li, L; Li, S; Lu, M; Qi, L; Shan, S; Si, L; Tian, H; Yue, W1
Bao, Z; Lu, G; Yan, B; Yao, Y; Zhao, D; Zhou, J1
Guan, C; He, H; Peng, Y; Wu, X; Xu, Z; Yang, J; Zhong, H; Zuo, Y1
Chang, DJ; Geo, SY; Han, SH; Hennessy, B; Hong, WK; Kang, HJ; Kim, KW; Kim, WY; Kim, YS; Lee, HY; Mills, G; Park, HJ; Seo, SY; Suh, YG; Yoo, J1
Choi, DS; Gilbert, BE; Hong, WK; Lee, HY; Tran, HT; Woo, JK1
Dennis, PA; Memmott, RM1
Jonas, L; Kashyap, MP; Kumar, V; Lohani, M; Pant, AB; Rahman, Q; Srivastava, RK1
Chung, JG; Hsia, TC; Ji, BC; Ko, YC; Lai, KC; Lai, TY; Lin, JJ; Yang, JS; Yang, ST; Yu, CC1
Crowell, JA; Steele, VE1
Chun, KH; Hong, WK; Kosmeder, JW; Lee, HY; Lotan, R; Pezzuto, JM; Sun, S1
Hong, WK; Kosmeder, JW; Kurie, JM; Lee, HY; Pezzuto, JM; Suh, YA1
Adeyeye, MC; Gibbs, JP; Shen, DD; Yang, Z1
Lee, HY1
Hecht, SS1
Cody, D; Hong, WK; Kim, WY; Lee, HY; Moriarty, RM; Oh, SH; Pezzuto, JM; Price, RE; Tran, H; Van Pelt, CS; Woo, JK1
Lubet, RA; Tan, Q; Wang, Y; Yan, Y; You, M1
Behrens, C; Bekele, BN; Feng, L; Hong, WK; Jin, Q; Lee, HY; Wistuba, II1
Alho, JM; Valtonen, E1
Eberl, T; Fuchs, A; Gnaiger, E; Hengster, P; Kuznetsov, A; Lassnig, B; Margreiter, R; Rieger, G; Stadlmann, S1
Li, B; Liu, R; Qiu, M1
Metzen, E; Ratcliffe, PJ; Vaux, EC; Yeates, KM1
Ausawasamrit, A; Chanvorachote, P; Chaotham, C; Itthiwarapornkul, N; Sukrong, S1

Other Studies

37 other study(ies) available for rotenone and Lung Neoplasms

ArticleYear
Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway.
    Disease markers, 2022, Volume: 2022

    Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Lung Neoplasms; Mice; Neoplasm Metastasis; PTEN Phosphohydrolase; Rotenone; Signal Transduction

2022
Deguelin suppresses non-small cell lung cancer by inhibiting EGFR signaling and promoting GSK3β/FBW7-mediated Mcl-1 destabilization.
    Cell death & disease, 2020, 02-21, Volume: 11, Issue:2

    Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; F-Box-WD Repeat-Containing Protein 7; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Mice, Nude; Mutation; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Protein Kinase Inhibitors; Protein Stability; Rotenone; Signal Transduction; Tumor Burden; Ubiquitination; Xenograft Model Antitumor Assays

2020
Development of a novel truncated deguelin derivative possessing nitric oxide donor as a potential anti-lung cancer agent.
    Fitoterapia, 2020, Volume: 146

    Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Molecular Structure; Nitric Oxide Donors; Rotenone

2020
Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis.
    Oncotarget, 2017, May-16, Volume: 8, Issue:20

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Down-Regulation; Glycolysis; Hexokinase; Humans; Lung Neoplasms; Mice; Rotenone

2017
Deguelin inhibits epithelial-to-mesenchymal transition and metastasis of human non-small cell lung cancer cells by regulating NIMA-related kinase 2.
    Thoracic cancer, 2017, Volume: 8, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Metastasis; NIMA-Related Kinases; Rotenone

2017
Deguelin induces PUMA-mediated apoptosis and promotes sensitivity of lung cancer cells (LCCs) to doxorubicin (Dox).
    Molecular and cellular biochemistry, 2018, Volume: 442, Issue:1-2

    Topics: A549 Cells; Apoptosis; Apoptosis Regulatory Proteins; Doxorubicin; Humans; Lung Neoplasms; Proto-Oncogene Proteins; Rotenone

2018
Deguelin Impairs Cell Adhesion, Migration and Invasion of Human Lung Cancer Cells through the NF-[Formula: see text]B Signaling Pathways.
    The American journal of Chinese medicine, 2018, Volume: 46, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Gene Expression; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Rotenone; Signal Transduction

2018
Bidesmosidic betulin saponin bearing L-rhamnopyranoside moieties induces apoptosis and inhibition of lung cancer cells growth in vitro and in vivo.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: A549 Cells; Animals; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Electron Transport Chain Complex Proteins; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Reactive Oxygen Species; Rhamnose; Rotenone; Saponins; Transplantation, Heterologous; Triterpenes

