rotenone has been researched along with Hereditary Optic Neuroretinopathy in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Carelli, V; Degli Esposti, M; Ghelli, AM; Iommarini, L; Musiani, F; Rigobello, L | 1 |
| Chen, CY; Chen, SP; Chien, Y; Chiou, SH; Hsiao, YJ; Lai, WY; Lin, TC; Lin, YY; Liu, YH; Peng, SY; Tsai, ET; Tseng, HC; Tseng, YH; Wu, YR; Yang, YP | 1 |
| Aoshima, K; Aoyama, Y; Hara, H; Inagaki, S; Iwata, Y; Nakamura, S; Shimazawa, M | 1 |
| Bayona-Bafaluy, MP; Emperador, S; Hernández-Ainsa, C; López-Gallardo, E; Montoya, J; Ruiz-Pesini, E | 1 |
| Chadderton, N; Farrar, GJ; Gobbo, OL; Kenna, PF; Mansergh, FC | 1 |
| Guttierez, JC; Liu, L; Marella, M; Martinez, JC; Matsuno-Yagi, A; Patki, G; Philip, AL; Thomas, BB; Yagi, T; Zhang, L | 1 |
| Avetisov, SE; Itkis, YS; Karger, EM; Krylova, TD; Lyamzaev, KG; Malakhova, VA; Nevinitsyna, TA; Panteleeva, AA; Ronzina, IA; Sheremet, NL; Tokarchuk, AV; Tsygankova, PG; Zakharova, EY; Zhorzholadze, NV | 1 |
| Amati-Bonneau, P; Bocca, C; Bonneau, D; Bris, C; Chao de la Barca, JM; Chevrollier, A; Chupin, S; Desquiret-Dumas, V; Ferré, M; Gadras, C; Gueguen, N; Kouassi Nzoughet, J; Lenaers, G; Leruez, S; Martinez, MC; Miléa, D; Procaccio, V; Prunier-Mirebeau, D; Reynier, P; Safiedeen, Z; Simard, G; Tessier, L; Verny, C | 1 |
| Marella, M; Matsuno-Yagi, A; Seo, BB; Thomas, BB; Yagi, T | 1 |
| Anklin, C; Erb, M; Gueven, N; Heitz, FD; Pernet, V; Robay, D | 1 |
| Bernazzi, B; Bucchi, L; Carelli, V; Martinuzzi, A; Rengo, C; Torroni, A; Valentino, M; Vergani, L; Zampieron, C | 1 |
| Cerná, L; Hansíková, H; Houst'ková, H; Houstek, J; Kaplanová, V; Misovicová, N; Zeman, J | 1 |
| Beretta, S; Carelli, V; Ferrarese, C; Martinuzzi, A; Mattavelli, L; Sala, G; Schapira, AH; Tremolizzo, L | 1 |
| Achilli, A; Barbiroli, B; Barboni, P; Baruzzi, A; Bucchi, L; Carelli, V; Dotti, M; Federico, A; Ghelli, A; Lodi, R; Lugaresi, A; Rengo, C; Torroni, A; Valentino, ML | 1 |
| Beretta, S; Derham, B; Ferrarese, C; Osborne, NN; Sala, G; Tremolizzo, L; Wood, JP | 1 |
| Carelli, V; Ghelli, A; Martinuzzi, A; Porcelli, AM; Rugolo, M; Zanna, C | 1 |
| Cavelier, L; Collins-Schramm, HE; Cortopassi, GA; McGrogan, M; Savontaus, ML; Seldin, MF; Wong, A | 1 |
17 other study(ies) available for rotenone and Hereditary Optic Neuroretinopathy
| Article | Year |
|---|---|
New Insights on Rotenone Resistance of Complex I Induced by the m.11778G>A/
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Conserved Sequence; Drug Resistance; Electron Transport Complex I; Models, Molecular; Mutation; Optic Atrophy, Hereditary, Leber; Protein Binding; Protein Conformation; Rotenone; Structure-Activity Relationship; Uncoupling Agents | 2022 |
HLA-Homozygous iPSC-Derived Mesenchymal Stem Cells Rescue Rotenone-Induced Experimental Leber's Hereditary Optic Neuropathy-like Models In Vitro and In Vivo.
Topics: Animals; Induced Pluripotent Stem Cells; Mesenchymal Stem Cells; Mice; Optic Atrophy, Hereditary, Leber; Retinal Ganglion Cells; Rotenone | 2023 |
Involvement of endoplasmic reticulum stress in rotenone-induced leber hereditary optic neuropathy model and the discovery of new therapeutic agents.
Topics: Aniline Compounds; Animals; Cells, Cultured; Disease Models, Animal; DNA, Mitochondrial; Drug Discovery; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stress; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Molecular Targeted Therapy; Mutation; Optic Atrophy, Hereditary, Leber; Piperazines; Reactive Oxygen Species; Retina; Retinal Degeneration; Rotenone | 2021 |
Food derived respiratory complex I inhibitors modify the effect of Leber hereditary optic neuropathy mutations.
Topics: Apoptosis; Capsaicin; Cell Line; DNA, Mitochondrial; Electron Transport Complex I; Enzyme Inhibitors; Food Analysis; Furans; Gene-Environment Interaction; Humans; Optic Atrophy, Hereditary, Leber; Oxidative Phosphorylation; Oxygen Consumption; Point Mutation; Rotenone; Xenobiotics | 2018 |
Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy.
Topics: Animals; Cell- and Tissue-Based Therapy; Cells, Cultured; Dependovirus; Disease Models, Animal; Electron Transport Complex I; Genetic Markers; Magnetic Resonance Imaging; Mice; Mitochondria; Mutation; Optic Atrophy, Hereditary, Leber; Optic Nerve; Retina; Retinal Ganglion Cells; Rotenone; Saccharomyces cerevisiae Proteins; Stem Cell Transplantation; Stem Cells | 2014 |
Long-term evaluation of Leber's hereditary optic neuropathy-like symptoms in rotenone administered rats.