2018
Deguelin attenuates non-small cell lung cancer cell metastasis through inhibiting the CtsZ/FAK signaling pathway.
    Cellular signalling, 2018, Volume: 50

    Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cathepsin Z; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Metastasis; Rotenone; Signal Transduction

2018
Efficacy and mechanism of action of Deguelin in suppressing metastasis of 4T1 cells.
    Clinical & experimental metastasis, 2013, Volume: 30, Issue:7

    Topics: Animals; Cell Division; Cell Line, Tumor; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Rotenone

2013
Mitochondrial inhibitor sensitizes non-small-cell lung carcinoma cells to TRAIL-induced apoptosis by reactive oxygen species and Bcl-X(L)/p53-mediated amplification mechanisms.
    Cell death & disease, 2014, Dec-18, Volume: 5

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Humans; Lung Neoplasms; Mice; Mitochondria; Proto-Oncogene Proteins; Reactive Oxygen Species; Rotenone; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53

2014
Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.
    Molecular pharmacology, 2015, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzopyrans; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Mice; Mice, SCID; Quinolines; Rotenone; Signal Transduction; Xenograft Model Antitumor Assays

2015
Deguelin inhibits vasculogenic function of endothelial progenitor cells in tumor progression and metastasis via suppression of focal adhesion.
    Oncotarget, 2015, Jun-30, Volume: 6, Issue:18

    Topics: Actins; Angiogenesis Inhibitors; Animals; Apoptosis; Carcinogenesis; Carcinoma, Lewis Lung; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemoprevention; Endothelial Progenitor Cells; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; G1 Phase Cell Cycle Checkpoints; Green Fluorescent Proteins; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Protein Serine-Threonine Kinases; Rotenone; Xenograft Model Antitumor Assays

2015
Antitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo: Roles of apoptotic cell death and H460 tumor xenografts model.
    Environmental toxicology, 2017, Volume: 32, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Calcium; Caspase 3; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Rotenone; Xenograft Model Antitumor Assays

2017
Deguelin inhibits the migration and invasion of lung cancer A549 and H460 cells via regulating actin cytoskeleton rearrangement.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:12

    Topics: Actin Cytoskeleton; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Pseudopodia; rac1 GTP-Binding Protein; rho-Associated Kinases; Rotenone; Signal Transduction

2015
Rotenone induces apoptosis in human lung cancer cells by regulating autophagic flux.
    IUBMB life, 2016, Volume: 68, Issue:5

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Autophagy; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mechanistic Target of Rapamycin Complex 1; Membrane Glycoproteins; Multiprotein Complexes; NADPH Oxidase 2; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Rotenone; TOR Serine-Threonine Kinases

2016
Deguelin Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells through Regulating the Expression of Galectin-1.
    International journal of biological sciences, 2016, Volume: 12, Issue:7

    Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Female; Galectin 1; Humans; Immunoblotting; Immunoprecipitation; Lung Neoplasms; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; Rotenone; Signal Transduction

2016
[Synergistic Antitumor Effect of Amorphigenin Combined with Cisplatin in Human Lung Adenocarcinoma A549/DDP Cells].
    Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2016, Dec-20, Volume: 19, Issue:12

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Proliferation; Cisplatin; Drug Synergism; Humans; Lung Neoplasms; Plant Extracts; Poly(ADP-ribose) Polymerases; Rotenone

2016
A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemoprevention; Gene Expression; Humans; Lung Neoplasms; Rotenone; Signal Transduction

2008
Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:4

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatography, High Pressure Liquid; Genes, ras; Humans; Immunohistochemistry; Liposomes; Lung Neoplasms; Mice; Mice, Mutant Strains; Precancerous Conditions; Rotenone; Tissue Distribution

2009
The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Jan-01, Volume: 16, Issue:1

    Topics: Animals; Carcinogens; Humans; Indoles; Inositol; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Nicotiana; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rotenone; Signal Transduction; Sirolimus; Smoking; TOR Serine-Threonine Kinases

2010
Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549.
    Nanotoxicology, 2011, Volume: 5, Issue:2

    Topics: Animals; Apoptosis; Biomarkers; Cell Line, Tumor; Humans; Lung Neoplasms; Mitochondria; Nanotubes, Carbon; Oxidative Stress; Reactive Oxygen Species; Rotenone; Uncoupling Agents

2011
Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells.
    Oncology reports, 2012, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Line, Tumor; Comet Assay; DNA Damage; DNA Modification Methylases; DNA Repair Enzymes; DNA Topoisomerases, Type I; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Agar Gel; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Nuclear Proteins; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; RNA, Messenger; Rotenone; Time Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2012
AKT and the phosphatidylinositol 3-kinase/AKT pathway: important molecular targets for lung cancer prevention and treatment.
    Journal of the National Cancer Institute, 2003, Feb-19, Volume: 95, Issue:4

    Topics: Antineoplastic Agents; Cell Cycle; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rotenone; Signal Transduction; Tumor Cells, Cultured

2003
Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells.
    Journal of the National Cancer Institute, 2003, Feb-19, Volume: 95, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Bronchial Neoplasms; Cell Cycle; Cells, Cultured; Drug Screening Assays, Antitumor; Genetic Vectors; Humans; Immunoblotting; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Respiratory Mucosa; Rotenone; Signal Transduction; Tumor Cells, Cultured

2003
Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-01, Volume: 10, Issue:3

    Topics: Apoptosis; Blotting, Western; Bronchi; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Immunoblotting; Isoenzymes; Lung Neoplasms; Male; Membrane Proteins; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rotenone; Time Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2004
Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport.
    Epilepsy research, 2004, Volume: 58, Issue:1

    Topics: Adenocarcinoma; Animals; Biological Transport, Active; Brain; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Dinitrophenols; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Fluoresceins; GABA Agents; Humans; Indomethacin; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Pancreatic Neoplasms; Probenecid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotenone; Temperature; Tritium; Uncoupling Agents; Uricosuric Agents; Valproic Acid

2004
Molecular mechanisms of deguelin-induced apoptosis in transformed human bronchial epithelial cells.
    Biochemical pharmacology, 2004, Sep-15, Volume: 68, Issue:6

    Topics: Apoptosis; Cell Survival; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rotenone; Tumor Cells, Cultured

2004
Deguelin as a chemopreventive agent in mouse lung tumorigenesis induced by tobacco smoke carcinogens.
    Journal of the National Cancer Institute, 2005, Nov-16, Volume: 97, Issue:22

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Mice; Mice, Transgenic; Nitrosamines; Proto-Oncogene Proteins c-akt; Respiratory Mucosa; Rotenone; Smoking; Tobacco Smoke Pollution

2005
Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.
    Journal of the National Cancer Institute, 2005, Nov-16, Volume: 97, Issue:22

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Bronchial Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Enzyme Activation; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Transgenic; Nitrosamines; Proto-Oncogene Proteins c-akt; Respiratory Mucosa; Rotenone; Smoking; Tobacco Smoke Pollution

2005
Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:12

    Topics: Adenoma; Administration, Oral; Animals; Benzo(a)pyrene; Disease Models, Animal; Lung Neoplasms; Mice; Mice, Inbred A; Rotenone; Silybin; Silybum marianum; Silymarin

2005
Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.
    Cancer research, 2007, Dec-15, Volume: 67, Issue:24

    Topics: AMP-Activated Protein Kinases; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Microtubule-Associated Proteins; Multienzyme Complexes; Neoplasm Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Rotenone; Survivin; Transfection; Uncoupling Agents

2007
Interval estimation of inverse dose-response.
    Biometrics, 1995, Volume: 51, Issue:2

    Topics: Adult; Animals; Bias; Biometry; Confidence Intervals; Dose-Response Relationship, Drug; Esophageal Neoplasms; Humans; Incidence; Lethal Dose 50; Lung Neoplasms; Models, Statistical; Pharmacology; Poisson Distribution; Probability; Regression Analysis; Rotenone; Smoking; Software; Toxicology

1995
Mitochondrial ischemia-reoxygenation injury and plasma membrane integrity in human endothelial cells.
    Transplantation proceedings, 1997, Volume: 29, Issue:8

    Topics: Adenosine; Allopurinol; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Digitonin; Glucose; Glutathione; Humans; Insulin; Lung Neoplasms; Mannitol; Mitochondria; Organ Preservation Solutions; Oxygen Consumption; Potassium Chloride; Procaine; Raffinose; Reperfusion Injury; Rotenone; Tumor Cells, Cultured; Umbilical Veins

1997
Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha.
    Oncogene, 2001, Mar-22, Volume: 20, Issue:12

    Topics: Acetophenones; Allopurinol; Cell Division; Cell Line, Transformed; Cell Movement; Drug Resistance; Enzyme Activation; Genes, ras; Genistein; Humans; Lung Neoplasms; Membrane Proteins; Models, Biological; NADPH Oxidases; Onium Compounds; Oxypurinol; Protein Kinase Inhibitors; Rotenone; Superoxides; Tumor Necrosis Factor-alpha

2001
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.
    Blood, 2001, Jul-15, Volume: 98, Issue:2

    Topics: Animals; Cell Hypoxia; Cell Line; CHO Cells; Cricetinae; Cricetulus; DNA-Binding Proteins; DNA, Mitochondrial; Electron Transport; Ethidium; Gene Expression Regulation; Glucose Transporter Type 1; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mitochondria; Monosaccharide Transport Proteins; Nuclear Proteins; Osteosarcoma; Oxygen Consumption; Polymerase Chain Reaction; Rotenone; Transcription Factors; Tumor Cells, Cultured

2001
Lupalbigenin from Derris scandens Sensitizes Detachment-induced Cell Death in Human Lung Cancer Cells.
    Anticancer research, 2015, Volume: 35, Issue:5

    Topics: Anoikis; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Derris; Gene Expression Regulation, Neoplastic; Humans; Isoflavones; Lung Neoplasms; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2015