Topics: Animals; Disease Models, Animal; Electroretinography; Evoked Potentials, Visual; Humans; Microspheres; Optic Atrophy, Hereditary, Leber; Rats; Rotenone; Superior Colliculi; Tomography, Optical Coherence | 2015 |
Previously Unclassified Mutation of mtDNA m.3472T>C: Evidence of Pathogenicity in Leber's Hereditary Optic Neuropathy.
Topics: Adult; Blood Platelets; Cells, Cultured; DNA, Mitochondrial; Female; Fibroblasts; High-Throughput Nucleotide Sequencing; Humans; Male; NADH Dehydrogenase; Optic Atrophy, Hereditary, Leber; Oxygen Consumption; Polymorphism, Single Nucleotide; Reactive Oxygen Species; Rotenone; Sequence Analysis, DNA; Young Adult | 2016 |
The metabolomic signature of Leber's hereditary optic neuropathy reveals endoplasmic reticulum stress.
Topics: Adult; Aged; Cells, Cultured; Cohort Studies; DNA, Mitochondrial; Electron Transport Complex I; Endoplasmic Reticulum Stress; Female; Fibroblasts; Gene Expression Regulation; Humans; Insecticides; Male; Metabolomics; Middle Aged; Mutation; Optic Atrophy, Hereditary, Leber; Pyridines; Rotenone; Young Adult | 2016 |
Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model.
Topics: Animals; Cell Line; Genetic Therapy; Male; Microscopy, Electron; Mitochondria; NADH Dehydrogenase; Optic Atrophy, Hereditary, Leber; Optic Nerve; Rats; Rats, Long-Evans; Retinal Ganglion Cells; Rotenone; Yeasts | 2010 |
Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy.
Topics: Administration, Oral; Animals; Antioxidants; Cell Line; Cell Survival; Disease Models, Animal; Drug Administration Schedule; Electron Transport Complex I; Humans; Intravitreal Injections; Male; Mice; Mitochondria; Mutation; Optic Atrophy, Hereditary, Leber; Retinal Ganglion Cells; Rotenone; Ubiquinone; Visual Acuity | 2012 |
Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy.
Topics: Clone Cells; Culture Media; DNA, Mitochondrial; Electron Transport Complex I; Enzyme Inhibitors; Europe; Humans; Hybrid Cells; Mutation; NADH, NADPH Oxidoreductases; Optic Atrophy, Hereditary, Leber; Oxygen Consumption; Polymorphism, Restriction Fragment Length; Rotenone; Tumor Cells, Cultured | 2002 |
Segregation pattern and biochemical effect of the G3460A mtDNA mutation in 27 members of LHON family.
Topics: Alanine; Analysis of Variance; DNA Mutational Analysis; DNA, Mitochondrial; Family Health; Female; Glycine; Humans; Longitudinal Studies; Male; NAD; Optic Atrophy, Hereditary, Leber; Oxidoreductases; Pedigree; Point Mutation; Rotenone | 2004 |
Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines.
Topics: Amino Acid Transport System X-AG; Biological Transport; Cell Line, Tumor; DNA, Mitochondrial; Energy Metabolism; Excitatory Amino Acid Transporter 1; Glutamates; Humans; Hydrogen Peroxide; Mutation; Optic Atrophy, Hereditary, Leber; Reactive Oxygen Species; Rotenone; Uncoupling Agents | 2004 |
The ND1 gene of complex I is a mutational hot spot for Leber's hereditary optic neuropathy.
Topics: Adult; Aged; DNA Mutational Analysis; DNA, Mitochondrial; Family Health; Female; Ferricyanides; Glutamic Acid; Haplotypes; Humans; Inhibitory Concentration 50; Lysine; Magnetic Resonance Spectroscopy; Male; Microscopy, Electron, Transmission; Middle Aged; Mitochondria, Muscle; Models, Molecular; Muscle, Skeletal; Mutation; NAD; NADH Dehydrogenase; Occipital Lobe; Optic Atrophy, Hereditary, Leber; Pedigree; Polymorphism, Restriction Fragment Length; Radionuclide Imaging; Rotenone; Sequence Analysis, Protein; Succinate Dehydrogenase; Visual Acuity; Visual Fields | 2004 |
Partial mitochondrial complex I inhibition induces oxidative damage and perturbs glutamate transport in primary retinal cultures. Relevance to Leber Hereditary Optic Neuropathy (LHON).
Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Electron Transport Complex I; Energy Metabolism; Excitatory Amino Acid Transporter 1; Free Radicals; Glutamic Acid; Lipid Peroxidation; Mitochondria; Neuroglia; Neurons; Optic Atrophy, Hereditary, Leber; Oxidative Stress; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; Rotenone; Uncoupling Agents | 2006 |
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids.
Topics: Antioxidants; Apoptosis; Cell Survival; Galactose; Glutathione; Glutathione Disulfide; Humans; Hybrid Cells; Optic Atrophy, Hereditary, Leber; Oxidants; Oxidative Stress; Rotenone; tert-Butylhydroperoxide; Tumor Cells, Cultured | 2008 |
Differentiation-specific effects of LHON mutations introduced into neuronal NT2 cells.
Topics: Animals; Astrocytes; Blindness; Cell Differentiation; Cell Line; DNA, Mitochondrial; Humans; Membrane Potentials; Mutation; Neurons; Optic Atrophy, Hereditary, Leber; Rats; Reactive Oxygen Species; Rotenone; Uncoupling Agents | 2002 |